Academic literature on the topic 'Cancer patients as artists'

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Journal articles on the topic "Cancer patients as artists"

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Weeseman, Yvonne, Michael Scherer-Rath, Nirav Christophe, Henny Dörr, Zarah M. Bood, Mirjam A. G. Sprangers, Esther Helmich, and Hanneke W. M. van Laarhoven. "Co-creative art processes with patients: A theoretical framework and qualitative study among artists." PLOS ONE 17, no. 4 (April 7, 2022): e0266401. http://dx.doi.org/10.1371/journal.pone.0266401.

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A cancer diagnosis may be experienced as a contingent life event. Co-creation—in which artists together with patients create a work of art reflecting on aspects of the patients’ life story—may be used to support patients to integrate such a contingent life event into their life story. We conducted a qualitative study in which we interviewed 10 professional artists to explore if co-creative art processes could facilitate integration of experiences of contingency in patients. Template analyses were performed in AtlasTi. We identified co-creation as a specific form of support to the process of integration of experiences of contingency. In the formation of a new life narrative, patients transcend the boundaries of their previous life narrative by changing their perspective. Self-transcendence forms a pivotal point in co-creation, which may be helpful for patients to integrate experiences of contingency into their life narratives.
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Mohammed, S., Z. Bagudu, and A. Aliyu. "Kick Out Cancer Campaign." Journal of Global Oncology 4, Supplement 2 (October 1, 2018): 185s. http://dx.doi.org/10.1200/jgo.18.62900.

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Amount raised: N17,307,000 Background and context: The power of games for social change is well documented. Football, the world's most popular game is a common passion shared by most Nigerians across all divides. It defies all barriers and unites people globally. Beyond the potential for cancer awareness creation using football games, it can also be used to raise funds for cancer course. Aim: The aim was to increase cancer awareness via community participation and involvement as well as raise funds for cancer patients. To encourage the population to engage in healthy lifestyles and physical activities in lowering the risks of cancer. Strategy/Tactics: We partnered with the League Management Company- Nigeria Professional Football League and the Nigerian Football Federation (NFF) for technical support to portray a tone of professionalism in our novelty football tournament. We worked a long side with expert active, retired, Nigerian and international professional footballers as well as artists to bring out in mass fans and the community at large toward achieving our goals. Radio and television jingles were made to ensure maximum reach out to the masses. Social media hype was done where some selected players called on to their fans to get involved. An awareness 5-km walk was organized where kits (T-shirts, face caps, wrist bands) were sold in addition to the tickets for the tournament. Footballers signed on various T-shirts which were auctioned during the tournament as well as arts and jewelry. Program process: Active and retired footballers were engaged as well as prominent local artist to bring out crowd in mass crowd that benefitted in this campaign. All transactions made were through the foundation's account for credibility. Costs and returns: Costs: media and logistics - N1,000,000, walk kits and jerseys - N1,500,000, food and refreshments - N1,300,000, security - N200,000, event planners - N300,000, kids corner - N500,000. Total N4,800,000 Returns: tickets and coupon sales - N1,057,000, walk kits sold - N 3,050,000, players registration - N200,000, teams registration - N4,000,000, stands sold - N250,000, auctioned art - 1,000,000, auctioned jerseys - N1,500,000, auctioned jewelry - 250,000, donations received - N10,800,000. Total N22,107,000 What was learned: A lot can be achieved collectively as a community in reducing the burden of costs in the treatment of cancer.
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Page, Margaretta S., Mary Lovely, Abigail Levinson Marks, Amanda K. LaMarre, Susan M. Chang, Jennifer Clarke, Judy Patt, and Emelia Barani. "Family Camp: A multi-disciplinary intervention for brain tumor patients and families." Journal of Clinical Oncology 34, no. 26_suppl (October 9, 2016): 240. http://dx.doi.org/10.1200/jco.2016.34.26_suppl.240.

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240 Background: The diagnosis of a brain tumor is a catastrophic life changing event that impacts the entire family. Patients and caregivers experience dramatic role changes, concern for their children, financial stress, and isolation. For many, the situation is overwhelming. A novel intervention to address these needs is “Family Camp”. Our vision for camp was to provide respite to the entire family, decrease caregiver stress, improve family connections and promote a sense of understanding and connection with the community at large. Methods: In a unique partnership with the widow of a former patient, the members of the UCSF Neuro-Oncology Division created and offered a weekend camp for brain tumor patients with children. Team members included MDs, RNs, social workers, psychologists, artists, body workers, “camp counselors” and community volunteers. In addition to respite, camp was structured through art, songs, projects and games to deliver opportunities for understanding and community building, including understanding the disease and its impact on the family. Therapeutic interventions included couples activities, counseling, parenting strategies, and providing a sense of connection to others dealing with brain tumors, the health care team, and camp volunteers. Anxiety, stress, depression, coping and values based living were measured pre and post camp using DASS21, CES-D, Brief Cope, Values Based Living instruments, and survey questions. Results: 11 families attended camp for 3 days in 2014. Improvement was noted in post camp testing of depression, anxiety and stress versus pre-camp. Survey questions showed the most common and important outcome to be connection, specifically that patients, caregivers, and children made connections with similar others. Families reported being able to relax and felt taken care of. They liked the opportunity for undistracted family time, getting to know their health providers outside of the office, and couples benefited from family counseling. Conclusions: Capitalizing on the unique skills of a multi-disciplinary team, one that includes the patient’s health care team, can lead to the delivery of a novel intervention that improves the illness experience of brain tumor patients and families.
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Mohamed, A. "Empowering Cancer Survivors to Become Mentors, and Leaders Through Various Workshops and Programs." Journal of Global Oncology 4, Supplement 2 (October 1, 2018): 174s. http://dx.doi.org/10.1200/jgo.18.15800.

