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Journal articles on the topic 'Bromocresol green(BCG)'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Delanghe, Sigurd, Wim Van Biesen, Nadeige Van de Velde, et al. "Binding of bromocresol green and bromocresol purple to albumin in hemodialysis patients." Clinical Chemistry and Laboratory Medicine (CCLM) 56, no. 3 (2018): 436–40. http://dx.doi.org/10.1515/cclm-2017-0444.

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AbstractBackground:Colorimetric albumin assays based on binding to bromocresol purple (BCP) and bromocresol green (BCG) yield different results in chronic kidney disease. Altered dye binding of carbamylated albumin has been suggested as a cause. In the present study, a detailed analysis was carried out in which uremic toxins, acute phase proteins and Kt/V, a parameter describing hemodialysis efficiency, were compared with colorimetrically assayed (BCP and BCG) serum albumin.Methods:Albumin was assayed using immunonephelometry on a BN II nephelometer and colorimetrically based on, respectively,

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Wells, F. E., G. M. Addison, and R. J. Postlethwaite. "Albumin Analysis in Serum of Haemodialysis Patients: Discrepancies between Bromocresol Purple, Bromocresol Green and Electroimmunoassay." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 22, no. 3 (1985): 304–9. http://dx.doi.org/10.1177/000456328502200314.

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The analysis of serum albumin by bromocresol purple (BCP), by bromocresol green (BCG), and by electroimmunoassay (EIA) has been compared in a mixed group of 100 hospital patients. Good agreement between the immunochemical and BCP methods, but a positive bias with the BCG method led to routine use of the BCP method. In a group of 19 paediatric patients on chronic haemodialysis the mean BCP-albumin was found to be lower than the true albumin, as determined by EIA, whereas the positive bias using the BCG method remained. The difference between BCP-albumin and EIA-albumin in the haemodialysis grou

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Mohamed, Mona A., Nada S. Abdelwahab, and Craig E. Banks. "Electroanalytical sensing of the antimicrobial drug linezolid utilising an electrochemical sensing platform based upon a multiwalled carbon nanotubes/bromocresol green modified carbon paste electrode." Analytical Methods 8, no. 22 (2016): 4345–53. http://dx.doi.org/10.1039/c6ay00454g.

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4

Saiyed, Samar Ashfaq, Preeti Jadeja, and Rajashree Mashru. "Development and Validation of Extractive Spectrophotometric Methods for the Estimation of Telmisartan by Using Smartphone Application." Journal of Drug Delivery and Therapeutics 12, no. 3-S (2022): 178–90. http://dx.doi.org/10.22270/jddt.v12i3-s.5527.

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Two simple, sensitive, accurate, precise and reproducible extractive colorimetric methods were developed for estimation of Telmisartan in bulk and pharmaceutical dosage form. These methods are based on the formation of colored ion-pair complex of Telmisartan with Bromocresol green (BCG) and Bromocresol purple (BCP) dyes in acidic medium. The complex was extracted in chloroform and estimated quantitatively at 421 nm and 411 nm for BCG and BCP dyes respectively. For estimation of TMS present in the sample, estimation was also done by using Smartphone Application known as PhotoMetrix Pro. Beer La

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5

Bai, Hongmei, Ping He, Jingchao Chen, et al. "Electrocatalytic degradation of bromocresol green wastewater on Ti/SnO2-RuO2 electrode." Water Science and Technology 75, no. 1 (2016): 220–27. http://dx.doi.org/10.2166/wst.2016.509.

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Thermal decomposition method was employed to prepare a Ti/SnO2-RuO2 electrode, on which electrocatalytic degradation of bromocresol green (BCG) was investigated in detail. Scanning electron microscopy, an X-ray diffraction analyzer and an X-ray fluorescence spectrometer were adopted to characterize the morphology, crystal structure and element analysis of the as-prepared Ti/SnO2-RuO2 electrode. It was indicated that the Ti/SnO2-RuO2 electrode had a ‘cracked-mud’ structure and exhibited a superior specific surface area. The removal efficiency of BCG on the Ti/SnO2-RuO2 electrode was determined

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6

Hải, Nguyễn Thị Thanh, та Nguyễn Hoàng Phương. "Ảnh hưởng của điều trị heparin đến xét nghiệm định lượng albumin huyết tương bằng phương pháp Bromocresol Green". Tạp chí Nghiên cứu Y học 182, № 9 (2024): 1–8. http://dx.doi.org/10.52852/tcncyh.v182i9.2640.

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Nghiên cứu mô tả đánh giá độ chênh lệch của hai phương pháp xét nghiệm albumin BCG (Bromocresol Green) và BCP (Bromocresol Purple) trên mẫu huyết tương của bệnh nhân có hoặc không điều trị heparin. Nghiên cứu thực hiện so sánh kết quả định lượng albumin trên 272 mẫu bệnh nhân có hoặc không điều trị heparin bằng cả 2 phương pháp BCG và phương pháp tham chiếu BCP là phương pháp không bị nhiễu bởi heparin. Kết quả nồng độ albumin định lượng bằng phương pháp BCG trung bình cao hơn phương pháp BCP 15,1% (95%CI: 13,3% - 16,8%). Trong đó, mẫu bệnh nhân có sử dụng heparin trung bình chênh lệch giữa ha

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7

Seelmann, Katharina, Martha Gledhill, Steffen Aßmann, and Arne Körtzinger. "Impact of impurities in bromocresol green indicator dye on spectrophotometric total alkalinity measurements." Ocean Science 16, no. 2 (2020): 535–44. http://dx.doi.org/10.5194/os-16-535-2020.

