Academic literature on the topic 'Caffeic acid phenethyl ester (CAPE)'

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Journal articles on the topic "Caffeic acid phenethyl ester (CAPE)"

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Petelinc, Tanja, Manca Medved, Tomaž Polak, and Polona Jamnik. "Caffeic Acid Esters Affect Intracellular Oxidation and Vitality of Yeast Saccharomyces cerevisiae Cells." Natural Product Communications 12, no. 11 (2017): 1934578X1701201. http://dx.doi.org/10.1177/1934578x1701201131.

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The effect of four esters of caffeic acid, caffeic acid methanol ester (CAME), caffeic acid ethanol ester (CAEE), caffeic acid isopropyl ester (CAIPE) and caffeic acid phenethyl ester (CAPE) on intracellular oxidation, vitality and viability of the yeast Saccharomyces cerevisiae as a model eukaryotic organism was investigated. Results showed that each ester showed its own behavior at the concentrations tested. For CAPE, CAIPE and CAEE decreased intracellular oxidation and simultaneously increased cellular vitality with no changes in cellular viability compared to the control were determined. A
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Kassim, Mustafa, Marzida Mansor, Tengku Ain Kamalden, et al. "Caffeic Acid Phenethyl Ester (CAPE)." Shock 42, no. 2 (2014): 154–60. http://dx.doi.org/10.1097/shk.0000000000000179.

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Kong, Lingjie, Yuhao Zhang, Zhouxu Feng, Jie Dong, and Hongcheng Zhang. "Phenolic Compounds of Propolis Alleviate Lipid Metabolism Disorder." Evidence-Based Complementary and Alternative Medicine 2021 (February 20, 2021): 1–16. http://dx.doi.org/10.1155/2021/7615830.

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Lipid metabolism disorder is one of the significant risk factors for a multitude of human diseases and has become a serious threat to human health. The present study aimed to evaluate the effects of phenolics from poplar-type propolis on regulating lipid metabolism by using cell models of steatosis induced by palmitic acid (PA). Our study shows that phenolic esters have higher lipid-lowering activities than phenolic acids, especially for three caffeic acid esters, including caffeic acid phenethyl ester (CAPE), caffeic acid cinnamyl ester (CACE), and caffeic acid benzyl ester (CABE). Most notab
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Collins, William, Noah Lowen, and David J. Blake. "Caffeic Acid Esters Are Effective Bactericidal Compounds Against Paenibacillus larvae by Altering Intracellular Oxidant and Antioxidant Levels." Biomolecules 9, no. 8 (2019): 312. http://dx.doi.org/10.3390/biom9080312.

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American Foulbrood (AFB) is a deadly bacterial disease affecting pupal and larval honey bees. AFB is caused by the endospore-forming bacterium Paenibacillus larvae (PL). Propolis, which contains a variety of organic compounds, is a product of bee foraging and is a resinous substance derived from botanical substances found primarily in trees. Several compounds from the class of caffeic acid esters, which are commonly found in propolis, have been shown to have antibacterial activity against PL. In this study, six different caffeic acid esters were synthesized, purified, spectroscopically analyze
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Murtaza, Ghulam, Sabiha Karim, Muhammad Rouf Akram, et al. "Caffeic Acid Phenethyl Ester and Therapeutic Potentials." BioMed Research International 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/145342.

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Caffeic acid phenethyl ester (CAPE) is a bioactive compound of propolis extract. The literature search elaborates that CAPE possesses antimicrobial, antioxidant, anti-inflammatory, and cytotoxic properties. The principal objective of this review article is to sum up and critically assess the existing data about therapeutic effects of CAPE in different disorders. The findings elaborate that CAPE is a versatile therapeutically active polyphenol and an effective adjuvant of chemotherapy for enhancing therapeutic efficacy and diminishing chemotherapy-induced toxicities.
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Olgierd, Batoryna, Żyła Kamila, Banyś Anna, and Morawiec Emilia. "The Pluripotent Activities of Caffeic Acid Phenethyl Ester." Molecules 26, no. 5 (2021): 1335. http://dx.doi.org/10.3390/molecules26051335.

