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Journal articles on the topic 'C-reactive protein and inflammatory marker'

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Published: 3 June 2025

Last updated: 31 July 2025

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1

SRIKUMAR, N. "Inflammatory marker C-reactive protein in hypertensive subjects." American Journal of Hypertension 15, no. 4 (2002): A227. http://dx.doi.org/10.1016/s0895-7061(02)02886-8.

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Rocha Martinez, Tania Leme da. "Landmarks On C-Reactive Protein As Inflammation Marker." American Journal of Medical and Clinical Research & Reviews 03, no. 11 (2024): 01–04. http://dx.doi.org/10.58372/2835-6276.1221.

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C-reactive protein is a crucial biomarker for inflammation and widely used in assessing cardiovascular disease risk. Produced by the liver in response to inflammatory stimuli like infection or injury, C-reactive protein levels rise significantly during acute and chronic inflammation. High-sensitivity C-reactive protein testing detects even low-grade inflammation, providing greater accuracy in identifying cardiovascular risk. C-reactive protein relevance in cardiovascular health stems from its association with atherosclerosis, an inflammatory process that leads to plaque buildup in arteries. El

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Nyström, Thomas. "C-reactive protein: a marker or a player?" Clinical Science 113, no. 2 (2007): 79–81. http://dx.doi.org/10.1042/cs20070121.

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It has been suggested that Type 2 diabetes may, in part, be precipitated or accelerated by an acute-phase reaction as part of the innate immune response, in which large amounts of cytokines are released from adipose tissue, creating a low-grade inflammatory milieu. There is also firm evidence that atherosclerosis is an immune-mediated inflammatory disease. Therefore it is reasonable to imply that low-grade inflammation is an important pathogenetic factor in atherosclerosis and cardiovascular events in patients with Type 2 diabetes. Over the last few years, there have been a lot of promising cl

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Sevcan, Ugur. "C-reactive protein to albumin ratio, albumin to globulin ratio and platelet to lymphocyte ratio in patients with spondyloarthritis." Turkish Journal of Health and Sport 3, no. 1 (2022): 1–4. https://doi.org/10.29228/tjhealthsport.55675.

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Aim: The C-reactive protein (CRP) to albumin ratio (CAR) has been reported as a novel inflammatory marker to assess inflammation. Serum globulin increases in inflammation. In this study, it was aimed to evaluate relation between CAR, albumin to globülin ratio (AGR), platelet to lymphocyte ratio (PLR) and disease activity in patients with axial spondyloarthritis (AxSpA). Method: Seventy-five patients with axial SpA and seventy-five healthy controls were evaluated retrospectively. CRP, albumin, globulin, leukocyte, lymphocyte, and platelet from the patients and controls were recorded. CAR,

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Dr., Abdul Haque Khan* Dr. Muhammad Zaman Baloch Dr. Ghulam Hussain Baloch Dr. Hamid Nawaz Ali Memon Dr. Imran Karim Dr. Sajjad Ali and Dr. Samreen. "ASSOCIATION OF C-REACTIVE PROTEIN AND ESSENTIAL HYPERTENSION." Indo American Journal of Pharmaceutical Sciences 04, no. 11 (2017): 4366–69. https://doi.org/10.5281/zenodo.1064343.

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Objective: To determine the association of C-reactive protein (CRP) and essential hypertension at tertiary care hospital Patients and Methods: All the patients with ≥30 years of age, either gender with essential hypertension for ≥3 years were included in the six months cross sectional study after taking informed consent. The essential hypertension was labeled when the average of multiple systolic BP readings on two or more subsequent visits was consistently ≥140 mmHg on presentation or average of 02 or more diastolic BP measurements on at least 2 subsequent visits was ≥90 mmHg for

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Vermeire, Séverine, Gert Van Assche, and Paul Rutgeerts. "C-Reactive Protein as a Marker for Inflammatory Bowel Disease." Inflammatory Bowel Diseases 10, no. 5 (2004): 661–65. http://dx.doi.org/10.1097/00054725-200409000-00026.

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Inflammatory, markers: An Overview. "Inflammatory markers: An Overview." Science World a monthly e magazine 2, no. 11 (2022): 1845–49. https://doi.org/10.5281/zenodo.7339579.

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Inflammation is the body’s innate response to injury or insult, including infection, trauma, surgery, burns, and cancer. Certain proteins are released into the bloodstream during inflammation; if their concentrations increase or decrease by at least 25%, they can be used as systemic inflammatory markers. Although there are many inflammatory markers, also known as acute phase reactants, those most commonly measured in clinical practice are C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and procalcitonin (PCT). PCT is a newer marker of inflammation that may, in certain cas

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Torzewski, Michael, Ahmed Bilal Waqar, and Jianglin Fan. "Animal Models of C-Reactive Protein." Mediators of Inflammation 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/683598.

