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Journal articles on the topic 'Breast cancer, pregnancy, chemotherapy, radiotherapy'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

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1

Koca, Timur, Zuleyha Akgun, Serap Baskaya Yucel, Nihal Zerman Dag, and Mehmet Teomete. "Pregnancy a short time after multimodal therapy for bilateral breast cancer: A case report and review of literature." Journal of Oncology Pharmacy Practice 17, no. 4 (2010): 440–43. http://dx.doi.org/10.1177/1078155210384755.

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Pregnancy occurring after multimodal therapy in a woman with breast cancer with a 1-year follow-up period is a relatively rare condition and has been defined as pregnancy-associated breast cancer. A patient can become pregnant after chemotherapy for breast cancer while she is on tamoxifen. However, the effects of tamoxifen on fetus and on the course of the pregnancy are still unknown. Here, we present a 39-year-old woman treated with chemotherapy and radiotherapy for bilateral breast cancer, and who became pregnant while taking tamoxifen.

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Bao, Weichao, Xiaolin Ma, Yuan Xue, Xin Zou, and Ying Guo. "Pregnancy-associated triple-negative breast cancer: A case report and literature review." Medicine 103, no. 41 (2024): e40059. http://dx.doi.org/10.1097/md.0000000000040059.

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Rationale: The incidence of pregnancy-associated breast cancer (PABC) is relatively low, but it has been increasing in recent years. The onset of PABC causes serious harm to the fetus and the mother due to the unique physiological characteristics of pregnancy, which poses a particular challenge to clinicians. This article reports a case of pregnancy-associated triple-negative breast cancer and describes the patient characteristics and systematic treatment of this type of breast cancer. Patient concerns: A 33-year-old woman was admitted to hospital with a left breast mass that had appeared more

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Bomfim, Renata Oliveira Marques, and Luciano de Oliveira Souz Tourinho. "CÂNCER DE MAMA NA GESTAÇÃO: UMA REVISÃO DAS ABORDAGENS TERAPÊUTICAS." Revista ft 29, no. 146 (2025): 28–29. https://doi.org/10.69849/revistaft/pa10202505291928.

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INTRODUCTION. Breast cancer during pregnancy (BCGA) is a complex condition that requires careful therapeutic approaches to ensure the safety of both mother and fetus. The treatment of BCGA involves ethical and practical dilemmas, since modalities such as chemotherapy, radiotherapy, and hormonal therapy can pose risks to fetal development, especially when administered at certain times of pregnancy. In addition, physiological changes during pregnancy – such as increased mammary vascularization and hormonal changes – can make early diagnosis difficult, resulting in tumors often being identified a

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IONESCU, Olivia, and Nicolae BACALBASA. "Gestational breast cancer. Surgical treatment, pregnancy and fetal outcome." Romanian Journal of Medical Practice 12, no. 2 (2017): 16–22. http://dx.doi.org/10.37897/rjmp.2017.1.3.

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Background. Gestational breast cancer (GBC) is also known as pregnancy-associated breast cancer and it comprises all the breast cancers (BCs) which are diagnosed either during pregnancy or in the first year after delivery or during the lactation period. At present it has been confirmed that the breast malignancies are the most common forms of cancer in pregnant women with a constant increase in its incidence because of the continuous postpone in childbearing especially in women older than 40 years. However, when diagnosed during the pregnancy, the treatment modalities of the BC are complex and

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Upadhyay, Ruchi, Qurat-Ul-Ain Butt, Abraham Hamaoui, Cassandra Henderson, Sydney McCalla, and Hamid Gilak. "Triple Negative Breast Cancer in Pregnancy and Postpartum: Two Case Reports in Hispanic Women." Case Reports in Obstetrics and Gynecology 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/856931.

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Objective. Despite studies suggesting that triple negative breast cancer is more often seen in women of African ancestry, we report here two cases of pregnancy associated triple negative breast cancer in Hispanic women.Cases. Case one is a 37-year-old female para 2-0-0-2, who presented with a left breast mass, at 19 weeks of gestation, the biopsy of which reported an invasive ductal carcinoma, found to be triple receptor negative. The patient underwent chemotherapy during the pregnancy and was delivered with a cesarean at 37 weeks for obstetric indication. After delivery, the patient completed

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Poggio, Francesca, Marco Tagliamento, Chiara Pirrone, et al. "Update on the Management of Breast Cancer during Pregnancy." Cancers 12, no. 12 (2020): 3616. http://dx.doi.org/10.3390/cancers12123616.

