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1

Kokkonen, Marja, and Lea Pulkkinen. "Examination of the paths between personality, current mood, its evaluation, and emotion regulation." European Journal of Personality 15, no. 2 (2001): 83–104. http://dx.doi.org/10.1002/per.397.

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In an ongoing longitudinal study, a Big Five Personality Inventory was completed by 122 men and 126 women at age 33. At age 36, the Brief Mood Introspection Scale, the Meta‐Evaluation Scale, and the Meta‐Regulation Scale were administered to 140 men and 127 women. The results, based on path analyses, lent support to a hypothesized model, according to which current mood (Negative, Positive, Active, Calm) and mood evaluation (Mood Influence, Typicality and Acceptance, Clarity) mediate the relationship between the Big Five personality traits and emotion regulation strategies (Repair, Dampening, Maintenance). For both sexes, Neuroticism was the most significant trait in terms of emotion regulation. A sex difference emerged: in general, personality traits and mood variables explained emotion regulation more significantly in men. Copyright © 2001 John Wiley & Sons, Ltd.
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2

Bennett, Emelita, Sonja E. Stutzman, Amber D. Hicks, and DaiWai M. Olson. "Exploring Provider Cultural Competence and Patient Mood in an Outpatient Apheresis Unit." Journal of Transcultural Nursing 31, no. 1 (2019): 22–27. http://dx.doi.org/10.1177/1043659619838026.

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Introduction: Health care and culture are important to patient care. Theoretical frameworks, service delivery, and self-awareness are important to the provider/patient. Provider care varies, and studies are needed to understand the current interactions between providers, patients, and culture. Methodology: This was a prospective, descriptive correlational pilot study. Providers and patients completed a baseline assessment of culture, as well as a Brief Mood Introspection Scale at each visit at the patient’s standard of care visit (i.e., visit as part of clinical procedures). Results: The providers and baseline assessment of culture showed higher than average cultural awareness. All four mood subscales show no statistically significant differences in patient or providers’ mood. There were no significant differences in mood when considering differences and similarities between gender, race, and ethnicity. Discussion: There was no difference in patient or provider mood in this study when based on the differences or similarities in gender, race, and ethnicity.
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Jovančević, Ana, Miljan Jović, Nebojša Milićević, Miodrag Milenović, and Miroslav Komlenić. "PROVODLJIVOST KOŽE I PROMENE U IZRAŽENOSTI POZITIVNOG I NEGATIVNOG AFEKTA IZAZVANE GLEDANJEM ISEČKA IZ FILMA U ODNOSU NA OPTIMIZAM I PESIMIZAM." ГОДИШЊАК ЗА ПСИХОЛОГИЈУ 17, no. 1 (2020): 57–70. http://dx.doi.org/10.46630/gpsi.17.2020.04.

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The aim of this paper is to investigate the relation between psychogalvanic reflex and unpleasant affect induced by film, as well as the difference between optimists and pessimists regarding the induction of unpleasant affect. The sample consisted of 42 students from the Faculty of Philosophy in Niš (male, n = 4; female, n =38) aged 18 to 20 (M = 19, SD = 0.54). The following instruments were used: the revised life orientation scale (LOT-R), a brief mood introspection scale (BMIS), and eight-channel polygraph ProComp Infiniti version 4.0. Stimulus was a clip from the film “Sophie’s Choice”. Respondents watched a neutral stimulus before film clip, used as a control measure for recording the basic level of skin conductance of the respondents. The data were analysed by t-test for independent samples (for differences between optimists and pessimists) and t-test for dependent samples (for differences before and after viewing the clip). From the results we can conclude that the mood of optimists, after watching a film clip aimed at induction of unpleasant affect, changes more than the mood of pessimists (p = .000). More precisely, the mood of optimists is more “spoiled” after watching the movie clip, while the mood of pessimists does not change statistically significantly (p = .367). Skin conductance is statistically significant in both optimists (p = .001) and pessimists (p = .005). We can conclude that the induction of affect was different for these two subsamples. In view of this fact, in the subsequent papers researching affect induction, this potentially confunding variable should be taken into account.
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4

Lorish, Christopher D., and Richard Maisiak. "The face scale: A brief, nonverbal method for assessing patient mood." Arthritis & Rheumatism 29, no. 7 (1986): 906–9. http://dx.doi.org/10.1002/art.1780290714.

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5

Saarikallio, Suvi. "Development and Validation of the Brief Music in Mood Regulation Scale (B-MMR)." Music Perception 30, no. 1 (2012): 97–105. http://dx.doi.org/10.1525/mp.2012.30.1.97.

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mood regulation has been shown to be among of the most important reasons for musical engagement, but there has been a lack of a concise measurement instrument for this behavior. The current study focused on developing and testing the Brief Music in Mood Regulation scale (B-MMR), a 21-item self-report instrument for assessing the use of seven different music-related mood-regulation strategies. Two survey studies (N = 1515 and N = 526) were conducted to first develop and then test and validate the instrument. The newly constructed scale showed adequate internal consistency reliabilities and correlated expectedly with measures of general emotion regulation and musical engagement. As a concise and theoretically coherent measure, the B-MMR may prove to be highly applicable for future surveys and comparative studies.
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6

Rodríguez-Testal, Juan Francisco, and María Valdés Díaz. "Brief-Time-Series Analysis of Depressive Symptomatology in Older People." Spanish Journal of Psychology 6, no. 1 (2003): 35–50. http://dx.doi.org/10.1017/s1138741600005199.

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This research shows the utility of systematic data-gathering from older people and of a statistical analysis procedure for interpreting the data. Four cases of institutionalized older people are presented, and their scores of depressive symptomatology over a period of one to two years is analyzed. Time-series analysis showed a significant positive trend of depression symptomatology in two of the cases, perhaps too subtle for detection in routine clinical check-up, but statistically verifiable. In one of these cases, none of the factors of the scale stands out, despite the fact that the general index shows a statistically significant change over the 36 observations made, so that the results obtained are related to the syndrome of depletion or exhaustion. In the second of the cases, we detect a significant change in the depressive mood factor, which may indicate a subclinical depressive form in its initial stages. Continuous registers can reveal valuable information about situations and progress in the evolution of an older person's mood, with regard to natural development, the prelude to a mood disorder, or follow-up in clinical cases.
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7

Martin, Alexandra, Winfried Rief, Antje Klaiberg, and Elmar Braehler. "Validity of the Brief Patient Health Questionnaire Mood Scale (PHQ-9) in the general population." General Hospital Psychiatry 28, no. 1 (2006): 71–77. http://dx.doi.org/10.1016/j.genhosppsych.2005.07.003.

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8

Grodin, Erica N., Spencer Bujarski, Alexandra Venegas, et al. "Reward, Relief and Habit Drinking: Initial Validation of a Brief Assessment Tool." Alcohol and Alcoholism 54, no. 6 (2019): 574–83. http://dx.doi.org/10.1093/alcalc/agz075.

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Abstract Aims Alcohol use disorder is highly heterogeneous. One approach to understanding this heterogeneity is the identification of drinker subtypes. A candidate classification consists of reward and relief subtypes. The current study examines a novel self-report measure of reward, relief, and habit drinking for its clinical correlates and subjective response (SR) to alcohol administration. Methods Non-treatment-seeking heavy drinkers (n = 140) completed the brief reward, relief, habit drinking scale (RRHDS). A subset of this sample (n = 67) completed an intravenous alcohol administration. Individuals were classified into drinker subtypes. A crowdsourced sample of heavy drinkers (n = 187) completed the RRHDS and a validated reward relief drinking scale to compare drinking classification results. Results The majority of the sample was classified as reward drinkers (n = 100), with fewer classified as relief (n = 19) and habit (n = 21) drinkers. Relief and habit drinkers reported greater tonic alcohol craving compared to reward drinkers. Reward drinkers endorsed drinking for enhancement, while relief drinkers endorsed drinking for coping. Regarding the alcohol administration, the groups differed in negative mood, such that relief/habit drinkers reported a decrease in negative mood during alcohol administration, compared to reward drinkers. The follow-up crowdsourcing study found a 62% agreement in reward drinker classification between measures and replicated the tonic craving findings. Conclusions Our findings suggest that reward drinkers are dissociable from relief/habit drinkers using the brief measure. However, relief and habit drinkers were not successfully differentiated, which suggests that these constructs may overlap phenotypically. Notably, measures of dysphoric mood were better at detecting group differences than measures capturing alcohol’s rewarding effects.
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9

Fennell, Melanie J. V., John D. Teasdale, Simon Jones, and Anita Damlé. "Distraction in neurotic and endogenous depression: an investigation of negative thinking in major depressive disorder." Psychological Medicine 17, no. 2 (1987): 441–52. http://dx.doi.org/10.1017/s0033291700025009.

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SynopsisThe effects on depressive thinking and depressed mood of a brief, standardized distraction procedure were examined. In low endogenous patients (scoring 3 or less on the Newcastle Diagnosis Scale (NDS)), distraction significantly reduced the frequency of depressing thoughts. Consistent with Beck's cognitive model of depression, these patients were significantly less depressed after distraction than after a control procedure. In high endogenous patients (scoring 4 or more on the NDS), distraction produced less marked reductions in frequency of depressing thoughts, and no significant change in depressed mood. It is suggested that the relationship between negative thinking and depressed mood differs in the two patient groups.
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10

Koenig, HArold G., Harvey J. Cohen, Dan G. Blazer, Keith G. Meador, and Ron Westlund. "A Brief Depression Scale for Use in the Medically Ill." International Journal of Psychiatry in Medicine 22, no. 2 (1992): 183–95. http://dx.doi.org/10.2190/m1f5-f40p-c4kd-ypa3.

