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1

Watanabe, Konosuke, Hiroyuki Shimada, Aman Sharma, et al. "(Invited) Investigation of Co-Free Cathode Composited with Proton Conductors for Protonic Ceramic Fuel Cells with Yb-Doped BaZrO3 Electrolyte." ECS Meeting Abstracts MA2024-02, no. 48 (2024): 3323. https://doi.org/10.1149/ma2024-02483323mtgabs.

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Protonic ceramic fuel cells (PCFCs) are expected to gain significant advantage from the use of Co-free cathodes. This shift can lead to reduced manufacturing costs and enhance durability performance. In our previous study, the investigation compared the power generation characteristics of PCFCs with BaZr0.8Yb0.2O3-δ (BZYb) electrolytes utilizing cathodes composed of La0.6Sr0.4FeO3-δ (LSF) as a Co-free cathode material and La0.6Sr0.4CoO3-δ (LSC) or La0.6Sr0.4Co0.2Fe0.8O3-δ (LSCF) as Co-containing cathode materials composited with BZYb. Consequently, the PCFC with an LSF-BZYb cathode exhibited l
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2

Yamauchi, Kosuke, Yuichi Mikami, and Tomohiro Kuroha. "Experimental Demonstration of the Electric Efficiency with BZYb based Protonic Ceramic Fuel Cell." ECS Transactions 111, no. 6 (2023): 1723–27. http://dx.doi.org/10.1149/11106.1723ecst.

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Protonic Ceramic Fuel Cell (PCFC) is expected to be the next-generation fuel cell due to its higher energy conversion efficiency. We evaluated the electric efficiency using a Φ60mm anode supported BZYb cell and a newly designed jig. The Φ60mm BZYb cell performed almost as well as the Φ20mm cell, and the maximum power reached 7 W at 12.9 A at 600ºC. In addition, we obtained the cell performance of 0.3 A cm–2 current density under various Uf (fuel utilization) condition. We demonstrated that a BZYb based PCFC could be operated at a high Uf condition (i.e., Uf = 90%), and the maximum electric eff
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3

Yamauchi, Kosuke, Yuichi Mikami, Tomohiro Kuroha, and Yuji Okuyama. "Experimental Study of the Electric Efficiency and Current Leakage with Bzyb Based Protonic Ceramic Fuel Cell." ECS Meeting Abstracts MA2024-02, no. 48 (2024): 3337. https://doi.org/10.1149/ma2024-02483337mtgabs.

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Protonic Ceramic Fuel Cell (PCFC) is expected to be the next-generation fuel cell for its higher energy conversion efficiency and lower operating temperature. BaZrO3 based oxide are potential materials as PCFC electrolyte because they have high chemical stability under the CO2 conditions and high proton conductivity. In the NEDO of Japan project started from FY2020, we have developed to demonstrate operation at high fuel utilization and to improve durability. In the previous report, we evaluated the electric efficiency using a Φ60mm anode supported PCFC and investigated the effect of the fuel
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4

Yamauchi, Kosuke, Yuichi Mikami, and Tomohiro Kuroha. "Experimental Demonstration of the Electric Efficiency with BZYb based Protonic Ceramic Fuel Cell." ECS Meeting Abstracts MA2023-01, no. 54 (2023): 266. http://dx.doi.org/10.1149/ma2023-0154266mtgabs.

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Protonic Ceramic Fuel Cell (PCFC) is expected to be the next-generation fuel cell for its higher energy conversion efficiency and lower operation temperature. BaZrO3 based oxide are potential materials as PCFC electrolyte because they have a high chemical stability under CO2 condition and high proton conductivity. We have developed PCFC using BaZr0.8Yb0.2Ox (BZYb) as the electrolyte and performed max power density 0.49 W cm–2 at 873 K. For practical use of PCFC, it is needed to conduct the higher electric efficiency and to improve the durability. Especially, improving the electric efficiency o
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5

Solodovnikov, Igor A., and Miklós Szekeres. "Three new species of Clausiliidae (Gastropoda, Pulmonata) from Abkhazia." Ruthenica, Russian Malacological Journal 27, no. 4 (2017): 159–65. http://dx.doi.org/10.35885/10.35885/ruthenica.2017.27(4).3.

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Acrotoma ( Castelliana ) likharevi sp. nov., Acrotoma ( Castelliana ) reshaviensis sp. nov., and Micropontica ( Baleopsina ) olgae sp. nov. are described from the Bzyb Mountains of Abkhazia. The taxonomic position, relation to congeneric taxa, and zoogeographical significance of the new taxa are discussed.
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6

Watanabe, Konosuke, Hiroyuki Shimada, Yuki Yamaguchi та ін. "Investigation of La0.65Ca0.35FeO3−δ as a Co-Free Cathode for Protonic Ceramic Fuel Cells with Yb-Doped BaZrO3 Electrolyte". ECS Meeting Abstracts MA2023-01, № 54 (2023): 50. http://dx.doi.org/10.1149/ma2023-015450mtgabs.

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In protonic ceramic fuel cells (PCFCs), the use of cobalt-free cathodes is expected to reduce manufacturing costs and improve durability performance. However, cobalt-free cathodes generally tend to have poor power generation performance due to their lower catalytic activity than cobalt-containing cathodes. Therefore, based on a previous study in which higher power generation performance was obtained with SOFCs using La0.65Ca0.35FeO3−δ (LCaF) than with SOFCs using La0.6Sr0.4Co0.2Fe0.8O3-δ (LSCF) containing cobalt, we focused on LCaF as a cobalt-free cathode. In this study, we attempted to apply
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7

Mikami, Yuichi, Kosuke Yamauchi, Tomohiro Kuroha, et al. "Durability and Interfacial Elemental Diffusion about BZYb based Protonic Ceramic Fuel Cell." ECS Meeting Abstracts MA2023-01, no. 54 (2023): 267. http://dx.doi.org/10.1149/ma2023-0154267mtgabs.

