Log in

Relevant bibliographies by topics / Cam phaser / Journal articles

To see the other types of publications on this topic, follow the link: Cam phaser.

Journal articles on the topic 'Cam phaser'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Cam phaser.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Cheever Jr, Gordon, Charles Sullivan, Karl Schten, Ash Punater, and Clinton Erickson. "Design of an Electric Variable CAM Phaser Controller." SAE International Journal of Passenger Cars - Electronic and Electrical Systems 5, no. 2 (2012): 403–13. http://dx.doi.org/10.4271/2012-01-0433.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Andert, Jakob, Christian Sohn, Serge Klein, Andres Tönnesmann, Jens Oesterdiekhoff, and Michael Becker. "Influence of sensor and communication setup on electric cam phaser control quality." Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering 233, no. 3 (2018): 687–96. http://dx.doi.org/10.1177/0954407017746296.

Full text

Abstract:

This study investigates the control quality of an electric cam phaser system. The impact of different sensor concepts, synchronization algorithms, controller and hardware topologies on the control quality is examined by using a transient simulation covering the electric cam phaser, valve train, mechanical transmission and a wide variety of cam- and crankshaft trigger wheels. Limited angular accuracy effects are simulated by realistic sensor models and the processing of sensor signals by a real-time capable synchronization algorithm. Nonlinear friction in transmission and valve train are consid

APA, Harvard, Vancouver, ISO, and other styles

3

Babu, Numbury Surendra, and Didugu Jayaprakash. "Computational Study of the Stability of Tautomers and equilibrium constants of Cyanuric acid (CA) in Different solvents." JOURNAL OF ADVANCES IN CHEMISTRY 11, no. 2 (2015): 3485–97. http://dx.doi.org/10.24297/jac.v11i2.6691.

Full text

Abstract:

In the present investigation, the tautomeric and equilibrium of Cyanuric acid has been studied using Hartifock (HF) method in the gas phase and different solvents using the PCM model. The relative energies of these tautomers have been calculated at the HF level of theory using 6-311++ G (d,p) basis set. Energetics and relative stabilities of the tautomers were compared and analyzed in both the gaseous and different solvents. The results indicate that the keto tautomer (CA1) is the most stable form in the gas phase and other solvents. The order of stability of isomers was found to be CA1 > C

APA, Harvard, Vancouver, ISO, and other styles

4

Satyanarayana, P. S., Balasubramanian Loganathan, V. Lakshminarasimhan, A. Ramesh, and S. Sujatha. "Development of a Cam Phaser System to Improve the Performance of a Small Engine." SAE International Journal of Engines 8, no. 1 (2014): 250–57. http://dx.doi.org/10.4271/2014-32-0110.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Schett, G., M. J. Loza, A. Palanichamy, et al. "POS1036 COLLAGEN TURNOVER MARKERS ARE ASSOCIATED WITH ACTIVE PSORIATIC ARTHRITIS AND DECREASE WITH GUSELKUMAB TREATMENT IN A PHASE-3 CLINICAL TRIAL." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 790.2–792. http://dx.doi.org/10.1136/annrheumdis-2021-eular.779.

Full text

Abstract:

Background:Guselkumab (GUS), an interleukin-23p19-subunit monoclonal antibody, demonstrated efficacy compared to placebo (PBO) in reducing skin and musculoskeletal signs and symptoms in patients with active psoriatic arthritis (PsA) in two phase-3 studies, DISCOVER-1 & -2, and in retarding structural damage in DISCOVER-2.1,2Objectives:To evaluate tissue-derived extracellular matrix (ECM) products3,4 in serum of PsA patients in the DISCOVER-2 study and their relationship with radiographic damage, clinical response, and impact of treatment.Methods:In DISCOVER-2, patients were treated with GU

APA, Harvard, Vancouver, ISO, and other styles

6

Carr, Bruce A., Thomas M. Houlihan, and Michael A. Polini. "CAD/CAM in Phased Maintenance." Journal of Ship Production 7, no. 04 (1991): 234–47. http://dx.doi.org/10.5957/jsp.1991.7.4.234.

Full text

Abstract:

The authors' company is a medium-sized engineering company specializing in naval ship repair. The bulk of corporate work centers on the Phased Maintenance (PM) of three classes of ships. Typically, each PM contract covers three to five different ships per class scheduled for 90-day Availabilities at approximately one-year intervals over a period of five years. The type of work to be performed during each Phased Maintenance Availability (PMA) falls into one of two categories: ship alterations or ship repairs. The first group, ship alterations, is characterized by detailed, long-lead engineering

APA, Harvard, Vancouver, ISO, and other styles

7

Gilbert, M. R. "Calcium Vanadinite: An Alternative Apatite Host for Cl-rich Wastes." MRS Proceedings 1665 (2014): 319–24. http://dx.doi.org/10.1557/opl.2014.661.

Full text

Abstract:

ABSTRACTApatites are often seen as good potential candidates for the immobilization of halide-rich wastes and, in particular, chlorapatite (Ca5(PO4)3Cl) has received much attention in recent years. However, synthesis of chlorapatite waste-forms can produce a complicated multi-phase system, with a number of secondary phases forming, including β-TCP (Ca3(PO4)2), spodiosite (Ca2(PO4)Cl) and pyrophosphate (Ca2P2O7), many of which require elevated temperatures and extended calcinations times to reduce. Calcium vanadinite (Ca5(VO4)3Cl) demonstrates a much simpler phase system, with calcination at 75

APA, Harvard, Vancouver, ISO, and other styles

8

Jackers, Nastasia, Nathalie Maes, France Lambert, Adelin Albert, and Carole Charavet. "Standard vs computer-aided design/computer-aided manufacturing customized self-ligating systems using indirect bonding with both:." Angle Orthodontist 91, no. 1 (2020): 74–80. http://dx.doi.org/10.2319/012920-59.1.

