Academic literature on the topic 'Caco2 and HaCaT'

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Journal articles on the topic "Caco2 and HaCaT"

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Lin, Kuen-Tze, Tsu-Chung Chang, Feng-Yi Lai, Chun-Shu Lin, Hsing-Lung Chao та Shih-Yu Lee. "Rhodiola crenulata Attenuates γ-Ray Induced Cellular Injury via Modulation of Oxidative Stress in Human Skin Cells". American Journal of Chinese Medicine 46, № 01 (2018): 175–90. http://dx.doi.org/10.1142/s0192415x18500106.

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Skin injury is a major complication during radiation therapy and is associated with oxidative damage to skin cells. An effective and safe radioprotectant to prevent this skin damage is still unavailable. The Rhodiola crenulata root extract (RCE) has been reported to be a free radical scavenger and a potent anti-oxidant in both in vitro and in vivo models. In the current study, we investigated the effects of RCE on ionizing radiation-induced skin injury and its underlying mechanisms. HaCaT cells — a non-cancerous skin cell line together with HepG2, Caco2, A549, and OECM cancer cell lines — were
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Mitropoulou, Gregoria, Marianthi Sidira, Myria Skitsa, et al. "Assessment of the Antimicrobial, Antioxidant, and Antiproliferative Potential of Sideritis raeseri subps. raeseri Essential Oil." Foods 9, no. 7 (2020): 860. http://dx.doi.org/10.3390/foods9070860.

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The aim of the present study was to investigate the antimicrobial potential of Sideritis raeseri subps. raeseri essential oil (EO) against common food spoilage and pathogenic microorganisms and evaluate its antioxidant and antiproliferative activity. The EO was isolated by steam distillation and analyzed by GC/MS. The main constituents identified were geranyl-p-cymene (25.08%), geranyl-γ-terpinene (15.17%), and geranyl-linalool (14.04%). Initially, its activity against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Listeria monocytogenes, Salmonella Enteritidis, Salmonell
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Lishchynskyi, Ostap, Yurij Stetsyshyn, Joanna Raczkowska, et al. "Fabrication and Impact of Fouling-Reducing Temperature-Responsive POEGMA Coatings with Embedded CaCO3 Nanoparticles on Different Cell Lines." Materials 14, no. 6 (2021): 1417. http://dx.doi.org/10.3390/ma14061417.

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In the present work, we have successfully prepared and characterized novel nanocomposite material exhibiting temperature-dependent surface wettability changes, based on grafted brush coatings of non-fouling poly(di(ethylene glycol)methyl ether methacrylate) (POEGMA) with the embedded CaCO3 nanoparticles. Grafted polymer brushes attached to the glass surface were prepared in a three-step process using atom transfer radical polymerization (ATRP). Subsequently, uniform CaCO3 nanoparticles (NPs) embedded in POEGMA-grafted brush coatings were synthesized using biomineralized precipitation from solu
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Barndt, Robert B., Mon-Juan Lee, Nanxi Huang, et al. "Targeted HAI-2 deletion causes excessive proteolysis with prolonged active prostasin and depletion of HAI-1 monomer in intestinal but not epidermal epithelial cells." Human Molecular Genetics 30, no. 19 (2021): 1833–50. http://dx.doi.org/10.1093/hmg/ddab150.

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Abstract Mutations of SPINT2, the gene encoding the integral membrane, Kunitz-type serine inhibitor HAI-2, primarily affect the intestine, while sparing many other HAI-2-expressing tissues, causing sodium loss in patients with syndromic congenital sodium diarrhea. The membrane-bound serine protease prostasin was previously identified as a HAI-2 target protease in intestinal tissues but not in the skin. In both tissues, the highly related inhibitor HAI-1 is, however, the default inhibitor for prostasin and the type 2 transmembrane serine protease matriptase. This cell-type selective functional
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Gandamalla, Durgaiah, Harikiran Lingabathula, and Narsimha Reddy Yellu. "CYTOTOXICITY EVALUATION OF TITANIUM AND ZINC OXIDE NANOPARTICLES ON HUMAN CELL LINES." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 10 (2017): 240. http://dx.doi.org/10.22159/ijpps.2017v9i11.21924.

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Objective: In vitro cytotoxicity evaluation of titanium dioxide, 20 nm (TNP 20) and zinc oxide, 20 nm (ZNP 20) nanoparticles (NP) were tested on different types of human skin (HaCat), lung (A549), liver (Hep G2) and colon (Caco-2) cell cultures in relevance to human risk assessmentMethods: The different concentrations of test TNP 20 and ZNP 20 1-300 µg/ml were exposed to determine the cell viability reduction on four human cell lines after 48 h post exposure using 3-(4, 5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT). The mitochondrial membrane activities of the viable cells we
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Andreani, Tatiana, Verónica Nogueira, Ana Gavina, et al. "Ecotoxicity to Freshwater Organisms and Cytotoxicity of Nanomaterials: Are We Generating Sufficient Data for Their Risk Assessment?" Nanomaterials 11, no. 1 (2020): 66. http://dx.doi.org/10.3390/nano11010066.