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Protonic ceramic fuel cells (PCFCs) are expected to be a highly efficient next-generation fuel cell because the fuel is not diluted by the generated water vapor during power generation. In the past research, we have found that Yb-doped BaZrO3 (BZYb) is promising in terms of the durability against CO2, proton conductivity, and less reactivity with NiO used for the fuel electrode. We are currently developing improvement of power generation efficiency and durability of PCFCs using BZYb electrolyte. In terms of the durability of PCFCs, there is concern about degradation due to diffusion of transit
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8

Makarov, Yuri N., Konstantin V. Taran, and Manushak N. Plyakic. "Defense of the Passes of the Bzyb Range (August – September 1942)." Общество: философия, история, культура, no. 12 (December 20, 2023): 191–98. http://dx.doi.org/10.24158/fik.2023.12.26.

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The article is devoted to the confrontation between the Soviet and German troops on the passes of the Bzyb Range in August – September 1942. As is known, by this time the Wehrmacht forces had suffered serious de-feats from the Soviet armed forces near Moscow, Rostov, and Tikhvin. The confrontation took a protracted character, so, planning the summer campaign of 1942, the German command decided to seize the most im-portant economic areas in the south of the USSR. The battle for the Caucasus included both the capture of the region’s passes and access to the Black Sea. It was precisely such fight
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9

Mikami, Yuichi, Kosuke Yamauchi, Tomohiro Kuroha, et al. "Durability and Interfacial Elemental Diffusion about BZYb based Protonic Ceramic Fuel Cell." ECS Transactions 111, no. 6 (2023): 1729–35. http://dx.doi.org/10.1149/11106.1729ecst.

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The durability of protonic ceramic fuel cells (PCFC) using Yb-doped BaZrO3 (BZYb) as electrolyte was investigated by 1000 h power generation tests and EPMA analysis of Co from cathode and Ni from anode. In addition, the effect of buffer layer of BaCeZrYYbO3-δ (BCZYYb) between the cathode and the electrolyte on durability and elemental diffusion was also investigated. In the cell with the buffer layer, the degradation of polarization resistance was suppressed in 1000 h power generation test. From EPMA analysis, Ni and Co segregation was observed in the electrolyte and the cathode after 1000 h p
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10

Sharma, Aman, Konosuke Watanabe, Hiroyuki Shimada, et al. "Enhanced PCFC performance via anode additive BaCO3–Induced grain growth in BZYb electrolyte." Journal of Power Sources 631 (March 2025): 236198. https://doi.org/10.1016/j.jpowsour.2025.236198.

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11

Mingazova, N. M., R. S. Dbar, V. M. Ivanova, et al. "Conditions of estuarine rivers of the Abkhazia Republic and their impact on the Black Sea coast." Marine Biological Journal 1, no. 4 (2016): 30–39. http://dx.doi.org/10.21072/mbj.2016.01.4.04.

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Estuaries play an important role in formation of coastal water quality and the conservation of biological diversity. In 2013–2014 the study of estuarine rivers in Abkhazia Black Sea region and their possible impacts was supported by RFBR grant. A number of large (Bzyb, Kodor, Gumista Kelasur, Galizga) and medium (Aapsta, Hypsta, Basle and others.) Abkhazia rivers have a significant impact on the ecological state of the Black Sea coast because of the runoff of sediments. We have studied a total of 35 rivers flowing into the Black Sea on the coast of Abkhazia and identified hydrological characte
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12

Nagata, Yohei, Takuto Araki, Kunpeng Li, et al. "Effect of Water Vapor and Hydrogen Concentration on Power Generation Characteristics of Protonic Ceramic Fuel Cell." ECS Meeting Abstracts MA2023-01, no. 54 (2023): 209. http://dx.doi.org/10.1149/ma2023-0154209mtgabs.

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The proton and hole conductivities of BaZrO3-based perovskites depend on partial pressures of oxygen and water vapor. These conductivities affect the power generation characteristics of Proton Ceramic Fuel Cells (PCFCs) using the perovskite as an electrolyte. In this study, the effect of humidification conditions on the power generation characteristics of an anode-supported PCFCs was investigated. The configuration of the anode-supported PCFC was La0.6Sr0.4Co0.2Fe0.8O3-δ (LSCF) cathode/BaZr0.8Yb0.2O3-δ(BZYb) electrolyte/Ni-BZYb anode. The diameter of the effective cathode area was approx. 10 m
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13

VARGOVITSH, ROBERT S. "Arrhopalites colchicus sp. nov. (Collembola: Symphypleona: Arrhopalitidae), the third highly troglomorphic species of the genus from the Caucasus." Zootaxa 5632, no. 1 (2025): 145–58. https://doi.org/10.11646/zootaxa.5632.1.8.