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Caffeic acid phenethyl ester (CAPE) is a strong antioxidant extracted from honey bee-hive propolis. The mentioned compound, a well-known NF-κB inhibitor, has been used in traditional medicine as a potent anti-inflammatory agent. CAPE has a broad spectrum of biological properties including anti-viral, anti-bacterial, anti-cancer, immunomodulatory, and wound-healing activities. This review characterizes published data about CAPE biological properties and potential therapeutic applications, that can be used in various diseases.
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Pittalà, Valeria, Loredana Salerno, Giuseppe Romeo, Rosaria Acquaviva, Claudia Di Giacomo, and Valeria Sorrenti. "Therapeutic Potential of Caffeic Acid Phenethyl Ester (CAPE) in Diabetes." Current Medicinal Chemistry 25, no. 37 (2019): 4827–36. http://dx.doi.org/10.2174/0929867324666161118120908.

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Diabetes mellitus is a complex metabolic disease characterized by high blood sugar levels. Different pathogenic processes are involved in the etiology of the disease. Indeed, chronic diabetes hyperglycemia is often associated with severe long-term complications including cardiovascular symptoms, retinopathy, nephropathy, and neuropathy. Although the precise molecular mechanisms underlying diabetes are not yet clear, it is widely accepted that increased levels of oxidative stress are involved in the onset, development and progression of diabetes and its related complications. In this regard, th
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Tekin, Ahmet, Serdar Türkyılmaz, Tevfik Küçükkartallar, et al. "Effects of Caffeic Acid Phenethyl Ester (CAPE) on Hepatopulmonary Syndrome." Inflammation 34, no. 6 (2010): 614–19. http://dx.doi.org/10.1007/s10753-010-9270-8.

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Ağrı, İbrahim, Arzu Erdal Ağrı, Mehmet Eser Sancaktar, et al. "The effect of caffeic acid phenethyl ester (CAPE) on tympanosclerosis." International Journal of Pediatric Otorhinolaryngology 95 (April 2017): 127–32. http://dx.doi.org/10.1016/j.ijporl.2017.02.020.

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Anjaly, Km, and Ashu B. Tiku. "Radio-Modulatory Potential of Caffeic Acid Phenethyl Ester: A Therapeutic Perspective." Anti-Cancer Agents in Medicinal Chemistry 18, no. 4 (2018): 468–75. http://dx.doi.org/10.2174/1871520617666171113143945.

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Background: Use of natural agents is an upcoming area of research in cancer biology. Caffeic acid phenethyl ester (CAPE) has received great attention because of its therapeutic potential in various conditions including cancer. It is an active/abundant component of propolis, a honey bee hive product produced by bees using their enzyme-rich digestive secretions on resinous mix, bee wax and pollen from plants. It is used to protect the beehive against bacteria and other infections. Therefore a literature survey was done to understand the therapeutic potential of this compound. Although a lot of w
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Dissertations / Theses on the topic "Caffeic acid phenethyl ester (CAPE)"

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Roso, Nilson de Camargos [UNESP]. "Estudo da proteção renal durante a isquemia e reperfusão em ratos com o CAPE (caffeic acid phenethyl ester)." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/100142.

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Made available in DSpace on 2014-06-11T19:30:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-08-19Bitstream added on 2014-06-13T19:19:21Z : No. of bitstreams: 1 roso_nc_dr_botfm.pdf: 1975320 bytes, checksum: 9363a3fa3f08654c7f41e33f7fc538a8 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>o CAPE, ativo componente da própolis, é um potente antioxidante com importantes ações no estudo da isquemia e reperfusão renal. O objetivo deste estudo é avaliar o efeito do CAPE na lesão renal de isquemia-reperfusão em ratos anestesiados com isoflurano. Utilizou-se
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Roso, Nilson de Camargos. "Estudo da proteção renal durante a isquemia e reperfusão em ratos com o CAPE (caffeic acid phenethyl ester) /." Botucatu : [s.n.], 2011. http://hdl.handle.net/11449/100142.

