Log in

Relevant bibliographies by topics / Brother Of the Regulator of Imprinted Sites / Journal articles

To see the other types of publications on this topic, follow the link: Brother Of the Regulator of Imprinted Sites.

Journal articles on the topic 'Brother Of the Regulator of Imprinted Sites'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 32 journal articles for your research on the topic 'Brother Of the Regulator of Imprinted Sites.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Chen, Kefei, Wenqing Huang, Bin Huang, et al. "BORIS, Brother of the Regulator of Imprinted Sites, Is Aberrantly Expressed in Hepatocellular Carcinoma." Genetic Testing and Molecular Biomarkers 17, no. 2 (2013): 160–65. http://dx.doi.org/10.1089/gtmb.2012.0242.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Zhang, Yanmei, Yongfei Song, Chao Li, et al. "Brother of regulator of imprinted sites inhibits cisplatin‑induced DNA damage in non‑small cell lung cancer." Oncology Letters 20, no. 5 (2020): 1. http://dx.doi.org/10.3892/ol.2020.12114.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Zambrano-Galván, Graciela, Miguel Reyes-Romero, Ronell Bologna-Molina, Oscar Eduardo Almeda-Ojeda, and Obed Lemus-Rojero. "CTCFL(BORIS) mRNA Expression in a Peripheral Giant Cell Granuloma of the Oral Cavity." Case Reports in Dentistry 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/792615.

Full text

Abstract:

Peripheral giant cell granuloma (PGCG) is a relatively common benign reactive lesion of the oral cavity which can occur at any age.CTCFL/BORIS(CTCFlike/Brother of the Regulator of Imprinted Sites) andCTCF(CCCTC-binding factor) are paralogous genes with an important role in the regulation of gene expression, genomic imprinting, and nuclear chromatin insulators regulation.BORISexpression promotes cell immortalization and growth whileCTCFhas tumor suppressor activity; the expression pattern may reflect the reverse transcription silencing ofBORIS. The aim of this work was to describe a histopathol

APA, Harvard, Vancouver, ISO, and other styles

4

Lee, Hae Young, Jong In Kim, Sung Ho Cho, et al. "Expression of the Brother of the Regulator of Imprinted Sites Gene in the Sputum of Patients with Lung Cancer." Korean Journal of Thoracic and Cardiovascular Surgery 47, no. 4 (2014): 378–83. http://dx.doi.org/10.5090/kjtcs.2014.47.4.378.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Akhtar, Mohammad Salman, Naseem Akhter, Arshi Talat, et al. "Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression." Oncotarget 14, no. 1 (2023): 528–41. http://dx.doi.org/10.18632/oncotarget.28442.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Sati, Leyla, Caroline Zeiss, Krishna Yekkala, Ramazan Demir та James McGrath. "Expression of theCTCFLGene during Mouse Embryogenesis Causes Growth Retardation, Postnatal Lethality, and Dysregulation of the Transforming Growth Factor β Pathway". Molecular and Cellular Biology 35, № 19 (2015): 3436–45. http://dx.doi.org/10.1128/mcb.00381-15.

Full text

Abstract:

CTCFL, a paralog ofCTCF, also known asBORIS(brother of regulator of imprinted sites), is a testis-expressed gene whose function is largely unknown. Its product is a cancer testis antigen (CTA), and it is often expressed in tumor cells and also seen in two benign human vascular malformations, juvenile angiofibromas and infantile hemangiomas. To understand the function ofCtcfl, we created tetracycline-inducibleCtcfltransgenic mice. We show thatCtcflexpression during embryogenesis results in growth retardation, eye malformations, multiorgan pathologies, vascular defects, and neonatal death. This

APA, Harvard, Vancouver, ISO, and other styles

7

Singh, Smriti, Sathiya Pandi Narayanan, Kajal Biswas, et al. "Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect." Proceedings of the National Academy of Sciences 114, no. 43 (2017): 11440–45. http://dx.doi.org/10.1073/pnas.1708447114.

