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Dissertations / Theses on the topic 'Calcification, Physiologic'

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Published: 4 June 2021

Last updated: 3 February 2022

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1

Barragan-Adjemian, Maria del Cielo Bonewald Lynda F. "Mechanisms of mineralization in bone." Diss., UMK access, 2006.

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Thesis (Ph. D.)--School of Dentistry. University of Missouri--Kansas City, 2006.<br>"A dissertation in oral biology and cell biology and biophysics." Advisor: Lynda F. Bonewald. Typescript. Vita. Title from "catalog record" of the print edition Description based on contents viewed Nov. 12, 2007. Includes bibliographical references (leaves 121-139). Online version of the print edition.

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2

Bennett, Brian J. "Chondroplastic conversion and calcification of advanced atherosclerotic lesions : the impact of bone regulatory proteins and diet /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/6602.

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3

Curinga, Gabrielle Mercedes. "The role of runt-related transcription factor 2 in arterial smooth muscle cell mineralization /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/6353.

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4

Clark, Ruti H. "A model system for investigating biomineralization : elucidating protein G/calcium oxalate monohydrate interactions /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/8067.

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5

Bertucci, Daniela Vendrame. "Estudo sobre o efeito do atenolol na mineralização de dentes e ossos de filhotes de ratas espontaneamente hipertensas (SHR) e normotensas /." Araçatuba : [s.n.], 2009. http://hdl.handle.net/11449/95467.

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Orientador: Cristina Antoniali Silva<br>Banca: Alberto Carlos Botazzo Delbem<br>Banca: Carlos Ferreira dos Santos<br>Resumo: O tratamento da hipertensão durante a gravidez visa diminuir os riscos maternos e fetais. Entre os diferentes tipos de anti-hipertensivos que podem ser utilizados durante este período, estão os antagonistas dos receptores β-adrenérgicos. O atenolol é um antagonista seletivo de receptores 1-adrenérgicos que atravessa a barreira placentária e é excretado no leite materno chegando com facilidade ao feto de mães tratadas e aos recém-nascidos amamentados. Embora vários estudo

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6

Adragão, Maria Teresa Pulido. "Calcificações vasculares nos doentes em diálise : elo de ligação entre doença óssea e doença vascular." Doctoral thesis, Faculdade de Ciências Médicas. Universidade Nova de Lisboa, 2011. http://hdl.handle.net/10362/6298.

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RESUMO: A presente dissertação para tese de doutoramento apresenta o desenvolvimento e a validação de um método simples e original para o diagnóstico de calcificações vasculares em doentes em diálise, utilizando um score semiquantitativo criado por nós e obtido em RX simples da bacia e das mãos, denominado score de calcifi cação vascular simples. Demonstramos que este score vascular simples é preditor de risco cardiovascular nos doentes em diálise. O score de calcificação vascular simples associou-se ainda à baixa densidade mineral óssea avaliada por dual energy X -ray absortiometry (DXA) no

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7

Gilbert, Michele. "Design of synthetic peptides that display cell binding and signaling sequences on calcium phosphate surfaces /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/8063.

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8

Somogyi-Ganss, Eszter. "Novel non-collagenous modulators of biomineralization in bone and dentin /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-101-6/.

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9

Bertucci, Daniela Vendrame [UNESP]. "Estudo sobre o efeito do atenolol na mineralização de dentes e ossos de filhotes de ratas espontaneamente hipertensas (SHR) e normotensas." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/95467.

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Made available in DSpace on 2014-06-11T19:27:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-11-26Bitstream added on 2014-06-13T19:15:13Z : No. of bitstreams: 1 bertucci_dv_me_araca.pdf: 382588 bytes, checksum: 00700240bf69abe838e21d8e0b8b4fac (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>O tratamento da hipertensão durante a gravidez visa diminuir os riscos maternos e fetais. Entre os diferentes tipos de anti-hipertensivos que podem ser utilizados durante este período, estão os antagonistas dos receptores β-adrenérgicos. O atenolol é um antagonist

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10

Anderson, Paul Hamill. "The regulation of Vitamin D metabolism in the kidney and bone." Title page, contents and abstract only, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09pha5486.pdf.

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Includes bibliographical references (leaves 226-273.) Investigates the regulation of the expression of CYP27B1, CYP24 and vitamin D receptor (VDR) mRNA, both in the bone and in the kidney, with the aim to determine whether the regulation of the vitamin D metabolism in the bone is independent from that in the kidney. The effects of age, dietary calcium and vitamin D status on the expression of these genes in both the kidney and the bone, as well as on a number of biochemical factors known to regulate the renal metabolism of 1,25D, such as PTH, calcium and 1,25D itself, were examined. CYP27B1 mR

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11

Centurion, Bruna Stuchi. "Estudo de calcificações em tecidos moles em exames de tomografia computadorizada de feixe cônico e radiografia panorâmica digital." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/25/25149/tde-28092011-084001/.