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The third highly troglomorphic Caucasian species of the genus Arrhopalites Börner, 1906 is described from Verkhneesherskaya Cave (Upper Eshera Cave) in the Gumishkha Massif, Abkhazia. Along with the two previously described Caucasian species, A. macronyx Vargovitsh, 2012 and A. profundus Vargovitsh, 2022, it belongs to the neustonic-hygropetric life form with a set of specific morphological adaptations: remarkably elongated claws, an enlarged sense organ on the third antennal segment, lamellate edges of the mucro, a well-developed mucronal anterior lamella, thin head and dens setae, and elonga
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14

Osadchiev, Alexander, Roman Sedakov, Alexandra Gordey, and Alexandra Barymova. "Internal Waves as a Source of Concentric Rings within Small River Plumes." Remote Sensing 13, no. 21 (2021): 4275. http://dx.doi.org/10.3390/rs13214275.

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This study is focused on concentric rings, which are regularly observed by remote sensing of small river plumes located in different regions worldwide. We report new aerial observations of these features obtained by quadcopters and supported by synchronous in situ measurements, which were collected during the recent field survey at the Bzyb river plume in the eastern part of the Black Sea. Joint analysis of remote sensing imagery and in situ data suggest that the observed concentric rings are surface manifestations of high-frequency internal waves generated in the vicinity of the river mouth.
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15

Kang, Ju Yun, Guang Yao Chen, Bao Tong Li, Zi Wei Qin, Xiong Gang Lu та Chong He Li. "Preparation of High Density BaZr0.97Y0.03O3-δ Ceramic and its Interaction with Titanium Melt". Key Engineering Materials 768 (квітень 2018): 261–66. http://dx.doi.org/10.4028/www.scientific.net/kem.768.261.

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In this paper, the BaZrO3(BZ) and BaZr0.97Y0.03O3-δ(BZY3) powders were prepared by using the industrial grade BaCO3, ZrO2and Y2O3powders combining the conventional solid state reaction. The BaZrO3(BZ) and BaZr0.97Y0.03O3-δ(BZY3) ceramics were fabricated at 1750°C. The effect of ball milling time and sintering aid (TiO2) on the sinterability of BaZr0.97Y0.03O3-δ(BZY3) ceramics were investigated, and the improved stability of BaZrO3refractory with Y2O3additive were studied according to the refractory-metal interaction. The results revealed that the particle size of BZY3 powders decreased first a
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16

Chervyatsova, O. Ya, S. S. Potapov, L. V. Leonova, J. Baker, and R. S. Dbar. "Mineral sediments of the Kholodnyy grotto cave(Bzyb Gorge, Abkhazia) and d13C carbon and d18O oxygenisotope composition of karstogenic carbonates." Vestnik of Geosciences 10 (2020): 12–21. http://dx.doi.org/10.19110/geov.2020.10.2.

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The article is devoted to the results of the study of the mineral and isotopic composition of speleothems of the of the Kholodnyy Grotto cavein the Bzyb gorge of Abkhazia. The cavity was mapped and various types of secondary mineral deposits were recorded. The following mineral formations (speleothems) have been established in the cave: Mondmilch, corallites, guhrs, carbonate breccias, biogenic phosphates. Attention is drawn to the abundance of allogeneic mineral inclusions in drip calcite associated with the weathering products of igneous rocks (zircon, potassium feldspar, ilmenite, rutile, m
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17

Zelnitskaya, R. Sh. "The sanctuary of Dydrypsh-nykha yesterday and today." Kunstkamera 19, no. 1 (2023): 112–20. http://dx.doi.org/10.31250/2618-8619-2023-1(19)-112-120.

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The sanctuary of Dydrypsh, which is located on the territory of the Achandara village in Bzyb region of Abkhazia, is revered by all Abkhazian society. According to local residents, not only the sanctuary is the main one, but also its priest, who currently conducts rituals during public prayers. The article highlights three key topics related to this sacred place. Primarily these are pre-revolutionary sources and the information about the sanctuary contained in them, as well as scientific literature on this topic. Special attention is paid to the priests from the Chichba clan, who were first me
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18

Belousov, I. A., and A. G. Koval. "Taniatrechus xeniae sp. nov. (Coleoptera: Carabidae: Trechini), the second species of the most specialised troglobitic carabid genus of the Caucasus." Zoosystematica Rossica 32, no. 2 (2023): 163–89. http://dx.doi.org/10.31610/zsr/2023.32.2.163.

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Taniatrechus xeniae sp. nov., the second species of the genus, is described from Prostornaya Cave in the central part of the Bzyb Mountain Range, Abkhazia. A comparative study of all available specimens of the genus is carried out using both linear morphometrics (indices) and geometric morphometrics: generalised Procrustes analysis (GPA), principal component analysis (PCA), and canonical variate analysis (CVA). This study allowed us to estimate infraspecific variation in the external morphology of T. setosus Belousov et Dolzhansky, 1994, on the one hand, and to reveal reliable diagnostic featu
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19

Hu, Huijia, Jie Zou, Liang Shan, et al. "Conductivities in Yttrium-Doped Barium Zirconate: A First-Principles Study." Crystals 13, no. 3 (2023): 401. http://dx.doi.org/10.3390/cryst13030401.

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Yttrium-doped barium zirconate (BZY) has emerged as an attractive candidate for application as a proton (H+)-conducting solid electrolyte due to its high ionic conductivity and excellent chemical stability. In this study, the conductivities of BaZr(1−x)YxO3−δ (BZY, x = 0, 0.037, 0.074, 0.148, and 0.22) with different carriers were studied based on density functional theory (DFT) and experiments. The results revealed that yttrium doping can effectively reduce the energy barrier for the migration of protons and oxygen ions (O2−). When comparing the energy barriers for protons and oxygen ions, th
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20

Erlikh, Vladimir R., Anna S. Leotyeva, and Alexandra N. Abramova. "NEW PROTOMEOTIAN BURIAL GROUND IN THE FOOTHILLS OF ADYGEA." History, Archeology and Ethnography of the Caucasus 20, no. 2 (2024): 489–509. https://doi.org/10.32653/ch202489-509.