Full text

Abstract:

Aberrant alternative splicing and epigenetic changes are both associated with various cancers, but epigenetic regulation of alternative splicing in cancer is largely unknown. Here we report that the intragenic DNA methylation-mediated binding of Brother of Regulator of Imprinted Sites (BORIS) at the alternative exon of Pyruvate Kinase (PKM) is associated with cancer-specific splicing that promotes the Warburg effect and breast cancer progression. Interestingly, the inhibition of DNA methylation, BORIS depletion, or CRISPR/Cas9-mediated deletion of the BORIS binding site leads to a splicing swi

APA, Harvard, Vancouver, ISO, and other styles

8

El-Sharkawy, Nahla M., Wafaa M. Radwan, Enas S. Essa, et al. "Increased expression of brother of the regulator of imprinted sites in peripheral blood neutrophils is associated with both benign and malignant breast lesions." Cytometry Part B: Clinical Cytometry 92, no. 5 (2016): 355–60. http://dx.doi.org/10.1002/cyto.b.21378.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Suzuki, Teruhiko, Natsuki Kosaka-Suzuki, Svetlana Pack, et al. "Expression of a Testis-Specific Form of Gal3st1 (CST), a Gene Essential for Spermatogenesis, Is Regulated by the CTCF Paralogous Gene BORIS." Molecular and Cellular Biology 30, no. 10 (2010): 2473–84. http://dx.doi.org/10.1128/mcb.01093-09.

Full text

Abstract:

ABSTRACT Previously, it was shown that the CTCF paralogous gene, BORIS (brother of the regulator of imprinted sites) is expressed in male germ cells, but its function in spermatogenesis has not been defined. To develop an understanding of the functional activities of BORIS, we generated BORIS knockout (KO) mice. Mice homozygous for the null allele had a defect in spermatogenesis that resulted in small testes associated with increased cell death. The defect was evident as early as postnatal day 21 and was manifested by delayed production of haploid cells. By gene expression profiling, we found

APA, Harvard, Vancouver, ISO, and other styles

10

Ghochikyan, Anahit, Mikayel Mkrtichyan, Dmitri Loukinov, et al. "Elicitation of T Cell Responses to Histologically Unrelated Tumors by Immunization with the Novel Cancer-Testis Antigen, Brother of the Regulator of Imprinted Sites." Journal of Immunology 178, no. 1 (2006): 566–73. http://dx.doi.org/10.4049/jimmunol.178.1.566.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Kosaka-Suzuki, Natsuki, Teruhiko Suzuki, Elena M. Pugacheva, et al. "Transcription Factor BORIS (Brother of the Regulator of Imprinted Sites) Directly Induces Expression of a Cancer-Testis Antigen, TSP50, through Regulated Binding of BORIS to the Promoter." Journal of Biological Chemistry 286, no. 31 (2011): 27378–88. http://dx.doi.org/10.1074/jbc.m111.243576.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Nguyen, Phuongmai, Gil Bar-Sela, Lunching Sun, et al. "BAT3 and SET1A Form a Complex with CTCFL/BORIS To Modulate H3K4 Histone Dimethylation and Gene Expression." Molecular and Cellular Biology 28, no. 21 (2008): 6720–29. http://dx.doi.org/10.1128/mcb.00568-08.

Full text

Abstract:

ABSTRACT Chromatin status is characterized in part by covalent posttranslational modifications of histones that regulate chromatin dynamics and direct gene expression. BORIS (brother of the regulator of imprinted sites) is an insulator DNA-binding protein that is thought to play a role in chromatin organization and gene expression. BORIS is a cancer-germ line gene; these are genes normally present in male germ cells (testis) that are also expressed in cancer cell lines as well as primary tumors. This work identifies SET1A, an H3K4 methyltransferase, and BAT3, a cochaperone recruiter, as bindin

APA, Harvard, Vancouver, ISO, and other styles

13

Renaud, S., E. M. Pugacheva, M. D. Delgado, et al. "Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors." Nucleic Acids Research 35, no. 21 (2007): 7372–88. http://dx.doi.org/10.1093/nar/gkm896.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

ChandraSekharan, Sankaran, N. Pore, and E. Klenova. "BORIS (Brother of Regulator of Imprinting Sites) as a possible new blood marker for breast cancer." European Journal of Surgical Oncology (EJSO) 35, no. 11 (2009): 1240. http://dx.doi.org/10.1016/j.ejso.2009.07.146.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Horibe, Ryota, Yoshihiko Hirohashi, Takuya Asano, et al. "Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy." PLOS ONE 12, no. 3 (2017): e0171460. http://dx.doi.org/10.1371/journal.pone.0171460.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Asano, Takuya, Yoshihiko Hirohashi, Toshihiko Torigoe, et al. "Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is involved in cervical cancer stemness and can be a target of immunotherapy." Oncotarget 7, no. 10 (2016): 11223–37. http://dx.doi.org/10.18632/oncotarget.7165.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Odgerel, Khongorzul, and Zsófia Bánfalvi. "In silico promoter analysis and expression of the BIG BROTHER gene in different organs of potato." Columella : Journal of Agricultural and Environmental Sciences 9, no. 1 (2022): 31–41. http://dx.doi.org/10.18380/szie.colum.2022.9.1.31.