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The diagnosis of breast cancer during pregnancy represents a challenging situation for the patient, her caregivers and physicians. Pregnancy adds complexity to oncological treatment planning, as many therapies can be potentially dangerous to the fetus. Therefore, a multidisciplinary approach is needed to offer a proper care for obtaining the best possible outcomes for the mother and the future child. Breast surgery is feasible throughout the pregnancy while radiotherapy should be postponed after delivery. Administration of chemotherapy is considered safe and can be given during the second and

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Simionescu, Anca A., Alexandra Horobeț, Lucian Belaşcu, and Dragoş Mircea Median. "Real-World Data Analysis of Pregnancy-Associated Breast Cancer at a Tertiary-Level Hospital in Romania." Medicina 56, no. 10 (2020): 522. http://dx.doi.org/10.3390/medicina56100522.

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Background and objectives: Breast cancer is among the most common cancer types encountered during pregnancy. Here, we aimed to describe the characteristics, management, and outcomes of women with pregnancy-associated breast cancer at a tertiary-level hospital in Romania. Material and Methods: We retrospectively and prospectively collected demographic, oncological, and obstetrical data for women diagnosed with cancer during pregnancy, and who elected to continue their pregnancy, between June 2012 and June 2020. Complete data were obtained regarding family and personal medical history and risks

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Galati, Francesca, Valentina Magri, Paula Andrea Arias-Cadena, et al. "Pregnancy-Associated Breast Cancer: A Diagnostic and Therapeutic Challenge." Diagnostics 13, no. 4 (2023): 604. http://dx.doi.org/10.3390/diagnostics13040604.

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Pregnancy-associated breast cancer (PABC) is commonly defined as a breast cancer occurring during pregnancy, throughout 1 year postpartum, or during lactation. Despite being a rare circumstance, PABC is one of the most common types of malignancies occurring during pregnancy and lactation, with growing incidence in developed countries, due both to decreasing age at onset of breast cancer and to increasing maternal age. Diagnosis and management of malignancy in the prenatal and postnatal settings are challenging for practitioners, as the structural and functional changes that the breast undergoe

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Wijaya, Ramesh, Wei Sean Yong, Allen WY Yeo, and Diana TH See. "Managing Breast Cancer Diagnosed in First Trimester Pregnancy: A Case Report." Annals of the Academy of Medicine, Singapore 36, no. 12 (2007): 1024–27. http://dx.doi.org/10.47102/annals-acadmedsg.v36n12p1024.

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Introduction: Breast cancer is the most common malignancy in pregnant women, occurring at a rate of about 1 in 3000 pregnancies. Unfortunately, this will sometimes occur during the firsttrimester of pregnancy and this situation warrants discussion of management options with regard to the mother and child, especially with the current trend of deferring child bearing to a later age. Clinical Picture: We present a 34-year-old primigravida who had a breast lump prior to confirmation of her pregnancy and received her diagnosis of invasive breast cancer at 7 weeks’ amenorrhoea. The oncologic managem

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Aurast, Zuzanna, Marta Dzieciątkowska, Michał Grzejda, and Monika Englert-Golon. "Cancers in pregnancy: a multidisciplinary dilemma." Archives of Medical Science – Civilization Diseases 8, no. 1 (2023): 50–56. http://dx.doi.org/10.5114/amscd/178107.

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Malignancies during pregnancy present a multifaceted challenge, with an incidence of approximately 81–140 cases per 100,000 pregnancies, constituting a statistically rare phenomenon. The number of incidences is constantly growing due to the delay of women’s reproductive decisions. Predominant malignancies include breast cancer, cervical cancer, melanoma, and hematological cancers like Hodgkin’s disease. Physiological gestational changes can lead to delayed diagnosis by masking the cancer’s symptoms. Accurate diagnosis and staging, coupled with considerations of gestational age and assessment o

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Kufel-Grabowska, Joanna. "Fertility and breast cancer." Oncoreview 6, no. 4 (2016): 0. http://dx.doi.org/10.5604/01.3001.0009.5057.

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Breast cancer is the most common cancer among females worldwide. The mean age of breast cancer patients is > 60 yrs old, and it is seldom found in women < 40 yrs old (6.5%) and in very young women < 35 yrs old (0.6%). In young females, fertility and all its aspects are an additional therapeutic challenge. Before initiating treatment, the oncologist should offer effective contraception to be applied throughout the therapy, bearing in mind that fertility preservation is of utmost importance. When it comes to breast cancer in pregnancy, the attending physician should use a therapy which

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Pereira de Godoy, Jose Maria, Lívia Maria Pereira de Godoy, and Maria de Fatima Guerreiro Godoy. "Evolution Of Subclinical Systemic Lymphedema In-Patient With Lipedema And Axillary Dissection." International Journal of Medical Science and Clinical invention 7, no. 07 (2020): 4868–70. http://dx.doi.org/10.18535/ijmsci/v7i07.02.

