Academic literature on the topic 'C-FRCM'

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Journal articles on the topic "C-FRCM"

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Iorfida, Antonio, Sebastiano Candamano, Fortunato Crea, Luciano Ombres, Salvatore Verre, and Piero de Fazio. "Bond Behaviour of FRCM Composites: Effects of High Temperature." Key Engineering Materials 817 (August 2019): 161–66. http://dx.doi.org/10.4028/www.scientific.net/kem.817.161.

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The fire remains one of the serious potential risks to most buildings and structures, as recently it’s been witnessed in Paris’ historic Notre Dame Cathedral and London’s Grenfell Tower. Concrete and masonry construction materials suffer physiochemical changes and mechanical damage caused by heating that is usually confined to the outer surface but can eventually compromise their load-bearing capacity. FRCM systems could provide when applied, supplemental fire insulation on pre-existing structural members, but there is a lack of knowledge about their properties in those conditions. This experimental work, thus, aims to evaluate the mechanical behaviour of carbon-FRCM and basalt-FRCM composites bonded to masonry substrate after high temperature exposure. Temperatures of 100 °C, 300 °C and 500 °C over a period of three hours were used to investigate the degradation of their mechanical properties. Single lap shear bond tests were carried out to evaluate the bond-slip response and failure modes. For all the tested temperatures higher peak stresses were measured for carbon-FRCM composite than basalt ones. Furthermore, low-density basalt-FRCM composite showed higher peak stresses and lower global slips up to 300 °C than high-density one. Carbon-FRCM composite failure mode was not effected by temperature. High-density basalt-FRCM composite showed a change in failure mode between 300 °C and 500 °C.
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Ombres, Luciano. "Confinement Effectiveness in Eccentrically Loaded Masonry Columns Strengthened by Fiber Reinforced Cementitious Matrix (FRCM) Jackets." Key Engineering Materials 624 (September 2014): 551–58. http://dx.doi.org/10.4028/www.scientific.net/kem.624.551.

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Abstract.The paper is devoted to the analysis of the effectiveness of the Carbon Fiber Reinforced Cementitious Matrix (C-FRCM) as confinement system of the masonry and the characterization of the structural response of masonry column confined by C-FRCM jackets, accounting for all geometrical and mechanical involved parameters. At this aim, tests on confined masonry column under eccentric axial load were carried out. Five masonry column having an overall length of650 mm, with rectangular cross-section,250 x250 mm, were eccentrically loaded until collapse; two specimens were un-confined and used as control specimens, two specimens were confined with one layer of C-FRCM and one specimen was confined with two layers of C-FRCM. The eccentricity values considered weree/H=0ande/H=0.20, being H the height of the section. Failure modes and load-strain diagrams were considered to analyze test results and to evaluate the effectiveness of the confinement both in terms of strength and ductility.
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Riaz, Saman, Ali Arshad, and Licheng Jiao. "Fuzzy Rough C-Mean Based Unsupervised CNN Clustering for Large-Scale Image Data." Applied Sciences 8, no. 10 (October 10, 2018): 1869. http://dx.doi.org/10.3390/app8101869.

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Deep learning has been well-known for a couple of years, and it indicates incredible possibilities for unsupervised learning of representations with the clustering algorithm. The forms of Convolution Neural Networks (CNN) are now state-of-the-art for many recognition and clustering tasks. However, with the perpetual incrementation of digital images, there exist more and more redundant, irrelevant, and noisy samples which cause CNN running to gradually decrease, and its clustering accuracy decreases concurrently. To conquer these issues, we proposed an effective clustering method for a large-scale image dataset which combines CNN and a Fuzzy-Rough C-Mean (FRCM) clustering algorithm. The main idea is that first a high-level representation, learned by multi-layers of CNN with one clustering layer, produce the initial cluster center, then during training image clusters, and representations, are updating jointly. FRCM is utilized to update the cluster centers in the forward pass, while the parameters of proposed CNN are updated by the backward pass based on Stochastic Gradient Descent (SGD). The concept of the rough set of lower and boundary approximations deal with uncertainty, vagueness, and incompleteness in cluster definition, and fuzzy sets enable efficient handling of overlapping partitions in the noisy environment. The experiment results show that the proposed FRCM based unsupervised CNN clustering method is better than the standard K-Mean, Fuzzy C-Mean, FRCM and also other deep-learning-based clustering algorithms on large-scale image data.
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Feng, Ran, Yuexin Liu, Ji-Hua Zhu, and Feng Xing. "Flexural behaviour of C-FRCM strengthened corroded RC continuous beams." Composite Structures 245 (August 2020): 112200. http://dx.doi.org/10.1016/j.compstruct.2020.112200.

