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Journal articles on the topic 'Cancer-related pain relief'

Author: Grafiati

Published: 4 June 2021

Last updated: 13 February 2022

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1

KIMURA, RIEKO, SAORI HASHIGUCHI, MASAKO KAWA, et al. "Pain management and related factors in advanced cancer patients who initiated opioid therapy in an outpatient setting." Palliative and Supportive Care 3, no. 4 (2005): 301–9. http://dx.doi.org/10.1017/s1478951505050467.

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Objective: The aim of this study was to clarify the state of pain management in Japanese patients with advanced cancer who initiated opioid therapy in an outpatient setting.Methods: Interview surveys using questionnaires were conducted and medical records were reviewed. Pain relief was defined as >33% decrease in worst pain intensity score, and significance of early pain relief was investigated in terms of changing self-efficacy for activities of daily living (ADL). Factors related to early pain relief were also investigated.Results: The study was conducted between June and December 2003, o

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Dupoiron, Denis, Damien Leblanc, Sybille Demelliez-Merceron, et al. "Optimizing Initial Intrathecal Drug Ratio for Refractory Cancer-Related Pain for Early Pain Relief. A Retrospective Monocentric Study." Pain Medicine 20, no. 10 (2019): 2033–42. http://dx.doi.org/10.1093/pm/pnz096.

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Abstract Objective Intrathecal (IT) drug delivery has shown its efficiency in treating refractory cancer pain, but switching opioids from the systemic to the intrathecal route is a challenging phase. Moreover, associations are widely used and recommended. Few data deal with the initial dosage of each drug. Analyzing conversion factors and initial dosages used in intrathecal therapy seems essential to decreasing the length of titration and to delivering quick pain relief to patients. Methods We retrospectively analyzed data from consecutive adult patients implanted with an intrathecal device fo

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3

Filshie, Jacqueline, Katherine Penn, Sue Ashley, and Carol L. Davis. "Acupuncture for the relief of cancer-related breathlessness." Palliative Medicine 10, no. 2 (1996): 145–50. http://dx.doi.org/10.1177/026921639601000209.

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Spiegel, Matthew A., Lee Hingula, Grant H. Chen, Aron Legler, Vinay Puttanniah, and Amitabh Gulati. "The Use of L2 and L3 Lumbar Sympathetic Blockade for Cancer-Related Pain, an Experience and Recommendation in the Oncologic Population." Pain Medicine 21, no. 1 (2019): 176–84. http://dx.doi.org/10.1093/pm/pnz142.

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Abstract Objective The sympathetic nervous system has a recognized role in transmission of pain, and the lumbar sympathetic blockade is intended to provide analgesia. We share our experiences of lumbar sympathetic blockade in the treatment of cancer-related pain. Methods We performed a retrospective analysis of patients with cancer-related pain in the back, abdomen, pelvis, or legs treated at Memorial Sloan Kettering Cancer Center between 2000 and 2018 undergoing lumbar sympathetic blockade at L2 or L3. Blocks were accomplished by injection of local anesthetic or local anesthetic with steroid

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Lee, Hyangsook, Katja Schmidt, and Edzard Ernst. "Acupuncture for the relief of cancer-related pain - a systematic review." European Journal of Pain 9, no. 4 (2005): 437. http://dx.doi.org/10.1016/j.ejpain.2004.10.004.

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Nauta, Haring J. W., Vicki M. Soukup, Roderic H. Fabian, et al. "Punctate midline myelotomy for the relief of visceral cancer pain." Journal of Neurosurgery: Spine 92, no. 2 (2000): 125–30. http://dx.doi.org/10.3171/spi.2000.92.2.0125.

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Object. This study offers clinical support for the concept that neurosurgical interruption of a midline posterior column pathway by performing a punctate midline myelotomy (PMM) provides significant pain relief without causing adverse neurological sequelae in cancer patients with visceral pain refractory to other therapies. Methods. A PMM of the posterior columns was performed in six cancer patients in whom visceral pain had been refractory to other therapies. The cause of the visceral pain was related to residual, progressive, or recurrent local cancer or postirradiation effects. Clinical eff

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Scarpi, Emanuela, Daniele Calistri, Pål Klepstad, et al. "Clinical and Genetic Factors Related to Cancer‐Induced Bone Pain and Bone Pain Relief." Oncologist 19, no. 12 (2014): 1276–83. http://dx.doi.org/10.1634/theoncologist.2014-0174.

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Raslan, Ahmed M. "Percutaneous Computed Tomography-guided Radiofrequency Ablation of Upper Spinal Cord Pain Pathways for Cancer-Related Pain." Operative Neurosurgery 62, suppl_1 (2008): ONS226—ONS234. http://dx.doi.org/10.1227/01.neu.0000317397.16089.f5.

