Relevant bibliographies by topics / Bruce (donor)

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Academic literature on the topic 'Bruce (donor)'

Author: Grafiati
Published: 4 June 2021
Last updated: 9 February 2022

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Journal articles on the topic "Bruce (donor)"

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Zhu, Eryu, Bin Wang, Dongqi Wei, and Li Zhu. "Experiment and Numerical Simulation of Wooden Door Frame." Advances in Materials Science and Engineering 2021 (September 14, 2021): 1–11. http://dx.doi.org/10.1155/2021/9964563.

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To prevent the wooden door frame of traditional rural houses from being stuck due to diamond deformation under earthquake and improve the seismic capacity of rural houses, an innovative method of reinforcing the angular displacement of the wooden door frame with channel steel and the diagonal brace is proposed. The rationality of the finite element simulation is demonstrated by comparing the results of finite element simulation and quasistatic test based on reinforced and unreinforced wooden door frame specimens. On the basis of the finite element model of wooden door frame, the seismic performance of channel type and diagonal brace thickness of reinforced wooden door frame and the seismic performance of friction coefficient of unreinforced wooden door frame are studied, respectively. The results show that the lateral stiffness and the lateral bearing capacity of the reinforced wooden door frame increase with the increase of channel steel type and the diagonal brace thickness. The height of the channel steel section of the seismic reinforcement structure should be half of the unreinforced structure. With the increase of the friction coefficient, the lateral bearing capacity of the unreinforced wooden frame increases, while the ductility of the unreinforced wooden frame decreases.
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Lenardo, M. J., D. M. Dorfman, and J. E. Donelson. "The spliced leader sequence of Trypanosoma brucei has a potential role as a cap donor structure." Molecular and Cellular Biology 5, no. 9 (1985): 2487–90. http://dx.doi.org/10.1128/mcb.5.9.2487.

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Trypanosoma brucei brucei and other trypanosomatid species are unique among eucaryotes because transcription of their protein-coding genes is discontinuous. The 5' ends of their mRNAs consist of an identical 35-nucleotide spliced leader which is encoded at a separate locus from that for the body of the protein-coding transcript. We show here that the spliced leader transcript contains a 5' cap structure and suggest that at least one function of the spliced leader sequence is to provide a cap structure to trypanosome mRNAs.
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Lenardo, M. J., D. M. Dorfman, and J. E. Donelson. "The spliced leader sequence of Trypanosoma brucei has a potential role as a cap donor structure." Molecular and Cellular Biology 5, no. 9 (1985): 2487–90. http://dx.doi.org/10.1128/mcb.5.9.2487-2490.1985.

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Trypanosoma brucei brucei and other trypanosomatid species are unique among eucaryotes because transcription of their protein-coding genes is discontinuous. The 5' ends of their mRNAs consist of an identical 35-nucleotide spliced leader which is encoded at a separate locus from that for the body of the protein-coding transcript. We show here that the spliced leader transcript contains a 5' cap structure and suggest that at least one function of the spliced leader sequence is to provide a cap structure to trypanosome mRNAs.
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Becker, Stuart D., and Jane L. Hurst. "Female behaviour plays a critical role in controlling murine pregnancy block." Proceedings of the Royal Society B: Biological Sciences 276, no. 1662 (2009): 1723–29. http://dx.doi.org/10.1098/rspb.2008.1780.

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Exposure of recently mated female rodents to unfamiliar male scents during daily prolactin surges results in pregnancy failure (the ‘Bruce effect’). Control of nasal contact with male scents during these narrow windows of sensitivity could allow females to maintain or terminate pregnancy, but female behavioural changes specifically during this critical period have not been investigated. We examined the approach or avoidance of familiar stud strain and unfamiliar male scents by recently mated female mice. Females that maintained pregnancy avoided both unfamiliar and familiar male scent during critical periods of susceptibility for the Bruce effect. By contrast, females that did not maintain pregnancy showed a sharp rise in the time spent with unfamiliar male scent during this critical period. Manipulation of the social status of unfamiliar and stud strain scent donors did not affect the likelihood of pregnancy block, although females spent more time with dominant male scents across all time periods. The ability to control the Bruce effect through behaviour during brief sensitivity just before dusk, when females are likely to be in nest sites, provides a mechanism by which females may adjust their reproductive investment according to nest site social stability and likelihood of offspring survival.
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Izquierdo, Luis, Benjamin L. Schulz, João A. Rodrigues, et al. "Distinct donor and acceptor specificities of Trypanosoma brucei oligosaccharyltransferases." EMBO Journal 28, no. 17 (2009): 2650–61. http://dx.doi.org/10.1038/emboj.2009.203.

