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Relevant bibliographies by topics / Bromadiolone

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Academic literature on the topic 'Bromadiolone'

Author: Grafiati

Published: 4 June 2021

Last updated: 20 June 2025

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Journal articles on the topic "Bromadiolone"

1

Jokic, Goran, Sinisa Mitric, Dusan Pejin, et al. "Response of wild Mus musculus to baits containing essential oils: II bromadiolone and difenacoum baits with 0.75% cinnamon oil tested in storages." Pesticidi i fitomedicina 33, no. 3-4 (2018): 253–59. http://dx.doi.org/10.2298/pif1804253j.

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The effects of 0.75 % concentration of cinnamon essential oil on bait attractiveness and total biological efficacy of bromadiolone and difenacoum rodenticides to the house mouse were tested in practice. The experiments were conducted in storages with stable house mouse populations for which no resistance to anticoagulant rodenticides had been previously reported. A statistically significant difference was detected between bromadiolone and difenacoum baits. Consumption of bromadiolone baits supplemented with cinnamon essential oil was 74 % higher than the consumption of bromadiolone baits without cinnamon oil. The average efficacy of bromadiolone baits in controlling house mice was 96 %. Cinnamon essential oil added to difenacoum baits increased bait consumption by 39 %, i.e. it was 119 % higher than the consumption of oil-free baits. The average efficacy of difenacoum baits in controlling house mice was 99.5 %.

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2

Valverde, Irene, Silvia Espín, Pilar Gómez-Ramírez, et al. "Temporal Persistence of Bromadiolone in Decomposing Bodies of Common Kestrel (Falco tinnunculus)." Toxics 8, no. 4 (2020): 98. http://dx.doi.org/10.3390/toxics8040098.

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Bromadiolone is a second generation anticoagulant rodenticide (SGAR) used to control pest rodents worldwide. SGARs are frequently involved in secondary poisoning in rodent predators due to their persistence and toxicity. This study aims to evaluate the persistence of bromadiolone in liver at different stages of carcass decomposition in experimentally-dosed common kestrels (Falco tinnunculus) to understand the possibility of detecting bromadiolone in cases of wildlife poisoning and the potential risk of tertiary poisoning. Twelve individuals were divided into the bromadiolone-dose group (dosed with 55 mg/kg b.w) and the control group. Hepatic bromadiolone concentrations found in each stage of decomposition were: 3000, 2891, 4804, 4245, 8848, and 756 ng/g dry weight at 1–2 h (fresh carcass), 24 h (moderate decomposition), 72 h, 96 h (advanced decomposition), seven days (very advanced decomposition), and 15 days (initial skeletal reduction) after death, respectively. Liver bromadiolone concentrations in carcasses remained relatively stable over the first four days and raised on day 7 of decomposition under the specific conditions of this experiment, presenting a risk of causing tertiary poisoning. However, at the initial skeletal reduction stage, liver bromadiolone concentration declined, which should be considered to interpret toxicological analyses and for proper diagnosis. This experimental study provides for the first time some light to better understand the degradation of SGARs in carcasses in the wild.

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Lee, Kuan-I., Jing-Hua Lin, Yen-Jung Chu, Jou-Fang Deng, Wei-Lan Chu, and Dong-Zong Hung. "Rat Bait, Not Healthy Rice!" Toxics 11, no. 1 (2023): 60. http://dx.doi.org/10.3390/toxics11010060.

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Bromadiolone, a potent, long-acting anticoagulant rodenticide is frequently tinted to a red or pink color and mixed with cereals as rat bait. Six peoples working in a small factory suffered from a severe bleeding tendency several weeks after consuming a rice meal that was tainted with bromadiolone mistaken to be healthy food. High serum levels of bromadiolone and excessive bleeding were found in these individuals, and they needed vitamin K1 therapy for weeks. These cases indicated that long-acting anticoagulant rodenticide might induce cumulative toxicity in repeated, low-dose exposure, and the blood levels of bromadiolone might be an indicator for antidote therapy if available.

