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1

Trupe, Lydia A., Anne Rositch, Lindsay Dickerson, Su Lucas, and Susan C. Harvey. "Knowledge and Attitudes About Breast Cancer in Limpopo, South Africa." Journal of Global Oncology 3, no. 5 (2017): 509–14. http://dx.doi.org/10.1200/jgo.2016.008102.

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Purpose Breast cancer survival is unacceptably low in many low-resource settings, including rural South Africa, where access to screening and treatment services is limited. To describe the context for implementing an early detection program, we assessed knowledge and attitudes toward breast cancer risk, early detection, and treatment. Methods We conducted a cross-sectional survey among 243 women presenting to Hlokomela Clinic in Hoedspruit, South Africa, during April and May 2016. We used quantitative and qualitative analyses to determine levels of knowledge of risk factors, symptoms, and trea
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Lambert, Madeleine, Emily Mendenhall, Andrew Wooyoung Kim, Herbert Cubasch, Maureen Joffe, and Shane A. Norris. "Health system experiences of breast cancer survivors in urban South Africa." Women's Health 16 (January 2020): 174550652094941. http://dx.doi.org/10.1177/1745506520949419.

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Background: Breast cancer is the most common cancer globally and among South African women. Women from socioeconomically disadvantaged South African communities more often present later and receive total mastectomy compared to those from more affluent communities who have more breast conserving surgery (which is less invasive but requires mandatory radiation treatment post-operatively). Standard chemotherapy and total mastectomy treatments are known to cause traumatizing side effects and emotional suffering among South African women; moreover, many women face limited communication with physici
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Prodehl, Leanne, and Carol Benn. "Triple negative breast cancer in a South African urban breast care centre." Journal of Clinical Oncology 35, no. 15_suppl (2017): e13067-e13067. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e13067.

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e13067 Background: Triple negative breast cancer (TNBC) is associated with advanced stage at presentation, aggressive tumour biology and poor outcomes. There is no published data for South Africa. Methods: A retrospective file review of TNBC cases at the Milpark Breast Care Unit in Johannesburg, South Africa, data were collected on presentation, treatment and outcomes. A prospective file review and telephonic interview were done for further follow up. Results: There were 196 patients with TNBC identified out of 1407 patients (13.9%), 135 patients were analysed. Stage at presentation was IIa an
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Kiyange, F., V. Walusansa, G. Mandosela, H. Nzereka Kambale, E. Luyirika, and J. Orem. "The Role of South-to-South Partnerships in Developing Cancer Services in Africa." Journal of Global Oncology 4, Supplement 2 (2018): 163s. http://dx.doi.org/10.1200/jgo.18.21200.

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Background and context: Despite being a growing public health concern in Africa, access to effective cancer treatment and pain relief is still limited in sub-Saharan Africa. The African Palliative Care Association (APCA) in collaboration with the American Cancer Society and the Ministry of Health of Swaziland have successfully implemented a South-to-South partnership which has facilitated the development and operation of a cancer unit in Mbabane National Hospital. Although the cancer burden continues to rise in Africa, many countries do not have established oncology services. They rely on canc
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Jacobs, Inarie, Christine Taljaard-Krugell, Cristian Ricci, et al. "Dietary intake and breast cancer risk in black South African women: the South African Breast Cancer study." British Journal of Nutrition 121, no. 5 (2019): 591–600. http://dx.doi.org/10.1017/s0007114518003744.

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AbstractIncidence rates of breast cancer (BC) are increasing in South Africa. The aim of this study was to investigate the association between dietary intake and BC risk in black South African women. The study population included 396 BC cases and 396 population-based controls matched on age and residence, participating in the South African Breast Cancer study. Diet was assessed using a validated quantified FFQ from which twelve energy-adjusted food groups were formed and analysed. OR were estimated using conditional logistic regressions, adjusted for confounding factors, comparing highestv.low
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Bosire, Edna N., Emily Mendenhall, and Lesley Jo Weaver. "Comorbid Suffering: Breast Cancer Survivors in South Africa." Qualitative Health Research 30, no. 6 (2020): 917–26. http://dx.doi.org/10.1177/1049732320911365.