Full text

Abstract:

ABSTRACT Objective To compare treatment duration and quality between standard vs computer-aided design/computer-aided manufacturing (CAD/CAM) customized self-ligating systems using indirect bonding with both. Materials and Methods This comparative trial included 24 patients: 12 treated with a CAD/CAM custom indirect bonding self-ligating system (CAD/CAM) and 12 others treated with an indirect bonding self-ligating standard system (I-STD). For each group, overall orthodontic treatment (OT) time was calculated and included the time needed to place each arch as well as the duration of the alignme

APA, Harvard, Vancouver, ISO, and other styles

9

Lin, Jiusheng, Henry van den Bedem, Axel T. Brunger, and Mark A. Wilson. "Atomic resolution experimental phase information reveals extensive disorder and bound 2-methyl-2,4-pentanediol in Ca2+-calmodulin." Acta Crystallographica Section D Structural Biology 72, no. 1 (2016): 83–92. http://dx.doi.org/10.1107/s2059798315021609.

Full text

Abstract:

Calmodulin (CaM) is the primary calcium signaling protein in eukaryotes and has been extensively studied using various biophysical techniques. Prior crystal structures have noted the presence of ambiguous electron density in both hydrophobic binding pockets of Ca2+-CaM, but no assignment of these features has been made. In addition, Ca2+-CaM samples many conformational substates in the crystal and accurately modeling the full range of this functionally important disorder is challenging. In order to characterize these features in a minimally biased manner, a 1.0 Å resolution single-wavelength a

APA, Harvard, Vancouver, ISO, and other styles

10

Kim, Dae Sung, and Jong Kook Lee. "Sintered Characteristics of 3 Mole% Yttria-Stabilized Zirconia Polycrystals (3Y-TZP) Implants Manufactured by Slip-Casting and Computer Aided Design/Computer Aided Manufacturing (CAD/CAM)." Journal of Nanoscience and Nanotechnology 21, no. 7 (2021): 3877–81. http://dx.doi.org/10.1166/jnn.2021.19203.

Full text

Abstract:

Two types of dense and toughened 3Y-TZP zirconia implants were fabricated by the sintering of green compacts. Then, the sintered properties of the two implants were compared. Slip-cast and post-sintered all-ceramic zirconia implants were fabricated by the heat treatment at 1450 °C for 2 h using optimal slurry conditions (60 wt% solid content, 1 wt% dispersant, and pH 12). Computer-aided design and manufacturing (CAD/CAM)-machined and post-sintered zirconia crowns, supplied by a dental hospital, were obtained by sintering at 1650 °C for 5 h. The X-ray diffraction results indicated that the phas

APA, Harvard, Vancouver, ISO, and other styles

11

Li, Wen Xu, Hua Zhao, Ying Song, Bin Su, and Fu Ping Wang. "Mechanical Properties of Machinable Zirconia Dental Composites." Key Engineering Materials 336-338 (April 2007): 1587–89. http://dx.doi.org/10.4028/www.scientific.net/kem.336-338.1587.

Full text

Abstract:

Ca3(PO4)2/ZrO2 dental composite ceramics using for CAD/CAM system were prepared and the effects of weak phases on microstructures and mechanical properties were studied. The results showed that intergranular spreads happened with the increasing Ca3(PO4)2 contents due to the discontinuity of weak interfaces between Zirconia and Calcium phosphate in matrix. So the flexural strength and hardness of the Ca3(PO4)2/ZrO2 composite ceramics were decreased effectively, which improved the machinability of the composites. On the other hand, strong interfaces between Zirconias increased the integrality of

APA, Harvard, Vancouver, ISO, and other styles

12

Muhamad Bustaman, Nurul Wahieda, and Mohd Salman Abu Mansor. "A Study on CAD/CAM Application in CNC Milling Using Industrial Clay." Applied Mechanics and Materials 761 (May 2015): 32–36. http://dx.doi.org/10.4028/www.scientific.net/amm.761.32.

Full text

Abstract:

Throughout the production process, improper planning and exploitation of the CAD/CAM system leads to the low level utilization of the CNC milling machine. In product design, tangible prototype is fabricated using CAD/CAM techniques in the design phase to analyse and modify the product before actual production. In this research, industrial clay is used as the prototype material. The objectives of the study are to investigate the machining parameters of industrial clay using the CNC milling machine and to apply the CAD/CAM system in producing a clay sample part via the CNC milling machine. Using

APA, Harvard, Vancouver, ISO, and other styles

13

Sarabia-Pérez, Rubén, Antonio Jimeno-Morenilla, and Rafael Molina-Carmona. "Deterministic mathematical morphology for CAD/CAM." Engineering Computations 31, no. 7 (2014): 1221–41. http://dx.doi.org/10.1108/ec-02-2013-0056.

Full text

Abstract:

Purpose – The purpose of this paper is to present a new geometric model based on the mathematical morphology paradigm, specialized to provide determinism to the classic morphological operations. The determinism is needed to model dynamic processes that require an order of application, as is the case for designing and manufacturing objects in CAD/CAM environments. Design/methodology/approach – The basic trajectory-based operation is the basis of the proposed morphological specialization. This operation allows the definition of morphological operators that obtain sequentially ordered sets of poi

APA, Harvard, Vancouver, ISO, and other styles

14

Ruder, G. K. "CAD CAM trans-tibial temporary prosthesis: Analysis and comparison with an established technique." Prosthetics and Orthotics International 16, no. 3 (1992): 189–95. http://dx.doi.org/10.3109/03093649209164339.

