Journal articles: 'Bronchitas'

1

Gaparkhoeva, Z. M., O. A. Bashkina, and E. N. Seliverstova. "Comparative characteristics of bronchial obstruction formation trigger mechanisms in children with bronchial asthma and recurrent obstructive bronchitis." Kazan medical journal 97, no. 1 (February 15, 2016): 66–69. http://dx.doi.org/10.17750/kmj2016-66.

Full text

Abstract:

Aim. To study the comparative characteristics of the causative significant factors involved in the bronchial obstruction development in children with bronchial asthma and recurrent obstructive bronchitis.Methods. A cross-sectional (transversal) study of 50 children with bronchial asthma, 38 children with recurrent obstructive bronchitis was conducted. The differences and similarities of etiopathogenetic factors of the bronchial obstruction occurrence were revealed. According to medical history, in all patients regardless of the severity and duration of the disease at the time of examination, the impact of the factors, acting as triggers of bronchial asthma, according to patients, such as infectious agents, infectious allergens and aeroallergens, nighttime, climatic conditions deterioration, physical and/or emotional stress, was registered.Results. The main triggers that influence the bronchial obstruction occurrence in children with asthma were infectious factors impact, allergens and aeroallergens, and in patients with recurrent obstructive bronchitis more important in the bronchial obstruction development were infectious agents and weather conditions worsening (high humidity, fog, rain). However, unlike the other factors involved in the bronchial obstruction development in asthma, nighttime, allergens and aeroallergens did not have significant impact on the bronchial obstruction occurrence in children with recurrent obstructive bronchitis. In both groups, physical stress (jogging, gymnastics) and emotional stress (loud laugh, crying) contributed to the bronchial obstruction syndrome development with the corresponding clinical picture, but in the second group of children with recurrent obstructive bronchitis duration of cough lasted 2 times less (1-1,5 h) than in children with bronchial asthma (over 3 hours).Conclusion. Conducted comparative characteristics showed that there is a clear link with the trigger mechanisms of bronchial obstruction occurrence in bronchial asthma and recurrent obstructive bronchitis, and triggers, regardless of the severity and duration of disease, have the same effect on the recurrent obstructive bronchitis outcome.

APA, Harvard, Vancouver, ISO, and other styles

2

Šilinis, Darius, Juozas Sabalys, Edmundas Štarolis, Audrius Gradauskas, and Linas Andreika. "LAPAROSKOPINIŲ NEFREKTOMIJŲ, NEFRURETEREKTOMIJŲ IR INKSTO REZEKCIJŲ REZULTATŲ ANALIZĖ." Medicinos teorija ir praktika 20, no. 4 (October 24, 2014): 333–39. http://dx.doi.org/10.15591/mtp.2014.048.

Full text

Abstract:

Reikšminiai žodžiai: laparoskopija, inksto navikai, nefrektomija, rezekcija. Darbo tikslas. Straipsnio tikslas yra pateikti laparoskopinių nefrektomijų, nefrureterektomijų ir inksto rezekcijų rezultatus, atlikti jų analizę ir padaryti išvadas. Tyrimo medžiaga ir metodai. Nuo 2007 m. iki 2014 m. dėl įvairių priežasčių atlikta 66 laparoskopinės nefrektomijos, nefrureterektomijos ir inksto rezekcijos. Pagrindinės operacijų priežastys buvo inkstų ir šlapimtakių navikai, inkstų akmenligė, įvairios kilmės hidronefrozė, įgimti ir įgyti inkstų ir šlapimtakių sklaidos defektai, nefrosklerozė ir inkstų afunkcija. Nefrektomijų atlikta 50, nefureterektomijų – 9, inksto rezekcijų – 7, pastarosios buvo atliekamos dėl nedidelių (1–3 cm diametro) egzofitinių inkstų navikų ar terminalinės stadijos dvigubos kolektorikos inkstų viršutinio ar apatinio poliaus hidronefrotinės transformacijos ir afunkcijos. Rezultatai. Pacientų amžiaus vidurkis 55,8 m., nuo 19 m. iki 86 m. Dažniausios lydinčios ligos buvo arterinė hipertenzija, koronarinė širdies liga, cukrinis diabetas, struma, reumatoidinis artritas, opaligė, lėtinis bronchitas ir kt. Daugiausia atlikta nefrektomijų – 50, nefrureterektomijų – 9, inksto rezekcijų – 7. Konversijų į atviras operacijas atlikta 10 (15,2 proc.), daž- niausiai dėl kraujavimo ar techninių sunkumų, hemotransfuzijos prireikė 18 atvejų (27,3 proc.), kraujo netekimo vidurkis 500 ml. Operacijų vidurkis apie 188,48 ± 12,99 min., trumpiausia – 100 min., ilgiausia – 360 min. Stacionarizavimo laikas 14,95 ± 1,23 dienos, pooperacinių komplikacijų 12 atvejų (18,2 proc.). Nuskausminimui narkotinių analgetikų vidutiniškai sunaudota 4,55 ± 0,59 ampulės („Dolsin“, „Doloblok“), nenarkotinių – 5,01 ± 0,74 ampulės („Diklac“, „Dolmen“). Išvados. Nestiprūs pooperaciniai skausmai, mažas analgetikų vartojimas, nedideli pooperaciniai randai, geras kosmetinis efektas, nedidelis komplikacijų skaičius.

APA, Harvard, Vancouver, ISO, and other styles

3

Bodienkova, G. M., E. V. Boklazhenko, and O. V. Ushakova. "Immunoregulatory markers of bronchopulmonary diseases in workers of the aluminium industry." Occupational Health and Industrial Ecology, no. 9 (February 12, 2019): 29–34. http://dx.doi.org/10.31089/1026-9428-2018-9-29-34.

Full text

Abstract:

The laboratory immunologic study covered 106 male workers of aluminium industry, aimed to reveal features of changes in serum immunoglobulines and cytokines levels in accordance with occupational bronchopulmonary disease type: chronic nonobstructive bronchitis, chronic obstructive lung disease (COLD), bronchial asthma. General trend in the revealed changes in the patients with bronchopulmonary diseases is increased serum levels of Ig (IgA, IgM, IgG), anti-inﬂ ammatory cytokines (IL–1b, IL-8) and lower production (TNF-a, IL-4). Findings are multidirectional changes INF-g responsible for inﬂammatory response mobilization — that was increased vs. reference values in bronchial asthma patients, and in chronic nonobstructive bronchitis patients was lower than in reference group, and higher than in patients with COLD. The changes revealed were associated with disordered ratio IL-4/INF-g. Diﬀerences were observed for pleiotropic IL-2: it was hyperproduced in the workers with chronic nonobstructive bronchitis, but in the bronchial asthma and COLD patients it was decreased vs. the reference group and vs. the chronic nonobstructive bronchitis patients. The authors justified informative criteria of bronchial asthma diagnosis.

APA, Harvard, Vancouver, ISO, and other styles

4

Verhulst, Stijn, Lieve Boel, and Kim Van Hoorenbeeck. "Protracted bacterial bronchitis: bronchial aspirate versus bronchoalveolar lavage findings: a single-centre retrospective study." BMJ Paediatrics Open 3, no. 1 (June 2019): e000507. http://dx.doi.org/10.1136/bmjpo-2019-000507.

Full text

Abstract:

Retrospective chart review of 133 children who underwent bronchoscopy because of possible protracted bacterial bronchitis to compare the results of bronchial aspirates with those of bronchoalveolar lavage (BAL). When comparing BAL and bronchial aspirate in 70 patients where both samples were available, the result was comparable in 46 cases (65%). If only bronchial aspirates would have been available, seven patients (10%) would have been overtreated, four children (6%) undertreated and three (4%) would have received a different treatment. Although, BAL and bronchial aspirate are comparable in the majority of cases, differences exist with an impact on treatment decision, underlying the uncertainties in the pathophysiology of protracted bacterial bronchitis.

APA, Harvard, Vancouver, ISO, and other styles

5

Nesterenko, Zoia V. "Recurrent bronchitis as a clinical variant of functional changes of the respiratory system in children." Pediatrician (St. Petersburg) 8, no. 5 (December 15, 2017): 44–48. http://dx.doi.org/10.17816/ped8544-48.