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Cycles of chronic illness are unpredictable, especially when multiple conditions are involved, and that instability can transform “normal” everyday life for individuals and their families. This article employs a theory of “comorbid suffering” to interpret how multiple concurrent diagnoses produce webs of remarkable suffering. We collected 50 life stories from breast cancer survivors enrolled in the South Africa Breast Cancer Study. We present three women’s narratives who grapple with comorbid suffering and illness-related work, which arise interpersonally when comorbid illnesses affects social
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Moodley, Shun Devan, Alicia McMaster, and Rashem Mothilal. "Taxpas: Epidemiological and Survival Data in Breast Cancer Patients Treated with a Docetaxel-Based Chemotherapy Regimen in South Africa." Journal of Cancer Research 2013 (December 11, 2013): 1–5. http://dx.doi.org/10.1155/2013/308236.

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Breast cancer is the leading cancer among South African women. There is limited South African epidemiological data on triple-negative breast cancer (TNBC). Taxpas was a nonrandomized observational survey conducted in multiple centres in South Africa from April 2004 to December 2010. 1632 female patients diagnosed with breast cancer, with a median age of 51 years, were enrolled in the survey. Patients were treated on a docetaxel-based chemotherapy regimen. The objective of the study was to assess epidemiological data and survival data. The incidence of TNBC was 14%. The one-year survival rate f
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Saberian, Mehran, Kamran Mehrabani, and Hadi Raeisi Shahraki. "Clustering time trends of breast cancer incidence in Africa: a 27-year longitudinal study in 53 countries." African Health Sciences 21, no. 1 (2021): 47–53. http://dx.doi.org/10.4314/ahs.v21i1.8.

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Background: Breast cancer is the most common, frequently diagnosed cancer with the highest incidence among female worldwide. Although the incidence is decreasing in developed countries, it is on increase in most of the African countries.
 Objective: This study aimed to identify different time trends of breast cancer incidence among African countries using latent mixture approach.
 Methods: The information includes newly diagnosed breast cancer patients per 100,000 women for 53 African countries in a period of 1990-2016. Latent mixture modeling was performed in Mplus 7.4 software.&#x0
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Cubasch, Herbert, Paul Ruff, Maureen Joffe, et al. "South African Breast Cancer and HIV Outcomes Study: Methods and Baseline Assessment." Journal of Global Oncology 3, no. 2 (2017): 114–24. http://dx.doi.org/10.1200/jgo.2015.002675.

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Purpose In low- and middle-income, HIV-endemic regions of sub-Saharan Africa, morbidity and mortality from the common epithelial cancers of the developed world are rising. Even among HIV-infected individuals, access to antiretroviral therapy has enhanced life expectancy, shifting the distribution of cancer diagnoses toward non–AIDS-defining malignancies, including breast cancer. Building on our prior research, we recently initiated the South African Breast Cancer and HIV Outcomes study. Methods We will recruit a cohort of 3,000 women newly diagnosed with breast cancer at hospitals in high (ave
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Odedina, Folakemi T., Delva Shamley, Ifeoma Okoye, et al. "Landscape of Oncology Clinical Trials in Africa." JCO Global Oncology, no. 6 (September 2020): 932–41. http://dx.doi.org/10.1200/jgo.19.00189.

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PURPOSE The burden of cancer in Africa is of significant concern for several reasons, including that incidence of cancer in Africa continues to rise while Africa is also dealing with communicable diseases. To combat cancer in Africa, oncology clinical trials are needed to develop innovative interventions for cancer prevention, screening, diagnosis, treatment, and survivorship. Unfortunately, there is a paucity of clinical trials in Africa and it is difficult for African clinicians to get information on open oncology clinical trials and impossible for African patients with cancer to access this
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Kayamba, Violet, Wilbroad Mutale, Holly Cassell, Douglas Corbett Heimburger, and Xiao-Ou Shu. "Systematic Review of Cancer Research Output From Africa, With Zambia as an Example." JCO Global Oncology, no. 7 (May 2021): 802–10. http://dx.doi.org/10.1200/go.21.00079.