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Orientador: Pedro Thadeu Galvão Vianna<br>Banca: Luiz Antonio Vane<br>Banca: João Abrão<br>Banca: Antonio Carlos Aguiar Brandão<br>Banca: Flora Margarida Barra Bisinotto<br>Resumo: o CAPE, ativo componente da própolis, é um potente antioxidante com importantes ações no estudo da isquemia e reperfusão renal. O objetivo deste estudo é avaliar o efeito do CAPE na lesão renal de isquemia-reperfusão em ratos anestesiados com isoflurano. Utilizou-se 26 ratos Wistar, machos, com peso superior a 250 g, distribuídos de modo aleatório em três grupos de animais, designados: G1 (controle, isquemia; n = 8)
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Roos, Thomas. "The polyphenols resveratrol and caffeic acid phenethyl ester: their influence on growth-related signaling pathways in vascular smooth muscle cells." Diss., lmu, 2006. http://nbn-resolving.de/urn:nbn:de:bvb:19-60340.

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Roos, Thomas Ulrich. "The polyphenols resveratrol and caffeic acid phenethyl ester their influence on growth-related signaling pathways in vascular smooth muscle cells /." [S.l.] : [s.n.], 2006. http://edoc.ub.uni-muenchen.de/archive/00006034.

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Baranauskaitė, Agnė. "Kavos rūgšties fenetilo esterio poveikio inkstų mitochondrijoms tyrimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140618_215632-14448.

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Tyrimo tikslas: ištirti kavos rūgšties fenetilo esterio (CAFE) poveikį išemijos paveiktų žiurkės inkstų mitochondrijų funkcijoms. Uždaviniai: įvertinti tiesioginį in vitro CAFE poveikį inkstų mitochondrijų funkcijoms; CAFE poveikį išemijos (20 min) in vitro paveiktų inkstų mitochondrijų funkcijoms; kvėpavimo grandinės I komplekso aktyvumui; mitochondrijų gebėjimui kaupti Ca2+. Metodai. Wistar veislės žiurkių patinėliai buvo skirstomi į 4 grupes: kontrolinė grupė, 20 min trukmės išemijos, CAFE 22 mg/kg ir CAFE 34 mg/kg. CAFE buvo leidžiamas 1,5 h prieš sukeliant išemiją. Mitochondrijos buvo i
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Paracatu, Luana Chiquetto [UNESP]. "Estudo da relação entre estrutura química e atividade biológica de inibidores de NADPH Oxidase em leucócitos: relevância da oxidabilidade e hidrofobicidade." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/141533.

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Submitted by LUANA CHIQUETTO PARACATÚ null (luanachiquetto@hotmail.com) on 2016-07-14T18:15:23Z No. of bitstreams: 1 TESE - Luana Chiquetto.pdf: 2823701 bytes, checksum: 584996ba0cd6c6754d03400de9c6de73 (MD5)<br>Approved for entry into archive by Ana Paula Grisoto (grisotoana@reitoria.unesp.br) on 2016-07-18T20:01:01Z (GMT) No. of bitstreams: 1 paracatu_lc_dr_arafcf.pdf: 2823701 bytes, checksum: 584996ba0cd6c6754d03400de9c6de73 (MD5)<br>Made available in DSpace on 2016-07-18T20:01:01Z (GMT). No. of bitstreams: 1 paracatu_lc_dr_arafcf.pdf: 2823701 bytes, checksum: 584996ba0cd6c6754d03400de
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Anwar, Javed. "Os efeitos do ácido cafeico e do éster fenetil do ácido cafeico sobre as atividades da acetilcolinesterase e das ecto-nucleotidases em ratos." Universidade Federal de Santa Maria, 2013. http://repositorio.ufsm.br/handle/1/4459.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>Phenolic compouds and their derivatives constitute a leading family of natural compounds. Caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) are the important members of phenolic compound, sharing several biological applications; antioxidant, neuroprotective, anti-inflammatory, antiproliferative, antibacterial, antiviral, antiatherosclerotic and anticancer properties. In spite of these, literature reportes some of its pro-oxidants activity depending on cellular environment. These pathophysiolocal properties increased the i
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Mello, Rodrigo Brito de. "Produção de biblioteca de compostos derivados de produtos naturais: síntese e estudo de atividades biológicas." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/60/60138/tde-17042015-151409/.