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This article presents materials from a newly discovered burial ground of the Protomeotian group of sites, located in the foothills of Adygea on the Azishsky Ridge near the village of Dakhovskaya. The burial ground was discovered by the team of the Caucasian Expedition LLC “Kulturnoye Nasledie” in 2023 (chief of the expedition – A.S. Leontieva) during the study of the mound “Azishsky-16,” the main burial of which dates to the Early Bronze Age. The Protomeotian burial ground was found overlaying this mound. The site contains nine burials with Proto-Meotian material, situated on a rocky base unde
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21

Belousov, Igor A., and Alexander G. Koval. "Taniatrechus xeniae sp. nov. (Coleoptera: Carabidae: Trechini), the second species of the most specialised troglobitic carabid genus of the Caucasus." Zoosystematica Rossica 32, no. 2 (2023): 163–89. https://doi.org/10.31610/zsr/2023.32.2.163.

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<em>Taniatrechus xeniae</em>&nbsp;<strong>sp. nov.</strong>, the second species of the genus, is described from Prostornaya Cave in the central part of the Bzyb Mountain Range, Abkhazia. A comparative study of all available specimens of the genus is carried out using both linear morphometrics (indices) and geometric morphometrics: generalised Procrustes analysis (GPA), principal component analysis (PCA), and canonical variate analysis (CVA). This study allowed us to estimate infraspecific variation in the external morphology of&nbsp;<em>T. setosus</em>&nbsp;Belousov et Dolzhansky, 1994, on the
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22

Trebeleva, Galina, and Suram Sakania. "The spread of christianity in Abkhazia according to the spatial analysis of monuments in GIS in the late antique and medieval periods." InterCarto. InterGIS 30, no. 1 (2024): 352–83. https://doi.org/10.35595/2414-9179-2024-1-30-352-383.

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The article is devoted to the analysis of the spatial location of temples in Abkhazia and reconstruction based on the results of the ways of penetration and spread of Christianity in different chronological stages: the period of late antiquity and the first penetration of Christianity into the territory of Colchis (IV–V centuries); the period of maximum Byzantine influence in the era of Justinian the Great and the period that following it (VI–VII centuries)—the period traditionally considered the stages of the official adoption of Christianity in Abkhazia; and the period of the maximum flouris
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23

Kang, Xiuhong, Mengdi Jia, Luqing Zhao та Shengsheng Zhang. "Bu-Zhong-Yi-Qi Granule Enhances Colonic Tight Junction Integrity via TLR4/NF-κB/MLCK Signaling Pathway in Ulcerative Colitis Rats". Evidence-Based Complementary and Alternative Medicine 2021 (9 березня 2021): 1–12. http://dx.doi.org/10.1155/2021/6657141.

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Background. Bu-zhong-yi-qi granule (BZYQ), a sort of Chinese herbal medicine, has exhibited therapeutic effects on ulcerative colitis (UC). However, the mechanism of BZYQ has not been fully clarified. This study was aimed at investigating the effects of BZYQ on UC rats model and at exploring its potential mechanism. Methods. The UC rats were established by enema of trinitrobenzene sulfonic acid (TNBS). The therapeutic effects of BZYQ treatment were evaluated by disease activity index (DAI), colon macroscopic damage index (CMDI) scores, and histological observation. The mRNA levels of tumor nec
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24

Kushare, Mayuri Madhukar, Sandrine Ricote та Greg Jackson. "Assessing the Impact of BaZr0.7Y0.3-YPryO3- d Composition on Water Splitting Kinetics in Composite Pr2NiO4+Δ-BaZr0.7Y0.3-YPryO3- d Electrodes in Proton-Conducting Electrolysis Cells". ECS Meeting Abstracts MA2023-01, № 54 (2023): 340. http://dx.doi.org/10.1149/ma2023-0154340mtgabs.

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Protonic-ceramic electrolysis cells (PCECs), with proton-conducting oxide electrolytes, provide high current densities between 500-700°C because electrolytes such as BaCe0.8-xZrxY0.1Yb0.1O3-δ (BCZYYb) have protonic conductivities in this temperature range. The protonic conductivities of BCZYYb are almost an order of magnitude higher than oxide-ion conductivities in conventional solid-oxide electrolytes. To convert such high ionic fluxes in PCECs into efficient hydrogen production, robust positive electrodes (positrodes) must be developed with reduced overpotentials associated with water-splitt
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25

Ni, Zhexin, Wen Cheng, Jie Ding, et al. "Impact of Buzhong Yiqi Prescription on the Gut Microbiota of Patients with Obesity Manifesting Polycystic Ovarian Syndrome." Evidence-Based Complementary and Alternative Medicine 2021 (March 15, 2021): 1–19. http://dx.doi.org/10.1155/2021/6671367.