Full text

Abstract:

The purpose of this study was to evaluate the application of CAD CAM in the production of temporary trans-tibial prostheses. The CAD CAM system was assessed based on the number of socket attempts, number of prosthetic appointments, and temporary prosthesis rehabilitation time. These parameters were considered to be related to the quality of socket fit and were influenced by the entire interdisciplinary team including the patient. A concurrent prospective comparison between the CAD CAM system and an established fibreglass/pelite liner technique was also performed. Patients (n=30), were fitted w

APA, Harvard, Vancouver, ISO, and other styles

15

Kwon, Soon-Yong, Yong Kim, Hyo-Won Ahn, Ki-Beom Kim, Kyu-Rhim Chung, and Seong-Hun Kim (Sunny). "Computer-Aided Designing and Manufacturing of Lingual Fixed Orthodontic Appliance Using 2D/3D Registration Software and Rapid Prototyping." International Journal of Dentistry 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/164164.

Full text

Abstract:

The availability of 3D dental model scanning technology, combined with the ability to register CBCT data with digital models, has enabled the fabrication of orthognathic surgical CAD/CAM designed splints, customized brackets, and indirect bonding systems. In this study, custom lingual orthodontic appliances were virtually designed by merging 3D model images with lateral and posterior-anterior cephalograms. By exporting design information to 3D CAD software, we have produced a stereolithographic prototype and converted it into a cobalt-chrome alloy appliance as a way of combining traditional pr

APA, Harvard, Vancouver, ISO, and other styles

16

BREDESTON, Luis M., and Alcides F. REGA. "Pre-steady-state phosphorylation and dephosphorylation of detergent-purified plasma-membrane Ca2+-ATPase." Biochemical Journal 361, no. 2 (2002): 355–61. http://dx.doi.org/10.1042/bj3610355.

Full text

Abstract:

Pre-steady-state phosphorylation and dephosphorylation of purified and phospholipid-depleted plasma-membrane Ca2+-ATPase (PMCA) solubilized in the detergent polyoxyethylene 10 lauryl ether were studied at 25°C. The time course of phosphorylation with ATP of the enzyme associated with Ca2+, probably the true phosphorylation reaction, showed a fast phase (kapp near 400s−1) followed by a slow phase (kapp = 23s−1). With asolectin or acidic phosphatidylinositol, the concentration of phosphoenzyme (EP) increased at as high a rate as before, passed through a maximum at 4ms and stabilized at a steady

APA, Harvard, Vancouver, ISO, and other styles

17

Volk, T., and B. Geiger. "A-CAM: a 135-kD receptor of intercellular adherens junctions. I. Immunoelectron microscopic localization and biochemical studies." Journal of Cell Biology 103, no. 4 (1986): 1441–50. http://dx.doi.org/10.1083/jcb.103.4.1441.

Full text

Abstract:

The recently described adherens junction-specific 135-kD protein (Volk, T., and B. Geiger, 1984, EMBO (Eur. Mol. Biol. Organ.) J., 3:2249-2260) was localized along cardiac muscle intercalated discs by immunogold labeling of ultrathin frozen sections. Analysis of this labeling indicated that the 135-kD protein, adherens junction-specific cell adhesion molecule (A-CAM), is tightly associated with the plasma membrane unlike vinculin labeling, which was present along the membrane-bound plaques of the fascia adherens. In cultured chick lens cells, A-CAM was associated with Ca2+-dependent junctions

APA, Harvard, Vancouver, ISO, and other styles

18

Easom, Richard A., Natalie R. Filler, Emma M. Ings, Jim Tarpley, and Michael Landt. "Correlation of the Activation of Ca2+/Calmodulin-Dependent Protein Kinase II with the Initiation of Insulin Secretion from Perifused Pancreatic Islets*." Endocrinology 138, no. 6 (1997): 2359–64. http://dx.doi.org/10.1210/endo.138.6.5179.

Full text

Abstract:

Abstract An experimental procedure has been designed to permit the simultaneous assessment of the activation status of the multifunctional Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) with insulin secretion in perifused islets. By this procedure, the activation of CaM kinase II by glucose correlated closely with the initial and sustained phases of insulin secretion within a 30-min test period. By contrast, islets (160–200/tube) in static incubations neither supported second-phase insulin secretion nor CaM kinase II activation beyond 10–15 min. This was not the result of the accu

APA, Harvard, Vancouver, ISO, and other styles

19

Son, Myeong-Jo, Jeong-Youl Lee, Ho Gyun Park, Jong-Oh Kim, Jengjae Woo, and JoungHyun Lee. "Development of 3D CAD/CAE Interface in Initial Structural Design Phase of Shipbuilding." Korean Journal of Computational Design and Engineering 21, no. 2 (2016): 186–95. http://dx.doi.org/10.7315/cadcam.2016.186.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Charrier, Maxime, Olivier Rascle, David Le Foll, and Geneviève Cabagno. "Faut-il se confronter à meilleur que soi ? Effets de l’intensité de la comparaison sociale ascendante sur l’évaluation de soi et la performance motrice." Movement & Sport Sciences - Science & Motricité, no. 112 (2021): 1–9. http://dx.doi.org/10.1051/sm/2021009.

Full text

Abstract:

L’objectif de cette étude était d’observer l’influence de l’intensité d’un feedback de comparaison sociale ascendante sur l’évaluation de soi et la performance motrice d’élèves français lors d’une tâche d’équilibre. L’étude s’est déroulée en deux phases. La première était consacrée à la sélection des cibles de comparaison. Les participants, 76 élèves, 31 filles et 45 garçons (Mâge = 12,7 ans), devaient mentionner le nom des élèves avec lesquels ils avaient l’habitude de se comparer en éducation physique et sportive. Trois semaines plus tard, 35 élèves garçons (Mâge = 12,8 ans) ont participé à

APA, Harvard, Vancouver, ISO, and other styles

21

Volk, T., and B. Geiger. "A-CAM: a 135-kD receptor of intercellular adherens junctions. II. Antibody-mediated modulation of junction formation." Journal of Cell Biology 103, no. 4 (1986): 1451–64. http://dx.doi.org/10.1083/jcb.103.4.1451.