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Abstract. Due to its accurate and precise character, spectrophotometric pH detection is a common technique applied in measurement methods for carbonate system parameters. However, impurities in the used pH indicator dyes can influence the measurements quality. During our work described here, we focused on impacts of impurities in the pH indicator dye bromocresol green (BCG) on spectrophotometric seawater total alkalinity (AT) measurements. In order to evaluate the extent of such influences, purified BCG served as a reference. First, a high-performance liquid chromatography (HPLC) purification

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8

Shah, Kamal, Alka Gupta, and Pradeep Mishra. "Extractive Spectrophotometric Methods for the Determination of Etoricoxib in Tablets." E-Journal of Chemistry 6, no. 1 (2009): 207–12. http://dx.doi.org/10.1155/2009/280961.

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Two simple, rapid, sensitive, precise and economic spectrophotometric methods have been developed for the estimation of etoricoxib in tablet formulation. During the course of study, it was observed that acidic solution of the drug formed colored ion-association complexes with Bromocresol Green (BCG) and Bromocresol Purple (BCP) which were soluble in chloroform. This property of the drug was followed for the development of colorimetric methods for analysis of drug. The complex of etoricoxib with BCG and BCP showed λmax at 416 nm and 408 nm respectively. These methods were validated statisticall

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9

Samanta, Subhodip. "Effect of Isopropanol Mixed Solvent on Interaction of Cetyltrimethylammonium Bromide with Bromocresol Green: A Conductometric Study." Asian Journal of Chemistry 36, no. 4 (2024): 811–20. http://dx.doi.org/10.14233/ajchem.2024.31216.

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In present work, the interaction of an anionic dye, bromocresol green (BCG) with a cationic surfactant, cetyltrimethylammonium bromide (CTAB), was studied using conductometric method. The effect of alteration of solvent media from water to cosolvent isopropanol and the effect of elevation in experimental temperature on the association behaviour of BCG-CTAB system were studied. The observed CMC and ΔG°m values indicate disfavored micellization of CTAB system in isopropanol. Whereas micellization of CTAB is favoured in the presence of BCG as additive. For BCG-CTAB system micellization becomes mo

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10

P, PoojaShree, Senthil Kumar G P, Chaithra R, Vidya D N, Bhadresh D R, and Manojkumar S. "Validated extractive analytical methods for the estimation of pregabalin in bulk and pharmaceutical dosage form." International Journal of Advanced Chemistry 8, no. 1 (2020): 22. http://dx.doi.org/10.14419/ijac.v8i1.30273.

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Two simple, rapid, sensitive and accurate spectrophotometric methods are described for the determination of Pregabalin (PRG) in bulk and pharmaceutical formulations. The methods are based on the reactions of the drug with bromocresol purple (BCP) and bromocresol green (BCG) in buffered hydrochloric acid solutions at pH 1.2 to give coloured ion-pair complexes extractable with chloroform. The coloured products are quantitated spectrophotometrically at 431 nm with BCP and 444.80 nm with BCG. Beer's law is obeyed in the concentration range 10-50 µg/ml with both reagents. Recovery studies gave sati

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11

Ying, Yuet Lee, Swee Yong Pung, Ming Thong Ong, and Yuk Fen Pung. "A Comparison Study between ZnO Nanorods and WO₃/ZnO Nanorods in Bromocresol Green Dye Removal." Solid State Phenomena 264 (September 2017): 87–90. http://dx.doi.org/10.4028/www.scientific.net/ssp.264.87.

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This work studied the photocatalytic performance of ZnO nanorods and WO3/ZnO nanorods in bromocresol green (BCG). The ZnO nanorods were pre-synthesized via solution precipitation method. Subsequently, the nanorods were kept in sodium tungstate solution for the deposition of WO3. The present of WO3 was confirmed by XRD and EDX analysis. ZnO nanorods (64.34%) showed a higher photodegradation efficiency of BCG removal than WO3/ZnO nanorods (60.03%) under 75 minutes of UV irradiation. This could be attributed to the formation of WO3/ZnO shell-core nanostructure which limited the generation of hole

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12

Zhang, Chenxi, Lingbin Meng, Zhihao Fang, et al. "Experimental and Theoretical Studies on the Adsorption of Bromocresol Green from Aqueous Solution Using Cucumber Straw Biochar." Molecules 29, no. 19 (2024): 4517. http://dx.doi.org/10.3390/molecules29194517.

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Biochar prepared from crop straw is an economical method for adsorbing bromocresol green (BCG) from textile industrial wastewater. However, there is limited research on the adsorption mechanism of biochar for the removal of BCG. This study utilized cucumber straw as raw material to prepare biochar with good adsorption potential and characterized its physicochemical properties. Through adsorption experiments, the effects of solution pH, biochar dosage, and initial dye concentration on adsorption performance were examined. The adsorption mechanism of cucumber straw biochar (CBC) for BCG was eluc

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13

Gainza, Alberto Hernandez, and Roy Ikemefula Konyeaso. "Substitution reactions of benzethonium chloride with ion associates of bromocresol green – quinine and bromophenol blue – quinine in dichloromethane." Canadian Journal of Chemistry 69, no. 6 (1991): 937–44. http://dx.doi.org/10.1139/v91-139.