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Objective: Using items from two existing depression scales, we have sought to develop a brief self-rated instrument for detecting major depressive disorder (M.D.D.) in medically ill, hospitalized patients. Method: Forty-two items from the Geriatric Depression Scale (G.D.S.) and Carroll Depression Scale were administered to 559 men under age 40 or over age 70 consecutively admitted to the hospital. Eighty-two M.D.D.'s were diagnosed in this group by structured psychiatric interview. After eliminating 12 items confounded by medical illness, 11 items were selected using regression analysis, correlation with the total score, and factor analysis. The 11-item scale includes an assessment of the five DSM-III-R criteria for M.D.D. which are least confounded by medical illness (mood, suicidal intent, guilt or worthlessness, concentration, and psychomotor agitation). The scale was then tested in 78 medical inpatients who were later assessed for M.D.D. using a structured psychiatric interview. Results: Ten out of twelve M.D.D.'s were identified (83% sensitivity) and depression excluded in 51 of 66 non-depressed subjects (77% specificity) (compared with 82% sensitivity and 76% specificity for the 30-item G.D.S.). Scores on the 11-item scale were also correlated with the G.D.S. (.92), the Zung Depression Scale (.58), and the C.E.S.-D (.67). Conclusion: The 11-item scale is a practical tool for clinicians who screen patients for depression and for investigators who need a brief measure of depression in studies involving medical inpatients.
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11

McIntyre, Roger S., Gary Remington, Christoph U. Correll, et al. "67 Effects of Long-term Valbenazine on Psychiatric Status in Patients with Tardive Dyskinesia and a Primary Mood Disorder." CNS Spectrums 24, no. 1 (2019): 210–11. http://dx.doi.org/10.1017/s109285291900052x.

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AbstractObjectiveValbenazine is approved for tardive dyskinesia (TD) in adults based on clinical trials that included patients with mood disorders (e.g., bipolar disorder, major depressive disorder). In two long-termphase 3 trials, KINECT 3 (NCT02274558) and KINECT 4 (NCT02405091), sustained TD improvements were found in participants who received once-daily treatment with valbenazine (40 or 80mg). Data from these studies were analyzed post hoc to evaluate changes in psychiatric status of patients with a primary mood disorder.MethodsData were pooled from participants with mood disorders in KINECT 3 (6-week double-blind, placebo-controlled period; 42-week double-blind extension period; 4-week drug-free washout) and KINECT 4 (48week open-label treatment; 4-week drug-free washout). At screening, patients must have had a Brief Psychiatric Rating Scale total score <50. Mood changes were evaluated after long-term treatment (Week 48) and washout (Week 52) using the Young Mania Rating Scale (YMRS) and Montgomery-Åsberg Depression Rating Scale (MADRS). For each scale, mean changes from baseline in the total score and individual item scores were analyzed descriptively.ResultsOf the 95 participants with a primary mood disorder (40mg , n=32; 80mg , n=63), 59 (62.1%) were diagnosed with bipolar disorder, 32 (33.7%) with major depressive disorder, and 4 (4.2%) with another mood disorder. A majority of all mood participants received concomitant antidepressants (84.2%) and/or antipsychotics (76.8%) during treatment; other common concomitant medications included antiepileptics (47.4%), anxiolytics (38.9%), and anticholinergics (22.1%). Mean YMRS and MADRS total scores in all mood participants indicated mood symptom stability at baseline (YMRS, 2.7; MADRS, 5.9). This stability was maintained during the studies, as indicated by minimal changes from baseline in mean total scores (YMRS: Week 48, 1.0; Week 52, –1.0; MADRS: Week 48, 0.3; Week52,0.9). Changes in individual items on both scales were also small (<±0.3), indicating no clinically significant changes or worsening in specific mood symptoms or domains.ConclusionsMood symptom stability was maintained in patients with TD and a primary mood disorder who received up to 48 weeks of treatment with once-daily valbenazine in addition to their psychiatric medication(s).Funding Acknowledgements: Neurocrine Biosciences, Inc.
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12

Mansbach, William E., Ryan A. Mace, and Kristen M. Clark. "The Brief Anxiety and Depression Scale (BADS): a new instrument for detecting anxiety and depression in long-term care residents." International Psychogeriatrics 27, no. 4 (2014): 673–81. http://dx.doi.org/10.1017/s1041610214002397.

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ABSTRACTBackground:Depression and anxiety are common among long-term care residents, yet both appear to be under-recognized and under-treated. In our survey of 164 geriatric health care professionals from 34 U.S. states, 96% of respondents reported that a new instrument that rapidly assesses both depression and anxiety is needed. The Brief Anxiety and Depression Scale (BADS) is a new screening tool that can identify possible major depressive episodes (MDE) and generalized anxiety disorders (GAD) in long-term care residents.Methods:The psychometric properties of the BADS were investigated in a sample of 224 U.S. long-term care residents (aged 80.52 ± 9.07). Participants completed a battery of several individually administered mood and cognitive tests, including the BADS. MDE and GAD were diagnosed based on the DSM-IV-TR criteria.Results:Adequate internal consistency and construct validity were found. A principle component analysis (PCA) revealed an Anxiety Factor and a Depression Factor, which explained 50.26% of the total variance. The Anxiety Factor had a sensitivity of 0.73 and specificity of 0.81 for identifying GAD (PPV = 0.69, NPV = 0.84). The Depression Factor had a sensitivity of 0.76 and a specificity of 0.73 for identifying MDE (PPV = 0.77, NPV = 0.72).Conclusions:The BADS appears to be a reliable and valid screening instrument for MDE and GAD in long-term residents. The BADS can be rapidly administered, is sensitive to mood diagnoses in both patients without dementia and with dementia, and produces separate depression and anxiety factor scores that can be used clinically to identify probable mood diagnoses.
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Innes, K. E., T. K. Selfe, C. J. Brown, K. M. Rose, and A. Thompson-Heisterman. "The Effects of Meditation on Perceived Stress and Related Indices of Psychological Status and Sympathetic Activation in Persons with Alzheimer's Disease and Their Caregivers: A Pilot Study." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/927509.

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Objective. To investigate the effects of an 8-week meditation program on perceived stress, sleep, mood, and related outcomes in adults with cognitive impairment and their caregivers.Methods. Community-dwelling adults with a diagnosis of mild cognitive impairment or early-stage Alzheimer’s disease, together with their live-in caregivers, were enrolled in the study. After a brief training, participants were asked to meditate for 11 minutes, twice daily for 8 weeks. Major outcomes included measures of perceived stress (Perceived Stress Scale), sleep (General Sleep Disturbance Scale), mood (Profile of Mood States), memory functioning (Memory Functioning Questionnaire), and blood pressure. Participants were assessed pre- and post-intervention.Results. Ten participants (5 of 6 dyads) completed the study. Treatment effects did not vary by participant status; analyses were thus pooled across participants. Adherence was good (meditation sessions completed/week:X=11.4±1.1). Participants demonstrated improvement in all major outcomes, including perceived stress (P<0.001), mood (overall,P=0.07; depression,P=0.01), sleep (P<0.04), retrospective memory function (P=0.04), and blood pressure (systolic,P=0.004; diastolic,P=0.065).Conclusions. Findings of this exploratory trial suggest that an 8-week meditation program may offer an acceptable and effective intervention for reducing perceived stress and improving certain domains of sleep, mood, and memory in adults with cognitive impairment and their caregivers.
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Pini, Stefano, Valeria de Queiroz, Liliana Dell'Osso, et al. "Cross-sectional similarities and differences between schizophrenia, schizoaffective disorder and mania or mixed mania with mood-incongruent psychotic features." European Psychiatry 19, no. 1 (2004): 8–14. http://dx.doi.org/10.1016/j.eurpsy.2003.07.007.

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AbstractBackground. – The cross-sectional clinical differentiation of schizophrenia or schizoaffective disorder from mood-incongruent psychotic mania or mixed mania is difficult, since pathognomonic symptoms are lacking in these conditions.Aims of the study. – To compare a series of clinical variables related to mood and cognition in patient groups with DSM-III-R diagnosis of schizophrenia, schizoaffective disorder, mood-incongruent psychotic mania and mood-incongruent psychotic mixed mania.Methods. – One hundred and fifty-one consecutive patients were evaluated in the week prior to discharge by using the structured clinical interview for DSM-III-R-patient edition (SCID-P). Severity of psychopathology was assessed by the 18-item version of the brief psychiatric rating scale (BPRS) and negative symptoms by the scale for assessment of negative symptoms (SANS). Level of insight was assessed with the scale to assess unawareness of mental disorders (SUMD).Results. – There were no differences in rates of specific types of delusions and hallucinations between subjects with schizophrenia, schizoaffective disorder, psychotic mania and psychotic mixed mania. SANS factors scores were significantly higher in patients with schizophrenia than in the bipolar groups. Patients with mixed state scored significantly higher on depression and excitement compared to schizophrenia group and, to a lesser extent, to schizoaffective group. Subjects with schizophrenia showed highest scores on the SUMD indicating that they were much more compromised on the insight dimension than subjects with psychotic mania or mixed mania.Conclusion. – Negative rather than affective symptomatology may be a useful construct to differentiate between schizophrenia or schizoaffective disorders from mood-incongruent psychotic mania or mixed mania.
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Kinoshita, Tetsu, Takeshi Tanigawa, Koutatsu Maruyama, and Kanehisa Morimoto. "The effects of bright light treatment via ear canals on quality of sleep and depressive mood among overworked employees: A randomized-controlled clinical trial." Work 67, no. 2 (2020): 323–29. http://dx.doi.org/10.3233/wor-203282.

