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1

Lotter, Luisa, Isabel Zucal, Vanessa Brébant, et al. "Intraoperative 3D Comparison of Round and Anatomical Breast Implants: Dispelling a Myth." Journal of Clinical Medicine 11, no. 1 (2021): 149. http://dx.doi.org/10.3390/jcm11010149.

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Background: Thanks to 3D imaging, it is possible to measure the influence of different parameters on breast augmentation. In this study, we compare the effect of different shapes and sizes of breast implants on the topography of the resulting breast. Furthermore, the impact of different breast implants on inter-landmark distances and on changes of the nipple position was assessed. Methods: This interventional prospective study was carried out on 10 female patients after collecting informed consent. 3D scans of the native and augmented breasts were performed intraoperatively with small, medium,
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Magno-Padron, David A., Jessica Luo, Terry C. Jessop, et al. "A population-based study of breast implant illness." Archives of Plastic Surgery 48, no. 4 (2021): 353–60. http://dx.doi.org/10.5999/aps.2020.02117.

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Background Despite evidence supporting the safety of breast implants, some women associate their implants with adverse health effects and have called this syndrome “breast implant illness.” We sought to characterize breast implant illness symptoms and to report how implant removal affects their symptoms.Methods An anonymous 20 question survey was administered to the Facebook group: “UTAH Breast Implant Illness” to characterize the symptoms these women attributed to their breast implants. Several questions allowed us to evaluate how implant removal affected women’s symptoms.Results Of the 182 r
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Lee, Joo Hyuck, Jae Hyuk Jang, and Kyung Hee Min. "A Comparison of Smooth and Microtextured Breast Implants in Breast Augmentation: A Retrospective Study." Archives of Plastic Surgery 50, no. 02 (2023): 160–65. http://dx.doi.org/10.1055/s-0042-1760405.

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Abstract Background The number of cosmetic and reconstructive surgeries that use breast implants is increasing in Korea. Recently, it has been reported that breast implant-associated anaplastic large-cell lymphoma is related to textured breast implants, and interest in classification according to the texture of breast implants is increasing. However, there is currently no clear and unified classification. In particular, the definition of “microtextured” is highly varied. In this study, we retrospectively investigated and analyzed the clinical outcomes of smooth and microtextured breast implant
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Varela-Chinchilla, Carlos Daniel, Gabriel Salinas-McQuary, Nancy de los Ángeles Segura-Azuara, and Plinio A. Trinidad-Calderón. "Breast Implant Illness: Surgical, Autoimmune, and Breast Reconstruction Associations." Surgeries 3, no. 2 (2022): 111–25. http://dx.doi.org/10.3390/surgeries3020013.

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Breast implant illness refers to a combination of different symptoms related to breast implant surgery, including fatigue, brain fog, and arthralgias. This malaise occurs after cosmetic and reconstructive breast surgeries, although it has not been proven to be a disease. Even recent studies have reported concluding statements of the etiology, diagnosis, and treatment as unclear and widely unknown. Therefore, this review aimed to determine the associations between the manifestations of breast implant illness in surgery and breast reconstruction, as well as the autoimmune responses involved. Com
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Lieffering, Annemiek S., Juliëtte E. Hommes, Lotte Ramerman, et al. "Prevalence of Local Postoperative Complications and Breast Implant Illness in Women With Breast Implants." JAMA Network Open 5, no. 10 (2022): e2236519. http://dx.doi.org/10.1001/jamanetworkopen.2022.36519.

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ImportanceIt is unknown how often breast implant illness (BII) is the indication for revision in women with silicone breast implants.ObjectiveTo examine how often women with silicone breast implants have their implants explanted or replaced because of BII compared with local postoperative complications.Design, Setting, and ParticipantsA legacy cohort study on breast implant revision surgery was conducted between April 1, 2015, and December 31, 2020, and a prospective cohort study on breast implantation and revision surgery was conducted between April 1, 2015, and December 31, 2019 (with follow
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Qaiser, Fatima, Hina Pathan, Ahmed Raza, and Anam Khan. "From cosmetic to critical: breast implant rupture revealing invasive lobular breast carcinoma." BMJ Case Reports 18, no. 6 (2025): e265546. https://doi.org/10.1136/bcr-2025-265546.

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Over the past 20 years, breast augmentation has become increasingly popular for enhancing breast size and correcting asymmetry. Saline implants were initially used, followed by silicone implants and autologous fat transfer. However, complications such as infection, implant failure and capsular contracture are common, while rare cases of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) exist.A woman in her 60s with no breast cancer risk factors underwent bilateral augmentation mammoplasty. Her preoperative imaging was unremarkable, and she was advised to regular follow-up but
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Mude, Madhusudana Naik. "Breast implant rupture: removal and re-implantation: a dual case report." International Surgery Journal 12, no. 2 (2025): 218–21. https://doi.org/10.18203/2349-2902.isj20250150.

