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Journal articles on the topic 'Breakthrough pain'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Mercadante, Sebastiano, and Eduardo Arcuri. "Breakthrough Pain." Current Drug Therapy 5, no. 1 (2010): 62–66. http://dx.doi.org/10.2174/1574885511005010062.

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2

Gaertner, Jan, and Raymond Voltz. "Breakthrough Pain." Journal of Palliative Medicine 13, no. 3 (2010): 345. http://dx.doi.org/10.1089/jpm.2010.9856.

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3

McCaffery, Margo, and Chris Pasero. "Breakthrough Pain." AJN, American Journal of Nursing 103, no. 4 (2003): 83–86. http://dx.doi.org/10.1097/00000446-200304000-00027.

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4

Ballantyne, Jane C. "Breakthrough pain." PAIN 157, no. 12 (2016): 2621–22. http://dx.doi.org/10.1097/j.pain.0000000000000684.

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5

Dua, Naresh, Ashish Gandhi, Pradeep Jain, and Jayashree Sood. "Breakthrough pain." Current Medicine Research and Practice 5, no. 5 (2015): 228–31. http://dx.doi.org/10.1016/j.cmrp.2015.08.004.

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6

Husić, Samir, Dženita Ljuca, Senad Izić, and Hasan Karahasan. "The effect of breakthrough pain on heart and lung function during the cancer pain treatment in palliative care." Journal of Health Sciences 1, no. 2 (2011): 103–9. http://dx.doi.org/10.17532/jhsci.2011.122.

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Introduction: The aim of the research was to determine the effect of breakthrough pain (BTP) on heart and lung function in patients whose cancer pain had been treated with strong opiates.Methods: A prospective study was conducted on 80 patients who were treated in recumbent patients’ hospice of Palliative Care Centre (hospice) University Clinical Centre Tuzla. The effect of pain breakthrough onheart function was monitored by blood pressure and pulse measuring outside. The effect on respiratory function was monitored by measuring the respiration number with SpO2 and pCO2 and pO2 capillary blood

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7

Narain, Leslie, Rida Naeem, Apurva Nemala, Daniel Linder, Zhuo Sun, and Lufei Young. "Conceptualizing breakthrough pain." Journal of Nursing Education and Practice 11, no. 12 (2021): 46. http://dx.doi.org/10.5430/jnep.v11n12p46.

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The concept of breakthrough pain (BTP) is examined through the development of a conceptual model with a long-term goal of positively impacting the management of chronic pain patients who experience BTP when hospitalized. The model is based on a 2008 Health Economic Model of Breakthrough Pain developed by Abernethy, Wheeler, and Fortner, which will be referred to as the parent model. The conceptual model of BTP, titled, Novel Conceptual Model of Breakthrough Pain (NCMBP) shares a similar structure in regards to the relationships of major constructs. Like the parent model, the NCMBP is based on

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8

Sabato, Alessandro Fabrizio. "Idiopathic Breakthrough Pain." Clinical Drug Investigation 30 (July 2010): 27–29. http://dx.doi.org/10.2165/1158410-s0-000000000-00000.

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9

Fine, Perry G. "Breakthrough Cancer Pain." CNS Drugs 13, no. 5 (2000): 313–19. http://dx.doi.org/10.2165/00023210-200013050-00002.

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10

Enck, Robert E. "Managing breakthrough pain." American Journal of Hospice and Palliative Medicine® 17, no. 6 (2000): 366–67. http://dx.doi.org/10.1177/104990910001700601.

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11

Mercadante, Sebastiano, and Russell K. Portenoy. "Breakthrough cancer pain." PAIN 157, no. 12 (2016): 2657–63. http://dx.doi.org/10.1097/j.pain.0000000000000721.

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12

Seo, Min Seok, and Jae Yong Shim. "Breakthrough Cancer Pain." Korean Journal of Hospice and Palliative Care 18, no. 1 (2015): 1–8. http://dx.doi.org/10.14475/kjhpc.2015.18.1.1.

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13

Gómez-Batiste, Xavier, Federico Madrid, Francisco Moreno, et al. "Breakthrough Cancer Pain." Journal of Pain and Symptom Management 24, no. 1 (2002): 45–52. http://dx.doi.org/10.1016/s0885-3924(02)00421-9.