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Background and context: Friends of Cancer Patients UAE conducts various moral support programs for cancer patients, one of which is the “Color My World” program, which focuses on provide moral support to predominantly men and women, who have undergone, or are currently undergoing treatment of cancer. Aim: The aim is to empower cancer survivors to become leaders and mentors to other ladies/men currently undergoing treatment, and to establish a survivor led support program, as a result of these various programs and workshops. Strategy/Tactics: We believe that to for such a program to be a success, you need to understand your target group, their interests, as well as their backgrounds. A needs assessment needs to be conducted prior to the selection of workshops, whether through direct interviews with the patients, or internally by examining the different support programs available in the country, and what is available/not available. Program/Policy process: There are numerous workshops that take place throughout the year, and they are divided as follows: - There are workshops that focus on healthy living, and the importance of a healthy diet, which involves numerous cooking workshops, and educational sessions. - There are workshops that focus on skin care and make-up, where the ladies are taught how to take care of themselves by certified stylists and makeup artists. - Those who are interested in crochet and handicrafts, have the chance to take part in group workshops, or in focused 1 to 1 sessions. Outcomes: There are a number of positive outcomes that came about from our attempts to empower cancer survivors, the ones we believe are worth of being highlighted are: - A group of survivors are now leading, and running a cancer support program, that visits hospitals within the UAE, to visit those currently undergoing treatment, to provide support, and assist those still undergoing treatment in any way possible. - Many of the ladies, who attended previous workshops, will now start to lead similar workshops during hospital visits to children and women with cancer. What was learned: Cancer survivors must be the driving force in providing support to other cancer patients, and the existing model of the support groups can be linked with the educational workshops, to not only provide moral support, but also social support to the cancer patient.
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Oliveira, Sherida Karanini Paz de, and Francisca Elisangela Teixeira Lima. "Brazilian scientific production about nursing consultation applied to cancer patients." Revista de Enfermagem UFPE on line 4, no. 2 (March 31, 2010): 850. http://dx.doi.org/10.5205/reuol.757-7138-1-le.0402201050.

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ABSTRACT Objectives: to identify the scientific production on the nursing consultation in oncology and analyze the methodologies used in these papers. Method: this is about a bibliographic study was conducted from May to June 2009, in articles published in the twenty-first century (2001-2009), by an electronic search in the database Latin American Literature in Health Sciences (LILACS), Scientific Electronic Library Online (Scielo) e Medical Literature On-Line (Medline). Met the inclusion criteria of six articles, which were analyzed and discussed according to the literature. Results: the methodological aspects prevailing were: four are research paper, one a report of experience and one convergent-care and all articles are qualitative. Concerning the characteristics of the populations studied, five investigated adult patients and one studied nurses. Regarding the subject of studies, were found three articles that addressed the implementation of nursing consultation, and the other evaluated each nursing consultation itself, its meaning for the patient and the significance for nurses. Conclusion: noticed that the number of publications related to the thematic nursing ambulatory consultation in the oncology practice in Brazil is very low. Descriptors: nursing; oncology; journal article; nursing care; technology; health education; radiotherapy. RESUMOObjetivos: identificar a produção cientifica sobre a consulta de enfermagem em oncologia e analisar as metodologias empregadas nesses artigos científicos. Método: trata-se de um estudo bibliográfico, cujo levantamento de dados foi realizado no período de maio a junho de 2009, nos artigos publicados no século XXI (2001-2009), por busca eletrônica no banco de dados Literatura Latino-Americana em Ciências de Saúde (LILACS), Scientific Electronic Library Online (Scielo) e Medical Literature On-Line (Medline). Atenderam aos critérios de inclusão 6 artigos, os quais foram analisados e discutidos conforme a literatura. Resultados: quanto aos aspectos metodológicos, quatro são trabalhos de levantamento, um relato de experiência e um convergente-assistencial e todos são qualitativos. Com relação às populações estudadas, cinco investigaram os pacientes e um os enfermeiros. Em relação à temática dos estudos, foram encontrados três artigos que abordaram a implantação da consulta de enfermagem, e os demais cada um avaliou a consulta de enfermagem propriamente dita, seu significado para o paciente e o significado para o enfermeiro. Conclusão: percebeu-se que a quantidade de publicações que abordam a consulta ambulatorial de enfermagem na prática oncológica, no Brasil, é muito reduzida. Descritores: enfermagem; oncologia; artigo de revista, cuidados de enfermagem; tecnologia; educação em saúde; radioterapia.RESUMEN Objetivos: identificar la producción científica sobre la consulta de enfermería en oncología y analizar las metodologías empleadas en estos artículos científicos. Método: el levantamiento bibliográfico fue realizado en el período de mayo a junio de 2009, en artículos publicados en el vigésimo siglo primero (2001-2009), por busca electrónica, pela BIREME, en el banco de datos Literatura Latino-Americana en Ciencias de Salud (LILACS), Scientific Electronic Library Online (Scielo) e Medical Literature On-Line (Medline). Cumplieron con los criterios de inclusión, de 6 artículos, que fueron analizados y discutidos de acuerdo a la literatura. Resultados: sobre los aspectos metodológicos, cuatro son trabajo de investigación, un relato de experiencia y una atención convergente y todos los artículos son de carácter cualitativo. Con relación a las características de las poblaciones estudiadas, cinco investigaron los pacientes y uno estudió los enfermeros. En relación a la temática de los estudios, fueron encontrados tres artículos que abordaron la implantación da consulta de enfermería, y los otros evaluados la consulta de enfermería en sí, su significado para el paciente y para el enfermero. Conclusión: se observó que la cantidad de publicaciones que abordan la temática consulta ambulatoria de enfermería en la práctica oncológica, en Brasil, es muy reducida. Descriptores: enfermería; oncología; artículo de revista; atención de enfermería; tecnología; educación en salud, radioterapia.
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Park, Se Hoon, Su Jin Lee, Seung Tae Kim, Jeeyun Lee, Joon Oh Park, Young Suk Park, Ho Yeong Lim, and Won Ki Kang. "Multicenter phase III trial of adjuvant chemoradiotherapy in stomach tumors 2 (ARTIST 2)." Journal of Clinical Oncology 33, no. 3_suppl (January 20, 2015): TPS228. http://dx.doi.org/10.1200/jco.2015.33.3_suppl.tps228.

