Academic literature on the topic 'Calcium buffers'

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Journal articles on the topic "Calcium buffers"

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Snow, P., and R. Nuccitelli. "Calcium buffer injections delay cleavage in Xenopus laevis blastomeres." Journal of Cell Biology 122, no. 2 (1993): 387–94. http://dx.doi.org/10.1083/jcb.122.2.387.

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Microinjection of calcium buffers into the two-cell Xenopus laevis embryo delays cell division in a dose-dependent manner. Four calcium buffers in the BAPTA series with different affinities for calcium were used to distinguish between a localized calcium gradient regulating cleavage and the global calcium concentration regulating this event. DibromoBAPTA (Kd = 1.5 microM) was found to delay cleavage at the lowest intracellular concentration (1.3 mM) of the four buffers tested. The effectiveness of the calcium buffers was dependent upon the buffer dissociation constant but not in a linear fashi
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Prins, D., and M. Michalak. "Organellar Calcium Buffers." Cold Spring Harbor Perspectives in Biology 3, no. 3 (2011): a004069. http://dx.doi.org/10.1101/cshperspect.a004069.

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McMahon, Shane M., Che-Wei Chang, and Meyer B. Jackson. "Multiple cytosolic calcium buffers in posterior pituitary nerve terminals." Journal of General Physiology 147, no. 3 (2016): 243–54. http://dx.doi.org/10.1085/jgp.201511525.

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Cytosolic Ca2+ buffers bind to a large fraction of Ca2+ as it enters a cell, shaping Ca2+ signals both spatially and temporally. In this way, cytosolic Ca2+ buffers regulate excitation-secretion coupling and short-term plasticity of release. The posterior pituitary is composed of peptidergic nerve terminals, which release oxytocin and vasopressin in response to Ca2+ entry. Secretion of these hormones exhibits a complex dependence on the frequency and pattern of electrical activity, and the role of cytosolic Ca2+ buffers in controlling pituitary Ca2+ signaling is poorly understood. Here, cytoso
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Speksnijder, J. E., A. L. Miller, M. H. Weisenseel, T. H. Chen, and L. F. Jaffe. "Calcium buffer injections block fucoid egg development by facilitating calcium diffusion." Proceedings of the National Academy of Sciences 86, no. 17 (1989): 6607–11. http://dx.doi.org/10.1073/pnas.86.17.6607.

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The polarity of fucoid eggs is fixed either when tip growth starts or a bit earlier. A steady flow of calcium ions into the incipient tip is thought to establish a high calcium zone that is needed for its localization and formation. To test this hypothesis, we have injected seven different 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA)-type calcium buffers into Pelvetia eggs many hours before tip growth normally starts. Critical final cell concentrations of each buffer prove to block outgrowth (as well as cell division) for up to 2 weeks. This critical inhibitory concentratio
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Carrera, Germán, Amparo Gil, Javier Segura, and Bernat Soria. "Software for simulating calcium-triggered exocytotic processes." American Journal of Physiology-Cell Physiology 292, no. 2 (2007): C749—C755. http://dx.doi.org/10.1152/ajpcell.00082.2006.

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We describe a software package for the simulation of exocytotic events from readily releasable pools of secretory vesicles in neuroendocrine cells and presynaptic terminals. The visual package Ca3D_Exolab simulates the entry of Ca2+ through the calcium channels, the kinetic reactions of calcium with buffers, the diffusion of calcium and mobile buffers, and the kinetic reactions of calcium with the secretory vesicles. The location of both channels and secretory vesicles can be set by using a graphical interface. Calcium and buffer concentrations at different depths from the cellular membrane an
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Lindsay, H. D., M. J. Whitaker, and C. C. Ford. "Calcium requirements during mitotic cdc2 kinase activation and cyclin degradation in Xenopus egg extracts." Journal of Cell Science 108, no. 11 (1995): 3557–68. http://dx.doi.org/10.1242/jcs.108.11.3557.

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Activation of p34cdc2 kinase is essential for entry into mitosis while subsequent deactivation and cyclin degradation are associated with exit. In Xenopus embryos, both of these phases are regulated by post-translation modifications and occur spontaneously on incubation of extracts prepared late in the first cell cycle. Even though high levels of calcium buffer were initially used to prepare these extracts, we found that free calcium levels in them remained in the observed physiological range (200-500 nM). Further addition of calcium buffers only slightly reduced free calcium levels, but inhib
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Neher, Erwin. "Calcium Buffers in Flash-Light." Biophysical Journal 79, no. 6 (2000): 2783–84. http://dx.doi.org/10.1016/s0006-3495(00)76517-9.