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Breast implant surgery is now among the top five plastic surgeries done for cosmetic purpose globally. Silicone implants are the most common type of implants used whereas saline implants are used by very few. In the long run, rupture of the breast implant is a complication of these kind of surgeries. As per one study, over a period of 3-20 years, the silicone implants are likely to rupture. After three years of the breast implant surgery, it has been estimated that the survival rate for the silicone breast implants is around 83-85%. Some implant ruptures are silent or asymptomatic. Early diagn
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Flores, Tonatiuh, Celina Kerschbaumer, Christina Glisic, Michael Weber, Klaus F. Schrögendorfer, and Konstantin D. Bergmeister. "Breast Implants: Low Rate of Annual Check-Ups Results in Delayed Presentation of Ruptured Implants." Journal of Clinical Medicine 13, no. 21 (2024): 6545. http://dx.doi.org/10.3390/jcm13216545.

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Background: Breast-implant-based reconstruction is one of the most performed procedures in plastic surgery. Despite the high durability of breast implants, various complications are accompanied with prolonged inlay duration, particularly implant rupture. Many aftereffects can be associated with implant rupture, especially siliconoma and BIA-ALCL. Without regular implant check-ups, implant-related issues may remain underrecognized. Here, we analyzed the number of breast implant carriers needing revisions and if patients adhered to annual implant follow-up recommendations. Methods: We reviewed 1
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Brandon, Harold J., Larry S. Nichter, and Dwight D. Back. "New Evaluation Procedure for Multi-Dimensional Mechanical Strains and Tangent Moduli of Breast Implants: IDEAL IMPLANT® Structured Breast Implant Compared to Silicone Gel Implants." Bioengineering 6, no. 2 (2019): 43. http://dx.doi.org/10.3390/bioengineering6020043.

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The IDEAL IMPLANT® Structured Breast Implant is a dual lumen saline-filled implant with capsular contracture and deflation/rupture rates much lower than single-lumen silicone gel-filled implants. To better understand the implant’s mechanical properties and to provide a potential explanation for these eight-year clinical results, a novel approach to compressive load testing was employed. Multi-dimensional strains and tangent moduli, metrics describing the shape stability of the total implant, were derived from the experimental load and platen spacing data. The IDEAL IMPLANT was found to have pr
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Jovic, Marko, Ivan Radosavljevic, Jovan Mihaljevic, Jelena Jeremic, and Milan Jovanovic. "Breast implant rupture 37 years after breast augmentation." Srpski arhiv za celokupno lekarstvo, no. 00 (2021): 69. http://dx.doi.org/10.2298/sarh210401069j.

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Introduction Silicone implants have been used ever since the second half of the 20th century. Over that period several generations of implants have been developed that differed in thickness of the shell and viscosity of the silicone gel. Development of these generations of implants was accompanied with different complication rates. The first-generation implants had the lowest tendency to rupture, but were more prone to capsular contracture and calcification formation. Case outline An 81-year-old female patient had her silicone implants placed in 1983. After a chest injury in 2015. on the later
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Francisco, Javier De la Rosa Burciaga, Adrián Salas Rivas Héctor, Gandhi García Preza Luis, Fabián Vidales Cervantes Axel, and David Nava Gómez Luis. "Breast Implant Rupture: Causes, Diagnosis and Treatment." International Journal Of Medical Science And Clinical Research Studies 03, no. 05 (2023): 857–60. https://doi.org/10.5281/zenodo.7907003.

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Breast implant rupture is a rare event that can occur at any time after breast augmentation surgery. The most common causes of rupture are natural aging of the implant, traumatic injury, and failure of the implant material. Symptoms of breast implant rupture can range from mild discomfort to total loss of breast shape and size.   Diagnosing a ruptured breast implant can be challenging, as the condition can be asymptomatic in some cases. However, imaging tests such as MRI and ultrasound can help detect the presence of ruptured implants. Treatment options for ruptured breast implants vary d
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Kim, Yang-Hee, Dong-Wook Park, Keun-Yeong Song, Hyung-Guhn Lim, Jeong-Pil Jeong, and Jae-Hong Kim. "Use of High-Resolution Ultrasound in Characterizing the Surface Topography of a Breast Implant." Medicina 59, no. 6 (2023): 1092. http://dx.doi.org/10.3390/medicina59061092.

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Background and Objectives: With the emergence of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), it has become necessary to identify the implant shell type patients have received. Therefore, an immediate, reliable method for identifying a breast implant shell type is essential. Evidence-based research and applying a real-world technique that identifies the surface topographic information of the inserted breast implants, without surgery, has become of paramount importance for breast implant physicians. Methods and Materials: A review of the medical records of 1901 patients
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Peters, Walter. "The Evolution of Breast Implants." Canadian Journal of Plastic Surgery 10, no. 5 (2002): 223–36. http://dx.doi.org/10.1177/229255030201000508.