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As the main theme of this special issue, CRP not only is an inflammatory marker but also has diverse biological functions associated with different diseases. To investigate CRP’s physiologies and their relationship with human pathological significance, it is essential to use appropriate animal models for translational research. The most popular models for the study of CRP are transgenic mice. However, researchers should be careful when extrapolating the findings derived from these animal models. This review will discuss the current concerns on CRP transgenic mice and rabbits.

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Malin, Katarzyna, and Olga Witkowska-Piłaszewicz. "C-Reactive Protein as a Diagnostic Marker in Dogs: A Review." Animals 12, no. 20 (2022): 2888. http://dx.doi.org/10.3390/ani12202888.

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Acute phase response is a nonspecific reaction to disturbances in homeostasis during which the production of some Acute Phase Proteins (APPs) is stimulated; they are sensitive but nonspecific markers of systemic inflammatory processes. The major positive APP in dogs is the C-reactive protein (CRP). The dynamic of its concentration changes fast, rising and decreasing rapidly with the onset and removal of the inflammatory stimulus. It increases within the first 4–24 h after the stimulus and reaches up to a 50–100-fold increase of the baseline level. It has been documented that this APP’s concent

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Bobylev, Andrey A., S. A. Rachina, S. N. Avdeev, and A. A. Petrov. "Diagnostic, clinical and prognostic aspects determine the concentration of C-reactive protein in chronic heart failure." Clinical Medicine (Russian Journal) 96, no. 3 (2018): 197–207. http://dx.doi.org/10.18821/0023-2149-2018-96-3-197-207.

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A lot of mechanisms in development and progression of cardiac dysfunction are associated with changes of multiple markers and high-sensitivity C-reactive protein is one of them. The role of this inflammatory marker in heart failure pathogenesis requires further study. However, various recent reports have suggested that C-reactive protein assessment may be used for prediction of incident heart failure, its prognosis and estimation of the disease severity.

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Mouneshkumar, CD, Deepa, Saakshi Gulati, et al. "C-Reactive Protein Levels." Indian Journal of Dental Sciences 13, no. 3 (2021): 164–68. http://dx.doi.org/10.4103/ijds.ijds_137_20.

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Background: C-reactive protein (CRP) is a nonglycosylated pentameric polypeptide comprising 206 amino acid residues. CRP causes activation of the classical complement pathway by binding to various autologous and extrinsic ligands exposed on membranes of injured, necrotic, or cells undergoing apoptosis. There is evolving evidence which strongly suggests that CRP is an inflammatory marker and is significantly elevated in patients diagnosed with tumors such as hepatocellular, pulmonary, and breast carcinomas. In addition, serum CRP level has been shown to be associated with size of tumor (T), cli

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Edebiri O.E., Akpe C. I., Adewole A.S., et al. "Assessment of Inflammatory Markers (C - Reactive Protein and High Sensitivity C-Reactive Protein) in Preeclamptic Pregnant Women in the Third Trimester of Pregnancy." Green Health International Journal of Health Sciences Nursing and Nutrition 2, no. 1 (2025): 12–21. https://doi.org/10.70062/greenhealth.v2i1.145.

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C-reactive protein (CRP) and high-sensitivity C-reactive protein (hs-CRP) are general marker for inflammation and Arterial damage results from white blood cell invasion. This study aims to assess the level of inflammatory markers C-Reactive Protein (CRP) and High-Sensitivity C-Reactive Protein (hs-CRP) in preeclamptic pregnant women in the third trimester of pregnancy. Fourty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. Blood samples was spun in a bucket centrifuge at 2500 RPM (rounds per minute) for 10 minutes after which plasma was c

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Semple, SJ. "C-reactive protein - biological functions, cardiovascular disease and physical exercise." South African Journal of Sports Medicine 18, no. 1 (2006): 24. http://dx.doi.org/10.17159/2078-516x/2006/v18i1a249.

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C-reactive protein (CRP) is an acute-phase reactant that increases in response to noxious stimuli that inevitably induce cellular and/or tissue injury. The increased synthesis of CRP occurs predominantly in the liver and peaks 24 - 48 hours after the inciting stimulus. CRP forms an integral component of innate immunity and serves primarily to recognise potential pathogens and damaged cells. It facilitates the removal of these cells through opsonisation and activates the complement system. With increasing evidence supporting the classification of artherosclerosis as inflammatory in nature, CRP

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Devaraj, Sridevi, Uma Singh, and Ishwarlal Jialal. "The Evolving Role of C-Reactive Protein in Atherothrombosis." Clinical Chemistry 55, no. 2 (2009): 229–38. http://dx.doi.org/10.1373/clinchem.2008.108886.

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Abstract Background: Inflammation is pivotal in all phases of atherosclerosis. Among the numerous inflammatory biomarkers, the largest amount of published data supports a role for C-reactive protein (CRP) as a robust and independent risk marker in the prediction of primary and secondary adverse cardiovascular events. In addition to being a risk marker, there is much evidence indicating that CRP may indeed participate in atherogenesis. Content: In this review, we focus on the role of CRP in promoting atherothrombosis by discussing its effects on endothelial cells, endothelial progenitor cells,

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Wu, Yi, Lawrence A. Potempa, Driss El Kebir, and János G. Filep. "C-reactive protein and inflammation: conformational changes affect function." Biological Chemistry 396, no. 11 (2015): 1181–97. http://dx.doi.org/10.1515/hsz-2015-0149.