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TPS228 Background: Treatment of gastric cancer (GC) has some notable differences between Asia and Western countries including the extent of surgery and the type of adjuvant therapy. In ARTIST trial comparing adjuvant chemotherapy involving capecitabine plus cisplatin with chemoradiotherapy, we reported comparable disease-free survival (DFS) in Korean patients with D2-resected GC. In subset analyses, patients with node-positive disease and intestinal type GC may have benefit with the addition of radiotherapy to adjuvant chemotherapy. Methods: ARTIST 2 (ClinicalTrials.gov, NCT0176146) is a 3-arm, multi-center, open-label phase III trial comparing adjuvant chemotherapy involving S-1 (40 mg/m2 bid 4-weeks-on/2-weeks-off) for one year (arm A) with S-1 plus oxaliplatin (SOX, S-1 40 mg/m2 bid 2-weeks-on/1-week-off plus oxaliplatin 130 mg/m2 iv on day 1) for 8 cycles (arm B) and chemoradiotherapy (arm C). Arm C patients receive SOX for 2 cycles, then concurrent chemoradiotherapy 45 Gy with S-1 40 mg bid daily, followed by additional SOX for 4 more cycles. Patients are randomized 1:1:1 with 3 strata: stage (II or III), type of surgery (subtotal or total gastrectomy) and Lauren classification (diffuse or intestinal type). Eligibility criteria include gastric or gastro-esophageal junction adenocarcinoma, D2 or higher surgery with no residual disease, pathologic stages 2 or 3, lymph node positive disease. Primary endpoint is DFS, and secondary endpoints include overall survival, safety, QOL and molecular biomarkers. To test if experimental arms (arm B or C) lower the hazard of recurrence by 50% (i.e., HR 1.5) compared to arm A, we need 900 patients (300 per arm) with 90% of overall statistical power. First patient entered onto the study in Feb 2013. As of Aug 2014, a total of 118 (13% of target) patients were recruited by 8 Korean tertiary centers. Clinical trial information: NCT0176146.
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Miceli, Rosalba, Jiyeong An, Maria Di Bartolomeo, Federica Morano, Seung Tae Kim, Se Hoon Park, Min Gew Choi, et al. "Prognostic Impact of Microsatellite Instability in Asian Gastric Cancer Patients Enrolled in the ARTIST Trial." Oncology 97, no. 1 (2019): 38–43. http://dx.doi.org/10.1159/000499628.

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Silva, Maria Enoia Dantas da Costa e., Liana Dantas da Costa e. Silva, Amanda Lúcia Barreto Dantas, Daniela Oliveira Rufino de Araújo, Isabela Santana Duarte, and Jainara Francisca Matias de Sousa. "Nursing care to cancer patients in the hospital / Assistência de enfermagem ao paciente oncológico no hospital." Revista de Enfermagem da UFPI 2, no. 5 (March 26, 2014): 69. http://dx.doi.org/10.26694/reufpi.v2i5.1359.

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Objetivo: realizar o levantamento e análise das publicações e suas contribuições sobre a assistência de enfermagem ao paciente oncológico no hospital. Metodologia: Trata-se de uma revisão integrativa a partir da seleção de 20 artigos em periódicos de enfermagem no período de 2004 a 2012. Resultados: Da análise dos artigos surgiram duas categorias, a primeira formada pelos núcleos semânticos de 14 artigos que tratavam da essência desta assistência que deve significar desvelo, solicitude, diligência, zelo, atenção. A segunda, constituída a partir de 6 artigos que tratavam da internação como um momento doloroso e de sofrimento ao paciente e família. A produção evidenciou a necessidade de ultrapassagem da dimensão biológica do cuidar para a construção, com os pacientes, de estratégias de sobrevivência com qualidade. Conclusão: O enfermeiro desta área deve assistir de forma humanizada, acolhedora e participativa, bem como na prevenção de futuras complicações. As publicações trazer contribuições efetivas para os enfermeiros.
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Lee, Jeeyun, Do Hoon Lim, Sung Kim, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, et al. "Phase III Trial Comparing Capecitabine Plus Cisplatin Versus Capecitabine Plus Cisplatin With Concurrent Capecitabine Radiotherapy in Completely Resected Gastric Cancer With D2 Lymph Node Dissection: The ARTIST Trial." Journal of Clinical Oncology 30, no. 3 (January 20, 2012): 268–73. http://dx.doi.org/10.1200/jco.2011.39.1953.

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Purpose The ARTIST (Adjuvant Chemoradiation Therapy in Stomach Cancer) trial was the first study to our knowledge to investigate the role of postoperative chemoradiotherapy therapy in patients with curatively resected gastric cancer with D2 lymph node dissection. This trial was designed to compare postoperative treatment with capecitabine plus cisplatin (XP) versus XP plus radiotherapy with capecitabine (XP/XRT/XP). Patients and Methods The XP arm received six cycles of XP (capecitabine 2,000 mg/m2 per day on days 1 to 14 and cisplatin 60 mg/m2 on day 1, repeated every 3 weeks) chemotherapy. The XP/XRT/XP arm received two cycles of XP followed by 45-Gy XRT (capecitabine 1,650 mg/m2 per day for 5 weeks) and two cycles of XP. Results Of 458 patients, 228 were randomly assigned to the XP arm and 230 to the XP/XRT/XP arm. Treatment was completed as planned by 75.4% of patients (172 of 228) in the XP arm and 81.7% (188 of 230) in the XP/XRT/XP arm. Overall, the addition of XRT to XP chemotherapy did not significantly prolong disease-free survival (DFS; P = .0862). However, in the subgroup of patients with pathologic lymph node metastasis at the time of surgery (n = 396), patients randomly assigned to the XP/XRT/XP arm experienced superior DFS when compared with those who received XP alone (P = .0365), and the statistical significance was retained at multivariate analysis (estimated hazard ratio, 0.6865; 95% CI, 0.4735 to 0.9952; P = .0471). Conclusion The addition of XRT to XP chemotherapy did not significantly reduce recurrence after curative resection and D2 lymph node dissection in gastric cancer. A subsequent trial (ARTIST-II) in patients with lymph node–positive gastric cancer is planned.
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Vangolu, Yeliz Biber. "Exploding the Cancer Myths: Brian Lobel’s Narrative Performance Ball." European Journal of Language and Literature 8, no. 1 (May 19, 2017): 147. http://dx.doi.org/10.26417/ejls.v8i1.p147-152.