Full text

Abstract:

Background. The high prevalence of acute respiratory infections in children, recurrent episodes of acute bronchitis remain to be one of the hot topics of pediatrics. The causes of recurrent exacerbations of bronchitis in children, despite the numerous research works on this issue, are not completely clear. Aim: to study the features of the clinic in children with recurrent bronchitis. Methods. There were 58 patients aged 3 to 12 years with recurrent bronchitis. A study demonstrated the close relationship between recurrent episodes of acute bronchitis not only with pre-preschool and preschool age (when bronchopulmonary tissue is not completely differentiated), with the influence of negative environmental factors, with bacterial, viral infection, but also with signs of connective tissue disorders (CTD) in them. Results. Revealing connective tissue insufficiency explains the causes of disorders of bronchial cartilage and connective tissue, that lead to the development of bronchial dyskinesia thus exacerbating the vulnerability of immature bronchopulmonary tissue along with autonomic dysfunction, typical for CTD. Involvement of several organs and systems in the CTD process changes the course of clinical symptoms of recurrent bronchitis. Probably by the main differentiation of tissues of organs at this age, including connective tissue, can be explained the fact that in 2/3 of the children observed by the age of 7 the manifestations of exacerbations of the disease ceased. In the half of the patients with recurrent episodes, who had bronchial obstruction in the first year of life, a allergy history, paroxysms of respiratory dyspnoea after an additional examination, – asthma was diagnosed; in one patient an aneurysm of the lung vessels was revealed. Conclusions. Basing on the conducted study, the use of the term “recurrent bronchitis” is advisable in children of the first seven years of life. In patients with continuing episodes of bronchitis bronchopulmonary pathology should be excluded; in patients with allergy history and symptoms of bronchial obstruction, spasmodic cough in previous episodes of bronchitis asthma should be excluded. The presence of symptoms of connective tissue disorders in children with recurrent bronchitis requires a careful examination of patients for the detection of comorbid diseases.

APA, Harvard, Vancouver, ISO, and other styles

6

Zhukova, Olga V. "The concept of risk factors in evaluation of «atypical» agents effecting formation of bronchial asthma in children with acute and recurrent obstructive bronchitis." Medical Journal of the Russian Federation 22, no. 2 (April 15, 2016): 77–81. http://dx.doi.org/10.18821/0869-2106-2016-22-2-77-81.

Full text

Abstract:

The study was carried out to establish relationship between occurrence of «atypical» infections in patients with acute obstructive and recurrent obstructive bronchitis and development of bronchial asthma based on concept of risks. Material and methods. As regards material for study the data of medical histories of patients hospitalized with acute obstructive and recurrent obstructive bronchitis and who were applied analysis for antibodies to «atypical» microflora (796 patients). The time-period of study made up four years from 2008 to 2011. During analyzed period immune enzyme analysis was implemented concerning antibodies to «atypical» microflora (Chlamydia pneumonia, Micoplasma pneumonia, Micoplasma hominis). The concept of risks’ identification was based on identification of ultimate risk in exposed and non-exposed groups, attributive risk, relative risk, population attributive risk. The standard errors and confidence interval for every type of risk were applied. Results. The methodical aspects of detection of relationship between occurrences of «atypical» infections in patients with acute and recurrent obstructive bronchitis and development of bronchial asthma were considered on the basis of concept of risks. The applied analysis demonstrated direct dependence of increasing of number of cases of development of bronchial asthma against the background of «atypical» infections. In the risk group the rate of occurrence makes up to 14,84%, in the control group - 1,67%, risk factor increases probability of development of bronchial asthma on 13,17%. The occurrence of “atypical” infection leads to increasing of cases of development of bronchial asthma up to 8.9 times. The index of potential harm made up to 7.59 i.e. if there are «atypical» infections in patients with acute and recurrent obstructive bronchitis every eighth exposed individual bronchial asthma is developed.

APA, Harvard, Vancouver, ISO, and other styles

7

Suadicani, Poul, Hans Ole Hein, and Finn Gyntelberg. "High Salt Intake and Risk of Chronic Bronchitis: The Copenhagen Male Study—A 10-Year Followup." ISRN Pulmonology 2011 (August 16, 2011): 1–6. http://dx.doi.org/10.5402/2011/257979.

Full text

Abstract:

Objective. The role of salt intake as a risk factor for asthma, bronchial hyperresponsiveness, and other bronchial symptoms has been addressed in a number of studies. Collectively, these studies indicate an increased risk of bronchial symptoms with high consumption of salt, but the issue remains controversial. We tested prospectively the hypothesis that salt intake would be an independent risk factor for chronic bronchitis (CB). Design. A 10-year prospective study of 2,183 men aged 46 to 65 years without any relevant lung symptoms at baseline. Main Outcome. Chronic bronchitis. Results. During the 10-year followup, the overall incidence of CB was 7.1% among men without any relevant lung symptoms at baseline. In a multiple logistic regression analysis, controlling for age, smoking habits, occupational dust exposure, alcohol use, and social class, the odds ratio associated with self-assessed high salt preference (reported by 24%) was 1.6 (1.1–2.4). Interpretation. The results suggest that salt restriction may prevent chronic bronchitis.

APA, Harvard, Vancouver, ISO, and other styles

8

Raoufi, Mohammed, Leila Achachi, Fatima Zahra Mrabet, Laila Herrak, Mustapha El Ftouh, Najoua Bourhroum, and Nezha Ouazzani Taibi. "A Rare Case of Idiopathic Plastic Bronchitis." Case Reports in Pulmonology 2017 (2017): 1–3. http://dx.doi.org/10.1155/2017/4789751.

Full text

Abstract:

Plastic bronchitis is a rare disorder characterized by formation of large, branching bronchial casts, which are often expectorated. We present an interesting case of a 35-year-old woman who presented for evaluation of a chronic cough productive of voluminous secretions. Clinical and radiological examination confirmed a total left lung atelectasis without any pathological mediastinal node. Flexible bronchoscopy demonstrated tenacious, thick, and sticky whitish secretions blocking the left stem bronchus. This material was extracted, and inspection demonstrated a bronchial cast, whose pathological analysis revealed necrotic epithelial cells, some eosinophils, and Charcot-Leyden crystals. Two days after bronchoscopy, the patient rejected more bronchial casts, and dyspnea improved. Control of chest x-ray revealed complete left lung aeration and the diagnosis of idiopathic plastic bronchitis was obtained. This article shows the interest in clinical practice to evoke the diagnosis of plastic bronchitis in front of a productive chronic cough. Our case illustrates a rare clinical presentation represented by an atelectasis of an entire lung.

APA, Harvard, Vancouver, ISO, and other styles

9

Gaysaev, M., and E. Gancgorn. "CLINICAL CASE: CHRONIC BRONCHITIS AS A RISK FACTOR FOR UNCONTROLLED BRONCHIAL ASTHMA." Clinical Medicine and Pharmacology 6, no. 1 (June 18, 2020): 43–47. http://dx.doi.org/10.12737/2409-3750-2020-6-1-43-47.

Full text

Abstract:

M.O. GAISAEV, E.V. GANTSGORN A clinical case of a 55-year-old patient with persistent moderate uncontrolled bronchial asthma and acute stage of chronic bronchitis is described. In the aspect of etiopathogenetic features and modern approaches to the treatment of this pathology, the tactics of the pharmacotherapy performed are analyzed on the example of this patient. The presented clinical case demonstrates the feasibility of a differentiated approach to the treatment of patients with chronic bronchitis as one of the important risk factors for the progression of bronchial asthma.

APA, Harvard, Vancouver, ISO, and other styles

10

Koloskova, O. K., L. A. Ivanova, T. M. Bilous, and L. V. Mykaliuk. "ON THE OPTIMIZATION OF VERIFICATION OF BRONCHIAL ASTHMA IN CHILDREN WITH MANIFESTATIONS OF BRONCHOOBSTRUCTIVE SYNDROME." Likarska sprava, no. 7-8 (December 30, 2018): 55–60. http://dx.doi.org/10.31640/jvd.7-8.2018(9).

