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Journal articles on the topic 'Buclizine'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

P, Mahajan Moreshwar, and Kashid Arun M. "HPTLC Method for the Estimation of Buclizine Hydrochloride (BUC) From Pure and Tablet Dosage Form." Der Pharma Chemica 14, no. 7 (2022): 7. https://doi.org/10.4172/0975-413X.14.7.49-55.

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A simple, selective, accurate, and precise High-Performance Thin-Layer chromatographic (HPTLC) method has been developed and validated for analysis of the Buclizine Hydrochloride (BUC) in bulk drug and pharmaceutical formulations. HPTLC was performed on aluminium sheets precoated with silica gel G 60F254 as a stationary phase. The mobile phase chosen for development consists of chloroform: ethyl acetate in the ratio of 8:2 (v/v). Buclizine Hydrochloride (BUC) showed good linear regression analysis over the concentration ranges 100-600 ng per spot with correlation coefficients (R2 ) = 0.999. Th

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2

Kuminek, Gislaine, Hellen K. Stulzer, Monika P. Tagliari, et al. "High-Performance Column Liquid Chromatographic Method for the Simultaneous Determination of Buclizine, Tryptophan, Pyridoxine, and Cyanocobalamin in Tablets and Oral Suspension." Journal of AOAC INTERNATIONAL 94, no. 6 (2011): 1785–90. http://dx.doi.org/10.5740/jaoacint.10-207.

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Abstract An HPLC method was developed and validated for the simultaneous determination of buclizine, tryptophan, pyridoxine, and cyanocobalamin in pharmaceutical formulations. The chromatographic separation was carried out on an RP-C18 column using a mobile phase gradient of methanol, 0.015 M phosphate buffer (pH 3.0), and 0.03 M phosphoric acid at a flow rate of 1.0 mL/min and UV detection at 230, 280, and 360 nm, respectively, for buclizine, tryptophan, pyridoxine, and cyanocobalamin. The method validation yielded good results with respect to linearity (r &gt; 0.999), specificity, precis

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3

Chaurasia, Rakesh, and Sandhya Chandra. "Buclizine- old wine in new bottle." International Journal of Basic & Clinical Pharmacology 1, no. 1 (2012): 122. http://dx.doi.org/10.5455/2319-2003.ijbcp001712.

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4

El Walily, Abdel Fattah M., Alaa El Gindy, and Abdel Aziz M. Wahbi. "A Spectrophotometric Method for the Determination of Buclizine Hydrochloride Using the Charge-Transfer Spectrum of Buclizine-Iodine Complex." Spectroscopy Letters 29, no. 2 (1996): 217–30. http://dx.doi.org/10.1080/00387019608001598.

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5

Wathore, Sandeep Ashokrao. "Formulation and In-Vitro Evaluation of Buclizine Buccoadhesive Tablets." Journal of Drug Delivery and Therapeutics 9, no. 4-A (2019): 137–44. http://dx.doi.org/10.22270/jddt.v9i4-a.3430.

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Buclizine is an antihistamine that is used to treat motions sickness, especially to prevent and treat symptoms such as abdominal pain, dizziness, nausea, vomiting, headaches, etc. It may also be used either alone or in a combination with other medicines for the treatment of hay fever and other allergic conditions. These dosages form make close contact with buccal mucosa, avoid first- pass metabolism, increase absorption and patient compliance, results in an enhanced drug bioavailability. Buccal adhesive tablets were prepared by direct compression. Carbopol 940 and Sodium Alginate was used in d

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6

Annapurna, V., G. Jyothi, A. V. Subbayamma, and B. B. V. Sailaja. "Spectrphotometric Determination of Buclizine as Hydrochloride Using Various Chromogenic Reagents." E-Journal of Chemistry 7, no. 4 (2010): 1523–29. http://dx.doi.org/10.1155/2010/350754.

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Simple, accurate and reproducible UV spectrophotometric methods were established for the assay ofbuclizine(BUCZ) based on the formation of precipitation, charge transfer complex and inner complex formation. Method A involves the precipitation, charge transfer complex formation of BUCZ with tannic acid/p-N-methyl aminophenol sulphate (PMAP)-Cr(VI), the complex formation with cobalt thiocyanate (CTC) in method B and inner complex formation of BUCZ with sodium nitroprusside hydroxylamine hydrochloride and sodium carbonate in method C were proposed. The optical characteristics such as Beers law li

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7

Adam, E. I. "A Treatment for the Acute Migraine Attack." Journal of International Medical Research 15, no. 2 (1987): 71–75. http://dx.doi.org/10.1177/030006058701500202.