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Background: The surgical treatments of breast cancer associated or not with axillary drainage and radiotherapy constitute the main cause of secondary upper limb lymphedema. Obesity is a particularly aggravating aspect in patients with lymphedema. Novel concepts of subclinical systemic lymphedeman and clinical systemic lymphedema have recently been described. The aim of the present study was to evaluate the evolution of subclinical systemic lymphedema to upper limb lymphedema following treatment for breast cancer. Case: A 36-year-old female patient had been submitted to treatment for breast can

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Utami, Ajeng Sulistianing, Wahyu Nurchalamshah S, Rosfi Firdha Huzaima, and Tomi Irmayanto. "LEFT CA MAMMAE WITH FEBRILE NEUTROPENIA : A CASE REPORT." Lombok Health And Science Journal 2, no. 1 (2023): 14–17. http://dx.doi.org/10.29303/lhsj.v2i1.2501.

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Introduction: Breast cancer is the most common cancer diagnosed, especially in women, accounting for more than 1 in 10 new cancer diagnoses each year. Physical examination, imaging and biopsy must be done to diagnose breast cancer.1,2 Staging is performed to define prognosis and guide treatment recommendations for patients with a similar prognosis. Chemotherapy, hormone therapy, and targeted therapy are the systemic therapies used in breast cancer management. The therapies option are has an side effect, especially chemotherapy. Chemotherapy induced neutropenia is a common toxicity caused by th

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Michalska, Maria, Kinga Kowalik, Aleksandra Zielińska, et al. "Diagnostic and Therapeutic Challenges in Pregnancy-Associated Breast Cancer: A Literature Review." Quality in Sport 42 (June 16, 2025): 60515. https://doi.org/10.12775/qs.2025.42.60515.

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Introduction: Pregnancy-associated breast cancer (PABC) is an increasingly diagnosed malignancy, typically occurring during pregnancy or within one year postpartum. This review summarizes current knowledge on PABC diagnosis, treatment and clinical management, with attention to both maternal outcomes and fetal safety. Diagnostic: The diagnosis of PABC requires careful consideration of both maternal health and fetal safety. Diagnostic process typically begins with the detection of a palpable mass, followed by ultrasound imaging and biopsy. Mammography and MRI may be used selectively, whereas CT

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Lima, Candice, and Thiago L. Apolinario. "Abstract P3-02-01: Chemotherapy plus immunotherapy in stage IV triple-negative breast cancer patient during pregnancy: a case report." Cancer Research 83, no. 5_Supplement (2023): P3–02–01—P3–02–01. http://dx.doi.org/10.1158/1538-7445.sabcs22-p3-02-01.

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Abstract Introduction Cancer during pregnancy is uncommon but the incidence is increasing, particularly in breast cancer, the most common tumor diagnosed in this scenario. The treatment decision in pregnant patients with triple-negative breast cancer is challenging, even more so in cases with advanced disease. Clinical case A 36-year-old woman was referred to our hospital in January, 2020 with the diagnosis of an early (T2N0M0, stage IIA) invasive carcinoma of no special type triple-negative tumor on the left breast and germinative CHEK2 mutation. She received neoadjuvant treatment with four c

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Alfasi, Ayelet, and Irit Ben-Aharon. "Breast Cancer during Pregnancy—Current Paradigms, Paths to Explore." Cancers 11, no. 11 (2019): 1669. http://dx.doi.org/10.3390/cancers11111669.

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Breast cancer is the most common form of malignancy in pregnant women. The prevalence of pregnancy-associated breast cancer (PABC) is up to 0.04% of pregnancies and is expected to rise in developed countries. PABC represents a unique clinical scenario which requires a delicate balance of risks and benefits for both maternal and fetal well-being. Currently, there is paucity of data regarding the short- and long-term outcomes of in-utero exposure to anti-neoplastic agents. In general, when possible, treatment for PABC should follow the same guidelines as in non-pregnant patients. Surgery, includ

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Findeklee, Sebastian. "Overview Tumour Disease and Oncologic Therapy During Pregnancy." Zeitschrift für Geburtshilfe und Neonatologie 222, no. 02 (2018): 61–65. http://dx.doi.org/10.1055/s-0044-100259.

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AbstractNewly diagnosed cancer in pregnancy is an issue with increasing importance, because fulfilling the wish to have a child is shifted later in life. Tumour disease is diagnosed in around 0.1% of all pregnancies in Germany. Most common tumour entities involve the breast, the cervix and the hematopoietic system. As tumour prognosis is not negatively affected by pregnancy and gestation does not disclude oncologic therapy it is important to plan treatment immediately. Oncologic surgery preserving the uterus is not at all limited. Chemotherapy with anthracyclines, taxanes or platinum derivates

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Lopes Ferraz, Bruna Elias Parreira, Roney César Signorini Filho, Lucas Ribeiro Borges Carvalho, et al. "Maternal and Perinatal Outcomes in Pregnant Women with Cancer: A Single-Center Retrospective Cohort Study." Diagnostics 15, no. 8 (2025): 1012. https://doi.org/10.3390/diagnostics15081012.