Full text

Abstract:

Bronchial asthma in children has different causes of development, and examination of markers to verify the disease in case of the first signs of bronchial obstruction is an important issue to find transitory or persisting asthma phenotypes. There were examined 156 children with signs of bronchial obstruction syndrome.They were divided into three clinical groups: the first (І) group included 36 children with acute obstructive bronchitis (average age 6,1 ± 0,6 years, 36 % of girls), the second (ІІ) group – 74 children with relapsing obstructive bronchitis (average age 5,60 ± 0,34 years, 38 % of girls), the third (ІІІ) group included 46 children suffering from bronchial asthma for two years (average age 11,6 ± 0,5 years, 33 % of girls).The family history of one of the parents and of both parents, aggravated by allergic diseases, was most often found in patients with bronchial asthma: in 34,8 % of children on maternal side (Р ˂ 0,05 with І, ІІ : ІІІ), in 17,4 % of cases on paternal side (Р ˃ 0,05) and in 4,3 % – on both sides (Р ˃ 0,05). Patients suffering from bronchial asthma in 78,3 % of cases demonstrated domestic, food or medical allergy, that was reliably higher than that of an appropriate number of children in І (33,3 %) and ІІ groups (37,2 %), Р ˂ 0,05. In case of complicated family anamnesis with allergic diseases and the level of nitrogen monoxide metabolites more than 40 µmol/l the diagnostic value of this test in detection of bronchial asthma is the following: sensitivity 87,5 %, specificity 89,5 %, predicted value of a negative result 97,1 % with realization odds ratio 59,5, relative risk 22,3. Relative blood eosinophilia (Р ˂ 0,05 with ІІІ : І, ІІ) and sputum eosinophilia (Р ˂ 0,05 with ІІІ : І, ІІ) in children suffering from bronchial asthma as compared to the patients with obstructive bronchitis were found. In patients with verified asthma compared with children with acute and recurrent obstructive bronchitis, a significantly higher number of eosinophils, alveolar macrophages and epithelial cells in sputum is observed, which is accompanied by a lower content of neutrophil granulocytes and lymphocytes.Thus, in children with bronchial obstruction, even at its first episode, to identify the risk of bronchial asthma, a family history should be carefully collected on the burden of allergic diseases, the history of the child on allergic manifestations, in the dynamics to determine the number of eosinophils in the peripheral blood and induced sputum, the level serum immunoglobulin E and the content of metabolites of nitric oxide in the condensate of exhaled air.

APA, Harvard, Vancouver, ISO, and other styles

11

Koloskova, O. K., L. A. Ivanova, T. M. Bilous, and L. V. Mykaliuk. "ON THE OPTIMIZATION OF VERIFICATION OF BRONCHIAL ASTHMA IN CHILDREN WITH MANIFESTATIONS OF BRONCHOOBSTRUCTIVE SYNDROME." Likarska sprava, no. 7-8 (December 30, 2018): 55–60. http://dx.doi.org/10.31640/vd.7-8.2018(9).

Full text

Abstract:

Bronchial asthma in children has different causes of development, and examination of markers to verify the disease in case of the first signs of bronchial obstruction is an important issue to find transitory or persisting asthma phenotypes. There were examined 156 children with signs of bronchial obstruction syndrome.They were divided into three clinical groups: the first (І) group included 36 children with acute obstructive bronchitis (average age 6,1 ± 0,6 years, 36 % of girls), the second (ІІ) group – 74 children with relapsing obstructive bronchitis (average age 5,60 ± 0,34 years, 38 % of girls), the third (ІІІ) group included 46 children suffering from bronchial asthma for two years (average age 11,6 ± 0,5 years, 33 % of girls).The family history of one of the parents and of both parents, aggravated by allergic diseases, was most often found in patients with bronchial asthma: in 34,8 % of children on maternal side (Р ˂ 0,05 with І, ІІ : ІІІ), in 17,4 % of cases on paternal side (Р ˃ 0,05) and in 4,3 % – on both sides (Р ˃ 0,05). Patients suffering from bronchial asthma in 78,3 % of cases demonstrated domestic, food or medical allergy, that was reliably higher than that of an appropriate number of children in І (33,3 %) and ІІ groups (37,2 %), Р ˂ 0,05. In case of complicated family anamnesis with allergic diseases and the level of nitrogen monoxide metabolites more than 40 µmol/l the diagnostic value of this test in detection of bronchial asthma is the following: sensitivity 87,5 %, specificity 89,5 %, predicted value of a negative result 97,1 % with realization odds ratio 59,5, relative risk 22,3. Relative blood eosinophilia (Р ˂ 0,05 with ІІІ : І, ІІ) and sputum eosinophilia (Р ˂ 0,05 with ІІІ : І, ІІ) in children suffering from bronchial asthma as compared to the patients with obstructive bronchitis were found. In patients with verified asthma compared with children with acute and recurrent obstructive bronchitis, a significantly higher number of eosinophils, alveolar macrophages and epithelial cells in sputum is observed, which is accompanied by a lower content of neutrophil granulocytes and lymphocytes.Thus, in children with bronchial obstruction, even at its first episode, to identify the risk of bronchial asthma, a family history should be carefully collected on the burden of allergic diseases, the history of the child on allergic manifestations, in the dynamics to determine the number of eosinophils in the peripheral blood and induced sputum, the level serum immunoglobulin E and the content of metabolites of nitric oxide in the condensate of exhaled air.

APA, Harvard, Vancouver, ISO, and other styles

12

Smirnova-Saprytskaya, M. Yu, G. L. Osipova, T. P. Ospelnikova, G. A. Danilina, and K. A. Zykov. "Microbiological features of bronchial asthma and chronic obstructive pulmonary disease during remission." Journal of Clinical Practice 9, no. 4 (December 15, 2018): 40–46. http://dx.doi.org/10.17816/clinpract9440-46.

Full text

Abstract:

Background: Bronchial asthma and chronic obstructive pulmonary disease are currently the fifth leading cause of death in the world. The combination of bronchial asthma and chronic obstructive pulmonary disease seems to be a unique disease resulting from the interaction of genetic, pathological and functional factors. Aim: Study of clinical and functional parameters, bacterial spectrum in patients with combination of asthma and chronic obstructive pulmonary diseases bronchitis and non-bronchitis types. Methods: Clinical and functional examination of 69 patients with obstructive respiratory diseases, of which 49 patients with asthma combined with chronic obstructive pulmonary disease of bronchitis and non-bronchitis types. The microbiological spectrum of nasal pharynx induced by sputum was studied. Results: The following microorganisms were isolated: Staphylococcus (S. aureus, S. epidermidis), Neisseria subflava, Streptococcus (α-haemolyticus, β-haemolyticus), Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Branhamella catarrhalis, Enterococcus, Haemophilus influenzae, Candida albicans, Aspergillus spp., Actinomyces spp., Cladosporium, Penicillium, and others. Conclusion: A more pronounced quantitative content and a more diverse microbial landscape leads to a more severe course of the disease asthma combined withchronic obstructive pulmonary disease especially of the bronchitis type.

APA, Harvard, Vancouver, ISO, and other styles

13

Cartin-Ceba, Rodrigo, Marie Christine Aubry, and Kaiser Lim. "Dyspnea and Wheezing after Adenosine Injection in a Patient with Eosinophilic Bronchitis." Case Reports in Medicine 2009 (2009): 1–4. http://dx.doi.org/10.1155/2009/356462.

Full text

Abstract:

A 58-year-old nonsmoker female was referred for evaluation of chronic cough of 13 months duration. After an initial work-up, the patient was diagnosed to have chronic cough due to eosinophilic bronchitis. The diagnostic work-up for eosinophilic bronchitis and bronchial biopsy is discussed. Eosinophilic bronchitis is differentiated from asthma. In addition, the patient developed dyspnea, flushing, and wheezing after the administration of adenosine during a cardiac stress test in spite of a negative methacholine challenge. This indirect stimulus of airway hyperresponsiveness suggests the possible involvement of mast cells in eosinophilic bronchitis.

APA, Harvard, Vancouver, ISO, and other styles

14

Ivanova, L. A., M. N. Gorizontova, Yu V. Statsenko, I. V. Babenko, G. M. Vologzhanina, and O. V. Krupenina. "Complex laboratory investigations in occupational respiratory diseases." PULMONOLOGIYA, no. 4 (August 28, 2008): 26–30. http://dx.doi.org/10.18093/0869-0189-2008-0-4-26-30.

Full text

Abstract:

Results of complex laboratory examination of 103 patients with dust related bronchitis caused by exposure of various industrial dusts, 22 patients with pneumoconiosis and 12 subjects not having respiratory pathology and not exposed to quartz dust or any other occupational hazards are presented in this article. Laboratory examination included morphological investigations of sputum and bronchial brush biopsy specimens, cytochemical characterization of bronchial ciliated epithelium and blood cells, and bacteriological and serological investigations of bronchial mucus. Our results demonstrated that morphological lesions of bronchial epithelium cells leading to their death followed cell dysfunction, disorders of enzyme activity, hypoxemia, predominance of Haemophilus influenzae in microflora, and significant inflammatory and allergic response in blood. These changes were found in different clinical stages of dust related bronchitis and pneumoconiosis. The findings obtained are of great importance for understanding pathogenic mechanisms of dust related lung diseases as well as from clinical point of view such as diagnosis and development of individual treatment strategies.