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An excess concentration of base quinine (Q) reacts with a sulphonphthalein diacidic dye XH2, (bromocresol green, BCGH2, or bromophenol blue, BPBH2) in dichloromethane solution to form an ion associate (X2−(QH+)2) of stoichiometry 1:2 (dye:amine). Benzethonium chloride (ClB) reacts with the 1:2 ion associate to form an ion associate (QH+,X2−,B+) and quinine hydrochloride ClQH+. This substitution reaction is a chemical equilibrium with formation constants of 1.50 ± 0.67, 1.61 ± 0.54, 1.07 ± 0.29, 1.04 ± 0.20, and 0.84 ± 0.26 for BCG and 1.86 ± 0.59, 1.47 ± 0.23, 1.40 ± 0.65, 1.13 ± 0.37, and 1.1

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14

Gouda, Ayman A., Alaa S. Amin, Ragaa El-Sheikh, and Amira G. Yousef. "Spectrophotometric Determination of Gemifloxacin Mesylate, Moxifloxacin Hydrochloride, and Enrofloxacin in Pharmaceutical Formulations Using Acid Dyes." Journal of Analytical Methods in Chemistry 2014 (2014): 1–16. http://dx.doi.org/10.1155/2014/286379.

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Simple, rapid, and extractive spectrophotometric methods were developed for the determination of some fluoroquinolones antibiotics: gemifloxacin mesylate (GMF), moxifloxacin hydrochloride (MXF), and enrofloxacin (ENF) in pure forms and pharmaceutical formulations. These methods are based on the formation of ion-pair complexes between the basic drugs and acid dyes, namely, bromocresol green (BCG), bromocresol purple (BCP), bromophenol blue (BPB), bromothymol blue (BTB), and methyl orange (MO) in acidic buffer solutions. The formed complexes were extracted with chloroform and measured at 420, 40

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15

Khashaba, Pakinaz Y., Hassan Refat H. Ali, and Mohamed M. El-wekil. "Development of a novel and cost-effective redox sensor for voltammetric determination of pantoprazole sodium during pharmacokinetic studies." Royal Society Open Science 4, no. 8 (2017): 170324. http://dx.doi.org/10.1098/rsos.170324.

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A pencil graphite electrode modified with poly (bromocresol green (BCG)) was prepared by electro-polymerization process for the determination of pantoprazole sodium. The surface morphology and structure of poly (BCG) film were characterized by scanning electron microscopy and Fourier transform infrared spectroscopy. The determination of pantoprazole sodium in Britton–Robinson buffer (pH 7.0) was carried out by square wave adsorptive stripping voltammetric technique. Under optimum conditions, the linear response of the peak with concentration of the cited drug was in the range of 6.6–360 × 10 −

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Dr.L.Satyanarayana*, and T.Padmini. "SPECTROPHOTOMETRIC DETERMINATION OF AMPRENAVIR IN FORMULATION SAMPLE." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 2204–8. https://doi.org/10.5281/zenodo.838700.

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A validate rapid, economical and sensitive visible spectrophotometric method has been developed for quantitative determination of amprenavir in bulk drug and tablet samples.This method is validated for irinotecan with chromogenic reagent namely bromo cresol green (BCG) at λ max 417. The calibration curve was linear over a concentration range of 5-40 µg/ml. The relative standard deviation (R.S.D) is less than 1% and average recovery was above 99.60%. Efficient visible spectrophotometric detection at λmax 417nm enabled determination of the drug with no interference from tablet excipients. The pr

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17

El Defrawy, Ahmed Mohamed, and Amr Lotfy Saber. "Spectrophotometric and theoretical studies on the determination of etilefrine hydrochloride in pharmaceutical formulations and biological samples." Tropical Journal of Pharmaceutical Research 16, no. 10 (2017): 2487–500. http://dx.doi.org/10.4314/tjpr.v16i10.24.

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Purpose: To develop a simple and cost effective spectrophotometric method for the determination of etilefrine hydrochloride (ET) in pharmaceutical formulations and human plasma.Methods: The method is based on extraction of ET into chloroform as ion-pair complexes with bromocresol green (BCG) and methyl orange (MO) in acidic medium. The interaction of ET with BCG and MO reagents were investigated using B3LYP/6-31G(d) level of theory. The geometrical parameters of the interacting species and the ion pairs formed were characterized based on their frontier molecular orbitals, atomic charges, elect

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18

Naz, Asma, Sundus Khan, Aqsa Sajjad, et al. "Unveiling Synergistic Bonds: Exploring Spectroscopic Interactions between Tween 20 and Bromocresol Green for Enhanced Applications." Journal of Health and Rehabilitation Research 4, no. 1 (2024): 836–42. http://dx.doi.org/10.61919/jhrr.v4i1.525.

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Background: Surfactants and dyes interact in ways that can significantly alter the optical properties of solutions, a phenomenon with broad implications across various scientific fields, including healthcare. Understanding these interactions, especially in aqueous environments, is crucial for developing advanced diagnostic tools and enhancing drug delivery systems. Objective: This study aimed to investigate the interactions between the non-ionic surfactant Tween 20 and the dye Bromocresol Green (BCG) in aqueous solutions. By elucidating these interactions, the research sought to explore the po

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Zhang, Zhepeng, Haiqing Tang, Keyan Cai, Ruiping Liang, Li Tong, and Changrong Ou. "A Novel Indicator Based on Polyacrylamide Hydrogel and Bromocresol Green for Monitoring the Total Volatile Basic Nitrogen of Fish." Foods 12, no. 21 (2023): 3964. http://dx.doi.org/10.3390/foods12213964.