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McMahon, Shane M., and Meyer B. Jackson. "An Inconvenient Truth: Calcium Sensors Are Calcium Buffers." Trends in Neurosciences 41, no. 12 (2018): 880–84. http://dx.doi.org/10.1016/j.tins.2018.09.005.

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Crowell, J. A., and G. N. Bowers. "Apparent binding of ionized calcium by various buffers." Clinical Chemistry 31, no. 2 (1985): 267–70. http://dx.doi.org/10.1093/clinchem/31.2.267.

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Abstract Using different substance concentrations in an aqueous 1.25 mmol/L solution of CaCl2 plus NaCl to a final solution ionic strength of 160 mmol/L, we tested six buffers for their effect on measurements of ionized calcium (Ca2+). Measured Ca2+ decreased with increasing ionic strength and pH. Increasing concentrations of Tris caused a positive Ca2+ electrode bias; the other five buffers caused a negative Ca2+ electrode bias with increasing concentration. 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid ("HEPES") at 10 mmol/L maintained pH 7.39 in the aqueous reference solutions containi
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Holt, Carl, D. Thomas Davies, and Andrew J. R. Law. "Effects of colloidal calcium phosphate content and free calcium ion concentration in the milk serum on the dissociation of bovine casein micelles." Journal of Dairy Research 53, no. 4 (1986): 557–72. http://dx.doi.org/10.1017/s0022029900033082.

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SummaryThe strength of binding of the individual caseins and the nature of the bonding within bovine casein micelles were examined through dissociation of the micelles by dialysis of skim milk either against phosphate-free buffers containing 3 or 6 mm-CaCl2, or against buffers that were nearly saturated with respect to micellar calcium phosphate, but which had a free Ca2+ concentration in the range 0·4–5·9 mm. Dissociation was followed by ultracentrifuging the dialysed milks and determining the partition of the total and the individual caseins between the pellet and serum. During dialysis agai
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Dissertations / Theses on the topic "Calcium buffers"

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Andrianjafiniony, Tina. "Atrophie musculaire et récupération : homéostasie calcique, stress oxydant, apoptose et protéolyse musculaire." Thesis, Lyon 1, 2010. http://www.theses.fr/2010LYO10171.

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L’exposition à une situation d’hypokinésie induit une atrophie fonctionnelle et phénotypique du musclesquelettique. Différents mécanismes sont suggérés contribuer à ce phénomène de plasticité musculaire,incluant en particulier des modifications de l’homéostasie calcique et de la production d’espèces réactivesde l’oxygène qui, en relation avec certains processus inflammatoires, activeraient des voies d’apoptose etde protéolyse musculaire. Le présent travail a porté un intérêt spécifique à ces phénomènes dans le cadrede l’atrophie musculaire induite par une hypokinésie ainsi que dans la récupéra
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Arruda, Dorival Pires de 1962. "Avaliação de extratores químicos na determinação de silício disponível em solos cultivados com cana-de-açúcar /." Botucatu : [s.n.], 2009. http://hdl.handle.net/11449/90652.

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Resumo: Existem vários extratores que avaliam a disponibilidade de silício no solo. Nos Estados Unidos utiliza-se como extrator químico o ácido acético 0,5 mol L-1 , o qual já foi usado no Brasil, mas recentemente foi substituído pelo cloreto de cálcio 0,01 mol L-1, o mesmo utilizado na Austrália. Os extratores, de forma geral, são dependentes das características físicas do solo, principalmente do teor de argila, e podem subestimar ou superestimar os teores de silício no solo. Na literatura não há relatos de extratores de silício que se assemelhem às raízes das plantas, como é o caso da resina
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Arruda, Dorival Pires de [UNESP]. "Avaliação de extratores químicos na determinação de silício disponível em solos cultivados com cana-de-açúcar." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/90652.