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Zhu, Ji-Hua, Ju Chen, Yuan Feng, and Cheng-Bin Liu. "Compression tests of C-FRCM jacket confined hollow section RC columns." Structures 31 (June 2021): 961–69. http://dx.doi.org/10.1016/j.istruc.2021.02.044.

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Zhu, Ji-Hua, Zhi Wang, Mei-ni Su, Tamon Ueda, and Feng Xing. "C-FRCM Jacket Confinement for RC Columns under Impressed Current Cathodic Protection." Journal of Composites for Construction 24, no. 2 (April 2020): 04020001. http://dx.doi.org/10.1061/(asce)cc.1943-5614.0001006.

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Jurina, Lorenzo, Giovanni Mantegazza, and Edoardo Oliviero Radaelli. "FRCM - Strenghtening of Masonry Vaults: The “Duomo Di Colorno” and “Braidense Library” Cases in Italy." Key Engineering Materials 624 (September 2014): 494–501. http://dx.doi.org/10.4028/www.scientific.net/kem.624.494.

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In the last decade a re-discovering of the construction techniques and materials belonging to ancient buildings and heritage has grown up.Professionals and researchers have made a strong effort to understand resisting mechanisms in masonry buildings, trying to evaluate the safety factor in presence of vertical and horizontal seismic loads. As a consequence, innovative techniques and materials, as the FRCM, have been introduced to prevent local and global collapse mechanism, increasing the safety of the overall structure.The special cases of “Duomo of Colorno” and the “Braidense Library”, in Italy, are here presented.The XVIII century masonry vaults of the Duomo widely suffered due to a seismic event occurred in 2012 and a relevant crack pattern appeared.A similar situation occurred for the barrel vault of the Braidense Library due to settlement of foundations.In both cases, in order to restore the global resistance of the building, some consolidation interventions have been proposed.One of those is represented by a FRCM net applied on the upper side of the vaults. The system makes use of a carbon bi-directional fiber net inserted in an inorganic pozzolanic matrix, fully compatible with the ancient masonry support.A numerical non-linear analysis of the cathedral and of the barrel vault of the Braidense Library has demonstrated an increment up to 25% in the value of the horizontal loads that cause the formation of the first cracks, if compared with the non-consolidated situation.Furthermore, besides this passive fiber intervention, an innovative active technique called “RAM – Reinforced Arch Method” was applied on the vaults of the Duomo. The use of post-tensioned steel cables, added to the FRCM net, led to a strong increase of the horizontal collapse load.Carbon fibers are able to induce a strong increase in the resistance of the masonry under the tensile stresses caused by seismic loads, avoiding the formation of cracks or plastic hinges.Several tests have been performed on FRCM, according to Standards.In tensile and lap-tensile strength tests, the stress-strain behavior of C-FRCM control coupon specimens is bi-linear as expected. The initial branch of the curve corresponds to the un-cracked specimen, followed by a second branch with a reduced slope, corresponding to the crack specimen.The primary failure mode of the C-FRCM coupon specimens was slippage of the fibers after multiple cracking throughout the length of the specimen, perpendicular to the direction of the load, secondary de-bonding failure mode located at the tab ends was observed in some cases.Furthermore, all tensile and lap-tensile strength coupon tests passed the conditions of acceptance as per the requirements regarding environmental exposure to Freezing and Thawing, and Aging.
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Chen, Ju, Jun Wang, Ji-Hua Zhu, Yuan Feng, and Cheng-Bin Liu. "Study on the Corroded Hollow Section RC Columns Strengthened by ICCP-SS System." Buildings 11, no. 5 (May 8, 2021): 197. http://dx.doi.org/10.3390/buildings11050197.