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Abstract The prototypic acute-phase reactant C-reactive protein (CRP) has long been recognized as a useful marker and gauge of inflammation. CRP also plays an important role in host defense against invading pathogens as well as in inflammation. CRP consists of five identical subunits arranged as a cyclic pentamer. CRP exists in at least two conformationally distinct forms, i.e. native pentameric CRP (pCRP) and modified/monomeric CRP (mCRP). These isoforms bind to distinct receptors and lipid rafts, and exhibit distinct functional properties. Dissociation of pCRP into its subunits occurs within

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Ignjatovic, Svetlana. "Determination of high sensitivity C-reactive protein: Clinical and analytical quality." Jugoslovenska medicinska biohemija 24, no. 2 (2005): 85–93. http://dx.doi.org/10.2298/jmh0502085i.

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Inflammation plays a key role in the pathophysiology of atherosclerotic disease. A number of inflammatory markers that are measurable in blood have been investigated for their ability to predict the risk of future atherosclerotic events. High-sensitivity (hs) measurement of C-reactive protein (CRP) has received a great deal of attention recently for use as an atherosclerotic risk marker. For these reasons, CRP is currently the inflammatory marker of choice. The Centers for Disease Control and Prevention (CCDC) and the American Heart Association (AHA) issued guidelines for the utility of this m

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I, Kadek Sumantara Artha, and Agung Ayu Ratih Dharmaiswari Anak. "The Correlation of Omega-3 Supplementation with CRP As Marker Inflammation in Autoimmune Diseases." International Journal of Medical Science and Clinical Research Studies 5, no. 05 (2025): 686–95. https://doi.org/10.5281/zenodo.15347928.

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Introduction: Omega-3 fatty acids are a type of polyunsaturated fatty acids (PUFAs) are regarded as anti-inflammatory lipids. The occurrence of diseases with an inflammatory aspect, including acute myocardial infarction, diabetes mellitus, autoimmune diseases such as multiple sclerosis (MS), rheumatoid arthritis (RA), psoriasis vulgaris, type 1 diabetes mellitus (T1DM), inflammatory bowel diseases (IBD) and systemic lupus erythematosus (SLE). Omega 3 can reduce inflammatory factor such as CRP (C- reactive protein) or hsCRP (High sensitive c-reactive protein). Objective: This systematic review

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Khairy, Ahmed, Hesham Fathey, Khaled Abddallah, and Ahmed Saber. "C - Reactive Protein Level as an Inflammatory Marker in Patients with Preeclampsia." Ain Shams Medical Journal 64, no. 1-3 (2013): 105–10. http://dx.doi.org/10.12816/0013826.

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Naureen, Tallat, Bushra Riaz, Aysha Mushtaq, Ehsan Shabbir, Muhammad Sohaib Nadeem, and Lubna Gohar. "SERUM C REACTIVE PROTEIN AS AN INFLAMMATORY MARKER IN GESTATIONAL DIABETES MELLITUS." Pakistan Journal of Physiology 19, no. 3 (2023): 3–6. http://dx.doi.org/10.69656/pjp.v19i3.1452.

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Background: Gestational diabetes mellitus is the most prevalent metabolic disorder of pregnancy. A number of factors are implicated in its causation. Inflammation may play a role in development of diabetes. This study aimed to look for an association between serum C reactive protein and gestational diabetes mellitus. Methods: This cross-sectional analytical study was carried out at Physiology Department, Army Medical College in collaboration with Pak Emirates Military Hospital from July 2019 to March 2020. Thirty healthy pregnant females and 30 gestational diabetes mellitus patients with 24–32

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Shin, Yun A., Kang Il Lim, and Min Hwa Suk. "Effect of Aerobic Exercise on C-Reactive Protein and Inflammatory Markers in Obese Women." Journal of Sport and Leisure Studies 30 (September 30, 2007): 571–81. http://dx.doi.org/10.51979/kssls.2007.09.30.571.

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Rathore, Vedika, Neelima Singh, Puneet Rastogi, Roshan Kumar Mahat, Mritunjay Kumar Mishra, and Reetika Shrivastava. "Lipid profile and its correlation with C-reactive protein in patients of acute myocardial infarction." International Journal of Research in Medical Sciences 5, no. 5 (2017): 2182. http://dx.doi.org/10.18203/2320-6012.ijrms20171866.