APA, Harvard, Vancouver, ISO, and other styles

15

Habib, Sheila A., Robert C. Vasko, Jack Badawy, and Gregory M. Anstead. "Plastic Bronchitis in an AIDS Patient with Pulmonary Kaposi Sarcoma." Case Reports in Pulmonology 2018 (September 27, 2018): 1–5. http://dx.doi.org/10.1155/2018/9736516.

Full text

Abstract:

Plastic bronchitis is the expectoration of bronchial casts in the mold of the tracheobronchial tree. It is a rare occurrence of unknown etiology that has been primarily described in children with congenital heart disease. In this case report, we present the first reported case of plastic bronchitis in a patient with pulmonary Kaposi sarcoma and underlying HIV infection.

APA, Harvard, Vancouver, ISO, and other styles

16

Costabel, Ulrich. "Bronchial Eosinophilia in Exacerbation of Bronchitis." American Journal of Respiratory and Critical Care Medicine 164, no. 1 (July 2001): 3–4. http://dx.doi.org/10.1164/ajrccm.164.1.2104021c.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Demont, Patricia, Tobias Fehr, Thomas Geiser, and Sebastian R. Ott. "Bronchial Cast Formation in Plastic Bronchitis." Respiration 91, no. 4 (2016): 325–26. http://dx.doi.org/10.1159/000445441.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Yakubova, Z. N. "Corrigibility of respiratory mechanics in patients with pre-asthma and bronchial asthma." Kazan medical journal 67, no. 1 (January 15, 1986): 19–21. http://dx.doi.org/10.17816/kazmj62899.

Full text

Abstract:

Respiratory mechanics on a pneumotachograph was studied in 30 patients with preasthma, proceeding against a background of chronic bronchitis, and in 35 patients with bronchial asthma of medium severity (according to classification of A.D. Ado and P.K. Bulatov, 1969). Complex therapy included anti-inflammatory, desensitizing drugs and agents improving bronchial drainage function - bronchodilators.

APA, Harvard, Vancouver, ISO, and other styles

19

El Hefny, Anissa, Amal El Beshlawy, Samia Nour, and Mohamed Said. "Ketotifen in the Treatment of Infants and Young Children with Wheezy Bronchitis and Bronchial Asthma." Journal of International Medical Research 14, no. 5 (September 1986): 267–73. http://dx.doi.org/10.1177/030006058601400507.

Full text

Abstract:

Ketotifen, an orally-administered anti-anaphylactic and antihistamine compound, was given in a dose of 0.06 mg/kg to 142 infants and young children presenting either with non-infected wheezy bronchitis or bronchial asthma to an allergy out-patient department. Treatment continued for 12 weeks. At the end of this time, ketotifen was considered to be very effective or effective in 70% of the children. The effect was more marked in non-infected wheezy bronchitis (83.55% response) than in bronchial asthma (56.5% response), perhaps because factors such as leukotrienes, prostaglandins and thromboxanes tend to produce a sustained bronchoconstriction in the latter condition. Ketotifen was not associated with any adverse effects and did not cause behavioural problems. Patients found it palatable and acceptable. The main disadvantage was that symptoms recurred within days of stopping treatment. Especially in non-infected wheezy bronchitis, ketotifen should be given for a year or longer to older children (older than 30 months) who have shown an initial good response to the drug.

APA, Harvard, Vancouver, ISO, and other styles

20

Mizernitskiy, Yu L., I. M. Melnikova, V. A. Pavlenko, V. N. Volovenko, and N. M. Kondrashova. "Clinical efficacy of the affinity purified antibodies to the protein S100 in the complex rehabilitation of the infants with acute obstructive bronchitis affected by perinatal pathology of central nervous system." Pacific Medical Journal, no. 4 (December 28, 2019): 42–46. http://dx.doi.org/10.34215/1609-1175-2019-4-42-46.

Full text

Abstract:

Objective: The objective is to assess the clinical efficacy of the inclusion of release-active medication of affinity purified antibodies to protein S100 in complex rehabilitation of infants with old acute obstructive bronchitis affected by perinatal pathology of central nervous system of hypoxic genesis.Methods: 210 infants aged from 2–36 months, who suffered events of acute obstructive bronchitis, were examined. Along with clinical methods of examination, a computer bronchophonography and assessment of heart rate variability were performed.Results: Additional inclusion of release-active medication ‘Tenoten for children’ in the complex of rehabilitation of these patients had a positive effect on autonomic balance and autonomic component of bronchial obstruction. At the same time, the short course of Tenoten (1 month) did not prevent recurrent events of bronchial obstruction.Conclusions: Probably, patients with recurrent events of acute bronchial obstruction in combination with pronounced functional disorders of vegetative state require longer courses of release-active medication which normalized the activity of the central nervous system.

APA, Harvard, Vancouver, ISO, and other styles

21

Stober, Vandy P., Christopher Szczesniak, Quiana Childress, Rebecca L. Heise, Carl Bortner, John W. Hollingsworth, Isabel P. Neuringer, Scott M. Palmer, and Stavros Garantziotis. "Bronchial epithelial injury in the context of alloimmunity promotes lymphocytic bronchiolitis through hyaluronan expression." American Journal of Physiology-Lung Cellular and Molecular Physiology 306, no. 11 (June 1, 2014): L1045—L1055. http://dx.doi.org/10.1152/ajplung.00353.2013.

Full text

Abstract:

Epithelial injury is often detected in lung allografts, however, its relation to rejection pathogenesis is unknown. We hypothesized that sterile epithelial injury can lead to alloimmune activation in the lung. We performed adoptive transfer of mismatched splenocytes into recombinant activating gene 1 (Rag1)-deficient mice to induce an alloimmune status and then exposed these mice to naphthalene to induce sterile epithelial injury. We evaluated lungs for presence of alloimmune lung injury, endoplasmic reticulum (ER) stress, and hyaluronan expression, examined the effect of ER stress induction on hyaluronan expression and lymphocyte trapping by bronchial epithelia in vitro, and examined airways from patients with bronchiolitis obliterans syndrome and normal controls histologically. We found that Rag1-deficient mice that received mismatched splenocytes and naphthalene injection displayed bronchial epithelial ER stress, peribronchial hyaluronan expression, and lymphocytic bronchitis. Bronchial epithelial ER stress led to the expression of lymphocyte-trapping hyaluronan cables in vitro. Blockade of hyaluronan binding ameliorated naphthalene-induced lymphocytic bronchitis. ER stress was present histologically in >40% of bronchial epithelia of BOS patients and associated with subepithelial hyaluronan deposition. We conclude that sterile bronchial epithelial injury in the context of alloimmunity can lead to sustained ER stress and promote allograft rejection through hyaluronan expression.

APA, Harvard, Vancouver, ISO, and other styles

22

Vizel, А. A., R. F. Khamitov, E. D. Gizatullina, S. M. Khasanova, R. S. Fatkullina, M. S. Filatova, Y. A. Aznabaeva, and I. N. Khalfiev. "Efficiency of ambrosan in bronchopulmonary diseases." Kazan medical journal 80, no. 3 (April 2, 1999): 179–83. http://dx.doi.org/10.17816/kazmj66684.

Full text

Abstract:

As many as 137 patients with acute and chronic bronchitis, pneumonia, bronchial asthma, bron- choectatic disease and tuberculosis were given ambrosan in a dose of 30 mg three times per day in combined therapy (all patients were given antibacterial drugs). It was shown that ambrosan softens cough, promotes sputum passage, positively affects rhe bronchopulmonary disease course. This effect was the most pronounced in acute and chronic bronchitis (87% and 94,8%).

APA, Harvard, Vancouver, ISO, and other styles

23

Prikhodko, A. G., and A. V. Kolosov. "The particularities of cold-induced bronchial hyperreactivity in patients with chronic respiratory diseases." PULMONOLOGIYA, no. 1 (February 28, 2008): 69–74. http://dx.doi.org/10.18093/0869-0189-2008-0-1-69-74.

Full text

Abstract:

Prevalence and clinical and physiological features of coldinduced bronchial hyperreactivity in patients with respiratory diseases were shown. In patients with chronic bronchitis, coldinduced bronchial hyperreactivity was associated with worsening of lung ability to condition the inspired air. Disorders of respiratory heat exchange in patients with bronchial asthma were not the leading cause of coldinduced bronchoconstriction, which was associated with high sensitivity of airway receptors and IgEdependent mechanisms. A set of diagnostic criteria allowing detection of the dominant mechanism of airway cold hyperreactivity was proposed.

APA, Harvard, Vancouver, ISO, and other styles

24

Ado, A. D., and R. M. Zolotareva. "Cholinergic variant of infectious allergic bronchial asthma." Kazan medical journal 67, no. 5 (September 15, 1986): 352–54. http://dx.doi.org/10.17816/kazmj70699.