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BACKGROUND: Many overworked employees need tools to improve their depressive mood or sleep disorder. In Finland, a new device of bright light therapy was developed. OBJECTIVE: Our objective was to evaluate the effect of bright light treatment via ear canals on improving the depressive mood and sleep disorder. METHODS: We conducted a randomized, controlled, crossover designed, open-label trial. We examined 27 participants aged 23–52 years, assigned to either Early treatment or Later treatment groups. The Early treatment group used the device on weekdays for the first 4 weeks, followed by a 4-week observation period. The Later treatment group had an observation period for the first 4 weeks, followed by device treatment for the subsequent 4 weeks. Every Friday, the participants were asked to answer questionnaires: A Self-rating Depression Scale (SDS), an Athens Insomnia Scale (AIS), and a Profile of Mood States (POMS) Brief Form. RESULTS: While no significant effect was found on the SDS following treatment (p = 0.16), the AIS showed a significant improvement (p = 0.004), and the scores for the Depression (D) and Vigor (V) of POMs decreased significantly (p = 0.045, p = 0.006, respectively). CONCLUSIONS: Bright light treatment via ear canals may improve sleep quality and depressive mood.
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Erichsen, Nora-Beata, and Arndt Büssing. "Spiritual Needs of Elderly Living in Residential/Nursing Homes." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/913247.

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While the research on spiritual needs of patients with chronic and life-threatening diseases increases, there is limited knowledge about psychosocial and spiritual needs of elderly living in residential/nursing homes. We were interested in which needs were of relevance at all, and how these needs are related to life satisfaction and mood states. For that purpose we enrolled 100 elderly living in residential/nursing homes (mean age years, 82% women) and provided standardized questionnaires, that is, Spiritual Needs Questionnaire (SpNQ), Brief Multidimensional Life Satisfaction Scale (BMLSS), Quality of Life in Elders with Multimorbidity (FLQM) questionnaire, and a mood states scale (ASTS). Religious needs and Existential needs were of low relevance, while inner peace needs were of some and needs for giving/generativity of highest relevance. Regression analyses revealed that the specific needs were predicted best by religious trust and mood states, particularly tiredness. However, life satisfaction and quality of life were not among the significant predictors. Most had the intention to connect with those who will remember them, although they fear that there is limited interest in their concerns. It remains an open issue how these unmet needs can be adequately supported.
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Signal, T. Leigh, Sarah-Jane Paine, Bronwyn Sweeney, et al. "The prevalence of symptoms of depression and anxiety, and the level of life stress and worry in New Zealand Māori and non-Māori women in late pregnancy." Australian & New Zealand Journal of Psychiatry 51, no. 2 (2016): 168–76. http://dx.doi.org/10.1177/0004867415622406.

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Objective: To describe the prevalence of symptoms of depression and anxiety, and the level of life stress and worry in late pregnancy for Māori and non-Māori women. Methods: In late pregnancy, women completed a questionnaire recording their prior history of mood disorders; self-reported current depressive symptoms (⩾13 on the Edinburgh Postnatal Depression Scale), current anxiety symptoms (⩾6 on the anxiety items from the Edinburgh Postnatal Depression Scale), significant life stress (⩾2 items on life stress scale) and dysfunctional worry (>12 on the Brief Measure of Worry Scale). Results: Data were obtained from 406 Māori women (mean age = 27.6 years, standard deviation=6.3 years) and 738 non-Māori women (mean age = 31.6 years, standard deviation=5.3 years). Depressive symptoms (22% vs 15%), anxiety symptoms (25% vs 20%), significant life stress (55% vs 30%) and a period of poor mood during the current pregnancy (18% vs 14%) were more prevalent for Māori than non-Maori women. Less than 50% of women who had experienced ⩾2 weeks of poor mood during the current pregnancy had sought help. Being young was an independent risk factor for depressive symptoms, significant life stress and dysfunctional worry. A prior history of depression was also consistently associated with a greater risk of negative affect in pregnancy. Conclusion: Antenatal mental health requires at least as much attention and resourcing as mental health in the postpartum period. Services need to specifically target Māori women, young women and women with a prior history of depression.
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McArthur, Alisa D., and Corinne Syrnyk. "On-Campus Animal-Assisted Therapy Events." Society & Animals 26, no. 6 (2018): 616–32. http://dx.doi.org/10.1163/15685306-12341537.

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Abstract Post-secondary students are experiencing more stress than ever before. In an attempt to help alleviate some of this stress, animal-assisted therapy (AAT) events were held on the campus of a small liberal arts institution just prior to final exams in the Fall and Winter terms. All students were invited to mingle with dogs and handlers from a local AAT advocacy group. In Study 1, students were surveyed following the events held in the Fall and Winter and self-reported an improved mood as a result of the events as well as being extremely satisfied with the experience. Similarly, Study 2, held in the subsequent Fall, replicated the findings from Study 1. In addition, the Brief Mood Inspection Scale, administered before and after the event, found students’ mood improved on all three subscales. The implications for future research to fully assess the impact of such events on students are discussed.
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De Souza, Jonas A., Bonnie J. Yap, Fay J. Hlubocky, and Christopher Daugherty. "Relationship between the cancer-specific comprehensive score for financial toxicity (COST), patient-reported outcome, and health-related quality of life (HRQOL) in patients with advanced cancers." Journal of Clinical Oncology 32, no. 31_suppl (2014): 222. http://dx.doi.org/10.1200/jco.2014.32.31_suppl.222.

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222 Background: Financial toxicity is an important Patient Reported Outcome (PRO). Its relationship with HRQOL has not been previously described. Therefore, we report the relationship between financial toxicity and HRQOL in patients with advanced cancers. Methods: HRQOL was measured by the EORTC QLC-C30 global health status and its functional scales. Financial toxicity was assessed by the COST (COmprehensive Score for financial Toxicity), a cancer-specific PRO measure developed in 155 patients with advanced cancers. The Personal Financial Wellness Scale (PFW), a non-cancer specific financial measure, as well as the EORTC perceived financial impact (FI), were used to assess convergent validity. The Marlowe-Crowne Social Desirability Scale and the Brief Profile of Mood States were included to demonstrate divergent validity (i.e., no significant relationship should exist between self-reported financial toxicity and social desirability and total mood disturbance). Spearman’s correlation coefficients were used to assess the strength of relationships. Results: Fifty patients were assessed. All participants were diagnosed with advanced cancers, were receiving treatment at the time of participation, and had received treatment for at least 3 months. A negative correlation existed between the COST and HRQOL as measured by the EORTC (r = -0.32, p < 0.05). The highest correlation was found between COST and the EORTC Emotional Functioning Scale (r = - 0.34, p < 0.05). The COST had high correlations with the PFW scale (r = 0.86, p<0.0001) and FI (r = 0.74, p < 0.0001), indicating convergent validity. The association between financial toxicity and social desirability and mood states were not statistically significant (r = 0.16, p = 0.28 and 0.20, p = 0.15, respectively), indicating divergent validity. Conclusions: Results demonstrate an inverse relationship between patient-reported HRQOL and financial toxicity, suggesting that higher financial toxicity is associated with worse HRQOL in this small sample of patients. There was no correlation between COST and social desirability and mood disturbances, as expected.
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Sutcliffe, Caroline, Lis Cordingley, Alistair Burns, et al. "A New Version of the Geriatric Depression Scale for Nursing and Residential Home Populations: The Geriatric Depression Scale (Residential) (GDS-12R)." International Psychogeriatrics 12, no. 2 (2000): 173–81. http://dx.doi.org/10.1017/s104161020000630x.

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The objective was to develop a new short-form Geriatric Depression Scale (GDS-12R) suitable for older people living in nursing and residential care settings, including those persons with significant cognitive impairment. A total of 308 newly admitted residents of 30 nursing and residential homes in northwest England were interviewed using the Geriatric Depression Scale (GDS-15), the Mini-Mental State Examination, and the Affect Balance Scale (ABS). A 12-item version of the GDS was shown to have greater internal reliability than the 15-item version, because of the context-dependent nature of the deleted items. There was close agreement between the GDS-12R items and another indicator of depressed mood (a single item from the ABS). Furthermore, moderate to high levels of cognitive impairment did not affect the performance of the new version of the scale. The GDS-12R provides researchers and clinicians with a brief, easy-to-administer depression scale that is relevant to residential and nursing home populations.
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Shoda, Haruka, Shoko Yasuda, Jun Nakahara, Ken-ichi Tabei, and Tadao Isaka. "Development of the Japanese version of the Brief Music Mood Regulation Scale and evaluation of its reliability and validity." Japanese journal of psychology 90, no. 4 (2019): 398–407. http://dx.doi.org/10.4992/jjpsy.90.18207.

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22

Shwartz, Susan K., Brad L. Roper, Timothy J. Arentsen, Ellen M. Crouse, and Marcy C. Adler. "The Behavior Rating Inventory of Executive Function®-Adult Version is Related to Emotional Distress, Not Executive Dysfunction, in a Veteran Sample." Archives of Clinical Neuropsychology 35, no. 6 (2020): 701–16. http://dx.doi.org/10.1093/arclin/acaa024.