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A maioria das calcificações em tecidos moles na região de cabeça e pescoço são achados radiográficos incidentais. Com o crescente uso da Tomografia Computadorizada de Feixe Cônico na Odontologia (TCFC) há um aumento do número desses achados, visto que o exame permite a visualização das estruturas em três dimensões. Esse estudo estabeleceu uma metodologia para identificar algumas dessas calcificações. Um observador calibrado analisou 100 exames de TCFC e as respectivas panorâmicas, quanto à presença de Ossificação do Complexo Estilo-Hióideo (OCEH), tonsilólitos e ateromas. Adicionalmente os p

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12

Liberman, Marcel. "Caracterização e mecanismos do desequilíbrio redox na fisiopatologia da estenose valvar aórtica degenerativa." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-23102007-185802/.

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Para investigar se estresse oxidativo contribui para a progressão da calcificação/estenose valvar aórtica (VA), avaliamos a produção de espécies reativas de oxigênio (ERO) e efeitos dos antioxidantes tempol e ác. lipóico em modelo de calcificação VA em coelhos. Superóxido, H2O2 e 3-nitrotirosina aumentaram em células inflamatórias e principalmente nos núcleos de calcificação, juntamente com as subunidades p22phox, Nox2 da NADPH oxidase e da proteína dissulfeto isomerase, que co-localizam. PCR mostrou aumento da Nox4 em relação a Nox1. A calcificação foi menor com ác.lipóico e maior com tempol,

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13

Kangwe, Juma W. "Calcareous Algae of a Tropical Lagoon : Primary Productivity, Calcification and Carbonate Production." Doctoral thesis, Stockholm : Department of Botany, Stockholm University, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-784.

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14

Bernardet, Coralie. "Physiologie des transports ioniques et moléculaires chez les coraux, implications environnementales." Electronic Thesis or Diss., Sorbonne université, 2019. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2019SORUS496.pdf.

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Les coraux tropicaux constructeurs de récifs sont à l’origine d’écosystèmes extrêmement riches dont dépendent de nombreuses espèces, y compris l’Homme. Aujourd’hui, les changements climatiques représentent toutefois une menace pour la survie des coraux. Afin de comprendre la réponse de ces espèces aux modifications environnementales, il est essentiel d’avoir des informations sur la physiologie de ces espèces-clé. Les travaux conduits au cours de ma thèse ont ainsi permis de caractériser, au niveau mécanistique, les processus affectés par des changements de température chez l’espèce Stylophora

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15

Yu, Elizabeth A. "Investigating Age-Dependent Arthropathy in a Circadian Mutant Mouse Model: A Dissertation." eScholarship@UMMS, 2011. https://escholarship.umassmed.edu/gsbs_diss/544.

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Ectopic calcification can cause pain and limit mobility. Studies suggest that circadian genes may play a role in the calcification process. Core circadian genes Clock, Npas2, and Bmal1 are transcription factors that form CLOCK:BMAL1 or NPAS2:BMAL1 transactivator complexes that drive the rhythmic expression of circadian oscillator genes and output genes. Circadian oscillator genes Period1-3 and Cryptochrome1-2 encode proteins that form transcription repressor complexes that feedback to inhibit CLOCK/NPAS2:BMAL1 activity, thus completing the feedback loop that is the basis of the molecular circa

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16

Bagusche, Frauke. "Environmental effects on the physiology of calcification in the Pacific oyster Crassostrea gigas Thunberg, 1793." Thesis, University of Southampton, 2013. https://eprints.soton.ac.uk/355539/.

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17

Abdallah, Dina. "Fonctions de la phospholipase D et des récepteurs de la prostaglandine PGE2 durant la maturation des ostéoblastes, le processus de la minéralisation physiologique et la calcification cardiovasculaire." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10152/document.

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Le métabolisme lipidique affecte la maturation et la différenciation des cellules osseuses. L'objectif de ma thèse est d'approfondir deux aspects du métabolisme lipidique mal connus, soit les actions de la phospholipase D (PLD) et celles des récepteurs de prostaglandine PGE2 pendant la différenciation des cellules. Une lignée humaine, les Saos-2 et les ostéoblastes primaires issus de calvaria de souriceaux ont servi de modèles cellulaires de la minéralisation physiologique. La culture d'aorte ex vivo sous des conditions d'hyperphosphatémie a été utilisée pour reproduire la calcification de l'a

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18

Lim, Kenneth Jia-En. "Role of Klotho in the development of vascular calcification in patients with chronic kidney disease (CKD)." Thesis, University of Warwick, 2012. http://wrap.warwick.ac.uk/50202/.