Full text

Abstract:

Infectious and allergic bronchial asthma occurs on the basis of inflammatory diseases: acute and chronic pneumonia, influenza, bronchitis, pathology of ENT organs. Bacteria, toxins, decay products of own tissues cause sensitization process and subsequent allergic reaction, which is localized in the tissues of the bronchial tree, involves primarily the peripheral structures of the autonomic nervous system and can cause increased excitability of the parasympathetic department.

APA, Harvard, Vancouver, ISO, and other styles

25

Maksimov, N. I. "Application of laser acupuncture in patients with bronchial asthma and chronic obstructive bronchitis." Kazan medical journal 67, no. 1 (January 15, 1986): 44–45. http://dx.doi.org/10.17816/kazmj63061.

Full text

Abstract:

Effectiveness of laser acupuncture in 152 patients with different stages and forms of bronchial asthma and in 58 patients with chronic obstructive bronchitis in outpatient settings (76 men, 134 women) was studied.

APA, Harvard, Vancouver, ISO, and other styles

26

Maltsev, S. V., L. R. Smirnova, and N. I. Kuznetsova. "Influence of sensitization on the character of immunological disorders in bronchial asthma and asthmatic bronchitis in children." Kazan medical journal 67, no. 4 (July 15, 1986): 303. http://dx.doi.org/10.17816/kazmj70559.

Full text

Abstract:

The aim of the work was to study the state of immunological reactivity in bronchial asthma and asthmatic bronchitis in children depending on the severity of the process and the degree of sensitization to bacterial allergens.

APA, Harvard, Vancouver, ISO, and other styles

27

DAVIES, Julia R., Hans W. HOVENBERG, Carl-Johan LINDÉN, Richard HOWARD, Paul S. RICHARDSON, John K. SHEEHAN, and Ingemar CARLSTEDT. "Mucins in airway secretions from healthy and chronic bronchitic subjects." Biochemical Journal 313, no. 2 (January 15, 1996): 431–39. http://dx.doi.org/10.1042/bj3130431.

Full text

Abstract:

Little is known about whether the properties of respiratory mucins are altered as a result of airway irritation, but histochemical studies of respiratory tract secretory cells show a more ‘acidic’ staining pattern after exposure to tobacco smoke. Furthermore it has been suggested that proteoglycans are the major glycoconjugates in ‘normal’ respiratory secretions, whereas mucins predominate in sputum. To investigate these observations further, mucins from secretions collected from the tracheal surface of healthy non-smoking ‘normal’ subjects and sputum from patients with chronic bronchitis were compared. All samples contained one major mucin population after density-gradient centrifugation, and a small amount of ‘denser’ mucin was present in some chronic bronchitic and one of the ‘normal’ samples. Proteoglycans were not a major component of ‘normal’ secretions. The major mucin population from chronic bronchitic samples had molecular masses between 10 and 30 MDa and behaved as random coils in solution. Whole mucins from ‘normal’ individuals and chronic bronchitic patients were excluded from Sepharose CL-2B, whereas reduced subunits were included. Proteolysis of subunits yielded two populations of high-molecular-mass glycopeptides differing in size, suggesting the presence of two different tandem repeat regions in the mucins. Finally, mucins from patients with chronic bronchitis are less, rather than more, acidic than those from ‘normal’ individuals. Mucins from bronchitic sputum and ‘normal’ secretions are thus similar in their macromolecular properties, but differ slightly in charge density.

APA, Harvard, Vancouver, ISO, and other styles

28

Cox, Conor, Melanie Kjarsgaard, Michael G. Surette, P. Gerard Cox, and Parameswaran Nair. "A Multidimensional Approach to the Management of Severe Asthma: Inflammometry, Molecular Microbiology and Bronchial Thermoplasty." Canadian Respiratory Journal 22, no. 4 (2015): 221–24. http://dx.doi.org/10.1155/2015/459187.

Full text

Abstract:

The authors illustrate the merits of identifying the components of diseases (eg, bronchitis and airway hyper-responsiveness) that contribute to exacerbations in the management of a patient with severe asthma. Quantitative cell counts in sputum identified a neutrophilic – as opposed to eosinophilic – bronchitis that enabled a stepwise weaning of prednisone. Molecular microbiology and extended culture methods identified anaerobes and other airway microbiome that helped to guide the use of antibiotics. Further control of asthma was achieved by performing bronchial thermoplasty.

APA, Harvard, Vancouver, ISO, and other styles

29

Abaturov, Alexandr E., and Olena O. Rusakova. "Immunogenetic predictors of the development of bronchial obstruction during acute bronchitis in infants." Wiadomości Lekarskie 73, no. 2 (2020): 316–20. http://dx.doi.org/10.36740/wlek202002121.

Full text

Abstract:

The aim: To determine the most informative immunological and molecular genetic factors which reflect the characteristics of the inflammatory process and make it possible to predict the development of bronchial obstruction during acute bronchitis in infants. Materials and methods: 120 children aged from 6 months to 3 years old with acute bronchitis were examined. We determined NF-κB expression level in peripheral blood lymphocytes by flow cytometry method, the serum concentrations of interferon-γ, interleukins 4, 12 and 13 by ELISA, total IgE serum level by ECLIA and calculated the relative risk (RR) for each of these parameters. Results: The risk of bronchial obstruction development was high when the relative number of lymphocytes expressing NF-κB was under 49.8% (RR=3.27, 95% CI=2.09-4.92). IL-12 serum concentration from 41.35 pg/ml to 173.06 pg/ml (RR=5.35, 95% CI=2.82-9.15) and IL-13 serum concentration from 4.06 pg/ml to 6.71 pg/ml (RR=4.0, 95% CI=2.39-6.41) were early predictors of the appearance of wheezing during the disease. The probability of the development of bronchial obstruction was low when the relative number of lymphocytes expressing NF-κB was above 49.8% (RR=0.40, 95% CI=0.28-0.62). NF-κB expression level above 0.91 Units (RR=0.20, 95% CI=0.11-0.39), serum concentrations of IFN-γ above 9.83 pg/ml (RR=0.50, 95% CI=0.31-0.81), IL-12 above 173.06 pg/ml (RR=0.49, 95% CI=0.30-0.82), IL-13 above 6.71 pg/ml (RR=0.40, 95% CI=0.22-0.72) reduced the probability of the appearance of wheezing significantly. Conclusions: The development of bronchial obstruction during acute bronchitis in infants is associated with the relatively low NF-κB and IL-12 levels, imbalance in IFN-γ and IL-13 production.

APA, Harvard, Vancouver, ISO, and other styles

30

Peyton, Christine. "Protein-Losing Enteropathy and Plastic Bronchitis After the Fontan Operation." Critical Care Nurse 38, no. 6 (December 1, 2018): e5-e12. http://dx.doi.org/10.4037/ccn2018784.

Full text

Abstract:

Protein-losing enteropathy and plastic bronchitis remain challenging to treat despite recent treatment advances. Protein-losing enteropathy and plastic bronchitis have been diagnosed in patients with cardiomyopathy, constrictive pericarditis, and congestive heart failure. This article focuses on patients with protein-losing enteropathy or plastic bronchitis following the Fontan procedure. Patients with single-ventricle physiology who have undergone the Fontan procedure are at risk for these conditions. Fontan physiology predisposes patients to chronically low cardiac output, increased central venous pressure, and congestive heart failure. These altered hemodynamics lead to increased mesenteric vascular resistance, resulting in venous hypertension and congestion in protein-losing enteropathy. Plastic bronchitis is a complex disease in which chronic high lymphatic pressures from Fontan physiology cause acellular bronchial casts to develop. These entities may also occur in patients with normal Fontan hemodynamics. This article also covers medical and surgical interventions for protein-losing enteropathy and plastic bronchitis. (Critical Care Nurse. 2018;38[6]:e5–e12)

APA, Harvard, Vancouver, ISO, and other styles

31

Nakamura, Y., L. Tate, R. F. Ertl, M. Kawamoto, T. Mio, Y. Adachi, D. J. Romberger, et al. "Bronchial epithelial cells regulate fibroblast proliferation." American Journal of Physiology-Lung Cellular and Molecular Physiology 269, no. 3 (September 1, 1995): L377—L387. http://dx.doi.org/10.1152/ajplung.1995.269.3.l377.