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Munusamy, Baskar, Devi Anju, and Arya Bharti. "Identification and Conformation of Bromadiolone Using HPLC and Molecular Dynamics Simulations." International Journal of Current Science Research and Review 04, no. 10 (2021): 1457–64. https://doi.org/10.47191/ijcsrr/V4-i10-30.

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Abstract : Rodenticides of warfarin group are mainly consisting of bromadiolone(3-(3-(4′-bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl)-4-hydroxycoumarin), 3-bromofuran, zinc phosphide etc., having different chemical composition which are frequently used for attempting suicide, perpetrating homicide, accidental inhalation of human being while baiting rats, birds, rabbits in agricultural fields. Bromadiolone, strong and long-acting rodenticide, having anticoagulant properties and also acting as antagonist by disrupting the normal blood clotting mechanisms to vitamin-K, required for blood clotting, and increasing the bleeding tendency in rodents has been taken for finding its reaction mechanisms with different solvent media. The main symptoms of the bromadiolone rodenticides are dizziness, unsteady gait, and abnormal behavior. In the present study, we focused to determine the presence of Bromadiolone in ppm level using HPLC, the reaction mechanism of functional groups (ketone, alcohol, phenol) present in the bromadiolone under the solvent media such as H2O and HCl. The software, Avogadro, has been used to dynamically simulate the Bromadiolone for calculating its optimum energy and to conform the molecular structure under the influence of the water molecule. The reaction mechanism of functional groups in the bromadiolonecombined with the MD simulations may through light to reveal the enzymes activity in damaging the central nervous system which led to fatal.

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5

Enouric, Saad, Kristina Dekroon, Robert Friendship, Nick Schrier, Patricia Dowling, and Ron Johnson. "Depletion of bromadiolone in tissues of hogs following oral exposure." Journal of Swine Health and Production 23, no. 6 (2015): 298–305. http://dx.doi.org/10.54846/jshap/898.

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Objectives: To assess bromadiolone depletion in the edible tissues of swine and propose post-exposure withdrawal periods. Materials and methods: Two groups of barrows and two groups of gilts were given a single oral dose of bromadiolone: low dosage (LD, 0.05 mg/kg; n = 20; 10 males, 10 females) and high dose (HD, 0.5 mg/kg; n = 20; 10 males, 10 females). Coagulation parameters were assessed before and after administration. Animals were sacrificed at 1, 2, 3, 5, and 6 weeks (LD) and 1, 2, 3, 6, and 9 weeks (HD) post dosing. Loin muscle, skin-adherent fat, liver, feces, and blood were analyzed for bromadiolone using liquid chromatography-tandem mass spectrometry. Results: Partial thromboplastin times exceeded control values in the LD and HD groups 6 and 9 weeks post dosing, respectively. In the HD group, bromadiolone concentrations exceeded the limit of detection (LOD) at all time points in liver and skin-adherent fat and for up to 6 weeks in feces, muscle, and plasma. In the LD group, bromadiolone concentrations exceeded the LOD at all time points in liver and up to 3 weeks in fat, feces, and plasma. Estimated withdrawal periods for bromadiolone in liver were 83 and 176 weeks in the LD and HD groups, respectively, and 62 weeks in muscle in the HD group. Implication: Bromadiolone residues persist in tissues such that it is impractical to wait for the hog to eliminate the rodenticide to a concentration that is safe for entry into the human food chain.

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6

Grobosch, T., B. Angelow, L. Schonberg, and D. Lampe. "Acute Bromadiolone Intoxication." Journal of Analytical Toxicology 30, no. 4 (2006): 281–86. http://dx.doi.org/10.1093/jat/30.4.281.

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7

Babich, N. V. "Effectiveness of rodenticides based on bromadiolone against the common vole Microtus arvalis Pall. in laboratory conditions." Агрохимия, no. 1 (January 15, 2024): 26–32. http://dx.doi.org/10.31857/s0002188124010042.