Full text

Abstract:

Intercellular adherens junctions between cultured lens epithelial cells are highly Ca2+-dependent and are readily dissociated upon chelation of extracellular Ca2+ ions. Addition of Ca2+ to EGTA-treated cells results in the recovery of cell-cell junctions including the reorganization of adherens junction-specific cell adhesion molecule (A-CAM), vinculin, and actin (Volk, T., and B. Geiger, 1986, J. Cell Biol., 103:000-000). Incubation of cells during the recovery phase with Fab' fragments of anti-A-CAM specifically inhibited the re-formation of cell-cell adherens junctions. This inhibition was

APA, Harvard, Vancouver, ISO, and other styles

22

Mortensen, J., B. Feagan, A. C. Bay-Jensen, et al. "P516 Serological biomarkers of tissue remodeling are associated with endoscopic remission in Crohn’s disease patients treated with GED-0301 (mongersen)." Journal of Crohn's and Colitis 15, Supplement_1 (2021): S494—S495. http://dx.doi.org/10.1093/ecco-jcc/jjab076.638.

Full text

Abstract:

Abstract Background In Crohn’s disease (CD) Smad7 is overexpressed in the intestinal mucosa, where it contributes to a sustained production of inflammatory cytokines, increased matrix metalloproteinase (MMP) activity and chronic inflammation through inhibition of the anti-inflammatory actions of TGF-beta. GED-0301, an anti-sense oligodeoxynucleaotide complementary to the mRNA of Smad7, inhibits the translation and synthesis of the Smad7 protein. We investigated exploratory biomarkers of collagen degradation by MMPs (C1M, C3M, C4M) and collagen formation (PRO-C3, PRO-C4 and PRO-C5) and their as

APA, Harvard, Vancouver, ISO, and other styles

23

Koenig, Andreas, Julius Schmidtke, Leonie Schmohl, et al. "Characterisation of the Filler Fraction in CAD/CAM Resin-Based Composites." Materials 14, no. 8 (2021): 1986. http://dx.doi.org/10.3390/ma14081986.

Full text

Abstract:

The performance of dental resin-based composites (RBCs) heavily depends on the characteristic properties of the individual filler fraction. As specific information regarding the properties of the filler fraction is often missing, the current study aims to characterize the filler fractions of several contemporary computer-aided design/computer-aided manufacturing (CAD/CAM) RBCs from a material science point of view. The filler fractions of seven commercially available CAD/CAM RBCs featuring different translucency variants were analysed using Scanning Electron Microscopy (SEM) with Energy Disper

APA, Harvard, Vancouver, ISO, and other styles

24

Kuckreja, Harinder, and K. Kuckreja. "CAD-CAM Implant Abutments-A Solution for Challenging Clinical Cases." Dental Journal of Advance Studies 03, no. 03 (2015): 124–28. http://dx.doi.org/10.1055/s-0038-1672026.

Full text

Abstract:

AbstractDue to the success of osseointegration and improved surgical protocols, implant placement has become a routine practice in most of the dental clinics. The latest developments focus on the implant superstructure and prosthodontic phase. In digitally driven world, use of virtually designed and milled implant abutments is growing exponentially. More and more dentists are going in for customised milled abutments for predicable soft tissue contours and esthetics. The present article discusses about the restorative options for a few clinical situations where custom milled abutments seemed a

APA, Harvard, Vancouver, ISO, and other styles

25

Amaral, Michelle D., and Lucas Pozzo-Miller. "Intracellular Ca2+Stores and Ca2+Influx Are Both Required for BDNF to Rapidly Increase Quantal Vesicular Transmitter Release." Neural Plasticity 2012 (2012): 1–10. http://dx.doi.org/10.1155/2012/203536.

Full text

Abstract:

Brain-derived neurotrophic factor (BDNF) is well known as a survival factor during brain development as well as a regulator of adult synaptic plasticity. One potential mechanism to initiate BDNF actions is through its modulation of quantal presynaptic transmitter release. In response to local BDNF application to CA1 pyramidal neurons, the frequency of miniature excitatory postsynaptic currents (mEPSC) increased significantly within 30 seconds; mEPSC amplitude and kinetics were unchanged. This effect was mediated via TrkB receptor activation and required both full intracellular Ca2+stores as we

APA, Harvard, Vancouver, ISO, and other styles

26

Chang, Shao-Han, Ying Hao Yu, Alan He, Chen Yin Ou, Bai Chuang Shyu, and Andrew Chih Wei Huang. "BDNF Protein and BDNF mRNA Expression of the Medial Prefrontal Cortex, Amygdala, and Hippocampus during Situational Reminder in the PTSD Animal Model." Behavioural Neurology 2021 (March 8, 2021): 1–13. http://dx.doi.org/10.1155/2021/6657716.

Full text

Abstract:

Whether BDNF protein and BDNF mRNA expression of the medial prefrontal cortex (mPFC; cingulated cortex area 1 (Cg1), prelimbic cortex (PrL), and infralimbic cortex (IL)), amygdala, and hippocampus (CA1, CA2, CA3, and dentate gyrus (DG)) was involved in fear of posttraumatic stress disorder (PTSD) during the situational reminder of traumatic memory remains uncertain. Footshock rats experienced an inescapable footshock (3 mA, 10 s), and later we have measured fear behavior for 2 min in the footshock environment on the situational reminder phase. In the final retrieval of situational reminder, BD

APA, Harvard, Vancouver, ISO, and other styles

27

Santos, C., Carlos Nelson Elias, Andréa Matos Melo, and Sérgio Neves Monteiro. "Zirconia Blocks Properties Used for CAD/CAM Dentistry Restorations." Materials Science Forum 727-728 (August 2012): 804–8. http://dx.doi.org/10.4028/www.scientific.net/msf.727-728.804.