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14

Mercadante, Sebastiano. "Managing Breakthrough Pain." Current Pain and Headache Reports 15, no. 4 (2011): 244–49. http://dx.doi.org/10.1007/s11916-011-0191-5.

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15

Davies, A. N., A. Dickman, C. Reid, A. M. Stevens, and G. Zeppetella. "Breakthrough cancer pain." BMJ 337, no. 25 1 (2008): a2689. http://dx.doi.org/10.1136/bmj.a2689.

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16

Dedi Artha Nugraha, I. Dewa Gede, and I. Putu Eka Widyadharma. "Breakthrough Cancer Pain." International Journal of Research and Review 10, no. 1 (2023): 344–51. http://dx.doi.org/10.52403/ijrr.20230137.

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Health Organization defined breakthrough pain as a temporary increase in pain from pre-existing underlying pain with moderate to severe pain intensity. Cancer patients with chronic pain experience breakthrough cancer pain during their illness. Breakthrough cancer pain caused high morbidity in patients that disrupts the quality of life of patients and their families. Until now, the causes of breakthrough cancer pain are multifactorial and subjective, therefore the assessment and management are very complex. This article aimed to provide a comprehensive and focused review from the definition to

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17

Mercadante, Sebastiano, Lukas Radbruch, Augusto Caraceni, et al. "Episodic (breakthrough) pain." Cancer 94, no. 3 (2002): 832–39. http://dx.doi.org/10.1002/cncr.10249.

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18

Pochop, Lukáš. "Factors affecting breakthrough pain." Onkologie 13, no. 4 (2019): 162–66. http://dx.doi.org/10.36290/xon.2019.031.

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19

Randive, Seema, and Vivek Mehta. "Breakthrough Pain-Novel Analgesics." Current Clinical Pharmacology 7, no. 2 (2012): 116–20. http://dx.doi.org/10.2174/157488412800228893.

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20

Skarf, Lara Michal, and Craig D. Blinderman. "Cancer-Related Breakthrough Pain." Journal of Palliative Medicine 11, no. 5 (2008): 790–91. http://dx.doi.org/10.1089/jpm.2008.9899.

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21

&NA;. "MANAGING NOCTURNAL BREAKTHROUGH PAIN." Nursing 25, no. 10 (1995): 20. http://dx.doi.org/10.1097/00152193-199510000-00009.

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22

Olay, L., and G. Rijo. "Breakthrough pain in radiotherapy." Reports of Practical Oncology & Radiotherapy 18 (June 2013): S363. http://dx.doi.org/10.1016/j.rpor.2013.03.583.

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23

Narayana, Arvind, Nathaniel Katz, Alicia C. Shillington, et al. "National Breakthrough Pain Study." PAIN 156, no. 2 (2015): 252–59. http://dx.doi.org/10.1097/01.j.pain.0000460305.41078.7d.

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24

Davies, Andrew N. "Cancer-related breakthrough pain." British Journal of Hospital Medicine 67, no. 8 (2006): 414–16. http://dx.doi.org/10.12968/hmed.2006.67.8.21960.

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25

Dawson, Eleanor, Katie Greenfield, Bernie Carter, et al. "Definition and Assessment of Paediatric Breakthrough Pain: A Qualitative Interview Study." Children 11, no. 4 (2024): 485. http://dx.doi.org/10.3390/children11040485.

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Infants, children and young people with life-limiting or life-threatening conditions often experience acute, transient pain episodes known as breakthrough pain. There is currently no established way to assess breakthrough pain in paediatric palliative care. Anecdotal evidence suggests that it is frequently underdiagnosed and undertreated, resulting in reduced quality of life. The development of a standardised paediatric breakthrough pain assessment, based on healthcare professionals’ insights, could improve patient outcomes. This study aimed to explore how healthcare professionals define and a

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26

Fan, Zu-Yan, Jin-Xiang Lin, Xing Li, Xiang-Wei Chen, and Xiu-Yan Huang. "The effect of pain self-management based on pain control diary on breakthrough pain." Journal of Clinical Oncology 35, no. 15_suppl (2017): 10107. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.10107.