Full text

Abstract:

Chronic bronchitis frequently leads to irreversible airway obstruction. Alteration of airway architecture with abnormal airway connective tissue is thought to play an important role in this process. We hypothesized that the epithelial cells that line the airways modulate the development of peribronchial fibrosis and fixed airway obstruction by directing fibroblast proliferation. To assess this, we examined stimulatory activities for human lung fibroblast proliferation in bovine bronchial epithelial cell-conditioned medium. The conditioned medium stimulated the proliferation of fibroblasts in a serum-free culture system in a concentration-dependent manner. The fibroblast growth stimulatory activity was heterogenous, with molecular masses of > 50 and approximately 10 kDa. Bronchial epithelial cell-conditioned medium also contained fibroblast growth inhibitory factors, including both transforming growth factor (TGF)-beta and, based on indomethacin sensitivity, cyclooxygenase products. TGF-beta appeared to contribute to the morphological change of fibroblasts induced by the conditioned medium. Co-culture of human lung fibroblasts with bronchial epithelial cells resulted in a stimulation of fibroblast proliferation. In summary, airway epithelial cells appear to regulate fibroblast proliferation and may play a role in peribronchial fibrosis in chronic bronchitis.

APA, Harvard, Vancouver, ISO, and other styles

32

Pavelski, Mariana, Daniele Von Kruger Amaral, Giovana Paladino Vieira, José Francisco Warth, Rosangela Locatelli Dittrich, Peterson Triches Dornbusch, and Tilde Rodrigues Froes. "Comparative analyses of thoracic radiographs and bronchoalveolar lavage of dogs and cats with chronic bronchial diseases." Semina: Ciências Agrárias 38, no. 3 (June 13, 2017): 1403. http://dx.doi.org/10.5433/1679-0359.2017v38n3p1403.

Full text

Abstract:

There is a high incidence of bronchitis and asthma cases in veterinary medicine. Thoracic radiographs and bronchoalveolar lavage (BAL) are commonly performed for definitive diagnosis in dogs and cats with suspected bronchitis and asthma. It is believed that a combination of diagnostic tools is the best choice to achieve a diagnosis. The aim of this study was to evaluate the efficacy of thoracic radiographs and BAL in the diagnosis of chronic bronchial disease (CBD) in dogs and cats and whether there is any specific radiographic finding that could influence the indication for bronchoalveolar lavage. It was performed a cross-sectional, prospective, observational study including forty client-owned dogs and cats with lower respiratory tract signs and positive radiographic opacities that were evaluated with BAL followed by cytology and culture. The radiographic results compared with BAL culture showed a sensitivity of 38%, specificity of 95% and accuracy of 65% in detecting patients with pneumonia associated with chronic bronchial disease. Thoracic radiographs were effective in diagnosing 65% of the patients, radiographs plus BAL cytology diagnosed 75% of patients and the combination of radiographs, BAL cytology and culture diagnosed 95% of the patients with chronic bronchial disease. In conclusion, the combination of radiographic examination with BAL followed by cytological and microbiological analyses increases diagnostic success in CBD.

APA, Harvard, Vancouver, ISO, and other styles

33

Birg, N. A. "Nerve apparatus of the gastric mucosa in chronic nonspecific lung diseases and in their combination with gastroduodenal ulceration." Kazan medical journal 67, no. 1 (January 15, 1986): 45. http://dx.doi.org/10.17816/kazmj63062.

Full text

Abstract:

A total of 944 patients (557 men and 387 women) with chronic nonspecific lung diseases, mostly aged 25 to 45 years, were examined. Of these, 710 were diagnosed with chronic bronchitis, 55 with bronchiectatic disease, 92 with bronchial asthma and 87 with chronic pneumonia. Gastroduodenal ulcers were diagnosed in 76 people.

APA, Harvard, Vancouver, ISO, and other styles

34

Gurina, Olga P., Elena A. Dementeva, Aleksandr E. Blinov, Olga N. Varlamova, and Vera I. Timokhina. "IgE-hypersensitivity to allergens of the fungi Rhizopus Nigricans and Cladosporium Herbarum in childrenwith respiratory allergies." Pediatrician (St. Petersburg) 7, no. 4 (December 15, 2016): 61–66. http://dx.doi.org/10.17816/ped7461-66.

Full text

Abstract:

A survey of 111 children diagnosed with respiratory allergies (allergic rhinitis, allergic bronchitis, obstructive bronchitis, recurrent bronchitis, bronchial asthma) aged 1 year to 17 years, of which 58 children have a diagnosis of atopic bronchial asthma of different severity. All children are at risk for the development of fungal sensitization, having a household contact with these allergens. Allergological diagnostics was performed by ELISA using a panel of pediatric and fungal (Rhizopus nigricans and Cladosporium herbarum) biotinylated allergens. As a result of the study revealed that allergens mold Rhizopus nigricans and Cladosporium herbarum are the causal significant factor in the development of respiratory allergies, including asthma, in children at risk. Most often a high level of hypersensivity to Rhizopus nigricans is seen in children aged 2-5 years, Cladosporium herbarum - aged 6-9 years, concomitant to both fungal allergens at the age of 10-17 years. The correlation between the severity of atopic process and degree of sensitization to fungal allergens was not detected. All children with atopic asthma have polyvalent sensitization. Allergens mold Rhizopus nigricans and Cladosporium herbarum must be taken into account in the preparation of a diagnostic panel for children with respiratory allergies at risk. It is necessary to support drug therapy of respiratory allergy in children the activities aimed at elimination of cause significant fungal sensitization everyday surroundings.

APA, Harvard, Vancouver, ISO, and other styles

35

Plaksin, S. A., L. I. Farshatova, and A. L. Lisichkin. "Isсhemic change in bronchus stump after lung cancer resection." Grekov's Bulletin of Surgery 179, no. 3 (August 3, 2020): 33–39. http://dx.doi.org/10.24884/0042-4625-2020-179-3-33-39.

Full text

Abstract:

The OBJECTIVE of the study was to assess the changes in blood supply of the bronchus stump following lung resection with lymph node dissection.METHODS AND MATERIALS. Bronchial microcirculation was studied in 8 patients during pneumonectomy of the wall of the main bronchus using laser Doppler flowmetry method. In this paper, we present our observations of postoperative necrotic ischemic bronchitis after lobectomy with associated formation of bronchopleural fistula of the main bronchus and the failure of the stump of the lobular bronchus.RESULTS. Mobilization of the bronchus decreased microcirculation rate to (3.3±0.3) conventional units (c. u.), or to 74.5 %; lymphatic dissection further reduced microcirculation rate to (2.6±0.2) c. u., or to 60.2 %. An additional twisted suture was found to worsen ischemia. The normalized value of the amplitude decreased during the second minute of the dissection of the bronchus, indicating hypoxia. A 61-year-old patient with diabetes showed damage to the wall of the main bronchus 0.6 cm in size 7 days after undergoing the right lower lobectomy with lymphatic dissection. On the 19th day after the same procedure, the same patient developed an insolvency of the stump of the lower lobe bronchus, which was classified as a manifestation of ischemia. Postoperative ischemic bronchitis can occur in a true ischemic or an ulcerative necrotic form, and it can be diagnosed using a macroscopic picture in the context of fibrobronchoscopy. It occurs in (2.5–3.2) % of patients who underwent lung resections for cancer with lymphatic dissection.CONCLUSION. Ischemia of the bronchial wall during its mobilization plays a significant role in the etiology of bronchopleural fistula. Lymphatic dissection worsens microcirculation of the bronchial wall. Ischemic necrotic bronchitis can lead to formation of the bronchopleural fistula outside of the stump. High-risk patients require additional coverage of the bronchus stump with muscle or fat tissue.

APA, Harvard, Vancouver, ISO, and other styles

36

Yanai, M., K. Sekizawa, T. Ohrui, H. Sasaki, and T. Takishima. "Site of airway obstruction in pulmonary disease: direct measurement of intrabronchial pressure." Journal of Applied Physiology 72, no. 3 (March 1, 1992): 1016–23. http://dx.doi.org/10.1152/jappl.1992.72.3.1016.

Full text

Abstract:

To partition the central and peripheral airway resistance in awake humans, a catheter-tipped micromanometer sensing lateral pressure of the airway was wedged into the right lower lobe of a 3-mm-ID bronchus in 5 normal subjects, 7 patients with chronic bronchitis, 8 patients with emphysema, and 20 patients with bronchial asthma. We simultaneously measured mouth flow, transpulmonary pressure, and intra-airway lateral pressure during quiet tidal breathing. Total pulmonary resistance (RL) was calculated from transpulmonary pressure and mouth flow and central airway resistance (Rc) from intra-airway lateral pressure and mouth flow. Peripheral airway resistance (Rp) was obtained by the subtraction of Rc from RL. The technique permitted identification of the site of airway resistance changes. In normal subjects, RL was 3.2 +/- 0.2 (SE) cmH2O.l-1.s and the ratio of Rp to RL was 0.24 during inspiration. Patients with bronchial asthma without airflow obstruction showed values of Rc and Rp similar to those of normal subjects. Although Rc showed a tendency to increase, only Rp significantly increased in those patients with bronchial asthma with airflow obstruction and patients with chronic bronchitis and emphysema. The ratio of Rp to RL significantly increased in three groups of patients with airflow obstruction (P less than 0.01). These observations suggest that peripheral airways are the predominant site of airflow obstruction, irrespective of the different pathogenesis of chronic airflow obstruction.