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Made available in DSpace on 2014-06-11T19:24:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-08-31Bitstream added on 2014-06-13T18:52:34Z : No. of bitstreams: 1 arruda_dp_me_botfca.pdf: 628799 bytes, checksum: c0a1f52e914545883936131898e973ff (MD5)<br>Existem vários extratores que avaliam a disponibilidade de silício no solo. Nos Estados Unidos utiliza-se como extrator químico o ácido acético 0,5 mol L-1 , o qual já foi usado no Brasil, mas recentemente foi substituído pelo cloreto de cálcio 0,01 mol L-1, o mesmo utilizado na Austrália. Os extratores, de forma geral, são dependente
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Junior, Walter Luiz Siqueira. ""Estudo de alguns parâmetros salivares em indivíduos com síndrome de DOWN"." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/23/23140/tde-13062005-115943/.

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O objetivo deste estudo foi mensurar o fluxo salivar, pH, capacidade tampão, concentrações de proteína total e ácido siálico, atividades das enzimas amilase e peroxidase e concentração dos íons sódio, potássio, cálcio, fósforo, zinco e magnésio em saliva total de indivíduos síndrome de Down com idade entre 1 e 25 anos. Nos indivíduos com idade entre 1 e 5 anos a saliva total foi coletada através de uma leve sucção, enquanto que nos outros indivíduos com idade entre 6 e 10, 11 e 15, 15 e 20, 21 e 25 a saliva total foi coletada com estimulação mecânica através da mastigação de parafilm, durante
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Abdel-Hamid, Khaled Mohammed. "The regulation of intracellular calcium in cultured hippocampal neurons and the influence of calcium buffers." Thesis, 1994. http://hdl.handle.net/2429/8736.

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Excessive activation of the major neurotransmitter glutamate receptors has been blamed as a causative mechanism in a large number of neuro-pathological situations via a process known as excitotoxicity. Excessive influx of calcium (Ca²+, and the consequent loss of Ca²+ homeostasis in neurons subject to this form of excessive activation have been suggested to play a central role in the triggering of a series of events ending in neuronal death. Neuronal populations differ in their vulnerability to excitotoxicity and this difference has, controversially, been attributed to the variability in
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Weil, Sara. "Calcium and Potassium Accumulation in Lettuce under Different Nitrogen Regimes." 2015. https://scholarworks.umass.edu/masters_theses_2/304.

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Nutrient accumulation in vegetable crops is declining. New varieties, selected for high yield, may be subject to a dilution effect of nutrient concentration. Alternatively, soil fertility may be to blame. Here, we investigate how nitrogen fertilization can enhance or suppress calcium and potassium content in two lettuce varieties already known to accumulate high or low amounts of these nutrients. Effects of varying the ammonium:nitrate ratio and effects of calcium carbonate buffering on plant growth by mass and on uptake and accumulation of potassium and calcium in two lettuce (Lactuca sativa
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Picher, Maria Magdalena. "The role of Calcium Binding Protein 2 in synaptic sound encoding and hearing." Doctoral thesis, 2015. http://hdl.handle.net/11858/00-1735-0000-002B-7CC1-F.

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Cishek, Dawn M. "Calcium buffer incorporation reversibly inhibits DNA synthesis, nuclear envelope breakdown, and cell division in transformed keratinocytes." 1996. https://scholarworks.umass.edu/dissertations/AAI9638947.

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Loss of regulation of cell cycle events mediated by changes in cytosolic Ca$\sp{2+}$ ion activity has been implicated in the progression of normal cells to neoplasia. In this study, the Ca$\sp{2+}$ buffer 5,5$\sp\prime$-difluoro 1,2-bis(2-aminophenoxy) ethane-N,N,N$\sp\prime N\sp\prime$-tetra-acetic acid (5,5$\sp\prime$-dfBAPTA, abbreviated "dfB") has been used to modulate cell division in transformed and primary mouse keratinocytes. Exogenous application, via the tetra(acetoxymethyl) ester ("AM"), of 18-20 $\mu$M dfB/AM to the growth media of transformed cells inhibits cell division and DNA s
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Jaiswal, Manoj Kumar. "Optical Analysis of [Ca2+]i and Mitochondrial Signaling Pathways: Implications for the Selective Vulnerability of Motoneurons in Amyotrophic Lateral Sclerosis (ALS)." Doctoral thesis, 2008. http://hdl.handle.net/11858/00-1735-0000-0006-B65A-C.

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Books on the topic "Calcium buffers"

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Ouanounou, Aviv. Modulation of synaptic transmission by exogenous calcium buffers in hippocampal CA1 neurons. National Library of Canada, 1996.