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10107 Background: Most patients suffer from cancer pain, especially breakthrough pain. The overall incidence of breakthrough pain is estimated to be 65%. Self-management makes patients actively participating in the use of drugs, transforming their roles and adjusting their moods in order to better cure their own diseases. Therefore, the aim of the study is to discuss the effect of reducing cancer pain patients' breakthrough pain through self-management based on pain control diary. Methods: From October, 2015 to October, 2016, a total of 200 patients treated with opioids for cancer pain were ra

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27

Pasero, Christine L., Margo McCaffery, and Lynda F. McKitrick. "Pain Control: Planning for Breakthrough Cancer Pain." American Journal of Nursing 96, no. 6 (1996): 24. http://dx.doi.org/10.2307/3464883.

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28

Pasero, Chris, and Margo McCaffery. "Pain Control: Managing Breakthrough Pain with OTFC." American Journal of Nursing 99, no. 4 (1999): 20. http://dx.doi.org/10.2307/3472219.

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29

Manchikanti, Laxmaiah. "Breakthrough Pain in Chronic Non-Cancer Pain: Fact, Fiction, or Abuse." Pain Physician 3;14, no. 2;3 (2011): E103—E117. http://dx.doi.org/10.36076/ppj.2011/14/e103.

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Treatment of chronic non-cancer pain with opioid therapy has escalated in recent years, resulting in exploding therapeutic use and misuse of prescription opioids and multiple adverse drug events. Breakthrough pain is defined as a transient exacerbation of pain experienced by individuals who have relatively stable and adequately controlled baseline cancer pain. Further, the definition of breakthrough pain, prevalence, characteristics, implications, and treatment modalities have been extensively described for chronic cancer pain. However, the literature for breakthrough pain in chronic non-cance

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30

Roofthooft, Eva, Noémie Lippens, Steffen Rex, et al. "Breakthrough pain during cesarean section under neuraxial anesthesia: a two-center prospective audit." Acta Anaesthesiologica Belgica 73, no. 1 (2022): 23–29. http://dx.doi.org/10.56126/73.1.04.

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Worldwide, most Cesarean sections (CS) are performed under neuraxial anesthesia. However, neuraxial anesthesia can fail and intraoperative breakthrough pain can occur. The aim of the present investigation was to evaluate the incidence of breakthrough pain in consecutive CS and to describe the potential risk factors for breakthrough pain. In a two center, prospective audit all CS performed under neuraxial anesthesia were included and the occurrence of breakthrough pain as well as all possible risk factors of breakthrough pain were recorded as well as the alternative anesthetic strategy. A total

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31

Simon, MD, RPh, Steve, Daniel S. Bennett, MD, Richard Rauck, MD, Donald Taylor, MD, and Steven Shoemaker, MD. "Breakthrough pain in opioid-treated patients with neuropathic pain." Journal of Opioid Management 2, no. 6 (2006): 347. http://dx.doi.org/10.5055/jom.2006.0051.

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Objective: This report aims to describe the prevalence and characteristics of breakthrough pain in patients with neuropathic pain.Methods: The study represents data from a subset of patients from a larger survey of 228 patients with chronic noncancer pain. Patients were identified from nine pain programs and were administered a telephone questionnaire. The study population comprised 45 chronic noncancer pain patients with primary neuropathic pain diagnoses who were being treated with opioids.Results: Pain had been present for a median of six years. Medications used for pain in addition to opio

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32

Davis, Mellar P. "Breakthrough Pain in Cancer Patients— Characteristics, Impact, and Assessment." Oncology & Hematology Review (US) 07, no. 01 (2011): 12. http://dx.doi.org/10.17925/ohr.2011.07.1.12.

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Breakthrough pain (brief flares of severe pain superimposed on baseline pain) is a common problem in patients with cancer and is associated with significant physical, psychologic and economic burdens on patients and carers. The successful management of breakthrough pain is dependent on the accurate diagnosis and adequate assessment of the patient, which in turn leads to appropriate and effective treatment. It is clear that the impact of breakthrough pain on patients is wide ranging, affecting patient quality of life, decreasing physical functioning, and often leading to psychologic consequence

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33

Mercadante, Sebastiano. "Pharmacotherapy for Breakthrough Cancer Pain." Drugs 72, no. 2 (2012): 181–90. http://dx.doi.org/10.2165/11597260-000000000-00000.