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Furlow, Bryant. "US NICUs and donor milk banks brace for COVID-19." Lancet Child & Adolescent Health 4, no. 5 (2020): 355. http://dx.doi.org/10.1016/s2352-4642(20)30103-6.

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Izquierdo, Luis, Angela Mehlert, and Michael AJ Ferguson. "The lipid-linked oligosaccharide donor specificities of Trypanosoma brucei oligosaccharyltransferases." Glycobiology 22, no. 5 (2012): 696–703. http://dx.doi.org/10.1093/glycob/cws003.

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Pontes de Carvalho, L. C., S. Tomlinson, F. Vandekerckhove, et al. "Characterization of a novel trans-sialidase of Trypanosoma brucei procyclic trypomastigotes and identification of procyclin as the main sialic acid acceptor." Journal of Experimental Medicine 177, no. 2 (1993): 465–74. http://dx.doi.org/10.1084/jem.177.2.465.

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Here we report the presence of a trans-sialidase on the surface of Trypanosoma brucei culture-derived procyclic trypomastigotes. The enzyme is not detected in lysates of bloodstream trypomastigotes enriched for either stumpy or slender forms. The trans-sialidase catalyzes the transfer of alpha(2-3)-linked sialic acid residues to lactose. beta-galactopyranosyl residues are at least 100 times better acceptors for sialic acid than alpha-galactopyranosyl residues. In the absence of efficient acceptors, the purified enzyme transfers sialic acid to water, i.e., it acts as a sialidase. Although the T. cruzi and T. brucei trans-sialidases have very similar donor and acceptor specificities, they are antigenically distinct. Sodium dodecyl sulfate-polyacramide gel electrophoresis under nonreducing conditions and silver staining of the purified trans-sialidase reveals a single band of 63 kD. When the surface membrane of live procyclic trypomastigotes is trans-sialylated, using radioactive sialyllactose as the donor substrate, it appears that the only sialylated surface molecule is procyclin. Pronase treatment of live parasites removes only part of the surface sialic acid, in agreement with recent data showing that the glycosylphosphatidylinositol anchor of procyclin is sialylated (Ferguson, M. A. J., M. Murray, H. Rutherford, and M. J. McConville. 1993. Biochem. J. In press).
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Hall, Belinda S., Emma Louise Meredith, and Shane R. Wilkinson. "Targeting the Substrate Preference of a Type I Nitroreductase To Develop Antitrypanosomal Quinone-Based Prodrugs." Antimicrobial Agents and Chemotherapy 56, no. 11 (2012): 5821–30. http://dx.doi.org/10.1128/aac.01227-12.

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ABSTRACTNitroheterocyclic prodrugs are used to treat infections caused byTrypanosoma cruziandTrypanosoma brucei. A key component in selectivity involves a specific activation step mediated by a protein homologous with type I nitroreductases, enzymes found predominantly in prokaryotes. Using data from determinations based on flavin cofactor, oxygen-insensitive activity, substrate range, and inhibition profiles, we demonstrate that NTRs fromT. cruziandT. bruceidisplay many characteristics of their bacterial counterparts. Intriguingly, both enzymes preferentially use NADH and quinones as the electron donor and acceptor, respectively, suggesting that they may function as NADH:ubiquinone oxidoreductases in the parasite mitochondrion. We exploited this preference to determine the trypanocidal activity of a library of aziridinyl benzoquinones against bloodstream-formT. brucei. Biochemical screens using recombinant NTR demonstrated that several quinones were effective substrates for the parasite enzyme, havingKcat/Kmvalues 2 orders of magnitude greater than those of nifurtimox and benznidazole. In tests againstT. brucei, antiparasitic activity mirrored the biochemical data, with the most potent compounds generally being preferred enzyme substrates. Trypanocidal activity was shown to be NTR dependent, as parasites with elevated levels of this enzyme were hypersensitive to the aziridinyl agent. By unraveling the biochemical characteristics exhibited by the trypanosomal NTRs, we have shown that quinone-based compounds represent a class of trypanocidal compound.
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Patzelt, E., K. L. Perry, and N. Agabian. "Mapping of branch sites in trans-spliced pre-mRNAs of Trypanosoma brucei." Molecular and Cellular Biology 9, no. 10 (1989): 4291–97. http://dx.doi.org/10.1128/mcb.9.10.4291.