Full text

Abstract:

Several CAD/CAM systems are available to dental prosthesis laboratories that can be used to make all-ceramic copings and frameworks. In Brazil, the use of these systems presents low demand, due principally the high blocks ceramics cost used for theses systems. The ceramic blocks are imported. To increase the dental ceramic CAD/CAM applications is necessary develop and produce the ceramics blocks in Brazil. The purpose of the present work is to compare the mechanical properties of blocks of zirconium developed in the Brazil (ProtMat® Co) and imported (VITA). It was determined the mechanical and

APA, Harvard, Vancouver, ISO, and other styles

28

Adams, Denise, Courtney Spelliscy, Leka Sivakumar, et al. "CAM and Pediatric Oncology: Where Are All the Best Cases?" Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/632351.

Full text

Abstract:

Background. Use of complementary and alternative medicine (CAM) by children with cancer is high; however, pediatric best cases are rare.Objectives. To investigate whether best cases exist in pediatric oncology using a three-phase approach and to compare our methods with other such programs.Methods. In phase I, Children’s Oncology Group (COG) oncologists were approached via email and asked to recall patients who were (i) under 18 when diagnosed with cancer, (ii) diagnosed between 1990 and 2006, (iii) had unexpectedly positive clinical outcome, and (iv) reported using CAM during or after cancer

APA, Harvard, Vancouver, ISO, and other styles

29

Kahl, Christina R., and Anthony R. Means. "Calcineurin Regulates Cyclin D1 Accumulation in Growth-stimulated Fibroblasts." Molecular Biology of the Cell 15, no. 4 (2004): 1833–42. http://dx.doi.org/10.1091/mbc.e03-10-0730.

Full text

Abstract:

Calcium (Ca2+) and calmodulin (CaM) are required for progression of mammalian cells from quiescence into S phase. In multiple cell types, cyclosporin A causes a G1 cell cycle arrest, implicating the serine/threonine phosphatase calcineurin as one Ca2+/CaM-dependent enzyme required for G1 transit. Here, we show, in diploid human fibroblasts, that cyclosporin A arrested cells in G1 before cyclin D/cdk4 complex activation and retinoblastoma hyperphosphorylation. This arrest occurred in early G1 with low levels of cyclin D1 protein. Because cyclin D1 mRNA was induced normally in the cyclosporin A-

APA, Harvard, Vancouver, ISO, and other styles

30

Bidra, Avinash S. "The 2-Visit CAD-CAM Implant-Retained Overdenture: A Clinical Report." Journal of Oral Implantology 40, no. 6 (2014): 722–28. http://dx.doi.org/10.1563/aaid-joi-d-12-00237.

Full text

Abstract:

Recently, computer-aided technology has become commercially available in the United States for fabrication of complete dentures. Manufacturers offering this technology require exclusive clinical and laboratory protocols that sharply contrast with the traditional paradigms of complete denture therapy. These protocols allow fabrication of complete dentures in only 2 clinical appointments. Currently, there are no clinical reports in the scientific literature describing the use of this technology for overdentures. This article describes the successful use of computer aided design-computer aided ma

APA, Harvard, Vancouver, ISO, and other styles

31

Nestorovic, Miodrag, Predrag Nestorovic, and Jelena Milosevic. "Performance based approach in design of freeform space structures." Facta universitatis - series: Architecture and Civil Engineering 15, no. 2 (2017): 153–66. http://dx.doi.org/10.2298/fuace160404011n.

Full text

Abstract:

This paper is related to the fact that use of computational tools for form generation, analysis and digital fabrication (CAD/CAM/CAE) in an efficient way enables accurate representation of ideas, simulation of diverse impact and production of rational design solutions. Application of geometrical and numerical computational methods and adoption of performance based priorities enables formal exploration in constrained conditions and improvement of architectural engineering design process. Implementation of advanced technologies in 3D digital design process facilitates production of unconventiona

APA, Harvard, Vancouver, ISO, and other styles

32

Willumsen, Nicholas, Kim Leitzel, Suhail M. Ali, et al. "Extracellular matrix (ECM) protein fragments in serum and outcomes in two metastatic breast cancer cohorts." Journal of Clinical Oncology 35, no. 15_suppl (2017): 1085. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.1085.

Full text

Abstract:

1085 Background: Extracellular matrix (ECM) is the non-cellular component of all tissues. Increased ECM formation and matrix metallo-protease (MMP) mediated ECM degradation are parts of tumorgenesis. The altered ECM remodeling generates specific ECM fragments that are released into the circulation. We evaluated the association of specific ECM/collagen fragments measured in serum with outcomes in two independent metastatic breast cancer (MBC) cohorts. Methods: C1M (MMP-degraded type I collagen), C3M (MMP-degraded type III collagen), C4M (MMP-degraded type IV collagen), and PRO-C3 (pro-peptide r

APA, Harvard, Vancouver, ISO, and other styles

33

Li, Linying, Owen Im, Ashutosh Chilkoti, and Gabriel P. López. "Encapsulation of Stimuli-Responsive Fusion Proteins in Silica: Thermally Responsive Metal Ion-Sensitive Hybrid Membranes." MRS Proceedings 1498 (2013): 169–75. http://dx.doi.org/10.1557/opl.2013.332.