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PURPOSE Cancer occurrence is increasing in Africa, although research has lagged. The objective of this review was to analyze cancer research outputs from Africa, with a particular focus on Zambia. METHODS We searched PubMed for published cancer-related articles from African countries. All articles reporting on cancer in Africa were considered. We conducted analyses to explore correlations between cancer research output and total population, gross domestic product, and new cancer cases recorded in 2020. For Zambia articles, we also analyzed cancer types and time trends. RESULTS A total of 48,48
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Vargas-Hernández, Víctor Manuel. "Risk Factors Associated with Breast Cancer." Journal of Hematology and Oncology Research 4, no. 1 (2020): 1–5. http://dx.doi.org/10.14302/issn.2372-6601.jhor-20-3544.

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In Mexico, breast cancer is the second most common site of cancer in women and in most developed and emerging countries. Incidence rates have increased in many countries, although in some, mortality has remained stable with a slight reduction. There are geographical differences with high rates of breast cancer in North America, Northern Europe and Oceania, and lower rates in Central and South America, South and East Europe; in addition to emerging countries in Africa and Asia. Genetic and hereditary factors constitute less than 5% of breast cancer cases and other risk factors for breast cancer
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LaVigne, A., S. Grover, and S. Rayne. "Knowledge and Screening Practices of Breast and Cervical Cancer in Rural and Urban South Africa." Journal of Global Oncology 4, Supplement 2 (2018): 46s. http://dx.doi.org/10.1200/jgo.18.38000.

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Background: The South African government has recently released cancer policies for breast and cervical cancer—the most common types and causes of cancer-related death in South African women. Increased mortality rates and advanced disease at presentation in comparison with developed countries suggests a need for greater awareness of risk factors, screening and preventative methods individualized for the population at risk. Aim: To characterize and compare the knowledge base and perceptions of women in urban and rural settings, we assessed these factors in two different cohorts in South Africa.
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O’Neil, Daniel S., Wenlong Carl Chen, Oluwatosin Ayeni, et al. "Breast Cancer Care Quality in South Africa’s Public Health System: An Evaluation Using American Society of Clinical Oncology/National Quality Forum Measures." Journal of Global Oncology, no. 5 (December 2019): 1–16. http://dx.doi.org/10.1200/jgo.19.00171.

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PURPOSE The quality of breast cancer care in sub-Saharan Africa contributes to the region’s dismal breast cancer mortality. ASCO has issued quality measures focusing on delivery of adjuvant chemotherapy, radiotherapy, and endocrine therapy. We applied these measures in five South African public hospitals and analyzed factors associated with care concordance. MATERIALS AND METHODS Among 1,736 women with breast cancer who were enrolled in the South African Breast Cancer and HIV Outcomes study over 24 months, we evaluated care using ASCO’s three measures. We also evaluated adjuvant chemotherapy r
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Apffelstaedt, J., and K. Baatjes. "Breast cancer in emerging countries: The status of breast care in South Africa." European Journal of Cancer Supplements 6, no. 7 (2008): 167. http://dx.doi.org/10.1016/s1359-6349(08)70706-7.

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Roomaney, Rizwana, Ashraf Kagee, and Nina Knoll. "Received and perceived support subscales of the Berlin Social Support Scales in women diagnosed with breast cancer attending the breast clinic at Tygerberg hospital: structure and correlates." South African Journal of Psychology 50, no. 1 (2019): 54–66. http://dx.doi.org/10.1177/0081246319831819.