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Gut microbiota disorders are closely related to polycystic ovarian syndrome (PCOS). Buzhong Yiqi prescription (BZYQ) has a significant clinical effect on the treatment of patients with obesity exhibiting PCOS and phlegm-dampness syndrome caused by spleen deficiency (SPSD). Hence, this study aimed to explore gut microbiota and fecal metabolite alterations in such patients treated with BZYQ. Fifty eligible patients with obesity manifesting PCOS and SPSD participated and agreed to undergo 3 months of BZYQ treatment. Results showed that BZYQ significantly alleviated the serum dehydroepiandrosteron
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26

Ahn, Damiro, Hyun-Jung Choi, Ho-dong Kim, and Sang Young Yeo. "Properties of Conductive Polyacrylonitrile Fibers Prepared by Using Benzoxazine Modified Carbon Black." Polymers 12, no. 1 (2020): 179. http://dx.doi.org/10.3390/polym12010179.

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Composites of carbon black (CB) and polymers are attractive for producing conductive fibers. Herein, to achieve improved interactions with polymers, the surface of CB was modified to form 4-aminobenzoyl-functionalized carbon black (ABCB), benzoxazine-functionalized carbon black (BZCB), and Ag-anchored carbon black (Ag-ABCB). The surface-modified CBs were characterized by Fourier transform infrared spectroscopy and thermogravimetric analysis, and X-ray photoelectron spectroscopy was utilized to confirm the presence of Ag in Ag-ABCB. Conductive polyacrylonitrile (PAN) fibers were wet-spun with c
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27

Schneller, Theodor, and David Griesche. "Inkjet Printed Y-Substituted Barium Zirconate Layers as Electrolyte Membrane for Thin Film Electrochemical Devices." Membranes 9, no. 10 (2019): 131. http://dx.doi.org/10.3390/membranes9100131.

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In this work, the inkjet printing of proton conducting Y-substituted barium zirconate (BZY) thin films was studied. Two different kinds of precursor inks, namely a rather molecular BZY precursor solution and a BZY nanoparticle dispersion, have been synthesized and initially investigated with regard to their decomposition and phase formation behavior by thermal analysis, X-ray diffraction, and scanning electron microscopy. Their wetting behavior and rheological properties have been determined in order to evaluate their fundamental suitability for the inkjet process. Crystalline films have been
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28

Еременко, Е. А., Р. Ю. Жиба, М. А. Кузнецов, and С. И. Болысов. "The Coastal Morphology of Gagra Bay and the Modern Trends of the Development of the Conditions of Sea Level Increase." Вестник Рязанского государственного университета имени С.А. Есенина, no. 2(75) (August 4, 2022): 149–63. http://dx.doi.org/10.37724/rsu.2022.75.2.015.

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Выполнена морфогенетическая типизация берегов Гагрского залива Черного моря. Установлено, что в пределах городской черты Гагры абсолютно преобладают техногенные берега, представляющие собой сочетание волнозащитных или волноотбойных стенок с пляжеудерживающими бунами, подводными и надводными волноломами и каменными набросками. По состоянию на 2022 год продольные берегозащитные сооружения в основном эффективно функционируют, однако местами частично разрушены морем. Поперечные сооружения (буны) по большей части разобраны, однако есть и полностью сохранившиеся, продолжающие выполнять пляжеудержива
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29

Ye, Shiqiao, Wei Qiang, Yu Chen, et al. "MAF Protein Elicits Innate Resistance To Bortezomib In Multiple Myeloma." Blood 122, no. 21 (2013): 281. http://dx.doi.org/10.1182/blood.v122.21.281.281.

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Abstract Multiple myeloma (MM) is a malignancy of terminally differentiated clonal plasma cells displaying significant molecular heterogeneity with 7 subgroups defined by gene expression profiling (GEP). Our previous work showed that MS and MF subgroups have been associated with inferior survival (Zhan et al, blood 2006). Furthermore, clinical studies have demonstrated that the addition of the proteasome inhibitor (PI) bortezomib (Bzb) to high dose melphalan based regimens provided a major advantage to patients in MS subgroup (Barlogie NJE 2006, Blood 2008; Pineda-Roman et al BJH 2008), while
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30

Qiang, Ya-Wei, Shiqiao Ye, Faith E. Davies, Bart Barlogie, Joshua Epstein, and Gareth J. Morgan. "Mafb Protein Confers Primary Resistance of Myeloma to Proteasome Inhibitors." Blood 124, no. 21 (2014): 2091. http://dx.doi.org/10.1182/blood.v124.21.2091.2091.

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Abstract Multiple myeloma (MM) is a malignancy of terminally differentiated clonal plasma cells displaying significant molecular heterogeneity with 7 subgroups defined by gene expression profiling (GEP). Our previous work showed that both the MS and MF subgroups associated with inferior survival (Zhan et al, Blood 2006). Furthermore, clinical studies have demonstrated that the addition of the proteasome inhibitor (PI) bortezomib (Bzb) to high dose melphalan based regimens provided a major advantage to patients in MS subgroup while patients in the MF subgroups (including C-MAF and MAFb) did not
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31

Yun, Dae, Jaegyeom Kim, Seung-Joo Kim, et al. "Structural and Electrochemical Properties of Dense Yttria-Doped Barium Zirconate Prepared by Solid-State Reactive Sintering." Energies 11, no. 11 (2018): 3083. http://dx.doi.org/10.3390/en11113083.