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The process of trans splicing is essential to the maturation of all mRNAs in the Trypanosomatidae, a family of protozoan parasites, and to specific mRNAs in several species of nematode. In Trypanosoma brucei, a 39-nucleotide (nt) leader sequence originating from a small, 139-nt donor RNA (the spliced leader [SL] RNA) is spliced to the 5' end of mRNAs. An intermediate in this trans-splicing process is a Y structure which contains the 3' 100 nt of the SL RNA covalently linked to the pre-mRNA via a 2'-5' phosphodiester bond at the branch point residue. We mapped the branch points in T. brucei alpha- and beta-tubulin pre-mRNAs. The primary branch acceptors for the alpha- and beta-tubulins are 44 and 56 nt upstream of the 3' splice sites, respectively, and are A residues. Minor branch acceptors were detected 42 and 49 nt upstream of the alpha-tubulin splice site and 58 nt upstream of the splice site in beta-tubulin. The regions surrounding these branch points lack homology to the consensus sequences determined for mammalian cells and yeasts; there is also no conservation among the sequences themselves. Thus, the identified sequences suggest that the mechanism of branch point recognition in T. brucei differs from the mechanism of recognition by U2 RNA that has been proposed for other eucaryotes.
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Dissertations / Theses on the topic "Bruce (donor)"

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Tanh, Jeazet Harold Brice [Verfasser]. "Metallo-supramolecular architectures based on multifunctional N-donor ligands / von Harold Brice Tanh Jeazet." 2010. http://d-nb.info/1008673072/34.

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Books on the topic "Bruce (donor)"

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Mourek, Anthony J. Famous, infamous & forgotten: Political cartoons from the collection of Anthony J. Mourek : exhibited from 14 November 2013 through 10 January 2014, The Grolier Club, in the City of New York, MMXIII. Grolier Club, 2013.

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Wright, Bruce. Love hangs upon an empty door: The poetry of Bruce Wright. Barricade Books, 1998.

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Book chapters on the topic "Bruce (donor)"

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Rosenstein, Donald L., and Justin M. Yopp. "Dating 2.0." In The Group. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190649562.003.0017.

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When Lisa created her family rules shortly before her death, she wrote them for her three daughters. She wanted the girls to remain close and look out for each other during the difficult days that would lie ahead. However, Bruce realized immediately that Lisa’s rules were meant for his benefit as well. The last rule was unambiguous: . . . Support Dad when he is ready to date. He is going to need it. . . . Lisa wanted Bruce to find happiness again and did her part to make that possible. Early on, Bruce had no interest in dating and felt disloyal to Lisa for even wanting companionship. After the one-year anniversary of her death, and with Lisa’s explicit approval, Bruce reached out to an old friend who had offered to set him up. A lunch date was scheduled for the following week. As the date approached, Bruce began to doubt himself. That morning, he tried to stay busy around the office, but as lunchtime neared, he panicked. He hurried down the hallway toward the office of a co-worker with whom he had become close since Lisa’s death. “I can’t go through with it!” Bruce said as he burst through the door. “Whoa, what’s going on?” his friend asked. “I’m not ready for this. I don’t know what the hell I was thinking. To go on an actual date!?! It’s too soon.” “Okay, just calm down. Have a seat and we’ll figure it out.” Bruce continued to pace around the room. “Seriously, how can I have lunch with another woman and act like it’s okay. It isn’t. I was with Lisa for almost twenty years. I don’t want to be with anyone else.” “I thought that she wanted you to date again.” “I know, I know. But how am I supposed to act … what am I supposed to talk about the whole time? That’s it. I’m not doing it.” Grabbing Bruce by the shoulders, his friend looked him in the eyes. “Get yourself together, man! I know this is hard, but you’ve got to calm down.
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Clevenger, Morgan R. "Senior Leaders as Effective Fundraisers." In Facilitating Higher Education Growth through Fundraising and Philanthropy. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-4666-9664-8.ch004.