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Abstract Objective In three studies, we explore the impact of response bias, symptom validity, and psychological factors on the self-report form of the Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A) and the relationship between self-reported executive functioning (EF) and objective performance. Method Each study pulled from a sample of 123 veterans who were administered a BRIEF-A and Minnesota Multiphasic Personality Inventory-2 (MMPI-2) during a neuropsychological evaluation. Participants were primarily middle-aged, and half carried a mood disorder diagnosis. Study 1 examined group differences in BRIEF-A ratings among valid, invalid, and indeterminate MMPI-2 responders. Analyses were conducted to determine the optimal cut-score for the BRIEF-A Negativity Validity scale. In Study 2, relationships were explored among MMPI-2-RF (restructured form) Restructured Clinical (RC) scales, somatic/cognitive scales, and the BRIEF-A Metacognition Index (MI); hierarchical analyses were performed to predict MI using MMPI-2-RF Demoralization (RCd) and specific RC scales. Study 3 correlated BRIEF-A clinical scales and indices with RCd and an EF composite score from neuropsychological testing. Hierarchical analyses were conducted to predict BRIEF-A clinical scales. Results Invalid performance on the MMPI-2 resulted in significantly elevated scores on the BRIEF-A compared to those with valid responding. A more stringent cut-score of ≥4 for the BRIEF-A Negativity scale is more effective at identifying invalid symptom reporting. The BRIEF-A MI is most strongly correlated with demoralization. BRIEF-A indices and scales are largely unrelated to objective EF performance. Conclusions In a veteran sample, responses on the BRIEF-A are most representative of generalized emotional distress and response bias, not actual EF abilities.
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Gómez Sánchez-Lafuente, C., R. Reina Gonzalez, and M. Hernandez Abellán. "Sexual dysfunction and mood stabilizers in bipolar disorder: A review." European Psychiatry 41, S1 (2017): s849. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1682.

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IntroductionMood stabilizers can cause many side effects. Although many of these are well known, like thyroid and renal failure after taking lithium, sexual dysfunction side effects remains unclear.MethodsWe made a systematic computerized literature search of clinical studies using MEDLINE, The Cochrane Library and Trip for clinical studies of sexual dysfunction published up to December 2015.ResultsOnly eight relevant papers were identified. All of them studied lithium sexual dysfunction in bipolar disorder patients. Valproic acid, carbamazepine and lamotrigine were not studied in patients with bipolar disorder. Nevertheless, the three were studied in epilepsy. Clinical reports usually used Arizona Sexual Experience Scale or Psychotropic Related Sexual Dysfunction Questionnaire to measure sexual dysfunction and Brief Adherence Rating Scale to measure medication adherence. They suggest lithium could decrease desire and sexual thoughts, worse arousal and cause orgasm dysfunction. In overall, those patients with sexual dysfunction had lower level of functioning and poor compliance. Taking benzodiazepines during lithium treatment may increase the risk of sexual dysfunction even more.ConclusionThere are few studies that focus on mood stabilizers sexual dysfunction. This inevitably entails a number of limitations. First, the small sample size and, in some studies, the relative short period of follow-up may underestimate the results. Besides, practical management was not treated in any study. Actually, handling this side effect have not been well established.To conclude, this revision suggest that approximately 30% patients receiving lithium experience this side effect, and it is associated with poor medication adherence.Disclosure of interestThe authors have not supplied their declaration of competing interest.
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Feggi, A., C. Gramaglia, C. Guerriero, F. Bert, R. Siliquini, and P. Zeppegno. "Resilience, Coping, Personality Traits, Self-Esteem and Quality of Life in Mood Disorders." European Psychiatry 33, S1 (2016): S518. http://dx.doi.org/10.1016/j.eurpsy.2016.01.1915.

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IntroductionResilience is a dynamic, context- and time-specific process that refers to positive adaptation or ability to maintain or regain mental health despite experiencing adversity. Pathways to resilience include biological, psychological, social and dispositional attributes. In mood disorders, resilience may influence frequency of relapse, severity of episodes and response to treatment.AimsTo evaluate resilience as well as personality features, coping abilities, self-esteem and quality of life in a sample of mood disorder patients.MethodsWe recruited mood disorder patients at the Psychiatry institute AOU Maggiore della Carità, Novara. Socio-demographic data were gathered and patients filled in the following self-administered scales: Resilience Scale for Adult (RSA), Brief Cope, Rosenberg Self-Esteem Scale (RSES), Paykel list of stressful events, Temperamental and Character Inventory (TCI), Quality of life (SF-36).ResultsWe collected data from 61 patients. Statistical analysis was performed by calculating the Pearson Correlation Coefficient between the RSA and the other tests. We observed a positive correlation between RSA and coping “Emotion” and coping “Problem”. A negative correlation was found between RSA and coping “Avoidance”. Resilience was also positively related to self-esteem and physical, mental and general health. As far as personality traits are concerned, resilience was positively correlated with Reward dependence, persistence, self transcendence, self directedness and cooperativeness.ConclusionsSince higher resilience levels are related with better physical and mental health, constructive coping and self-esteem, strategies aimed at enhancing resilience could improve treatment and quality of life in patients with mood disorders.Disclosure of interestThe authors have not supplied their declaration of competing interest.
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Fernández-Martínez, Elena, Ana I. López-Alonso, Pilar Marqués-Sánchez, María Cristina Martínez-Fernández, Leticia Sánchez-Valdeón, and Cristina Liébana-Presa. "Emotional Intelligence, Sense of Coherence, Engagement and Coping: A Cross-Sectional Study of University Students’ Health." Sustainability 11, no. 24 (2019): 6953. http://dx.doi.org/10.3390/su11246953.

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It is important to consider university settings as sustainable environments that promote student well-being. Our aim in this study was to determine how the variables of engagement, emotional intelligence, sense of coherence, and coping influence the health of students at a Spanish university. This was a descriptive, cross-sectional study. The instruments of measures administered were: The General Health Questionnaire, Trait Meta-Mood Scale, Uterch Work Engagement Scale, sense of coherence and brief coping scale to 463 students. The results showed that better-perceived health was associated with higher scores for dedication, vigor, clarity, repair, sense of coherence, active coping, positive reframing, and humor. Conversely, poorer perceived health was associated with higher scores for attention, instrumental support, self-distraction, venting, religion, denial, self-blaming, emotional support, and behavioral disengagement. In addition, the variables analyzed presented differences by sex. Our proposed predictive model of health and the associations between variables indicate the need to cultivate emotional skills, such as mood repair, a sense of coherence, and coping strategies, in order to promote student health. Facilitating students’ acquisition of knowledge and resources by analyzing these and other variables can contribute to individual well-being and help university students to cope with present and future academic challenges.
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Nipp, Ryan David, Areej El-Jawahri, William F. Pirl, et al. "Quality of life and mood in patients with advanced cancer: Associations with prognostic understanding and coping style." Journal of Clinical Oncology 33, no. 29_suppl (2015): 76. http://dx.doi.org/10.1200/jco.2015.33.29_suppl.76.

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76 Background: Patients’ prognostic understanding and coping styles influence their treatment decisions, but how these factors relate to their quality of life (QOL) and mood has not been well described. We sought to examine the associations of patients’ prognostic understanding and coping style with their QOL and mood. Methods: As part of an ongoing trial of early palliative care, we are assessing baseline QOL (Functional Assessment of Cancer Therapy-General), mood (Hospital Anxiety and Depression Scale), coping (Brief Cope) and prognostic understanding in patients within 8 weeks of diagnosis of advanced lung or gastrointestinal (GI) cancer. To determine associations, we used linear and logistic regression, controlling for patients’ age, sex, cancer type and marital status. Results: Of 300 participants (mean age = 64.7 years; 138 (46%) female), 132 (44%) had GI cancer and 168 (56%) had lung cancer. Using cutoff score > 7 for the HADS, 61 (20%) and 85 (28%) reported depression and anxiety. 138 (49%) reported their prognosis as terminal. A terminal perception of prognosis was associated with lower QOL and higher rates of anxiety. Emotional support, acceptance, and active coping styles were associated with better QOL and mood. Denial and self blame were associated with worse QOL and mood. Conclusions: These data demonstrate that acknowledging a terminal prognosis may be associated with greater physical and psychological distress, or conversely, patients with worse QOL and mood may better appreciate the gravity of their illness. Certain coping styles (self blame and denial) are associated with lower QOL and higher distress. Understanding the relationships among patients’ prognostic awareness, coping styles, QOL and mood will allow us to develop more effective supportive care interventions. Clinical trial information: NCT01401907. [Table: see text]
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Carleton, R. Nicholas, Kelsey C. Collimore, Randi E. McCabe, and Martin M. Antony. "Addressing revisions to the Brief Fear of Negative Evaluation scale: Measuring fear of negative evaluation across anxiety and mood disorders." Journal of Anxiety Disorders 25, no. 6 (2011): 822–28. http://dx.doi.org/10.1016/j.janxdis.2011.04.002.

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Elyze, Madeleine, Jamie M. Jacobs, Ashley Nelson, et al. "Enhanced coping and self-efficacy in caregivers of hematopoietic stem cell transplant (HCT) recipients: Identifying mechanisms of a multimodal psychosocial intervention." Journal of Clinical Oncology 38, no. 15_suppl (2020): 12122. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.12122.