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Research in the field of psycho-oncology in South Africa is increasing, and there is a need for validated measures that assess factors associated with cancer, such as social support. The Berlin Social Support Scales are a battery of instruments that measure various types and functions of social support. The measure was originally developed for use among adult cancer patients, and their partners but has also been used among other clinical populations and healthy adults. We investigated the psychometric properties of the English version of the perceived and received sub-scales, Berlin Social Sup
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Ruffieux, Yann, Mazvita Muchengeti, Matthias Egger, et al. "Immunodeficiency and Cancer in 3.5 Million People Living With Human Immunodeficiency Virus (HIV): The South African HIV Cancer Match Study." Clinical Infectious Diseases 73, no. 3 (2021): e735-e744. http://dx.doi.org/10.1093/cid/ciab087.

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Abstract Background We analyzed associations between immunodeficiency and cancer incidence in a nationwide cohort of people living with human immunodeficiency virus (HIV; PLWH) in South Africa. Methods We used data from the South African HIV Cancer Match Study built on HIV-related laboratory measurements from the National Health Laboratory Services and cancer records from the National Cancer Registry. We evaluated associations between time-updated CD4 cell count and cancer incidence rates using Cox proportional hazards models. We reported adjusted hazard ratios (aHRs) over a grid of CD4 values
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Snyman, L. C. "Breast cancer mammography screening for low-risk women in South Africa." Southern African Journal of Gynaecological Oncology 2, no. 2 (2010): 69–70. http://dx.doi.org/10.1080/20742835.2010.11441164.

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19

Dickerson, Lindsay K., Anne F. Rositch, Susan Lucas, Lisa A. Mullen, and Susan C. Harvey. "An Educational Intervention and Feasibility Assessment of Breast Ultrasound in Rural South Africa." Journal of Global Oncology 4, Supplement 3 (2018): 14s. http://dx.doi.org/10.1200/jgo.18.10150.

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Purpose Breast cancer is the leading cause of cancer death in women worldwide, with a strikingly high mortality in low- and middle-income countries (LMICs) as a result of the scarcity of detection, diagnosis, and treatment. With mammography unavailable, ultrasound (US) offers a viable alternative. The literature reports successful training in various domains, but a curriculum focused on the breast is novel. We assessed the feasibility—knowledge acquisition, perceived utility, and self-efficacy—of a breast US training program for the detection of breast cancer by nonphysician providers. Methods
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Mbeje, Noluthando P., Themba G. Ginindza, and Nkosana Jafta. "Establishing and Evaluating Cancer Surveillance System in KwaZulu-Natal, South Africa." Cancer Informatics 20 (January 2021): 117693512110299. http://dx.doi.org/10.1177/11769351211029967.

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Background: The increasing cancer burden remains a public health challenge. Quality and accurate population data is important to improve cancer control, screening, and treatment programmes for the sub-Saharan Africa region. Aim: The aim of this study was to establish hospital-based cancer surveillance system, thereby reporting the burden that cancer diagnosis and treatment place on 3 hospitals – an approach of health systems strengthening. Methods: A hospital-based cancer surveillance was established in 3 public health facilities that provide oncology services in KwaZulu-Natal. An active metho
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Matatiele, PR, and WMJ Van den Heever. "Breast cancer profiles of women presenting with newly diagnosed breast cancer at Universitas Hospital (Bloemfontein, South Africa)." South African Family Practice 50, no. 6 (2008): 48–49. http://dx.doi.org/10.1080/20786204.2008.10873786.

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Langenhoven, Lizanne, Pieter Barnardt, Alfred I. Neugut, and Judith S. Jacobson. "Phenotype and Treatment of Breast Cancer in HIV-Positive and -Negative Women in Cape Town, South Africa." Journal of Global Oncology 2, no. 5 (2016): 284–91. http://dx.doi.org/10.1200/jgo.2015.002451.