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In his personal account of cancer, Ball (2003), the performance artist, Brian Lobel, intently refuses to succumb to the myths about the illness, challenging the cancer narratives that have traditionally been based on a discourse of heroism or martyrdom. While his performance is, at times, sensational with a keen focus on sexuality and a determination to produce humour out of a grave matter, they invite criticism for the way cancer has been perceived and presented as a medical condition and for the social stigma attached to the disease. This paper addresses the numerous ways in which Lobel challenges the assumptions, expectations and taboos regarding cancer, cancer patients and survivors by examining his strategies in the light of cultural studies on cancer and humour theories.
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Dissertations / Theses on the topic "Cancer patients as artists"

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Engler, Jennifer [Verfasser]. "Cancer Care and Cancer Patients’ Experiences with Cancer / Jennifer Engler." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2019. http://d-nb.info/1180994191/34.

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OLSSON, MILLA, and CAROLINE ROSELL. "Telemedicine for Lung Cancer Patients." Thesis, KTH, Skolan för datavetenskap och kommunikation (CSC), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-136951.

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Den svenska sjukvården står idag för ett antal utmaningar om den skall fortsatt kunna erbjuda god service som vårdgivare och vara attraktiv som arbetsgivare. Bland annat diskuteras frågor som förvärrad platsbrist, läkarbrist samt avstånd till specialistsjukvård. På Karolinska Universitetssjukhuset i Solna ligger Radiumhemmet och där behandlas bland annat lungcancerpatienter. Där diskuteras huruvida telemedicin kan vara en möjlig väg för att lösa ovanstående problem. Denna uppsats utreder på vilket sätt telemedicin kan användas på Radiumhemmet för lungcancerpatienter. För att kunna utreda en telemedicinsk lösnings möjligheter på Radiumhemmet genomfördes intervjuer och fokusgrupper med personalen. Externa experter från sjukvården och industri intervjuades och ett besök gjordes på barnsjukhuset Childrens Healthcare of Atlanta, USA, där man har kommit långt i användningen av telemedicin. Det finns delar av verksamheten på Radiumhemmet där telemedicin skulle kunna bidra till att skapa möjligheter till en tätare kontakt mellan patient och vårdpersonal. Detta i syfte att lugna oroliga patienter och hjälpa till med lättare symptombedömningar och på så sätt minska väntetiderna. Genom de undersökningar som utfördes upptäcktes dock även svagheter i en telemedicinsk lösning avsedd för lungcancerpatienter. Patientgruppen ofta är äldre med liten erfarenhet av datorer och sjukdomen är allvarlig. Det krävs personlig kontakt och fysiska undersökningar, men i vilken utsträckning är individuellt. Telemedicin kanske inte kan ses som en absolut lösning för de problem som råder i sjukvården idag när det kommer till lungcancerpatienter, men väl som ett komplement. Om lungcancerpatienter är den optimala målgruppen är ifrågasättbart men att telemedicin kan underlätta i den svenska sjukvården står klart.
Nowadays the health care system in Sweden is faced with several challenges like shortage of space, physicians and long distances to specialized health care. A possible solution for this being discussed at the lung cancer department of Karolinska University 2 Hospital is the use of telemedicine. If implemented it would be part of the followup treatment. The objective of our research is to find out if this technology can help improve the health care. In order to investigate the opportunity for a telemedicine solution, we collected qualitative data from multiple different sources. This included two doctors specialized in lung cancer, and a focus group with nurses from Radiumhemmet. We also conducted interviews with relevant individuals outside the hospital including Nirav Desai who is the Founder and CEO of Hands On Telehealth; furthermore, we visited the Children’s Healthcare of Atlanta based in Atlanta, Georgia where telemedicine is used on a daily basis. Thanks to the carried out research, we have discovered that telemedicine could be used in certain scenarios and contribute towards a more frequent contact between the patient and the medical professionals. Thus, this new technique could help nurses execute lighter symptoms assessment remotely and reduce waiting times. We also discovered some inconveniences in a telemedicine solution designed for lung cancer patients. We personally do not think they are the best target group for such a solution since the patients are mostly the elderly with little computer experience. Also the disease is severe and requires physical examinations where the telemedicine existing today would not improve the care giving. To all intents and purposes, telemedicine might not be the only and ultimate solution for the problems identified within healthcare for lung cancer patients at Radiumhemmet, but it can work well as a supplement. 3
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Fredrix, Elisabeth Wilhelmina Hubertina Maria. "Energy metabolism in cancer patients." Maastricht : Maastricht : Datawyse ; University Library, Maastricht University [Host], 1990. http://arno.unimaas.nl/show.cgi?fid=5567.

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Kaur, Jasmine. "Preventative Vaccine for Cancer patients." Thesis, Griffith University, 2022. http://hdl.handle.net/10072/413312.