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Background: Acute myocardial infarction (AMI) is a significant cause of morbidity and mortality worldwide, which results from occlusion of coronary artery. Dyslipidemia is a major risk factor of AMI. C-reactive protein (CRP) is an acute phase protein, synthesized by hepatocytes in response to cytokines released into circulation by activated leukocytes and has been found to increase after AMI. The objective of the present study is to investigate lipid profile in AMI patients and correlate it with inflammatory marker i.e. CRP.Methods: The present study includes 150 AMI patients and 100 normal he

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Asegaonkar, Shilpa Balaji, Balaji Narayanrao Asegaonkar, Unmesh Vidyadhar Takalkar, Suresh Advani, and Anand Pandurang Thorat. "C-Reactive Protein and Breast Cancer: New Insights from Old Molecule." International Journal of Breast Cancer 2015 (2015): 1–6. http://dx.doi.org/10.1155/2015/145647.

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Recently an association between breast cancer and inflammation has emerged as the seventh hallmark of cancer. Chronic inflammation is a key contributor in the development and progression of carcinogenesis. Inflammatory pathways play an important role in the causation of breast cancer. C-reactive protein (CRP) an acute-phase reactant inflammatory protein is synthesized in hepatocytes in response to cytokines that are released from leucocytes within the tumor microenvironment. Several epidemiological studies appraised an association of CRP with breast cancer risk with inconsistent findings. Elev

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Datta, Subinay, Mrinal Pal, Amit Kumar Pradhan, et al. "Association of hsCRP and soluble fraction of E-selectin with diabetic and non-diabetic individuals." Journal of Advances in Internal Medicine 3, no. 1 (2014): 17–22. http://dx.doi.org/10.3126/jaim.v3i1.10697.

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doiBackground and aims: It is known that endothelial dysfunction and low-grade inflammation are important element of diabetic complications. The soluble E-selectin is a marker of endothelial dysfunction and C-reactive protein is the most important inflammatory marker. The present study is done to investigate the effect of diabetes on these two markers. Methods: The present hospital based case control study was conducted in the department of Biochemistry with the collaboration of department of Medicine of Burdwan Medical College, Burdwan, west Bengal India. All subjects were selected by simple

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Thiele, J. R., J. Zeller, H. Bannasch, G. B. Stark, K. Peter, and S. U. Eisenhardt. "Targeting C-Reactive Protein in Inflammatory Disease by Preventing Conformational Changes." Mediators of Inflammation 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/372432.

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C-reactive protein (CRP) is a pentraxin that has long been employed as a marker of inflammation in clinical practice. Recent findings brought up the idea of CRP to be not only a systemic marker but also a mediator of inflammation. New studies focused on structural changes of the plasma protein, revealing the existence of two distinct protein conformations associated with opposed inflammatory properties. Native, pentameric CRP (pCRP) is considered to be the circulating precursor form of monomeric CRP (mCRP) that has been identified to be strongly proinflammatory. Recently, a dissociation mechan

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Sonal, Agarwal. "Lymphocyte-to-C-reactive Protein (CRP) Ratio: A New Biomarker to Predict Perforation in Acute Appendicitis." International Journal of Pharmaceutical and Clinical Research 14, no. 11 (2022): 948–53. https://doi.org/10.5281/zenodo.13273339.

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<strong>Background: </strong>In Appendicitis is a frequent cause of abdominal pain worldwide. Around 18%- 34% of patients may present with perforations & risk of life. Various inflammatory markers have been evaluated in this regard one such is the Lymphocyte to C reactive protein ratio which has shown to be a promising inflammatory marker with high sensitivity & specificity in the differentiation of perforated & non-perforated appendicitis cases. <strong>Aims & Objectives:</strong> The study aimed to assess the role of the Lymphocyte to C reactive protein ratio i

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Sonawane, Shreya, Maindad Gayatri C. Gawade, Meghana K. Padwal, et al. "Novel Inflammatory Score: C-Reactive Protein/Albumin Ratio in Pancreatitis." International Journal of Pharmaceutical and Clinical Research 15, no. 3 (2023): 422–37. https://doi.org/10.5281/zenodo.12697623.

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<strong>Background and Objectives:</strong> To prevent the complications in pancreatitis, identification of the biomarker at an early stage for screening and prognosis is the need of time. CRP is an easily detectable positive acute-phase protein. A negative acute-phase protein albumin is an indicator of nutritional status. Both independently can be used as prognostic markers. Based on these, combining inflammation and nutritional status<em>, </em>the novel inflammatory prognostic score CAR (CRP/albumin ratio), can be studied in the pancreatitis patients. We planned this study to eval

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Geyer, Chiara E., Melissa Newling, Lathees Sritharan, et al. "C-Reactive Protein Controls IL-23 Production by Human Monocytes." International Journal of Molecular Sciences 22, no. 21 (2021): 11638. http://dx.doi.org/10.3390/ijms222111638.

