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Journal articles on the topic 'Brushite cements'

Author: Grafiati

Published: 26 September 2023

Last updated: 31 July 2025

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1

No, Young Jung, Ib Holzmeister, Zufu Lu, et al. "Effect of Baghdadite Substitution on the Physicochemical Properties of Brushite Cements." Materials 12, no. 10 (2019): 1719. http://dx.doi.org/10.3390/ma12101719.

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Brushite cements have been clinically used for irregular bone defect filling applications, and various strategies have been previously reported to modify and improve their physicochemical properties such as strength and injectability. However, strategies to address other limitations of brushite cements such as low radiopacity or acidity without negatively impacting mechanical strength have not yet been reported. In this study, we report the effect of substituting the beta-tricalcium phosphate reactant in brushite cement with baghdadite (Ca3ZrSi2O9), a bioactive zirconium-doped calcium silicate

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2

Aghyarian, Shant, Lucas C. Rodriguez, Jonathan Chari, et al. "Characterization of a new composite PMMA-HA/Brushite bone cement for spinal augmentation." Journal of Biomaterials Applications 29, no. 5 (2014): 688–98. http://dx.doi.org/10.1177/0885328214544770.

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Calcium phosphate fillers have been shown to increase cement osteoconductivity, but have caused drawbacks in cement properties. Hydroxyapatite and Brushite were introduced in an acrylic two-solution cement at varying concentrations. Novel composite bone cements were developed and characterized using rheology, injectability, and mechanical tests. It was hypothesized that the ample swelling time allowed by the premixed two-solution cement would enable thorough dispersion of the additives in the solutions, resulting in no detrimental effects after polymerization. The addition of Hydroxyapatite an

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3

Lilley, K. J., Uwe Gbureck, Adrian J. Wright, David Farrar, and J. E. Barralet. "Investigation into Carboxylic Acids as Cement Reactants." Key Engineering Materials 309-311 (May 2006): 853–56. http://dx.doi.org/10.4028/www.scientific.net/kem.309-311.853.

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Bajpai et al. originally reported the formation of cements by the mixture of carboxylic acids and β-tricalcium phosphate (β-TCP). In the current study, we report and contrast four such cement systems formed from mixing citric, malic, 2-oxoglutaric or phosphoric acid with β-TCP. Cements formed from malic or 2-oxoglutaric appeared to contain crystalline phases and were determined to contain brushite, β-TCP and unreacted acid. In contrast, cement formed with citric acid was poorly crystalline, containing little evidence of brushite formation and was unstable in water and therefore does not appear

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4

Altundal, Sahin, Marco Laurenti, Enrique Jose López‐Cabarcos, Jorge Rubio-Retama, and Karlis Agris Gross. "Accelerated Transformation of Brushite Cement into Carbonate Apatite in Biomimetic Solution." Key Engineering Materials 800 (April 2019): 70–74. http://dx.doi.org/10.4028/www.scientific.net/kem.800.70.

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Brushite cement has advantages such as fast setting, high reactivity and good injectability over apatitic cements. To induce the bioactivity of brushite cements, the goal was to convert it into a bone-like low crystalline carbonate apatite. To achieve this induced transformation, potassium and magnesium were used as dopants which were claimed to be effective in the literature. The cements were immersed for 2 periods of time: 1 day and 6 weeks in Tas-Simulated-Body-Fluid (Tas-SBF) due to its excellent biomimetic properties with its adjusted HCO3- and Cl- ionic rates according to human-blood-pla

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5

Fadeeva, I. V., Shachnoza Fuzailova, I. V. Dudenkov, et al. "Brushite boron cement with antibacterial properties." Perspektivnye Materialy 4 (2024): 31–37. http://dx.doi.org/10.30791/1028-978x-2024-4-31-37.