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An intelligent indicator was developed by immobilizing bromocresol green (BCG) within the polyacrylamide (PAAm) hydrogel matrix to monitor the total volatile basic nitrogen (TVB-N) content of fish. The FTIR analysis indicated that BCG was effectively incorporated into the PAAm through the formation of intermolecular hydrogen bonds. A thermogravimetric analysis (TGA) showed that the PAAm/BCG indicator had a mere 0.0074% acrylamide monomer residue, meanwhile, the addition of BCG improved the thermal stability of the indicator. In vapor tests with various concentrations of trimethylamine, the ind

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Aba, La, Yusril Yusuf, Mitrayana, Dwi Siswanta, Junaidi, and Kuwat Triyana. "Sensitivity Improvement of Ammonia Gas Sensor Based on Poly(3,4-ethylenedioxythiophene):Poly(styrenesulfonate) by Employing Doping of Bromocresol Green." Journal of Nanotechnology 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/864274.

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The aim of this research is to improve the sensitivity of ammonia gas sensor (hereafter referred to as sensor) based on poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) by employing the doping dye of bromocresol green (BCG). The doping process was carried out by mixing the BCG and the PEDOT:PSS in a solution with an optimum ratio of 1 : 1 in volume. The sensor was fabricated by using spin-coating technique followed by annealing process. For comparison, the BCG thin film and the PEDOT:PSS thin film were also deposited with the same method on glass substrates. For optical char

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Filípek, Jaroslav, and Josef Illek. "Serum albumin assay – easy or problematic analysis?" Acta Veterinaria Brno 89, no. 4 (2020): 301–5. http://dx.doi.org/10.2754/avb202089040301.

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Serum albumin determination is an important biochemical investigation in clinical laboratories. Photometric methods using albumin binding to organic dyes – bromocresol green (BCG) or bromocresol purple (BCP) – are most commonly used. These determinations are quick, simple, and inexpensive. They are, however, associated with a number of problems. Discussions on the methodological unification and use of BCP are ongoing in human laboratory medicine. The reaction of human albumin with this dye is more specific. On the other hand, its affinity for animal albumin is significantly lower, for which re

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22

Mohamed, Sabrein H., Alyaa I. Magdy, and Ashour A. Ahmed. "Exploring the nature of the clopidogrel–bromocresol green interactionviaspectrophotometric measurements and quantum chemical calculations." RSC Advances 8, no. 51 (2018): 29104–14. http://dx.doi.org/10.1039/c8ra05187a.

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The nature of the different electronic transitions of clopidogrel bisulfate; antiplatelet agent, in BCG ion-pair and quantitative analysis based on extracting a yellow-formed ion-pair into chloroform from aqueous medium is obtained.

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23

Gaínza, Alberto Hernández. "Associations of ajmaline and homatropine with bromocresol green and bromophenol blue in dichloromethane: thermodynamic and kinetic parameters." Canadian Journal of Chemistry 65, no. 6 (1987): 1279–91. http://dx.doi.org/10.1139/v87-215.

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Ajmaline (AJ) and homatropine (HM) react with bromocresol green (BCG) and bromophenol blue (BPB) in dichloromethane forming 1:1 and 1:2 ion pairs clearly in a chemical equilibrium. Thermodynamic parameters ΔG0, ΔH0, and ΔS0 are calculated using the Van't Hoff equation. In a large excess of HM a product P is formed from the 1:2 ion pair in a pseudo-first order kinetic process which fits Arrhenius' equation. The P product has been identified as a type of charge transfer complex. The thermodynamic parameters corresponding to the formation of the ion pairs BPB—(AJ)2, BCG—(AJ)2, BPB—(HM)2, and BCG—

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24

Abdalla, Shalaby, El-Maamly Magda, M. Abdel-Gawad Fatma, M. Azab Shereen, and S. Eldin Amira. "Spectrophotometric Determination of Daclatasvir Dihydrochloride by Ion-Pair Reaction with Bromophenol Blue, Bromothymol Blue and Bromocresol Green." Chemistry Research Journal 2, no. 6 (2017): 163–73. https://doi.org/10.5281/zenodo.13941717.

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Simple, rapid, cost-effective, sensitive spectrophotometric methods were developed for the determination of antivirus C drug (Daclatasvir dihydrochloride) in pure and dosage forms. The methods are based on the formation of ion-pair complexes between the drug and acid dyes (<em>i.e</em>., Bromothymol blue (BTB), bromocresol green (BCG) and bromophenol blue (BPB) solutions. The formed complexes were measured at 420, 416 and 415 nm for BCG, BPB and BTB methods, respectively, against a similarly prepared blank reagent. The analytical parameters and their effects on the reported systems were invest

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Manjunatha, D. H., S. M. T. Shaikh, K. Harikrishna, R. Sudhirkumar, Pradeep B. Kandagal, and J. Seetharamappa. "Simple and sensitive spectrophotometric methods for the determination of acebutolol hydrochloride in bulk sample and pharmaceutical preparations." Eclética Química Journal 33, no. 2 (2018): 37. http://dx.doi.org/10.26850/1678-4618eqj.v33.2.2008.p37-40.

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A direct, extraction-free spectrophotometric method has been developed for the determination of acebutolol hydrochloride (ABH) in pharmaceutical preparations. The method is based on ionpair complex formation between the drug and two acidic dyes (sulphonaphthalein) namely bromocresol green (BCG) and bromothymol blue (BTB). Conformity to Beer’s law enabled the assay of the drug in the range of 0.5-13.8 μg mL-1 with BCG and 1.8-15.9 μg mL-1 with BTB. Compared with a reference method, the results obtained were of equal accuracy and precision. In addition, these methods were also found to be specif

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Mariana, Horyn, Kucher Tetyana, Kryskiw Liubomyr, et al. "Development of the spectrophotometric method for the determination of metoprolol tartrate in tablets by using bromocresol green." ScienceRise: Pharmaceutical Science, no. 5 (39) (October 31, 2022): 55–63. https://doi.org/10.15587/2519-4852.2022.266068.