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Abstract Objective: The author presents data to support the continued need for ablative procedures, particularly cordotomy, in the management of cancer-related pain. Methods: Fifty-one patients with cancer-related body or face pain were treated with computed tomography-guided radiofrequency ablation of the spinothalamic tract or trigeminal tract nucleus in the upper cervical region of the spinal cord. Forty-one patients underwent a unilateral cervical cordotomy, and 10 patients underwent a trigeminal tractotomy–nucleotomy. Three methods to assess patient pain were used: degree of pain relief,

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King, Kelly. "A Review of the Effects of Guided Imagery on Cancer Patients with Pain." Complementary health practice review 15, no. 2 (2010): 98–107. http://dx.doi.org/10.1177/1533210110388113.

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Over half of the patients diagnosed with cancer suffer from pain. Often, analgesic medications do not completely relieve the pain and alternative measures are sought out for relief. Mind—body techniques such as guided imagery (GI) have been thought to be helpful and used as an adjuvant to pain relief. This article evaluates and summarizes studies performed from 2001 to 2008, which investigated the use of GI for relief of cancer pain. Electronic databases were searched with the keywords cancer pain, visualization, and guided imagery, for any studies utilizing GI with an outcome measure of pain.

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Sica, Antonello, Beniamino Casale, Maria Teresa Di Dato, et al. "Cancer- and non-cancer related chronic pain: from the physiopathological basics to management." Open Medicine 14, no. 1 (2019): 761–66. http://dx.doi.org/10.1515/med-2019-0088.

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AbstractThe prevalence of chronic pain is between 33% to 64% and is due to cancer pain, but it has also been observed in non-cancer patients. Chronic pain is associated with lower quality of life and higher psychological distress and depressive/anxiety disorders in patients without a history of disorder.In this study we evaluated in clinical practice the effectiveness of the intrathecal pump in 140 patients who underwent pain therapy at our Center. These patients were consecutively enrolled from January 2010 to July 2018.Follow-up was carried out over these eight years regarding the infusion m

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Lee, H., K. Schmidt, and E. Ernst. "A systematic review of acupuncture for the relief of cancer-related pain." Focus on Alternative and Complementary Therapies 8, no. 4 (2010): 511–12. http://dx.doi.org/10.1111/j.2042-7166.2003.tb04026.x.

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Kane, Chris M., Matthew R. Mulvey, Sophie Wright, Cheryl Craigs, Judy M. Wright, and Michael I. Bennett. "Opioids combined with antidepressants or antiepileptic drugs for cancer pain: Systematic review and meta-analysis." Palliative Medicine 32, no. 1 (2017): 276–86. http://dx.doi.org/10.1177/0269216317711826.

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Background: Combining antidepressant or antiepileptic drugs with opioids has resulted in increased pain relief when used for neuropathic pain in non-cancer conditions. However, evidence to support their effectiveness in cancer pain is lacking. Aim: To determine if there is additional benefit when opioids are combined with antidepressant or antiepileptic drugs for cancer pain. Design: Systematic review and meta-analysis. Randomised control trials comparing opioid analgesia in combination with antidepressant or antiepileptic drugs versus opioid monotherapy were sought. Data on pain and adverse e

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Reis-Pina, Paulo, Peter G. Lawlor, and António Barbosa. "Cancer-Related Pain Management and the Optimal Use of Opioids." Acta Médica Portuguesa 28, no. 3 (2015): 376. http://dx.doi.org/10.20344/amp.5801.

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<p>Pain relief is vital to the treatment of cancer. Despite the widespread use and recognition of clinical recommendations for the management of cancer-related pain, avoidable suffering is still prevalent in patients with malignant disease. A gap exists between what is known about pain medical management and actual practices of patients, caregivers, healthcare professionals and institutions. Opioids are the pillar of the medical management of moderate to severe pain. The prescription of opioid analgesics – by a registered medical practitioner for absolute pain control – is a legitimate p

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Ersek, Mary, and Betty R. Ferrell. "Providing Relief from Cancer Pain by Assisting in the Search for Meaning." Journal of Palliative Care 10, no. 4 (1994): 15–22. http://dx.doi.org/10.1177/082585979401000404.

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Pain is a common, distressing symptom experienced by cancer patients and their family caregivers. An important aspect of coping with cancer pain is the ability to make meaning of the experience. This paper provides an overview of the literature related to meaning-making processes utilized by people experiencing cancer. It also presents an integrated approach to assisting patients and their family caregivers with the meaning-making process associated with cancer pain. Approaches to intervening are integrated within a model developed through previous research.

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Firdousi, Faizul Hasan, Dhananjaya Sharma, and V. K. Raina. "Palliation by Coeliac Plexus Block for Upper Abdominal Visceral Cancer Pain." Tropical Doctor 32, no. 4 (2002): 224–26. http://dx.doi.org/10.1177/004947550203200413.