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Objective: The aim of our study was to evaluate maternal and perinatal outcomes in pregnant women diagnosed with cancer and treated at a single referral center in Brazil. Methods: This retrospective cohort study analyzed medical records from January 2008 to December 2020. Demographic, clinical, obstetric, and tumor-related variables were assessed. Patients were divided into two groups: Group 1 (n = 28) included women diagnosed with cancer during pregnancy or up to one year postpartum, while Group 2 (n = 11) comprised those who became pregnant during cancer investigation or treatment. Results:

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Martinez Pineda, Wendy Jazmin, Angel Luis Calva Espinosa, Alicia Guillermina Gonzalez Noguez, Carlos Osorio Solis, and Alvar Jose Vacio Olguin. "Tonsil cancer treated with radiotherapy during a pregnancy: a case report." Journal of Radiotherapy in Practice 19, no. 2 (2019): 197–201. http://dx.doi.org/10.1017/s1460396919000608.

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AbstractIntroduction:Cancer during pregnancy has an incidence of 1/1,000, and when diagnosed, the most common ones are breast cancer (1/10,000), Hodgkin’s lymphoma (1/6,000), and head and neck cancer (1/10,000). If a diagnosis is made during pregnancy, the treatment cannot wait until delivery, and there is concern about the effects that radiotherapy may have on the foetus. The multidisciplinary group has to assess and ethically make decisions with regard to the mother and foetus.Clinical case:A 35-year-old female, a carrier of Behcet’s disease, underwent 5 years of treatment with hydroxychloro

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Dasic, Davor, Narendra K. Rath, Mario Ganau, and Zaid Sarsam. "Management Challenges of Metastatic Spinal Cord Compression in Pregnancy." Case Reports in Surgery 2020 (November 1, 2020): 1–11. http://dx.doi.org/10.1155/2020/8891021.

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Primary and secondary spinal tumours with cord compression often represent a challenging condition for the patient and clinicians alike, even more so during pregnancy. The balance between safe delivery of a healthy baby and management of the mother’s disease bears many clinical, psychological, and ethical dilemmas. Pregnancy sets a conflict between the optimal surgical and oncological managements of the mother’s tumour and the well-being of her foetus. We followed the CARE guidelines from the EQUATOR Network to report an exemplificative case of a 39-year-old woman with a 10-year history of bre

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Amant, Frédéric, Gunter von Minckwitz, Sileny N. Han, et al. "Prognosis of Women With Primary Breast Cancer Diagnosed During Pregnancy: Results From an International Collaborative Study." Journal of Clinical Oncology 31, no. 20 (2013): 2532–39. http://dx.doi.org/10.1200/jco.2012.45.6335.

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Purpose We aimed to determine the prognosis of patients with breast cancer diagnosed during pregnancy (BCP). Patients and Methods In this cohort study, a multicentric registry of patients with BCP (from Cancer in Pregnancy, Leuven, Belgium, and GBG 29/BIG 02-03) compiled pro- and retrospectively between 2003 and 2011 was compared with patients who did not have associated pregnancies, using an age limit of 45 years. Patients with a diagnosis postpartum were excluded. The main analysis was performed using Cox proportional hazards regression of disease-free survival (DFS) and overall survival (OS

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Ladodo, Olga B., Mariia V. Iurova, Svetlana V. Khokhlova, et al. "Benefits and limitations of breastfeeding for mothers with malignant tumors." Journal of Modern Oncology 26, no. 1 (2024): 73–79. http://dx.doi.org/10.26442/18151434.2024.1.202571.

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In the modern world breastfeeding (BF) is considered as a significant factor in reducing the risk of developing malignant tumors of the mammary gland and ovaries. However, the problem of maintenance or refusing BF in malignant neoplasms (malignant neoplasms) still remains open. In recent years, there has been a steady increase in breast cancer (BC), especially in developed countries, with more than 10% of all breast malignancies (BC) diagnosed in women under 40 years of age. The presented article highlights aspects of maintaining lactation in different periods of the relevance of BF in relatio

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Zielińska, Martyna Maria, Natalia Zarankiewicz, Aleksandra Kuchnicka, Katarzyna Kosz, and Bogumiła Ciseł. "Pregnancy-associated breast cancer - diagnosis, treatment and outcomes for women and their offspring." Journal of Education, Health and Sport 10, no. 8 (2020): 251–59. https://doi.org/10.12775/JEHS.2020.10.08.029.