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A compound analgesic/anti-emetic formulation was significantly effective in reducing the severity of acute attacks of migraine, in a double-blind, randomized, crossover trial of 34 patients referred to a migraine clinic. The preparation contained paracetamol (acetaminophen) 500 mg, codeine phosphate 8 mg, buclizine hydrochloride 6.25 mg and dioctyl sodium sulphosuccinate 10 mg. The dosage was two tablets taken as early as possible in the acute attack. No specific factors could be identified which influenced response to treatment Patients with a long history of migraine (more than 10 years) res

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8

Babu, ThirunavukkarasuArun. "Buclizine is back again! This time as a pediatric appetite stimulant." Indian Journal of Pharmacology 43, no. 2 (2011): 219. http://dx.doi.org/10.4103/0253-7613.77383.

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9

NANE, İkbal Demet, and Ebru ÇUBUK DEMİRALAY. "Thermodynamic protonation constant values of meclizine and buclizine in acetonitrile-water binary mixtures." Journal of Research in Pharmacy 25, no. 1 (2021): 1. http://dx.doi.org/10.35333/jrp.2021.290.

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10

NANE, İkbal Demet, and Ebru ÇUBUK DEMİRALAY. "Thermodynamic protonation constant values of meclizine and buclizine in acetonitrile-water binary mixtures." Journal of Research in Pharmacy 25, no. 1 (2021): 1. http://dx.doi.org/10.35333/jrp.2021.290.

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11

., Juber Pathan, Vishal Patil ., Abhijit Jadhav ., Manoj Nitalikar ., and Shrinivas Mohite . "Formulation and Evaluation of Mouth Dissolving Tablets of Buclizine HCl by Direct Compression Technique." Journal of Current Pharma Research 4, no. 2 (2014): 1168–71. http://dx.doi.org/10.33786/jcpr.2014.v04i02.009.

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12

Borukhova, Svetlana, Timothy Noël, and Volker Hessel. "Continuous-Flow Multistep Synthesis of Cinnarizine, Cyclizine, and a Buclizine Derivative from Bulk Alcohols." ChemSusChem 9, no. 1 (2015): 67–74. http://dx.doi.org/10.1002/cssc.201501367.

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13

Ramòn R, Riveliño, Jagger Segura, Byron Herrera, and Favian Bayas-Morejòn. "Effects of different levels of Buclizine hydrochloride for pigs during the growth and fattening phase." Online Journal of Animal and Feed Research 11, no. 4 (2021): 138–44. http://dx.doi.org/10.51227/ojafr.2021.21.

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14

Zakeri, Mina, Majid Monajjemi, and Ali Ebrahimi. "Thermodynamic investigation of promethazine, loratadine, cetirizine and buclizine as antihistamine drugs; monte carlo and semi-empirical studies." Nexo Revista Científica 33, no. 01 (2020): 94–108. http://dx.doi.org/10.5377/nexo.v33i01.10050.

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In this article, we discussed about four antihistamine drug called promethazine, loratadine, cetirizine and buclizine. Promethazine in this list is the only one in first generation antihistamine classification with CNS sedation effect and the other three belongs to second generation antihistamine group which are non-sedation and used to treat in many different anti-allergenic fields. In the following we optimized potential, kinetic and total energy of these molecules at body temperature (310 k˚) and environment temperature (298 k ˚) using Mont Carlo method in Amber force field in 500 ns. The q

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15

Wahbi, A.-A., A.-F. El-Walily, and A. El-Gindy. "High performance liquid chromatographic determination of buclizine dihydrochloride in the presence of acid-induced degradation products." Journal of Pharmacy and Pharmacology 50, S9 (1998): 119. http://dx.doi.org/10.1111/j.2042-7158.1998.tb02319.x.

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16

Arayne, Muhammad S., Najma Sultana, and Farhan A. Siddiqui. "Simultaneous Determination of Pyridoxine, Meclizine and Buclizine in Dosage Formulations and Human Serum by RP-LC." Chromatographia 67, no. 11-12 (2008): 941–45. http://dx.doi.org/10.1365/s10337-008-0615-5.

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17

Bitencourt, Monalisa, Olimpia Maria Martins Santos Viana, Andre Luiz Machado Viana, Jennifer Tavares Jacon Freitas, Cristiane Cabral de Melo, and Antonio Carlos Doriguetto. "Buclizine crystal forms: First Structural Determinations, counter-ion stoichiometry, hydration, and physicochemical properties of pharmaceutical relevance." International Journal of Pharmaceutics 589 (November 2020): 119840. http://dx.doi.org/10.1016/j.ijpharm.2020.119840.

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18

Siddiqui, Farhan Ahmed, Agha Zeeshan Mirza, M. Hashim Zuberi, and Faiza Qureshi. "Optimization of quantitative analysis of buclizine hydrochloride using UV spectrophotometry in bulk drug and dosage formulations." Medicinal Chemistry Research 20, no. 1 (2010): 121–24. http://dx.doi.org/10.1007/s00044-009-9286-5.