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In this paper, the behavior of corroded hollow section RC (reinforced concrete) columns strengthened by an Impressed Current Cathodic Protection and Structural Strengthening (ICCP-SS) system was investigated. The Carbon Fabric-Reinforced Cementitious Matrix (C-FRCM) composite serves dual functions in the intervention method. The axial compression behavior of strengthened columns was firstly investigated through axial compression tests. The influence of corrosion ratio and C-FRCM strengthening on the test results, such as failure mode, load–displacement curve, ultimate load, and ultimate strain, were analyzed. Test results showed that the ultimate load of the corroded specimens could be enhanced significantly by C-FRCM, and the ductility of the strengthened specimens was larger than the specimens without strengthening, especially for the specimens with higher corrosion ratios. Secondly, the effects of the ICCP-SS system on the migration and distribution laws of chloride ions (Cl−) in hollow section RC columns were analyzed by the potentiometric titration method. The main parameters include charging time, current density, and salt addition. Results showed that the rebar would have a certain blocking effect on the migration of Cl−, which resulted in that the content of Cl− in the inner side of the rebar was always larger than that of the outer side; and research results also showed that the increase of impressed current density and charge time would reduce the Cl− content on both sides of the rebar, while the impressed current would cause the Cl− near the rebars to constantly move toward the vicinity of CFRP.
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Feng, Ran, Jingzhou Zhang, Ji-Hua Zhu, and Feng Xing. "Experimental study on interface bonding fatigue behavior of C-FRCM composites in ICCP." Construction and Building Materials 259 (October 2020): 119660. http://dx.doi.org/10.1016/j.conbuildmat.2020.119660.

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Feng, Ran, Yanwen Li, Ji-Hua Zhu, and Feng Xing. "Behavior of corroded circular RC columns strengthened by C-FRCM under cyclic loading." Engineering Structures 226 (January 2021): 111311. http://dx.doi.org/10.1016/j.engstruct.2020.111311.

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Dissertations / Theses on the topic "C-FRCM"

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De, Nigris Stefano. "Prove cicliche di trazione e aderenza su muretti in laterizio rinforzati con FRCM." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2017.

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Le tipologie di prova adottate durante i test condotti su campioni FRCM sono state essenzialmente due: prove di trazione e prove di aderenza, svolte impiegando due diverse modalità di applicazione del carico (caricamento monotono e/o ciclico) e due diverse tipologie di rinforzo (una in fibra di carbonio e una in fibra di vetro). Nel corso delle prove di trazione, i risultati migliori sono stati ottenuti per i rinforzi in fibra di carbonio con applicazione del carico di trazione monotona, quindi per la soluzione in cui si è utilizzata la fibra avente le caratteristiche meccaniche migliori; il comportamento di questi materiali è risultato tuttavia peculiare, in quanto lo strato di malta esterno ha mostrato spesso distacchi e perdita di adesione rispetto alla rete bidirezionale di rinforzo, rendendo difficoltosa la misura esterna della deformazione del composito. I rinforzi in fibra di vetro (GFRCM) hanno mostrato risultati inferiori in termini di tensione massima, in accordo con la tipologia di fibra impiegata, ma hanno evidenziato un comportamento caratterizzato si dall’apertura di fessure, ma maggiormente assimilabile ad una schematizzazione trilineare, senza fenomeni evidenti di distacco esterno della matrice prima della rottura. Dalla sperimentazione dei provini mediante prove di aderenza è emerso che, sia nel caso di prove monotone che cicliche, i provini rinforzati con GFRCM hanno mostrato un’efficienza maggiore. La rete in fibra di vetro ha mostrato una aderenza migliore all’interno della matrice cementizia, rispetto alla rete in fibra di carbonio, perché presenta uno speciale trattamento superficiale (appretto) che ne migliora la compatibilità e l’adesione al supporto. I rinforzi GFRCM testati hanno sfruttato al meglio le proprie caratteristiche meccaniche raggiungendo valori di carico maggiori (circa doppi) rispetto ai rinforzi CFRCM.
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Arslan, Guray. "Strengthening Of Reinforced Concrete Frames By Custom Shaped High Strength Concrete Masonry Blocks." Master's thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/2/12610335/index.pdf.