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O presente trabalho trata da semissíntese de análogos de importantes compostos líderes (afidicolina, lausona, lapachol e CAPE) utilizando técnicas de química medicinal como bioisosterismo, adição de grupamento funcional e simplificação molecular. Dessa forma foi possível obter uma biblioteca de análogos racionais, visando a manipulação de parâmetros físico-químicos e estruturais, para fins de bioprospecção. Foram desenvolvidos derivados de afidicolina mais lipofílicos, por meio da acilação das hidroxilas presentes na estrutura química deste terpeno. Tentativas de formação de bioisósteros, sais
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Humphrey, Peter Saah. "Signal transduction mechanisms for stem cell differentation into cardiomyocytes." Thesis, University of Hertfordshire, 2009. http://hdl.handle.net/2299/3760.

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Cardiovascular diseases are among the leading causes of death worldwide and particularly in the developed World. The search for new therapeutic approaches for improving the functions of the damaged heart is therefore a critical endeavour. Myocardial infarction, which can lead to heart failure, is associated with irreversible loss of functional cardiomyocytes. The loss of cardiomyocytes poses a major difficulty for treating the damaged heart since terminally differentiated cardiomyocytes have very limited regeneration potential. Currently, the only effective treatment for severe heart failure i
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Souza, Flávia Castro Ribas de. "Efeitos dos inibidores de NF Kappa-B e Rho Quinase em um modelo de asma animal: comparação com o tratamento com corticosteroides." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5165/tde-28032018-093526/.

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Embora a grande maioria dos pacientes com asma tenha controle com o padrão de tratamento com corticosteroides, 5 a 10% destes asmáticos ainda desenvolvem algumas formas graves da doença e são considerados pacientes difíceis de controlar. A ativação do NFkB contribui para a manutenção e desenvolvimento de inflamação pulmonar crônica na fisiopatologia da asma. O éster fenetilico do ácido cafeico (CAPE), um componente ativo de própolis das colmeias de abelhas, é conhecido por ter propriedades antiinflamatórias e imunomoduladoras. É conhecido como um potente e um inibidor específico da ativação de
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Book chapters on the topic "Caffeic acid phenethyl ester (CAPE)"

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Rehman, Maqsood Ur, Abdullah, Fazlullah Khan, and Kamal Niaz. "Bee Propolis (Caffeic Acid Phenethyl Ester) Against Cancer." In Food Bioactive Ingredients. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-74035-1_5.

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Luo, Jian, Xiaolong Tang, and Anliang Dong. "Induction of Cancer Cell Senescence: Role of Caffeic Acid 3,4-Dihydroxy-Phenethyl Ester." In Tumor Dormancy, Quiescence, and Senescence, Vol. 3. Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9325-4_4.

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"Caffeic Acid (3,4-dihydroxycinnamic acid phenethyl ester, CAPE)." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_2185.

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"Total Synthesis of a Natural Product: Caffeic Acid Phenethyl Ester (CAPE)." In Advanced Organic Synthesis. CRC Press, 2015. http://dx.doi.org/10.1201/b19502-16.

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F., Mohamed, and Essam A. "Regulation of Apoptosis, Invasion and Angiogenesis of Tumor Cells by Caffeic Acid Phenethyl Ester." In Carcinogenesis. InTech, 2013. http://dx.doi.org/10.5772/55275.

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Roberto, Jos, Olga Beltrn-Ramrez, and Sal Villa-Trevio. "Searching for Analogues of the Natural Compound, Caffeic Acid Phenethyl Ester, with Chemprotective Activity." In A Compendium of Essays on Alternative Therapy. InTech, 2012. http://dx.doi.org/10.5772/29009.