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<strong>Zielińska Martyna, Zarankiewicz Natalia, Kuchnicka Aleksandra, Kosz Katarzyna, Ciseł Bogumiła</strong><strong>. Pregnancy-associated breast cancer - diagnosis, treatment and outcomes for women and their offspring. Journal of Education, Health and Sport. 2020;10(8):251‑259. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2020.10.08.029</strong> <strong>https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2020.10.08.029</strong> <strong>https://zenodo.org/record/3992401</strong>                   <strong>The journal has had 5 p

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Huis in 't Veld, Evangeline A., Anouk M. Kruse, Emma J. Verwaaijen, et al. "The First 6 Years’ Experiences of a National Centralized Offspring Surveillance Setting for Dutch Children Prenatally Exposed to Maternal Cancer to Inform Future International Practice: Protocol for a Demographic Review of Referred Families and Key Lessons Learned." JMIR Research Protocols 14 (June 24, 2025): e71612. https://doi.org/10.2196/71612.

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Background Cancer during pregnancy is a rare and significant life-changing event affecting approximately 1 in 1000-2000 pregnancies. With increasing maternal age and broader application of prenatal screening programs such as the Dutch Non-Invasive Prenatal Testing, incidental detection of maternal cancer is becoming more frequent. Advancements in safe treatment options during pregnancy, supported by the International Network on Cancer Infertility and Pregnancy (INCIP), have led to fewer pregnancy terminations. Consequently, more children are exposed to chemotherapy and other cancer treatments

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Rajan, Kiran Kasper, Katherine Fairhurst, Beth Birkbeck, et al. "Abstract PD15-04: PD15-04 Overall survival following breast conserving surgery and adjuvant radiotherapy compared with mastectomy for early stage breast cancer: a systematic review and meta-analysis." Cancer Research 83, no. 5_Supplement (2023): PD15–04—PD15–04. http://dx.doi.org/10.1158/1538-7445.sabcs22-pd15-04.

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Abstract Background Breast conserving surgery with adjuvant radiotherapy (BCS+RT) and mastectomy are currently offered as oncologically equivalent options for the surgical management of early breast cancer based on findings from randomised controlled trials (RCTs) conducted over four decades ago. Since then, locoregional and systemic breast cancer treatments have improved significantly and several recent observational studies suggest a survival advantage in patients receiving BCS+RT compared to those having mastectomy. If BCS+RT is oncologically superior to mastectomy, this may dramatically im

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Mouh, Fatima Zahra, Meriem Slaoui, Rachid Razine, Mohammed EL Mzibri, and Mariam Amrani. "Clinicopathological, Treatment and Event-Free Survival Characteristics in a Moroccan Population of Triple-Negative Breast Cancer." Breast Cancer: Basic and Clinical Research 14 (January 2020): 117822342090642. http://dx.doi.org/10.1177/1178223420906428.

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Introduction: Triple-negative breast cancer (TNBC) is a group of breast carcinoma characterized by the lack of expression of estrogen and progesterone hormone receptors (ER, PgR) and HER2. This form is also characterized by its aggressiveness, a low survival rate, and the absence of targeted therapies. This study was planned to evaluate the clinical features, treatment, and prognosis characteristics of TNBC in a population of Moroccan patients. Methods: In this retrospective study, a total of 905 patients diagnosed with breast cancer at the National Institute of Oncology in Rabat, Morocco, hav

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Turner, Nicholas C., David W. Cescon, Sibylle Loibl, et al. "Abstract OT2-24-02: ZEST: Randomized phase III study evaluating efficacy and safety of niraparib in patients with HER2-negative BRCA-mutated or triple-negative breast cancer with detectable circulating tumor DNA after definitive therapy." Cancer Research 82, no. 4_Supplement (2022): OT2–24–02—OT2–24–02. http://dx.doi.org/10.1158/1538-7445.sabcs21-ot2-24-02.

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Abstract Background: Following definitive treatment, there is no standard-of-care for patients (pts) with HR+HER2− breast cancer (BC) or TNBC beyond clinical monitoring for metastasis. Recurrence rates remain high for pts with a greater burden of residual disease after neoadjuvant chemotherapy. Detectable circulating tumor DNA (ctDNA) is also associated with a high risk of clinical relapse. However, there is no standard therapy for pts with detectable ctDNA who have not yet developed clinical metastasis. Niraparib, a poly(ADP-ribose) polymerase inhibitor (PARPi), inhibits repair of DNA damage

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Mustață, Laura, Nicolae Gică, Radu Botezatu, et al. "Malignant Phyllodes Tumor of the Breast and Pregnancy: A Rare Case Report and Literature Review." Medicina 58, no. 1 (2021): 36. http://dx.doi.org/10.3390/medicina58010036.