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Located on one of the highly active seismic fault systems in the world, the building stock in Turkey is mainly composed of reinforced concrete frames with 4-5 stories. Due to design and construction deficiencies resulting from the use of unqualified personnel and insufficient supervision, many of these buildings lack lateral stiffness, ductility and strength. For many structures, there is a need to alleviate these deficiencies by means of some rehabilitation techniques prior to earthquakes. One approach also used very widely in Turkey is to fill some of the frame bays by cast-in-place R/C panels. The procedure appears to be very practical at first glance. It also appears to be very economical as far as the production of the panels is concerned. However, the production phase is slow, dirty, destructive and disruptive to occupants. Moreover, it requires relatively skilled personnel and special equipment. Therefore, the real life experience shows that the actual cost in practice is much higher when all other hidden costs are taken into account. The aim of this experimental study is to explore the potential of using infill walls made of custom shaped and high strength concrete blocks as a simpler and more practical alternative to cast-in-place R/C panels to increase the lateral load bearing capacity of frame structures. The effectiveness of FRCM (Fiber Reinforced Cementitous Matrix) system on damaged structures is also investigated in this study.
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Books on the topic "C-FRCM"

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Slade, Krista. "The Ankh: F. Marguerite Hill, MD, FRCP (C), a life of teaching and healing". [Canada: s.n.], 1992.

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Phillips, Reed B. The journey of Scott Haldeman, DC, PHD, MD, FRCP(C), FAAN, FCCS(C): Spine care specialist & researcher forging international interdisciplinary cooperation. [Des Moines, Iowa]: National Chiropractic Mutual Holding Company, 2009.

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Harrison, Mark. Hepatitis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198765875.003.0025.

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This chapter describes the microbiology of hepatitis as it applies to Emergency Medicine, and in particular the Primary FRCEM examination. The chapter outlines the key details of the epidemiology, clinical features, basis of diagnosis, medical management, and prevention of hepatitis A, B, and C. This chapter is laid out exactly following the RCEM syllabus, to allow easy reference and consolidation of learning.
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Harrison, Mark. Inflammatory response. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198765875.003.0054.

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This chapter describes the pathology of inflammatory response as it applies to Emergency Medicine, and in particular the Primary FRCEM examination. The chapter outlines the key details of normal vs abnormal response, and inflammatory markers including C-reactive protein, rheumatoid factor, and antinuclear factor. This chapter is laid out exactly following the RCEM syllabus, to allow easy reference and consolidation of learning.
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Harrison, Mark. Principles of immunization. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198765875.003.0012.

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This chapter describes the principles of microbiology immunization as they apply to Emergency Medicine, and in particular the Primary FRCEM examination. The chapter outlines the key details of immunization schedules for diphtheria, tetanus, pertussis, Haemophilus influenzae type b, polio, Pneumococcal infection, MMR, meningitis C, HPV, varicella, hepatitis B, and influenza, as well as further sources of information. This chapter is laid out exactly following the RCEM syllabus, to allow easy reference and consolidation of learning.
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Prout, Jeremy, Tanya Jones, and Daniel Martin. Core topics in intensive care medicine. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199609956.003.0020.

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This chapter on aspects of intensive care for FRCA commences with the recognition of the critically ill patient, use of early warning scores, outreach teams and the systematic assessment of the acutely ill patient. Sepsis has been a recent focus area for healthcare systems; the definition of sepsis, pathophysiological processes leading to organ dysfunction and management including early goal-directed therapy, supportive techniques and the role of specific therapies such as steroids and activated protein C are included. Acute lung injury and respiratory distress syndrome with management and specific ventilatory strategies are described. Important aspects of providing sedation and analgesia on intensive care are explained as well as the complex ethical aspects of this speciality with regards to consent and end-of-life decisions
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Book chapters on the topic "C-FRCM"

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Gonzalez-Libreros, J. H., C. Pellegrino, and G. Giacomin. "R. C. Beams Strengthened on Shear with FRP and FRCM Composites." In Lecture Notes in Civil Engineering, 400–410. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78936-1_29.

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Conference papers on the topic "C-FRCM"

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JUDE, B., A. WATEL, D. FONTAINE, P. FONTAINE, and A. COSSON. "DISTINCTIVE FEATURES OF PROCOAGULANT RESPONSE OF MONOCYTES FROM DIABETIC PATIENTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643103.