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Background: Cardiovascular disease is the leading cause of mortality in patients with Chronic Kidney Disease (CKD). Vascular calcification is a significant contributor to cardiovascular mortality in CKD. Klotho is a 130kDa transmembrane protein with cardiovasculo-protective properties and also functions as a co-factor for the phosphatonin, fibroblast growth factor (FGF)-23 at the kidney. FGF-23 levels rise in CKD despite progression of accelerated vascular calcification (VC). There are currently conflicting data on whether FGF-23 may exhibit direct vasculo-protective effects in CKD. Methods an

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19

Côté, Nancy. "Étude des mécanismes d'inflammation, de fibrose et de calcification impliqués dans le développement de la sténose aortique. Importance des systèmes rénine-angiotensine et ecto-purinergique dans la sténose aortique." Thesis, Université Laval, 2013. http://www.theses.ulaval.ca/2013/29635/29635.pdf.

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20

Prosdocimo, Domenick A. "Extracellular Pyrophosphate Homeostasis and Regulation of Vascular Calcification in Vascular Smooth Muscle Cells." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1266605413.

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21

Ebanks, Sue C. "The Common Pond Snail Lymnaea stagnalis: Extracellular Fluid Recovery in Adults and Calcification and Lead Sensitivity During Embryonic Development." Scholarly Repository, 2010. http://scholarlyrepository.miami.edu/oa_dissertations/658.

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Freshwater organisms are known to maintain hyperosmotic internal conditions despite outward diffusive loss of ions. The freshwater common pond snail Lymnaea stagnalis faces this challenge while additionally attaining the necessary ions for calcification. These are the first documented assessments of the time and mode of recovery for ions lost due to full-body withdrawal in adults of this species. Additionally, this document reports on the physiological and developmental onset of embryonic calcification and the commencement of active acquisition of shell-forming ions from the surrounding env

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22

Esterle, Laure. "Facteurs nutritionnels et génétiques associés à la santé osseuse chez l'enfant et l'adolescent en bonne santé." Paris 5, 2009. http://www.theses.fr/2009PA05T044.

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L'enfance et l'adolescence sont des périodes cruciales pour la minéralisation du squelette. J'ai montré que la minéralisation des vertèbres lombaires pendant l' adolescence était associée à la consommation de lait plus qu'à celle d'autres sources de calcium. Le polymorphisme associé à l'hypolactasie n'est pas corrélé à l'acquisition de la masse osseuse pendant l'adolescence. En revanche, le polymorphisme en -1012 du VDRp influence l'association entre la minéralisation osseuse des vertèbres lombaires et les apports en lait. Les jeunes filles porteuses des variants G/A et G/G en - 1012 VDRp (70

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23

Rollion-Bard, Claire. "Variabilité des isotopes de l'oxygène dans les coraux Porites : développement et implications des microanalyses d'isotopes stables (B, C ET O) par sonde ionique." Nancy 1, 2001. http://docnum.univ-lorraine.fr/public/INPL_T_2001_ROLLION-BARD_C.pdf.

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Des mesures des compositions isotopiques de bore, de carbone et d'oxygène par sonde ionique ont été développées sur des carbonates avec des reproductibilités internes de l'ordre 0,2 ‰ et des reproductibilités externes de l'ordre de 0,9 ‰ pour le bore, 0,65 ‰ pour le carbone et 0,4 ‰ pour l'oxygène. Les volumes analysés sont compris entre 3,5. 10-7 et 58,9. 1 0-7 mm³. Les coraux fournissent un enregistrement des conditions chimiques et physiques de l'eau de mer environnante au moment de la précipitation de leur squelette carbonaté. Leurs δ¹³C et δ¹⁸0 apparaissent en déséquilibre par rapport aux

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24

Dos, Ramos Catarino Ana Isabel. "Temperate and cold water sea urchin species in an acidifying world: coping with change?" Doctoral thesis, Universite Libre de Bruxelles, 2011. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209914.

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Anthropogenic carbon dioxide (CO2) emissions are increasing the atmospheric CO2 concentration and the oceans are absorbing around 1/3 them. The CO2 hydrolysis increases the H+ concentration, decreasing the pH, while the proportions of the HCO3- and CO32- ions are also affected. This process already led to a decrease of 0.1 pH units in surface seawater. According to "business-as-usual" models, provided by the Intergovernmental Panel on Climate Change (IPCC), the pH is expected to decrease 0.3-0.5 units by 2100 and 0.7-0.8 by 2300. As a result the surface ocean carbonates chemistry will also cha

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Trout, G. E. "Studies on nutritionally induced soft-tissue calcification in the rat." Thesis, 2014.

