Academic literature on the topic 'Brucine Derivatives'

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Journal articles on the topic "Brucine Derivatives"

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Neganova, Margarita, Yulia Aleksandrova, Alexandra Voloshina, et al. "Biological Activity Evaluation of Phenolic Isatin-3-Hydrazones Containing a Quaternary Ammonium Center of Various Structures." International Journal of Molecular Sciences 25, no. 20 (2024): 11130. http://dx.doi.org/10.3390/ijms252011130.

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A series of new isatin-3-hydrazones bearing different ammonium fragments was synthesized by a simple and easy work-up reaction of Girard’s reagents analogs with 1-(3,5-di-tert-butyl-4-hydroxybenzyl)isatin. All derivatives have been shown to have antioxidant properties. In terms of bactericidal activity against gram-positive bacteria, including methicillin-resistant strains of Staphylococcus aureus, the best compounds are 3a, 3e, and 3m, bearing octyl, acetal, and brucine ammonium centers, respectively. In addition, brucine and quinine derivatives 3l, and 3j exhibit platelet antiaggregation act
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Figueroa-Valverde, Lauro, Francisco Díaz-Cedillo, Elodia García-Cervera, et al. "Design and Synthesis of Two Brucine Derivatives." Asian Journal of Chemistry 25, no. 12 (2013): 6783–86. http://dx.doi.org/10.14233/ajchem.2013.14674.

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Figueroa-Valverde, Lauro, Francisco Díaz-Cedillo, Elodia Garcia-Cervera, Maria Lopez-Ramos, and Eduardo Pool-Gomez. "A Facile Synthesis of Two Brucine-Steroid Derivatives." Asian Journal of Chemistry 25, no. 4 (2013): 1901–4. http://dx.doi.org/10.14233/ajchem.2013.13214.

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Davis, M., NPB Dudman та HF White. "Preparation of (S)-3-Azidodihydrofuran-2(3H)-one(α-Azidobutyrolactone) (1), a Useful Chiral Synthon". Australian Journal of Chemistry 38, № 4 (1985): 621. http://dx.doi.org/10.1071/ch9850621.

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(S)-3-Azidodihydrofuran-2(3H)-one (α- Azidobutyrolactone ) (1) has been resolved through the brucine salt of the corresponding hydroxy acid (2). Both (1), and various derivatives of (2), are useful synthons for the preparation of L-amino acids related to L- homoserine.
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Çapan, İrfan, and Süleyman Servi. "Synthesis of New C2-Symmetric Chiral Benzimidazole Derivatives Having Norbornene/Dibenzobarrelene Skeletons." Letters in Organic Chemistry 17, no. 10 (2020): 801–5. http://dx.doi.org/10.2174/1570178616666190731105327.

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Racemic dicarboxylic acids were synthesized from the Diels-Alder cycloaddition reactions which formed the dibenzobarrelene and norbornene skeletons. The pure enantiomers of these compounds were obtained using brucine as the chiral auxiliary. Novel C2-symmetric chiral benzimidazole derivatives were synthesized from the reaction of the diaminobenzene and enantiomeric dicarboxylic acids in the presence of boric acid.
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Gharagozloo, Parviz, Sebastian Lazareno, Angela Popham, and Nigel J. M. Birdsall. "Allosteric Interactions of Quaternary Strychnine and Brucine Derivatives with Muscarinic Acetylcholine Receptors." Journal of Medicinal Chemistry 42, no. 3 (1999): 438–45. http://dx.doi.org/10.1021/jm970799y.

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Mudhgi, Priya, Brijendra Singh Tomar, and Satbir Kumar Chawla. "Therapeutic Properties of Kuchala – A Short Review." International Research Journal of Ayurveda & Yoga 7, no. 7 (2024): 32–36. http://dx.doi.org/10.48165/irjay.2024.70706.

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Medicinal plants are a pool of organically active compounds. In texts, there are various allusions to the use of vishdraya as a medicine. Kuchala (Strychnos nux-vomica Linn), an evergreen tree, commonly known as poison nut is attributed with both poisonous and medicinal values. Alkaloids are the main bioactive ingredients in S. nux-vomica Linn, 80% of which are strychnine and brucine, as well as their derivatives such as brucine N-oxide or isostrychnine. In Ayurveda, it has been used for curing various ailments including paralysis, dyspepsia, itching, joint pain, dysentery, emotional disorders
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Kirubakarababu, Merlin, and Arputharaj Samson Nesaraj. "Transition of Therapeutic to Toxicological Effects of Certain Plant Alkaloids: A Critical Review Based on their Forensic Perspective." Asian Journal of Chemistry 34, no. 7 (2022): 1613–24. http://dx.doi.org/10.14233/ajchem.2022.23604.

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The secondary metabolites have a significant property of therapy as well as toxicity. One among the secondary metabolite that is enormously present in plants is alkaloids. The occurrence of the alkaloid is found to be about 20% in the plants. These compounds have a useful therapeutic application in health disorders. On the other hand, they also cause toxicity to humans as well as animals. Their toxicity levels in humans may tend to affect the gastrointestinal and nervous systems. In this review, occurrence, synthesis and the toxicity levels of non-heterocyclic alkaloids viz. N-methyl tyramine
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DEHMLOW, E. V., and M. S. ROMERO. "ChemInform Abstract: Applications of Phase-Transfer Catalysis. Part 56. Experiments with Some (-)-Sparteine and (-)-Brucine Derivatives as Phase-Transfer Catalysts." ChemInform 24, no. 14 (2010): no. http://dx.doi.org/10.1002/chin.199314050.

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Figueroa-V, L., F. Diaz-Cedil, E. Garcia-Cer, et al. "Antimicrobial Activity Induced by A Steroid-brucine Derivative on S. typhi, K. pneumoniae and E. coli." Journal of Biological Sciences 14, no. 1 (2013): 67–72. http://dx.doi.org/10.3923/jbs.2014.67.72.

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Dissertations / Theses on the topic "Brucine Derivatives"

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Li, Jian-yuan. "The modification of brucine derivatives as chiral ligands and its application in the asymmetric synthesis." Thesis, 2014. http://hdl.handle.net/1805/6464.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>The modification of brucine derivatives as chiral ligands and the use of a multifaceted chiral ligand, brucine diol, under different reaction conditions to produce various optical isomers is described. In Chapter 1, the generation of a number of brucine derivatives is described. Taking the advantage of brucine-diol’s excellent molecular recognition capability for multiple organic functional groups, we focused on the synthetic modifications of brucine-diol and the synthesis of brucine N-oxide. We also produced various brucine derivati
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Book chapters on the topic "Brucine Derivatives"

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Taber, Douglass. "Enantioselective Construction of Alkylated Stereogenic Centers." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0038.

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The enantioselectivity of alkene reduction usually depends on the geometric purity of the alkene. Bruce H. Lipshutz of the University of California, Santa Barbara used ( Organic Lett. 2007, 9, 4713) carboalumination of the alkyne 1 to prepare 2, which was selectively reduced to 3 in high ee. André B. Charette of the Université de Montréal reported ( Angew. Chem. Int. Ed. 2007, 46, 5955) a related reduction of unsaturated sulfones such as 4. Juan C. Carretero of the Universidad Autónoma de Madrid has developed ( J. Org. Chem. 2007, 72, 9924) a complementary route to enantiomerically-enriched su
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