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The number of preparations based on the 2nd generation anticoagulant bromadiolone in the catalog of plant protection products against mouse-like rodents in Russia is growing, but information about the effectiveness of this active substance against the common vole Microtus arvalis Pall. is very limited. In a laboratory study of bromadiolone, acute LD50 = 3.3 + 0.8 mg/kg was shown, increased resistance equal to LD50 5.2 mg/kg was detected in individuals selected on the basis of resistance to anticoagulants of the 1st generation against the background of a diet with a high content of vitamin K (green food). Rodents overcame relative stability in the laboratory with a 3-day consumption of bait (0.05 g of bromadiolone/kg). In the field, the effectiveness of treatments may decrease and lead to the selection of resistant individuals. Bromadiolone-based rodenticidal baits are suitable for controlling the number of mouse-like rodent communities with the dominance of the common vole and carrying out treatments at the beginning of population growth.

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8

Deepa, Subbiah, and Ashok K. Mishra. "Fluorescence spectroscopic study of serum albumin–bromadiolone interaction: fluorimetric determination of bromadiolone." Journal of Pharmaceutical and Biomedical Analysis 38, no. 3 (2005): 556–63. http://dx.doi.org/10.1016/j.jpba.2005.01.023.

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9

Fourel, Isabelle, Marlène Damin-Pernik, Etienne Benoit, and Virginie Lattard. "Cis-bromadiolone diastereoisomer is not involved in bromadiolone Red Kite ( Milvus milvus) poisoning." Science of The Total Environment 601-602 (December 2017): 1412–17. http://dx.doi.org/10.1016/j.scitotenv.2017.06.011.

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10

De Araújo, Gabriel Rios, Maria Carolina Ricciardi Sbizera, Marcela Lucas De Lima, et al. "Avaliação da Palatabilidade e da Resistência de Diferentes Rodenticidas Disponíveis para Uso por Empresas Especializadas, em Aviários no Município de Rolândia, Paraná." UNICIÊNCIAS 21, no. 1 (2017): 2. http://dx.doi.org/10.17921/1415-5141.2017v21n1p2-6.

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A presença de roedores em estabelecimentos gera importantes prejuízos financeiros, além de representar risco à saúde animal e humana, fazendo-se necessário o seu controle. O trabalho teve como objetivo testar produtos rodenticidas disponíveis para o uso profissional quanto à aceitação pelos roedores e a sua resistência às ações ambientais. Foram utilizados três rodenticidas anticoagulantes de dose única; Brodifacum Bloco Parafinado (Syngenta®); Difetialona Bloco Extrusado (Bayer®); e Bromadiolone Bloco Extrusado (De Sangosse®). Os rodenticidas foram acondicionados em porta-iscas distribuídos em quatro aviários de uma granja produtora de aves de corte, no município de Rolândia, PR. Semanalmente, foi anotada a quantidade consumida e a deterioração dos rodenticidas. Os resultados obtidos nas quatro semanas mostram que na situação testada, o Brodifacum representa 68,3% do total de blocos consumidos, o Difetialona 26,7% e o Bromadiolone 5%. Em relação à resistência às ações ambientais, o Bromadiolone teve 19 blocos afetados (23,2%), o Difetialona 30 blocos (36,6%) e o Brodifacum 33 blocos (40,2%), tanto o consumo quanto a resistência entre os blocos não foram significativas estatisticamente. Os dados evidenciam que a escolha do rodenticida tem influência direta na eficiência, devendo ser um quesito valorizado no planejamento das ações de controle de roedores.Palavras-chave: Controle de Roedores. Rodenticida. Aceitação de Rodenticida.AbstractThe presence of rodents in establishments generates significant financial losses, as well as it poses a risk to animals and human’s health, making its control necessary. The study aimed to test rodenticides products available for professional use regarding the rodents’ acceptance and their resistance to environmental actions. Three single dose anticoagulant rodenticides wereused; Brodifacum Block waxed (Syngenta™); Difethialone Block Extruded (Bayer™); and Bromadiolone Block Extruded (De Sangosse™). Rodenticides were placed in bait holders distributed in four aviaries producing broilers in Rolândia city, PR. Thee amount consumed and the deterioration of rodenticides were weekly noted. The results obtained in four weeks show that in the tested situation, Brodifacum represents 68.3% of total consumed blocks, Difethialone 26,7% and Bromadiolone 5%. For resistance to environmental actions, Bromadiolone had 19 blocks affected (23.2%), Difetialona 30 blocks (36.6%) and Brodifacum 33 blocks (40.2%), both consumption and the resistance amongthe blocks were not statistically significant. The data show that the choice of rodenticide directly influences the efficiency and should be a question valued in the planning of rodent control measures.Keywords: Rodent control. Rodenticide. Rodenticides Acceptance.