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The present review traces the evolution of breast implants over the past 50 years. During the early years (from 1951 to 1962), a number of different sponges were used for breast augmentation. The first of these was Ivalon, a polyvinyl alcohol sponge. Other sponges were introduced subsequently, including Etheron (a poly-ether sponge popularized by Dr Paule Regnault in Montreal) and Polystan (fabric tapes that were wound into a ball). Subsequently, polyethylene strips enclosed in a fabric or polyethylene casing were also used for breast augmentation. All of these materials had similar outcomes.
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Wood, Dallas, Peyton N. Williams, Jessica E. Thompson, et al. "A Threshold Technique Study to Understand Patient Preference for Smooth Versus Textured Breast Implants." Plastic and Reconstructive Surgery - Global Open 13, no. 1 (2025): e6362. https://doi.org/10.1097/gox.0000000000006362.

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Background: Breast implant surfaces are categorized as smooth or textured. Compared with smooth implants, textured surface implants have a higher risk of breast implant–associated anaplastic large cell lymphoma (BIA-ALCL) but may have a lower risk of capsular contracture (CC). This study aimed to quantify whether survey respondents would be willing to accept a higher risk of BIA-ALCL in exchange for the potential reported benefits of textured breast implants. Methods: We fielded a threshold technique survey to 405 respondents from 4 cohorts: (1) patients with breast cancer who were considering
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Cala Uribe, Laura C., Mauricio Perez Pachon, Andres Villate Hernandez, and Andreina Zannin Ferrero. "Kite Mastopexy: Small Scar and Tissue-conserving Technique." Plastic and Reconstructive Surgery - Global Open 11, no. 9 (2023): e5265. http://dx.doi.org/10.1097/gox.0000000000005265.

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Background: Breasts are considered one of the most physically and sexually appealing features of the female body. Reduction/augmentation techniques have greatly evolved in the last decades. We are reporting our experience with an innovative technique for mastopexy that recovers the aesthetics of the breast and avoids over-resection of its lower pole. Methods: Inclusion criteria were women who underwent kite mastopexy with or without implants between January 2018 and May 2022 in a single center (Bogota, Colombia). Exclusion criteria were patients with American Society of Anesthesiology score mo
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Eisenberg, Ted. "One-Stage Correction of Tuberous Breast Deformity Using Saline Implants: Without the Need for Radial Scoring or Lowering the Inframammary Fold." American Journal of Cosmetic Surgery 36, no. 4 (2019): 191–96. http://dx.doi.org/10.1177/0748806819841466.

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Tuberous breasts are a congenital anomaly in which the breasts fail to develop normally. This abnormality may include hypoplasia, a tubular appearance, a higher inframammary fold (IMF), and sometimes a herniated nipple-areolar complex. Correction of tuberous breast deformity (TBD) is traditionally done with a 1-stage breast augmentation with radial scoring of the constricted breast tissue and/or the lowering of the IMF. An alternative 2-stage approach first uses a tissue expander to correct the deformity; the expander is later replaced with a permanent breast implant. Sixteen patients are pres
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Leduey, Alexandre, Chafika Mazouni, Nicolas Leymarie, et al. "Comparison of the Explantation Rate of Poly Implant Prothèse, Allergan, and Pérouse Silicone Breast Implants within the First Four Years after Reconstructive Surgery before the Poly Implant Prothèse Alert by the French Regulatory Authority." International Journal of Breast Cancer 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/519497.

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Background. In March 2010, ANSM (Agence Nationale de Sécurité du Medicament), the French Medical Regulatory Authority, withdrew Poly Implant Prothèse (PIP) breast implants from the market due to the use of non-medical-grade silicone gel. The aim of this study was to compare the removal rate (and reasons thereof) of breast implants produced by different manufacturers before the ANSM alert.Materials and Methods. From October 2006 to January 2010, 652 women received 944 implants after breast cancer surgery at the Gustave Roussy Comprehensive Cancer Center, Paris (France). The complications and re
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Azahaf, Siham, Karlinde A. Spit, Christel J. M. de Blok, Peter Bult, and Prabath W. B. Nanayakkara. "Silicone Migration from Intact Saline Breast Implants." Plastic and Reconstructive Surgery - Global Open 12, no. 2 (2024): e5608. http://dx.doi.org/10.1097/gox.0000000000005608.

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Summary: Breast augmentation is a widely performed surgical procedure worldwide, predominantly using silicone gel-filled implants. Concerns have primarily revolved around ruptures and the potential health risks associated with leaked silicone from silicone gel-filled implants. Cases of silicone migration from the shell of saline breast implants remain scarce. This case report introduces a unique case of a 66-year-old patient with silicone migration from intact saline breast implants. The patient presented with a range of symptoms consistent with breast implant illness. Radiological findings su
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Rukanskienė, Dalia, Greta Bytautaitė, Agnė Česnauskaitė, Loreta Pilipaitytė, Tautrimas Aštrauskas, and Eglė Jonaitienė. "The Value of Ultrasound in the Evaluation of the Integrity of Silicone Breast Implants." Medicina 57, no. 5 (2021): 440. http://dx.doi.org/10.3390/medicina57050440.

