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Relevant bibliographies by topics / Calcifying Tumor Markers

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Journal articles

Academic literature on the topic 'Calcifying Tumor Markers'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Calcifying Tumor Markers"

1

Shah, Yashvi, Rashmi Metgud, Smitha Naik, and Aniruddh Tak. "Immunohistochemistry in Oral Pathologies: Diagnostic and Prognostic Perspectives." IOSR Journal of Dental and Medical Sciences 24, no. 6 (2025): 40–46. https://doi.org/10.9790/0853-2406054046.

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Immunohistochemistry (IHC) has revolutionized the diagnostic and prognostic landscape of oral pathology by enabling precise detection of specific antigens within tissue sections. This article offers a comprehensive overview of IHC’s evolution, fundamental principles, and practical techniques—ranging from direct and indirect labeling to advanced polymer- and gold-based methods. Emphasis is placed on the meticulous preparation of tissues, including formalin fixation and antigen retrieval, to ensure reliable staining outcomes. A detailed exploration of molecular markers follows, illustrating how

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2

Crocker, Melissa K., Evgenia Gourgari, Maya Lodish, and Constantine A. Stratakis. "Use of Aromatase Inhibitors in Large Cell Calcifying Sertoli Cell Tumors: Effects on Gynecomastia, Growth Velocity, and Bone Age." Journal of Clinical Endocrinology & Metabolism 99, no. 12 (2014): E2673—E2680. http://dx.doi.org/10.1210/jc.2014-2530.

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Context: Large cell calcifying Sertoli cell tumors (LCCSCT) present in isolation or, especially in children, in association with Carney Complex (CNC) or Peutz-Jeghers Syndrome (PJS). These tumors overexpress aromatase (CYP19A1), which leads to increased conversion of delta-4-androstenedione to estrone and testosterone to estradiol. Prepubertal boys may present with growth acceleration, advanced bone age, and gynecomastia. Objective: To investigate the outcomes of aromatase inhibitor therapy (AIT) in prepubertal boys with LCCSCTs. Design: Case series of a very rare tumor and chart review of cas

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3

Zhou, Jun, Luting Zhou, Sheng Wu, et al. "Clinicopathologic Study of Calcifying Fibrous Tumor Emphasizing Different Anatomical Distribution and Favorable Prognosis." BioMed Research International 2019 (July 2, 2019): 1–8. http://dx.doi.org/10.1155/2019/5026860.

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Aims. Calcifying fibrous tumor (CFT) is a very rare begin fibroblastic tumor featuring a widely anatomical distribution and may mimic various spindle cell tumors. Misdiagnosis and hence mistreatment are likely caused due to unfamiliarity to clinicians or junior pathologists. We collected a relatively large series of CFTs in our institution aiming at further summarizing their clinicopathologic features in Chinese patients and discussing the diagnosis and differential diagnosis in clinical practice. Methods. Clinicopathologic data of 22 CFTs were retrospectively reviewed. Histologic features wer

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4

Kulkarni, Spoorti, Harishanker Alampally, Vasudev Guddattu, Gabriel Rodrigues, and Sunitha Carnelio. "Expression of Fascin and SALL4 in odontogenic cysts and tumors: an immunohistochemical appraisal." F1000Research 11 (June 27, 2024): 1578. http://dx.doi.org/10.12688/f1000research.126091.5.

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Background Various stemness markers (SOX2, OCT4, and NANOG) have been studied in odontogenic cysts and tumors. However, studies on SALL4 having similar properties of stemness has not been documented. Additionally, insight into fascin as a migratory molecule is less explored. In this study, the expression of SALL4 and fascin were evaluated in ameloblastoma, adenomatoid odontogenic tumor (AOT), odontogenic keratocyst (OKC), dentigerous cyst (DC), radicular cyst (RC), and calcifying odontogenic cyst (COC). Methods Semi-quantitative analysis of fascin and SALL4 immuno-positive cells was done in a

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5

Kulkarni, Spoorti, Harishanker Alampally, Vasudev Guddattu, Gabriel Rodrigues, and Sunitha Carnelio. "Expression of Fascin and SALL4 in odontogenic cysts and tumors: an immunohistochemical appraisal." F1000Research 11 (December 23, 2022): 1578. http://dx.doi.org/10.12688/f1000research.126091.1.

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Background: Various stemness markers (SOX2, OCT4, and NANOG) have been studied in odontogenic cysts and tumors. However, studies on SALL4 having similar properties of stemness has not been documented. Additionally, insight into fascin as a migratory molecule is less explored. In this study, the expression of SALL4 and fascin were evaluated in ameloblastoma, adenomatoid odontogenic tumor (AOT), odontogenic keratocyst (OKC), dentigerous cyst (DC), radicular cyst (RC), and calcifying odontogenic cyst (COC). Methods: Semi-quantitative analysis of fascin and SALL4 immuno-positive cells was done in

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6

Kulkarni, Spoorti, Harishanker Alampally, Vasudev Guddattu, Gabriel Rodrigues, and Sunitha Carnelio. "Expression of Fascin and SALL4 in odontogenic cysts and tumors: an immunohistochemical appraisal." F1000Research 11 (December 14, 2023): 1578. http://dx.doi.org/10.12688/f1000research.126091.3.