Full text

Abstract:

ABSTRACTIn this study, we demonstrate the fabrication of hybrid membranes that exhibit discrete and reversible changes in permeability in response to changes in calcium ion (Ca2+) concentration and temperature. Fusion proteins comprising calmodulin (CAM) and elastin-like polypeptides (ELPs) were used as stimuli-responsive elements due to their ability to undergo a reversible lower critical solution temperature (LCST) phase transition, which is sensitive to Ca2+ binding. The calmodulin elastin-like polypeptides fusions (CAM-ELPs) were incorporated into polymerizing silica networks using a simpl

APA, Harvard, Vancouver, ISO, and other styles

34

Sakuma, Satoru, Daisuke Tokuhara, Hiroshi Otsubo, Tsunekazu Yamano та Haruo Shintaku. "Dynamic Change in Cells Expressing IL-1β in Rat Hippocampus after Status Epilepticus". Japanese Clinical Medicine 5 (січень 2014): JCM.S13738. http://dx.doi.org/10.4137/jcm.s13738.

Full text

Abstract:

Background The time course of cytokine dynamics after seizure remains controversial. Here we evaluated the changes in the levels and sites of interleukin (IL)-1β expression over time in the hippocampus after seizure. Methods Status epilepticus (SE) was induced in adult Wistar rats by means of intraperitoneal injection of kainic acid (KA). Subsequently, the time courses of cellular localization and IL-1β concentration in the hippocampus were evaluated by means of immunohistochemical and quantitative assays. Results On day 1 after SE, CA3 pyramidal cells showed degeneration and increased IL-1β e

APA, Harvard, Vancouver, ISO, and other styles

35

D’Amico, Moreno, Edyta Kinel, Piero Roncoletta, et al. "Data-driven CAD-CAM vs traditional total contact custom insoles: A novel quantitative-statistical framework for the evaluation of insoles offloading performance in diabetic foot." PLOS ONE 16, no. 3 (2021): e0247915. http://dx.doi.org/10.1371/journal.pone.0247915.

Full text

Abstract:

Background Elevated plantar pressures represent a significant risk factor for neuropathic diabetic foot (NDF) ulceration. Foot offloading, through custom-made insoles, is essential for prevention and healing of NDF ulcerations. Objective quantitative evaluation to design custom-made insoles is not a standard method. Aims: 1) to develop a novel quantitative-statistical framework (QSF) for the evaluation and design of the insoles’ offloading performance through in-shoe pressure measurement; 2) to compare the pressure-relieving efficiency of traditional shape-based total contact customised insole

APA, Harvard, Vancouver, ISO, and other styles

36

Resende, TH, KR Reis, LH Schlichting, and P. Magne. "Ultrathin CAD-CAM Ceramic Occlusal Veneers and Anterior Bilaminar Veneers for the Treatment of Moderate Dental Biocorrosion: A 1.5-Year Follow-Up." Operative Dentistry 43, no. 4 (2018): 337–46. http://dx.doi.org/10.2341/17-007-t.

Full text

Abstract:

SUMMARY Dental biocorrosion can produce a devastating impact on oral health. The restorative phase of the treatment should not cause additional damage of the remaining sound tooth structure. Ultrathin occlusal veneers are a conservative alternative to traditional onlays and complete crowns for the treatment of severe biocorrosive lesions. This strategy is explained in the present case report through a full-mouth rehabilitation of a patient with moderate biocorrosion. Maxillary anterior teeth were restored using the bilaminar technique (lingual direct composite veneers with labial ceramic venee

APA, Harvard, Vancouver, ISO, and other styles

37

dos Santos, Claudinei, Felipe Antunes Santos, and Carlos Nelson Elias. "Properties of Nanostructured 3Y-TZP Blocks Used for CAD/CAM Dental Restoration." Key Engineering Materials 396-398 (October 2008): 603–6. http://dx.doi.org/10.4028/www.scientific.net/kem.396-398.603.

Full text

Abstract:

Several CAD/CAM systems are available to dental prosthesis laboratories which can be used to fabricate all-ceramic copings and frameworks. The use of these systems presents low demand, due principally the high blocks ceramics cost used for theses systems. Usually, these ceramic blocks are sintered at high temperatures, between 1450 and 15500C, resulting in micrometric ZrO2 microstructure. A considerable innovation in these ceramics systems used in CAD/CAM applications was introduced by the use of nanometric-tetragonal ZrO2 blocks, which are sintered at low sintering temperatures resulting in n

APA, Harvard, Vancouver, ISO, and other styles

38

Song, Jun Ho, Young Jin Jo, Hee Gon Bang, and Sang Yeup Park. "Abnormal Grain Growth Mechanism of Calcium Hexaluminate Phase." Materials Science Forum 534-536 (January 2007): 485–88. http://dx.doi.org/10.4028/www.scientific.net/msf.534-536.485.

Full text

Abstract:

Calcium-hexaluminate phase(CA6) phase is known to be effective for the crack shielding due to the spinel block crystal structure. In this study, we focused to control the CA6 morphology for the good damage tolerance behavior in alumina and zirconia/calcium-hexaluminate(CA6) composites. calcium-hexaluminate(CA6) composites were prepared from zirconia, alumina and calcium carbornate powders. Calcium-hexaluminate(CA6) phase was obtained by the solid reaction through the formation of intermediate phase(CA2). CA6 phase showed column type abnormal grain grown behavior composed of small blocks. Due t

APA, Harvard, Vancouver, ISO, and other styles

39

Xiu, Mei Hong, XiaoE Lang, Da Chun Chen, et al. "Cognitive Deficits and Clinical Symptoms with Hippocampal Subfields in First-Episode and Never-Treated Patients with Schizophrenia." Cerebral Cortex 31, no. 1 (2020): 89–96. http://dx.doi.org/10.1093/cercor/bhaa208.