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Background and Objective: Breast implant surgery for cosmetic purposes is the most popular plastic surgery and it has been performed for over 100 years. Rupture of silicone gel-filled breast implants usually is asymptomatic and is one of the more dangerous complications due to free silicone migration. The aim of our study was to evaluate the diagnostic value of ultrasound (US) in the evaluation of the integrity of silicone breast implants and identify the main sign of intact and ruptured breast implants. Patients and Methods: In this retrospective study, the medical documentation of women who
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Jaeger, Marie, Charles Randquist, and Jessica Gahm. "Anatomical Breast Implant Assessment Using Ultrasound: A Case Series from the International Breast Implant Check Clinic." Plastic and Reconstructive Surgery - Global Open 11, no. 12 (2023): e5469. http://dx.doi.org/10.1097/gox.0000000000005469.

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Background: Breast augmentation with anatomic implants can achieve a natural look, but over time, implant-related complications can occur. This includes a risk of potential rotation, which can cause a change in breast shape. Reported rates of rotation vary widely (0%–42%). Implant rotation is often detected by physical examination only or as a perioperative finding. Change in breast shape after augmentation requires clinical evaluation. In-office ultrasound allows for detailed assessment of implants for rotation and other complications. Methods: Women with anatomical breast implants seeking fo
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Peters, Walter. "Current Status of Breast Implant Survival Properties and the Management of the Woman with Silicone Gel Breast Implants." Canadian Journal of Plastic Surgery 8, no. 2 (2000): 54–67. http://dx.doi.org/10.1177/229255030000800201.

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The survival properties of silicone gel breast implants are dependent on their vintage (year of manufacture), duration in situ and manufacturer. A total of 527 gel implants have been explanted and analyzed in the author's laboratories. Of the 28 first-generation implants (1963 to 1972), 27 (96.4%) remained intact after 14 to 28 years in situ (mean 20.8 years). Of the 216 second-generation implants (1973 to mid-1980s) that were explanted from 1992 to 1998, 158 (73%) had disrupted. Kaplan-Meier survival curves demonstrated significantly different survival properties among second-generation manuf
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Nichter, Larry S., Robert A. Hardesty, and Gregg M. Anigian. "IDEAL IMPLANT Structured Breast Implants." Plastic and Reconstructive Surgery 142, no. 1 (2018): 66–75. http://dx.doi.org/10.1097/prs.0000000000004460.

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Nam, Sun-Young, Han Bi Ji, Byung Ho Shin, et al. "Silicone Breast Implant Coated with Triamcinolone Inhibited Breast-Implant-Induced Fibrosis in a Porcine Model." Materials 14, no. 14 (2021): 3917. http://dx.doi.org/10.3390/ma14143917.

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Cosmetic silicone implants for breast reconstruction often lead to medical complications, such as abnormally excessive fibrosis driven by foreign body granulomatous inflammation. The purpose of this study was to develop a silicone breast implant capable of local and controlled release of a glucocorticoid drug triamcinolone acetonide (TA) for the prevention of silicone-breast-implant-induced fibrosis in a Yorkshire pig model (in vivo). Implants were dip-coated in a TA solution to load 1.85 μg/cm2 of TA in the implant shell, which could release the drug in a sustained manner for over 50 days. Im
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Sharobaro, V. I., G. E. Karepetyan, O. A. Kononets, D. K. Rozova, and S. A. Burdin. "Correction of problems associated with breast implants." Plastic Surgery and Aesthetic Medicine, no. 1 (March 5, 2025): 116. https://doi.org/10.17116/plast.hirurgia2025011116.

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Objective. To review available data on complications associated with silicone breast implants, as well as methods of their prevention and correction. Material and methods. The PubMed, Google Scholar, Scopus, Cochrane, eLibrary databases were reviewed. The following keywords were used: “complications of breast enlargement”, “capsular contracture”, “double bubble breast deformity”, “waterfall breast deformity”, “implant rippling”, “breast implant palpability”, “implant malposition”, “symmastia”, “implant visibility”. After reading the abstracts, full-text Russian- and English-language articles p
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Jari, Irina, Alexandru G. Naum, Liliana Gheorghe, et al. "Granuloma of Silicone Breast Implants A case report and literature review." Revista de Chimie 70, no. 3 (2019): 940–42. http://dx.doi.org/10.37358/rc.19.3.7035.

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Silicone, a synthetic polymer containing the element silicon, has been used for breast implants. Complications resulting from the placement of silicone breast implants are becoming more frequent in clinical practice. Breast implant rupture is common and poses challenges for radiologists and physicians. Radiologists must be familiar with the normal and abnormal findings of common implants. Clinically apparent silicone granulomas are a relatively rare complication of breast implant placement and surgical resection is indicated when they are symptomatic or of diagnostic concern. The objective of
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Eveline, Kezia, Beta Subakti Nata'admadja, Rizqi Shabrina Lestari, and Lavonia Berlina Adzalika. "SYSTEMATIC REVIEW: ANAPLASTIC LARGE CELL LYMPHOMA FOLLOWING BREAST IMPLANT SURGERY." Jurnal Rekonstruksi dan Estetik 8, no. 1 (2023): 47–58. http://dx.doi.org/10.20473/jre.v8i1.31215.