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Palliation of cancer related pain is one of the major concerns of patients suffering from cancer of the upper abdominal organs. The non-availability of imaging techniques to guide needle placement prompted us to use a blind technique of neurolytic coeliac plexus block. Thirty consecutive patients with intractable pain, due to documented inoperable upper abdominal visceral cancers, underwent neurolytic coeliac plexus block by blind percutaneous retrocrural unilateral neurolysis. The severity of pain was documented on a 0–10 visual analogue scale (VAS) performed pre-block and post-block at 1 day

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Stephen, C. Saris, M. Silver Jon, F. S. Vieira Jose, and S. Nashold Blaine. "Sacrococcygeal Rhizotomy for Perineal Pain." Neurosurgery 19, no. 5 (1986): 789–93. http://dx.doi.org/10.1227/00006123-198611000-00012.

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Abstract Chronic pain in the perineum is a difficult neurosurgical problem. This article evaluates the effectiveness of sacrococcygeal rhizotomy in 28 patients who had cancer-related pain or coccydynia, underwent rhizotomy, and were followed for an average of 3 years. Good pain relief was obtained in 53% (10 of 19 patients) with malignant pain, as opposed to 22% (2 of 9 patients) with nonmalignant pain. Sacral rhizotomy is a reasonable treatment for cancer-related perineal pain, but it is ineffective for coccydynia and other benign perineal pain problems.

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Rykowski, Jan J., and Maciej Hilgier. "Efficacy of Neurolytic Celiac Plexus Block in Varying Locations of Pancreatic Cancer." Anesthesiology 92, no. 2 (2000): 347. http://dx.doi.org/10.1097/00000542-200002000-00014.

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Background Neurolytic celiac plexus block (NCPB) is an effective way of treating severe pain in some patients with pancreatic malignancy. However, there are no studies to date that evaluate the effectiveness of NCPB related to the site of primary pancreas cancer. The aim of the study was to assess the effectiveness of NCPB in pancreatic cancer pain, depending on the location of the pancreatic tumor. Methods The prospective study was conducted in 50 consecutive patients diagnosed with pancreatic cancer. The patients were categorized into two different groups depending on tumor localization: gro

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González-Cano, Rafael, M. Carmen Ruiz-Cantero, Miriam Santos-Caballero, Carlos Gómez-Navas, Miguel Á. Tejada, and Francisco R. Nieto. "Tetrodotoxin, a Potential Drug for Neuropathic and Cancer Pain Relief?" Toxins 13, no. 7 (2021): 483. http://dx.doi.org/10.3390/toxins13070483.

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Tetrodotoxin (TTX) is a potent neurotoxin found mainly in puffer fish and other marine and terrestrial animals. TTX blocks voltage-gated sodium channels (VGSCs) which are typically classified as TTX-sensitive or TTX-resistant channels. VGSCs play a key role in pain signaling and some TTX-sensitive VGSCs are highly expressed by adult primary sensory neurons. During pathological pain conditions, such as neuropathic pain, upregulation of some TTX-sensitive VGSCs, including the massive re-expression of the embryonic VGSC subtype NaV1.3 in adult primary sensory neurons, contribute to painful hypers

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Schmidt-Hansen, Mia, Michael I. Bennett, Stephanie Arnold, Nathan Bromham, and Jennifer S. Hilgart. "Efficacy, tolerability and acceptability of oxycodone for cancer-related pain in adults: an updated Cochrane systematic review." BMJ Supportive & Palliative Care 8, no. 2 (2018): 117–28. http://dx.doi.org/10.1136/bmjspcare-2017-001457.

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ObjectivesTo assess the efficacy, tolerability and acceptability of oxycodone for cancer pain in adultsMethodsWe searched CENTRAL, MEDLINE, MEDLINE In-Process, Embase, SCI, Conference Proceedings Citation Index-Science, BIOSIS, PsycINFO and four trials registries to November 2016.ResultsWe included 23 randomised controlled trials with 2144 patients analysed for efficacy and 2363 for safety. Meta-analyses showed no significant differences between controlled-release (CR) and immediate-release oxycodone in pain intensity or adverse events but did show significantly better pain relief after treatm

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Perez, Jordi, Sara Olivier, Emmanouil Rampakakis, Manuel Borod, and Yoram Shir. "The McGill University Health Centre Cancer Pain Clinic: A Retrospective Analysis of an Interdisciplinary Approach to Cancer Pain Management." Pain Research and Management 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/2157950.

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Context. The McGill University Health Center (MUHC) Cancer Pain Clinic offers an interdisciplinary approach to cancer pain management for patients. The core team includes a nurse clinician specialist in oncology and palliative care, a palliativist, an anaesthetist, and a radiation oncologist. This tailored approach includes pharmacological and nonpharmacological therapies offered concurrently in an interdisciplinary fashion.Objectives. Description of the interdisciplinary MUHC cancer pain approach and analysis of treatments and outcomes.Methods. A retrospective analysis of new outpatients comp

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Hayek, Salim M. "Intrathecal Therapy for Cancer and Non-Cancer Pain." Pain Physician 3;14, no. 3;5 (2011): 219–48. http://dx.doi.org/10.36076/ppj.2011/14/219.

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Background: Intrathecal drug infusion therapy is usually considered when spinal-acting analgesics or antispasmodics administered via the oral or transdermal routes fail to control patients’ pain or are associated with unacceptable side effects. The intrathecal administration of centrally acting agents bypasses the blood-brain-barrier resulting in much higher cerebrospinal fluid (CSF) concentrations while using reduced amounts of medication to achieve equipotent doses. The intrathecal approach is associated with higher rates of satisfactory pain relief and lower rates of treatment failures and

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Pinto, Mario De. "Peripheral and Neuraxial Chemical Neurolysis for the Management of Intractable Lower Extremity Pain in a Patient with Terminal Cancer." July 2015 18;4, no. 4;18 (2015): E651—E656. http://dx.doi.org/10.36076/ppj.2015/18/e651.

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We present the case of a 74-year-old man with Stage IV metastatic, multifocal, malignant fibrous histiocytoma (T2b, N1, M1, G4) invading the proximal area of the left lower extremity and resulting in intractable neuropathic pain along the distribution of the femoral nerve. He described the pain as being so severe to cause inability to ambulate without assistance or to sleep in a supine or prone position. After a spinal cord stimulation trial and a trial of intrathecal (IT) hydromorphone, both performed at an outside institution, had failed to achieve adequate pain relief, we decided to perform

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Rahman, Abed. "Low Volume Neurolytic Retrocrural Celiac Plexus Block for Visceral Cancer Pain: Retrospective Review of 507 Patients with Severe Malignancy Related Pain Due to Primary Abdominal Cancer or Metastatic Disease." January 2018 1, no. 21;1 (2018): 497–504. http://dx.doi.org/10.36076/ppj.2018.5.497.

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Background: Abdominal pain from primary cancer or metastatic disease is a significant cause of pain for patients undergoing treatment for the disease. Patient’s pain may be resistant to conventional analgesics. The need for timely pain relief in order to facilitate further care in the cancer treatment plan should be a priority. Objectives: The aim of this retrospective observational review was to assess the relief given with a low volume neurolytic retrocrural celiac plexus nerve block, the duration of the procedure, the duration of relief, the reduction in daily opioid consumption, and the im

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Mateus, Dinis, Joana Marto, Patrícia Trindade, et al. "Improved Morphine-Loaded Hydrogels for Wound-Related Pain Relief." Pharmaceutics 11, no. 2 (2019): 76. http://dx.doi.org/10.3390/pharmaceutics11020076.

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The use of morphine applied topically to painful wounds has potential advantages, such as dose reduction, fewer side effects and compound formulations, have been proposed for this purpose. Given the potential high impact of drug product quality on a patient’s health, the aim of the present study was to develop two stable sterile hydrogels containing morphine hydrochloride, intended for topical application on painful wounds. Two carboxymethylcellulose sodium-based hydrogels were prepared containing 0.125% w/w (F1-MH semi-solid formulation) and 1.0% w/w (F2-MH fluid formulation) morphine hydroch

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LeBlanc, Julia K., Susan Rawl, Michelle Juan, et al. "Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis in Pancreatic Cancer: A Prospective Pilot Study of Safety Using 10 mL versus 20 mL Alcohol." Diagnostic and Therapeutic Endoscopy 2013 (January 8, 2013): 1–6. http://dx.doi.org/10.1155/2013/327036.

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Background. The dose of alcohol used in EUS-CPN is not standardized. The objective was to compare the safety of 20 mL alcohol versus 10 mL alcohol during EUS-CPN for patients with pancreatic cancer-related pain. Methods. 20 patients were selected to receive 10 mL or 20 mL of alcohol during EUS-CPN. Followup was done at baseline, 24 hours, and weekly. Health-related quality of life (HRQoL) was assessed at baseline, week 2, week 4, and every 4 weeks thereafter until pain returned. Results. There were no major complications in both groups. Minor self-limited adverse effects were seen in 6 (30%) s

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Penn, Richard D., and Judith A. Paice. "Chronic intrathecal morphine for intractable pain." Journal of Neurosurgery 67, no. 2 (1987): 182–86. http://dx.doi.org/10.3171/jns.1987.67.2.0182.

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✓ Forty-three patients with intractable pain received intrathecal morphine delivered by implanted continuous-infusion (Infusaid) or programmable (Medtronic) devices. In 35 patients the pain was due to cancer, and eight patients had chronic nonmalignant pain. The origin of the nonmalignant pain included lumbar arachnoiditis, multiple sclerosis, severe osteoporosis resulting in a thoracic compression fracture, and intractable pain as a consequence of cancer therapy in individuals cured of their disease. Twenty-eight (80%) of the patients with cancer-related pain experienced excellent or good rel

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Tuem, Kald Beshir, Leake Gebremeskel, Kibrom Hiluf, Kbrom Arko, and Haftom Gebregergs Hailu. "Adequacy of Cancer-Related Pain Treatments and Factors Affecting Proper Management in Ayder Comprehensive Specialized Hospital, Mekelle, Ethiopia." Journal of Oncology 2020 (September 24, 2020): 1–10. http://dx.doi.org/10.1155/2020/2903542.

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Background. Cancer-related pain (CRP) is a major problem with a potential negative impact on quality of life of the patients and their caregivers. Purpose. To assess the adequacy of cancer-related pain management in Ayder Comprehensive Specialized Hospital (ACSH). Methodology. A facility-based cross-sectional study design was conducted in ACSH from January to March 2019. A well-structured professional-assisted questionnaire using Brief Pain Inventory-Short Form (BPI-SF) was used to collect data concerning the severity of pain, functioning interference, and adequacy of pain management in cancer

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Weick, J. K., L. Tremmel, J. Messina, and R. K. Portenoy. "Finding an appropriate dose of fentanyl effervescent buccal tablets for relief of cancer-related breakthrough pain." Journal of Clinical Oncology 24, no. 18_suppl (2006): 8564. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.8564.

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8564 Background: The recommended dose of a short-acting oral opioid used to treat cancer-related breakthrough pain (BTP) is 5%-15% of the equianalgesic around-the-clock (ATC) opioid dose used to control persistent pain; however, this dosing strategy may not be successful when oral transmucosal fentanyl citrate is used. The applicability of this strategy to fentanyl effervescent buccal tablets (FEBT) use was assessed as part of a multicenter study in opioid-treated patients with cancer BTP. Methods: This double-blind, randomized, placebo-controlled, crossover study required 63 evaluable patient

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Ahmed, Doaa Gomaa. "Superior Hypogastric Plexus Combined with Ganglion Impar Neurolytic Blocks for Pelvic and/or Perineal Cancer Pain Relief." Pain Physician 18;1, no. 1;1 (2015): E49—E56. http://dx.doi.org/10.36076/ppj/2015.18.e49.

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Background: The superior hypogastric plexus (SHGP) carries afferents from the viscera of the lower abdomen and pelvis. Neurolytic block of this plexus is used for reducing pain resulting from malignancy in these organs. The ganglion impar (GI) innervats the perineum, distal rectum, anus, distal urethra, vulva, and distal third of the vagina. Different approaches to the ganglion impar neurolysis have been described in the literature. Objectives: To assess the feasibility, safety, and efficacy of combining the block of the SHGP through the postero-median transdiscal approach with the GI block by

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Viswanathan, Ashwin, Viraat Harsh, Erlick A. C. Pereira, and Tipu Z. Aziz. "Cingulotomy for medically refractory cancer pain." Neurosurgical Focus 35, no. 3 (2013): E1. http://dx.doi.org/10.3171/2013.6.focus13236.

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Object Cingulotomy has been reported in the literature as a potential treatment option for refractory cancer-related pain. However, the optimal candidates for this intervention and the outcomes are not well characterized. The goal of this study was to review the available literature on cingulotomy, specifically for cancer-related pain. Methods A search of PubMed, PubMed Central, the Cochrane Library, and MEDLINE was performed to identify all articles discussing cingulotomy for cancer pain. The text strings “cingul*” and “pain” were separated by the Boolean AND operator, and used to perform the

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Ma, Xiaoxiao, Yuhan Lu, Hong Yang, et al. "Relationships between patient-related attitudinal barriers, analgesic adherence and pain relief in Chinese cancer inpatients." Supportive Care in Cancer 28, no. 7 (2019): 3145–51. http://dx.doi.org/10.1007/s00520-019-05082-8.

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Sandner-Kiesling, Andreas. "IL-7, IL-18, MCP-1, MIP1-β, and OPG as Biomarkers for Pain Treatment Response in Patients with Cancer". Pain Physician 6;15, № 6;12 (2012): 499–510. http://dx.doi.org/10.36076/ppj.2012/15/499.

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Background: Pain is one of the most common symptoms in patients suffering from advanced cancer and receiving palliative care and is often responsible for a poor quality of life. To date, there exists no published correlation between biological, measurable biomarkers and pain intensity. Objectives: The primary objective was to search and identify pain-associated cytokines (biomarkers) correlating with changes in numeric rating scale (NRS) pain scores in patients with cancer before and after pain treatment. The secondary objectives were to assess cytokine serum level differences between patients

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Hu, Caiqiong, Haibo Zhang, Wanyin Wu, et al. "Acupuncture for Pain Management in Cancer: A Systematic Review and Meta-Analysis." Evidence-Based Complementary and Alternative Medicine 2016 (February 10, 2016): 1–13. http://dx.doi.org/10.1155/2016/1720239.

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Objective. To evaluate the effectiveness and safety of acupuncture for cancer-related pain. Methods. A systematic review of literatures published from database inception to February 2015 was conducted in eight databases. RCTs involving acupuncture for treatment of cancer-related pain were identified. Two researchers independently performed article selection, data extraction, and quality assessment of data. Results. 1,639 participants in twenty RCTs were analyzed. All selected RCTs were associated with high risk of bias. Meta-analysis indicated that acupuncture alone did not have superior pain-

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Charalambous, Andreas, Marios Zorpas, Constantina Cloconi, and Yolanda Kading. "Healthcare professionals’ perceptions on the use of opioid analgesics for the treatment of cancer-related pain in Cyprus: A mixed-method study." SAGE Open Medicine 7 (January 2019): 205031211984182. http://dx.doi.org/10.1177/2050312119841823.

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Objectives: Pain is considered the most common and debilitating symptom reported by patients affected by cancer, and opioids are at the front line for its effective management. However, the appropriate use of opioids can be limited by healthcare professionals’ perceptions on opioids. Therefore, the aim of this study was to explore their perceptions on the use of opioids medication. Methods: This was a study of sequential mixed-method design conducted in Cyprus. As part of the quantitative phase of the study, the Barriers to Opioid Analgesic Availability Test questionnaire was completed by 73 p

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Hsu, Hui-Ching, Tzu-Yao Liao, Long-Sun Ro, Yu-Hsiang Juan, and Chuang-Chi Liaw. "Differences in Pain Intensity of Tumors Spread to the Anterior versus Anterolateral/Lateral Portions of the Vertebral Body Based on CT Scans." Pain Research and Management 2019 (May 13, 2019): 1–6. http://dx.doi.org/10.1155/2019/9387941.

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We investigated whether the intensity of cancer pain differs for malignant tumors that have spread to anterior or anterolateral/lateral portions of the vertebral body. We hypothesize that tumor spread to the anterolateral/lateral vertebral body elicits more serious pain due to increased irritation of the spinal nerve. The selection criteria were as follows: (1) advanced or metastatic solid tumor; (2) radicular pain without extremity weakness; (3) malignant lesions anteriorly, anterolaterally, or laterally located at the vertebral body either spread locoregionally or over a greater distance via

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Jiang, Jingru, Yi Li, Qingyu Shen, et al. "Effect of Pregabalin on Radiotherapy-Related Neuropathic Pain in Patients With Head and Neck Cancer: A Randomized Controlled Trial." Journal of Clinical Oncology 37, no. 2 (2019): 135–43. http://dx.doi.org/10.1200/jco.18.00896.

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Purpose Neuropathic pain is an unavoidable treatment-related adverse event among patients with head and neck cancer who are undergoing radiotherapy. We aimed to test the efficacy and safety of pregabalin versus placebo in the treatment of radiotherapy-related neuropathic pain. Patients and Methods This randomized, double-blind, placebo-controlled trial was conducted in four centers in China. Eligible patients with a mean pain intensity score of 4 or more on an 11-point numeric rating scale were randomly assigned to receive either active treatment with a flexible dose of pregabalin or placebo f

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Martin, Emily J., Andrew R. Bruggeman, Vinit V. Nalawade, et al. "Palliative Radiotherapy Versus Esophageal Stent Placement in the Management of Patients With Metastatic Esophageal Cancer." Journal of the National Comprehensive Cancer Network 18, no. 5 (2020): 569–74. http://dx.doi.org/10.6004/jnccn.2019.7524.

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Background: Patients with advanced esophageal cancer often experience pain and dysphagia, yet the optimal palliative management remains unclear. This retrospective study evaluated outcomes and adverse effects of palliative radiotherapy (RT) compared with esophageal stenting among a cohort of U.S. veterans with metastatic esophageal cancer. Patients and Methods: We identified 1,957 veterans in the United States with metastatic esophageal cancer who received palliative RT to the esophagus or esophageal stenting, and assessed the risks of severe adverse effects, including esophageal fistula forma

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Kim, Kyung Soo, Sarah Loring, and Kristine Kwekkeboom. "Use of Art-Making Intervention for Pain and Quality of Life Among Cancer Patients: A Systematic Review." Journal of Holistic Nursing 36, no. 4 (2017): 341–53. http://dx.doi.org/10.1177/0898010117726633.

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Background: Although pain is one of the most prevalent symptoms among cancer patients, medications do not always result in sufficient pain relief. Furthermore, these medications only address the physical component of pain. Art making, a holistic approach, may distract the user’s attention from pain and allow expression of the nonphysical (e.g., psychological, spiritual) components of pain. The purpose of this systematic review was to evaluate evidence for the efficacy of art-making interventions in reducing pain and improving health-related quality of life (QoL) among cancer patients. Method:

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Kim, Young Jin, Kyung Tae Kim, and Chan Woo Song. "Neurolytic Blockade of the Ganglion Impar for Relief of Cancer-Related Perianal Pain: A case report." Korean Journal of Anesthesiology 33, no. 4 (1997): 750. http://dx.doi.org/10.4097/kjae.1997.33.4.750.

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Falk, Sarah, Maria Uldall, and Anne-Marie Heegaard. "The Role of Purinergic Receptors in Cancer-Induced Bone Pain." Journal of Osteoporosis 2012 (2012): 1–12. http://dx.doi.org/10.1155/2012/758181.

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Cancer-induced bone pain severely compromises the quality of life of many patients suffering from bone metastasis, as current therapies leave some patients with inadequate pain relief. The recent development of specific animal models has increased the understanding of the molecular and cellular mechanisms underlying cancer-induced bone pain including the involvement of ATP and the purinergic receptors in the progression of the pain state. In nociception, ATP acts as an extracellular messenger to transmit sensory information both at the peripheral site of tissue damage and in the spinal cord. S

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Hurwitz, Mark, Joshua E. Meyer, Dimitri Iozeffi, et al. "Magnetic resonance guided focused ultrasound surgery for palliation of painful bone metastasis: Results of a multicenter phase III trial." Journal of Clinical Oncology 31, no. 15_suppl (2013): 9500. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.9500.

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9500 Background: Pain due to bone metastases is a common cause of cancer-related morbidity. Magnetic resonance guided focused ultrasound surgery (MRgFUS) is a non-invasive approach to thermal tissue ablation. This multi-center phase III trial assessed efficacy of MRgFUS compared with sham treatment to alleviate pain due to bone metastases. Methods: Subjects with a painful bone metastasis amenable to MRgFUS treatment for whom radiation therapy was ineffective or contraindicated were randomized 3:1 to MRgFUS or sham treatment in a single blind design. Un-blinding of sham subjects who did not exp

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Farrar, John T., Rosemary C. Polomano, Jesse A. Berlin, and Brian L. Strom. "A Comparison of Change in the 0–10 Numeric Rating Scale to a Pain Relief Scale and Global Medication Performance Scale in a Short-term Clinical Trial of Breakthrough Pain Intensity." Anesthesiology 112, no. 6 (2010): 1464–72. http://dx.doi.org/10.1097/aln.0b013e3181de0e6d.

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Background Pain intensity is commonly reported using a 0-10 Numeric Rating Scale in pain clinical trials. Analysis of the change on the Pain Intensity Numerical Rating Scale as a proportion has most consistently correlated with clinically important differences reported on the patient's global impression of change. The correlation of data from patients with breakthrough pain with a Pain Relief Scale and a different global outcome measures will extend our understanding of these measures. Methods Data were obtained from the open titration phase of a multiple crossover, randomized, double-blind cl

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Xu, Xiangfeng, Tim Luckett, Alex Yueping Wang, Melanie Lovell, and Jane L. Phillips. "Cancer pain management needs and perspectives of patients from Chinese backgrounds: a systematic review of the Chinese and English literature." Palliative and Supportive Care 16, no. 6 (2018): 785–99. http://dx.doi.org/10.1017/s1478951517001171.

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AbstractObjectiveMore than half of all cancer patients experience unrelieved pain. Culture can significantly affect patients’ cancer pain-related beliefs and behaviors. Little is known about cultural impact on Chinese cancer patients’ pain management. The objective of this review was to describe pain management experiences of cancer patients from Chinese backgrounds and to identify barriers affecting their pain management.MethodA systematic review was conducted adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Studies were included if they reported pain

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Uchida, Ken-ichiro. "Radiofrequency Treatment of the Thoracic Paravertebral Nerve Combined with Glucocorticoid for Refractory Neuropathic Pain Following Breast Cancer Surgery." Pain Physician 4;12, no. 4;7 (2009): E277—E283. http://dx.doi.org/10.36076/ppj.2009/12/e277.

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Background: Neuropathic pain following breast cancer surgery can have a profoundly negative impact on the physical and psychosocial functioning of patients. Radiofrequency treatment has been used as therapy for chronic pain, which also has a problem under debate of its neurodestructive nature. Although the efficacy and safety of using glucocorticoids in nerve block treatment are controversial, they have been used to treat neuropathic pain for many years and have been used to alleviate acute and continued postoperative pain. Neither radiofrequency combined with glucocorticoids nor radiofrequenc

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Paque, Kristel, Monique Elseviers, Robert Vander Stichele, et al. "Changes in medication use in a cohort of patients with advanced cancer: The international multicentre prospective European Palliative Care Cancer Symptom study." Palliative Medicine 32, no. 4 (2017): 775–85. http://dx.doi.org/10.1177/0269216317746843.