Full text

Abstract:

Abstract Memory dysfunction and associated hippocampal disturbances play crucial roles in cognitive impairment of schizophrenia. To examine the relationships between cognitive function and the hippocampal subfields (HSs) in first-episode never-treated (FENT) schizophrenia patients, the HSs were segmented in 39 FENT patients and 30 healthy controls using a state-of the-art automated algorithm. We found no significant differences in any HSs between the patients and controls. However, multivariate regression analysis showed that the left cornu ammonis 1 (CA1), left hippocampal tail, left presubic

APA, Harvard, Vancouver, ISO, and other styles

40

Kruszewski, F. H., H. Hennings, S. H. Yuspa, and R. W. Tucker. "Regulation of intracellular free calcium in normal murine keratinocytes." American Journal of Physiology-Cell Physiology 261, no. 5 (1991): C767—C773. http://dx.doi.org/10.1152/ajpcell.1991.261.5.c767.

Full text

Abstract:

Cultured normal murine keratinocytes maintain a basal cell phenotype in medium with a Ca2+ concentration of 0.05 mM and differentiate when exposed for 28-48 h to medium supplemented with extracellular Ca2+ greater than 0.10 mM. Previous studies have documented Ca2+ activation of signaling pathways in the plasma membrane and tightly regulated cellular responses to small incremental changes in extracellular Ca2+. To determine if changes in free cytosolic calcium (Cai) are associated with these early signaling events, digital image analysis of fura-2-loaded keratinocytes was used to measure Cai i

APA, Harvard, Vancouver, ISO, and other styles

41

Schöttler, Mark Aurel, Helmut Kirchhoff, Engelbert Weis, and Katharina Siebke. "Metabolic control of photosynthetic electron transport in crassulacean acid metabolism-induced Mesembryanthemum crystallinum." Functional Plant Biology 29, no. 6 (2002): 697. http://dx.doi.org/10.1071/pp01222.

Full text

Abstract:

This paper originates from a presentation at the IIIrd International Congress on Crassulacean Acid Metabolism, Cape Tribulation, Queensland, Australia, August 2001. We investigated photosynthetic electron transport in leaves of the facultative crassulacean acid metabolism (CAM) plant Mesembryanthemum crystallinum L. After CAM induction, electron transport exhibited variable redox kinetics during the diurnal CAM cycle. In CAM Phase IV, most of PSI (P700) and chlorophyll a fluorescence relaxed with a halftime of 20 ms after a saturating light pulse. This time-constant may reflect the overall lin

APA, Harvard, Vancouver, ISO, and other styles

42

D’Albis, Tiziano, Jorge Jaramillo, Henning Sprekeler, and Richard Kempter. "Inheritance of Hippocampal Place Fields Through Hebbian Learning: Effects of Theta Modulation and Phase Precession on Structure Formation." Neural Computation 27, no. 8 (2015): 1624–72. http://dx.doi.org/10.1162/neco_a_00752.

Full text

Abstract:

A place cell is a neuron that fires whenever the animal traverses a particular location of the environment—the place field of the cell. Place cells are found in two regions of the rodent hippocampus: CA3 and CA1. Motivated by the anatomical connectivity between these two regions and by the evidence for synaptic plasticity at these connections, we study how a place field in CA1 can be inherited from an upstream region such as CA3 through a Hebbian learning rule, in particular, through spike-timing-dependent plasticity (STDP). To this end, we model a population of CA3 place cells projecting to a

APA, Harvard, Vancouver, ISO, and other styles

43

Monková, Katarína, Peter Monka, Matej Somsak, and Andrej Andrej. "The Principles of Fixtures Design and their Application at Virtual Modelling in CAD/CAM System." Applied Mechanics and Materials 718 (December 2014): 99–104. http://dx.doi.org/10.4028/www.scientific.net/amm.718.99.

Full text

Abstract:

The article deals with the principles of fixtures design and their application at virtual modelling in CAD/CAM system. The computers have became an important part of our life and about its benefits nobody doubts. The designers have got the strong tools into the development hands that use the potential of computer techniques for the creation of completely new applications, which alleviate the solution not only of common problems, but already the special defined, too. New technologies bring the change of mind. The classic way “production on the base of drawing” is often substituted by computer a

APA, Harvard, Vancouver, ISO, and other styles

44

Yu, Lifeng, Jianjun Xu, Etsuko Minobe, et al. "Role of protein phosphatases in the run down of guinea pig cardiac Cav1.2 Ca2+ channels." American Journal of Physiology-Cell Physiology 310, no. 10 (2016): C773—C779. http://dx.doi.org/10.1152/ajpcell.00199.2015.

Full text

Abstract:

This study aimed to investigate protein phosphatases involved in the run down of Cav1.2 Ca2+ channels. Single ventricular myocytes obtained from adult guinea pig hearts were used to record Ca2+ channel currents with the patch-clamp technique. Calmodulin (CaM) and ATP were used to restore channel activity in inside-out patches. Inhibitors of protein phosphatases were applied to investigate the role of phosphatases. The specific protein phosphatase type 1 (PP1) inhibitor (PP1 inhibitor-2) and protein phosphatase type 2A (PP2A) inhibitor (fostriecin) abolished the slow run down of Cav1.2 Ca2+ cha

APA, Harvard, Vancouver, ISO, and other styles

45

Traynelis, S. F., and R. Dingledine. "Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice." Journal of Neurophysiology 59, no. 1 (1988): 259–76. http://dx.doi.org/10.1152/jn.1988.59.1.259.