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For practical utilization of proton-conducting ceramic fuel cells and electrolyzers, it is essential to lower the sintering temperature and processing time of BaZrO3-based proton conductors. We investigated the effect of sintering temperature and time on the structural and electrochemical properties of dense BaZr0.8Y0.2O3−δ (BZY) prepared by a solid-state reactive sintering process, using NiO as a sintering aid. The sintered BZY prepared from the micronized precursor powder exhibited a density higher than 93%, and an average grain size in the range of 0.6 to 1.4 μm. The orthorhombic BaY2NiO5 p
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32

Hadi, Abdul-Sommed, Fiona Morrow, and John David Kirtley. "Examination of Morphological and Chemical Properties of Ni-BZY Anodes and their Influence upon Methane Reactivity and Electrochemical Performance of Protonic-Ceramic Fuel Cells." ECS Transactions 111, no. 6 (2023): 2171–87. http://dx.doi.org/10.1149/11106.2171ecst.

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Ni-BZY (yttrium-doped barium zirconate) has drawn recent interest for application in protonic ceramic fuel cells (PCFCs) due to BZY’s superior protonic conductivity and stability in reforming environments containing CO2 and H2O. Additionally, Ni and BZY form unique nano/microstructures thought to synergistically facilitate reforming. While PCFCs with Ni-BZY anodes have demonstrated stable long-term performance, little is known about the material’s transformations during operation and subsequent impact on electrochemical metrics. To address this knowledge gap, we constructed PCFCs consisting of
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33

Qiang, Ya-Wei, Bo Hu, Yu Chen та ін. "Bortezomib induces osteoblast differentiation via Wnt-independent activation of β-catenin/TCF signaling". Blood 113, № 18 (2009): 4319–30. http://dx.doi.org/10.1182/blood-2008-08-174300.

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Abstract Inhibition of Wnt/β-catenin/T-cell factor (TCF) signaling induces proliferation of mesenchymal stem cells and/or suppresses their differentiation into osteoblasts (OBs). Osteolysis in multiple myeloma (MM) is related to the suppression of canonical Wnt signaling caused by DKK1, a soluble inhibitor of this pathway secreted by MM cells. Bortezomib (Bzb) can induce OB differentiation in vitro and in vivo and its anti-MM efficacy linked to bone anabolic effects. However, the molecular basis of the action of Bzb on bone is not completely understood. In the present study, we show that Bzb p
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34

Hadi, Abdul-Sommed, Fiona Morrow, and John David Kirtley. "Examination of Morphological and Chemical Properties of Ni-BZY Anodes and their Influence upon Methane Reactivity and Electrochemical Performance of Protonic-Ceramic Fuel Cells." ECS Meeting Abstracts MA2023-01, no. 54 (2023): 339. http://dx.doi.org/10.1149/ma2023-0154339mtgabs.

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Protonic ceramic fuel cells (PCFCs) have recently emerged as potential alternatives to traditional solid oxide fuel cells due in part to their enhanced tolerance to performance losses caused by coking and sulfur poisoning. These advantages can be attributed to the unique cermet anode materials used in these devices. Ni-BZY (yttrium-doped barium zirconate) in particular has been widely investigated due to BZY’s superior protonic conductivity and stability in hydrocarbon reforming environments containing carbon dioxide and steam. In addition, Ni and BZY have been observed to form unique nano/mic
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35

Watanabe, Takashi, Masato Mitsuhashi, Morihiko Sagawa, et al. "Discovery of Unique Biomarkers That Predict Bortezomib-Induced Peripheral Neuropathy: The Results of a Multicenter Prospective Clinical Study of Multiple Myeloma in Japan." Blood 120, no. 21 (2012): 1816. http://dx.doi.org/10.1182/blood.v120.21.1816.1816.

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Abstract Abstract 1816 Introduction: The first-in-class proteasome inhibitor bortezomib (Bzb) has revolutionized the treatment of multiple myeloma (MM). However, Bzb often induces peripheral neuropathy (PN), which negatively affects clinical outcomes by necessitating the reduction or discontinuation Bzb treatment. If patients who are likely develop Bzb-induced PN (BiPN) could be predicted, physicians might have an additional opportunity to modify the dose regimen or reduce the Bzb dose in Bzb-based combination regimens, administer Bzb subcutaneously, or use different drugs. Methods: We conduct
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36

Zhou, Ping, and Raymond L. Comenzo. "Proteasome Activity Not M-Protein Production Influences Multiple Myeloma (MM) Responsiveness to Bortezomib (BZB): The Key Role of PSMB5,." Blood 118, no. 21 (2011): 3491. http://dx.doi.org/10.1182/blood.v118.21.3491.3491.

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Abstract Abstract 3491 M-protein load may sensitize MM cells to BZB but models thus far have not directly tested that hypothesis, in one case using a subclone of an IgGκ-producing human MM cell line differing 5X from the parent line with respect to intracellular M-protein concentration (Ca Res 2007;67:1783), and in another using MM cell lines differing in proteasome activity (Blood 2009;113:3040). In other models proteasome activity has been increased by exposure to low doses of bortezomib or by over-expression of PSMB5, the gene for the β5c subunit, reducing sensitivity to BZB (Blood 2008;112
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37

Onishi, Takayuki, Donglin Han, Yohei Noda, Naoyuki Hatada, Masatoshi Majima, and Tetsuya Uda. "Evaluation of performance and durability of Ni-BZY cermet electrodes with BZY electrolyte." Solid State Ionics 317 (April 2018): 127–35. http://dx.doi.org/10.1016/j.ssi.2018.01.015.

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38

Kang, Shimeng, Penghui Yao, Zehua Pan, et al. "High-Temperature Mechanical–Conductive Behaviors of Proton-Conducting Ceramic Electrolytes in Solid Oxide Fuel Cells." Materials 17, no. 19 (2024): 4689. http://dx.doi.org/10.3390/ma17194689.