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Purpose An estimated 5.9 million people in South Africa are infected with HIV. Because antiretroviral therapy has made infection with HIV a treatable, chronic condition, HIV-infected individuals are now surviving to middle and older age. We investigated the implications of HIV status for breast cancer in South Africa. Methods We compared clinical and demographic characteristics of women newly diagnosed with a first primary breast cancer at Tygerberg Hospital, Cape Town, South Africa, from January 2010 to December 2011 by HIV status. We then compared HIV-positive patients with HIV-negative cont
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Wadler, Brianna M., Christine M. Judge, Marianne Prout, Jennifer D. Allen, and Alan C. Geller. "Improving Breast Cancer Control via the Use of Community Health Workers in South Africa: A Critical Review." Journal of Oncology 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/150423.

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Breast cancer is a growing concern in low- and middle-income countries (LMCs). We explore community health worker (CHW) programs and describe their potential use in LMCs. We use South Africa as an example of how CHWs could improve access to breast health care because of its middle-income status, existing cancer centers, and history of CHW programs. CHWs could assume three main roles along the cancer control continuum: health education, screening, and patient navigation. By raising awareness about breast cancer through education, women are more likely to undergo screening. Many more women can b
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Rubin, Grace, Sarah Rayne, Naomi Lince-Deroche, et al. "Characterization and costs of breast conditions at an open access breast clinic in South Africa." Journal of Clinical Oncology 36, no. 15_suppl (2018): e13570-e13570. http://dx.doi.org/10.1200/jco.2018.36.15_suppl.e13570.

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Dickerson, Lindsay K., Anne F. Rositch, Susan Lucas, and Susan C. Harvey. "Pilot Educational Intervention and Feasibility Assessment of Breast Ultrasound in Rural South Africa." Journal of Global Oncology 3, no. 5 (2017): 502–8. http://dx.doi.org/10.1200/jgo.2016.008086.

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Purpose Breast cancer is the leading cause of cancer death in women worldwide, with high mortality in low- and middle-income countries because of a lack of detection, diagnosis, and treatment. With mammography unavailable, ultrasound offers an alternative for downstaging. The literature reports successful training in various domains, but a focus on the breast is novel. We assessed the feasibility (knowledge acquisition, perceived usefulness, and self-efficacy) of breast ultrasound training for nonphysician providers. Methods Training was implemented for 12 providers at Hlokomela Clinic in Hoed
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Cubasch, Herbert, Maureen Joffe, Rachel Hanisch, et al. "Breast cancer characteristics and HIV among 1,092 women in Soweto, South Africa." Breast Cancer Research and Treatment 140, no. 1 (2013): 177–86. http://dx.doi.org/10.1007/s10549-013-2606-y.

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Schoeman, Mardelle, Justus P. Apffelstaedt, Karin Baatjes, and Michael Urban. "Implementation of a breast cancer genetic service in South Africa – lessons learned." South African Medical Journal 103, no. 8 (2013): 529. http://dx.doi.org/10.7196/samj.6814.

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Moodley, J., F. M. Walter, S. E. Scott, and A. M. Mwaka. "Towards timely diagnosis of symptomatic breast and cervical cancer in South Africa." South African Medical Journal 108, no. 10 (2018): 803. http://dx.doi.org/10.7196/samj.2018.v108i10.13478.

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Kramer, Nicky, Jo Ramjith, and Delva Shamley. "Prevalence of shoulder morbidity after treatment for breast Cancer in South Africa." Supportive Care in Cancer 27, no. 7 (2018): 2591–98. http://dx.doi.org/10.1007/s00520-018-4540-3.

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Rayne, Sarah, Kathryn Schnippel, Cynthia Firnhaber, Kathryne Wright, Deirdre Kruger, and Carol-Ann Benn. "Fear of Treatments Surpasses Demographic and Socioeconomic Factors in Affecting Patients With Breast Cancer in Urban South Africa." Journal of Global Oncology 3, no. 2 (2017): 125–34. http://dx.doi.org/10.1200/jgo.2015.002691.