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34

Howell, Julian. "Pharmacotherapy for Breakthrough Cancer Pain." Drugs 72, no. 7 (2012): 1009. http://dx.doi.org/10.2165/11631050-000000000-00000.

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35

Hakl, Marek. "Non malignant breakthrough pain treatment." Neurologie pro praxi 20, no. 5 (2019): 392–94. http://dx.doi.org/10.36290/neu.2019.146.

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36

Sláma, Ondřej. "Management of Breakthrough Cancer Pain." Klinicka onkologie 26, no. 3 (2013): 191–94. http://dx.doi.org/10.14735/amko2013191.

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37

McCaffery, Margo, and Lynda F. McKitrick. "Planning for Breakthrough Cancer Pain." American Journal of Nursing 96, no. 6 (1996): 24. http://dx.doi.org/10.1097/00000446-199606000-00037.

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38

Mercadante, Sebastiano. "Treating breakthrough pain in oncology." Expert Review of Anticancer Therapy 18, no. 5 (2018): 445–49. http://dx.doi.org/10.1080/14737140.2018.1443813.

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39

&NA;, &NA;. "Fentanyl Lollipops for Breakthrough Pain." AJN, American Journal of Nursing 90, no. 1 (1990): 87–88. http://dx.doi.org/10.1097/00000446-199001000-00052.

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40

&NA;. "Onsolis Approved for Breakthrough Pain." Oncology Times 31, no. 17 (2009): 6. http://dx.doi.org/10.1097/01.cot.0000360978.89377.23.

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41

Pasero, Chris, and Margo McCaffery. "Managing Breakthrough Pain with OTFC." American Journal of Nursing 99, no. 4 (1999): 20. http://dx.doi.org/10.1097/00000446-199904000-00014.

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42

Lossignol, Dominique A., and Cristina Dumitrescu. "Breakthrough pain: progress in management." Current Opinion in Oncology 22, no. 4 (2010): 302–6. http://dx.doi.org/10.1097/cco.0b013e32833a873a.

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43

Løhre, Erik T., Morten Thronæs, and Pål Klepstad. "Breakthrough cancer pain in 2020." Current Opinion in Supportive and Palliative Care 14, no. 2 (2020): 94–99. http://dx.doi.org/10.1097/spc.0000000000000494.

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44

McCarberg, Bill H. "The Treatment of Breakthrough Pain." Pain Medicine 8, suppl 1 (2007): S8—S13. http://dx.doi.org/10.1111/j.1526-4637.2006.00270.x.

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45

Driver, Larry C. "Case Studies in Breakthrough Pain." Pain Medicine 8, suppl 1 (2007): S14—S18. http://dx.doi.org/10.1111/j.1526-4637.2006.00271.x.

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46

Fogarty, Mary. "How to manage breakthrough pain." Oncology Times 4, no. 7 (2007): 15. http://dx.doi.org/10.1097/01434893-200707000-00016.

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47

Mercadante, Sebastiano, and Arturo Cuomo. "Breakthrough Cancer Pain: Ten Commandments." Value in Health 19, no. 5 (2016): 531–36. http://dx.doi.org/10.1016/j.jval.2016.03.002.

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48

Mercadante, Sebastiano. "Breakthrough pain in cancer patients." Current Opinion in Anaesthesiology 28, no. 5 (2015): 559–64. http://dx.doi.org/10.1097/aco.0000000000000224.

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49

Zeppetella, G. "Breakthrough Pain in Cancer Patients." Clinical Oncology 23, no. 6 (2011): 393–98. http://dx.doi.org/10.1016/j.clon.2010.12.002.

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50

Pappagallo, Marco. "Breakthrough Pain in Cancer Patients— Pharmacologic Symptomatic Treatment." Oncology & Hematology Review (US) 07, no. 01 (2011): 17. http://dx.doi.org/10.17925/ohr.2011.07.1.17.

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Breakthrough pain is experienced by many cancer patients who are being treated with opioids for the management of chronic persistent pain. There is currently no ‘gold standard’ approach for the pharmacologic symptomatic treatment of breakthrough pain but proposed strategies include the implementation of primary therapies (e.g. chemotherapy, radiotherapy, and surgery) for the underlying cause of the pain; optimization of scheduled analgesia; use of adjuvants; and specific supplemental analgesia for breakthrough pain (the most common pharmacologic strategy). Individualization of treatment is imp

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