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Clarke, Andrew. Water. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780199551668.003.0005.

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Liquid water is essential for life, and a metabolically active cell is ~70% water. The physical properties of liquid water, and their temperature dependence, are dictated to a significant extent by the properties of hydrogen bonds. From an ecological perspective, the important properties of liquid water include its high latent heats of fusion and vapourisation, its high specific heat, the ionisation, low dynamic viscosity and high surface tension. The solubility in water of oxygen, carbon dioxide and the calcium carbonate used to build skeletons in many invertebrates groups all increase with d
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Book chapters on the topic "Calcium buffers"

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Bergmann, F., and B. U. Keller. "Glutamate, Calcium and Neurodegenerative Disease: Impact of Cytosolic Calcium Buffers and Their Potential Role for Neuroprotective Strategies." In Brain Damage and Repair. Springer Netherlands, 2004. http://dx.doi.org/10.1007/1-4020-2541-6_23.

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Silva, E. T. N. T., R. R. Silva, and D. G. Goroso. "Computer Simulations on the Influence of NCLX and Buffers Calcium in Rat Cardiac Myocyte." In VI Latin American Congress on Biomedical Engineering CLAIB 2014, Paraná, Argentina 29, 30 & 31 October 2014. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-13117-7_217.

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Guo, Ya Ping, Bao Qiang Li, Yu Zhou, and De Chang Jia. "Effect of pH Values on Conversion of Calcite Crystals into Calcium Phosphate Phases in Buffer Solutions." In Key Engineering Materials. Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-456-1.2183.

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Joshi, Hardik, and Brajesh Kumar Jha. "A Mathematical Model to Study the Role of Buffer and ER Flux on Calcium Distribution in Nerve Cells." In Advances in Intelligent Systems and Computing. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-9953-8_23.

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Lefraich, H. "A 3D Fractional Step Computational Modeling of Nerve Impulse Transmission Through an Axonal Membrane: Incorporating Calcium Buffer and Extrusion." In Trends in Biomathematics: Chaos and Control in Epidemics, Ecosystems, and Cells. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-73241-7_20.

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Jha, Brajesh Kumar, and Hardik Joshi. "A Fractional Mathematical Model to Study the Effect of Buffer and Endoplasmic Reticulum on Cytosolic Calcium Concentration in Nerve Cells." In Fractional Calculus in Medical and Health Science. CRC Press, 2020. http://dx.doi.org/10.1201/9780429340567-8.

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Koch, Christof. "Diffusion, Buffering, and Binding." In Biophysics of Computation. Oxford University Press, 1998. http://dx.doi.org/10.1093/oso/9780195104912.003.0017.

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In Chap. 9 we introduced calcium ions and alluded to their crucial role in regulating the day-to-day life of neurons. The dynamics of the free intracellular calcium is controlled by a number of physical and chemical processes, foremost among them diffusion and binding to a host of different proteins, which serve as calcium buffers and as calcium sensors or triggers. Whereas buffers simply bind Ca2+ above some critical concentration, releasing it back into the cytoplasm when [Ca2+]i has been reduced below this level, certain proteins— such as calmodulin—change their conformation when they bind with Ca2+ ions, thereby activating or modulating enzymes, ionic channels, or other proteins. The calcium concentration inside the cell not only determines the degree of activation of calcium-dependent potassium currents but—much more importantly—is relevant for determining the changes in structure expressed in synaptic plasticity. As discussed in Chap. 13, it is these changes that are thought to underlie learning. Given the relevance of second messenger molecules, such as Ca2+, IP3, cyclic AMP and others, for the processes underlying growth, sensory adaptation, and the establishment and maintenance of synaptic plasticity, it is crucial that we have some understanding of the role that diffusion and chemical kinetics play in governing the behavior of these substances. Today, we have unprecedented access to the spatio-temporal dynamics of intracellular calcium in individual neurons using fluorescent calcium dyes, such as fura-2 or fluo-3, in combination with confocal or two-photon microscopy in the visible or in the infrared spectrum (Tsien, 1988; Tank et al., 1988; Hernández-Cruz, Sala, and Adams, 1990; Ghosh and Greenberg, 1995).
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Koch, Christof. "Unconventional Computing." In Biophysics of Computation. Oxford University Press, 1998. http://dx.doi.org/10.1093/oso/9780195104912.003.0026.