APA, Harvard, Vancouver, ISO, and other styles

37

Strizh, V. A. "EFFICIENCY OF INHALATION AND PARENTAL THERAPY OF ACUTE BRONCHIAL OBSTRUCTION SYNDROME BY INFECTIOUS OR ALLERGIC GENESIS IN CHILDREN. PRINCIPLES AND TECHNIQUE OF INHALATIONS." Medical Science of Ukraine (MSU) 13, no. 1-2 (November 30, 2017): 33–40. http://dx.doi.org/10.32345/2664-4738.1-2.2017.05.

Full text

Abstract:

Relevance. Diseases of the respiratory organs occupy the first ranked place in the structure of the incidence of children, reaching 50-75 % in the regions of Ukraine. The prevalence of the syndrome of bronchial hyperactivity increases . Objective: to study the effectiveness of nebulizer therapy for relief of acute bronchial obstruction syndrome in children with exacerbation of recurrent bronchitis or bronchial asthma. Materials and methods. 52 children of school age with acute bronchial hyperactivity (recurrent bronchitis – 28, bronchial asthma – 24) were examined. Two groups were formed by randomization: the main group (27 children) and the control group (25 children). Both groups were representative by sex, age, nosological diagnosis and severity of the disease. All children received basic therapy with topical glucocorticosteroids by nebulization. Children of the main group received intensive treatment by salbutamol inhalation during the first treatment day, and on 2–5 days as in the control group only 3 times a day. Children of the control group received inhalations together with intravenous drip infusions of euphyllin and dexamethasone. Results. In both groups, there was a dynamic regression of cough and sputum excretion, but in the main group, the rate of disappearance of cough by the 5th day of treatment was 3 times, and by the 10th day – 2,3 times higher, than in the control (p < 0.05); the rate of disappearance of sputum within 10 days is 1,7 times higher, respectively (p <0.05). Positive changes were confirmed by an auscultative pattern, the normalization of which occurred earlier for 1 week in patients receiving intensive nebulization bronchodilator therapy during the first day of the treatment. Conclusions. Competent use of nebulizers allows to increase the effectiveness of treatment of children with acute bronchial obstructive syndrome. Early relief of bronchospasm promotes faster normalization of inspiratory flow and respiration recovery. As a result, the terms of recovery and length of stay of children in the hospital are shortened.

APA, Harvard, Vancouver, ISO, and other styles

38

Kim, Yoonjoo, Geon Yoo, Da-Hye Lee, Choong-Sik Lee, and Chaeuk Chung. "Spontaneous regression of incidentally diagnosed bronchial squamous cell lung carcinoma after severe bronchitis: A case report." SAGE Open Medical Case Reports 9 (January 2021): 2050313X2110106. http://dx.doi.org/10.1177/2050313x211010639.

Full text

Abstract:

Spontaneous regression of lung cancer is exceptionally rare. But there have been several intriguing cases reported in early and even advanced stages of lung cancer. Although the exact mechanism remains to be elucidated, the inflammation and immunologic response have been suggested as one of the means of spontaneous regression. Chronic inflammation is generally known to induce and aggravate tumorigenesis, but the relationship between cancer and inflammation highly depends on the contexts. Here, we present a case of a 60-year-old male ex-smoker who complained of recurrent hemoptysis, cough, and purulent sputum. The initial chest CT scan revealed diffuse bronchial thickening and an endobronchial mass-like lesion in the left lingular segment. The bronchoscopic and pathological findings also suggested a diagnosis of squamous cell carcinoma with severe mucosal inflammation. He was treated with antibiotics for the bronchitis during the first 1 week and his symptoms markedly improved. After 3 weeks, he underwent a follow-up examination. Chest computed tomography and bronchoscopy revealed the significant improvement of the bronchial narrowing and mucosal edema. Biopsy was performed several times around the lesion where the tissue was initially taken. However, the pathological results showed only chronic inflammation of bronchi, not cancer cells. Fortunately, there was no recurrence of lung cancer in follow-up chest computed tomography or bronchoscopy for almost 5 years. In this case, the incidentally diagnosed bronchial squamous cell carcinoma disappeared after severe inflammatory reaction of the bronchial wall. The clinician should remind the risk of early lung cancer accompanied with bronchitis in high-risk patients of lung cancer and also be aware that although it is very rare, the lesions could spontaneously regress.

APA, Harvard, Vancouver, ISO, and other styles

39

Barbarroja-Escudero, J., MJ Sánchez-González, A. Ruíz-Peña, RA Pérez-Labour, M. Rodríguez-Rodríguez, and M. Alvarez-Mon. "A Rare Case of Plastic Bronchitis Following Bronchial Thermoplasty." Journal of Investigational Allergology and Clinical Immunology 29, no. 4 (April 2, 2019): 331–32. http://dx.doi.org/10.18176/jiaci.0400.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Bowen, A., K. Oudjhane, K. Odagiri, SL Liston, WA Cumming, and KS Oh. "Plastic bronchitis: large, branching, mucoid bronchial casts in children." American Journal of Roentgenology 144, no. 2 (February 1985): 371–75. http://dx.doi.org/10.2214/ajr.144.2.371.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Cajaiba, Mariana M., Paula Borralho, and Miguel Reyes-Múgica. "The Potentially Lethal Nature of Bronchial Casts: Plastic Bronchitis." International Journal of Surgical Pathology 16, no. 2 (April 2008): 230–32. http://dx.doi.org/10.1177/1066896907307234.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Arnoldsson, H., A. Bouhuys, and S. E. Lindell. "Byssinosis: Differential Diagnosis from Bronchial Asthma and Chronic Bronchitis." Acta Medica Scandinavica 173, no. 6 (April 24, 2009): 761–68. http://dx.doi.org/10.1111/j.0954-6820.1963.tb17463.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Nepomnyashchikh, G. I., L. A. Naumova, and L. M. Nepomnyashchikh. "Atrophy of bronchial epithelium: Ultrastructural-metabolic analysis of the bronchial mucosa in chronic bronchitis." Bulletin of Experimental Biology and Medicine 118, no. 4 (October 1994): 1144–48. http://dx.doi.org/10.1007/bf02446481.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Stanford, Denise, Harrison Kim, Sandeep Bodduluri, Jennifer LaFontaine, Stephen A. Byzek, Trenton R. Schoeb, Elex S. Harris, et al. "Airway remodeling in ferrets with cigarette smoke-induced COPD using µCT imaging." American Journal of Physiology-Lung Cellular and Molecular Physiology 319, no. 1 (July 1, 2020): L11—L20. http://dx.doi.org/10.1152/ajplung.00328.2019.

Full text

Abstract:

Structural changes to airway morphology, such as increased bronchial wall thickness (BWT) and airway wall area, are cardinal features of chronic obstructive pulmonary disease (COPD). Ferrets are a recently established animal model uniquely exhibiting similar clinical and pathological characteristics of COPD as humans, including chronic bronchitis. Our objective was to develop a microcomputed tomography (µCT) method for evaluating structural changes to the airways in ferrets and assess whether the effects of smoking induce changes consistent with chronic bronchitis in humans. Ferrets were exposed to mainstream cigarette smoke or air control twice daily for 6 mo. µCT was conducted in vivo at 6 mo; a longitudinal cohort was imaged monthly. Manual measurements of BWT, luminal diameter (LD), and BWT-to-LD ratio (BWT/LD) were conducted and confirmed by a semiautomated algorithm. The square root of bronchial wall area (√WA) versus luminal perimeter was determined on an individual ferret basis. Smoke-exposed ferrets reproducibly demonstrated 34% increased BWT ( P < 0.001) along with increased LD and BWT/LD versus air controls. Regression indicated that the effect of smoking on BWT persisted despite controlling for covariates. Semiautomated measurements replicated findings. √WA for the theoretical median airway luminal perimeter of 4 mm (Pi4) was elevated 4.4% in smoke-exposed ferrets ( P = 0.015). Increased BWT and Pi4 developed steadily over time. µCT-based airway measurements in ferrets are feasible and reproducible. Smoke-exposed ferrets develop increased BWT and Pi4, changes similar to humans with chronic bronchitis. µCT can be used as a significant translational platform to measure dynamic airway morphological changes.