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Highlights: BIA-ALCL, a T-cell lymphoma associated with breast implants, is posing a growing medical challenge due to the increasing use of implants for cosmetic and reconstructive purposes The majority of BIA-ALCL cases were associated with cosmetic reasons for breast implants, and textured implants were predominantly implicated. Abstract: Introduction: BIA-ALCL, a T-cell lymphoma associated with breast implants, poses a growing medical challenge despite its relatively low occurrence, due to the increasing use of implants for cosmetic and reconstructive purposes. Our objective is to review th
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Peters, Walter. "Current status of silicone gel breast implants." Canadian Journal of Plastic Surgery 2, no. 1 (1994): 18–23. http://dx.doi.org/10.1177/229255039400200103.

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There are currently three main areas of concern regarding the safety of silicone gel implants: implant failure; a potential link to autoimmune connective tissue disease; and a possible link to breast cancer. All silicone gel implants ‘bleed’ small levels of silicone. In addition, silicone gel implants appear to fail (leak or rupture) with time. Most implants in place for less than seven years appear to be intact. It appears that many silicone gel implants implanted for over seven years are probably ruptured or leaking. Implant failure may occur simply from deterioration. Implants can also rupt
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Khan, Umar D. "Relative Distribution of Common Breast and Chest Asymmetries in 2051 Primary Augmentation Mammoplasties in Nonptotic Subgroup of Patients." Plastic and Reconstructive Surgery - Global Open 12, no. 8 (2024): e6016. http://dx.doi.org/10.1097/gox.0000000000006016.

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Background: Breast and chest asymmetries are extremely common, and primary augmentation mammoplasty can be challenging in these cases. However, there is a paucity of information on the relative distribution of these asymmetries and the implant sizes used in these patients. Methods: A retrospective chart review of all consecutive cases of primary augmentation mammoplasty performed by a single surgeon from May 1999 to May 2012 was conducted. Patients with chest and breast asymmetries were noted by clinical examination and observation. These patients were selected to review how many patients had
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Carmona-Torre, Francisco, Leire Fernández-Ciriza, Carlos Berniz, et al. "An Experimental Murine Model to Assess Biofilm Persistence on Commercial Breast Implant Surfaces." Microorganisms 10, no. 10 (2022): 2004. http://dx.doi.org/10.3390/microorganisms10102004.

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Capsular contracture is the most frequently associated complication following breast implant placement. Biofilm formation on the surface of such implants could significantly influence the pathogenesis of this complication. The objective of this study was to design an experimental model of breast implant infection that allowed us to compare the in vivo S. epidermidis ability to form and perpetuate biofilms on commonly used types of breast implants (i.e., macrotexturized, microtexturized, and smooth). A biofilm forming S. epidermidis strain (ATCC 35984) was used for all experiments. Three differ
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Norris, Michelle, Melissa Jones, Chris Mills, Tim Blackmore, Chris Inglefield, and Joanna Wakefield-Scurr. "The Kinematics of Breasts Implanted With a Reduced Mass Implant: A Pilot Study." Aesthetic Surgery Journal 40, no. 5 (2019): NP253—NP262. http://dx.doi.org/10.1093/asj/sjz239.

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Abstract Background Breast implants may increase breast skin tension and interact with surrounding tissues to alter breast position and motion during dynamic activity. Reducing implant mass and changing implant location (submuscular/subglandular) may also affect breast kinematics and the subsequent loads on breast structures. Objectives The aim of this pilot study was to describe the kinematics of breasts augmented with reduced-mass implants during standing, walking, and running, compared with natural breasts, and to provide insight into how implant location (submuscular/subglandular) alters b
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Mishalov, V. G., О. І. Zakhartseva, V. V. Khrapach, and L. Yu Markulan. "SURGICAL TREATMENT OF BREAST IMPLANTS ROTATION." Medical Science of Ukraine (MSU) 13, no. 3-4 (2018): 10–14. http://dx.doi.org/10.32345/2664-4738.3-4.2017.02.

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Relevance. Using anatomical breast implants with high and ultrahigh profile in augmentation mammoplasty provides nearly natural shape of breasts. Using the drop-like shape implants instead of round ones can cause complication called breast implant rotation (BIR), that have negative influence on patients life quality. There is not enough data about the effective methods of surgical treatment of clinically significant rotation.
 Objective of our study was to determine the effectiveness of «neo pocket» upper pole inhancement with mesh for the treatment of BIR after primary submuscular breast
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Spit, K. A., S. Azahaf, C. J. M. de Blok, and P. W. B. Nanayakkara. "Measuring Platinum Levels in Hair in Women with Silicone Breast Implants and Systemic Symptoms." Plastic and Reconstructive Surgery - Global Open 10, no. 6 (2022): e4373. http://dx.doi.org/10.1097/gox.0000000000004373.