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Boron-containing brushite cements (B-BC) for bone grafting based on B-substituted β-tricalcium phosphate (B-TCP) have been developed. The phase composition and microstructure of B-BC have been studied. It is shown that the crystalline phase of brushite is formed as a result of hardening of cements. The behavior of B-BC in physiological solution containing TRIS-buffer was studied. The strength of B-BC under compression 5 days after mixing is 22.5 ± 1 MPa. Studies of antibacterial activity against gram-negative strain E. coli ATCC25922 and gram-positive strain S. aureus ATCC25923 showed that bor

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6

Srakaew, N., and Sirirat T. Rattanachan. "Effect of Apatite Wollastonite Glass Ceramic Addition on Brushite Bone Cement Containing Chitosan." Advanced Materials Research 506 (April 2012): 106–9. http://dx.doi.org/10.4028/www.scientific.net/amr.506.106.

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Apatite wollastonite glass ceramic (AW-GC) (34.2% SiO2, 44.9% CaO, 16.3%P2O5, 4.6% MgO, 0.5% CaF2) was added into a brushite bone cement, which composed of β-tricalcium phosphate (β-Ca3(PO4)2, β-TCP) and monocalcium phosphate monohydrate (Ca (H2PO4)2H2O, MCPM) in powder phases. Cement was prepared using a 3 β-TCP:2 MCPM in weight ratio. To evaluate the effect of AW-GC on the mechanical strength and degradability of brushite bone cement, the powder phases and 1 wt.% of chitosan dissolved in 5 wt.% of citric acid solution were mixed and soaked in simulated body fluid solution at 37 °C for 1, 3,

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7

Grover, Liam M., Sarika Patel, Y. Hu, Uwe Gbureck, and J. E. Barralet. "Modifying Brushite Cement Degradation Using Calcium Alginate Beads." Key Engineering Materials 361-363 (November 2007): 311–14. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.311.

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The hydrolysis of brushite in calcium phosphate cements to form hydroxyapatite is known to result in the long term stability of the material in the body. It has previously been established that this hydrolysis reaction can be influenced by implant volume, media refreshment rate and media composition. In this study, the effect of macroporosity on the rate of degradation of the material is investigated. Macroporosity was incorporated into the material using calcium alginate beads mixed into the cement paste. The inclusion of the calcium alginate beads did not influence the degree of conversion o

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8

Alkhraisat, Mohammad Hamdan, Jatsue Cabrejos-Azama, Carmen Rueda Rodríguez, Luis Blanco Jerez, and Enrique López Cabarcos. "Magnesium substitution in brushite cements." Materials Science and Engineering: C 33, no. 1 (2013): 475–81. http://dx.doi.org/10.1016/j.msec.2012.09.017.

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9

Bohner, M., and U. Gbureck. "Thermal reactions of brushite cements." Journal of Biomedical Materials Research Part B: Applied Biomaterials 84B, no. 2 (2008): 375–85. http://dx.doi.org/10.1002/jbm.b.30881.

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10

Mahmood, S., W. M. Palin, Uwe Gbureck, O. Addison, and M. P. Hofmann. "Effect of Mechanical Mixing and Powder to Liquid Ratio on the Strength and Reliability of a Brushite Bone Cement." Key Engineering Materials 361-363 (November 2007): 307–10. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.307.

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The effect of mechanical mixing on compressive strength, relative porosity and reliability of strength data of a brushite forming cement at different powder to liquid ratios (PLRs) was investigated. Mean compressive strengths were measured, associated reliability (Weibull moduli) and survival probability distributions of the data sets were analysed. Relative porosities were determined using helium pycnometry. For low PLR (2.2g/ml), no significant differences in compressive strength were observed for either mechanical or hand mixed samples, although reliability of the former was significantly i

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11

Tamimi, Faleh, Zeeshan Sheikh, and Jake Barralet. "Dicalcium phosphate cements: Brushite and monetite." Acta Biomaterialia 8, no. 2 (2012): 474–87. http://dx.doi.org/10.1016/j.actbio.2011.08.005.

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12

Geffers, Martha, Jake E. Barralet, Jürgen Groll, and Uwe Gbureck. "Dual-setting brushite–silica gel cements." Acta Biomaterialia 11 (January 2015): 467–76. http://dx.doi.org/10.1016/j.actbio.2014.09.036.