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12122 Background: A brief multimodal psychosocial intervention (BMT-CARE) for caregivers of HCT recipients demonstrated promising efficacy for improving caregiver quality of life (QOL), mood, coping skills, and self-efficacy. We examined whether improvements in coping and self-efficacy mediated the intervention effects on QOL and mood. Methods: We conducted a randomized clinical trial of BMT-CARE for caregivers of patients undergoing autologous or allogeneic HCT at a single institution. Caregivers were randomly assigned to BMT-CARE or usual care. BMT-CARE was tailored to the HCT trajectory and integrated treatment-related education and self-care with cognitive-behavioral skills and caregiving-specific strategies to promote coping. Caregivers completed self-report measures of QOL (CareGiver Oncology QOL), depression and anxiety symptoms (Hospital Anxiety and Depression Scale), coping skills (Measure of Current Status), and self-efficacy (Cancer Self-Efficacy Scale-Transplant) at enrollment and 60 days post-HCT. We used causal mediation regression models to examine whether changes in coping and self-efficacy mediated intervention effects on QOL, depression and anxiety symptoms. Results: Caregivers randomized to BMT-CARE reported improved self-efficacy (adjusted means: 156.20 vs. 147.06, P=0.023) and coping skills (adjusted means: 36.54 vs. 25.41, P<0.001). Improved coping and self-efficacy partially mediated the intervention effects on 60-day QOL (indirect effect=6.93, SE=1.85, 95% CI [3.71, 11.05]). Similarly, improved coping and self-efficacy partially mediated reductions in 60-day depression and anxiety symptoms (indirect effect depression=-1.19, SE=0.42, 95% CI [-2.23, -0.53]; indirect effect anxiety=-1.46, SE=0.55, 95% CI [-2.52, -0.43]). Combined improvements in coping and self-efficacy accounted for 67%, 80%, and 39% of the total intervention effect on QOL and depression and anxiety symptoms, respectively. Conclusions: A brief multimodal intervention for caregivers of HCT recipients may improve QOL and mood by enhancing coping skills and self-efficacy. These findings offer important insights into the mechanisms by which caregiver-directed interventions may enhance caregiver QOL and reduce their psychological distress.
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Kovach, Christine. "DO WARMED BLANKETS CHANGE PAIN, AGITATION, MOOD, OR ANALGESIC USE AMONG NURSING HOME RESIDENTS?" Innovation in Aging 3, Supplement_1 (2019): S623. http://dx.doi.org/10.1093/geroni/igz038.2320.

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Abstract Warmed blankets have not been empirically tested for use in long-term care. The purpose of this study was to describe the use of warmed blankets in a nursing home setting and to determine if use was associated with changes in pain, agitation, mood, or analgesic use. Short-term measures were compared from baseline to post warmed blanket use and longer term differences were compared between those receiving warmed blankets and a randomly selected comparison group. Excluded from eligibility were those using a transdermal drug, with an acute injury, acute inflammatory process, multiple sclerosis, open skin wound, or other condition that could be worsened by superficial heat. Measures included the Revised Faces Pain Scale, PAIN-AD scale, the Brief Agitation Rating Scale, and from the electronic medical record one month measures pain complaints, pain severity, and analgesic use. Long-term measures were taken from the electronic medical record. Of the 141 eligible residents, 24.1% (n = 34) received a warmed blanket over the one month study period. There were statistically significant decreases in both pain level and agitation between baseline, 20 minutes after application, and the subsequent shift assessments (p < .001). There were also long-term changes in the number of pain complaints (p = .040), severity of pain complaints (p = .009), and prn analgesic use (p = .011). There were no statistically significant differences between the treated group and comparison group on any long-term measures. Warmed blankets are a low-cost intervention with a high potential for bringing comfort to nursing home residents.
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Shoemark, Helen, Marie Dahlstrøm, Oscar Bedford, and Lauren Stewart. "The Effect of a Voice-Centered Psycho-Educational Program on Maternal Self-Efficacy: A Feasibility Study." International Journal of Environmental Research and Public Health 18, no. 5 (2021): 2537. http://dx.doi.org/10.3390/ijerph18052537.

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This study examined the effect of a brief psycho-educational program, Time Together, on maternal self-efficacy, mother-infant bonding, and mood/anxiety for community-based mothers. This program centered on maternal voice, timing of interplay, and recognition of infant cues. A convergent parallel mixed-methods design included quantitative measures: the Karitane Parenting Confidence Scale, the Mother-Infant Bonding Scale, Edinburgh Postnatal Depression Scale and State & Trait Anxiety Inventory, and a sequential qualitative analysis to elaborate on the quantitative findings. Significant changes on the Karitane Parenting Confidence Scale were found. Qualitative analysis of the participant interviews and reflective diaries from the two weeks following the psycho-educational program confirmed that participation enhanced mothers’ ability to understand their infant, to soothe their infant when distressed, to play and to establish an effective bedtime routine. This feasibility study indicated that this is a promising approach to improve early mother-infant interaction and maternal self-efficacy.
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Baryshnikov, I., K. Aaltonen, M. Koivisto, et al. "Self-reported psychosis-like experiences in patients with mood disorders." European Psychiatry 51 (June 2018): 90–97. http://dx.doi.org/10.1016/j.eurpsy.2016.07.005.

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AbstractBackground:Self-reported psychosis-like experiences (PEs) may be common in patients with mood disorders, but their clinical correlates are not well known. We investigated their prevalence and relationships with self-reported symptoms of depression, mania, anxiety, borderline (BPD) and schizotypal (SPD) personality disorders among psychiatric patients with mood disorders.Methods:The Community Assessment of Psychic Experiences (CAPE-42), Mood Disorder Questionnaire (MDQ), McLean Screening Instrument (MSI), The Beck Depressive Inventory (BDI), Overall Anxiety Severity and Impairment Scale (OASIS) and Schizotypal Personality Questionnaire-Brief form (SPQ-B) were filled in by patients with mood disorders (n=282) from specialized care. Correlation coefficients between total scores and individual items of CAPE-42 and BDI, SPQ-B, MSI and MDQ were estimated. Hierarchical multivariate regression analysis was conducted to examine factors influencing the frequency of self-reported PE.Results:PEs are common in patients with mood disorders. The “frequency of positive symptoms” score of CAPE-42 correlated strongly with total score of SPQ-B (rho=0.63; P<0.001) and moderately with total scores of BDI, MDQ, OASIS and MSI (rho varied from 0.37 to 0.56; P<0.001). Individual items of CAPE-42 correlated moderately with specific items of BDI, MDQ, SPQ-B and MSI (rφ varied from 0.2 to 0.5; P<0.001). Symptoms of anxiety, mania or hypomania and BPD were significant predictors of the “frequency of positive symptoms” score of CAPE-42.Conclusions:Several, state- and trait-related factors may underlie self-reported PEs among mood disorder patients. These include cognitive-perceptual distortions of SPD; distrustfulness, identity disturbance, dissociative and affective symptoms of BPD; and cognitive biases related to depressive or manic symptoms.
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Perkins-Porras, Linda, Muhammad Riaz, Adeoba Okekunle, Svitlana Zhelezna, Indranil Chakravorty, and Michael Ussher. "Feasibility study to assess the effect of a brief mindfulness intervention for patients with chronic obstructive pulmonary disease: A randomized controlled trial." Chronic Respiratory Disease 15, no. 4 (2018): 400–410. http://dx.doi.org/10.1177/1479972318766140.

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Psychological distress is common among patients with chronic obstructive pulmonary disease (COPD). This study aimed to assess whether a 10-minute mindfulness intervention reduces distress and breathlessness, improves mood and increases mindfulness among hospital inpatients following acute exacerbation of COPD.Fifty patients were recruited following an acute admission. The immediate effects of a 10-minute mindfulness-based body scan were compared with a control intervention. Participants were randomized to receive either a mindfulness-based body scan ( n = 24) or a control condition ( n = 26) via a 10-minute audio recording. Participants completed a self-assessment survey, including the Borg scale for breathlessness, Philadelphia Mindfulness Scale and Hospital Anxiety and Depression Scale. They then completed six brief single item measures of dyspnoea, anxiety, depression, happiness, stress and mindfulness before and after the intervention daily for three consecutive days. Acceptability was rated according to ‘usefulness’ and whether they would recommend the intervention to other patients. Results showed that there was a tendency for change in most outcomes, but no significant differences between the groups. Most participants rated the intervention as useful and would recommend it. Existing knowledge of mindfulness interventions among these patients is very limited and this study may be helpful in the development of other brief interventions.
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Niccols, Alison, Charles Cunningham, Peter Pettingill, Donna Bohaychuk, and Eric Duku. "Infant mental health: The Brief Child and Family Intake and Outcomes System." International Journal of Behavioral Development 42, no. 6 (2018): 588–96. http://dx.doi.org/10.1177/0165025417752497.

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There is a need to identify children with potential mental health issues early in order to provide “an ounce of prevention.” Unfortunately, there are few instruments available to identify emotional and behavioral issues in infants and many never receive intervention. We developed the Brief Child and Family Intake and Outcomes System for Infants, which is a standardized online parent questionnaire including one externalizing scale (Cooperating), two internalizing scales (Expressing Emotion; Responding to Change), and two regulatory scales (Eating; Sleeping). We conducted a normative study of 542 Canadian children aged 8–17 months, stratified by sex, age, geographic region, and parents’ marital status, income, and education. Results of confirmatory factor analyses demonstrated good model fit and the relationship between items and subscales did not vary significantly between boys and girls or between younger and older infants. Reliability estimates indicated high internal consistency and adequate to high test-retest reliability. Providing preliminary evidence of validity, scale scores had moderate to strong positive relations with measures of family distress, caregiver mood, and demographic variables. Analyses of latent variables revealed good evidence of discriminant validity of the scales. We extend earlier work by addressing a very young age range, including subscales particularly relevant to infant emotional and behavioral regulation while at the same time minimizing respondent burden, and providing norms for Canadian infants. The questionnaire could be used in children’s mental health settings, primary care, child welfare, and daycare facilities, for intake, triage, and describing infants.
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Allely, Clare S. "Fire-setting and psychopathology: a brief overview of prevalence, pathways and assessment." Journal of Criminal Psychology 9, no. 4 (2019): 149–54. http://dx.doi.org/10.1108/jcp-06-2019-0022.