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C-reactive protein (CRP) is an acute-phase protein in humans that is produced in high quantities by the liver upon infection and under inflammatory conditions. Although CRP is commonly used as a marker of inflammation, CRP can also directly contribute to inflammation by eliciting pro-inflammatory cytokine production by immune cells. Since CRP is highly elevated in serum under inflammatory conditions, we have studied the CRP-induced cytokine profile of human monocytes, one of the main innate immune cell populations in blood. We identified that CRP is relatively unique in its capacity to induce

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Çiçekli, Esen, and Dilcan Kotan. "C-reactive protein/albumin ratio as a prognostic biomarker in myasthenia gravis." Journal of Health Sciences and Medicine 8, no. 1 (2025): 126–31. https://doi.org/10.32322/jhsm.1600622.

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Aims: Limited research has explored novel inflammatory targets in myasthenia gravis (MG). This study aimed to investigate the role of the C-reactive protein (CRP)/albumin ratio (CAR) in disease activity and prognosis in MG patients. Methods: CRP, albumin, and CAR levels were compared between MG patients and healthy controls. The relationships of these parameters with MG activities of daily living (MG-ADL) scores and mortality were examined. Results: Sixty-six patients and 51 controls participated. CRP and CAR levels were significantly higher in the patient group (p=0.002, 0.003). No significan

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LINS, Daniel C., Josemberg M. CAMPOS, Patrícia S. de PAULA, et al. "C-REACTIVE PROTEIN IN DIABETIC PATIENTS BEFORE GASTRIC BYPASS AS A POSSIBLE MARKER FOR POSTOPERATIVE COMPLICATION." ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 28, suppl 1 (2015): 11–14. http://dx.doi.org/10.1590/s0102-6720201500s100005.

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Background : Obesity and type 2 diabetes mellitus are associated to inflammatory state, which can be set off by the adipose tissue, once it is a metabolically active organ that can cause a chronic mild inflammatory state. Aim : To evaluate the correlation between preoperative C-reactive protein and postoperative complications risk in obese patients (grades II and III) after Roux-en-Y gastric bypass, with and without type 2 diabetes mellitus. Methods : Between 2008 and 2013 were analysed 209 patients (107 with diabetes), presenting body mass index >40 kg/m2or >35 kg/m2with comorbidities.

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El-Awady, Saleh Ibrahim, Mohammed El-Nagar, Medhat El-Dakar, Mohammed Ragab, and Ghada Elnady. "Bacterial translocation in an experimental intestinal obstruction model: C-reactive protein reliability?" Acta Cirurgica Brasileira 24, no. 2 (2009): 98–106. http://dx.doi.org/10.1590/s0102-86502009000200005.

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BACKGROUND: Bacterial translocation occurs in preseptic conditions such as intestinal obstruction through unclear mechanism. The C-reactive protein is an acute phase reactant and a marker of ischemia. METHODS: 45 albino male rats were divided into 3 groups each 15 rats. GI control, GII simple intestinal-obstruction and GIII strangulated obstruction. Outcome measures were: (1) Bacteriologic count and typing for intestinal contents, intestinal wall, liver, mesenteric lymph nodes and blood (cardiac and portal) (2) Histopathologic: mucosal injury score, inflammatory cell infiltrate in the wall, ML

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Cici Nuriah, Febriana Catur Iswanti, and Ariel Pradipta. "The Role of High Sensitivity C-Reactive Protein as an Inflammation Predictor in Cardiovascular Diseases." Bioscientia Medicina : Journal of Biomedicine and Translational Research 8, no. 9 (2024): 4965–76. http://dx.doi.org/10.37275/bsm.v8i9.1075.

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Inflammation can be measured by analyzing the levels of inflammatory markers, such as High Sensitivity C-reactive Protein (hs-CRP). This protein plays a crucial role as a strong independent predictor indicating the risk of cardiovascular. The hs-CRP can measure the levels of C-reactive protein with high sensitivity, making it a highly responsive marker to acute-phase inflammation. The presence of hs-CRP serves as an inflammation indicator that can predict the potential occurrence of heart attacks, strokes, peripheral artery diseases, and sudden death due to Acute Coronary Syndrome (ACS). Produ

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González, Gisella Rojas, and Sandra Silva De la Fuente. "Is C-Reactive Protein an Indicator of Periodontal Risk?" Clinical Neuroscience Research 1, no. 1 (2023): 7–14. http://dx.doi.org/10.26689/cnr.v1i1.4032.

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Periodontitis is a chronic, multifactorial, inflammatory disease caused by microorganisms and characterized by the progressive destruction of tooth-supporting tissue. In recent years, studies have shown a correlation and association between periodontitis and atherosclerotic cardiovascular disease, because both the disease has some similar risk factors and they produce an increase in plasma C-reactive protein (CRP) level. This protein has been attributed favorable characteristics as an inflammatory marker. This study was aimed to identify if there is any relationship between periodontitis and C

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Dodo, Saputera Damian, Arief Erwin, Bakri Syakib, et al. "Correlation between C-reactive protein concentration with disease severity in new case pulmonary tuberculosis with positive smear patients in Makassar." International Journal of Medical Reviews and Case Reports 3, no. 11 (2019): 693–96. https://doi.org/10.5455/IJMRCR.pulmonary-tuberculosis.