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Hypercoagulability is one of the possible factors reported in genesis or aggravation of vascular complications in diabetes mellitus. We therefore examined procoagulant activity (PCA) of disrupted monocytes frcm 26 patients with Type I diabetes and 6 with Type II, versus 32 control subjects (male/ female ratio = 1 in each group).Diabetes monocytes exhibited a slight but detectable PCA before any incubation or in vitro stimulation, whereas control monocytes did not. Data obtained with coagulation factor deficient plasmas or phospholipase C indicated that PCA was tissue factor (TF) alone in 22 cases and TF associated with a significant amount of factor VII/VIIa activity in 10 cases.Incubation in serum free medium led to significant raise of PCA in diabetes cells when stimulated with endotoxin or not, and in control cells only after stimulation. Furthermore, PCA appeared earlier in diabetes monocytes than in control ones, (4 hours, versus 20 hours). PCA frcm control cells was FT-like. PCA frcm diabetes cells was FT-like when no VII/VIIa activity was present on non-stimulated cells, and prothrombinase-like when VII/VIIa activity was early associated with the cells. In the latter case, trace amounts of factor X activity were also detectable. Whether factor VII and factor X activities were of plasmatic origin and associated to the cells, or synthesized in vitro by the cells remains unclear. The characteristics of PCA were net correlated with clinical features (age, diabetic complications) nor with the type of diabetes.Our data suggest that in diabetes patients, monocytes exhibit an increased PCA, possibly corresponding to a baseline stimulation, or at least a higher responsiveness to undergoing stimuli in vitro.
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Lipinski, B., J. Ewaskiewicz, S. Niewiarowski, and A. Z. Budzynski. "STRUCTURE AND FUNCTIONAL PROPERTIES OF A FIBRINOGEN EERIVATIVE FORMED BY LIMITED PROTEOLYSIS WITH RED BLOOD CELL." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643329.

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Normal human plasma contains, in addition to fibrinogen (Mr 340,000), two major thranbin-coagulable fibrinogen derivative of Mr 320,000 and 300,000. Previous investigations demonstrated that these derivatives do not originate from plasmic cleavages, however, no enzyme(s) responsible for the cleavages have been identified. The purpose of this study was to investigate a possible role of red blood cells (RBC) in the formation of these physiologic fibrinogen derivatives. RBC ghosts were prepared from ACD blood obtained from normal donors after removal of leukocytes and platelets. Purified human fibrinogen, that contained only one band of Mr 340,000 as judged by SD6-PAGE, was incubated with RBC ghosts at 37°C. SDS-PAGE of the supemate revealed the presence of a single band of approximate Mr 275,000 after one hour of incubation. Proteolytic degradation of fibrinogen by RBC ghosts was inhibited by STI but not by trasylol, leupeptin or EDTA suggesting that putative enzyme is distinct frcm plasmin and calpain. Polypetide chain ánalysis of Mr 275,000 derivative demonstrated degradation of its A alpha chain. The derivative shewed an impaired binding to AEP-activated platelets as shown by decreased number of fibrinogen binding sites calculated frcm Scatchard plots.Study of polymerization reaction of Mr 275,000 derivative catalyzed by thrombin revealed significantly impaired kinetics.The maximum polymerization rate of Mr 275,000 monomers was 51% of that of intact fibrinogen. The data suggest that RBC ghosts contain enzyme (s) that are capable to induce a limited proteolytic degradation of fibrinogen that may contribute to alteration of its biologic functions inportant in hemostasis and thrombosis.
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Matsumoto, T., K. Kanamaru, Y. Sugiyama, and K. Deguchi. "HEMATOLOGICAL CHARACTERISTICS OF PREGNANT BLOOD AND LOCALIZATION OF THROMBOMODULIN IN HUMAN PLACENTAL VILLOUS TISSUE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644299.