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Purpose There is increasing attention on investigating the association between fire-setting and psychopathology and also the degree to which fire-setting is a manifestation of mental disorder. Despite the actual prevalence of pyromania remaining elusive, there is growing evidence in the literature highlighting the higher rates of psychiatric mental health disorders in fire-setters, the most common being: schizophrenia, mood disorders (such as anxiety and depression), personality disorders, alcohol abuse and intellectual disability. The purpose of this paper is to highlight more recent work on prevalence, pathways and assessment in offenders who have engaged in fire-setting. Design/methodology/approach This paper provides an overview of the literature on fire-setting and psychopathology with a focus on prevalence, pathways and assessment. Findings This review identified key literature which has identified a variety of distinct pathways to fire-setting and also highlights two assessments/measures for fire-setters. Such information is useful for clinicians when they encounter this group of offenders. Practical implications This paper has identified in the literature and recommends the use of the “Fire Setting Scale” and the “Fire Proclivity Scale” in clinical and/or forensic practice. Originality/value There is a very real need for additional empirical research in this area. There is also a need for an increased awareness and understanding of how various types of psychopathy can contribute to fire-setting in both a legal and clinical context.
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Drummond, Avril, Louise Hawkins, Nikola Sprigg, et al. "The Nottingham Fatigue after Stroke (NotFAST) study: factors associated with severity of fatigue in stroke patients without depression." Clinical Rehabilitation 31, no. 10 (2017): 1406–15. http://dx.doi.org/10.1177/0269215517695857.

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Objective: To identify factors associated with post-stroke fatigue in a sample of stroke survivors without depression. Design: Cross-sectional cohort study. Setting: Recruitment was from four stroke units in the UK. Subjects: Participants were assessed within four to six weeks of first stroke; those with high levels of depressive symptoms (score ⩾7 Brief Assessment Schedule Depression Cards) were excluded. Main measures: Participants were assessed after stroke on the Fatigue Severity Scale of the Fatigue Assessment Inventory, the Rivermead Mobility Index, Nottingham Extended Activities of Daily Living scale, Beck Anxiety Index, Sleep Hygiene Index, 6m walk test, and measures of cognitive ability. Results: Of the 371 participants recruited, 103 were excluded and 268 were assessed. Of the latter, the mean age was 67.7 years (SD 13.5) and 168 (63%) were men. The National Institutes of Health Stroke Scale mean score was 4.96 (SD 4.12). Post-stroke fatigue was reported by 115 (43%) of participants, with 71 (62%) reporting this to be a new symptom since their stroke. Multivariate analysis using the Fatigue Severity Scale as the outcome variable found pre-stroke fatigue, having a spouse/partner, lower Rivermead Mobility Index score, and higher scores on both the Brief Assessment Schedule Depression Cards and Beck Anxiety Index were independently associated with post-stroke fatigue, accounting for approximately 47% of the variance in Fatigue Severity Scale scores. Conclusions: Pre-stroke fatigue, lower mood, and poorer mobility were associated with post-stroke fatigue.
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Anie, Kofi A., John Green, Philip Tata, Christina E. Fotopoulos, Lola Oni, and Sally C. Davies. "SELF-HELP MANUAL-ASSISTED COGNITIVE BEHAVIOURAL THERAPY FOR SICKLE CELL DISEASE." Behavioural and Cognitive Psychotherapy 30, no. 4 (2002): 451–58. http://dx.doi.org/10.1017/s135246580200406x.

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The feasibility of using a self-help treatment manual to assist a cognitive behavioural therapy programme developed with the aim of improving pain coping ability and quality of life, and reducing psychological distress in sickle cell patients was evaluated. Adult patients attending a London hospital outpatient sickle cell clinic were invited to 12-week cognitive behavioural therapy. Outcome was assessed with measures of pain status, health service utilization, psychological coping (Coping Strategies Questionnaire-revised for Sickle Cell Disease), quality of life (Medical Outcomes Survey Short Form 36), and mood (Hospital Anxiety and Depression Scale). Baseline disease severity data were also collected. No significant differences in baseline data were observed between patients who completed cognitive behavioural therapy and “dropouts”. Improvements over baseline at 12 weeks in patients who completed cognitive behavioural therapy were significant. Active coping and use of physician advised methods for pain increased. Emotional responses decreased, general health and vitality improved, while anxiety reduced. This demonstrates that a brief manual-assisted cognitive behavioural therapy programme is feasible in sickle cell disease, and may help to improve coping, quality of life and mood.
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Scott, Jan, Elizabeth M. Scott, Daniel F. Hermens, et al. "Functional impairment in adolescents and young adults with emerging mood disorders." British Journal of Psychiatry 205, no. 5 (2014): 362–68. http://dx.doi.org/10.1192/bjp.bp.113.134262.

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BackgroundBetween 30 and 60% of adults with unipolar or bipolar disorders exhibit impairments across multiple domains. However, little is known about impaired functioning in youth with mood disorders.AimsTo examine the prevalence of objective, subjective and observer-rated disability in a large, representative sample of young people with a primary mood disorder.MethodIndividuals aged 16–25 years presenting to youth mental health services for the first time with a primary mood disorder participated in a systematic diagnostic and clinical assessment. Impairment was assessed using objective (unemployment or disability payments), observer- (Social and Occupational Functioning Assessment Scale; SOFAS) and self-rated measures (role functioning according to the Brief Disability Questionnaire).ResultsOf 1241 participants (83% unipolar; 56% female), at least 30% were functionally impaired on the objective, self-rated and/or observer-rated measures, with 16% impaired according to all three criteria. Even when current distress levels were taken into account, daily use of cannabis and/or nicotine were significantly associated with impairment, with odds ratios (OR) ranging from about 1.5 to 3.0. Comorbid anxiety disorders were related to lower SOFAS scores (OR = 2–5).ConclusionsLevels of disability were significant, even in those presenting for mental healthcare for the first time. Functional impairment did not differ between unipolar and bipolar cases, but some evidence suggested that females with bipolar disorder were particularly disabled. The prevalence of comorbid disorders (50%) and polysubstance use (28%) and their association with disability indicate that more meaningful indicators of mood episode outcomes should focus on functional rather than symptom-specific measures. The association between functioning and nicotine use requires further exploration.
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Garcia-Alvarez, Alicia, Corbin A. Cunningham, Byron Mui, et al. "A randomized, placebo-controlled crossover trial of a decaffeinated energy drink shows no significant acute effect on mental energy." American Journal of Clinical Nutrition 111, no. 3 (2020): 719–27. http://dx.doi.org/10.1093/ajcn/nqz343.

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ABSTRACT Background “Energy drinks” are heavily marketed to the general public, across the age spectrum. The efficacy of decaffeinated energy drinks in enhancing subjective feelings of energy (s-energy) is controversial. Objective The authors sought to test the efficacy of the caffeine-free version of a popular energy drink compared with a placebo drink. Methods This study was a randomized, double-blind, placebo-controlled, crossover trial in 223 healthy men and women aged 18–70 y with intention-to-treat and completers analysis. Participants were randomly assigned to consumption of either the decaffeinated energy drink or a placebo drink on testing day 1, and the other drink a week later. A battery of computer-based mood and cognitive tests to assess s-energy was conducted at baseline and at 0.5, 2.5, and 5 h post-ingestion. The main outcome measures were 1) mood, which was assessed by using a General Status Check Scale and the Profile of Mood States 2nd edition brief form, and 2) cognitive measures, including the N-back task (reaction time and accuracy), Reaction Time test, Flanker task (distraction avoidance), and Rapid Visual Information Processing test. Results No statistically significant or meaningful benefits were observed for any outcome measure, including mood and cognitive measures. Analyses of mean differences, slopes, and median differences were consistent. Conclusions No differences were detected across a range of mood/cognitive/behavioral/s-energy–level tests after consumption of the energy drink compared with a placebo drink in this diverse sample of adults. Thus, we found strong evidence that the energy drink is not efficacious in enhancing s-energy levels, nor any related cognitive or behavioral variables measured. In light of federal regulations, these findings suggest that labeling and marketing of some products which claim to provide these benefits may be unsubstantiated. This trial was registered at www.clinicaltrials.gov as NCT02727920.
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Sarna, Linda, Mary E. Cooley, Jean K. Brown, Cynthia Chernecky, David Elashoff, and Jenny Kotlerman. "Symptom Severity 1 to 4 Months After Thoracotomy for Lung Cancer." American Journal of Critical Care 17, no. 5 (2008): 455–67. http://dx.doi.org/10.4037/ajcc2008.17.5.455.

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Background Information about the severity of symptoms during recovery from surgery for lung cancer can be useful in planning and anticipating needs for recovery. Objectives To describe symptom severity during the first 4 months after thoracotomy for non–small cell lung cancer and factors associated with overall symptom severity at 1 and 4 months. Methods Ninety-four patients were assessed at 1, 2, and 4 months after thoracotomy by using the Lung Cancer Symptom Scale, Brief Pain Inventory, Schwartz Fatigue Scale, Dyspnea Index, and Center for Epidemiology Studies–Depression Scale (CES-D). Clinically meaningful changes, decrease in the proportion of patients with severe symptoms, and relationships among symptoms were determined. Mixed effects models for repeated measures were used to evaluate changes in severity. Multiple regression models were used to examine correlates of overall symptoms. Results Mean symptom severity significantly decreased over time for most symptoms. Only disrupted appetite, pain, and dyspnea had clinically meaningful improvement at 4 months. Severe symptoms included fatigue (57%), dyspnea (49%), cough (29%), and pain (20%). Prevalence of depressed mood decreased at 4 months. Most patients (77%) had comorbid conditions. Number of comorbid conditions and CES-D explained 54% of the variance in symptom severity at 1 month; comorbid conditions, male sex, neoadjuvant treatment, and CES-D score explained 50% of the variance at 4 months. Conclusions Severe symptoms continued 4 months after surgery for some patients, indicating the need for support during recovery, especially for patients with multiple comorbid conditions and depressed mood.
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Wilson, Julianne, Amanda R. Rabinowitz, and Tessa Hart. "A-111 Ecological Momentary Assessment of Mood after Moderate to Severe Traumatic Brain Injury." Archives of Clinical Neuropsychology 36, no. 6 (2021): 1160. http://dx.doi.org/10.1093/arclin/acab062.129.