APA, Harvard, Vancouver, ISO, and other styles

45

Maksimov, N. I. "Long-term results of laser therapy in patients with bronchial asthma and chronic obstructive bronchitis." Kazan medical journal 67, no. 5 (September 15, 1986): 379–80. http://dx.doi.org/10.17816/kazmj70717.

Full text

Abstract:

We performed a course of treatment with the helium-neon laser L G-75 in the conditions of a polyclinic for patients with bronchial asthma (170 persons) and chronic obstructive bronchitis (90). Exposure to the laser beam was made taking into account the experience of reflexotherapy. Time of exposure to each biologically active point was 10 s with irradiation power of 25 mW (course - 15-20 procedures).

APA, Harvard, Vancouver, ISO, and other styles

46

Tsuchiya, K. "Environmental Health in Japan — A Retrospective and Prospective Review." Asia Pacific Journal of Public Health 1, no. 4 (October 1987): 57–65. http://dx.doi.org/10.1177/101053958700100414.

Full text

Abstract:

This paper is a review of environmental quality over recent decades in Japan. It refers to the compensation system of environmental pollution-related health impairment first. Currently, those with any of the following four diseases: respiratory diseases (chronic bronchitis; bronchial asthma; asthmatic bronchitis and pulmonary emphysema); Minamata disease; Ital-ital disease associated with cadmium poisoning; and chronic arsenic poisoning are eligible for certification to receive benefits under the Compensation Law. In addition to a brief history and description of the present situation regarding these diseases, air quality standard and compliance rate are discussed. Other environmental pollutants such as water pollution, noise and vibration are also noted. Finally, the importance of international cooperation concerning the problems of acid rain and increased carbon dioxide in the atmosphere, is discussed.

APA, Harvard, Vancouver, ISO, and other styles

47

Abd El Rahman, Sahar, Christine Winter, Ali El-Kenawy, Ulrich Neumann, and Georg Herrler. "Differential Sensitivity of Well-Differentiated Avian Respiratory Epithelial Cells to Infection by Different Strains of Infectious Bronchitis Virus." Journal of Virology 84, no. 17 (June 10, 2010): 8949–52. http://dx.doi.org/10.1128/jvi.00463-10.

Full text

Abstract:

ABSTRACT Infectious bronchitis virus (IBV) is an avian coronavirus affecting the respiratory tract of chickens. To analyze IBV infection of the lower respiratory tract, we applied a technique that uses precision-cut lung slices (PCLSs). This method allows infection of bronchial cells within their natural tissue composition under in vitro conditions. We demonstrate that IBV strains 4/91, Italy02, and QX infect ciliated and mucus-producing cells of the bronchial epithelium, whereas cells of the parabronchial tissue are resistant to infection. This is the first study, using PCLSs of chicken origin, to analyze virus infection. PCLSs should also be a valuable tool for investigation of other respiratory pathogens, such as avian influenza viruses.

APA, Harvard, Vancouver, ISO, and other styles

48

Koloskova, Olena К., Tatiana М. Bilous, Galyna A. Bilyk, Roman V. Tkachuk, and Maryana V. Dikal. "CLINICAL FEATURES OF THE COURSE AND ASSESSMENT OF TREATMENT STRATEGY IN CHILDREN WITH BRONCHITIS." Eastern Ukrainian Medical Journal 9, no. 2 (2021): 157–65. http://dx.doi.org/10.21272/eumj.2021;9(2):157-165.

Full text

Abstract:

Respiratory diseases always account for a significant proportion of visits to the pediatrician or family doctor, and bronchitis is usually a frequent clinical manifestation of acute respiratory diseases. The doctor often faces the question of how to objectively assess the clinical picture of bronchitis, and now the assessment of respiratory symptoms is often based on criteria such as cough, shortness of breath or wheezing on auscultation. However, today there are practically no data on the severity of bronchitis in children depending on the above criteria. A cohort of 158 children with bronchitis was created at the pulmonology and allergology Department of the Municipal Medical Institution "Regional Children's Clinical Hospital" in Chernivtsi. The severity of bronchitis was assessed at the beginning and on the 3rd and 7th day of inpatient using the Bronchitis Severity Score (BSS). According to this scale, mild bronchitis was verified in 30 patients which formed the I clinical group, and 128 children had moderate bronchitis (II clinical comparison group). Aggressive inflammation of the bronchi in children with moderate inflammation of the bronchial tree compared with patients with mild bronchitis was accompanied 1.6 times more often by recurrence, a history of episodes of community-acquired pneumonia in 9.4% of patients, long-term inpatient treatment (odds ratio 2.6) and halving the duration of the outpatient treatment period. The study of clinical severity of bronchitis in children of the comparison groups made it possible to establish an increase in the chances of a more severe course of the disease on the 7th day of hospitalization in children with moderate bronchitis (odds ratio 4.8) with persistence of cough in 68.7% of children in this group (odds ratio 3.8). Evaluation of inpatient treatment tactics indicated the need to increase the volume of complex therapy in patients with moderate bronchitis relative to children with mild disease (odds ratio 12.0, relative risk 8.8), as well as increasing the risk of the need for antibacterial therapy (odds ratio 3.7, relative risk 2.8) and the appointment of intravenous antibiotics for more than 3 days (odds ratio 5.0, relative risk 1.1).

APA, Harvard, Vancouver, ISO, and other styles

49

Werkhaven, Jay, and Lauren D. Holinger. "Bronchial Casts in Children." Annals of Otology, Rhinology & Laryngology 96, no. 1 (January 1987): 86–92. http://dx.doi.org/10.1177/000348948709600121.

Full text

Abstract:

Bronchial casts were found in four children during a 2-year period at the Children's Memorial Hospital. These four children represent 0.2% of the 1,943 endoscopic cases during that time. Thirty other cases of bronchial casts have been reported previously in children 9 years of age or younger, only 12 of which were not associated with cystic fibrosis. Casts may be a complication of many diseases; cystic fibrosis, asthma, bronchitis, allergic bronchopulmonary aspergillosis, and bronchocentric granulomatosis are the most common. With the exception of cystic fibrosis, these diseases may all have an allergic pulmonary reaction as the underlying cause. In all four cases reported here, the diagnosis was made at endoscopy because the clinical picture is not dissimilar from that of bronchial foreign bodies. Management includes endoscopic removal of the cast, chest physical therapy with nebulized acetylcysteine, and an evaluation to determine the underlying condition.

APA, Harvard, Vancouver, ISO, and other styles

50

Nomoto, Yoshihito, Noriko Ii, Shuichi Murashima, Yasufumi Yamashita, Satoru Ochiai, Akinori Takada, Yutaka Toyomasu, Tomoko Kawamura, and Hajime Sakuma. "Endobronchial brachytherapy with curative intent: the impact of reference points setting according to the bronchial diameter." Journal of Radiation Research 58, no. 6 (July 1, 2017): 849–53. http://dx.doi.org/10.1093/jrr/rrx031.

Full text

Abstract:

Abstract Endobronchial brachytherapy (EBB) is an effective treatment for endobronchial tumors. However, bronchial toxicity caused by over-irradiation remains problematic. To decrease bronchial toxicity, we developed a source-centralizing applicator for EBB. The purpose of the present study was to assess the efficacy and safety of EBB with varying reference dose points according to the bronchial diameter, using a source-centralizing applicator. We reviewed 15 patients with endobronchial carcinoma who were treated with curative intent using a combination of external beam radiotherapy (EBRT) and high-dose-rate EBB between 2005 and 2014. During each EBB session, we used a source-centralizing applicator that maintained the source-delivering catheter in the center of the bronchial lumen. Reference dose points were 5–7 mm from the source axis, depending on the bronchial diameter. The median radiation doses of EBRT and EBB were 40 Gy in 20 fractions and 18 Gy in 3 fractions, respectively. The median observation period was 36 months. The 3-year overall survival, progression-free survival and local control rates were 79%, 77% and 100%, respectively. Grade 2 radiation pneumonitis was observed in two cases. Bronchial toxicities, such as hemoptysis or the symptoms of chronic bronchitis, were not observed. EBB with varying reference dose points according to bronchial diameter, using a source-centralizing applicator, is a promising procedure that may be effective for tumor elimination and reducing toxicity to the bronchial wall.

APA, Harvard, Vancouver, ISO, and other styles

Journal articles on the topic 'Bronchitas'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles