Academic literature on the topic 'C.E.C.D. Mira Sintra'

OBJETIVO: avaliar o efeito do tamoxifeno no perfil lipídico e renal de ratos controles e diabéticos. MÉTODOS: Foram utilizados 40 ratos fêmeas Wistar (180-220g peso corporal), divididos randomicamente em 4 grupos: C (n=10, receberam veículo), T (n=10, tratados com tamoxifeno, 0,3mg/kg/dia), D (n=10, diabéticos induzidos por estreptozotocina, 45mg/Kg) e DT (n=10, diabéticos tratados com tamoxifeno). Foram dosados os analitos, glicose, colesterol total, triglicérides, proteínas totais, albumina, uréia e creatinina utilizando Kits Labtest através do analisador Cobas Mira (Alemanha,1996). RESULTADOS: o grupo T apresentou diminuição do colesterol total e triglicérides em relação ao C, e o grupo D um aumento em relação aos demais. Para as proteínas totais foi observado um aumento no Grupo T em relação ao C. A albumina diminuiu nos grupos D e DT em relação aos grupos C e T. Nos níveis de uréia houve um aumento no grupo D e DT em relação aos grupos C e T. CONCLUSÃO: Em relação ao perfil lipídico foi constatado que durante o período de 60 dias o tratamento com tamoxifeno promoveu uma diminuição dos níveis séricos de colesterol e triglicérides, mesmo associado a condição de Diabetes mellitus.

-Dennis Walder, Robert D. Hamner, Derek Walcott. New York: Twayne Publishers, 1993. xvi + 199 pp.''Critical perspectives on Derek Walcott. Washington DC: Three continents, 1993. xvii + 482 pp.-Yannick Tarrieu, Lilyan Kesteloot, Black writers in French: A literary history of Negritude. Translated by Ellen Conroy Kennedy. Washington DC: Howard University Press, 1991. xxxiii + 411 pp.-Renée Larrier, Carole Boyce Davies ,Out of the Kumbla: Caribbean women and literature. Trenton NJ: Africa World Press, 1990. xxiii + 399 pp., Elaine Savory Fido (eds)-Renée Larrier, Evelyn O'Callaghan, Woman version: Theoretical approaches to West Indian fiction by women. London: Macmillan Caribbean, 1993. viii + 126 pp.-Lisa Douglass, Carolyn Cooper, Noises in the blood: Orality, gender and the 'vulgar' body of Jamaican popular culture. London: Macmillan Caribbean, 1993. ix + 214 pp.-Christine G.T. Ho, Kumar Mahabir, East Indian women of Trinidad & Tobago: An annotated bibliography with photographs and ephemera. San Juan, Trinidad: Chakra, 1992. vii + 346 pp.-Eva Abraham, Richenel Ansano ,Mundu Yama Sinta Mira: Womanhood in Curacao. Eithel Martis (eds.). Curacao: Fundashon Publikashon, 1992. xii + 240 pp., Joceline Clemencia, Jeanette Cook (eds)-Louis Allaire, Corrine L. Hofman, In search of the native population of pre-Colombian Saba (400-1450 A.D.): Pottery styles and their interpretations. Part one. Amsterdam: Natuurwetenschappelijke Studiekring voor het Caraïbisch Gebied, 1993. xiv + 269 pp.-Frank L. Mills, Bonham C. Richardson, The Caribbean in the wider world, 1492-1992: A regional geography. Cambridge: Cambridge University Press, 1992. xvi + 235 pp.-Frank L. Mills, Thomas D. Boswell ,The Caribbean Islands: Endless geographical diversity. New Brunswick NJ: Rutgers University Press, 1992. viii + 240 pp., Dennis Conway (eds)-Alex van Stipriaan, H.W. van den Doel ,Nederland en de Nieuwe Wereld. Utrecht: Aula, 1992. 348 pp., P.C. Emmer, H.PH. Vogel (eds)-Idsa E. Alegría Ortega, Francine Jácome, Diversidad cultural y tensión regional: América Latina y el Caribe. Caracas: Nueva Sociedad, 1993. 143 pp.-Barbara L. Solow, Ira Berlin ,Cultivation and culture: Labor and the shaping of slave life in the Americas. Charlottesville: University Press of Virginia, 1993. viii + 388 pp., Philip D. Morgan (eds)-Andrew J. O'Shaughnessy, Karen Ordahl Kupperman, Providence Island, 1630-1641: The other puritan colony. Cambridge: Cambridge University Press, 1993. xiii + 393 pp.-Armando Lampe, Johannes Meier, Die Anfänge der Kirche auf den Karibischen Inseln: Die Geschichte der Bistümer Santo Domingo, Concepción de la Vega, San Juan de Puerto Rico und Santiago de Cuba von ihrer Entstehung (1511/22) bis zur Mitte des 17. Jahrhunderts. Immensee: Neue Zeitschrift für Missionswissenschaft, 1991. xxxiii + 313 pp.-Edward L. Cox, Carl C. Campbell, Cedulants and capitulants; The politics of the coloured opposition in the slave society of Trinidad, 1783-1838. Port of Spain, Trinidad: Paria Publishing, 1992. xv + 429 pp.-Thomas J. Spinner, Jr., Basdeo Mangru, Indenture and abolition: Sacrifice and survival on the Guyanese sugar plantations. Toronto: TSAR, 1993. xiii + 146 pp.-Rosemarijn Hoefte, Lila Gobardhan-Rambocus ,Immigratie en ontwikkeling: Emancipatie van contractanten. Paramaribo: Anton de Kom Universiteit, 1993. 262 pp., Maurits S. Hassankhan (eds)-Juan A. Giusti-Cordero, Teresita Martínez-Vergne, Capitalism in colonial Puerto Rico: Central San Vicente in the late nineteenth century. Gainesville: University Press of Florida, 1992. 189 pp.-Jean Pierre Sainton, Henriette Levillain, La Guadeloupe 1875 -1914: Les soubresauts d'une société pluriethnique ou les ambiguïtés de l'assimilation. Paris: Autrement, 1994. 241 pp.-Michèle Baj Strobel, Solange Contour, Fort de France au début du siècle. Paris: L'Harmattan, 1994. 224 pp.-Betty Wood, Robert J. Stewart, Religion and society in post-emancipation Jamaica. Knoxville: University of Tennessee Press, 1992. xx + 254 pp.-O. Nigel Bolland, Michael Havinden ,Colonialism and development: Britain and its tropical colonies, 1850-1960. New York: Routledge, 1993. xv + 420 pp., David Meredith (eds)-Luis Martínez-Fernández, Luis Navarro García, La independencia de Cuba. Madrid: MAPFRE, 1992. 413 pp.-Pedro A. Pequeño, Guillermo J. Grenier ,Miami now! : Immigration, ethnicity, and social change. Gainesville: University Press of Florida, 1992. 219 pp., Alex Stepick III (eds)-George Irving, Alistair Hennessy ,The fractured blockade: West European-Cuban relations during the revolution. London: Macmillan Caribbean, 1993. xv + 358 pp., George Lambie (eds)-George Irving, Donna Rich Kaplowitz, Cuba's ties to a changing world. Boulder CO: Lynne Rienner, 1993, xii + 263 pp.-G.B. Hagelberg, Scott B. MacDonald ,The politics of the Caribbean basin sugar trade. New York: Praeger, 1991. vii + 164 pp., Georges A. Fauriol (eds)-Bonham C. Richardson, Trevor W. Purcell, Banana Fallout: Class, color, and culture among West Indians in Costa Rica. Los Angeles: UCLA Center for Afro-American studies, 1993. xxi + 198 pp.-Gertrude Fraser, George Gmelch, Double Passage: The lives of Caribbean migrants abroad and back home. Ann Arbor: University of Michigan Press, 1992. viii + 335 pp.-Gertrude Fraser, John Western, A passage to England: Barbadian Londoners speak of home. Minneapolis: University of Minnesota Press, 1992. xxii + 309 pp.-Trevor W. Purcell, Harry G. Lefever, Turtle Bogue: Afro-Caribbean life and culture in a Costa Rican Village. Cranbury NJ: Susquehanna University Press, 1992. 249 pp.-Elizabeth Fortenberry, Virginia Heyer Young, Becoming West Indian: Culture, self, and nation in St. Vincent. Washington DC: Smithsonian Institution Press, 1993. x + 229 pp.-Horace Campbell, Dudley J. Thompson ,From Kingston to Kenya: The making of a Pan-Africanist lawyer. Dover MA: The Majority Press, 1993. xii + 144 pp., Margaret Cezair Thompson (eds)-Kumar Mahabir, Samaroo Siewah, The lotus and the dagger: The Capildeo speeches (1957-1994). Port of Spain: Chakra Publishing House, 1994. 811 pp.-Donald R. Hill, Forty years of steel: An annotated discography of steel band and Pan recordings, 1951-1991. Jeffrey Thomas (comp.). Westport CT: Greenwood, 1992. xxxii + 307 pp.-Jill A. Leonard, André Lucrèce, Société et modernité: Essai d'interprétation de la société martiniquaise. Case Pilote, Martinique: Editions de l'Autre Mer, 1994. 188 pp.-Dirk H. van der Elst, Ben Scholtens ,Gaama Duumi, Buta Gaama: Overlijden en opvolging van Aboikoni, grootopperhoofd van de Saramaka bosnegers. Stanley Dieko. Paramaribo: Afdeling Cultuurstudies/Minov; Amsterdam: Koninklijk Instituut voor de Tropen, 1992. 204 pp., Gloria Wekker, Lady van Putten (eds)-Rosemarijn Hoefte, Chandra van Binnendijk ,Sranan: Cultuur in Suriname. Amsterdam: Koninklijk Instituut voor de Tropen/Rotterdam: Museum voor Volkenkunde, 1992. 159 pp., Paul Faber (eds)-Harold Munneke, A.J.A. Quintus Bosz, Grepen uit de Surinaamse rechtshistorie. Paramaribo: Vaco, 1993. 176 pp.-Harold Munneke, Irvin Kanhai ,Strijd om grond in Suriname: Verkenning van het probleem van de grondenrechten van Indianen en Bosnegers. Paramaribo, 1993, 200 pp., Joyce Nelson (eds)-Ronald Donk, J. Hartog, De geschiedenis van twee landen: De Nederlandse Antillen en Aruba. Zaltbommel: Europese Bibliotheek, 1993. 183 pp.-Aart G. Broek, J.J. Oversteegen, In het schuim van grauwe wolken: Het leven van Cola Debrot tot 1948. Amsterdam: Muelenhoff, 1994. 556 pp.''Gemunt op wederkeer: Het leven van Cola Debrot vanaf 1948. Amsterdam: Muelenhoff, 1994. 397 pp.

Abstract Women trafficking is a kind of activity in which women are exploited. In women trafficking activity , there is no consideration of women’s right. The target is those women can be used to get money as much as possible. The women can become the victim of women trafficking is due to the ability of the panders in doing persuasion. Through various strategies, these panders are successful in pushing these women to fall into this inhuman activity. One of the strategy is by politely ensuring them. This writing is aimed at describing the politeness strategy used by panders in persuading women to be the victim of women trafficking. The research is conducted in West Java (Bekasi, Cirebon, and Indramayu). The data are any utterances of the panders in persuading the women to be the victim of women trafficking. Observational method with note-taking, recording, and interviewing is used to collect data. The analysis is done by pragmatic and referential identity method related to the concept of politeness proposed Brown and Levinson (1987), Oktavianus and Revita (2013), Leech (2014), and Mira (2010). The result of analysis is descriptively presented. Having analyzed data, it is found that there are four politeness strategies used by the panders in woman trafficking activities. They are ( (a) bald on record; (b) positive politeness; (c) negative politeness; and (d) off record.---AbstrakPerdagangan perempuan merupakan bentuk kegiatan ekploitasi perempuan. Di sini, perempuan dijadikan sebagai ajang komoditas. Tujuannya adalah utk menjadikan perempuan sebagai alat pencari uang sebanyak2nya. Perempuan sdh banyak yg jadi korban praktik perdagangan perempuan paracalo nakal. Mereka (Paracalo) ini berhasil menjerat para perempuan dg menggunakan berbagai strategi. Salah satu strateginya adalah dg cara meyakinkan/membujuk sikorban. Tulisan ini bertujuan utk memaparkan strategi paracalo dlm menjerat korbannya. Penelitian ini dilakukan di wilayah Jawa Barat (Bekasi, Cirebon, and Indramayu). Data penelitian ini diambil dari keterangan paracalo perdagangan perempuan. Pengumpulan data dilakukan melalui metode observasi dg mencatat, merekam, dan melakukan wawancara. Teknik analisi yg digunakan adlh analisis pragmatik dan metode identitas referensi yg relevan dg konsep “kesopanan” yg diusung olh Brown and Levinson (1987), Oktavianus and Revita (2013), Leech (2014), and Mira (2010). Data yg sdh terkumpul dianalisis secara deskriptif. Berdasarkan hasil analisis, penelitian ini menyimpulkan ada empat macam strategi kesopanan yg digunakan olh paracalo dlm mendekati mangsanya: (a) bald on record; (b) positive politeness; (c) negative politeness; and (d) off record. Kata kunci: strategi kesopanan, perdagangan perempuan, korban, calo, perempuan.DOI: 10.15408/al-turas.v23i1.4810

Laboratory and field-cage experiments evaluated the efficacy of a water-soluble bait for control of adult diabroticites. The bait was composed of a water-soluble feeding stimulant derived from a bitter mutant of Hawkesbury watermelon (Citrullus vulgaris Schrad), a dye toxin (phloxine B: D & C Red Dye No. 28), and a modified food starch (Mira Sperse 626). In the laboratory, southern corn rootworm, Diabrotica undecimpunctata howardi Barber adults, were exposed to separate bait components and combinations thereof. Eighty percent of adults exposed to the complete bait formulation died within 24 h. Adult mortality increased with higher concentrations of dye and increasing light intensity. Incorporation of the feeding stimulant with the dye reduced the lethal time. The complete bait was most active in sunlight, killing 90% adults in 1 h. Under fluorescent lights, the LT90 for the adults was 48 h. In field cages, using corn plants treated with the bait formulation, numbers of live western corn rootworm, D. virgifera virgifera LeConte, adults were reduced by 80% compared with the untreated control. This new water soluble toxic bait appears suitable for testing on a larger scale in the field as a component of an IPM program for corn rootworm pests.

Context. Variability is a key property of stars on the asymptotic giant branch (AGB). Their pulsation period is related to the luminosity and mass-loss rate of the star. Long-period variables (LPVs) and Mira variables are the most prominent of all types of variability of evolved stars. The reddest, most obscured AGB stars are too faint in the optical and have eluded large variability surveys. Aims. We obtained a sample of LPVs by analysing K-band light curves (LCs) of a large number of sources in the direction of the Magellanic Clouds with the colours expected for red AGB stars ((J − K) > 3 mag or equivalent in other colour combinations). Methods. Selection criteria were derived based on colour-colour and colour-magnitude diagrams from the combination of the VISTA Magellanic Cloud (VMC) survey, Spitzer IRAC and AllWISE data. After eliminating LPVs with known periods shorter than 450 days, a sample of 1299 candidate obscured AGB stars was selected. K-band LCs were constructed by combining the epoch photometry available in the VMC survey with literature data, were analysed for variability, and fitted with a single period sine curve to derive mean magnitudes, amplitudes, and periods. A subset of 254 stars are either new variables, known variables where the period we find is better determined than the literature value, or variables with periods longer than 1000 days. The spectral energy distributions (SEDs) of these stars were fitted to a large number of templates. For this purpose the SEDs and Spitzer IRS spectra of some non-AGB stars (Be stars, HII regions and young stellar objects – YSOs) were also fitted to have templates of the most likely contaminants in the sample. Results. A sample of 217 likely LPVs is found. Thirty-four stars have periods longer than 1000 days, although some of them have alternative shorter periods. The longest period of a known Mira in the Magellanic Clouds from Optical Gravitational Lensing Experiment data (with P = 1810 d) is derived to have a period of 2075 d based on its infrared LC. Two stars are found to have longer periods, but both have lower luminosities and smaller pulsation amplitudes than expected for Miras. Mass-loss rates and luminosities are estimated from the template fitting. Period-luminosity relations are presented for carbon (C-) and oxygen (O-) rich Miras that appear to be extensions of relations derived in the literature for shorter periods. The fit for the C stars is particularly well defined (with 182 objects) and reads Mbol = (−2.27 ± 0.20) ⋅ log P + (1.45 ± 0.54) mag with an rms of 0.41 mag. Thirty-four stars show pulsation properties typical of Miras while the SEDs indicate that they are not. Overall, the results of the LC fitting are presented for over 200 stars that are associated with YSOs.

<p><span>Este trabajo se propone dar cuenta, desde una persp</span><span>ectiva histórica, de cuáles fueron los estudios e </span><span>investigaciones que se han realizado en distintos c</span><span>ampos y desde diferentes enfoques, en los temas que</span><span> refieren a la </span><span>historia de vida y su posterior extensión al campo </span><span>de la formación como “historia de formación”. </span><span>Así, la tarea efectuada se limitó a la revisión e i</span><span>ndagación respecto de referencias al uso de la hist</span><span>oria de vida en las </span><span>ciencias sociales, en el campo de la historia, la a</span><span>ntropología y la sociología; para luego investigar </span><span>su aplicación en los </span><span>campos más específicos de formación de los docentes</span><span> y, posteriormente, de la formación de adultos en g</span><span>eneral. </span><span>En ese recorrido nos encontramos con distintas mira</span><span>das y posiciones. Por ello y a los fines de esta co</span><span>municación </span><span>presentaremos una selección, es decir, un recorte d</span><span>e aquellos antecedentes que nos han servido para mo</span><span>strar el camino </span><span>realizado. </span><span>El uso de las historias de vida en la docencia e i</span><span>nvestigación universitaria puede ser recuperado co</span><span>mo una herramienta </span><span>para la historización y reconocimiento de los proce</span><span>sos de formación de adultos y su ubicación en un c</span><span>ampo especifico </span><span>de estudio e interpretación. De esta manera, las hi</span><span>storias de vida devienen en historias de formación </span><span>que, al </span><span>especificarse, facilitan la comprensión que el suj</span><span>eto hace de sus propios procesos de formación, como</span><span> así también la </span><span>identificación en profundidad del campo de la form</span><span>ación para avanzar en su comprensión y en el desc</span><span>ubrimiento e </span><span>indagación de sus significados.</span></p><p> </p>

Representing over 25% of the vegetable production, Brassicaceae crops are very important for Portuguese agriculture. Xanthomonas campestris pv. raphani (Xcr) was first described as the causative agent of a leaf spot disease affecting radish and turnip (4). Despite its ability to infect Solanaceae hosts upon inoculation, this pathogen affects mostly Brassicaceae plants. Typical symptoms include circular dark spots that become lighter and are occasionally surrounded by a chlorotic halo. In severely affected leaves, spots were not limited by the veins and coalesced into irregular shapes that perforated the leaves, rendering the plants unsuitable for marketing. In the early 2000s, several isolates causing leaf spots on Brassica oleracea varieties (cauliflower, white cabbage, savoy cabbage, and tronchuda cabbage) were collected in Sintra, near Lisbon. The isolates, identified as putative X. campestris (Xc), formed typical yellow mucoid and convex colonies when grown on YDC medium. Biochemical characterization (2) showed their ability to produce levan and hydrolyze starch and esculin. Isolates were also able to use celobiose, trehalose, glucose, mannose, raffinose, and sucrose. Furthermore, the isolates were oxidase negative and were unable to hydrolyze arginine and to use rhamnose, indol, inositol, and sorbitol, confirming them as Xc. The expected 619-bp amplicon was obtained for all isolates, after PCR using primers DLH120/DLH125 (1). Koch's postulates were fulfilled through pathogenicity tests on B. oleracea cv. Wirosa and Raphanus sativus, hosts susceptible to Xcr as well as to X. campestris pv. campestris (Xcc). Inoculations on B. carinata (Assession No. PI199947) and Solanum lycopersicum, hosts susceptible only to Xcr, were performed to confirm pathovar identification (2). Four plants of each host were inoculated with each isolate by spraying bacterial water suspensions (OD600 = 0.1) onto leaf surfaces. Positive and negative controls were performed using Xcc type strain (CFBP 5241) and sterile distilled water, respectively. Plants were kept 15 days with 16-h light and 8-h dark photoperiods at 24 and 18°C, respectively, at RH >80% and checked daily for symptom development. Leaf spots typical of Xcr were observed for all isolates on all hosts 5 days after inoculation. All isolates were recovered after re-isolation from inoculated plants, retaining their initial features. Negative control plants showed no symptoms, while CFBP 5241 caused V-shaped lesions, typical of Xcc, on B. oleracea cv. Wirosa and R. sativus. Further confirmation of the identification was attained by partial sequencing of the gyrB gene, using primers X.gyr.fsp.s1/X.gyr.rsp3 (3). Sequences from four isolates (CPBF 143, Genbank KM094906; CPBF 207, GenBank KM094907; CPBF 209, GenBank GU596416; and CPBF 1171, GenBank GU596419) were compared by nucleotide blast at NCBI and displayed higher levels of DNA similarity (>98%) to NCPPB 1946, the type strain for Xcr, than to NCPPB 528, the type strain for Xcc. The polyphasic approach combining phenotypic and genomic data confirmed the presence of X. campestris pv. raphani in Portugal for the first time. References: (1) T. Berg et al. Plant Pathol. 54: 416, 2005. (2) R. Lelliot and D. Stead. Methods for the Diagnosis of Bacterial Diseases of Plants. Blackwell Scientific Publications, Oxford, England, 1987. (3) N. Parkinson et al. Int. J. Syst. Evol. Microbiol. 57:2881, 2007. (4) H. White. Phytopathology 20:653, 1930.

Методом центрифугирования сформированы пленки наноразмерного диапазона толщины (лазерная, спектральная эллипсометрия) системы Y2O3–Fe2O3 на монокристаллическом InP из нитратного раствора. Состав пленок, выращенных без отжига - YFe2O4; отожженных термически при 200 °С – YFe2O4, Fe2O3 с примесью Fe3O4; прошедших импульсную фотонную обработку (50 Дж/см2, 0.4 с) и термооксидирование (450–550 °С, время 10–60 мин) – YFe2O4 и YFeO3. Отжиг с последующим термооксидированием способствует уменьшению размера зерен на поверхности выращенной пленки, но увеличивает среднюю шероховатость. Импульсная фотонная обработка обусловливает повышенную неровность поверхности гетероструктуры. ИСТОЧНИК ФИНАНСИРОВАНИЯРабота выполнена при поддержке грантаРФФИ №18-03-00354 а. REFERENCES Zvezdin A. K., Logginov A. S., Meshkov G. A., Pyatakov A. P. Multiferroics: Promising materials for microelectronics, spintronics, and sensor technique. Bulletin of the Russian Academy of Sciences: Physics, 2007, v. 71(11), pp. 1561−1562. https://doi.org/10.3103/S1062873807110263 Fahlman B. Materials Chemistry. Springer Netherlands, 2011, 736 p. DOI: 10.1007/978-94-007-0693-4 Gubin S. P., Koksharov Yu. A., Khomutov G. B., Yurkov G. Yu. Magnetic nanoparticles: preparation, structure and properties. Russian Chemical Reviews, 2005, v. 74 (6), pp. 489–520. https://doi.org/10.1070/RC2005v074n06ABEH000897 Shabanova N. A., Popov V. V., Sarkisov P. D. Khimiya i tekhnologiya nanodispersnykh oksidov [Chemistry and technology of nanodispersed oxides]. M.: IKC Akademkniga Publ., 2007, 309 p. (in Russ.). Lima H. R. B. R., Nascimento D. S., Sussuchi E. M., Errico F. D., Souza S. O. Synthesis of MgB4O7 and Li2B4O7 crystals by proteic sol-gel and Pechini methods. Journal of Sol-gel Science and Technology, 2017, v. 81(3), pp. 797−805. https://doi.org/10.1007/s10971-016-4249-z Serrao C. R., Sahu J. R., Athinarayanan S., Rao C. N. R. Magnetoelectric effect in rare earth ferrites, LnFe2O4. Journal of Applied Physics, 2008, v. 104(1), p. 16102. https://doi.org/10.1063/1.2946455 Xu C., Yang Y., Wang S., Duan W., Gu B., Bellaiche L. Anomalous properties of hexagonal rare-earth ferrites from fi rst principles. Physical Review B, 2014, v. 89(20), p. 205122. https://doi.org/10.1103/Phys-RevB.89.205122 Mahalakshmi S., SrinivasaManja K., Nithiyanantham S. Electrical properties of nanophase ferrites doped with rare earth ions. Journal of Superconductivity and Novel Magnetism, 2014, v. 27(9), pp. 2083–2088. https://doi.org/10.1007/s10948-014-2551-y Sanchez-Andujar M., Mira J., Rivas J. Enhanced magnetoresistance in the ruddlesden−popper compound Sr3Fe1.5Co0.5O6.67. Journal of Magnetism and Magnetic Material, 2003, v. 263(3), pp. 282−288. https://doi.org/10.1016/S0304-8853(02)01576-7 Khomskii D. I. Multiferroics: Different ways to combine magnetism and ferroelectricity. Journal of Magnetism and Magnetic Material, 2006, v. 306(1), pp. 1−8. https://doi.org/10.1016/j.jmmm.2006.01.238 Patel R., Simon C., Weller M. LnSrScO4 (Ln = La, Ce, Pr, Nd and Sm) systems and structure correlations for A2BO4 (K2NiF4) structure types. Journal of Solid State Chemistry, 2007, v. 180, pp. 349−359. https://doi.org/10.1134/S0036023615100162 Popkov V. I., Almjasheva O. V., Schmidt M. P., Gusarov V. V. Formation mechanism of nanocrystalline yttrium orthoferrite under heat treatment of the coprecipitated hydroxides. Russian Journal of General Chemistry, 2015, v. 85(6), pp. 1370−1375. https://doi.org/10.1134/S0036023615100162 Popkov V. I., Izotova S. G., Almjasheva O. V., Schmidt M. P., Gusarov V. V. Features of nanosized YFeO3 formation under heat treatment of glycinenitrate combustion products. Russian Journal of Inorganic Chemistry, 2015, v. 60(10), pp. 1193−1198. https://doi.org/10.1134/S0036023615100162 Chithralekha P., Murugeswari C., Ramachandran K., Srinivasan R. The study on ultrasonic velocities of CoxFe3-xO4 nanoferrofl uid prepared by co-precipitation method. Nanosystems: Physics, Chemistry, Mathematics, 2016, v. 7(3), pp. 558–560. https://doi.org/10.17586/2220-8054-2016-7-3-558-560 Nguyen A. T., Phan Ph. Nh, Mittova I. Ya., Knurorova M. V., Mittova V. O. The characterization of nanosized ZnFe2O4 material prepared by coprecipitation. Nanosystems: Physics, Chemistry, Mathematics, 2016, v. 7(3), pp. 459–463. https://doi.org/10.17586/2220-8054-2016-7-3-459-463 Lomanova N. A., Ugolkov V. L., Gusarov V. V. Thermal behavior of layered perovskite-like compounds in the Bi4Ti3O12-BiFeO3 system. Glass Physics and Chemistry, 2007, v. 33(6), pp. 608−612. https://doi.org/10.1134/S1087659607060120 Nguyen A. T., Almjasheva O. V., Mittova I. Ya., Stognei O. V., Soldatenko S. A. Synthesis and magnetic properties of YFeO3 nanocrystals. Inorganic Materials, 2009, v. 45(11), pp. 1392–1397. https://doi.org/10.1134/S002016850 Perrot P. Iron–Oxygen–Yttrium. Ternary Alloy Systems, 2009, v. 11(5), pp. 1–18. https://doi.org/10.1007/978-3-540-70890-2_23 Shiwani Sharma, Saravanan P., Pandey O. P, Vinod V. T. P., Cernic M., Sharma P. Magnetic behaviour of sol–gel driven BiFeO3 thin fi lms with different grain size distribution. Journal of Magnetism and Magnetic Materials, 2016, v. 401, pp. 180–187. https://doi.org/10.1016/j.jmmm.2015.10.035 Nikitin M. P., Vetoshko P. M., Nikitin P. I., Bnjsentsov N. A. Highly sensitive room temperature method of non-invasive in vivo Detection of magnetic nanoparticles. Journal of Magnetism and Magnetic Materials, 2009, v. 321. pp. 1658−1661. https://doi.org/10.1016/j.jmmm.2009.02.108 Vetoshko P., Skidanov V., Stempkovskiy A. Magnetization distribution near edge of YIG fi lm core in fluxgate magnetometer. Sensor Letters, 2013, v. 11(1), 59−61. https://doi.org/10.1166/sl.2013.2768 Berezhnaya M. V., Mittova I. Y., Viryutina E. L., Perov N. S., Bessalova V. V., Al’myasheva O. V., Nguyen A. T., Mittova V. O. Production of zinc-doped yttrium ferrite nanopowders by the sol–gel method. Russian Journal of Inorganic Chemistry, 2018, v. 63(6), pp. 742−746. https://doi.org/10.1134/S0036023618060049 Berezhnaya M. V., Perov N. S., Almjasheva O. V., Mittova V. O, Nguyen A. T., Mittova I. Ya., Druzhinina L. V., Alekhina Yu. A. Synthesis and magnetic properties of barium-doped nanocrystal lanthanum orthoferrite. Russian Journal of General Chemistry, 2018, v. 89(3), pp. 480−485. https://doi.org/10.1134/S1070363219030198 Nguyen A. T., Pham Vinh N. T., Nguyen T. Tr. L., Mittova V. O., Vo Q. M., Berezhnaya M. V., Mittova I. Ya., Do Tr. H., Chau H. D. Crystal structure and magnetic properties of perovskite YFe1–xMnxO3 nanopowders synthesized by co-precipitation method. Solid State Sciences, 2019, v. 96, p. 105922. https://doi.org/10.1016/j.solidstatesciences.2019.06.011 Nguyen А. Т., Berezhnay M. V., Pham T. L., Mittova V. O., Vo Q. M., Nguyen T. Tr. L., Do Tr. H., Mittova I. Ya., Viryutina E. L. Synthesis and magnetic characteristics of neodymium ferrite powders with perovskite structure. Russian Journal of Applied Chemistry, 2019, v. 92(4), pp. 498−504. https://doi.org/S1070427219040050 Milyaeva I. A., Perov N. S., Bessalova V. V., Berezhnaya М. V., Mittova V. О., Nguyen A. T., Mittova I. Ya. Synthesis and properties of nanoscale fi lms of the Y2O3–Fe2O3 system on silicon. Nanosystems: physics, chemistry, mathematics, 2018, v. 9(3), pp. 417–423. https://doi.org/10.17586/2220-8054-2018-9-3-417-423 Ievlev V. M. Aktivatsiya tverdofaznykh protsessov izlucheniyem gazorazryadnykh lamp [Activation of solid-phase processes by radiation of gas-discharge lamps]. Russian Chemical Reviews, 2013, v. 82(9), pp. 815−834. https://doi.org/10.1070/RC2013v082n09ABEH004357 JCPDC PCPDFWIN: A Windows Retrieval/Display program for Accessing the ICDD PDF – 2 Data base, International Centre for Diffraction Data, 1997. Monina L. N. Rentgenografi ya. Kachestvennyy rentgenofazovyy analiz [Roentgenography qualitative X-ray phase analysis], M.: Prospect Publ., 2017, 130 p. (in Russ.). Tretyakov N. N., Mittova I. Y., Sladkopevtsev B. V., Samsonov A. A., Andreenko S. Y. Effect of a magnetron-sputtered MnO2 layer on the thermal oxidation kinetics of InP and the composition and morphology of the resultant fi lms. Inorganic Materials, 2017, v. 53(1), pp. 65−71. https://doi.org/10.1134/S0020168517010174

Abstract Background Cardiovascular diseases are linked with oxidative stress which is the source of reactive oxidative and nitrative species, contributors of post-translational modification. Fibrinogen due to its high concentration in blood is considered as one of the most sought of targets of oxidative stress substances. Post-translational modifications of fibrinogen might influence its physiological function, thus affect hemostasis in the terms of fibrin nets forming and architecture or interaction with platelets. The aim of this study was to observe influence of in vivo fibrinogen modifications on formation of fibrin net and to identify amino acid residues prone to changes related to oxidative stress. Methods Plasma samples were collected from patients of The Military University Hospital Prague in the agreement with ethical committees of participating institutions and with informed consents from all subjects. Samples were divided into 4 groups: patients with acute coronary syndrome (A), patients with stroke (B), patients with thrombus localized in carotid vein (C) and control group (patients without coronary atherosclerosis; D). Fibrin net architecture was studied by scanning electron microscopy (Mira 3 LMH, Tescan Orsay Holding, a.s., Brno, Czech Republic). For identification of modified amino acids residue mass spectroscopy was used (Triple TOF 6600, Sciex). Molecular dynamics simulations of hydrated protein were performed in Gromacs software with Gromos force fields. Crystal structure 3GHG was used as a reference structure to which post-translational modifications were introduced manually in Yasara View. Results We found extensive both qualitative and quantitative changes in the structure of fibrinogen molecule in all groups of patients. Oxidative stress level differed among patient groups and between the control group. Different oxidative changes caused by in vivo modifications of fibrinogen affected quite distinctly the architecture of fibrin net. Modified amino acids were detected in all three fibrinogen chains. In gamma chain the localisation of modified amino acid residues correlated with the part of fibrinogen important for fibrin polymerisation. The impact of the most pronounced post-translational modifications on the secondary structure of fibrinogen was described by molecular dynamics simulations. Conclusions The results show that the degree of impairment of fibrinogen functions in the cardiovascular diseases is related to the level of oxidative stress. Characterization of oxidative fibrinogen modification and its precise meaning to the function of fibrinogen in hemostasis appears to be extremely helpful to better understanding of thrombotic/bleeding complications linked with various cardiovascular diseases. Acknowledgments This work was supported by the Ministry of Health, Czech Republic, no. 00023736, by the Academy of Sciences, Czech Republic no. P205/12/G118 and NV18-08-00149, by ERDF OPPK CZ.2.16/3.1.00/24001 and by the European Regional Development Fund and the state budget of the Czech Republic (project AIIHHP: CZ.02.1.01/0.0/0.0/16_025/0007428, OP RDE, Ministry of Education, Youth and Sports). Disclosures No relevant conflicts of interest to declare.

The aim of the article is to describe psycholinguistic meanings of the word-stimulus “playfulness” in the linguistic world-image of the Russian-speaking population of Ukraine. The main method of the conducted research was the psycholinguistic experiment. The sample according to the criteria “gender” (males and females – included both age groups) and “age” (18-35 and 36-60) included 1,600 respondents with 400 people in each sub-group of respondents. The overall number of reactions to stimulus “playfulness” comprised 1,600 associative reactions with 475 unique associations including word combinations and sentences, where 159 reactions have frequency over 1,316 individual associations, and 0 refusals. The semantic interpretation of the results of the free association test made it possible to single out 19 psycholinguistic meanings, 12 out of them accounted for more than 1%: 1) “cheerful and joyful state”, 2) “intention to attract the attention of the opposite or one’s own sex”, 3) “child-like spontaneity”, 4) “agility, physical activity of an animal”, 5) “daring and provocative behavior”, 6) “agility, physical behavior of a human being”, 7) “ease”, 8) “changeability”, 9) “behavior during a sexual intercourse”, 10) “carelessness”, 11) “mental activity”, 12) “deliberate deceit”. Taking into account the respondents’ verbal behavior, the following components of playfulness were identified: flirting, impishness, humor, fugue (eccentricity), ease, imagination. The formulated psycholinguistic meanings of playfulness can be fully considered as such that give the most adequate and reliable model of the systemic significance of the studied word and which reflects the reality of linguistic consciousness. References Barnett, L. A. (2007). The nature of playfulness in young adults. Personality and Individual Differences, 43, 949-958. Bowman, J. R. (1987). Making work play. In: Meaningful play, playful meanings. (pp. 61-71). G.A. Fine (Ed.), Champaign, IL: Human Kinetics. Bundy, A. C. (1996). Play and playfulness: what to look for. In: Play in Occupational Therapy for Children, (pp. 52-66). D. L. Parham & L. S. Fazio (Eds.). St. Louis, MO: Mosby. Chandler, B. E. (1997). The essence of play: a child’s occupation. Bethesda, MD: American Occupational Therapy Association, Inc. Glynn, M. A., Webster, J. (1992). The