Full text

Abstract:

The ubiquitin E3 ligase BIG BROTHER/ENHANCER OF DA1 (BB) gene encoding a RING finger protein was identified as a central growth regulator in Arabidopsis thaliana. It was found that BB restricts cell proliferation and promotes leaf senescence. Besides of Arabidopsis, however, the role and regulation of BB in other plant species is only sparsely known. Supposing that the BB gene, like in Arabidopsis, has an important role in the development of potato we aimed to analyse a 3.0-kb promoter sequence of the potato BB gene, StBB, in silico and study the level of StBB expression by quantitative revers

APA, Harvard, Vancouver, ISO, and other styles

18

Centrella, M., S. Casinghino, J. Kim, et al. "Independent changes in type I and type II receptors for transforming growth factor beta induced by bone morphogenetic protein 2 parallel expression of the osteoblast phenotype." Molecular and Cellular Biology 15, no. 6 (1995): 3273–81. http://dx.doi.org/10.1128/mcb.15.6.3273.

Full text

Abstract:

Transforming growth factor beta (TGF-beta), a potent regulator of bone formation, has bifunctional effects on osteoblast replication and biochemical activity that appear differentiation dependent. We now show that cell surface binding sites for TGF-beta vary markedly among fibroblasts, bone-derived cells, and highly differentiated osteosarcoma cultures from fetal rats. Expression of betaglycan and type II receptors decline relative to type I receptor expression in parallel with an increase in osteoblast-like activity, predicting that the ratio among various TGF-beta binding sites could influen

APA, Harvard, Vancouver, ISO, and other styles

19

AAPOLA, Ulla, Katja MÄENPÄÄ, Antti KAIPIA, and Pärt PETERSON. "Epigenetic modifications affect Dnmt3L expression." Biochemical Journal 380, no. 3 (2004): 705–13. http://dx.doi.org/10.1042/bj20040067.

Full text

Abstract:

Imprinted genes are expressed from a single allele due to differential methylation of maternal or paternal alleles during gametogenesis. Dnmt3L (DNA cytosine-5-methyltransferase 3 like), a member of de novo methyltransferase Dnmt3 protein family, is a regulator of maternal imprinting. In the present study, we have characterized the promoter region of the mouse Dnmt3L gene. Transient transfection assays performed with 5´-deletion promoter constructs indicated a minimal promoter area within 440 bp upstream from the translational start site. Longer promoter constructs showed decreased activity, s

APA, Harvard, Vancouver, ISO, and other styles

20

Noé, Laura, Kathleen Freson, Elke Giets, Chantal Thijs, Christine Wittevrongel, and Christel Van Geet. "Loss of Gs Activity in Platelets from Carriers with a Heterozygous Missense Mutation in the Regulator of G Protein Signaling 2 (RGS2)." Blood 112, no. 11 (2008): 2861. http://dx.doi.org/10.1182/blood.v112.11.2861.2861.

Full text

Abstract:

Abstract Regulator of G protein signaling (RGS) proteins stimulate the GTPase activity of Gα subunits of heterotrimeric G proteins, thereby negatively regulating G protein signaling. In this way, RGS2 acts as a negative regulator of Gq and Gi signaling. It has also been described as a negative regulator of Gs signaling, but via a different mechanism. It inhibits the activation of adenylyl cyclase (AC), the target molecule of Gs, by interacting with it. In olfactory neurons, it was shown that RGS2 attenuates activation of AC type III (Sinnarajah et al., Nature 2001), the main AC subtype in plat

APA, Harvard, Vancouver, ISO, and other styles

21

Zhang, Yanmei, Mengdie Fang, Yongfei Song, Juan Ren, Jianfei Fang, and Xiaoju Wang. "Brother of Regulator of Imprinted Sites (BORIS) suppresses apoptosis in colorectal cancer." Scientific Reports 7, no. 1 (2017). http://dx.doi.org/10.1038/srep40786.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Zhou, Siqi, Lian Li, Ming Zhang, Yang Qin, and Bo Li. "The function of brother of the regulator of imprinted sites in cancer development." Cancer Gene Therapy, November 14, 2022. http://dx.doi.org/10.1038/s41417-022-00556-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Rivero-Hinojosa, Samuel, Sungyun Kang, Victor V. Lobanenkov, and Gabriel E. Zentner. "Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells." Scientific Reports 7, no. 1 (2017). http://dx.doi.org/10.1038/srep41279.

Full text

Abstract:

Abstract Despite sharing the same sequence specificity in vitro and in vivo, CCCTC-binding factor (CTCF) and its paralog brother of the regulator of imprinted sites (BORIS) are simultaneously expressed in germ cells. Recently, ChIP-seq analysis revealed two classes of CTCF/BORIS-bound regions: single CTCF target sites (1xCTSes) that are bound by CTCF alone (CTCF-only) or double CTCF target sites (2xCTSes) simultaneously bound by CTCF and BORIS (CTCF&BORIS) or BORIS alone (BORIS-only) in germ cells and in BORIS-positive somatic cancer cells. BORIS-bound regions (CTCF&BORIS and BORIS-onl

APA, Harvard, Vancouver, ISO, and other styles

24

Deng, Siwei, Yuliang Feng, and Siim Pauklin. "3D chromatin architecture and transcription regulation in cancer." Journal of Hematology & Oncology 15, no. 1 (2022). http://dx.doi.org/10.1186/s13045-022-01271-x.

Full text

Abstract:

AbstractChromatin has distinct three-dimensional (3D) architectures important in key biological processes, such as cell cycle, replication, differentiation, and transcription regulation. In turn, aberrant 3D structures play a vital role in developing abnormalities and diseases such as cancer. This review discusses key 3D chromatin structures (topologically associating domain, lamina-associated domain, and enhancer–promoter interactions) and corresponding structural protein elements mediating 3D chromatin interactions [CCCTC-binding factor, polycomb group protein, cohesin, and Brother of the Re

APA, Harvard, Vancouver, ISO, and other styles

25

Janssen, Sanne Marlijn, Roy Moscona, Mounib Elchebly, et al. "BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells." Cell Death Discovery 6, no. 1 (2020). http://dx.doi.org/10.1038/s41420-019-0235-x.

Full text

Abstract:

AbstractMelanoma is among the most aggressive cancers due to its tendency to metastasize early. Phenotype switching between a proliferative and an invasive state has been suggested as a critical process for metastasis, though the mechanisms that regulate state transitions are complex and remain poorly understood. Brother of Regulator of Imprinted Sites (BORIS), also known as CCCTC binding factor-Like (CTCFL), is a transcriptional modulator that becomes aberrantly expressed in melanoma. Yet, the role of BORIS in melanoma remains elusive. Here, we show that BORIS is involved in melanoma phenotyp

APA, Harvard, Vancouver, ISO, and other styles

26

D'Arcy, Vivien, Ziedulla K. Abdullaev, Naresh Pore, et al. "The Potential of BORIS Detected in the Leukocytes of Breast Cancer Patients as an EarlyMarker ofTumorigenesis." Clinical Cancer Research, October 24, 2006. https://doi.org/10.1158/1078-0432.CCR-05-2731.

Full text

Abstract:

Purpose: Brother of the regulator of imprinted sites (BORIS) is a novel member of the cancertestis antigen gene family.These genes are normally expressed only in spermatocytes but abnormally activated in different malignancies, including breast cancer. The aim of this study was to investigate the expression of BORISin the leukocytes of breast cancer patients and the correlation between BORIS levels and clinical/pathologic variables.Experimental Design: Leukocytes were obtained from whole blood of 87 breast cancer patients and 52 donors not diagnosed with cancer. BORIS protein was detected in l

APA, Harvard, Vancouver, ISO, and other styles

27

Pugacheva, Elena. "Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions." August 1, 2015. https://doi.org/10.5281/zenodo.21405.

Full text

Abstract:

CTCF and BORIS (CTCFL), two paralogous mammalian proteins sharing nearly identical DNA binding domains, are thought to function in mutually exclusive manners in DNA binding and transcriptional regulation. In this study we show that these two proteins co-occupy a specific subset of regulatory elements consisting of clustered CTCF binding motifs (termed 2xCTSes). BORIS occupancy at 2xCTSes is largely invariant in BORIS-positive cancer cells, with the genomic pattern recapitulating the germline-specific BORIS binding to chromatin. In contrast to the single-motif CTCF target sites (1xCTSes), the 2

APA, Harvard, Vancouver, ISO, and other styles

28

Zhang, Yanmei, Mengdie Fang, Shouye Li, et al. "BTApep-TAT peptide inhibits ADP-ribosylation of BORIS to induce DNA damage in cancer." Molecular Cancer 21, no. 1 (2022). http://dx.doi.org/10.1186/s12943-022-01621-w.