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Phyllodes Tumor (PT) is a rare fibroepithelial breast tumor that can behave differently depending on its biologic features. Traditionally, PTs are classified by their histologic features into benign, borderline, and malignant. In most cases that were reported, all PTs may recur, but only the borderline and malignant PT can metastasize. PT usually occurs as a breast lump or accidental finding on ultrasound (US) examination. The clinical features include a well-defined breast mass, regular or lobulated. The diagnosis is based on the integration of morphology features, but remains challenging, pa

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Assogba, Emerline, Caroline Mollévi, Anne-Sophie Woronoff, et al. "Abstract PO5-11-04: Sexuality and fertility profiles, Health-Related Quality of Life and other living conditions of young breast cancer survivors in France: a national cross-sectional study by the French Network of Cancer Registries (FRANCIM)." Cancer Research 84, no. 9_Supplement (2024): PO5–11–04—PO5–11–04. http://dx.doi.org/10.1158/1538-7445.sabcs23-po5-11-04.

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Abstract Introduction In recent decades, the living conditions of breast cancer (BC) survivors have received particular attention, especially among the youngest who face problems related to fertility and sexuality. The main objective of this population-based study was to identify clinical, social and economic determinants of sexuality, fertility and Health Related Quality of Life (HRQoL), and describe other living conditions of young BC survivors in France. Methods Non-metastatic invasive BC women diagnosed from 2009 to 2016, aged ≤ 40 years at diagnosis were identified through the FRANCIM Net

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Cabıoğlu, Neslihan, Hasan Karanlik, Mehmet Ali Gulcelik, et al. "Abstract PD15-01: PD15-01 AXILLARY NODAL RECURRENCE IS RARE IN PATIENTS WITH NODE-POSITIVE BREAST CANCER UNDERGOING SLNB FOLLOWING NEOADJUVANT CHEMOTHERAPY : EARLY RESULTS OF THE NEOSENTITURK-TRIAL/MF-18-03." Cancer Research 83, no. 5_Supplement (2023): PD15–01—PD15–01. http://dx.doi.org/10.1158/1538-7445.sabcs22-pd15-01.

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Abstract Background: Whether axillary lymph node dissection (ALND) following sentinel lymph node biopsy (SLNB) could be spared in patients with initially clinically positive axilla after neoadjuvant chemotherapy (NAC) is still controversial even though recent studies indicate that axillary recurrence seems to be a rare event. Our aim is to find out whether omitting ALND could be oncologically safe in patients undergoing SLNB after NAC. Material and Methods: Of patients presented with c T1-4N1-3M0 disease, those undergoing SLNB after NAC were included in the prospective multicentre registry tri

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Cakmak, Guldeniz Karadeniz, Enver Özkurt, Hasan Karanlık, et al. "Abstract P4-06-06: The Etiologic Causes of Diagnostic Delay in Locally Advanced Breast Cancer: _x000B_A Multicentric Nationwide Trial." Clinical Cancer Research 31, no. 12_Supplement (2025): P4–06–06—P4–06–06. https://doi.org/10.1158/1557-3265.sabcs24-p4-06-06.

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Abstract Purpose: Breast cancer is the most common type of cancer in women worldwide, and early detection in advanced stages is the most crucial factor in reducing mortality and improving quality of life. The aim of the presented study is to investigate patient and region-specific factors causing delays in the diagnosis and treatment of breast cancer in different geographical regions in Türkiye. Method: A survey study has been designed to be conducted between August 2023 and October 2024 in every region, involving women who have been diagnosed with locally advanced breast cancer. The survey co

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Silva Rivas, Fernando Wladimir, José Maria Soares, Bruna Salani Mota, et al. "Abstract P2-09-05: Evaluating the Impact of Mammographic Screening on 5-Year Breast Cancer Survival: A Propensity Score-Adjusted Retrospective Cohort Study in a Tertiary Hospital in São Paulo, Brazil." Clinical Cancer Research 31, no. 12_Supplement (2025): P2–09–05—P2–09–05. https://doi.org/10.1158/1557-3265.sabcs24-p2-09-05.

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Abstract Background: In Brazil, breast cancer (BC) is the most prevalent and deadly form of malignant neoplasia among women. Despite therapeutic advances, late detection remains a significant barrier to achieving a reduction in mortality rates comparable to those observed in developed countries. Organized mammographic screening is advocated as the most effective preventive measure for early detection of cancer in asymptomatic women. The Brazilian government recommends biennial mammography for women aged 50 to 69; however, population coverage is low, and screening is often conducted opportunist

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Cameron, David A., Richard Anderson, Florian Clatot, et al. "Anti-Müllerian hormone (AMH) as a marker of ovarian reserve and premature ovarian insufficiency (POI) in children and women with cancer: A systematic review." Journal of Clinical Oncology 39, no. 15_suppl (2021): e24057-e24057. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e24057.

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e24057 Background: Female patients undergoing anticancer treatment are at elevated risk of ovarian damage including development of POI. AMH is a key serum biomarker of ovarian reserve. However, its role to identify risk of POI in cancer patients prior to and after treatment is less well understood. Methods: A systematic literature search for AMH in women with cancer was conducted up to 30 August 2020, with formal bias assessment. We aimed at evaluating AMH as a biomarker of ovarian reserve and POI before and after anticancer treatment. Exploratory subgroups were based on age, cancer type and l

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Reinert, Tomás, Cristiano P. Souza, Pedro Liedke, et al. "Abstract OT2-22-02: Sequencing of anthracyclines and taxanes during neoadjuvant therapy of locally advanced HER2-negative breast cancer (NEOSAMBA Study/LACOG 0419)." Cancer Research 83, no. 5_Supplement (2023): OT2–22–02—OT2–22–02. http://dx.doi.org/10.1158/1538-7445.sabcs22-ot2-22-02.

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Abstract Background: Breast cancer (BC) is the most frequent cancer in women in Brazil, with more than 60,000 cases estimated annually. Forty percent of patients present with stages III and IV and neoadjuvant chemotherapy (NACT) remains the mainstay of treatment for locally advanced breast cancer (LABC). Taxanes usually follow anthracyclines in breast cancer neo/adjuvant treatment, likely because of their later introduction into clinical practice. However, the potential impact of alternative sequencing remains to be studied. A single-center phase II randomized clinical trial conducted in the B

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Kawano, J., N. Hayashi, A. Yoshida, H. Yagata, and H. Yamauchi. "Pregnancy-Associated Breast Cancer: Chemotherapy During Pregnancy." Annals of Oncology 23 (September 2012): ix133. http://dx.doi.org/10.1016/s0923-7534(20)32937-9.

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Acharya, Sandhya C., and Aarati Shah. "Breast cancer during pregnancy." Grande Medical Journal 1, no. 1 (2019): 52–54. http://dx.doi.org/10.3126/gmj.v1i1.22414.

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Breast cancer during pregnancy is rare accounting for 1 in around 3000 pregnant women as per the American cancer society. According to hospital-based cancer registry of Nepal, breast cancer accounts for 9.2% of total cancer cases and pregnancy associated breast cancer accounts for 0.15% of the total breast cancer. Though rare, breast cancer is the most common type of cancer found during pregnancy and that too in advanced stage because of the hormonal interplay during pregnancy. Here we present a case of breast cancer during pregnancy which was treated successfully with chemotherapy, surgery, r

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Mathelin, Carole, Kadour Annane, Philippe Liegeois, Jean-Pierre Bergerat, and Patrick Dufour. "Chemotherapy for breast cancer during pregnancy." European Journal of Obstetrics & Gynecology and Reproductive Biology 123, no. 2 (2005): 260–62. http://dx.doi.org/10.1016/j.ejogrb.2005.05.012.

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Sasidharan, R., and V. Harvey. "Pregnancy and breast cancer." Obstetric Medicine 3, no. 2 (2010): 54–58. http://dx.doi.org/10.1258/om.2010.090066.

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Breast cancer is one of the most commonly diagnosed malignancies during pregnancy. Pregnancy-associated breast cancer (PABC) presents a challenging clinical situation. This article reviews the current evidence around the management of PABC and the safety of pregnancy after breast cancer. The trend towards later age at first childbirth has resulted in an increase in the number of breast cancer cases coexistent with pregnancy. The management of breast cancer during pregnancy requires a multidisciplinary team approach. Breast surgery can be safely performed during any trimester of pregnancy. Radi

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McArdle, C. S., D. Crawford, E. H. Dykes, et al. "Adjuvant radiotherapy and chemotherapy in breast cancer." British Journal of Surgery 73, no. 4 (1986): 264–66. http://dx.doi.org/10.1002/bjs.1800730407.

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Kulshrestha, Meeta. "Pregnancy-Associated Breast Cancer." Journal of South Asian Federation of Obstetrics and Gynaecology 3, no. 1 (2011): 1–5. http://dx.doi.org/10.5005/jp-journals-10006-1111.

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ABSTRACT The incidence of pregnancy associated with breast cancer can be expected to increase as maternal age at the time of pregnancy continues to increase. Women diagnosed with breast cancer during pregnancy have similar disease characteristics to age-matched controls. Surgical treatment may be performed as for the nonpregnant women. Radiotherapy and endocrine or antibody treatment should be postponed until after delivery. A multidisciplinary approach is recommended for optimal clinical decision-making. But physicians should be aggressive in the work-up of breast symptoms in the pregnant pop

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Dimple, Bhagyasreechandu* &. Dr. Harinatha Reddy Jolapuram. "SUCCESS RATES AND SEQUENCING OF CHEMOANDRADIO THERAPIES IN BREAST CANCER - A RETROSPECTIVE ANALYSIS." Indian Journal of Medical Research and Pharmaceutical Sciences 6, no. 8 (2019): 26–29. https://doi.org/10.5281/zenodo.3380465.

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In breast cancer patients, the ideal time sequences for chemotherapy and radiation therapy remain unknown. Most published trials were conducted including patients with early breast cancer. This retrospective analysis directed at evaluating the optimal sequence in the population for chemotherapy and radiotherapy. Chemotherapy and radiation therapy are typically not administered simultaneously in breast cancer patients due to the extensive use of Anthracyclinebased chemotherapy regimens and concernsabout excessive radiation toxicity with simultaneous treatment. Therefore, the best way to sequenc

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Т., Ф. Татарчук, В. Поминчук Д., and В. Шулига-Недайхлебова О. "Breast cancer and pregnancy." Reproductive Endocrinology, no. 40 (April 30, 2018): 16–22. https://doi.org/10.18370/2309-4117.2018.40.16-22.

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Actuality. Today, the urgency of the problem of breast cancer (breast cancer) can not be said much. The steady increase in the incidence among the female population around the world and the figures are self-evident. In particular, in Ukraine more than 15 thousand new cases of breast cancer are recorded annually. The percentage of breast cancer in pregnant women ranges from 8 to 15% of cases in different countries of Europe. Diagnosis of breast cancer in pregnant women has a number of difficulties in terms of visualization. First of all, it is connected with morphological and structural changes

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Lenhard, Miriam S., Ingo Bauerfeind, and Michael Untch. "Breast cancer and pregnancy: Challenges of chemotherapy." Critical Reviews in Oncology/Hematology 67, no. 3 (2008): 196–203. http://dx.doi.org/10.1016/j.critrevonc.2008.02.007.

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Mkango, Sara B., Nyimvua Shaban, Eunice Mureithi, and Twalib Ngoma. "Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy." Computational and Mathematical Methods in Medicine 2019 (September 11, 2019): 1–12. http://dx.doi.org/10.1155/2019/5216346.

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A type of cancer which originates from the breast tissue is referred to as breast cancer. Globally, it is the most common cause of death in women. Treatments such as radiotherapy, chemotherapy, hormone therapy, immunotherapy, and gene therapy are the main strategies in the fight against breast cancer. The present study aims at investigating the effects of the combined radiotherapy and chemotherapy as a way to treat breast cancer, and different treatment approaches are incorporated into the model. Also, the model is fitted to data on patients with breast cancer in Tanzania. We determine new tre

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Aristei, Cynthia, Isabella Palumbo, and Elisabetta Perrucci. "The Association of Chemotherapy and Radiotherapy: Breast Cancer." Current Drug Therapy 5, no. 3 (2010): 192–201. http://dx.doi.org/10.2174/157488510791561011.

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Wise, J. "Radiotherapy plus chemotherapy is best for breast cancer." BMJ 315, no. 7113 (1997): 899–904. http://dx.doi.org/10.1136/bmj.315.7113.899h.

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Colleoni, M., F. Nole’, I. Minchella, et al. "Pre-operative chemotherapy and radiotherapy in breast cancer." European Journal of Cancer 34, no. 5 (1998): 641–45. http://dx.doi.org/10.1016/s0959-8049(97)10091-0.

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Tubiana-Mathieu, N., C. Lejeune, P. Bonnier, et al. "P66 Inflammatory breast cancer: Chemotherapy and concommittant radiotherapy." European Journal of Cancer 34 (February 1998): S32. http://dx.doi.org/10.1016/s0959-8049(97)89283-0.

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Yuvaraj K, Govindhan E, Francis Kevin Raj S, Pavithra J, and Muralidharan p. "A concise review on breast cancer in pregnancy." International Journal of Science and Research Archive 8, no. 2 (2023): 475–91. http://dx.doi.org/10.30574/ijsra.2023.8.2.0272.

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Breast cancer is major serious cancer in the women, it can be easily treated with chemotherapy drugs or by breast conservation surgery if it is diagnosed earlier. However the condition become even worse in those pregnant women, because chemotherapy is the most common first line prophylaxis treatment for breast cancer. In pregnancy diagnosed with breast cancer reveals a complicated chemotherapy because it affect the fetus and eventually produce fetal abnormalities and decreases the survival chances of fetus. The 50% survival chances of breast cancer patient is increased with the early diagnosis

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Xu, Xiaofei, Yuesong Yin, Lixia Zhang, Dongmiao Wang, Ye Zhou, and Qingxia Li. "Research progress of cardiotoxicity caused by radiotherapy in breast cancer." Precision Radiation Oncology 8, no. 3 (2024): 153–58. http://dx.doi.org/10.1002/pro6.1241.

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AbstractBreast cancer has surpassed lung cancer as the most common type of malignancy worldwide. Treatments for breast cancer include surgery, chemotherapy, radiotherapy, targeted therapy, endocrine therapy, immunotherapy, and hyperthermia. Radiotherapy plays an important role in breast cancer treatment. Patients with early breast cancer can have longer survival after combined treatment, but cardiotoxicity caused by radiotherapy may affect long‐term prognosis. This article reviews cardiac damage caused by radiotherapy in breast cancer.

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