adult playfulness scale: An initial assessment. Psycho­logical Reports, 71(1), 83-103. Gordiienko-Mytrofanova, I. V. (2014a). Leksikograficheskoie znacheniie slova “igrivost” (podgo­to­­­vitelnyi etap psikholingvisticheskogo eksperimenta) [The lexicographic meaning of the word “playfulness” (the preparatory stage of the psycholinguistic experiment)]. Psychological Prospects Journal, 24, 65-77. Gordiienko-Mytrofanova, I. V. (2014b). Psikhologicheskoie soderzhaniie leksikograficheskikh znachenii slova “igrivyi” (podgotovitelnyi etap psikholingvisticheskogo eksperimenta) [The psychological content of the lexicographic meanings of the word “playful” (the preparatory stage of the psycholinguistic experiment)]. Problemy suchasnoi pedahohichnoi osvity – Problems of Modern Pedagogical Education, 45(2), 419-430. Gordiienko-Mytrofanova, I. V. (2014c). Psikhologicheskaia interpretatsiia leksikograficheskogo opisaniia slova “igrivyi” [Psychological interpretation of the lexicographic description of the word “playful”]. Problemy Suchasnoi Psykholohii – Problems of Modern Psychology, 25, 83-98. Gordienko-Mytrofanova, I., Sypko, A. (2015). Playfulness as a relevant lexeme in the bilingual linguistic consciousness of Ukrainian people. East European Journal of Psycholinguistics, 2(1), 43-51. Gordienko-Mytrofanova, I., Sauta, S. (2016). Playfulness as a peculiar expression of sexual relationships (semantic interpretation of the results of the psycholinguistic experi­ment). European Humanities Studies: State and Society, 1, 46-62. Gordienko-Mytrofanova, I., Kobzieva, I. (2017). Humor as a component of ludic competence. Visnyk [Journal] of the Hryhorii Skovoroda Kharkiv National Pedagogical University, 57, 40-56. Gordienko-Mytrofanova, I., Kobzieva, I. (2018). Concept «Holy Fool» in the Linguistic World-Image of the Russian-Speaking Population of Ukraine. Psycholinguistics, 24(1), 118-133. Gordiienko-Mytrofanova, I., Pidchasov, Y., Sauta, S. Kobzieva, I. (2018). The problem of sample representativeness for conducting experimental and broad psychological research. Psycholinguistics, 23(1), 11-46. Guitard, P., Ferland, F., & Dutil, É. (2005). Toward a better understanding of playfulness in adults. OTJR: Occupation, Participation and Health, 25(1), 9-22. Kondakov, N. I. (1975). The Logical Dictionary-Reference. Moscow: Nauka. Proyer, R. T. (2012). A Psycho-linguistic Study on Adult Playfulness: Its Hierarchical Structure and Theoretical Considerations. Journal of Adult Development, 19(3), 141-149. Proyer, R.T. (2014). A Psycho-Linguistic Approach For Studying Adult Playfulness: A Replication and Extension Toward Relations With Humor, The Journal of Psychology, 148(6), 717-735. Proyer, R.T. (2017). A new structural model for the study of adult playfulness: Assessment and exploration of an understudied individual differences variable. Personality and Individual Differences, 108, 113-122. Rudakova, A. V. (2015). On the concept of an integrated lexicographic meaning of a word and the methodology of its description. Culture of Communication and Its Formation: Interuniversity Collection of Scientific Works, 31, 109-115. Schaefer, C. & Greenberg, R. (1997). Measurement of Playfulness: A Neglected Therapist Variable. International Journal of Play Therapy, 6(2), 21-31. Shen, X. (2010). Adult playfulness as a personality trait: Its conceptualization, measurement, and relationship to psychological well-being. Doctoral dissertation. Retrieved from Pennsylva­nia State University Library Catalog (OCLC No. 859524715). Sternin, I.A., & Rudakova, A.V. (2011). Psikholingvisticheskoie znacheniie slova i yego opisaniie [Psycholinguistic meaning of the word and its description]. Voronezh: Lambert. Tsuji, Hit., Tsuji, Hei., Yamada, S., Natsuno, Y., Morita, Y., Mukoyama, Y., Hata, K., Fujishima, Y. (1996). Standardization of the Five Factor Personality Questionnaire: Factor structure. International Journal of Psychology, 31. Proceedings from the XXVI International Congress of Psychology. August 16–21, 1996, Montreal, Canada. (103-217). Ufimtseva, N. V. (2009). Obraz mira russkikh: sistemnost i soderzhaniie [Image of the world of Russians: the systemic characteristics and the content]. Yazyk i kultura – Language and Culture, 98-111. Yarnal, C., & Qian, X. (2011). Older-adult Playfulness: An innovative construct and measure­ment for healthy aging research. American Journal of Play, 4(1), 52-79. Yue, X. D., Leung, C. L., Hiranandani, N. A. (2016). Adult Playfulness, Humor Styles, and Subjective Happiness. Psychological Reports, 119(3), 630-640.