Full text

Abstract:

Abstract Background Brother of regulator of imprinted sites (BORIS) is expressed in most cancers and often associated with short survival and poor prognosis in patients. BORIS inhibits apoptosis and promotes proliferation of cancer cells. However, its mechanism of action has not been elucidated, and there is no known inhibitor of BORIS. Methods A phage display library was used to find the BORIS inhibitory peptides and BTApep-TAT was identified. The RNA sequencing profile of BTApep-TAT-treated H1299 cells was compared with that of BORIS-knockdown cells. Antitumor activity of BTApep-TAT was eval

APA, Harvard, Vancouver, ISO, and other styles

29

Yadav, Sandhya, Somnath D. Bhagat, Amit Gupta, Atul Samaiya, Aasheesh Srivastava, and Sanjeev Shukla. "Dietary-phytochemical mediated reversion of cancer-specific splicing inhibits Warburg effect in head and neck cancer." BMC Cancer 19, no. 1 (2019). http://dx.doi.org/10.1186/s12885-019-6257-1.

Full text

Abstract:

Abstract Background The deregulated alternative splicing of key glycolytic enzyme, Pyruvate Kinase muscle isoenzyme (PKM) is implicated in metabolic adaptation of cancer cells. The splicing switch from normal PKM1 to cancer-specific PKM2 isoform allows the cancer cells to meet their energy and biosynthetic demands, thereby facilitating the cancer cells growth. We have investigated the largely unexplored epigenetic mechanism of PKM splicing switch in head and neck cancer (HNC) cells. Considering the reversible nature of epigenetic marks, we have also examined the utility of dietary-phytochemica

APA, Harvard, Vancouver, ISO, and other styles

30

Batista, Rita A., Jordi Moreno-Romero, Yichun Qiu, et al. "The MADS-box transcription factor PHERES1 controls imprinting in the endosperm by binding to domesticated transposons." eLife 8 (December 2, 2019). http://dx.doi.org/10.7554/elife.50541.

Full text

Abstract:

MADS-box transcription factors (TFs) are ubiquitous in eukaryotic organisms and play major roles during plant development. Nevertheless, their function in seed development remains largely unknown. Here, we show that the imprinted Arabidopsis thaliana MADS-box TF PHERES1 (PHE1) is a master regulator of paternally expressed imprinted genes, as well as of non-imprinted key regulators of endosperm development. PHE1 binding sites show distinct epigenetic modifications on maternal and paternal alleles, correlating with parental-specific transcriptional activity. Importantly, we show that the CArG-bo

APA, Harvard, Vancouver, ISO, and other styles

31

Bossi, Alessandra Maria, and Devid Maniglio. "BioMIPs: molecularly imprinted silk fibroin nanoparticles to recognize the iron regulating hormone hepcidin." Microchimica Acta 189, no. 2 (2022). http://dx.doi.org/10.1007/s00604-022-05165-0.

Full text

Abstract:

AbstractThe possibility to prepare molecularly imprinted nanoparticles from silk fibroin was recently demonstrated starting from methacrylated silk fibroin and choosing a protein as template. Here, we attempted the imprinting of fibroin-based molecularly imprinted polymers (MIPs), called bioMIPs, using as a template hepcidin that is a iron-metabolism regulator-peptide, possessing a hairpin structure. A homogeneous population (PDI < 0.2) of bioMIPs with size ~50 nm was produced. The bioMIPs were selective for the template; the estimated dissociation constant for hepcidin was KD = 3.6 ± 0.5 1

APA, Harvard, Vancouver, ISO, and other styles

32

Archer, Catherine, and Kate Delmo. "Play Is a Child’s Work (on Instagram)." M/C Journal 26, no. 2 (2023). http://dx.doi.org/10.5204/mcj.2952.

Full text

Abstract:

Introduction Where children’s television once ruled supreme as a vehicle for sales of kids’ brands, the marketing of children’s toys now often hinges on having the right social media influencer, many of them children themselves (Verdon). As Forbes reported in 2021, the pandemic saw an increase in children spending more time online, many following their favourite influencers on YouTube, TikTok, and Instagram. The importance of tapping into partnering with the right influencer grew, as did sales in toys for children isolated at home. We detail, through a case study approach and visual narrative

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!