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13

Irbe, Zilgma, Linda Vecbiskena, and Liga Berzina-Cimdina. "Setting Properties of Brushite and Hydroxyapatite Compound Cements." Advanced Materials Research 222 (April 2011): 239–42. http://dx.doi.org/10.4028/www.scientific.net/amr.222.239.

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In this work properties of potential brushite (CaHPO4•2H2O) and hydroxyapatite (Ca10(PO4)6(OH)2) compound cements are investigated. Calcium dihydrogenphosphate monohydrate (MCPM) and α-tricalcium phosphate (α-TCP) were the starting materials for investigated cements. Setting time is controlled by adding setting time retarder – citrate ions and initially unreactive filler - monetite (CaHPO4). Some compositions of obtained cements contain both brushite and hydroxyapatite. However a substantial amount of monetite was present even if it is not added as filler. There is a strong evidence of presenc

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14

Bini, Marcella, Giovanna Bruni, Michela Sturini, et al. "Pure and Doped Brushite Cements Loaded with Piroxicam for Prolonged and Constant Drug Release." Materials 18, no. 5 (2025): 1065. https://doi.org/10.3390/ma18051065.

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The increase in life expectancy has led to a rise of musculoskeletal disorders. Calcium phosphate cements (CPCs), thanks to some amazing features such as the ability to harden in vivo, bioactivity, and resorbability, are promising candidates to treat these diseases, notwithstanding their poor mechanical properties. We aimed to synthesise pure and barium- or silicon-doped brushite-based CPCs loaded with piroxicam to study the effects of the substitution on physical-chemical and pharmaceutical properties before and after cement immersion in phosphate buffer for different time periods. Our result

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15

Giocondi, Jennifer L., Bassem S. El-Dasher, George H. Nancollas, and Christine A. Orme. "Molecular mechanisms of crystallization impacting calcium phosphate cements." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 368, no. 1917 (2010): 1937–61. http://dx.doi.org/10.1098/rsta.2010.0006.

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The biomineral calcium hydrogen phosphate dihydrate (CaHPO 4 ·2H 2 O), known as brushite, is a malleable material that both grows and dissolves faster than most other calcium minerals, including other calcium phosphate phases, calcium carbonates and calcium oxalates. Within the body, this ready formation and dissolution can play a role in certain diseases, such as kidney stone and plaque formation. However, these same properties, along with brushite’s excellent biocompatibility, can be used to great benefit in making resorbable biomedical cements. To optimize cements, additives are commonly us

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16

Gildenhaar, Renate, Georg Berger, E. Lehmann, and Christine Knabe. "Development of Alkali Containing Calcium Phosphate Cements." Key Engineering Materials 361-363 (November 2007): 331–34. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.331.

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Commercially available calcium phosphate cements set by precipitation of nanoapatite or brushite. The goal of this study was to elucidate the most suitable conditions for forming cements from calcium potassium sodium phosphate. Furthermore, the behaviour of these cements after immersion in SBF and/or TRIS solution was investigated. Using varying additives resulted in differences in solubility kinetics. The XRD spectra of all investigated cement compositions displayed Ca2KNa(PO4)2 after setting. However, the various cement compositions differed with respect to apatite formation when immersed in

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17

Hurle, K., J. M. Oliveira, R. L. Reis, S. Pina, and F. Goetz-Neunhoeffer. "Ion-doped Brushite Cements for Bone Regeneration." Acta Biomaterialia 123 (March 2021): 51–71. http://dx.doi.org/10.1016/j.actbio.2021.01.004.

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18

Charrière, E., S. Terrazzoni, C. Pittet, et al. "Mechanical characterization of brushite and hydroxyapatite cements." Biomaterials 22, no. 21 (2001): 2937–45. http://dx.doi.org/10.1016/s0142-9612(01)00041-2.

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19

Grover, Liam M., Michael P. Hofmann, Uwe Gbureck, Balamurgan Kumarasami, and Jake E. Barralet. "Frozen delivery of brushite calcium phosphate cements." Acta Biomaterialia 4, no. 6 (2008): 1916–23. http://dx.doi.org/10.1016/j.actbio.2008.06.003.