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Purpose Breast cancer is the most common cause of cancer in women in South Africa, and often patients present late. There is little understanding of the psychosocial stresses affecting women with breast cancer in Africa. Methods A questionnaire was distributed to 263 patients with breast cancer at two sites (one government and one private facility) in Johannesburg. Self-reported levels of fear were recorded on summative scales and their relationship to demographic variables assessed through univariable and multivariable modified Poisson regression. Results Fears related to treatments and progn
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Kriel, Inge, Kyara Bergstrom, and Carol Benn. "An assessment of supplement use in breast cancer patients from a single unit in South Africa." Journal of Clinical Oncology 36, no. 7_suppl (2018): 89. http://dx.doi.org/10.1200/jco.2018.36.7_suppl.89.

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89 Background: Breast cancer patients are particularly susceptible to marketing strategies employed to encourage the use of natural supplements and natural therapies. Supplements/natural therapies are freely available from various sources, including online commercial sites, therefore making them readily accessible and poorly regulated. Methods: An anonymous questionnaire on supplement use was distributed to patients diagnosed with breast cancer. Fifty-one questionnaires were completed and data was collected into a REDCapTM based database and subsequently analysed. Results: Thirty-two patients
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Cubasch, Herbert, Maureen Joffe, Paul Ruff, et al. "Breast conservation surgery versus total mastectomy among women with localized breast cancer in Soweto, South Africa." PLOS ONE 12, no. 8 (2017): e0182125. http://dx.doi.org/10.1371/journal.pone.0182125.

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Zwane, Duduzile. "“Our Beauty Is in Our Breasts”: A Culture-Centered Approach to Understanding Cancer Perceptions in Kwa Zulu Natal, South Africa." Qualitative Health Research 31, no. 1 (2020): 148–59. http://dx.doi.org/10.1177/1049732320960417.

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Breast cancer is an incapacitating physical illness. It was once reported predominantly by patients in developed countries. With the advent of globalization, it is increasingly becoming a major health concern in developing countries such as South Africa. Breast cancer researchers have continuously advocated for original studies that address this condition from a sociocultural perspective. Consequently, in this article I examine the perceptions of breast cancer patients from underprivileged parts of Kwa Zulu Natal (KZN). Thirty semi-structured interviews were conducted with Zulu women at a tert
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Joffe, Maureen, Oluwatosin Ayeni, Shane Anthony Norris, et al. "Barriers to early presentation of breast cancer among women in Soweto, South Africa." PLOS ONE 13, no. 2 (2018): e0192071. http://dx.doi.org/10.1371/journal.pone.0192071.

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Hadley, Megan E., Lisa A. Mullen, Lindsay Dickerson, and Susan C. Harvey. "Assessment and Improvement Strategies for a Breast Cancer Early Detection Program in Rural South Africa." Journal of Global Oncology 4, Supplement 3 (2018): 16s. http://dx.doi.org/10.1200/jgo.18.10180.

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Purpose More than one half of breast cancer deaths occur in low- and middle-income countries, where survival rates are 60% at best. Appropriate programs that improve detection, diagnosis, and treatment in low- and middle-income countries are essential to improving breast cancer outcomes. The sustainability of such programs requires ongoing efforts, yet there remains a lack of literature on follow-up to assure long-term program success. Our study aimed to understand what needs developed in the year after the implementation of an early detection program and to evaluate potential solutions. Metho
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Hadley, Megan, Lisa A. Mullen, Lindsay Dickerson, and Susan C. Harvey. "Assessment and Improvement Strategies for a Breast Cancer Early Detection Program in Rural South Africa." Journal of Global Oncology, no. 4 (December 2018): 1–12. http://dx.doi.org/10.1200/jgo.18.00015.

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Purpose To assess and develop solutions for an ultrasound-based breast cancer early detection program in rural South Africa 1 year after implementation. Methods A WHO-endorsed RAD-AID Radiology Readiness Assessment was used to evaluate clinic resources. In addition, 5 weeks of observation identified resource deficiencies and reviewed existing documentation methods. On the basis of stakeholders’ input and the BI-RADS, we developed new documentation systems. Training was followed by a survey that assessed feasibility and provider acceptance. Results Resource limitations included lack of computer
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Van Oers, HM. "Exercise effects on mood in breast cancer patients." South African Journal of Sports Medicine 25, no. 2 (2013): 55. http://dx.doi.org/10.17159/2078-516x/2013/v25i2a381.