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Background: It has been suggested that compounds present in silicone breast implants (eg, silicone particles or heavy metals such as platinum) migrate into the body and can cause systemic symptoms in susceptible women, causing what is known as breast implant illness. This pilot study investigates possible associations between hair platinum levels in patients with breast implants and breast implant illness, and evaluates its possible use for diagnostic purposes. Methods: Patients were included from the silicone outpatient clinic at Amsterdam University Medical Centre. Platinum concentration in
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Shiffman, Melvin A. "Manufacture of Silicone Implants." American Journal of Cosmetic Surgery 13, no. 3 (1996): 191–97. http://dx.doi.org/10.1177/074880689601300302.

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Research and development of breast implant manufacturing technology continues with the dual objectives of finding better processes for manufacturing implant shells and finding better filler solutions or gels. The Mentor HIS manufacturing process exemplifies improved techniques of implant shell production and quality control. The process is described in detail, and the Mentor HIS and McGhan processes of manufacturing breast implants are compared. Recognized shell weaknesses include thin spots, valve malfunction, rupture because of overfilling, and folding and leakage because of underfilling. Al
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Pannucci, Christopher J., Chad K. Wheeler, Krista M. Cyr, and Adam J. Cyr. "Breast Implants Decrease Chest Wall Trauma in Low-speed, Unrestrained Motor Vehicle Crash: An Experimental Model." Plastic and Reconstructive Surgery - Global Open 11, no. 7 (2023): e5161. http://dx.doi.org/10.1097/gox.0000000000005161.

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Introduction: Breast implants improve quality of life in patients seeking improved breast aesthetics, and are known to minimize human injury in the less common scenario of penetrating trauma. People commonly sustain rib and sternum fractures and thoracic injury in motor vehicle crashes (MVC), a form of blunt traumatic injury. Whether breast implants minimize injury during MVC is unknown. This study examines the potential protective effect of breast implants in low speed, unrestrained MVC. Methods: Control (medical gel) and implant (medical gel with embedded breast implant) blocks were subjecte
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Hanna, Rami, Udi Maor, Meir Retchkiman, Basel Abu-Ganem, Julie Vaynshtein, and Eldad Silberstein. "Truth or Myth: Is Breast Implant Illness Really an Illness?" Plastic and Reconstructive Surgery - Global Open 13, no. 6 (2025): e6881. https://doi.org/10.1097/gox.0000000000006881.

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Background: Breast implant illness (BII) represents symptoms linked to silicone gel–filled breast implants. Research on BII remains limited, yielding contradictory conclusions. This study compared symptoms among healthy women with breast implants to those without breast implants. Methods: A single-blind questionnaire-based survey of asymptomatic female patients attending cancer screening was conducted at the Breast Health Center in Soroka Medical Center and at a breast surgeon’s community clinic in Beer Sheva, Israel. The study included women with breast implants (implanted group) and those wi
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Lee, Won-Seob, Tae-Gon Kim, Jun-Ho Lee, and Il-Kug Kim. "Breast Reconstruction after Breast Implant-Associated Anaplastic Large Cell Lymphoma Treatment: A Case Report and Literature Review." Journal of Clinical Medicine 12, no. 5 (2023): 1885. http://dx.doi.org/10.3390/jcm12051885.

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Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a T-cell non-Hodgkin’s lymphoma that occurs in patients with at least one prior textured breast implant. BIA-ALCL has a relatively good prognosis when treated promptly. However, data on the methods and timing of the reconstruction process are lacking. Herein, we report the first case of BIA-ALCL in Republic of Korea in a patient who underwent breast reconstruction using implants and an acellular dermal matrix (ADM). A 47-year-old female patient was diagnosed with BIA-ALCL stage IIA (T4N0M0) and underwent bilateral breast au
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Aladari, Nadia, Madalina M. Palaghia, Ana-Maria Trofin, et al. "Reducing Capsular Contracture Formation in Breast Augmentation with Silicone Implants: Experimental Study on Rats." Applied Sciences 12, no. 8 (2022): 4056. http://dx.doi.org/10.3390/app12084056.

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Silicone implants are frequently used for breast augmentation and reconstruction. However, late complication, such as capsular contracture, remain the most important side effect. In this study we compare different methods for reducing the inflammatory reaction around the silicone implant by introducing one microtextured breast implant in wistar rats. The rats were dividing in 4 groups: the first one was the control group that received untreated implant; in the second we used silicone implants impregnated with rifampin solution, the third one had implant combined with intramuscular dexamethason
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38

Lista, Frank, Ryan E. Austin, Maryam Saheb-Al-Zamani, and Jamil Ahmad. "Does Implant Surface Texture Affect the Risk of Capsular Contracture in Subglandular Breast Augmentation and Breast Augmentation-Mastopexy?" Aesthetic Surgery Journal 40, no. 5 (2019): 499–512. http://dx.doi.org/10.1093/asj/sjz241.