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20

Morilla, Claudia, Elianis Perdomo, Ana Karla Hernández, et al. "Effect of the Addition of Alginate and/or Tetracycline on Brushite Cement Properties." Molecules 26, no. 11 (2021): 3272. http://dx.doi.org/10.3390/molecules26113272.

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Calcium phosphate cements have the advantage that they can be prepared as a paste that sets in a few minutes and can be easily adapted to the shape of the bone defect, which facilitates its clinical application. In this research, six formulations of brushite (dicalcium phosphate dihydrated) cement were obtained and the effect of the addition of sodium alginate was analyzed, such as its capacity as a tetracycline release system. The samples that contain sodium alginate set in 4 or 5 min and showed a high percentage of injectability (93%). The cements exhibit compression resistance values betwee

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21

Vahabzadeh, Sahar, Mangal Roy, and Susmita Bose. "Effects of silicon on osteoclast cell mediated degradation, in vivo osteogenesis and vasculogenesis of brushite cement." Journal of Materials Chemistry B 3, no. 46 (2015): 8973–82. http://dx.doi.org/10.1039/c5tb01081k.

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22

Xia, W., M. R. Mohd Razi, P. Ashley, E. A. Abou Neel, M. P. Hofmann, and A. M. Young. "Quantifying effects of interactions between polyacrylic acid and chlorhexidine in dicalcium phosphate – forming cements." J. Mater. Chem. B 2, no. 12 (2014): 1673–80. http://dx.doi.org/10.1039/c3tb21533d.

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23

Navarro da Rocha, Daniel, Leila Rosa de Oliveira Cruz, Dindo Q. Mijares, et al. "Temperature Influence on the Calcium Phosphate Coatings by Chemical Method." Key Engineering Materials 720 (November 2016): 197–200. http://dx.doi.org/10.4028/www.scientific.net/kem.720.197.

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The increasing interest in the use of brushite and monetite as resorbable calcium phosphate cements or graft materials is related to the fact of these phases being metastable under physiological environment, with higher solubility than hydroxyapatite phase. In this study, X-ray diffraction (XRD) and scanning electron microscopy with field emission gun (FEG-SEM) analyses were performed in order to assess the temperature influence on the production of calcium phosphate coatings by a chemical deposition method. Titanium substrates were successfully coated with brushite and monetite by a chemical

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24

Moussa, Hanan, Amir El Hadad, Stylianos Sarrigiannidis, et al. "High toughness resorbable brushite-gypsum fiber-reinforced cements." Materials Science and Engineering: C 127 (August 2021): 112205. http://dx.doi.org/10.1016/j.msec.2021.112205.

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25

Hurle, K., F. R. Maia, V. P. Ribeiro, et al. "Osteogenic lithium-doped brushite cements for bone regeneration." Bioactive Materials 16 (October 2022): 403–17. http://dx.doi.org/10.1016/j.bioactmat.2021.12.025.

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26

Plokhikh, N. V., Ya Yu Filippov, V. I. Putlyaev, T. V. Safronova, and V. K. Ivanov. "Modifying brushite-containing phosphate cements by complexing additives." Russian Journal of Inorganic Chemistry 58, no. 10 (2013): 1152–59. http://dx.doi.org/10.1134/s0036023613100173.

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27

Lilley, K. J., U. Gbureck, A. J. Wright, J. C. Knowles, D. F. Farrar, and J. E. Barralet. "Brushite Cements from Polyphosphoric Acid, Calcium Phosphate Systems." Journal of the American Ceramic Society 90, no. 6 (2007): 1892–98. http://dx.doi.org/10.1111/j.1551-2916.2007.01619.x.

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28

Li, Guangda, Nan Zhang, Santuan Zhao, et al. "Fe-doped brushite bone cements with antibacterial property." Materials Letters 215 (March 2018): 27–30. http://dx.doi.org/10.1016/j.matlet.2017.12.054.

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29

Cama, G., F. Barberis, M. Capurro, L. Di Silvio, and S. Deb. "Tailoring brushite for in situ setting bone cements." Materials Chemistry and Physics 130, no. 3 (2011): 1139–45. http://dx.doi.org/10.1016/j.matchemphys.2011.08.047.