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Background: Tuberculosis is an infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis.[1] C-reactive protein is acute phase reactants that increase during inflammatory process occurs in the body. Mycobacterium tuberculosis enters body, causes inflammation and releases various pro-inflammatory cytokines, mainly interleukin 8 and interleukin 6.[2] Increased plasma concentration of interleukin 6 stimulates increased C-reactive protein synthesis by hepatocyte cells in the liver.[4] Objective: Determined the correlation between C-reactive protein levels wit

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Helniasari, Helniasari, Nurhidayanti Nurhidayanti, and Bastian Bastian. "Perbedaan Kadar C-Reaktive Protein (CRP) Pada Sampel Serum dan Plasma K3EDTA Dengan Metode Imunoturbidimetri." JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST 5, no. 2 (2022): 139. http://dx.doi.org/10.30651/jmlt.v5i2.13350.

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Examination of levels of C-Reactive Protein (CRP) in the blood is one of the tests. that can detect inflammation at an early stage. C-Reactive Protein (CRP) is an inflammatory marker that is synthesized in the liver. CRP levels increase due to trauma, bacterial infection and inflammation (inflammation and tissue damage). CRP is synthesized by the liver and It released into the bloodstream for 6-10 hours after the acute inflammatory process and acute destruction. Tissue detection CRP is also one of several proteins often referred to as the acute phase and It is used to monitor changes in the ac

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Bhandari, Peter, Reanay Berezovskiy, Salima Makhani, Valerie Gausman, Neelesh Rastogi, and Sabina Braude. "Discordance in Clinical Indicators With Sequential Fecal Microbiota Transplantation: A Case of Fulminant Clostridioides Difficile Infection." ACG Case Reports Journal 12, no. 6 (2025): e01731. https://doi.org/10.14309/crj.0000000000001731.

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ABSTRACT Fulminant Clostridioides difficile infection (CDI) is a rare, severe type of CDI, often associated with extended hospitalizations, significant healthcare costs, and elevated mortality rates. Fecal microbiota transplantation remains an effective treatment modality for patients with fulminant CDI, with high cure rates reported after multiple treatments. Stool frequency, pseudomembrane resolution, and inflammatory markers are routinely monitored to evaluate disease severity and treatment responsiveness. Our case highlights a discordance in these indicators and demonstrates C-reactive pro

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Nykytyuk, S. O., S. I. Klumnyuk, S. S. Levenets, and T. О. Vorontsova. "C-REACTIVE PROTEIN AS A BIOCHEMICAL CRITERION OF A GENERAL INFLAMMATORY SYNDROME IN LYME DISEASE IN CHILDREN." Актуальні питання педіатрії, акушерства та гінекології, no. 1 (October 19, 2022): 52–56. http://dx.doi.org/10.11603/24116-4944.2022.1.13251.

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The aim of the study – to improve the methods of non-specific biochemical markers of Lyme disease. Materials and Methods. A group of children (62) aged from 1 to 14 years was observed for the identification of pathogens of blood-borne infections among children. C-reactive protein (CRP) is a protein and acute phase reagent as well as the information base for the interpretation and analysis of clinical observations of CRP. Results and Discussion. There were studied the concentrations of acute-phase response proteins including CRP in children with Lyme disease. We found that circulati

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Vermeire, Séverine, Gert Van Assche, and Paul Rutgeerts. "The role of C-reactive protein as an inflammatory marker in gastrointestinal diseases." Nature Clinical Practice Gastroenterology & Hepatology 2, no. 12 (2005): 580–86. http://dx.doi.org/10.1038/ncpgasthep0359.

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Kim, Yoonseo, Nicole Noren Hooten, Douglas F. Dluzen, Jennifer L. Martindale, Myriam Gorospe, and Michele K. Evans. "Posttranscriptional Regulation of the Inflammatory Marker C-Reactive Protein by the RNA-Binding Protein HuR and MicroRNA 637." Molecular and Cellular Biology 35, no. 24 (2015): 4212–21. http://dx.doi.org/10.1128/mcb.00645-15.

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C-reactive protein (CRP), an acute-phase plasma protein, is a major component of inflammatory reactions functioning as a mediator of innate immunity. It has been widely used as a validated clinical biomarker of the inflammatory state in trauma, infection, and age-associated chronic diseases, including cancer and cardiovascular disease (CVD). Despite this, the molecular mechanisms that regulate CRP expression are not well understood. Given that theCRP3′ untranslated region (UTR) is long and AU rich, we hypothesized that CRP may be regulated posttranscriptionally by RNA-binding proteins (RBPs) a

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TAKALA, Annika, Irma JOUSELA, Klaus T. OLKKOLA, et al. "Systemic inflammatory response syndrome without systemic inflammation in acutely ill patients admitted to hospital in a medical emergency." Clinical Science 96, no. 3 (1999): 287–95. http://dx.doi.org/10.1042/cs0960287.