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Abstract Objective In persons with moderate–severe traumatic brain injury (msTBI), we compared traditional measures of mood with dynamic measures of affect derived from ecological momentary assessment (EMA), for the purpose of validating the EMA indices and exploring their unique contributions to emotional assessment. Method 23 community-dwelling participants with chronic msTBI were enrolled in a treatment trial for anxiety and/ or depression. At baseline, participants completed the Brief Symptom Inventory-18 Depression and Anxiety subscales (BSI-D, BSI-A) and the Environmental Reward Observation Scale (EROS), a measure of everyday pleasure and reward. EMA data, including the Positive and Negative Affect Scale (PANAS), were collected via smartphone 5 times daily for 7–14 days prior to treatment (M = 8.65; SD = 1.87). Spearman correlations tested associations between baseline BSI-D, BSI-A, and EROS scores with both overall means and temporal variability measures for positive and negative affect (PA, NA). Results Mean PA was significantly correlated with BSI-D (rho −0.60, p < 0.05) and EROS (rho 0.72, p < 0.01). Mean NA and affect variability measures were uncorrelated with baseline scores. NA mean and variability were intercorrelated (rho 0.87, p < 0.001), but this was not the case for PA. Conclusion EMA measures of averaged positive affect showed robust relationships with retrospective measures of depression and environmental reward, providing support for the validity of EMA measures of PA, and for use of the EROS in msTBI. While negative findings must be interpreted with caution, the lack of association of affective variability with retrospective measures suggest a unique role for EMA in examining temporal dynamics of affect.
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Nipp, Ryan D., Joseph A. Greer, Areej El-Jawahri, et al. "Coping and Prognostic Awareness in Patients With Advanced Cancer." Journal of Clinical Oncology 35, no. 22 (2017): 2551–57. http://dx.doi.org/10.1200/jco.2016.71.3404.

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Purpose Patients’ understanding of their illness is key for making informed treatment decisions, yet studies suggest an association between prognostic awareness and worse quality of life (QOL) and mood among patients with advanced cancer. We sought to explore the relationships among prognostic awareness, coping, QOL, and mood in patients with newly diagnosed, incurable cancer. Methods We assessed patients’ self-reported health status and treatment goal (Prognosis and Treatment Perceptions Questionnaire), coping (Brief COPE), QOL (Functional Assessment of Cancer Therapy-General), and mood (Hospital Anxiety and Depression Scale) within 8 weeks of incurable lung or GI cancer diagnosis. We used linear regression to examine associations and interaction effects among patients’ health status and treatment goal, coping strategies, QOL, and mood. Results Patients who reported a terminally ill health status had worse QOL (unstandardized coefficient [B] = −6.88; P < .001), depression (B = 1.60; P < .001), and anxiety (B = 1.17; P = .007). Patients who reported their oncologist’s treatment goal was “to cure my cancer” had better QOL (B = 4.33; P = .03) and less anxiety (B = −1.39; P = .007). We observed interaction effects between self-reported health status and treatment goal and certain coping strategies. Specifically, subgroup analyses showed that greater use of positive reframing was related to better QOL (B = 2.61; P < .001) and less depression (B = −0.78; P < .001) among patients who reported a terminally ill health status. Active coping was associated with better QOL (B = 3.50; P < .001) and less depression (B = −1.01; P < .001) among patients who acknowledged their oncologist’s treatment goal was not “to cure my cancer.” Conclusion Prognostic awareness is related to worse QOL and mood in patients with newly diagnosed, incurable cancer; however, the use of certain coping strategies may buffer these relationships. Interventions to improve patients’ prognostic awareness should seek to cultivate more adaptive coping strategies in order to enhance QOL and mood.
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Soares, Marcia Britto de Macedo, Ricardo Alberto Moreno, and Doris Hupfeld Moreno. "Electroconvulsive therapy in treatment-resistant mania: case reports." Revista do Hospital das Clínicas 57, no. 1 (2002): 31–38. http://dx.doi.org/10.1590/s0041-87812002000100006.

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Electroconvulsive therapy is known to be effective in the treatment of mood disorders, more specifically for depression and mania. Although a large body of evidence confirms the efficacy of electroconvulsive therapy in the treatment of mania, few prospective studies have been done to assess its effectiveness in treatment-resistant manic episodes. These case reports describe the initial results of a study that is being conducted to evaluate the efficacy of Electroconvulsive therapy among treatment-resistant bipolar patients. METHODS: Three manic patients (according to DSM-IV criteria) who were considered treatment-resistant underwent a series of 12 bilateral Electroconvulsive therapy sessions. Before the treatment and then weekly, they were evaluated with the following rating scales: Young Mania Rating Scale, Hamilton Rating Scale for Depression, Brief Psychiatric Rating Scale, and Clinical Global Impressions-Bipolar Version. RESULTS: The 3 patients showed a satisfactory response to Electroconvulsive therapy, although some differences in the course of response were observed. CONCLUSION: These case reports suggest that Electroconvulsive therapy needs further evaluation for the treatment of resistant bipolar patients.
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van Beek, J., P. J. Vuijk, J. M. Harte, and E. J. A. Scherder. "Symptom Profile of Psychiatric Patients With Psychosis or Psychotic Mood Disorder in Prison." International Journal of Offender Therapy and Comparative Criminology 62, no. 13 (2018): 4158–73. http://dx.doi.org/10.1177/0306624x18757116.

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There is evidence that psychiatric patients with psychotic or manic disorders who are incarcerated suffer from the same symptoms as psychiatric patients who are treated in the community. There are also indications that their symptoms might be more severe. The aim of this study was to examine the severity of psychotic and manic symptoms, as well as to collect information about the emotional functioning of patients admitted to a prison psychiatric ward. Incarcerated patients with a diagnosis of psychotic or a manic disorder were examined with the Brief Psychiatric Rating Scale–Expanded (BPRS-E). With the scores of 140 assessments, a symptom profile was created using the domains of the BPRS-E. This profile was compared with the clinical profile of three nonincarcerated patient groups described in literature with a diagnosis in the same spectrum. We found high scores on positive and manic psychotic symptoms and hostility, and low scores on guilt, depression, and negative symptoms. High scores on manic and psychotic symptoms are often accompanied by violent behavior. Low scores on guilt, depression, and negative symptoms could be indicative of externalizing coping skills. These characteristics could complicate treatment in the community and warrant further research along with clinical consideration.
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Cardoso, L. "Systematization of collection of relevant information about community maintenance treatment of people egress of psychiatric hospitalization." European Psychiatry 26, S2 (2011): 519. http://dx.doi.org/10.1016/s0924-9338(11)72226-x.

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In therapeutic advances context of mental care patients, community services are essential to maintenance treatment of people with severe mental disorders especially in people egress of psychiatric hospitalization cases. This research aim was to evaluate use of instruments to collect relevant information about maintenance treatment in a community mental health service.A two years quantitative and cross-sectional study developed in a community mental health service in Ribeirao Preto city- Sao Paulo - Brazil. The sample was egress patients and their family caregivers. It was utilizing a monthly nursing interview with following during six months with each patient and caregiver, to apply: sociodemographic and clinical questions; Structured Clinical Interview for Brief Psychiatric rating Scale (SIG-BPRS); Brief Psychiatric rating Scale (SIG-BPRS); Morisky-Green Adhesion Test; Family Burden Rating Scale (brazilian version - FIBS-BR).In this satudy participated 40 patients and 15 family caregivers. Between patients majority was women and diagnosis most prevalent was Schizophrenia and mood disorders. The psychiatric symptoms manifestation presents low degrees and medication adhesion treatment was low in 78% of patients. Family care givers was women in 96% of sample and 80% presents medium to high degrees of burden.The instruments utilized was important to evidence how patients and their caregivers was in maintenance of community treatment and collaborate to mental health professionals assistance systematization. The use of validated instruments can offer important information to mental health care in community services and maintenance treatments.
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Hwang, Ye In (Jane), Samuel Arnold, Julian Trollor, and Mirko Uljarević. "Factor structure and psychometric properties of the brief Connor–Davidson Resilience Scale for adults on the autism spectrum." Autism 24, no. 6 (2020): 1572–77. http://dx.doi.org/10.1177/1362361320908095.

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Resilience is an increasingly popular concept in literature as a protective factor against mental ill-health. While elevated rates of anxiety and mood disorders occur in adults on the autism spectrum, there is a gap in literature investigating the application of resilience to this population. This brief report examined the factor structure and psychometric properties of the 10-item Connor–Davidson Resilience Scale in a sample of 95 autistic adults ( Mage = 44). Our findings provide evidence for a unidimensional structure and robust psychometric properties of the scale in an autistic population, in line with factorial studies involving the general population. Lay Abstract Adults on the autism spectrum experience high rates of anxiety and depression, and may be particularly vulnerable to difficult and traumatic life experiences, which may contribute to the development and maintenance of these conditions. Resilience is an increasingly popular concept in research, which describes the ability to ‘bounce back’ following difficult emotional experiences, and the flexibility to adapt to stressful and demanding situations. The Connor–Davidson Resilience Scale has been used predominantly in studies involving non-autistic adults to measure resilience. While resilience is a potentially important concept for autistic adults, the suitability of the 10-item version of the Connor–Davidson Resilience Scale for use with adults on the spectrum has not yet been studied. In this short report, we investigate whether the Connor–Davidson Resilience Scale 10 is a valid measure to use with this population, and its relationship with other measures of mental well- or ill-being. Participants were 95 autistic adults with a mean age of 44 (63% female) who completed measures of resilience, autism symptoms, depression, anxiety and mental wellbeing. Overall, the findings indicate that the Connor–Davidson Resilience Scale 10 may be reliably used with autistic adults to measure trait resilience, which is associated with positive wellbeing and may serve as a protective factor from negative mental wellbeing. Future studies may use the Connor–Davidson Resilience Scale 10 to investigate resilience as a protective factor from negative mental health outcomes in response to traumatic and adverse emotional events for which autistic individuals may be particularly susceptible.
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CAVACO, SARA, ANA MARTINS da SILVA, ERNESTINA SANTOS, et al. "Are Cognitive and Olfactory Dysfunctions in Neuropsychiatric Lupus Erythematosus Dependent on Anxiety or Depression?" Journal of Rheumatology 39, no. 4 (2012): 770–76. http://dx.doi.org/10.3899/jrheum.110574.