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30

Mestres, Gemma, Carlos F. Santos, Lars Engman, Cecilia Persson, and Marjam Karlsson Ott. "Scavenging effect of Trolox released from brushite cements." Acta Biomaterialia 11 (January 2015): 459–66. http://dx.doi.org/10.1016/j.actbio.2014.09.007.

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31

Cama, G., F. Barberis, R. Botter, et al. "Preparation and properties of macroporous brushite bone cements." Acta Biomaterialia 5, no. 6 (2009): 2161–68. http://dx.doi.org/10.1016/j.actbio.2009.02.012.

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32

Altundal, Sahin, Kārlis Agris Gross, Caroline Ohman, and Hakan Engqvist. "Improving the Flexural Strength Test of Brushite Cement." Key Engineering Materials 631 (November 2014): 67–72. http://dx.doi.org/10.4028/www.scientific.net/kem.631.67.

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In the investigation of mechanical properties, calcium phosphate cements exhibit large sample-to-sample deviation due to its porous nature, possibility of unhomogenous distribution and small specimen size. This situation generates difficulties for obtaining accurate results and creates an obstacle for testing different composition where only a small batch size is available. In this respect, specimen shape, whether being injected, porosity ratio, surface quality, bearing support design have significant matter on variability in terms of three-and four-point bending test. Therefore, different met

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33

Torres, P. M. C., A. Marote, A. R. Cerqueira, et al. "Injectable MnSr-doped brushite bone cements with improved biological performance." Journal of Materials Chemistry B 5, no. 15 (2017): 2775–87. http://dx.doi.org/10.1039/c6tb03119f.

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Combining Mn and Sr co-doping β-TCP powder with sucrose addition in the setting liquid enhances injectability, mechanical and biological performance of brushite-forming cements, renders them promising for minimally invasive surgery applications.

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34

Çetin, Ali Emrah, D. Şimşek, M. Çiftçioğlu, Yelda Akdeniz, Filiz Özmıhçı, and Arzu Aykut Yetkiner. "Investigation of HA Cement Preparation and Properties by Using Central Composite Design." Key Engineering Materials 493-494 (October 2011): 381–86. http://dx.doi.org/10.4028/www.scientific.net/kem.493-494.381.

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The goal of the present work was to investigate the effects of several cement preparation parameters on setting and hardening reaction mechanisms and hydroxyapatite (HA) cement properties. A central composite experimental design (CCD) was conducted by choosing particle size, solid to liquid ratio, pH, seed concentration and buffer concentration as design parameters along with compressive strength and setting time being the responses. Tetracalcium phosphate (TTCP) powders were prepared by heat treatment of calcium and phosphate source mixtures in the 1200-1400°C temperature range followed by qu

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35

Uskoković, Vuk, and Julietta V. Rau. "Nonlinear oscillatory dynamics of the hardening of calcium phosphate bone cements." RSC Advances 7, no. 64 (2017): 40517–32. http://dx.doi.org/10.1039/c7ra07395j.

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Nonlinear, oscillatory dynamics was discovered in the evolution of phase composition during the setting of different calcium phosphate cements, two of which evolved toward brushite and one toward hydroxyapatite as the final product.

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36

Khashaba, Rania M., Mervet Moussa, Christopher Koch, et al. "Preparation, Physical-Chemical Characterization, and Cytocompatibility of Polymeric Calcium Phosphate Cements." International Journal of Biomaterials 2011 (2011): 1–13. http://dx.doi.org/10.1155/2011/467641.

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Aim. Physicochemical mechanical andin vitrobiological properties of novel formulations of polymeric calcium phosphate cements (CPCs) were investigated.Methods. Monocalcium phosphate, calcium oxide, and synthetic hydroxyapatite were combined with either modified polyacrylic acid, light activated polyalkenoic acid, or polymethyl vinyl ether maleic acid to obtain Types I, II, and III CPCs. Setting time, compressive and diametral strength of CPCs was compared with zinc polycarboxylate cement (control). Specimens were characterized using X-ray diffraction, scanning electron microscopy, and infrared

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37

Steinacker, Valentin C., Tobias Renner, Ib Holzmeister, et al. "Biological and Mechanical Performance of Dual-Setting Brushite–Silica Gel Cements." Journal of Functional Biomaterials 15, no. 4 (2024): 108. http://dx.doi.org/10.3390/jfb15040108.