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<strong>The aim of the work</strong> was to develop and validate a spectrophotometric method for determining metoprolol tartrate in tablets based on the reaction with bromocresol green (BCG). <strong>Material and methods. </strong>Analytical equipment: two-beam UV-visible spectrophotometer Shimadzu model -UV 1800 (Japan), software UV-Probe 2.62, laboratory electronic balance RAD WAG AS 200/C, pH-meter И-160МИ. The following APIs, dosage forms, reagents and solvents were used in the work: pharmacopoeial standard sample (CRS) of metoprolol tartrate (Sigma-Aldrich, (≥ 98 %, HPLC)), B

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Altaee, Mohammed, Ahmed Mostafa Faheem, and Amal Ali Elkordy. "pH Gradient-Driven Loading of Doxorubicin into Niosomes: A Comparative Study Using Bromocresol Green as a Visual Indicator." Pharmaceutics 17, no. 7 (2025): 862. https://doi.org/10.3390/pharmaceutics17070862.

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Background: The active (remote) loading of drugs into nanoparticulate systems via the pH gradient technique has been proven highly successful in liposomes, as numerous formulations have reached the market. However, this is not the case for niosomes, as the full potential of this area remains largely undiscovered. The purpose of this research is to study the effect of different co-surfactants (Cremophor RH 40, Cremophor ELP and Solutol HS-15) on stabilising the niosomal membrane to enable the creation of a pH gradient. Methods: For visualisation of pH gradients, pH indicator bromocresol green (

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Awokoya, K. N., V. O. Oninla, O. A. Ogunkunle, et al. "Preparation of styrene-based imprinted polymer for the adsorption of hazardous bromocresol green dye: Equilibrium, kinetics and thermodynamics study." Ife Journal of Science 26, no. 1 (2024): 45–57. http://dx.doi.org/10.4314/ijs.v26i1.4.

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In this study, styrene was used as a functional monomer for the production of molecularly imprinted polymer (MIP) via free radical polymerization method, using bromocresol green dye (BCG) as template. A non-imprinted polymer (NIP), that excluded the template, was also synthesized. Both polymers were applied for the removal of BCG from aqueous medium. The synthesized polymers were characterized with Fourier transform infrared spectroscopy, scanning electron microscopy, and X-ray powder diffraction spectroscopic techniques. The effect of operating variables, such as pH, contact time, initial dye

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Horyn, Mariana, Tetyana Kucher, Liubomyr Kryskiw, et al. "Development of the spectrophotometric method for the determination of metoprolol tartrate in tablets by using bromocresol green." ScienceRise: Pharmaceutical Science, no. 5 (39) (October 31, 2022): 55–63. http://dx.doi.org/10.15587/2519-4852.2022.266068.

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The aim of the work was to develop and validate a spectrophotometric method for determining metoprolol tartrate in tablets based on the reaction with bromocresol green (BCG). Material and methods. Analytical equipment: two-beam UV-visible spectrophotometer Shimadzu model -UV 1800 (Japan), software UV-Probe 2.62, laboratory electronic balance RAD WAG AS 200/C, pH-meter И-160МИ. The following APIs, dosage forms, reagents and solvents were used in the work: pharmacopoeial standard sample (CRS) of metoprolol tartrate (Sigma-Aldrich, (≥ 98 %, HPLC)), BCG (Sigma-Aldrich, (≥ 98 %, HPLC)), "Metoprolol

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Aljubiri, Salha M., Walaa H. El-Shwiniy, Ayman A. O. Younes, Eid H. Alosaimi, and Badr Abd El-wahaab. "Use of Euphorbia balsamifera Extract in Precursor Fabrication of Silver Nanoparticles for Efficient Removal of Bromocresol Green and Bromophenol Blue Toxic Dyes." Molecules 28, no. 9 (2023): 3934. http://dx.doi.org/10.3390/molecules28093934.

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Silver nanoparticles (Ag-NPs) are attracting great attention for their use in various applications, along with methods for their green and facile production. In this study, we present a new eco-friendly approach based on the use of Euphorbia balsamifera extract (EBE) in the green synthesis of silver nanoparticles (Ag-NPs), which are then applied as a reducing and stabilizing agent for the efficient removal of water-based reactive dyes such as bromocresol green (BCG) and bromophenol blue (BPB). The as-prepared Ag-NPs are quasi-spherical in shape, with an average diameter of 20–34 nm. Diverse ch

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Harikrishna, K., Sudhir Kumar, J. Seetharamappa, and D. H. Manjunatha. "Sensitive extraction spectrophotometric methods for the determination of trazodone hydrochloride in pure and pharmaceutical formulations." Journal of the Serbian Chemical Society 71, no. 7 (2006): 829–37. http://dx.doi.org/10.2298/jsc0607829h.

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Two simple, rapid and sensitive extraction spectrophotometric methods have been developed for the assay of trazodone hydrochloride (TRH) in pure and pharmaceutical formulations. These methods are based on the formation of chloroform soluble ion-association complexes of TRH with bromocresol green (BCG) and with methyl orange (MO) in a KCl-HCl buffer of pH 1.5 (for BCG) and in a NaOAc-HCl buffer of pH 3.29 (for MO) with absorption maximum at 415 nm and at 422 nm for BCG and MO, respectively. The reaction conditions were optimized to obtain the maximum color intensity. The absorbance was found to

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Eticha, Tadele, Getu Kahsay, Teklebrhan Hailu, et al. "Development and Validation of an Extractive Spectrophotometric Method for Miconazole Nitrate Assay in Pharmaceutical Formulations." Journal of Analytical Methods in Chemistry 2018 (2018): 1–5. http://dx.doi.org/10.1155/2018/2191072.