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Thrombomodulin(TM) is a cell surface protein found on endothelial cell that binds thrombin and increases thrombin's ability to activate protein C(PC). In the present study, we examined hematological characteristics and behavior of plasma PC level in pregnant women and localization of TM in the placental villous tissue. The results obtained are reported here. Cubital venous blood of 20 normal pregnants, 8 purperants and 60 non-pregnants. PC antigen(PC:Ag) was measured by the Laurell's technique using Assera plate-proteinC. Localization of TM was determined in such a way that the villous tissue was fixed in formalin, cut into paraffin sections, and stained by ABC method using anti-TM antibody. Coagulation-related factors of the pregnant blood, i.e. fibrinogen, FV, FVIII, FX, FXII and prekallikren showed statistically higher values compared with the control group, and AT-III showed almost simillar value to the control group or tended to decrease to scxne extent compared therewith. As for fibrinolysis-related factors, on the other hand, plasminogen, α1-antitripsin showed higher values with the progress of pregnancy, and α2-macro_ globulin showed slightly lower values in both 3rd trimester and puerperal stage. PC:Ag increased in the 2nd and 3rd trimester (p<0.01). Comparative examinations made of PC:Ag level between pre- and post-taking oral centraceptives revealed a significant (p<0.05) decrease frcm 131.0%( pre-taking) to 117.0%(post-taking). At the 11th week of pregnancy, TM was confirmed to be highly localized in syncytiotrophoblast in the villous tissue, especially in microvilli. At the 40th week, TM was also confirmed in the same site, but with weaker stainability. It was suggested that thrombosis and hemostasis-related factors were in a state of co-existing overproduction and consumption. Moreover we supposed that the existence of TM and the increase in PC might be just appropriate for the maintenance of anti-thrombogenesis in the uteroplacental circulation.
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Tripp, Charles, David Hyde, and Benjamin Grossman-Ponemon. "FRC: a high-performance concurrent parallel deferred reference counter for C++." In ISMM '18: The International Symposium on Memory Management 2018. New York, NY, USA: ACM, 2018. http://dx.doi.org/10.1145/3210563.3210569.

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Herbell, Thomas P., and Andrew J. Eckel. "Ceramic Matrix Composites for Rocket Engine Turbine Applications." In ASME 1992 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1992. http://dx.doi.org/10.1115/92-gt-394.

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A program to establish the potential for introducing fiber reinforced ceramic matrix composites (FRCMC) in future rocket engine turbopumps was instituted in 1987. A brief summary of the overall program (both contract and in-house research) is presented. Tests at NASA Lewis include thermal upshocks in a hydrogen/oxygen test rig capable of generating heating rates up to 2500 °C/sec. Post thermal upshock exposure evaluation includes the measurement of residual strength and failure analysis. Test results for monolithic ceramics and several FRCMC are presented. Hydrogen compatibility was assessed by isothermal exposure of monolithic ceramics in high temperature gaseous hydrogen plus water vapor.
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Kruithof, E. KO, W. D. Schleuning, and F. Bachman. "PLASMINOGEN ACTIVATOR INHIBITOR BIOCHEMICAL AND CLINICAL ASPECTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644764.