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As discussed in the introduction to this book, any (bio)physical mechanism that transforms some physical variable, such as the electrical potential across the membrane, in such a way that it can be mapped onto a meaningful formal mathematical operation, such as delayand- correlate or convolution, can be treated as a computation. Traditionally only Vm, spike trains, and the firing rate f(t) have been thought to play this role in the computations performed by the nervous system. Due to the recent and widespread usage of high-resolution calcium-dependent fluorescent dyes, the concentration of free intracellular calcium [Ca2+]i in presynaptic terminals, dendrites, and cell bodies has been promoted into the exalted rank of a variable that can act as a short-term memory and that can be manipulated using buffers, calcium-dependent enzymes, and diffusion in ways that can be said to instantiate specific computations. But why stop here? Why not consider the vast number of signaling molecules that are localized to specific intra- or extracellular compartments to instantiate specific computations that can act over particular spatial and temporal time scales? And what about the peptides and hormones that are released into large areas of the brain or that circulate in the bloodstream? In this penultimate chapter, we will acquaint the reader with several examples of computations that use such unconventional means. The computation in question constitutes a molecular switch that stores a few bits of information at each of the thousands of synapses on a typical cortical cell. In order to describe its principle of operation, it will be necessary to introduce the reader to some basic concepts in biochemistry. The ability of individual synapses to potentially store analog variables is important enough that this modest intellectual investment will pay off. (For an introduction to biochemistry, consult Stryer, 1995).
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"Does Calbindin-D28K Buffer Intracellular Free Calcium?" In Vitamin D. De Gruyter, 1994. http://dx.doi.org/10.1515/9783110882513-135.

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Conference papers on the topic "Calcium buffers"

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Qanz, P. R., E. S. Tackaberry, D. S. Palmer, B. Malchy, and G. Rock. "THE EFFECT OF CALCIUM ON THE STABILITY OF PURIFIED FACTOR VIII." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644037.

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The involvement of calcium and phospholipid in the activation of Factor X to Xa by Factor IXa and Factor VIII has been well documented. Although we and others have shown that maintenance of physiological concentrations of calcium has a positive effect on the stability of Factor VIII in plasma, calcium’s role in the structure and function of Factor VIII remains to be fully elucidated. To this end, we examined the effect of calcium on the stability of highly purified Factor VIII. Homogeneous Factor VIII (specific activity approximately 5,200 U/mg) was prepared from heparinized blood using a six-
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Rink, T. J. "CALCIUM IN PLATELET ACTIVATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644772.

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Studies with calcium ionophores, permeabilised platelets, and platelets containing fluorescent calcium indicators quin2 and fura-2 have shown that elevation [Ca2+]i is an effective trigger for shape-change, aggregation, secretion and release of TxA2; and that elevation of [Ca2+]i is an important part of a complex “activation cascade” set up by natural agonists combining with their surface receptors. We have used calcium ionophores to impose [Ca2+]i changes, monitored by indicator dyes, to construct [Ca2+]i/function relationships for shape-change, secretion, aggregation, arachidonic acid releas
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MAHENDRASINGAM, S., R. FETTIPLACE, and C. M. HACKNEY. "QUANTIFICATION OF CALCIUM BUFFERS IN VARIOUS SUBCELLULAR LOCATIONS IN RAT INNER AND OUTER HAIR CELLS." In Proceedings of the Ninth International Symposium. WORLD SCIENTIFIC, 2006. http://dx.doi.org/10.1142/9789812773456_0042.

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Procyk, R., and B. Blomback. "ROLE OF DISULFIDE BONDS NEAR THE CALCIUM BINDING SITES IN FIBRINOGEN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642939.

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Incubation of fibrinogen with 0.5 mM dithiothreitol in the presence of .20 mM calcium chloride cleaved disulfide bonds located at: the N-terminal end of the Aα-chain (either Aα28-Aα28 or Aα45-γ23), the C-terminal end of the Aα-chain (Aα442-Aα472) and the N-terminal end of the γ-chain (either of the symmetrical γ8, γ9 disulfides or the Aα45-γ23 disulfide bond). In the absence of calcium ions two additional disulfides, γ326-γ339, and one in the N-terminal end of the γ-chain were reduced.Plasmin digestion of the reduced fibrinogens in buffers containing calcium chloride produced fragments D and E
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Harrison, P., R. H. Saundry, and G. F. Savidge. "THE INFLUENCE OF L-LYSINE ON FACTOR VIII ELUTED FROM MATRIX BOUND DEXTRAN SULPHATE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644060.