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Cancer is an age-old disease and a leading cause of mortality worldwide. It starts with the development of abnormal cells that multiply to form tumours and may lead to metastasis causing damage to healthy tissues and organs of the body. Lung cancer is the most common type of cancer with significant morbidity and mortality globally and is of major concern for the society. Decades of research and innovation in the treatment of cancer led to the development of certain conventional therapies such as surgery, radiotherapy, and chemotherapy that are being effectively used. However, these traditional therapies have a disadvantage of destroying healthy cells and tissues in its close proximity, leading to other severe diseases and side effects. Therefore, a much-advanced approach to treat cancer without causing severe side effects became an important area of research. Improvements in the field of anti-cancer therapies led to a strategy to combine traditional treatment approaches to destroy cancer cells. Additionally, treatments such as targeted therapies, hormone therapy, and precision medicine came into existence. Alternatively, the immune system was analysed to determine an effective approach that could control proliferation of cancer cells and cause limited or no damage to other cells. This area of cancer therapeutics, known as immunotherapy, targets the immune system to enhance its ability of recognizing invasive neoplasms. Our immune system in response to an infection immediately activates immune cells, creating a protective immunity for decades. Unfortunately, this immune response often fails when fighting against cancer and is unable to entirely eliminate tumour cells or develop effective immunity. Cancer vaccines, a branch of immunotherapy that has potential therapeutic benefits can build immunity and ultimately lead to prevention from future illness. These have been employed to treat the disease using tumour associated antigens and various adjuvants or immune stimulators and only a few have been in clinical trials. The potential of such cancer vaccines can be exploited to further develop treatment strategies to prevent tumour occurrence and provide long-lasting immunity. This study was designed to primarily explore the potential of a novel immune stimulator, RNA:DNA hybrid and an established TLR9 agonist, CpG 7909. Furthermore, these agonists were used to develop a preventative cancer vaccine in association with a tumour associated carbohydrate antigen, Globo-H to determine whether the novel formulation could improve immune response and trigger antigen presentation in vitro and in vivo. In an in vivo setting, these were also investigated against lung cancer to determine their potential in preventing tumour occurrence. Within this study RAW 264.7 mouse macrophages were initially exposed to varying concentrations of CpG 7909, RNA:DNA hybrid, and Globo-H to determine the optimum dose concentration for the activation of antigen presenting cells by measuring the level of TNF-α secreted in cell culture supernatant. Following dose optimization, the individual agents were combined in a vaccine formulation, sharing the same antigen, where two cell lines, mouse RAW 264.7 macrophages and human monocytic cell line, THP-1 that was differentiated into macrophages and dendritic cells were exposed to the vaccines. TNF-α, IL-12 and IL-6 cytokine response was analysed as measured by ELISA and real-time PCR that were determined to be partially significant in response to the vaccines. The degree of immune response demonstrated by RNA:DNA hybrid-based vaccine (HG-Vax) confirmed that HG-Vax is more effective than CpG 7909-based vaccine (CG-Vax). This response was further analysed in an in vivo model where C57/BL mice were exposed to immune stimulators and vaccines separately for 14- and 28-days before end point termination. Serum was analysed for IL-12 and TNF-α to determine the level of inflammatory response. Even though statistical significance was not achieved in vivo, contrasting observations compared to the in vitro model were exhibited. Secretion of IL-12 in animals confirmed the induction of an anti-tumour immune response. Interestingly, cytokines induced by single dose CG-Vax persisted for a longer period of time in blood in comparison to HG-Vax. However, opposite was true with the booster immunization. In animal model of lung cancer, statistical significance validates that booster immunization with HG-Vax triggers an immune response and upregulates MHC II expression. Unfortunately, CG-Vax did not induce a significant immune response and failed to induce MHC II expression in an in vivo model of lung cancer. Although these findings present RNA:DNA hybrid to be a novel immune stimulator that may have the potential to be used in future cancer vaccinations, further investigation on its immunological potential and mechanism of action remains of need.
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Pharmacy & Med Sci
Griffith Health
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McMenamin, Úna. "Pharmacological exposures, cancer treatments and disease progression among cancer patients." Thesis, Queen's University Belfast, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.679267.

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The evidence base for the effect of common pharmacological exposures among patients diagnosed with cancer is sparse. Routinely collected health data however, can facilitate the conduct of pharmacoepidemiological research into cancer care and outcomes. This PhD study comprised (i) a systematic review of angiotensin-converting enzyme inhibitor (ACEI) and angiotensin receptor blocker (ARB) use and cancer progression and survival; (ii) a systematic review and meta-analysis of non-steroidal anti-inflammatory drug (NSAID) use and colorectal cancer outcomes; (iii) a nested-case control study of ACEI and ARB use and risk of breast cancer mortality; (iv) a nested-case control study of ACEI and ARB use and risk of prostate cancer mortality and; (v) an overview of cancer treatments received among women, recently diagnosed with breast cancer in Northern Ireland. Individual studies identified within the first systematic review showed inconsistencies with respect to the association between ACEls/ARBs and cancer outcomes and following on from this, findings from two large population-based studies indicated little evidence of a beneficial association between ACEI or ARB use and breast and prostate cancer mortality outcomes, respectively, although a possible protective association was noted for ACEls and risk of prostate cancer mortality. Similarly, there was limited evidence to suggest an association between NSAID use and clinical outcomes from colorectal cancer, based on findings from the second systematic review and meta-analysis. Using data sources from within the Northern Ireland Cancer Registry, a retrospective population-based dataset of breast cancer patients, recently diagnosed in Northern Ireland was constructed. Cancer treatments were deemed appropriate and particular attention was given to adjuvant systemic therapies (including chemotherapy and hormone therapy). This dataset will enable future data linkage with dispensed medication records. Considering the frequency with which ACEls, ARBs, as well as NSAIDs are prescribed, further research into cancer outcomes with respect to these agents is warranted.
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Wolfman, Jessica Heather Kloss Jacqueline D. "Cancer specific stress and insomnia severity among breast cancer patients /." Philadelphia, Pa. : Drexel University, 2009. http://hdl.handle.net/1860/3024.

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Radu, Calin. "Optimising Radiotherapy in Rectal Cancer Patients." Doctoral thesis, Uppsala universitet, Enheten för onkologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-172531.