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Abstract:

Background Various stemness markers (SOX2, OCT4, and NANOG) have been studied in odontogenic cysts and tumors. However, studies on SALL4 having similar properties of stemness has not been documented. Additionally, insight into fascin as a migratory molecule is less explored. In this study, the expression of SALL4 and fascin were evaluated in ameloblastoma, adenomatoid odontogenic tumor (AOT), odontogenic keratocyst (OKC), dentigerous cyst (DC), radicular cyst (RC), and calcifying odontogenic cyst (COC). Methods Semi-quantitative analysis of fascin and SALL4 immuno-positive cells was done in a

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7

Kulkarni, Spoorti, Harishanker Alampally, Vasudev Guddattu, Gabriel Rodrigues, and Sunitha Carnelio. "Expression of Fascin and SALL4 in odontogenic cysts and tumors: an immunohistochemical appraisal." F1000Research 11 (June 10, 2024): 1578. http://dx.doi.org/10.12688/f1000research.126091.4.

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Abstract:

Background Various stemness markers (SOX2, OCT4, and NANOG) have been studied in odontogenic cysts and tumors. However, studies on SALL4 having similar properties of stemness has not been documented. Additionally, insight into fascin as a migratory molecule is less explored. In this study, the expression of SALL4 and fascin were evaluated in ameloblastoma, adenomatoid odontogenic tumor (AOT), odontogenic keratocyst (OKC), dentigerous cyst (DC), radicular cyst (RC), and calcifying odontogenic cyst (COC). Methods Semi-quantitative analysis of fascin and SALL4 immuno-positive cells was done in a

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8

Kulkarni, Spoorti, Harishanker Alampally, Vasudev Guddattu, Gabriel Rodrigues, and Sunitha Carnelio. "Expression of Fascin and SALL4 in odontogenic cysts and tumors: an immunohistochemical appraisal." F1000Research 11 (September 1, 2023): 1578. http://dx.doi.org/10.12688/f1000research.126091.2.

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Abstract:

Background: Various stemness markers (SOX2, OCT4, and NANOG) have been studied in odontogenic cysts and tumors. However, studies on SALL4 having similar properties of stemness has not been documented. Additionally, insight into fascin as a migratory molecule is less explored. Following a thorough literature search we hypothesize that fascin might contribute for the local migratory behaviour of the odontogenic epithelial cells in tumors and cysts while SALL4 may contribute to stemness property. Thus, the aim of the present study was to evaluate the expression of fascin and SALL4 in histopatholo

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9

Lefevre, Hervé, Claire Bouvattier, Najiba Lahlou, Catherine Adamsbaum, Pierre Bougnères, and Jean-Claude Carel. "Prepubertal gynecomastia in Peutz-Jeghers syndrome: incomplete penetrance in a familial case and management with an aromatase inhibitor." European Journal of Endocrinology 154, no. 2 (2006): 221–27. http://dx.doi.org/10.1530/eje.1.02085.

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Background: Peutz-Jeghers syndrome (PJS) is a rare autosomal-dominant disorder characterized by multiple gastrointestinal hamartomatous polyps, mucocutaneous pigmentation and increased predisposition to various neoplasms. Endocrine manifestations in PJS include gynecomastia due to calcified Sertoli cell testicular tumors usually referred to as large-cell calcifying Sertoli cell tumors (LSCT). Objective: To evaluate the value of endocrine markers and aromatase inhibitor treatment in children with PJS and LSCT. Design and setting: Familial cases, followed in a tertiary care center. Patients: Two

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10

Simões-Pereira, Joana, Filipa Santos, Lurdes Lopes, and Catarina Limbert. "Prepubertal gynaecomastia in a boy with Peutz-Jeghers syndrome: managing the aromatase overexpression." Journal of Pediatric Endocrinology and Metabolism 31, no. 10 (2018): 1149–54. http://dx.doi.org/10.1515/jpem-2017-0455.

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Abstract Background Gynaecomastia, although rarely related to testicular tumours, in boys with Peutz-Jeghers syndrome (PJS) usually occurs due to large-cell calcifying Sertoli cell tumour (LCCSCT). Case presentation A 4-year-old boy, with a genetic diagnosis of PJS, presented gynaecomastia since the age of 2, associated with increased height velocity (HV). He exhibited bilateral breast enlargement (Tanner-B4) and a testicular volume of 4 mL. Testicular ultrasound revealed multifocal microcalcifications in both testicles. A laboratory evaluation showed undetectable gonadotrophins, testosterone

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