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26

"Biosynthesis, characterization and implantation of artificial growth plate using 3-D chondrocyte pellet culture." 1998. http://library.cuhk.edu.hk/record=b5896314.

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by Cheng Sze Lok, Alfred.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1998.<br>Includes bibliographical references (leaves 104-109).<br>Abstract also in Chinese.<br>DECLARATION --- p.i<br>ABSTRACT --- p.ii<br>ACKNOWLEDGEMENT --- p.vii<br>ABBREVIATIONS --- p.ix<br>LIST OF FIGURES --- p.x<br>LIST OF TABLES --- p.xii<br>TABLE OF CONTENTS --- p.xiii<br>Chapter CHAPTER ONE 226}0ؤ --- INTRODUCTION<br>Chapter 1.1 --- The Growth Plate<br>Chapter 1.1.1 --- "Function, Structure and Biochemistry of the Growth Plate" --- p.1<br>Chapter 1.1.2 --- Extracellular Matrix of the Growth Plate C

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27

"Abnormal bone mineralization in adolescent idiopathic scoliosis and its relation with plasma and tissue expression of osteopontin." 2012. http://library.cuhk.edu.hk/record=b5549402.

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青少年特發性脊柱側凸(Adolescent idiopathic scoliosis , AIS)是一種複雜的脊柱三維畸形，常見於10-16 歲處於生長發育高峰期的青少年女性。儘管AIS 發生率較高並且臨床影響較大，但是到目前為止其病因未明。在眾多關於AIS 病因學的假設和理論研究中，普遍認為低骨密度是AIS 的一個重要影響因素。然而近年來對於AIS 患者低骨密度研究不足，其潛在的機制尚不明確。我們之前初步的組織學研究發現，AIS 患者的松質骨中成骨細胞功能下降，此研究為AIS中存在骨礦化異常提供了初步依據。<br>骨橋蛋白是骨組織中一種重要的非膠原細胞外基質蛋白，其在骨礦化過程中起著重要作用。近期的研究報導AIS 患者血漿中骨橋蛋白水準高於年齡匹配的正常對照。因此本研究假設AIS 患者血漿及骨組織中骨橋蛋白高於正常對照，并可能影響了骨基質的礦化，從而導致低骨密度。<br>本系列研究的第一部分旨在通過外周定量電腦斷層掃描（pQCT）明確AIS患者中皮質骨密度及松質骨密度是否均低於正常對照。pQCT 可以準確地三維評估皮質骨密度，松質骨密度及其他骨品質的相關參數。採用雙能X 線骨密度儀（DXA）測量受試者的非優勢側近端股骨面積骨密度（包括股骨頸，Ward’s 三角及大轉子）。而採用pQCT 測量受試者非優勢側橈骨遠端容積骨密度，包括皮質骨密度及松質骨密度。結果顯示AIS 患者面積骨密

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28

"Abnormal skeletal growth and bone mineralization in the etiopathogenesis of adolescent idiopathic scoliosis." 2002. http://library.cuhk.edu.hk/record=b6073509.

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by Tang Shengping.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2002.<br>Includes bibliographical references (p. 217-244).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.

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29

McKenney, Mikaela Lee. "Coronary artery disease progression and calcification in metabolic syndrome." Thesis, 2014. http://hdl.handle.net/1805/6460.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>For years, the leading killer of Americans has been coronary artery disease (CAD), which has a strong correlation to the U.S. obesity epidemic. Obesity, along with the presence of other risk factors including hyperglycemia, hypercholesterolemia, dyslipidemia, and high blood pressure, comprise of the diagnosis of metabolic syndrome (MetS). The presentation of multiple MetS risk factors increases a patients risk for adverse cardiovascular events. CAD is a complex progressive disease. We utilized the superb model of CAD and MetS, the Os

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30

Weinzierl, Michael. "Physiological performance and thermal tolerance of major Red Sea macrophytes." Thesis, 2017. http://hdl.handle.net/10754/626310.

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As anthropogenically-forced ocean temperatures continue to rise, the physiological response of marine macrophytes becomes exceedingly relevant. The Red Sea is a semi-isolated sea- the warmest in the world (SST up to 34°C) - already exhibiting signs of rapid warming rates exceeding those of other tropical oceans. This will have profound effects on the physiology of marine organisms, specifically marine macrophytes, which have direct influence on the dynamic carbonate system of the Red Sea. The aim of this paper is to define the physiological capability and thermal optima and limits of six ecolo

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Koranteng, Promise Nonceba. "The prevalence of incidental physiological intracranial calcifications in the South African adult population as seen on computed tomography." Thesis, 2016. http://hdl.handle.net/10539/23172.

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A research report submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, in partial fulfillment of the requirements for the degree of Master of Medicine in Diagnostic Radiology Johannesburg, 2016<br>MT2017

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