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Abstract Background Previous studies have reported decreased rates of capsular contracture associated with the use of textured surface breast implants placed in the subglandular plane during breast augmentation. However, since the publication of these studies, our understanding of the pathophysiology of capsular contracture, as well as the surgical techniques utilized to minimize bacterial contamination of the implant, have advanced considerably. Objectives The purpose of this study was to re-evaluate the relation between implant surface texturization and capsular contracture rates for breast
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39

Hecker, Andrzej, Barbara Giese, Anna-Lisa Pignet, Marlies Schellnegger, Lars-Peter Kamolz, and David Benjamin Lumenta. "Textured vs. Smooth Breast Implants Using the Jones Criteria—What Is the Currently Available Evidence for BIA-ALCL?: A Systematic Review." Journal of Personalized Medicine 13, no. 5 (2023): 816. http://dx.doi.org/10.3390/jpm13050816.

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Breast-Implant-Associated Anaplastic Large-Cell Lymphoma (BIA-ALCL) is a rare low-incidence type of T-cell non-Hodgkin lymphoma, arising in the capsule around breast implants, and predominantly associated with the use of macro-textured breast implants. The purpose of this study was to use an evidence-based approach to systematically identify clinical studies comparing smooth and textured breast implants in women with regard to the risk of developing BIA-ALCL. Methods: A literature search in PubMed in April 2023 and the article reference list of the French National Agency of Medicine and Health
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Robinson, Kristin A., Richard J. Gray, Aneri Tanna, et al. "Patient-Awareness Survey: Do Breast Implants Affect the Acquisition and Accuracy of Screening Mammography?" Journal of Breast Imaging 1, no. 4 (2019): 297–302. http://dx.doi.org/10.1093/jbi/wbz062.

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Abstract Objective Breast implant augmentation is the most common cosmetic surgical procedure performed in the United States. The purpose of this study was to determine if patients with breast augmentation surgery are aware of the effect of breast implants on the mammographic detection of cancer. Methods An institutional review board exempt patient awareness survey was distributed at a single breast imaging facility to women undergoing screening mammography. Comparative statistical analyses were performed between patients with and without breast implants. Results The respondents were divided i
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Suh, Lily J., Imran Khan, Christine Kelley-Patteson, Ganesh Mohan, Aladdin H. Hassanein, and Mithun Sinha. "Breast Implant-Associated Immunological Disorders." Journal of Immunology Research 2022 (May 4, 2022): 1–13. http://dx.doi.org/10.1155/2022/8536149.

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Background. Breast implants are commonly placed postbreast cancer reconstruction, cosmetic augmentation, and gender-affirming surgery. Breast implant illness (BII) is a systemic complication associated with breast implants. Patients with BII may experience autoimmune symptoms including fatigue, difficulty concentrating, hair loss, weight change, and depression. BII is poorly understood, and the etiology is unknown. The purpose of this literature review is to characterize BII autoimmune disorders and determine possible causes for its etiology. Methods. The PubMed, Google Scholar, Embase, Web of
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Abdugafforov, Sardor, V. V. Vorotnikov, R. A. Pakhomova, et al. "Abstract P5-10-11: Immediate breast reconstruction using smooth round implants: a retrospective analysis." Clinical Cancer Research 31, no. 12_Supplement (2025): P5–10–11—P5–10–11. https://doi.org/10.1158/1557-3265.sabcs24-p5-10-11.

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Abstract Background: Breast reconstruction with implants is the most common method of immediate reconstruction after mastectomy in patients with breast cancer. Currently, implants with different characteristics are used for this. The choice of implant is most often determined by the thickness of the subcutaneous fat, anatomy, physiology, the patient's wishes and the surgeon's experience with various manufacturers. This directly affects most of the studies conducted, which as a result do not reveal a significant difference between the implants. This study we compare the results of immediate bre
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Webb, Leland H., Victoria L. Aime, Annie Do, Kenneth Mossman, and Raman C. Mahabir. "Textured Breast Implants: A Closer Look at the Surface Debris Under the Microscope." Plastic Surgery 25, no. 3 (2017): 179–83. http://dx.doi.org/10.1177/2292550317716127.

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Background: Texturing of breast implants is done to decrease the risk of associated complications. Each manufacturer utilizes unique and at times proprietary techniques to texture the surface of their implants. Little is known about the integrity of this surface structure texturing or the propensity for the surfaces to shed particulate matter. This study aimed to determine the extent of surface particulate shedding from 3 textured implants approved by the US Food and Drug Administration (FDA), which are manufactured by Allergan, Mentor, and Sientra. Methods: Control images of each of the 3 tex
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Agochukwu-Nwubah, Nneamaka, Ashley Boustany, Margaret Wetzel, Jacob Maus, and Brian Rinker. "Anatomic Implants in Breast Reconstruction: A Comparison of Outcomes and Aesthetic Results Compared to Smooth Round Silicone Implants." Aesthetic Surgery Journal 39, no. 8 (2019): NP322—NP330. http://dx.doi.org/10.1093/asj/sjz074.

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Abstract Background Direct comparison studies of outcomes and aesthetic satisfaction of anatomic implants compared to other implants are scarce in the literature. Objectives The objective of this study was to compare outcomes and aesthetic satisfaction of patients who underwent breast reconstruction with anatomic implants vs other implants (smooth round silicone). Methods A retrospective chart review was performed of patients who underwent implant-based breast reconstruction over 3 years. Outcomes including complications, number of surgeries, need for revisions, and aesthetic satisfaction of p
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Mesa, Felipe, Sebastian Cataño, and Oscar Tuberquia. "Study of Infections in Breast Augmentation Surgery with Implants in 9,691 Patients over 5 Years." Plastic and Reconstructive Surgery - Global Open 9, no. 8 (2021): e3752. http://dx.doi.org/10.1097/gox.0000000000003752.