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The aim of the present study was to investigate the eco-cytotoxicity of several forms of nanomaterials (NM), such as nano-CuO, nano-TiO2, nano-SiO2 and nano-ZnO, on different aquatic species (Raphidocelis subcapitata, Daphnia magna and Lemna minor) following standard protocols and on human cell lines (Caco-2, SV-80, HepG2 and HaCaT). Predicted no-effect concentrations (PNEC) or hazard concentrations for 5% of the species (HC5) were also estimated based on the compilation of data available in the literature. Most of the NM agglomerated strongly in the selected culture media. For the ecotoxicity
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Almutary, Abdulmajeed G., and Barbara J. S. Sanderson. "Toxicity of N-Nitrosodimethylamine and SiO2 nanoparticles to HaCaT and caco-2 cell lines found in waste water treatment." Journal of Toxicology and Health 4, no. 1 (2017): 4. http://dx.doi.org/10.7243/2056-3779-4-4.

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Dursun, Feyza Nur, and Erdinc Bal. "Hasat Sonrası Bazı Uygulamaların Autumn Giant Erik Çeşidinin Muhafaza Performansı Üzerine Etkisi." Turkish Journal of Agriculture - Food Science and Technology 8, no. 2 (2020): 504. http://dx.doi.org/10.24925/turjaf.v8i2.504-510.3070.

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In this study, the effect of postharvest salicylic acid (2 mM), oxalic acid (5 mM), putrescine (2 mM) and calcium (4% CaCl2) applications on storage performance of Autumn Giant plum fruit were investigated. After applications, plum fruits were placed in modified atmosphere packaging (MAP) and stored for 40 days at 85-90% relative humidity conditions at 0.5±0.5°C. In order to determine the fruit quality characteristics after treatments, weight loss, soluble solids content, titratable acidity, fruit firmness, ascorbic acid, total flavonoids, total phenolics and total antioxidant content analysis
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Luckanagul, Jittima Amie, Pahweenvaj Ratnatilaka Na Bhuket, Chawanphat Muangnoi, Pranee Rojsitthisak, Qian Wang, and Pornchai Rojsitthisak. "Self-Assembled Thermoresponsive Nanogel from Grafted Hyaluronic Acid as a Biocompatible Delivery Platform for Curcumin with Enhanced Drug Loading and Biological Activities." Polymers 13, no. 2 (2021): 194. http://dx.doi.org/10.3390/polym13020194.

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A hyaluronic acid-grafted poly(N-isopropylacrylamide) (HA-pNIPAM) was synthesized as a polymeric nanogel platform for encapsulation and delivery of hydrophobic bioactive compounds using curcumin as a model drug. As demonstrated by transmission electron microscopy and dynamic light scattering techniques, the HA-pNIPAM was simply assembled into spherical nano-sized particles with the thermoresponsive behavior. The success of curcumin aqueous solubilization was confirmed by fluorescent spectroscopy. The resulting nanogel formulation enhanced the aqueous solubility and uptake into NIH-3T3 cells of
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Luckanagul, Jittima Amie, Pahweenvaj Ratnatilaka Na Bhuket, Chawanphat Muangnoi, Pranee Rojsitthisak, Qian Wang, and Pornchai Rojsitthisak. "Self-Assembled Thermoresponsive Nanogel from Grafted Hyaluronic Acid as a Biocompatible Delivery Platform for Curcumin with Enhanced Drug Loading and Biological Activities." Polymers 13, no. 2 (2021): 194. http://dx.doi.org/10.3390/polym13020194.

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A hyaluronic acid-grafted poly(N-isopropylacrylamide) (HA-pNIPAM) was synthesized as a polymeric nanogel platform for encapsulation and delivery of hydrophobic bioactive compounds using curcumin as a model drug. As demonstrated by transmission electron microscopy and dynamic light scattering techniques, the HA-pNIPAM was simply assembled into spherical nano-sized particles with the thermoresponsive behavior. The success of curcumin aqueous solubilization was confirmed by fluorescent spectroscopy. The resulting nanogel formulation enhanced the aqueous solubility and uptake into NIH-3T3 cells of
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Dissertations / Theses on the topic "Caco2 and HaCaT"

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Ebabe, Elle Etienne Raymond. "Le double aspect des nanoparticules manufacturées sur les métabolismes oxydatifs et inflammatoires : effets délétères et effets protecteurs." Thesis, Montpellier, 2016. http://www.theses.fr/2016MONTT008/document.

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On étudie les effets des nanoparticules (d'argent et de silice) manufacturées sur les métabolismes oxydatifs et inflammatoire. La première partie étudie la toxicité in vivo de l'ingestion de nanoparticules d'argent, pendant 11 semaines, sur un modèle animal - rat Sprague Dawley. Nous y avons mis en évidence l'action toxique des nanoparticules d'argent notamment une hausse de la production d'anion superoxyde par les NADPH oxydases hépatiques et cardiaques, des dyslipidémies, une cytolyse hépatique, une augmentation de cytokines pro-inflammatoires et une tendance à la baisse de l'activité d'enzy
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Siopa, João Rafael Rodrigues. "Mecanismos celulares subjacentes à potencial ação fotodinâmica induzida por corantes cianínicos esquarílicos." Master's thesis, 2017. http://hdl.handle.net/10348/8060.

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Dissertação de Mestrado em Bioquímica<br>A terapia fotodinâmica (PDT - do Inglês Photodynamic Therapy) é uma técnica terapêutica baseada numa reação fotoquímica que conjuga uma molécula fotossensibilizadora, oxigénio molecular e luz, sendo usada em tratamentos de várias doenças, não só como em alguns tipos de cancros, mas também de lesões não-malignas. Foi introduzida no século XX e, consiste na administração de um agente fotossensibilizador (FS) que, quando irradiado a comprimentos de onda e intensidades adequadas, é ativado e produz espécies citotóxicas capazes de destruir o tecido afetado.
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