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Dissertations / Theses on the topic "Bromadiolone"

1

Nahas, Kamil. "Cinétique et métabolisme de la bromadiolone, rodonticide anticoagulant, chez Rattus norvegicus, souche sauvage." Lyon 1, 1987. http://www.theses.fr/1987LYO1T028.

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2

Nahas, Kamil. "Cinétique et métabolisme de la bromadiolone, rodonticide anticoagulant, chez Rattus norvegicus, souche sauvage." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37608317v.

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3

Sage, Mickaël. "Transfert de bromadiolone (appâts/sols – campagnols de prairie – renards) : Etude environnementale de la persistance et mesure indirecte de l'exposition." Phd thesis, Université de Franche-Comté, 2008. http://tel.archives-ouvertes.fr/tel-00404261.

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Depuis les années 50, les rodenticides anticoagulants sont couramment utilisés pour contrôler les populations de rongeurs commensaux et de prairie. De nombreux empoisonnements de la faune non cible sont répertoriés partout dans le monde. En Europe de l'Ouest notamment, la bromadiolone est utilisée de façon intensive dans les champs. Elle est le seul rodenticide autorisé en France pour contrôler les populations de Campagnol terrestre, Arvicola terrestris Sherman. Ces opérations utilisant des appâts grains de blé enterrés dans le sol sont réalisées à de larges échelles et des dizaines voire des centaines d'empoisonnements secondaires de prédateurs, dont le renard, sont répertoriés chaque année. Cette étude propose d'apporter des éléments de compréhension sur les modalités de son transfert à travers les systèmes biologiques complexes considérés dans leur intégralité.<br />Le premier objectif a été d'évaluer la variabilité environnementale de la persistance de la bromadiolone dans les appâts en conditions naturelles. Cette persistance dans les galeries de traitement est courte (demi-vie de 3 à 6 jours) et faiblement influencée par les conditions environnementales (type de sol et conditions climatiques). Cependant, elle augmente considérablement lors du stockage des appâts dans des réserves (27

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4

Morin, Marie-Françoise. "Etude de l'impact sur le milieu naturel de la bromadiolone, rodonticide anticoagulant : évolution en milieu aqueux et bioaccumulation sur des organismes terrestres et aquatiques." Poitiers, 1988. http://www.theses.fr/1988POIT2315.

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Morin, Marie-Françoise. "Etude de l'impact sur le milieu naturel de la bromadiolone, rodonticide anticoagulant évolution en milieu aqueux et bioaccumulation sur des organismes terrestres et aquatiques /." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb376166747.