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Bone defects resulting from trauma, diseases, or surgical procedures pose significant challenges in the field of oral and maxillofacial surgery. The development of effective bone substitute materials that promote bone healing and regeneration is crucial for successful clinical outcomes. Calcium phosphate cements (CPCs) have emerged as promising candidates for bone replacement due to their biocompatibility, bioactivity, and ability to integrate with host tissues. However, there is a continuous demand for further improvements in the mechanical properties, biodegradability, and bioactivity of the

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38

Grover, Liam M., Uwe Gbureck, David Farrar, and J. E. Barralet. "Adhesion of a Novel Calcium Phosphate Cement to Cortical Bone and Several Common Biomaterials." Key Engineering Materials 309-311 (May 2006): 849–52. http://dx.doi.org/10.4028/www.scientific.net/kem.309-311.849.

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In this study, we have shown that by incorporating pyrophosphoric acid into a brushite cement system, it is possible to produce a cement that exhibits adhesive tensile strengths with cortical bone, alumina, sintered hydroxyapatite and 316L stainless steel of 700 kPa. To our knowledge, this is the first report of a calcium phosphate cement formulation that exhibits such adhesive properties without the addition of an organic additive. The production of a bond between medical prostheses and bone may further widen the field of application of calcium phosphate cements, additionally the adhesive nat

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39

Bohner, Marc. "pH Variations of a Solution after Injecting Brushite Cements." Key Engineering Materials 192-195 (September 2000): 813–16. http://dx.doi.org/10.4028/www.scientific.net/kem.192-195.813.

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40

Young, Anne M., Poon Yun J. Ng, Uwe Gbureck, Showan N. Nazhat, Jake E. Barralet, and Michael P. Hofmann. "Characterization of chlorhexidine-releasing, fast-setting, brushite bone cements." Acta Biomaterialia 4, no. 4 (2008): 1081–88. http://dx.doi.org/10.1016/j.actbio.2007.12.009.

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41

de Oliveira Renó, Caroline, Nicholas C. Pereta, Celso A. Bertran, Mariana Motisuke, and Eliandra de Sousa. "Study of in vitro degradation of brushite cements scaffolds." Journal of Materials Science: Materials in Medicine 25, no. 10 (2014): 2297–303. http://dx.doi.org/10.1007/s10856-014-5269-2.

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42

Pittet, C., and J. Lema�tre. "Mechanical characterization of brushite cements: A Mohr circles' approach." Journal of Biomedical Materials Research 53, no. 6 (2000): 769–80. http://dx.doi.org/10.1002/1097-4636(2000)53:6<769::aid-jbm19>3.0.co;2-p.

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43

Flautre, B., C. Maynou, J. Lemaitre, P. Van Landuyt, and P. Hardouin. "Bone colonization of ?-TCP granules incorporated in brushite cements." Journal of Biomedical Materials Research 63, no. 4 (2002): 413–17. http://dx.doi.org/10.1002/jbm.10262.

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44

Kim, Ji Hwan, Doug Youn Lee, and Sang Bae Lee. "Novel Antibacterial Calcium Phosphate Cement." Key Engineering Materials 330-332 (February 2007): 791–94. http://dx.doi.org/10.4028/www.scientific.net/kem.330-332.791.

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The antibacterial brushite-forming calcium phospahte cements (CPC) were prepared using an equimolar mixture of β-tricalcium phosphate (β-TCP) and monocalcium phosphate monohydrate (MCPM) with chlorine dioxide (ClO2) generating powders (sodium chlorite and mixed acid activator). The effect of ClO2 on cement setting time, compressive strength, and antibacterial property of novel antibacterial CPC was investigated. The use of 0.3M citric acid solutions as liquid phase enabled final setting times of 5~10 min. The setting time of antibacterial cement systems was prolonged with increasing the amount

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45

Loukopoulou, C., J. Vorstius, and J. Paxton. "COMPARISON OF BONE ANCHOR MATERIALS IN AN ANATOMICALLY RELEVANT IN VITRO MODEL OF THE BONE-TENDON INTERFACE." Orthopaedic Proceedings 105-B, SUPP_7 (2023): 83. http://dx.doi.org/10.1302/1358-992x.2023.7.083.