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Background: This study presents a review of a single retrospective cohort of patients who underwent surgery for breast augmentation with implants, during a period of 5 years, aged 17–60 years (mean 32 years), in a single institution, IQ Interquirofanos, a private clinic in the city of Medellín, Colombia. Method: A single retrospective cohort study was carried out, in which the database of patients who underwent breast augmentation with implants during 5 years was analyzed. Results: In this period of time, 9,691 female patients and a total of 19,382 breast implants implanted by 66 plastic surge
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Jesus, Albertinio Jarquín Delgado, Emir Noguera Echeverría Alexis, Heinar Rodríguez Sosa Sergio, Ignacio Rafael Pérez Carlos, Rodolfo Esquivel Díaz Francisco, and Hugo Solis Reyna Víctor. "Implant-Associated Lymphoma." International Journal Of Medical Science And Clinical Research Studies 03, no. 05 (2023): 887–89. https://doi.org/10.5281/zenodo.7935711.

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Although cases have been reported in women with smooth surface implants as well, textured surface implants have seen the majority of breast implant-associated lymphoma cases. The most typical signs and symptoms are breast lumps, discomfort, and swelling. Clinical, radiographic, and pathological findings are used to make a diagnosis. The basic course of treatment is still removal of the implant and capsule, however in some circumstances stem cell transplantation, chemotherapy, and radiation therapy may be required. Patients with breast implants who exhibit symptoms should be evaluated by doctor
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Pirjavec Mahić, Aleksandra, Damir Grebić, Paola Čargonja, and Domagoj Kustić. "Silicone Gel Breast Implants." Acta medico-historica Adriatica 18, no. 1 (2020): 165–76. http://dx.doi.org/10.31952/amha.18.1.10.

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The authors have provided an in-depth review of the history of saline and silicone gel–filled breast implants. In the history of medicine, no devices have been more scrutinized and thoroughly studied than breast implants. Although we as plastic surgeons recognize and appreciate the benefits that our patients derive from these devices, society as a whole continues to remain skeptical. The reasons for this are complex and multifactorial but appear to be fueled by the media, oppositional organizations, and several trial lawyers. Prior to 1990, when the silicone gel implant controversy began, ther
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Jesus, Albertinio Jarquín Delgado, Emir Noguera Echeverría Alexis, Heinar Rodríguez Sosa Sergio, Ignacio Rafael Pérez Carlos, Rodolfo Esquivel Díaz Francisco, and Hugo Solis Reyna Víctor. "Breast Reconstruction with Implants after Mastectomy." International Journal Of Medical Science And Clinical Research Studies 03, no. 05 (2023): 881–83. https://doi.org/10.5281/zenodo.7935693.

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Breast reconstruction is an important procedure for women who have had a mastectomy due to breast cancer or other diseases. Breast reconstruction can improve self-esteem, body image, and quality of life for women who have experienced breast loss. Breast reconstruction with implants is an effective and popular technique for breast reconstruction after mastectomy. However, it also has its limitations and complications, so it is important for patients and surgeons to work together to select the right technique and minimize the risk of post-operative complications. The choice of implant type, surg
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Myckatyn, Terence M., Jesus M. Duran Ramirez, Jennifer N. Walker, and Blake M. Hanson. "Management of Biofilm with Breast Implant Surgery." Plastic & Reconstructive Surgery 152, no. 5 (2023): 919e—942e. http://dx.doi.org/10.1097/prs.0000000000010791.

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Learning Objectives: After studying this article, the participant should be able to: 1. Understand how bacteria negatively impact aesthetic and reconstructive breast implants. 2. Understand how bacteria infect breast implants. 3. Understand the evidence associated with common implant infection-prevention strategies, and their limitations. 4. Understand why implementation of bacteria-mitigation strategies such as antibiotic administration or “no-touch” techniques may not indefinitely prevent breast implant infection. Summary: Bacterial infection of aesthetic and reconstructive breast implants i
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Oh, Joon Seok, Jae Hoon Jeong, Yujin Myung, et al. "BellaGel breast implant: 6-Year results of a prospective cohort study." Archives of Plastic Surgery 47, no. 3 (2020): 235–41. http://dx.doi.org/10.5999/aps.2019.01858.

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Background This is the first clinical study conducted among Asian women using breast implants manufactured by an Asian company. Four-year data regarding the safety and efficacy of BellaGel breast implants have already been published, and we now report 6-year data.Methods This study was designed to take place over 10 years. It included 103 patients who underwent breast reconstruction or augmentation using BellaGel breast implants. The rates of implant rupture and capsular contracture were measured and analyzed to evaluate the effectiveness of the breast implant.Results At patients’ 6-year posto
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