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Background: Information on medication use in the last months of life is limited. Aim: To describe which medications are prescribed and deprescribed in advanced cancer patients receiving palliative care in relation to time before death and to explore associations with demographic variables. Design: Prospective study, using case report forms for monthly data collection. Medication included cancer treatment and 19 therapeutic groups, grouped into four categories for: (1) cancer therapy, (2) specific cancer-related symptom relief, (3) other symptom relief and (4) long-term prevention. Data were an

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Sazuka, Shoichiro, and Toshiya Koitabashi. "Tapentadol is effective in the management of moderate-to-severe cancer-related pain in opioid-naïve and opioid-tolerant patients: a retrospective study." Journal of Anesthesia 34, no. 6 (2020): 834–40. http://dx.doi.org/10.1007/s00540-020-02821-8.

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Abstract Purpose Tapentadol is a dual-acting mu-opioid receptor agonist and noradrenaline reuptake inhibitor with non-inferior analgesic efficacy to oxycodone and better gastrointestinal tolerability than full mu-opioid receptor agonists. Tapentadol is approved for cancer pain in Japan; however, real-world evidence on tapentadol’s effectiveness and safety for cancer-related pain in Japan is limited. Methods This retrospective study evaluated the effectiveness, safety, and tolerability of tapentadol (by patient type—opioid-naïve and opioid-tolerant) in 84 patients with moderate-to-severe cancer

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Hung, Joseph C. "Neurolytic Transversus Abdominal Plane Block with Alcohol for Long-Term Malignancy Related Pain Control." Pain Physician 6;17, no. 6;12 (2014): E755—E760. http://dx.doi.org/10.36076/ppj.2014/17/e755.

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There have been several case reports in the literature of neurolytic transversus abdominis plane (TAP) blocks being used for malignant abdominal wall pain. However, most used phenol as a neurolytic agent. We found only a single case report by Sakamoto using alcohol for TAP neurolysis. Unfortunately this patient passed away only 5 days after performance of the block. We attempt to extend upon the existing literature by describing neurolytic TAP blockade outcomes using alcohol on 3 cancer patients with metastatic disease to the abdominal wall. Two of our 3 patients had colorectal cancer invading

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Guo, Yu-ming, Yi-xue Huang, Hong-hui Shen, et al. "Efficacy of Compound Kushen Injection in Relieving Cancer-Related Pain: A Systematic Review and Meta-Analysis." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/840742.

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Despite widespread popular use of complementary and alternative medicine (CAM) therapies, a rigorous evidence based on the efficacy of compound kushen injection (CKI) for cancer-related pain is lacking. In this study, we evaluated the efficacy and safety of compound kushen injection and provided information for current or future research and clinical application. Sixteen trials were identified with a total of 1564 patients. The total pain relief rate of CKI plus chemotherapy is better than chemotherapy except for colorectal cancer. The treatment groups achieved a reduction in the incidences of

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De Cicco, Marcello, Mira Matovic, Roberto Bortolussi, et al. "Celiac Plexus Block." Anesthesiology 94, no. 4 (2001): 561–65. http://dx.doi.org/10.1097/00000542-200104000-00006.

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Background The success of the neurolytic celiac plexus block, despite different approaches and methods used, depends on adequate spread of the injectate in the celiac area. This retrospective study was conducted to evaluate the patterns of alcohol spread and pain relief in patients with cancer or therapy-related anatomic distortion of the celiac area. Methods From 177 cancer patients who underwent computed tomography (CT)-guided single-needle neurolytic celiac plexus block via an anterior approach, a radiologist, blind to the aim of the study, retrospectively selected 105 patients with abnorma

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Thronæs, MD, M., S. Kaasa, MD, PhD, and O. Dale, MD, PhD. "A pilot study of nasal fentanyl for patient controlled treatment of cancer pain." Journal of Opioid Management 10, no. 1 (2014): 21. http://dx.doi.org/10.5055/jom.2014.0188.

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Background: Slow release (SR) opioids around the clock are the mainstay for moderate to strong cancer pain. This recommendation is not scientifically based. Therefore, a phase 1 pilot study of rapid acting nasal fentanyl (NF) taken on demand as the only opioid for cancer pain to explore feasibility and safety aspects was launched.Methods: Patients with cancer, naïve to strong opioids but in need of such drugs, were included. They received a test dose of NF before titration (1-5 days) was started. Ten days treatment was followed by 7 days of observation after switching to SR morphine. Pain reli

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