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Factor VIII/vWF displays high affinity for matrix bound sulphate groups. Linear salt and pH gradient elution from Dextran Sulphate Sepharose at 4°C resulted in complete separation of the complex from major protein contaminants with typical yields of 70-90% vWF:Ag and vWF (RCoF). Elution in physiological calcium concentrations gave VIII and VIII:Ag yields of 35% and 65% respectively. Addition of L-Lysine (1.0M) to all buffers inhibited VIII/vWF binding, although lysine gradients (0-1.0M) gave comparable binding and elution profiles as C-1.0M NaCl, but with impaired resolution between protein mo
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Shih, Chien-Jen, Keith E. Forrester, and Wen-Bin Fan. "Application of Dry Chemical Stabilization Technology in Taiwan Kobin Bottom Ash Processing and Recycle Plant." In 14th Annual North American Waste-to-Energy Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/nawtec14-3191.

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The Taiwan Kobin Bottom Ash Processing &amp; Recycle Plant (Kobin-BAPRP) processes approximately one quarter million metric tons of bottom ashes from several municipal solid wastes the incinerators annually, generating fine aggregate finished products and ferrous recovery. The results from USEPA Method 1311 Toxicity Characteristic Leaching Procedure (TCLP) for un-treated bottom ash indicate that about 5% of the time that lead and less than 0.5% of the time, copper or cadmium may fail to meet leaching standards (i.e. 5 mg/L for Pb, 15 mg/L for Cu, and 1 mg/L for Cd ). Previously, Kobin applied
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Kaminski, M., and J. McDonagh. "CALCIUM-INDUCED FORMATION OF FIBRINOGEN -- FIBRIN COMPLEXES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643331.

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Presence of calcium chloride (8.3 mM) at u = 0.1 enhanced precipitate formation in several different fibrinogen preparations. The precipitate had gel like properties and demonstrated syneresls when disturbed. Precipitation proceeded in the time dependent manner with a plateau after 30 min. The amount of precipitate ranged from 4-24% of total protein content of different preparations. Precipitates did form at u = 0.1 without calcium ion; however, the amount of protein was 3 to 7 fold less than when calcium ion was present.SOS gel electrophoresis of calcium precipitates demonstrated cross-linkin
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Rao, Gundu H. R., and James G. White. "INFLUENCE OF CALCIUM FLUX ON STABILITY OF PLATELET MICROTUBULE COILS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643904.

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Resting human platelets have a characteristic discoid form supported by a circumferential microtubule (MT). Ultrastructural, immunocytochemical and immunofluorescence studies have shown that the circumferential MT is a stable structure which undergoes constriction following exposure of platelets to aggregating agents. However, some biochemical and morphological studies suggested that MT coils dissolved almost completely within seconds after exposure to aggregating agents, then reassembled 1-4 minutes later. One investigation suggested that disappearance of the MT coils was associated with calc
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KÖhlin, A., and J. Stenflo. "HIGH AFFINITY CALCIUM BINDING TO DOMAINES OF PROTEIN C THAT ARE HOMOLOGUS TO THE EPIDERMAL GROWTH FACTOR." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643645.

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In addition to γ-carboxyglutamic acid (Gla)-dependent calcium binding all of the vitamin K-dependent plasma proteins, except prothrombin, have one or two high affinity calcium binding sites that do not require the Gla residues. A common denominator among these proteins (factors IX, X, protein C, protein Z and protein S) is that they have domaines that are homologus to the epidermal growth factor (EGF) precursor. In factors VII,IX,X, protein C and in protein Z the aminoterminal of two EGF homology regions contain one residue of β-hydroxyaspartic acid (Hya) whereas in protein S the aminoterminal
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Cai, Wei-Jun, Jianzhong Su, Chaoying Ni, Jeremy Testa, and Ming Li. "Chesapeake Bay Acidification Buffered by Spatially-Separated Calcium Carbonate Mineral Formation and Dissolution." In Goldschmidt2020. Geochemical Society, 2020. http://dx.doi.org/10.46427/gold2020.307.

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