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A simple extractive spectrophotometric technique has been developed and validated for the determination of miconazole nitrate in pure and pharmaceutical formulations. The method is based on the formation of a chloroform-soluble ion-pair complex between the drug and bromocresol green (BCG) dye in an acidic medium. The complex showed absorption maxima at 422 nm, and the system obeys Beer’s law in the concentration range of 1–30 µg/mL with molar absorptivity of 2.285 × 104 L/mol/cm. The composition of the complex was studied by Job’s method of continuous variation, and the results revealed that t

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Samanta, Subhodip. "Spectrophotometric Study of the Effect of Micellar Medium on the Dissociation Equilibrium of Sulfonephthalein pH Indicator Dye." Asian Journal of Chemistry 36, no. 7 (2024): 1592–600. http://dx.doi.org/10.14233/ajchem.2024.31673.

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The experimental determination of the mono-dianionic dissociation equilibrium constant (pKa2m) of sulfonephthalein pH-indicator dye bromocresol green (BCG) in cetyltrimethylammonium bromide (CTAB) micellar media revealed a deviation from its value in pure water (pKa2w). This discrepancy indicates that the presence of CTAB micellar media alters the dissociation behaviour of BCG compared to its behaviour in pure water. Such alterations suggest that the micellar environment influences the protonation and deprotonation processes of the dye molecule, likely through interactions between the dye and

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Zhang, Yi, Afsoun Abdollahi, Chaylen Andolino, et al. "Performance evaluation of different albumin assays for the detection of analbuminemia." PLOS ONE 19, no. 3 (2024): e0300130. http://dx.doi.org/10.1371/journal.pone.0300130.

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Analbuminemia is characterized by the near absence of albumin in the plasma. Different methods are available for measuring albumin levels, but they do not necessarily agree with one another. It is a concern that analbuminemic samples could be falsely characterized due to the incorrect estimation of albumin. The objective of the work was to evaluate the performance of different assays in detecting analbuminemia. Albumin knockout (Alb-/-) mouse plasma was used to test the suitability of different albumin assays for their ability to properly characterize extreme albumin deficiency. Bromocresol gr

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Sundar, Shrinidhi, Swetha Raghavendra Prasad, Dhivya Senthil Kumar, Sathya Selvarajan, Sowmya Krishnamurthy, and Sridharan Kopula Sathyamurthy. "Significance of serum protein electrophoresis in diagnosing multiple myeloma: A retrospective study at a tertiary care centre." Indonesian Journal of Medical Laboratory Science and Technology 7, no. 1 (2025): 40–48. https://doi.org/10.33086/ijmlst.v7i1.6712.

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Multiple myeloma (MM) is a hematologic malignancy characterized by uncontrolled plasma cell proliferation in the bone marrow, initially asymptomatic, often causing symptoms like bone pain, anemia, renal dysfunction, and increased infection susceptibility. The study investigates the clinical significance of inconsistencies in albumin measurement methods in multiple myeloma patients, focusing on serum protein electrophoresis (SPEP) and the bromocresol green (BCG) assay. A comparative analysis was conducted to evaluate the differences between albumin levels measured by SPEP and BCG, exploring how

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Nesalin, J. Adlin Jino, C. Jose Gnana Babu, G. Vijaya Kumar, and T. Tamizh Mani. "Validated Extractive Spectrophotometric Estimation of Tadalafil in Tablet Dosage Form." E-Journal of Chemistry 6, no. 3 (2009): 611–14. http://dx.doi.org/10.1155/2009/983146.

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Two simple spectrophotometric methods have been developed for the estimation of tadalafil in both pure and tablet dosage form. Methods A and B are based on the formation of ion-pair complexes of the drug with dyes such as bromothymol blue (BTB) and bromocresol green (BCG) in acidic buffer solution followed by their extraction with chloroform to form yellow colored chromogen with absorption maxima at 420 nm and 415 nm respectively. Beer’s law is valid in the concentration range of 10-50 mcg/mL for both the methods. These developed methods were validated for precision, accuracy, ruggedness and r

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M Aras, Neny Rasnyanti, Adinda Irwana, and Ameliana Utami. "FABRICATION OF CU MODIFIED NANO CHITOSAN WITH BROMOCRESOL GREEN AS INTELLIGENT PACKAGING." al Kimiya 11, no. 1 (2024): 12–28. http://dx.doi.org/10.15575/ak.v11i1.33742.

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In recent advancements, the development of smart packaging systems for food has focused on utilizing composite materials to enhance functionality and sustainability. In this study, the composite film from chitosan and PVA was combined at various concentrations (ranging from 0.1% to 0.5%) with the addition of Cu(500mM) and 1% STPP at a 5:1 ratio. An additional indicator was included to detect fish spoilage. The synthesized chitosan material was then blended with PVA to form a composite film. The film was characterized using FTIR, which confirmed the presence of fingerprint vibrations indicating

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Rajendraprasad, N., K. Basavaiah, and K. B. Vinay. "Sensitive Spectrophotometric Determination of Lamotrigine in Bulk Drug and Pharmaceutical Formulations using Bromocresol Green." Eclética Química Journal 35, no. 1 (2018): 55. http://dx.doi.org/10.26850/1678-4618eqj.v35.1.2010.p55-66.