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6

Pereira, Francisca Lopes Sendas. "Incidência de rodenticidas em aves de rapina: estudo de prevalência e possíveis efeitos secundários." Bachelor's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2010. http://hdl.handle.net/10400.5/1803.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>O impacto dos rodenticidas na fauna selvagem, principalmente os anticoagulantes de segunda geração representados pelo Brodifacume e Bromadiolona, foram e são causa de inúmeros envenenamentos primários e secundários, através de ingestão directa ou pela ingestão de animais envenenados. Alguns estudos sugerem que a exposição a doses sub-letais destes xenobióticos podem causar uma morte “indirecta”, devido a uma predisposição a diferentes tipos de trauma ou outras patologias. Neste estudo, é valorada a possível relação entre a presença/ausência destes pesticidas anticoagulantes em animais e outras lesões indirectamente relacionadas com uma intoxicação sub-letal. A população estudada foram todas as aves de rapina que ingressaram num centro de recuperação em Madrid, Espanha, como cadáveres ou que morreram ou foram eutanasiadas durante o seu tratamento, devido à severidade das lesões. Foi utilizado o fígado destas aves para a análise toxicológica mediante a metodologia de Cromatografia de Camada Fina (TLC) com detecção por luz UV. Vinte das cinquenta e três aves analisadas foram positivas a estes compostos e a Bromadiolona foi detectada em 80% dos casos. Foram encontradas relações importantes entre esta positividade e algumas varáveis analisadas como certas lesões visualizadas à necrópsia e baixa condição corporal. Também foi encontrada uma relação positiva entre os animais com resíduos de rodenticida no seu organismo e a causa de ingresso, sendo o trauma contra estrutura a mais significativa.<br>ABSTRACT - RODENTICIDE INCIDENCE IN BIRDS OF PREY: PREVALENCE STUDY AND POSSIBLE SECONDARY EFFECTS - The impact of rodenticides in the wildlife, mainly the second generation anticoagulant represented by Brodifacoum and Bromadiolone, has caused and still causes innumerous cases of primary and secondary poisoning, by direct ingestion or by ingestion of poisoned animals. Some studies suggest that exposition to sub-lethal doses of theses xenobiotics could cause an “indirect” fatality, due to a bigger predisposition to different kinds of trauma or other pathology. In this study, its assess the possible relation between the presence/absence of anticoagulant pesticides in animals and other injuries not directly related with a sub lethal intoxication present in those animals. The sample population in study was all the birds of prey that had entered in a rehabilitation centre of Madrid, Spain, already dead or that had been dead or sacrificed during the treatment, due to the severity of injuries. A thin layer chromatography (TLC) methodology has been used with UV light detection in the toxicological analysis of the liver of these birds. Twenty of the fifty-three analyzed birds were positive to this compounds and Bromadiolone was found in 80% of the cases. Important relations were found between positive animals and some necropsy findings and poor body condition. It was also found a positive relation between the positive animals and the cause of injury, being the trauma against structure the most significant.

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Books on the topic "Bromadiolone"

1

Sullivan, Daniel. Use of bromadiolone for control of the Columbian ground squirrel. Montana Dept. of Agriculture, Environmental Management Division, Technical Services Bureau, 1987.

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2

Sullivan, Daniel. Efficacy of bromadiolone and strychnine baits for control of the northern pocket gopher. Montana Dept. of Agriculture, Environmental Management Division, Technical Services Bureau, 1987.

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3

Bromadiolone Health and Safety Guide (Health & Safety Guide: 94). World Health Organization, 1995.

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Book chapters on the topic "Bromadiolone"

1

Rao, K. S. "Bromadiolone." In Encyclopedia of Toxicology. Elsevier, 2005. http://dx.doi.org/10.1016/b0-12-369400-0/00150-2.

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2

Tarazona, Jose V. "Bromadiolone." In Reference Module in Biomedical Sciences. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-12-824315-2.00716-8.

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3

Unger, Thomas A. "Bromadiolone." In Pesticide Synthesis Handbook. Elsevier, 1996. http://dx.doi.org/10.1016/b978-081551401-5.50653-5.

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4

Ramasahayam, S. "Bromadiolone." In Encyclopedia of Toxicology. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-386454-3.00367-5.

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