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Rectal cancer is the eight most common cancer diagnosis in Sweden in both men and women, with almost 2000 new cases per year. Radiotherapy, which is an important treatment modality for rectal cancer, has evolved during the past decades. Diagnostic tools have also improved, allowing better staging and offering information used to make well-founded decisions in multidisciplinary team conferences. In a retrospective study (n=46) with locally advanced rectal cancer (LARC) patients, unfit for chemoradiotherapy, patients were treated with short-course radiotherapy. Delayed surgery was done when possible. Radical surgery was possible in 89% of the patients who underwent surgery (80%). Grade IV diarrhoea affected three elderly patients. Target radiation volume should be reduced in elderly or metastatic patients. In a prospective study (n=68) with LARC patients, magnetic resonance imaging (MRI) and 2-18F-fluoro-2-D-deoxyglucose (FDG) positron emission tomography (PET) were used to determine if FDG-PET could provide extra treatment information. Information from FDG-PET changed the stage of 10 patients. Delineation with FDG-PET generally resulted in smaller target volumes than MRI only. Seven of the most advanced LARC patients in the above cohort were used for a methodological study to determine if dose escalation to peripheral, non-resectable regions was feasible. Simultaneous integrated boost plans with photons and protons were evaluated. While toxicity was acceptable in five patients with both protons and photons, two patients with very large tumours had unacceptable risk for intestinal toxicity regardless of modality. In the interim analysis of the Stockholm III Trial (n=303, studying radiotherapy-fractionation and timing of surgery in relation to radiotherapy) compliance was acceptable and severe acute toxicity was infrequent, irrespective of fractionation. Short-course radiotherapy with immediate surgery tended to give more postoperative complications, but only if surgery was delayed more than 10 days after the start of radiotherapy. Quality-of-life in the Stockholm III Trial was studied before, during and shortly after treatment using the EORTC QLQ-C30 and CR38 questionnaires. Surgery accounted for more adverse effects than radiotherapy in all groups. Postoperatively, the poorest quality-of-life was seen in patients given short-course radiotherapy followed by immediate surgery. No postoperative differences were seen between the two groups with delayed surgery.
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Nna, Emmanuel Okechukwu. "Molecular profiling of prostate cancer patients." Thesis, Cranfield University, 2009. http://dspace.lib.cranfield.ac.uk/handle/1826/4527.

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In the UK, more than 30 000 men are diagnosed annually with prostate cancer (PCa) and about 10 000 men die from it each year. Although several molecular markers have been associated with prostate cancer development and/ or progression, only few of them are used in diagnostic pathology. The current standard tests include serum PSA test, digital rectal examination and histology of prostate biopsy. Recently the PCA-3 molecular test was approved in the European Union, and it is now used in many laboratories. But these tests are not sufficient to molecularly characterise the behaviour of prostate cancer in many patients. Through extensive literature review, a panel of sixteen molecular markers were selected for further evaluation in prostate cancer cases. They included KLK2, KLK3, MCM2, MCM5, TP53, Bcl-2, CD44, CDH1, AURKA, AURKB, and AURKC; ESR , ESR , AR, FASN, TMPRSS2: ERG, and TMPRSS2:ETV1. The aim was to examine the link between development/progression of prostate cancer and the production of diagnostic/prognostic biomarkers. An in vitro model consisting of PC-3 and PNTIA, MDA PCa 2b prostate cell lines were used to investigate the influence of steroid hormones on these biomarkers using molecular and proteomic techniques. All the three cell lines expressed AR, ESR , ESR and PSA at mRNA and protein levels. The AR expressed in PC-3 and MDA PCA 2b cells was 60 kDa while the PNT1A expressed a 90 kDa AR protein. The ESR was over-expressed in the MDA PCA 2b cells, and was also significantly up-regulated by 17 oestradiol treatment. At a concentration of 4.92 and 33.96μM 17 oestradiol inhibited the growth of 10 to 50% of PNT1A cell line and increased the doubling time three folds. Although the PC-3 cells expressed AR, it was still androgen insensitive and could not produce PSA in culture supernatants. AR and PSA were up-regulated in PNT1A cells in response to testosterone and dihydrotesterone treatment but were reduced in response to 17 oestradiol and Hydrocortisone treatment. All the molecular markers except the TMPRSS2: ERG and TMPRSS2:ETV1 were expressed in the cell lines. The MCM2 and MCM5 were not differentially expressed in response to hormonal treatment. However, the Aurora kinases A, B and C were up-regulated in response to steroid modulation. The KLK2 was only up-regulated by the androgens. Three candidate control genes: ABL1, GUS and G6PD were also evaluated in the cell lines and clinical samples; the ABL1 gene emerged as the most stably expressed house keeping gene and was subsequently used in the normalization of real time PCR assays (RQ-PCR). Analysis of the sixteen biomarkers in prostate tissues and exfoliated urine cells of benign, prostate cancer and non-involved cases (n = 228) showed that seven of the molecular markers were significantly strongly associated with prostate cancer progression (P<0.05). The Aurora kinases A and B were consistently significantly over-expressed in prostate cancer cases. The CD44 was also over-expressed in prostate cancer, and was associated with Gleason score. The TMPRSS2 fusion genes were detected in 15.6% of the prostate cancer cases. The TP53 was also over-expressed in prostate cancer, and significantly associated with tumour grade. The ESR was over-expressed in prostate cancer, and was significantly associated with high tumour grade. This implied a proliferative role for the ESR in prostate cancer progression, because the ESR was not differentially expressed among the sample groups. Concomitantly, the AR was also over-expressed in same pattern with ESR . The combination of these biomarkers: AR, ESR , CD44, TP53, TMPRSS2 fusion genes, AURKA and AURKB could molecularly characterise most prostate cancers. Therefore 2 sets of pentaplex RQ-PCR assays including ABL1 for normalization would provide a cost-effective, flexibly high throughput assay for molecular grading of tissue sections in diagnostic pathology. In addition to the gene expression studies, the genetic variation in KLK2 gene was further investigated by direct DNA sequencing, pyrosequencing and TaqMan allelic discrimination assay. Two SNPs in the gene were found significantly associated with prostate diseases. The T/T allele of rs198977 predicted the presence of prostate cancer at biopsy and was associated with high tumour grade. The A/A variant of rs2664155 was also significantly associated with the presence of benign nodular hyperplasia. The combination of gene expression and genetic variation using real time PCR applications would provide an accurate, reproducible and cheap method for molecular profiling of prostate cancer patients. An exploratory study of organic volatiles in urine of one prostate cancer patient and eight BPH patients using thermal desorption GC-MS showed that Ethanethiol, Dimethyl sulfide, Propyn-1-ol acetate, Nitro-2-propanone, pentane, Hydrazine and Nitrous oxide were differentially over-expressed in the prostate cancer patient compared to the benign cases. Further studies would be required to rule out possible contamination and drug metabolites.
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Viganó, Antonio Angelo Luciano. "Survival predictors in advanced cancer patients." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0007/MQ28996.pdf.