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Proton-conducting solid oxide fuel cells (P-SOFCs) are widely studied for their lower working temperatures than oxygen-ion-conducting SOFCs (O-SOFCs). Due to the elevated preparation and operation temperatures varying from 500 °C to 1500 °C, high mechanical stresses can be developed in the electrolytes of SOFCs. The stresses will in turn impact the electrical conductivities, which is often omitted in current studies. In this work, the mechanical–conductive behaviors of Y-doped BaZrO3 (BZY) electrolytes for P-SOFCs under high temperatures are studied through molecular dynamics modeling. The You
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39

Taiswa, Amos, Zachary Noctor, Abdul-Sommed Hadi, Jessica M. Andriolo, Jack L. Skinner, and John David Kirtley. "Synthesis and Characterization of Electrospun Ni-BZY Nano-Fiber Anodes." ECS Meeting Abstracts MA2024-01, no. 47 (2024): 2620. http://dx.doi.org/10.1149/ma2024-01472620mtgabs.

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Solid oxide fuel cell (SOFC) and related Protonic Ceramic Fuel Cell (PCFC) technologies have demonstrated significant promise for the efficient and clean electrochemical conversion of stored energy held in a wide variety of renewable fuels, decreasing dependence on traditional fossil fuels. The high efficiencies of both devices arise from the direct chemical-to-electrical energy transformation, achieved without moving parts and the losses inherent to combustion technologies. As in all fuel cells, electrons are generated via oxidation of fuel at the anode to power an external load before return
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40

Taillades, Gilles, Ismahan Hachemi, Paul Pers, Julian Dailly, and Mathieu Marrony. "Synthesis and Characterizations of Barium Zirconate–Alkali Carbonate Composite Electrolytes for Intermediate Temperature Fuel Cells." Journal of Composites Science 5, no. 7 (2021): 183. http://dx.doi.org/10.3390/jcs5070183.

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Composite ionic conductors for intermediate temperature fuel cells (ITFC) were produced by a combination of yttrium-substituted barium zirconate (BaZr0.9Y0.1 O2.95, BZY) and eutectic compositions of alkali carbonates (Li2CO3, Na2CO3, and K2CO3, abbreviated L, N, K). These materials were characterized by X-ray diffraction, scanning electron microscopy, and impedance spectroscopy. The combination of BZY with alkali metal carbonate promotes the densification and enhances the ionic conductivity, which reaches 87 mS·cm−1 at 400 °C for the BZY–LNK40 composite. In addition, the increase of the conduc
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41

Osman, Nafisah, Nurul Waheeda Mazlan, Oskar Hasdinor Hassan, Wan Zuliana Wan Zulkifli, and Zakiah Mohamed. "Phase Analysis of Cerate and Zirconate Ceramics Powder Prepared by Supercritical Ethanol Using High Temperature-High Pressure Batch Wise Reactor System." Solid State Phenomena 307 (July 2020): 171–75. http://dx.doi.org/10.4028/www.scientific.net/ssp.307.171.

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OAbstract. One of the approaches that has been done to produce a better performance of an intermediate temperature solid oxide fuel cell (IT-SOFC) is by varying the synthesis methods. This paper focused on the proton conducting electrolyte in particularly barium cerate and barium zirconate system namely BaCe0.9Y0.1O3-δ (BCY) and BaZr0.9Y0.1O3-δ (BZY). Supercritical ethanol processing technique is one of the alternative synthesis routes that able to produce ceramics powder at lower calcination temperature. The samples were synthesized in High-Pressure-High-Temperature (HP-HT) Batch Wise reactor
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42

Xiao, Jin, Hongchun Yuan, Lei Chen та ін. "Anode-supported BaZr0.8Y0.2O3−δ membranes by tape casting and suspension spraying". International Journal of Modern Physics B 31, № 16-19 (2017): 1744062. http://dx.doi.org/10.1142/s0217979217440623.

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Dense BaZr[Formula: see text]Y[Formula: see text]O[Formula: see text] (BZY) proton-conducting electrolyte membranes are successfully fabricated on NiO–BaZr[Formula: see text]Ce[Formula: see text]Y[Formula: see text]O[Formula: see text](NiO–BZCY) using tape casting combined with suspension spraying technique. The NiO–BZCY anode substrates were prepared by the tape-casting method and the BZY electrolyte membranes were prepared on the NiO-BZCY anodes by suspension spraying. The thermal decomposition of the anode green tape prepared by tape casting was investigated by thermogravimetry-differential
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43

Watanabe, Takashi, Masato Mitsuhashi, Morihiko Sagawa, et al. "A Biomarker Obtained From Whole Peripheral Blood Predicts Response to Bortezomib: Results of a Multicenter Prospective Clinical Study of Multiple Myeloma in Japan." Blood 120, no. 21 (2012): 2954. http://dx.doi.org/10.1182/blood.v120.21.2954.2954.

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Abstract Abstract 2954 Introduction: The first-in-class proteasome inhibitor bortezomib (Bzb) has revolutionized the treatment of multiple myeloma (MM). However, identifying a biomarker to predict which patients will respond to Bzb is a priority in selecting this treatment or determining whether this powerful but toxic armament should be continued in individual patients. Furthermore, to monitor the efficacy of Bzb, peripheral blood (PB) biomarkers are more desirable than painful bone marrow aspirations. Methods: We conducted a multicenter prospective study to seek biomarkers that predict a res
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44

Lescure, Victoire, Mélanie François, Maëlys Charleux, et al. "Reactive Magnetron Sputtering for Y-Doped Barium Zirconate Electrolyte Deposition in a Complete Protonic Ceramic Fuel Cell." Crystals 14, no. 5 (2024): 475. http://dx.doi.org/10.3390/cryst14050475.