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Plasminogen activator (PAs) are enzymes that convert the zymogen plasminogen into the trypsin-like protease plasmin, which degrades extracellular matrix proteins and fibrin in the course of fibrinolysis, embryogenesis, tissue remodeling and in tumor metastasis. Plasminogen activator inhibitors (PAIs) are important modulators of PA activity. Several proteins have been identified which inhibit at fast rates urokinase (u-PA) and tissue-type PA (t-PA). In the order of inhibition rate constants these are: a) PAI-1, present in human plasma and platelet extracts and purified from human endothelial cell, fibrosarcoma cell and melanoma cell conditioned media; b) PAI-2, first identified in extracts of human placenta and later also in extracts and conditioned media of human granulocytes and monocytes; and c) protease nexin, a broad specificity protease inhibitor that was first identified and purified from human fibroblasts. We have chosen to use phorbol myristate acetate (30 ng/ml) stimulated histiocytic lymphoma cells (U-937) for the purification of PAI-2. The concentration of PAI-2 in the conditioned media after three days culture in the absence of fetal calf serum is 5 mg/1 and PAI-2 represents 3% of total protein. PAI-2 was purified by a two step procedure consisting of isoelectric focusing and affinity chromatography on Cibacron-Blue agarose. Two forms of PAI-2 were identified: a 47 kDa, nonglycosylated, pi 5.0 form and a 60 kDa glycosylated, pi 4.4 form. Immunctolot analysis and in vivo protein labeling studies under culture conditions that assure 100% viability of the cells showed that the glycosylated Torn is secreted, whereas the 47 kDa, nonglycosylated form remains intracellular. The glycosylation does not affect the activity of the inhibitors since both forms of PAI-2 react with the same rate with u-PA. PAI-2 is a fast inhibitor of u-PA (kl=9×l05M−1s−1) and two-chain t-PA (kl=2×l05) and a rather slow inhibitor of one chain t-PA (kl=l×l02) and of plasmin (kl×l02), but does not inhibit glandular and plasma kallikrein or thrombin. The inhibition spectrum and the kinetics of inhibition clearly distinguish PAI-2 from PAI-1 (kl of reaction with u-PA and two and one chain t-PA above 107) and from protease nexin, that is an efficient inhibitor also of thrombin and plasmin.We have cloned a 1880 Ip fragment of PAI-2 cDNA and determined its nucleotide sequence. The derived acid sequence reveals that PAI-2 is like PAI-1 and protease nexin a member of the serpin family of proteins and contains arginine at its putative active site. In an attenpt to identify parts of the inhibitor proteins that are responsible for conferring PA specificity to PAI-1 and PAI-2 we have compared the primary structures of PAI-1 and PAI-2 with each other and with antithrombin III (AT III). Surprisingly, PAI-2 exhibits no homology with PAI-1 in the region close to the active site except for the active site arginine, whereas, in that region, AT III showed three and seven conserved aminoacids when compared to PAI-1 and PAI-2, respectively. This finding suggests that other regions than those close to the active site contribute to the specificity of PAIs.Plasma concentrations of PAI-2 were measured by a specific radioimmunoassay in over 50 healthy individuals, PAI-2 levels were below detection limit (15 ng/ml) in half of the saitples. Maximal concentrations encountered were in the 30 ng/ml range. PAI-2 measurements in over 300 hospitalized patients demonstrated significantly elevated PAI-2 concentrations only in pregnant women. Measurements in various stages of pregnancy showed a steady increase of PAI-2 from below detection limit in nonpregnant women to values of 250 ng/ml at term and of PAI-1 frcm 25 ng/ml to 150 ng/ml. Unlike to PAI-1 concentrations that normalize rapidly after delivery, PAI-2 concentrations remain significantly elevated for several days.
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Osin, D., D. Gupta, and S. Korepanov. "Spectroscopic measurements of ion temperature and rotation of two ion components in C-2 FRC plasma." In 2014 IEEE 41st International Conference on Plasma Sciences (ICOPS) held with 2014 IEEE International Conference on High-Power Particle Beams (BEAMS). IEEE, 2014. http://dx.doi.org/10.1109/plasma.2014.7012333.

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Watanabe, Aklo, Tetsuo Tatsumi, Kazuhiko Tanimura, Isashi Takehara, and Tatsuo Fujii. "Development of 300 kW Class Ceramic Gas Turbine (CGT302)." In ASME 1994 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1994. http://dx.doi.org/10.1115/94-gt-019.

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Abstract:
The Japanese Ministry of International Trade and Industry (MITI) is promoting the Ceramic Gas Turbine (CGT) project for energy saving technology development under the ‘New Sunshine project’. The objective of this project is to develop a 300 kW ceramic gas turbine with 42% thermal efficiency at 1350°C turbine inlet temperature. Three types of CGT are under development for individual purposes and concepts. CGT302 is the recuperated two-shaft ceramic gas turbine for cogeneration use. Ceramic materials have many advantages in the application of high temperature gas turbines, but there are still several problems of practical use. Therefore, we introduce the unique technology of monolithic - FRC hybrid concept to fabricate large ceramic components, stress free supporting structure, joining technology, etc. The all ceramic components of the 1200°C CGT were successfully fabricated and engine tests are in progress. This paper will describe the technologies of the CGT302 development and results of engine tests.
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Reports on the topic "C-FRCM"

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Rej, D. J., W. N. Hugrass, G. A. Barnes, and R. E. Siemon. FRC formation experiments with tearing reconnection on the FRX-C/LSM device. Office of Scientific and Technical Information (OSTI), September 1986. http://dx.doi.org/10.2172/7153110.

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