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To ensure clinical relevance, the in vitro engineering of tissues for implantation requires artificial replacements to possess properties similar to native anatomy. Our overarching study is focussed on developing a bespoke bone-tendon in vitro model replicating the anatomy at the flexor digitorum profundus (FDP) tendon insertion site at the distal phalanx. Anatomical morphometric analysis has guided FDP tendon model design consisting of hard and soft tissue types. Here, we investigate potential materials for creation of the model's bone portion by comparison of two bone cements; brushite and g

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46

Fleck, Sarah, and Sahar Vahabzadeh. "Magnesium-Substituted Brushite Cement: Physical and Mechanical Properties." Crystals 14, no. 3 (2024): 222. http://dx.doi.org/10.3390/cryst14030222.

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Brushite cements (BrCs) are calcium phosphate-based materials that are being widely used in hard tissue engineering applications due to their osteoconductivity, injectability, and bioresorbability. Therefore, the goal was to evaluate the effects of Mg concentration on the phase composition, setting time, and strength of BrC. Mg, which plays a vital role in bodily functions and bone health, was added to BrC at concentrations of 0.25, 0.50, 1.00, 1.50, 2.00, and 2.50 wt.%. The results showed that Mg stabilizes the TCP structure and increases the TCP content in final BrC. The initial and final se

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Silva, L. P., M. D. P. Ribeiro, E. S. Trichês, and M. Motisuke. "Brushite cement containing gelatin: evaluation of mechanical strength and in vitro degradation." Cerâmica 65, no. 374 (2019): 261–66. http://dx.doi.org/10.1590/0366-69132019653742585.

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Abstract Calcium phosphate cements (CPCs) are potential materials for repairing bone defects, mainly due to their excellent biocompatibility and osteoconductivity. Nevertheless, their low mechanical properties limit their usage in clinical applications. The gelatin addition may improve the mechanical and biological properties of CPCs, but their solubility in water may increase the porosity of the cement during degradation. Thus, the aim of this work was to investigate the influence of gelatin on the setting time, compressive strength and degradation rate of a brushite cement. CPCs were prepare

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Kim, Hyun Woo, Kyung Nahn Park та Kyung Sik Oh. "Injection Behavior of Brushite Bone Cement Prepared with Granulated β-Tricalcium Phosphate". Key Engineering Materials 758 (листопад 2017): 47–51. http://dx.doi.org/10.4028/www.scientific.net/kem.758.47.

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The injection behavior of β-tricalcium phosphate (Ca3(PO4)2: β-TCP) based cement was improved through the granulation of β-TCP. Dense β-TCP granules were obtained by heat treatment after spray drying. The fraction of injected paste under loaded mass in the syringe was measured while varying the granular fraction of β-TCP and the heat treatment temperature. The increase in granular fraction and heating treatment temperature reduced the amount of setting agent required to wet the granules. As the surplus setting agent could be used in the powdery β-TCP to reduce the viscosity, improved injectabi

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Cabrejos-Azama, Jatsue, Mohammad Hamdan Alkhraisat, Carmen Rueda, Jesús Torres, Luis Blanco, and Enrique López-Cabarcos. "Magnesium substitution in brushite cements for enhanced bone tissue regeneration." Materials Science and Engineering: C 43 (October 2014): 403–10. http://dx.doi.org/10.1016/j.msec.2014.06.036.

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Tamimi, Faleh, Jesus Torres, Enrique Lopez-Cabarcos, et al. "Minimally invasive maxillofacial vertical bone augmentation using brushite based cements." Biomaterials 30, no. 2 (2009): 208–16. http://dx.doi.org/10.1016/j.biomaterials.2008.09.032.

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