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Breast cancer is one of the most common cancers worldwide, and statistics reveal that the number of women diagnosed with breast cancer in South Africa is increasing. As such, medical practitioners will treat an increasing number of breast cancer patients. Although increasingly effective treatments improve patient survival intervals, a significant number of patients experience psychological distress, at the time of diagnosis and sometimes well beyond the start of treatment. This can be attributed to the disease itself and to treatment side-effects. Historically, patients experiencing such distr
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Van Oers, HM. "Exercise effects on mood in breast cancer patients." South African Journal of Sports Medicine 25, no. 2 (2013): 55. http://dx.doi.org/10.17159/2413-3108/2013/v25i2a381.

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Breast cancer is one of the most common cancers worldwide, and statistics reveal that the number of women diagnosed with breast cancer in South Africa is increasing. As such, medical practitioners will treat an increasing number of breast cancer patients. Although increasingly effective treatments improve patient survival intervals, a significant number of patients experience psychological distress, at the time of diagnosis and sometimes well beyond the start of treatment. This can be attributed to the disease itself and to treatment side-effects. Historically, patients experiencing such distr
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Mzezewa, Salathiel Zhou, Musa Setati, Thendo Netshiongolwe, and Vusani Sinoamadi. "Prevalence of breast cancer in reduction mammoplasty specimens, in women of African origin: preliminary histology results at Mankweng and Polokwane hospitals." Journal of Medical Research and Health Sciences 3, no. 10 (2020): 1109–13. http://dx.doi.org/10.15520/jmrhs.v3i10.264.

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Abstract
 Introduction. We report the first study on the prevalence of breast cancer in reduction mammoplasty specimens conducted in Limpopo province, South Africa. The prevalence of breast cancer is relatively low among pre-menopausal African women. Worldwide prevalence has been reported to range between 0.1% and 4.5%. Patients requesting reduction mammoplasty fear that their breast enlargement may be caused by the disease. Reduction mammoplasty is a common operation performed by plastic and reconstructive surgeons globally, but is an uncommon operation in Limpopo.
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Lasebikan, N., N. Iloanusi, T. Onyeka, et al. "Tailoring Therapies: Improving the Outcome of Breast Cancer in a Comprehensive Cancer Center in West Africa—The University of Nigeria Teaching Hospital Experience." Journal of Global Oncology 4, Supplement 2 (2018): 163s. http://dx.doi.org/10.1200/jgo.18.73100.

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Background and context: Early detection and improved treatments are associated with a reduction in breast cancer mortality and morbidity. UNTH is a leading comprehensive cancer center in Nigeria with referrals from the entire southeast and south south regions. Our goal is to offer high quality comprehensive cancer care services across the cancer care continuum from public health awareness campaigns and provision of screening services all the way to palliative care and survivorship. This is the first attempt by any institution in the country to standardize and harmonize available treatment opti
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Dickens, Caroline, Ruth M. Pfeiffer, William F. Anderson, et al. "Investigation of breast cancer sub-populations in black and white women in South Africa." Breast Cancer Research and Treatment 160, no. 3 (2016): 531–37. http://dx.doi.org/10.1007/s10549-016-4019-1.

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Rayne, Sarah, Kathryn Schnippel, Carol Benn, Deirdre Kruger, Kathryne Wright, and Cynthia Firnhaber. "The Effect of Access to Information on Beliefs Surrounding Breast Cancer in South Africa." Journal of Cancer Education 33, no. 4 (2017): 806–13. http://dx.doi.org/10.1007/s13187-017-1234-3.