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Persson, Christina. "Improved Nutritional Support in Cancer Patients." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5218-3/.

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Books on the topic "Cancer patients as artists"

1

Meynell, Katharine. It's inside. New York: Marion Boyars Publishers, 2005.

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Davidson, Laura. Voices from my cancer year, 2004. [Boston: Laura Davidson, 2005.

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Pope, Robert. Illness & healing: Images of cancer. Hantsport, N.S: Lancelot Press, 1991.

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Pope, Robert. Illness & healing: Images of cancer. Hantsport, N.S: Lancelot Press, 1991.

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Cornett, Laura. Ordinary holiness. Montreal, Quebec]: Sara Cornett Photography, 2010.

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M, Love Susan, and Yood James, eds. Hollis Sigler's breast cancer journal. New York: Hudson Hills Press, 1999.

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Treading the maze: An artist's journey through breast cancer. San Francisco: Chronicle Books, 1997.

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Stokke, Regine. Regines bok: En ung jentes siste ord. Oslo: Gyldendal, 2010.

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Garrity, Jack. A passion to paint: The colorful world of Pacita Abad. Singapore: "Fundacíon Pacita", The Pacita Abad Foundation, 2005.

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Sobol, Karen Lee. Twelve weeks: An artist's story of cancer, healing, and hope. [Boston]: [Karen Lee Sobol], 2011.

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Book chapters on the topic "Cancer patients as artists"

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Fan, Timothy M. "Cancer Patients." In Veterinary Anesthesia and Analgesia, 993–1003. Chichester, UK: John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781119421375.ch55.

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Deixonne, B. "Treated Patients." In Exocrine Pancreatic Cancer, 201–8. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71178-7_11.

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De Conno, F., and K. Foley. "Elderly patients." In Cancer Pain Relief, 39. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0099-1_19.

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Timmermann, Carsten, and Elizabeth Toon. "Introduction." In Cancer Patients, Cancer Pathways, 1–9. London: Palgrave Macmillan UK, 2012. http://dx.doi.org/10.1057/9781137272089_1.

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Zuiderent-Jerak, Teun, Roland Bal, and Marc Berg. "Patients and their Problems: Situated Alliances of Patient-Centred Care and Pathway Development." In Cancer Patients, Cancer Pathways, 204–29. London: Palgrave Macmillan UK, 2012. http://dx.doi.org/10.1057/9781137272089_10.

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Pickstone, John. "Radicalism, Neoliberalism and Biographical Medicine: Constructions of English Patients and Patient Histories Around 1980 and Now." In Cancer Patients, Cancer Pathways, 230–55. London: Palgrave Macmillan UK, 2012. http://dx.doi.org/10.1057/9781137272089_11.

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Baines, Joanna. "Three Stories: Generations of Breast Cancer." In Cancer Patients, Cancer Pathways, 13–35. London: Palgrave Macmillan UK, 2012. http://dx.doi.org/10.1057/9781137272089_2.

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Timmermann, Carsten. "Running Out of Options: Surgery, Hope and Progress in the Management of Lung Cancer, 1950s to 1990s." In Cancer Patients, Cancer Pathways, 36–56. London: Palgrave Macmillan UK, 2012. http://dx.doi.org/10.1057/9781137272089_3.

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Kutcher, Gerald. "A Case Study in Human Experimentation: The Patient as Subject, Object and Victim." In Cancer Patients, Cancer Pathways, 57–77. London: Palgrave Macmillan UK, 2012. http://dx.doi.org/10.1057/9781137272089_4.

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Johnstone, Emm Barnes. "Captain Chemo and Mr Wiggly: Patient Information for Children with Cancer in the Late Twentieth Century." In Cancer Patients, Cancer Pathways, 78–100. London: Palgrave Macmillan UK, 2012. http://dx.doi.org/10.1057/9781137272089_5.

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Conference papers on the topic "Cancer patients as artists"

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Herzog, Thomas, John Hays, Kathleen Moore, Panagiotis Konstantinopoulos, Lucy Gilbert, Bradley Monk, David O’Malley, et al. "TP025/#1399 Artistry-7: phase 3 multicenter study of nemvaleukin alfa plus pembrolizumab versus chemotherapy in patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer." In IGCS 2022 Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/ijgc-2022-igcs.534.

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Herzog, Thomas J., Kathleen Moore, Panagiotis A. Konstantinopoulos, Lucy Gilbert, John L. Hays, Bradley J. Monk, David M. O’Malley, et al. "2022-RA-687-ESGO ARTISTRY-7: phase 3, multicenter study of nemvaleukin alfa plus pembrolizumab versus chemotherapy in patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer (GOG-3063; ENGOT-OV68)." In ESGO 2022 Congress. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/ijgc-2022-esgo.546.

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Tenev, K., and M. Hristova. "Ototoxicity by some Cancer Patients." In Abstract- und Posterband – 90. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Digitalisierung in der HNO-Heilkunde. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1686522.

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Hidalgo Morales, Kattyta Patricia, and Lenier Leon Baryolo. "Nutrition in childhood cancer patients." In 1er Congreso Universal de las Ciencias y la Investigación Medwave 2022;. Medwave Estudios Limitada, 2022. http://dx.doi.org/10.5867/medwave.2022.s2.uta010.

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Das, Anita, Arild Faxvaag, and Dag Svanæs. "Interaction design for cancer patients." In the 2011 annual conference. New York, New York, USA: ACM Press, 2011. http://dx.doi.org/10.1145/1978942.1978946.

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Kirana, W. T., and G. A. Desianti. "Bacterial Colonizationin Lung Cancer Patients." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3380.

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Bravo, Maria L., Pamela Gonzalez, Sumie Kato, Marcelo Garrido, Jorge Brañes, Javier Pizarro, Maria Isabel Barriga, et al. "Abstract 1187: Personalized cancer therapy for ovarian cancer patients." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-1187.

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Aggarwal, S., R. Sharma, J. Bhoemick, M. Singh, and A. Aggarwal. "Abstract P2-14-14: Voice of cancer patients (VoCP): Analysis of experiences of cancer patients undergoing breast cancer surgery." In Abstracts: 2018 San Antonio Breast Cancer Symposium; December 4-8, 2018; San Antonio, Texas. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-p2-14-14.

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Dimitra, Lekka, Aggeliki Rapti, Dimitra Karkania, Argyri Evmolpidi, George Moussas, and Athanasios Karkanias. "Distress thermometer in lung cancer patients." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa3072.

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Savitri, Wenny, and Amin Haryati. "Psychosocial Distress in Breast Cancer Patients." In International Conference on Health and Medical Sciences (AHMS 2020). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/ahsr.k.210127.032.

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Reports on the topic "Cancer patients as artists"

1

Novinger, Leah. Identification of Autoantibodies to Breast Cancer Antigens in Breast Cancer Patients. Fort Belvoir, VA: Defense Technical Information Center, October 2011. http://dx.doi.org/10.21236/ada555908.

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Fisher, Richard. Early Diagnosis, Treatment and Care of Cancer Patients. Fort Belvoir, VA: Defense Technical Information Center, September 2008. http://dx.doi.org/10.21236/ada494164.

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Dy, Sydney M., Arjun Gupta, Julie M. Waldfogel, Ritu Sharma, Allen Zhang, Josephine L. Feliciano, Ramy Sedhom, et al. Interventions for Breathlessness in Patients With Advanced Cancer. Agency for Healthcare Research and Quality (AHRQ), November 2020. http://dx.doi.org/10.23970/ahrqepccer232.

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Objectives. To assess benefits and harms of nonpharmacological and pharmacological interventions for breathlessness in adults with advanced cancer. Data sources. We searched PubMed®, Embase®, CINAHL®, ISI Web of Science, and the Cochrane Central Register of Controlled Trials through early May 2020. Review methods. We included randomized controlled trials (RCTs) and observational studies with a comparison group evaluating benefits and/or harms, and cohort studies reporting harms. Two reviewers independently screened search results, serially abstracted data, assessed risk of bias, and graded strength of evidence (SOE) for key outcomes: breathlessness, anxiety, health-related quality of life, and exercise capacity. We performed meta-analyses when possible and calculated standardized mean differences (SMDs). Results. We included 48 RCTs and 2 retrospective cohort studies (4,029 patients). The most commonly reported cancer types were lung cancer and mesothelioma. The baseline level of breathlessness varied in severity. Several nonpharmacological interventions were effective for breathlessness, including fans (SMD -2.09 [95% confidence interval (CI) -3.81 to -0.37]) (SOE: moderate), bilevel ventilation (estimated slope difference -0.58 [95% CI -0.92 to -0.23]), acupressure/reflexology, and multicomponent nonpharmacological interventions (behavioral/psychoeducational combined with activity/rehabilitation and integrative medicine). For pharmacological interventions, opioids were not more effective than placebo (SOE: moderate) for improving breathlessness (SMD -0.14 [95% CI -0.47 to 0.18]) or exercise capacity (SOE: moderate); most studies were of exertional breathlessness. Different doses or routes of administration of opioids did not differ in effectiveness for breathlessness (SOE: low). Anxiolytics were not more effective than placebo for breathlessness (SOE: low). Evidence for other pharmacological interventions was limited. Opioids, bilevel ventilation, and activity/rehabilitation interventions had some harms compared to usual care. Conclusions. Some nonpharmacological interventions, including fans, acupressure/reflexology, multicomponent interventions, and bilevel ventilation, were effective for breathlessness in advanced cancer. Evidence did not support opioids or other pharmacological interventions within the limits of the identified studies. More research is needed on when the benefits of opioids may exceed harms for broader, longer term outcomes related to breathlessness in this population.
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Jordan, Craig T., and Richard I. Fisher. Early Diagnosis, Treatment, and Care of Cancer Patients. Fort Belvoir, VA: Defense Technical Information Center, September 2010. http://dx.doi.org/10.21236/ada541190.

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Fisher, Richard. Early Diagnosis, Treatment, and Care of Cancer Patients. Fort Belvoir, VA: Defense Technical Information Center, September 2009. http://dx.doi.org/10.21236/ada523889.

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Fisher, Fichard I., and Craig T. Jordan. Early Diagnosis, Treatment and Care of Cancer Patients. Fort Belvoir, VA: Defense Technical Information Center, September 2012. http://dx.doi.org/10.21236/ada569436.

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Backonja, Miroslav. Pain Management Skills for Minority Breast Cancer Patients. Fort Belvoir, VA: Defense Technical Information Center, October 2002. http://dx.doi.org/10.21236/ada420284.

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Pohl, R. Vincent. Medical Innovation and the Employment of Cancer Patients. W.E. Upjohn Institute, June 2019. http://dx.doi.org/10.17848/pb2019-11.

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Pohl, R. Vincent. Medical Innovation and the Employment of Cancer Patients. W.E. Upjohn Institute, June 2019. http://dx.doi.org/10.17848/pb2019-12.

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Fisher, Richard, and Craig T. Jordon. Early Diagnosis, Treatment and Care of Cancer Patients. Fort Belvoir, VA: Defense Technical Information Center, September 2011. http://dx.doi.org/10.21236/ada555799.

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