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Two new, simple, rapid and reproducible spectrophotometric methods have been developed for the determination of lamotrigine (LMT) both in pure form and in its tablets. The first method (method A) is based on the formation of a colored ion-pair complex (1:1 drug/dye) of LMT with bromocresol green (BCG) at pH 5.02±0.01 and extraction of the complex into dichloromethane followed by the measurement of the yellow ion-pair complex at 410 nm. In the second (method B), the drug-dye ion-pair complex was dissolved in ethanolic potassium hydroxide and the resulting base form of the dye was measured at 62

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Abdulrahman, Sameer, and Kanakapura Basavaiah. "Spectrophotometric determination of dothiepin hydrochloride in pharmaceuticals through ion-pair complexation reaction." Chemical Industry and Chemical Engineering Quarterly 18, no. 2 (2012): 339–47. http://dx.doi.org/10.2298/ciceq111009010a.

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Two simple, sensitive and extraction-free spectrophotometric methods are described for the determination of dothiepin hydrochloride (DOTH) both in pure form and in pharmaceutical tablets. The methods are based on ion-pair complex formation between dothiepin base (DOT) and two acidic dyes, namely, bromophenol blue (BPB) or bromocresol green (BCG) with absorption maximum at 425 nm for BPB method or 430 nm for BCG method. Beer?s law is obeyed over the concentration ranges of 1.0-15.0 and 1.0-17.5 ?g mL-1 DOT for BPB and BCG methods, respectively. The molar absorptivity values and Sandell?s sensit

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Hou, Xuemei, Huijing Zhao, Ke-Qin Zhang, and Kai Meng. "Preparation of Wide-Domain pH Color-Changing Nanocapsules and Application in Hydrogel Fibers." Materials 15, no. 24 (2022): 8787. http://dx.doi.org/10.3390/ma15248787.

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In recent years, there has been an increase in demand for pH color-changing materials. These materials can visually communicate signals to people by connecting pH changes with color information. Embedding pH indicators into fibers to create flexible color-changing materials is an effective way to develop daily wearable products. For the stability of the indicator and the indirect contact of the indicator with the human body, it is usually necessary to encapsulate it in capsules. In this study, different pH indicators (Thymol Blue-TB, Bromocresol Green-BCG, and Bromocresol Purple-BCP) were mixe

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Setyaningrum, Lindawati, and Dhina Ayu Susanti. "PENETAPAN KADAR ALKALOID TOTAL PADA EKSTRAK N-HEKSAN DAN ETANOL BIJI KETUMBAR (Coriandrum sativum) MENGGUNAKAN SPEKTROFOTOMETER UV-Vis." Jurnal Riset Kefarmasian Indonesia 4, no. 3 (2022): 353–65. http://dx.doi.org/10.33759/jrki.v4i3.268.

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Coriander (Coriandrum sativum) is one of the medicinal plants which is known to contain secondary metabolites such as flavonoids, tannins, terpenoids, saponins, steroids, and alkaloids. Alkaloids have therapeutic effects as antimalarials and cancer. Research in determining the alkaloids in coriander was carried out by separating the alkaloids from other substances using the soxhlet method extraction with two solvents ethanol and n-hexane. The total alkaloid content is determined using a UV-VIS spectrophotometer at wavelength 351,5 nm. The reaction of alkaloids with Bromocresol green (BCG) is o

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Al Tamimi, Zainab, Longyan Chen, Xiaoxu Ji, Gary Vanderlaan, Matthew D. Gacura, and Davide Piovesan. "Preparation of Nanopaper for Colorimetric Food Spoilage Indication." Polymers 15, no. 14 (2023): 3098. http://dx.doi.org/10.3390/polym15143098.

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In this study, we are reporting the fabrication of a nanocellulose (NFC) paper-based food indicator for chicken breast spoilage detection by both visual color change observation and smartphone image analysis. The indicator consists of a nanocellulose paper (nanopaper) substrate and a pH-responsive dye, bromocresol green (BCG), that adsorbs on the nanopaper. The nanopaper is prepared through vacuum filtration and high-pressure compression. The nanopaper exhibits good optical transparency and strong mechanical strength. The color change from yellow to blue in the nanopaper indicator correspondin

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Shaban M., Khalil. "Spectrophotometric Determination of Trimebutine Through Ion- Pair and Charge- Transfer Complexation Reactions." Scientia Pharmaceutica 70, no. 4 (2002): 341–51. http://dx.doi.org/10.3797/scipharm.aut-02-33.

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Summary Two simple and sensitive spectrophotometric methods are described for the assay of trimebutine. The first method is based on the interaction of the basic drug in 1,2 dichloroethane with bromocresol green (BCG); bromophenol blue (BPB) and bromothymol blue (BTB) in the same solvent to produce a stable yellow ion-pair complexes , which absorbed at 410,406 and 405nm, respectively. The second method is based upon the interaction of the basic drug with iodine in 1,2 dichloroethane. The yellow colour formed due to the formation of charge-transfer complex showed two maxima absorbed at 292 and

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Amanlou, Massoud, Mohadeseh Zarei-Ghobadi, Mohammad Kazem Rofouei, Shahrooz Saremi, and Abbas Kebriaeezadeh. "Extractive Spectrophotometric Method for Determination of Pioglitazone Hydrochloride in Raw Material and Tablets Using Ion-Pair Formation." E-Journal of Chemistry 7, no. 3 (2010): 915–21. http://dx.doi.org/10.1155/2010/257593.