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Funding in higher education continues to be volatile and complex, so senior leaders must focus on fundraising among a host of other key roles (Bornstein, 2003, 2011; Cheng, 2011; Clevenger, 2014; Cohen, 2010; Drezner & Huels, 2014; Essex & Ansbach, 1993; Gould, 2003; Hodson, 2010; Kaufman, 2004; Rhodes, 2001; Tromble, 1998). The goal is creating win-win relationships with a donor and the institution (Bornstein, 2003, 2011; Bruch & Walter, 2005; Carroll & Buchholtz, 2015; Clevenger; Eddy, 2010; Levy, 1999; Prince & File, 2001; Siegel, 2012). There is “a new ecology—a context deeply different from that in which many of today's institutions, assumptions, and habits were formed” (Fulton & Blau, 2005, p. 4). Senior leaders must have a toolbox filled with expertise to be effective fundraisers.
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Rosenstein, Donald L., and Justin M. Yopp. "Winding Down." In The Group. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190649562.003.0024.

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From the beginning the men had known, better than we did, that six sessions would not be enough. Changing the group to an open-ended format had been the right move, but we hadn’t resolved the question of when the group should end. The fathers were clearly piecing their lives back together and the reasons for continuing to meet were becoming less clear. As the group approached the three-year mark, attendance lagged. We wondered if it had run its course. One evening, we asked the men whether they wanted to keep meeting or if it was time to stop. We acknowledged that our work together had become increasingly collaborative but wanted them to know that they were not beholden to us. We never intended for the group to continue in perpetuity. Our focus had been to help them grieve and move forward. If they had reached that point, then they should to feel free to leave. The fathers seemed surprised when we raised this topic. They quickly dismissed the idea that they felt obligated to remain in the group. Uncharacteristically, Russ spoke first, “I’ve never felt pressured. I come because it helps.” The topic of discussion during that session was whether it was time to stop meeting. Each father knew that he would eventually leave but up until that moment Steve’s departure had been the only other occasion on which we discussed endings. Bruce reframed the issue: “Unless getting engaged and moving across state lines is the only ticket out the door, I guess we need to figure this out.” Karl approached the subject with his typical analytical style. “It sounds like there are two issues on the table. First, how does any one of us know when it’s time to stop coming? For Steve, it was easy: He got married and moved away. For the rest of us, the decision comes down to whether coming here is still helpful. Obviously, each of us has to answer that for ourselves. The second question is whether it’s time for the group as a whole to end.
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Bennett, Peggy D. "Gumption, grit, and gaiety." In Teaching with Vitality. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190673987.003.0087.

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The alliteration is appealing, and so are the images. What would happen if we took gumption, grit, and gaiety to school with us each day? Gumption is courage to act using common sense. We have a get- up- and- go attitude. We display a spirited initiative to get things done. We have drive and heart. • We may speak up calmly to disagree with a co- worker. • We may let a custodian know that we need a change in our room setup and cleaning schedule. • We may ask the principal to explain a statement made in our annual evaluation. Grit is tenacity that borders on stubbornness. We see a chal­lenge, we take it on, and we endure. With our firmness of charac­ter, challenging situations fuel us. We are persistent. • We are determined help a student achieve a challenge that baffles him. • We persevere past our threshold of fatigue and a myriad of obstacles to manage and polish the annual program for parents. • We know our weaknesses, and we are willing to do what is necessary to develop and improve. Gaiety is joyfulness, lightheartedness, and the jollification of life’s moments. We find opportunities to be joyful, and liberate ourselves to feel and show our delight. • Instead of scolding a student for an outburst, we may offer a good- natured quip instead. • We may help a colleague see the humor in an event that she found disturbing. • As we walk in the door of our school, we treat those hallowed halls as possibilities for experiencing joy and delight. These three G’s brace us for what needs to be done, drive us to complete our task, and spur us to be exultant about achieve­ments large and small. They bolster us to teach with vitality!
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