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Objective.Depressed mood and cognitive impairments are common findings in systemic lupus erythematosus (SLE) and frequently coexist. We assessed the neuropsychological functioning of patients with SLE and investigated its association with psychopathological symptoms.Methods.A total of 85 patients with SLE (28 with neuropsychiatric syndromes: NPSLE) and 85 healthy control subjects with similar demographic characteristics were asked to perform a series of neuropsychological tests. A self-report questionnaire (the Hospital Anxiety and Depression Scale) was used to screen for psychopathology symptoms. Patients with SLE underwent a neurological examination.Results.Patients with NPSLE were more depressed and were more frequently impaired in cognitive and olfactory functions than controls or non-NPSLE patients. The NPSLE group remained statistically different from the other 2 groups on a series of neuropsychological measures (the Auditory Verbal Learning Test, Trail Making Test – Part A, Nine-Hole Peg Test, and Brief Smell Identification Test) even after control for elevated anxiety and depressed mood. Non-NPSLE and control groups were not significantly different regarding either psychopathological symptoms or neuropsychological functioning.Conclusion.Verbal memory, psychomotor speed, and olfaction are particularly vulnerable to dysfunction in NPSLE; impairment in these neuropsychological domains is not completely explained by psychopathology symptoms.
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Büssing, Arndt, Anemone Hedtstück, Sat Bir S. Khalsa, Thomas Ostermann, and Peter Heusser. "Development of Specific Aspects of Spirituality during a 6-Month Intensive Yoga Practice." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/981523.

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The majority of research on yoga focuses on its psychophysiological and therapeutic benefits, while the spiritual aspects are rarely addressed. Changes of specific aspects of spirituality were thus investigated among 160 individuals (91% women, mean age years; 57% Christians) starting a 2-year yoga teacher training. We used standardized questionnaires to measure aspects of spirituality (ASP), mindfulness (FMI—Freiburg Mindfulness Inventory), life satisfaction (BMLSS—Brief Multidimensional Life Satisfaction Scale), and positive mood (lightheartedness/relief). At the start of the course, scores of the respective ASP subscales forsearch for insight/wisdom, transcendence conviction, andconscious interactions/compassionwere high, while those forreligious orientationwere low. Within the 6 month observation period, bothconscious interactions/compassion(effect size, Cohen’s ),Religious orientation(),Lightheartedness/Relief() and mindfulness () increased significantly. Particularly non-religious/non-spiritual individuals showed moderate effects for an increase ofconscious interactions/compassion. The results from this study suggest that an intensive yoga practice (1) may significantly increase specific aspects of practitioners’ spirituality, mindfulness, and mood, (2) that these changes are dependent in part on their original spiritual/religious self-perception, and (3) that there are strong correlations amongst these constructs (i.e.,conscious interactions/compassion, and mindfulness).
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Niccols, Alison, Charles Cunningham, Peter Pettingill, Donna Bohaychuk, and Eric Duku. "Toddler mental health: The Brief Child and Family Intake and Outcomes System." International Journal of Behavioral Development 44, no. 6 (2019): 557–64. http://dx.doi.org/10.1177/0165025419880618.

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Despite the availability of effective early interventions, few toddlers with emotional and behavioral issues receive these services. This situation exists partly due to challenges in the identification of mental health issues in young children. We developed the Brief Child and Family Intake and Outcomes System for toddlers, which is a 36-item standardized online parent questionnaire including two externalizing scales (Cooperating; Regulating Attention, Impulsivity, and Activity), two internalizing scales (Expressing Emotion; Responding to Change), and two regulatory scales (Eating; Sleeping). We conducted a normative study of 500 Canadian children 18–36 months old, stratified by sex, age, geographic region, and parents’ marital status, income, and education. Confirmatory factor analyses demonstrated good model fit, and the relationship between items and scales did not vary significantly between boys and girls or between younger and older toddlers. Reliability estimates indicated high internal consistency. Providing preliminary evidence of validity, scale scores had positive relations with measures of family distress, caregiver mood, and demographic risk variables. Analyses of latent variables revealed good evidence of discriminant validity of the scales. We extend earlier work by including scales particularly relevant to toddler emotional and behavioral regulation while at the same time minimizing respondent burden and providing norms for Canadian toddlers. The questionnaire could be used in children’s mental health settings, primary care, child welfare, and daycare facilities, for intake, triage, and describing toddlers.
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Nahleh, Zeina A., Aleli Campbell, Rosalinda Heydarian, and Alok Kumar Dwivedi. "Effects of oral vitamin B12 for the treatment of aromatase inhibitors (AI)-related musculoskeletal symptoms in women with early stage breast cancer." Journal of Clinical Oncology 36, no. 7_suppl (2018): 86. http://dx.doi.org/10.1200/jco.2018.36.7_suppl.86.

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86 Background: Breast cancer patients receiving Aromatase Inhibitor (AI) therapy experience many side effects including arthralgias, myalgias and stiffness of joints. The objective of this study was to evaluate the effect of vitamin B12 supplements on pain related symptoms. Methods: In this study, patients taking AIs and experiencing pain at baseline were given 2500 mcg of vitamin B12 sublingually daily for 90 days. The validated Brief Pain Inventory-Short Form (BPI-SF) questionnaire using a 10 scale rating was evaluated prior and post- intervention. The BPI-SF asseses pain level and its interference with other daily life events on a scale from one to ten, one meaning pain does not interfere. Item 9 from the BPI assesses 7 important dimensions that are reported here. Results: 36 patients were recruited and scores were evaluated at baseline and at 90 days after taking vitamin B12 for general activity, mood, walking ability, normal work, relations with people, and for enjoyment of life post interventions as shown in the table. Conclusions: This study suggests that by taking a high dose of vitamin B12, significant improvement was observed in several dimensions related to pain scales in patients with AI -related musculoskeletal symptoms. Preliminary data confirms that vitamin B12 not only help improve pain, but it also aids in improving patient’s mood, well-being and relations with others. Larger randomized studies are warranted to confirm these promising findings. Clinical trial information: NCT03069313. [Table: see text]
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McLellan, Linda, Larry Foster, Lisa Rybicki, Jane Dabney, Michele Visnosky, and Brian Bolwell. "Predictive Value of the Psychosocial Assessment of Candidates for Transplantation (PACT) Scale in Allogeneic BMT." Blood 110, no. 11 (2007): 3330. http://dx.doi.org/10.1182/blood.v110.11.3330.3330.

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Abstract Purpose: Psychosocial risk factors have been reported to be associated with or predictive of treatment-related vulnerability and survival in allogeneic BMT. Recent survey research revealed that BMT clinicians consider psychosocial risk factors when making a decision whether or not to proceed with allogeneic BMT. The Psychosocial Assessment of Candidates for Transplantation (PACT) scale, a tool designed to study the psychosocial screening process and uniformity of decision-making in solid organ transplantation, has been utilized in BMT, but there is no research as to the relationship of the scores of psychosocial risk to medical outcomes, either in BMT or solid organ transplantation. This research analyzes the predictive value of PACT scale scores in relation to medical outcomes in allogeneic BMT. Methods: From 11/2003 to 6/2007, 120 allogeneic BMT patients were assessed pre-transplant by oncology social workers who subsequently completed the PACT scale. The PACT scale has ratings for social support, psychological health, lifestyle factors, and understanding of transplant and follow-up. Data analyses examined relationships between the overall PACT score of a patient (ranging from low to high risk) and post-transplant medical outcomes and baseline quality of life, mood states, and coping with illness; instruments utilized to measure the latter three psychosocial variables, in order, are the Functional Assessment of Cancer Therapy scale (FACT) specific to BMT, Profile of Mood States (brief form), and Brief COPE. Results: There is no significant relationship between risk scores on the PACT scale and shorter-term medical outcomes (i.e., length of stay, in-hospital death, death within 100 days, days until engraftment, and readmissions) nor longer-term medical outcomes (i.e., GVHD, relapse, overall survival, and relapse free survival). However, there is a significant relationship between the patient’s PACT score and pre-morbid psychosocial functioning. Lower risk PACT scores are associated with better quality of life; lower depression, anger, and confusion, higher vigor; and positive coping behaviors of self-distraction, positive reframing, and use of religion. Higher risk PACT scores are associated with negative coping behaviors of denial, substance use, and behavioral disengagement. Conclusions: Although the PACT scale as a measure of overall psychosocial risk has been promoted as a helpful tool for the pre-transplant psychosocial evaluation process, its’ predictive value with respect to medical outcomes in BMT is arguable. However, that PACT scores associated with pre-morbid psychosocial functioning underscores the utility of the PACT scale for screening a cluster of psychosocial issues that may combine as risk factors for treatment related vulnerability. Determining patient eligibility for BMT based on overall psychosocial risk is not advisable; needed is research to further study which specific psychosocial risk factors, if any, are associated with, if not prognostic of, medical outcomes.
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