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Criteria of the systemic inflammatory response syndrome (SIRS) are known to include patients without systemic inflammation. Our aim was to explore additional markers of inflammation that would distinguish SIRS patients with systemic inflammation from patients without inflammation. The study included 100 acutely ill patients with SIRS. Peripheral blood neutrophil and monocyte CD11b expression, serum interleukin-6, interleukin-1β, tumour necrosis factor-α and C-reactive protein were determined, and severity of inflammation was evaluated by systemic inflammation composite score based on CD11b exp

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Alieva, Amina M., Natalia V. Teplova, Maxim A. Batov, et al. "Pentraxin-3 – a promising biological marker in heart failure: literature review." Consilium Medicum 24, no. 1 (2022): 53–59. http://dx.doi.org/10.26442/20751753.2022.1.201382.

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According to many studies, inflammation plays a very significant role in the pathogenesis of heart failure. Many studies have demonstrated an increase in circulating levels of inflammatory markers and cytokines such as C-reactive protein, tumor necrosis factor-a (TNF-a), and interleukins. C-reactive protein is produced in the liver in response to stimulation by various cytokines, mainly interleukin-6, and is a member of the pentraxin superfamily. Pentraxin-3, which is a long pentraxin, has a C-terminal domain of pentraxin similar to the classic short pentraxins, but differs from them in the pr

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Ahmed, Mohsin, Md Mesbahul Islam, AKM Monwarul Islam, et al. "Association of Obesity and C-Reactive Protein with Coronary Artery Disease." Bangladesh Heart Journal 36, no. 1 (2021): 9–16. http://dx.doi.org/10.3329/bhj.v36i1.55512.

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Background: Obesity is now becoming a global epidemic. It is most of the times associated with hypertension, diabetes mellitus (DM), metabolic syndrome and dyslipidemia which are known risk factors for coronary artery disease (CAD). Coronary arteriosclerosis comprises a series of inflammatory responses at cellular and molecular level, whose reactions are stronger in obese patients. The objective of this study was to observe the association of obesity and raised inflammatory markers with CAD. Method: This cross-sectional study was carried out in the Department of Cardiology, Dhaka Medical Colle

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Ali, Sarah, Aiza Zehra, Muhammad Umair Khalid, Momina Hassan, and Syed Imran Ali Shah. "Role of C-reactive protein in disease progression, diagnosis and management." Discoveries 11, no. 4 (2023): e179. https://doi.org/10.15190/d.2023.18.

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C-reactive protein (CRP) is a ring-shaped pentameric protein synthesized in the liver via CRP gene transcription. It is an inflammatory marker, whose serum levels can be measured using traditional and high-sensitivity tests. In healthy adults, the normal CRP serum concentrations vary between 0.8 mg/L and 3.0 mg/L. These can be grouped into low-, moderate-, and high-risk categories according to CRP levels of less than 1, 1-3, and greater than 3 mg/L, respectively. Elevated levels have been observed in infections, autoimmune diseases, neurodegenerative disorders, and malignancies. However, it is

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Askin, Lutfu, Okan Tanriverdi, Hakan Tibilli, and Serdar Turkmen. "Prognostic value of C-reactive protein/albumin ratio in ST-segment elevation myocardial infarction." Interventional Medicine and Applied Science 11, no. 3 (2020): 168–71. http://dx.doi.org/10.1556/1646.11.2019.20.

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Serum C-reactive protein (CRP)/albumin ratio (CAR) is demonstrated as a more precise marker in determining the prognosis of critical diseases than albumin and CRP levels, separately. Recently, inflammatory biomarkers are increasingly used for both screening and prognosis of coronary artery disease (CAD). As an ischemia-dependent risk index, CAR is an independent marker of in-hospital and long-term all-cause mortality in ST-segment elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention. The results indicate that CAR is a more effective prognostic marker than eit

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Gambi, F., D. De Berardis, D. Campanella, et al. "A Retrospective Evaluation of the Inflammatory Marker C-Reactive Protein (CRP), Cholesterol and High-Density Lipoproteins in Patients with Major Depression: Preliminary Findings." European Journal of Inflammation 3, no. 3 (2005): 127–34. http://dx.doi.org/10.1177/1721727x0500300304.

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The aim of this study was to retrospectively evaluate the role of C-reactive protein, total cholesterol and high-density lipoprotein cholesterol in patients suffering from Major Depression (MD). Data of C-reactive protein, total cholesterol (TC) and high-density lipoprotein cholesterol of 37 adult outpatients (17 men, 20 women) with a DSM-IV diagnosis of MD were analyzed. Depression was measured with the 17-item Hamilton Depression Rating Scale (HAM-D) and with the Beck Depression Inventory (BDI). Suicide risk was evaluated with the Scale of Suicide Ideation (SSI). Patients with a lifetime his

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Gursu, M., S. Ozturk, Z. Aydin, et al. "Is Pentraxin-3 Stronger Than C-Reactive Protein to Determine Inflammation in Peritoneal Dialysis Patients?" European Journal of Inflammation 10, no. 3 (2012): 289–95. http://dx.doi.org/10.1177/1721727x1201000305.