Full text

Abstract:

1. The CA1 region of rat hippocampal slices bathed in 8.5 mM interstitial K+ ([K+]o) exhibited spontaneous 20- to 90-s electrographic seizures at regular intervals of 1–8 min. In these same slices CA3 neurons generated spontaneous interictal bursts that propagated throughout the pyramidal cell subfields. CA1 electrographic seizures contained components reminiscent of discharges recorded in vivo during tonic-clonic motor seizures. The tonic phase lasted 1–10 s, consisted of a sustained depolarization and firing of CA1 pyramidal cells, and was associated with a negative extracellular potential i

APA, Harvard, Vancouver, ISO, and other styles

46

Stefanovsky, Sergey V., Olga I. Stefanovsky, and Ivan L. Prusakov. "Nagelschmidtite as a candidate host phase for actinides, rare earth and different waste elements." MRS Advances 3, no. 20 (2017): 1073–83. http://dx.doi.org/10.1557/adv.2017.614.

Full text

Abstract:

AbstractNagelschmidtite, Ca7P2Si2O16, is an end-member of continuous solid solution Ca2SiO4 – Ca3(PO4)2⋅2Ca2SiO4 within the pseudo-binary system Ca3(PO4)2 – Ca2SiO4 (whitlockite – larnite). This phase is capable to wide isomorphic exchanges in Ca, P and Si sites: Ca2+ = Sr2+; Ca2+ = Eu2+; Ca2+ + P5+ = (RE,An)3+ + Si4+, 2Ca2+ = Na+ + (RE,An)3+; 2Ca2+ = An4+ + ☐; Ca2+ + Si4+ = (RE,An)3+ + (Al,Fe)3+; Ca2+ + Si4+ = Na+ + P5+; 2Ca2+ = Na+ + (Al,Fe)3+; Ca2+ + P5+ = Na+ + S6+. It was found in metallurgical slags and geological formations. We revealed nagelschmidtite-type phase in vitrified phosphorus

APA, Harvard, Vancouver, ISO, and other styles

47

Tanaka, E., H. Uchikado, S. Niiyama, K. Uematsu, and H. Higashi. "Extrusion of Intracellular Calcium Ion After In Vitro Ischemia in the Rat Hippocampal CA1 Region." Journal of Neurophysiology 88, no. 2 (2002): 879–87. http://dx.doi.org/10.1152/jn.2002.88.2.879.

Full text

Abstract:

Simultaneous recordings of intracellular Ca2+([Ca2+]i) signal and extracellular DC potential were obtained from the CA1 region in 1-[6-amino-2-(5-carboxy-2-oxazolyl)-5-benzofuranyloxy]-2-(2-amino-5-methylphenoxy)-ethane- N, N, N′, N′-tetraacetic acid penta-acetoxymethyl ester (Fura-2/AM)-loaded rat hippocampal slices. Superfusion with oxygen- and glucose-deprived medium (in vitro ischemia) for 5–6 min produced a rapid rise of the [Ca2+]i level in the stratum radiatum (rising phase of the [Ca2+]i signal), which occurred simultaneously with a rapid negative DC potential (rapid negative potential

APA, Harvard, Vancouver, ISO, and other styles

48

Queiroz, Carlos M., Maria Helena F. V. Fernandes, and Jorge R. Frade. "Isothermal Crystallisation of a Glass from the 3CaO.P₂O₅–SiO₂–MgO–K₂O System Studied by Impedance Spectroscopy." Materials Science Forum 514-516 (May 2006): 1073–77. http://dx.doi.org/10.4028/www.scientific.net/msf.514-516.1073.

Full text

Abstract:

Impedance spectroscopy was used to measure the changes of electrical properties during the isothermal crystallisation of the phosphate phase in bulk samples of a glass with nominal molar composition (3CaO.P2O5)20(SiO2)35(MgO)38.354(K2O)6.646, developed for biomedical applications. Crystallization studies were performed in isothermal conditions at 800°C and 860°C, and were monitored by impedance spectroscopy. XRD shows that a stable orthophosphate phase, Ca9MgK(PO4)7 crystallizes at about 860°C, after formation of earlier phosphate precursors formed at lower temperatures, namely oxyapatite (Ca5

APA, Harvard, Vancouver, ISO, and other styles

49

Kitazawa, Toshio, Toshiyasu Matsui, Shuichi Katsuki та ін. "A temporal Ca2+ desensitization of myosin light chain kinase in phasic smooth muscles induced by CaMKKβ/PP2A pathways". American Journal of Physiology-Cell Physiology 321, № 3 (2021): C549—C558. http://dx.doi.org/10.1152/ajpcell.00136.2021.

Full text

Abstract:

Cell signaling pathways regulating myosin regulatory light chain (LC20) phosphorylation contribute to determining contractile responses in smooth muscles. Following excitation and contraction, phasic smooth muscles, such as the digestive tract and urinary bladder, undergo relaxation due to a decline of cellular Ca2+ concentration and decreased Ca2+ sensitivity of LC20 phosphorylation, named Ca2+ desensitization. Here, we determined the mechanisms underlying the temporal Ca2+ desensitization of LC20 phosphorylation in phasic smooth muscles using permeabilized strips of the mouse ileum and urina

APA, Harvard, Vancouver, ISO, and other styles

50

Scaringi, Riccardo, Michele Nannelli, Alessio Franchina, et al. "Full Zirconia Implant-Born Prosthetic Rehabilitation with CAD/CAM Technology after Accurate Digital Planning. A Case Report." International Journal of Environmental Research and Public Health 18, no. 15 (2021): 7998. http://dx.doi.org/10.3390/ijerph18157998.

Full text

Abstract:

CAD/CAM technology can enhance the dentistry application of ceramic materials that meet the more relevant biocompatibility and aesthetics demands. In implant-borne prosthesis rehabilitation, yttria-stabilized zirconia appeared to be a valid alternative to metal-alloys and titanium, with comparable mechanical properties and even better interaction with bone and soft tissues. The improvement of monolithic CAD/CAM manufacturing allows for a reliable, predictable, and rapid workflow that can correspond to a holistic treatment philosophy associated with zirconia fixtures. This reported clinical cas

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!