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19

Arayne, M. S., N. Sultana, M. Agha Zeeshan, and F. A. Siddiqui. "Simultaneous Determination of Gliquidone, Fexofenadine, Buclizine, and Levocetirizine in Dosage Formulation and Human Serum by RP-HPLC." Journal of Chromatographic Science 48, no. 5 (2010): 382–85. http://dx.doi.org/10.1093/chromsci/48.5.382.

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20

V., Annapurna, Jyothi G., Nagalakshmi V., and B. V. Sailaja B. "Spectrophotometric determination of Buclizine as hydrochloride (BUCZ) using I2/PMAP-SAc, AM/PTC and PMA/cobalt(II)/EDTA." Journal of Indian Chemical Society Vol. 86, Apr 2009 (2009): 358–63. https://doi.org/10.5281/zenodo.5809957.

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Department of Chemistry, St. Theresa's College for Women, Eluru-534 003, Andhra Pradesh, India Department of Inorganic & Analytical Chemistry, Andhra University, Visakhapatnam-530 003, Andhra Pradesh, India <em>E-mail</em> : sailaja_bbv@yahoo.co.in <em>Manuscript received 14 July 2008, accepted 24 December 2008</em> Simple, accurate and reproducible UV spectrophotometric methods were established for the assay of BUCZ based on the formation of precipitation, charge transfer and redox products. Precipitation/charge transfer complex formation of the BUCZ with I<sub>2</sub>/<em>p</em>-<em>

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21

Zanfirescu, Anca, Georgiana Nitulescu, Dragos Paul Mihai, and George Mihai Nitulescu. "Identifying FAAH Inhibitors as New Therapeutic Options for the Treatment of Chronic Pain through Drug Repurposing." Pharmaceuticals 15, no. 1 (2021): 38. http://dx.doi.org/10.3390/ph15010038.

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Chronic pain determines a substantial burden on individuals, employers, healthcare systems, and society. Most of the affected patients report dissatisfaction with currently available treatments. There are only a few and poor therapeutic options—some therapeutic agents are an outgrowth of drugs targeting acute pain, while others have several serious side effects. One of the primary degradative enzymes for endocannabinoids, fatty acid amide hydrolase (FAAH) attracted attention as a significant molecular target for developing new therapies for neuropsychiatric and neurological diseases, including

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22

Burgess, H. A., D. M. Merrington, W. J. Oliver, A. Thomson, and H. J. Rogers. "The relative bioavailability of paracetamol after rectal administration of suppositories containing a mixture of paracetamol, codeine phosphate and buclizine hydrochloride in healthy volunteers." Current Medical Research and Opinion 9, no. 9 (1985): 634–41. http://dx.doi.org/10.1185/03007998509109645.

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23

Sher, Nawab, Farhan Ahmed Siddiqui, Najmul Hasan, Nighat Shafi, Arif Zubair, and Agha Zeeshan Mirza. "Simultaneous determination of antihistamine anti-allergic drugs, cetirizine, domperidone, chlorphenamine maleate, loratadine, meclizine and buclizine in pharmaceutical formulations, human serum and pharmacokinetics application." Analytical Methods 6, no. 8 (2014): 2704. http://dx.doi.org/10.1039/c3ay41698d.

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24

Kuminek, Gislaine, Hellen K. Stulzer, Monika P. Tagliari, et al. "Development and validation of a stability-indicating HPLC method for the determination of buclizine hydrochloride in tablets and oral suspension and its application to dissolution studies." Química Nova 35, no. 1 (2012): 207–12. http://dx.doi.org/10.1590/s0100-40422012000100036.

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25

Persaud, Nirmala, E. Stewart Johnson, David Merrington, and William Oliver. "The relative bioavailability of paracetamol and codeine after oral administration of a combination of buclizine, paracetamol and codeine, with or without docusate, and of paracetamol alone in healthy volunteers." Current Medical Research and Opinion 9, no. 9 (1985): 626–33. http://dx.doi.org/10.1185/03007998509109644.

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26

Nane, İkbal Demet, Ebru Çubuk Demiralay, and Yaşar Doğan Daldal. "Comparison of Classical and Green RPLC Methods in the Determination of pKa Values of Some Piperazine Group Antihistamines." Chemistry – A European Journal, April 17, 2024. http://dx.doi.org/10.1002/chem.202400649.

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In this study, protonation constant values and liquid chromatographic behaviors of hydrophobic cyclizine, chlorcyclizine, hydroxyzine, cinnarizine, cetirizine, meclizine, and buclizine in some water‐organic solvent binary mixtures were examined for the first time using classical and green reverse phase liquid chromatography methods. In the isocratic study, the relationship of the retention time and mobile phase pH in water‐organic solvent binary mixtures containing acetonitrile (45, 50, 55, 60, 65, v/v), methanol (60, 65, 70, 75, v/v) and ethanol (45, 50, 55, 56, 59, 60, 62, 65, v/v) were dete

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