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Pentraxin-3 (PTX-3) is the prototype of long pentraxins and is produced by many tissues and organs including vascular endothelial cells in response to pro-inflammatory signals. It is thought to be an independent indicator of disease activity. We analyzed the correlation of PTX-3 with other markers of inflammation in peritoneal dialysis (PD) patients. Non-diabetic patients on chronic PD program who meet the dialysis adequacy criteria and who had no active infectious/inflammatory disease were included. Demographic and clinical parameters were recorded as well as hsCRP, fibrinogen, interleukin-6

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Dyer, Emma M., Thomas Waterfield, and Hannah Baynes. "How to use C-reactive protein." Archives of disease in childhood - Education & practice edition 104, no. 3 (2018): 150–53. http://dx.doi.org/10.1136/archdischild-2018-315079.

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A 3-month-old baby is brought to the paediatric emergency department by their parents because of a fever. You decide to check their inflammatory markers. Their C-reactive protein (CRP) level comes back as 20 mg/L. Does this affect whether or not you start antibiotic therapy? Does it influence your decision to admit or discharge the patient? CRP is a commonly used biochemical test and yet its use is constantly debated and challenged. We look at the current evidence and suggest the best way to use this test in clinical practice.

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Mohylnyk, A., K. Tarasenko, Ye Sonnik, A. Davydenko, and O. Arkhipovets. "C-REACTIVE PROTEIN TO PLASMA ALBUMIN RATIO AS A PROGNOSTIC INDICATOR IN INTENSIVE CARE UNIT PATIENTS." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 25, no. 2 (2025): 269–73. https://doi.org/10.31718/2077-1096.25.2.269.

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Relevance. Polytrauma represents a serious interdisciplinary medical challenge and is one of the leading causes of mortality, particularly in a country engaged in active warfare. C-reactive protein is an acute-phase reactant whose plasma concentration reflects cytokine-induced inflammatory activity. Albumin, synthesized by the liver, constitutes the major portion of total plasma protein and serves as a marker of nutritional status. It maintains intravascular oncotic pressure, supports circulating blood volume, and plays an essential role in metabolite transport. Objective. To evaluate the prog

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Nakayama, T., S. Sonoda, T. Urano, T. Yamada, and M. Okada. "Monitoring both serum amyloid protein A and C-reactive protein as inflammatory markers in infectious diseases." Clinical Chemistry 39, no. 2 (1993): 293–97. http://dx.doi.org/10.1093/clinchem/39.2.293.

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Abstract We examined serum amyloid protein A (SAA) and C-reactive protein (CRP) as inflammatory markers of viral and bacterial infections. Both acute-phase reactants increased in the acute stage and thereafter decreased in the convalescent stage. In viral infections, the mean serum concentrations of SAA during the acute stage were 141 mg/L in infections with adenovirus, 77 mg/L with measles virus, 63 mg/L with influenza virus, 55 mg/L with parainfluenza virus, 31 mg/L with respiratory syncytial virus, and 31 mg/L in aseptic meningitis. The mean serum concentration of CRP was 19 mg/L for adenov

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Daniel, H. Kriz, and Hansson Lars-Olof. "Development of a Low-Cost Arduino Based Laser Nephelometric Instrumentation for High Sensitivity determination of the Inflammatory Marker C-Reactive Protein (CRP)." International Journal of Engineering Research & Science 4, no. 6 (2018): 51–55. https://doi.org/10.5281/zenodo.1302319.

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<strong><em>Abstract</em></strong><strong>—</strong> <em>A simple low-cost (<60 USD) Arduino based laser nephelometric instrument, which is suitable for high sensitive immunoprecipitation detection is presented. A measuring range of up to 49 mg/L of dog C-Reactive Protein (CRP) is reported. Furthermore, the limit of detection (LOD) is determined to be 2.1 mg/L. Only 24 µL of dog serum samples are required. Assay-time is 6 minutes. We successfully demonstrated the good performance of the device on two low level (0 and 10.2 mg/L CRP) dog serum samples. The coefficient of variation

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Berkley, Annie, and Albert Ferro. "Changes in C-reactive protein in response to anti-inflammatory therapy as a predictor of cardiovascular outcomes: A systematic review and meta-analysis." JRSM Cardiovascular Disease 9 (January 2020): 204800402092923. http://dx.doi.org/10.1177/2048004020929235.

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Background Despite the availability of aggressive lipid-lowering strategies, many patients remain at risk of cardiovascular events. C-reactive protein is a marker of inflammation elevated in patients at high risk of cardiovascular events. C-reactive protein has demonstrated value as a predictor of cardiovascular risk; however, it is unclear whether targeting C-reactive protein levels improves outcomes. This systematic review aimed to characterise the relationship between C-reactive protein and cardiovascular outcomes and to assess whether the magnitude of C-reactive protein reduction correlate

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