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Nietz, Sarah, Paul Ruff, Wenlong Carl Chen, Daniel S. O’Neil, and Shane A. Norris. "Quality indicators for the diagnosis and surgical management of breast cancer in South Africa." Breast 54 (December 2020): 187–96. http://dx.doi.org/10.1016/j.breast.2020.09.012.

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44

Eyigör, Sibel. "Comments on “Prevalence of shoulder morbidity after treatment for breast Cancer in South Africa”." Supportive Care in Cancer 28, no. 3 (2019): 959–60. http://dx.doi.org/10.1007/s00520-019-04990-z.

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45

Kamaraju, Sailaja, Jeffrey Drope, Rengaswamy Sankaranarayanan, and Surendra Shastri. "Cancer Prevention in Low-Resource Countries: An Overview of the Opportunity." American Society of Clinical Oncology Educational Book, no. 40 (May 2020): 72–83. http://dx.doi.org/10.1200/edbk_280625.

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Rising trends in the incidence of cancer in low- and middle-income countries (LMICs) add to the existing challenges with communicable and noncommunicable diseases. While breast and colorectal cancer incidence rates are increasing in LMICs, the incidence of cervical cancer shows a mixed trend, with rising incidence rates in China and sub-Saharan Africa and declining trends in the Indian subcontinent and South America. The increasing frequencies of unhealthy lifestyles, notably less physical activity, obesity, tobacco use, and alcohol consumption are causing a threat to health care in LMICs. Als
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Donninger, Howard, David M. Dent, and M. Iqbal Parker. "Infrequent and Unusual p53 Mutations in Breast Cancers in South Africa." Genome Letters 1, no. 4 (2002): 157–64. http://dx.doi.org/10.1166/gl.2002.018.

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Langa, Bridget C., Márcia M. C. Oliveira, Silma R. F. Pereira, et al. "Copy Number Analysis of the DLX4 and ERBB2 Genes in South African Breast Cancer Patients." Cytogenetic and Genome Research 146, no. 3 (2015): 195–203. http://dx.doi.org/10.1159/000439155.

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Breast cancer is one of the main causes of cancer death among South African women. Although several risk factors can be attributed to the observed high mortality rate, the biology of the tumors is not extensively investigated. Copy number gain of the DLX4 homeobox gene has been observed in breast cancer in association with poor prognosis and specific racial groups. Therefore, we aimed to assess the copy number and prognostic role of DLX4 in breast cancer from South African patients. Due to the co-location of ERBB2 and DLX4 in the 17q21 region, its copy number was also evaluated. Our results in
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Peltzer, Karl, and Nancy Phaswana-Mafuya. "Breast and Cervical Cancer Screening and Associated Factors among Older Adult Women in South Africa." Asian Pacific Journal of Cancer Prevention 15, no. 6 (2014): 2473–76. http://dx.doi.org/10.7314/apjcp.2014.15.6.2473.

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Matatiele, PR, and WMJ Van den Heever. "Evaluation of breast cancer awareness among women presenting with newly diagnosed breast disease at Universitas Hospital (Bloemfontein, South Africa)." South African Family Practice 50, no. 4 (2008): 69–69. http://dx.doi.org/10.1080/20786204.2008.10873745.

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Rayne, Sarah, Kathryn Schnippel, John Thomson, Joanna Reid, and Carol Benn. "Male Breast Cancer Has Limited Effect on Survivor’s Perceptions of Their Own Masculinity." American Journal of Men's Health 11, no. 2 (2016): 246–52. http://dx.doi.org/10.1177/1557988316631512.

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The purpose of the current study was to describe male breast cancer in Johannesburg, South Africa, and assess whether male breast cancer patients’ perception of their own masculinity was affected by having a cancer commonly seen in women. A retrospective file review was carried out at two hospitals, one private and one government, of male breast cancer patients from 2007 to 2012 followed by a telephone survey of patients identified during review. Of approximately 3,000 breast cancer patients seen in the 5 years reviewed, 23 cases of male breast cancer were identified. Most were diagnosed with
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