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Yttrium-doped barium zirconate is a commonly used electrolyte material for Protonic Ceramic Fuel Cells (PCFC) due to its high protonic conductivity and high chemical stability. However, it is also known for its poor sinterability and poor grain boundary conductivity. In this work, in response to these issues, reactive magnetron sputtering was strategically chosen as the electrolyte deposition technique. This method allows the creation of a 4 µm tick electrolyte with a dense columnar microstructure. Notably, this technique is not widely utilized in PCFC fabrication. In this study, a complete ce
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Fujii, Takeo, Kazuaki Toyoura, Tetsuya Uda, and Shusuke Kasamatsu. "Theoretical study on proton diffusivity in Y-doped BaZrO3 with realistic dopant configurations." Physical Chemistry Chemical Physics 23, no. 10 (2021): 5908–18. http://dx.doi.org/10.1039/d0cp06035f.

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46

Edmunds, Laurel D., Kirsten L. Rennie, Stuart King, and Helen Mayhew. "Experiences of those Taking Part in the BeeZee Bodies Family- Based Weight Management Intervention: A Qualitative Evaluation." International Journal of Child Health and Nutrition 3, no. 4 (2014): 163–69. https://doi.org/10.6000/1929-4247.2014.03.04.2.

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The need for effective community, child weight management interventions continues. The BeeZee Bodies (BZB) family-based child weight management programme for 7-11-year-olds and 12-15&ndash;year-olds has been developed iteratively over five years, with quantitative and qualitative evaluations refining the programmes. The aim of this study was to present the experiences and opinions of those taking part in BZB programmes as part of a real world evaluation. Three focus groups, following a semi-structured protocol, were conducted with 20 participants (15 parents, 5 adolescents) 3 months post-inter
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47

Shin, Hyun Ho, Junil Choi, Taiho Park, and Won Bae Kim. "Anodic Reaction in Syngas-Fueled Proton-Conducting Solid Oxide Fuel Cells." International Journal of Energy Research 2023 (February 3, 2023): 1–11. http://dx.doi.org/10.1155/2023/9844833.

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Anode-supported proton-conducting solid oxide fuel cells (PC-SOFCs) fabricated with two representative proton-conducting oxides, BaCe0.7Zr0.1Y0.1Yb0.1O3-δ (BCZYYb) and BaZr0.8Y0.2O3-δ (BZY), were compared to obtain the insight into the electrochemical performances when fueled with syngas at 700°C and the correlation between the anode thickness (0.4, 0.8, and 1.6 mm) and operational stability. We have demonstrated that, in stability tests, the BCZYYb cells exhibited significantly higher maximum power density (MPD) than the BZY cells when operating on H2, 1.22 and 0.48 W/cm2 for the BCZYYb and B
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48

Ding, Hanping, Shuanglin Zheng, Saroj Karki, and Allison Le. "Manufacturing of Proton Conducting Solid-Oxide Electrolysis Cells Based on Yttrium‐Doped Barium Zirconate Electrolyte." ECS Meeting Abstracts MA2024-02, no. 50 (2024): 4862. https://doi.org/10.1149/ma2024-02504862mtgabs.

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Proton-conducting solid oxide electrolysis cell (P-SOEC) has been recently recognized as a promising technology for delivering fast hydrogen production at lower temperature range to hold the promise of utilizing cheaper stack materials and reducing degradation. The current P-SOEC technology has been progressed into a new development stage with promising technical accomplishments. The operating temperatures have been effectively pushed down to 500~600°C to enable use of cheaper interconnects and to improve material system compatibility. However, the P-SOEC development is in its early stage due
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49

Jin, Xinfang, and Yasser Shoukry. "Current Leakage and Faradaic Efficiency Simulation of Proton-Conducting Solid Oxide Electrolysis Cells." ECS Meeting Abstracts MA2023-01, no. 54 (2023): 179. http://dx.doi.org/10.1149/ma2023-0154179mtgabs.

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Proton conducting solid oxide electrolysis cells (H-SOEC) have advantages over its oxygen-ion-conducting (O-SOEC) counterpart due to lower operating temperature (e.g. 300-700oC), relatively lower activation energy, and easier gas separation [1, 2]. However, it suffers from low Faradaic efficiency led by the internal current leakage. Protonic ceramics like BaZr0.90Y0.10O3 (BZY) are generally mixed proton, oxygen ion and electron hole conducting oxides, in which the transference number of each charge carrier depends on the material composition, operating temperature, atmosphere, and polarization
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Jin, Xinfang, and Yasser Shoukry. "Current Leakage and Faradaic Efficiency Simulation of Proton-Conducting Solid Oxide Electrolysis Cells." ECS Transactions 111, no. 6 (2023): 1159–67. http://dx.doi.org/10.1149/11106.1159ecst.

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In this study, we simulated BZY electrolyte-supported proton-conducting solid oxide cell by coupling surface defect chemistry reaction with charged species transport. We validated the model parameters by concentration as a function of temperature, conductivity under dry and wet oxygen as a function of oxygen partial pressure and temperature. The results indicate that the high electron-hole mobility (diffusivity) is mainly responsible for the high leaking current under high temperatures. The Faradaic efficiency stays low or even negative under low operating voltage or high temperature and plate
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