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A simple, rapid and extractive spectrophotometric method was developed for the determination of pioglitazone hydrochloride in pure and pharmaceutical formulations. This method is based on the formation of yellow ion-pair complex between the basic nitrogen of the drug and bromocresol green (BCG) in phthalate buffer of pH 2.4. The formed complexes were extracted with chloroform and measured at 419 nm. The analytical parameters and their effects on the proposed systems are investigated. Beer’s law was obeyed in the range 2.5-14 μg/mL with correlation coefficient ≥ 0.995. The proposed method has b

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Shirasaka, Yoshiyuki, Megumi Shichiri, Taku Kasai, et al. "A role of prostaglandin transporter in regulating PGE2 release from human bronchial epithelial BEAS-2B cells in response to LPS." Journal of Endocrinology 217, no. 3 (2013): 265–74. http://dx.doi.org/10.1530/joe-12-0339.

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Naturally occurring prostaglandin E2(PGE2) plays a role in inflammatory responses through eicosanoid signaling pathways. PGE2is impermeable to cell membranes at physiological pH and needs solute carrier across the membranes; however, it remains unclear how intercellular concentrations of PGE2are regulated under the condition of inflammation. We aimed to clarify a role of organic anion-transporting polypeptide 2A1 (OATP2A1/SLCO2A1), also known as prostaglandin transporter (PGT), in PGE2release from cells. Human bronchial epithelial BEAS-2B cells were treated with lipopolysaccharide (LPS), and P

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Susmitha, K., M. Thirumalachary, and G. Venkateshwarlu. "Spectrophotometric Determination of Bromhexine HCl in Pure and Pharmaceutical Forms." ISRN Analytical Chemistry 2013 (August 12, 2013): 1–7. http://dx.doi.org/10.1155/2013/861851.

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Five spectrophotometric methods for determination of bromhexine HCl have been developed, validated, and applied for the assay of the drug in pharmaceuticals. Methods A, B, and C are based on ion-pair complexation of drug, in acidic buffers, with triphenylmethane dyes, namely, bromothymol blue (BTB), bromophenol blue (BPB), and bromocresol green (BCG). The complexes are extracted into chloroform, and absorbance is measured at around 415 nm as function of concentration of the drug. The stoichiometry of the complex is found to be 1 : 1 in each case. Method D depends upon charge-transfer complexat

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Semenenko, S. I., K. P. Miedviedieva, S. O. Vasiuk, and B. S. Burlaka. "Development of a spectrophotometric technique for the quantitative determination of ademol." Current issues in pharmacy and medicine: science and practice 16, no. 1 (2023): 28–32. http://dx.doi.org/10.14739/2409-2932.2023.1.267437.

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According to statistics, craniocerebral injuries are often the cause of disability among the population. The choice of medicines for traumatic brain injuries is one of the most difficult problems in the complex treatment of such patients. Ademol (1-adamantylethyloxy-3-morpholino-2-propanol hydrochloride) is a promising medicinal substance that has a huge positive therapeutic effect of a protective act on the damaged brain and can be presented in medicinal preparations in different dosages. Therefore, the urgent task is the development of highly accurate, reliable, affordable, and fast methods

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Bienkovska, Tetyana, Ruslan Khoma, and Olena Vatral. "IMPREGNATED FIBROUS CHEMISORBENTS FOR THE COLORIMETRIC DETECTION OF AMMONIA." Ukrainian Chemistry Journal 88, no. 12 (2023): 175–88. http://dx.doi.org/10.33609/2708-129x.88.12.2022.175-188.

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The paper presents research results on the colorimetric behavior of impregnated fibrous chemisorbents (IFCS) of basic gases with visual identification of the dynamic absorption capacity “response” moment (IFCS-I) during the absorption of ammonia. Chemisorbents were obtained by impregnation of fibrous carriers with polybasic hydroxyl acid aqueous solutions with adding acid-base indicators (Ind). IFCS-I based on oxyethylenediphosphonic (IFCS-OEDPA-I), citric (IFCS-CA-I), and malic (IFCS-MA-I) acids were used. Azolithine (Az), lakmoid (LA), methyl orange (MO), methyl red (MR), Tropeolin OOO (TrOO

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Elbanna, Kh, R. M. El-Shahawy, and K. M. Atalla. " A new simple method for the enumeration of nitrifying bacteria in different environments." Plant, Soil and Environment 58, No. 1 (2012): 49–53. http://dx.doi.org/10.17221/412/2011-pse.

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In this work, a simple, safe and rapid method for enumerating nitrifying bacteria was used as an alternative to traditional harmful chemical methods. The enumeration of nitrifying bacteria was based upon the change of color of the growth media containing pH indicators in response to acid production during nitrification. The oxidation of ammonia to strong acids by nitrifiers leads to pH decrease, which can be detected by pH indicators such as methyl orange (MO), bromocresol green (BCG), methyl red (MR), bromothymol blue (BTB), and phenol red (PhR) using the Most Probable Number (MPN) technique.

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Y.M., Issa, Abou-Attia F.M., Abdel-Gawad F.M., and Abdel-Hamid S.M. "Spectrophotometric determination of some pharmaceutical piperazine derivatives by charge-transfer and ion-pair complexation methods." Scientia Pharmaceutica 70, no. 3 (2002): 253–69. http://dx.doi.org/10.3797/scipharm.aut-02-24.

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Simple and sensitive spectropliotometric methods are described for the assay of three piperazine derivatives ketoconazole, trimetazidine hydrochloride and piribedil based on cliarge-transfer and ion-pair complexation reactions. The first method is based on the reaction of the basic drug with iodine as o-acceptor in dry 1,2-dichloroethane to form a yellow colour due to the formation of charge-transfer complex showing maximum absorbence at 363, 364 and 359 nm for ketoconazole, trimetazidine hydrochlorid and piribedil, respectively. The second method is based on the reaction of basic drug with br

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