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Kurata, Atsushi, Tokio Fujita, and Noriaki Kishimoto. "Biotransformation of Underutilized Natural Resource to Valuable Compounds in Ionic Liquid: Enzymatic Synthesis of Caffeic Acid Phenethyl Ester Analogues from Immature Coffee Beans." In Applications of Ionic Liquids in Science and Technology. InTech, 2011. http://dx.doi.org/10.5772/20966.

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Conference papers on the topic "Caffeic acid phenethyl ester (CAPE)"

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Pramanik, Kartick C., Shashi Kudugunti, Majid Moridani, and Sanjay K. Srivastava. "Abstract 2591: Caffeic acid phenethyl ester (CAPE) suppresses melanoma tumor growth by inhibiting AKT/XIAP pathway." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-2591.

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Omene, C., M. Patel, K. Karagoz, ML Gatza, and MH Barcellos-Hoff. "Abstract P4-07-03: Immunomodulation of triple negative breast cancer by caffeic acid phenethyl ester (CAPE)." In Abstracts: 2018 San Antonio Breast Cancer Symposium; December 4-8, 2018; San Antonio, Texas. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-p4-07-03.

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Omene, Coral O., Manan Patel, Irineu IllaBochaca, and Mary Helen Barcellos-Hoff. "Abstract 5247: Caffeic acid phenethyl ester (CAPE) reverses aggressive breast cancer in the radiation chimera model." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-5247.

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Omene, C., H. Martinez, H. Dave, et al. "Abstract P5-03-09: Phenotypic modulation of mammary stem cells by CAPE (caffeic acid phenethyl ester)." In Abstracts: Thirty-Sixth Annual CTRC-AACR San Antonio Breast Cancer Symposium - Dec 10-14, 2013; San Antonio, TX. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/0008-5472.sabcs13-p5-03-09.

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Omene, Coral O., Manan Patel, Kasthuri Kannan, Adriana Heguy, and Mary Helen Barcellos-Hoff. "Abstract 4232: CAPE (caffeic acid phenethyl ester) induces a mammary stem cell lineage restriction to a luminal phenotype via chromatin remodeling." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4232.

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Omene, C., M. Patel, I. Illa Bochaca, and MH Barcellos-Hoff. "Abstract P3-06-04: Modification and reversal of the aggressive behavior of triple negative breast cancer by caffeic acid phenethyl ester (CAPE)." In Abstracts: 2016 San Antonio Breast Cancer Symposium; December 6-10, 2016; San Antonio, Texas. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.sabcs16-p3-06-04.

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Omene, C., M. Patel, K. Kannan, A. Heguy, and MH Barcellos-Hoff. "Abstract P1-06-06: Mammary stem cell modulation of wildtype and Trp53 null stem cells by CAPE (caffeic acid phenethyl ester), a potential therapeutic agent." In Abstracts: Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium; December 8-12, 2015; San Antonio, TX. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.sabcs15-p1-06-06.

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Ceylan, Tayfun. "Protective effect of Caffeic acid phenethyl ester against cisplatin-induced nephrotoxicity in rats." In 15th International Congress of Histochemistry and Cytochemistry. LookUs Scientific, 2017. http://dx.doi.org/10.5505/2017ichc.pp-239.

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Ceylan, Tayfun. "Investigation Of Protective Effect Of Caffeic Acid Phenethyl Ester On Testicular Damage Which Was Caused By Cisplatin." In 15th International Congress of Histochemistry and Cytochemistry. LookUs Scientific, 2017. http://dx.doi.org/10.5505/2017ichc.pp-171.

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Kudugunti, Shashi, and Majid Moridani. "Abstract 746: Bioactivation of caffeic acid phenethyl ester prodrug by tyrosinase inhibits human glutathione S-transferase and cause selective toxicity to melanoma cells." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-746.

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Reports on the topic "Caffeic acid phenethyl ester (CAPE)"

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Bankova, Vassya, Boryana Trusheva, and Milena Popova. Caffeic Acid Phenethyl Ester (CAPE) – Natural Sources, Analytical Procedures and Synthetic Approaches. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2018. http://dx.doi.org/10.7546/crabs.2018.09.01.

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