Academic literature on the topic 'Cancer tumer'

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Journal articles on the topic "Cancer tumer"

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Battah, Arwa, Iyad Farouji, Theodore DaCosta, et al. "S2447 Tumer Lysis Syndrome - A Rare Complication of Gastric Cancer After Initiation of Keytruda." American Journal of Gastroenterology 118, no. 10S (2023): S1716. http://dx.doi.org/10.14309/01.ajg.0000959428.89405.12.

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Blaich, Günter, Hella Raade, and Manfred Metzler. "Modification of 7,8–benzoflavone metabolism in hamster liver and kidney microsomes by hepatic tumer inducing treatments." Carcinogenesis 11, no. 1 (1990): 95–101. http://dx.doi.org/10.1093/carcin/11.1.95.

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Parsons, Heather A., Timothy Blewett, Xiangying Chu, et al. "Abstract PD11-06: PD11-06 Circulating tumor DNA association with residual cancer burden after neoadjuvant therapy in triple negative breast cancer in TBCRC 030." Cancer Research 83, no. 5_Supplement (2023): PD11–06—PD11–06. http://dx.doi.org/10.1158/1538-7445.sabcs22-pd11-06.

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Abstract Background. Patients (pts) with early triple negative breast cancer (eTNBC) are at increased risk of breast cancer recurrence and death. Recent studies have focused on escalation of therapy, with current treatment standard of at least five drugs – and associated toxicities - for eTNBC. Though presence of residual disease after neoadjuvant therapy (NAT) as measured by residual cancer burden (RCB) helps guide addition of adjuvant treatment, more effective tools to tailor therapy are limited. Persistence of circulating tumor DNA (ctDNA) in the setting of residual disease is associated wi
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Curran, Paytin, DeLaney Anderson, Jeffrey Okojie, et al. "Abstract 5034: Comparative whole genome sequencing between matched cryopreserved and FFPE tumor samples." Cancer Research 85, no. 8_Supplement_1 (2025): 5034. https://doi.org/10.1158/1538-7445.am2025-5034.

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Background & Aims: Next generation sequencing, specifically whole genome sequencing (WGS), plays a key role in precision medicine. Currently, the main source of cancer biospecimens for WGS is formalin-fixed, paraffin-embedded (FFPE) tissues. This is partly because cryopreserved (CP) tissues have not been routinely stored in real-world clinical settings. This study aimed to compare the outcomes of WGS by using matched CP and FFPE samples. We hypothesized that CP samples would demonstrate superior quality metrics before and after sequencing the DNA. Methods: A total of 50 matched pairs of CP
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Cho, Bong Jun, Hans H. Kim, David J. Lee, et al. "MicroRNA-21 inhibitor potentiates anti-tumor effect of radiation therapy in vitro and in vivo." Tumor Microenvironment and Therapy 2, no. 1 (2014): 1–13. http://dx.doi.org/10.2478/tumor-2014-0001.

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AbstractMicroRNA-21 (miR-21) plays important roles in carcinogenesis and is highly expressed in diverse human cancers. We evaluated the potential of targeting miRNA-21 to overcome the radioresistance of human cancer cells having an activated EGFR2-associated signaling and also aimed to elucidate the mechanisms of radiosensitization, and the effect on epithelial- mesenchymal transition (EMT). Ectopic overexpression of miR-21 up-regulated EGFR/HER2-associated signaling and increased radioresistance of a panel of human cancer cells (U251, U87, and A549 cells). In contrast, a specific inhibitor of
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Lavekar, G. S. "Arbud-Tumor-Cancer- a concise integrative review." Journal of Clinical Oncology Reports 1, no. 1 (2023): 01–05. http://dx.doi.org/10.58489/2836-5062/001.

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The Cancerous diseases will cause 10 million deaths in 2020 and may increase in coming years (1). Since ancient times Cancer-Arbud has been considered a mega disease and critical for treatment. A review is presenting the conception, description and treatment modalities as described in ayurveda, a short review is presented in this article.
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GARCÍA CEBRIÁN, MARÍA JOSÉ, MONIKA BAUDEN, ROLAND ANDERSSON, STEFAN HOLDENRIEDER, and DANIEL ANSARI. "Paradoxical Role of HMGB1 in Pancreatic Cancer: Tumor Suppressor or Tumor Promoter?" Anticancer Research 36, no. 9 (2016): 4381–90. http://dx.doi.org/10.21873/anticanres.10981.

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Swathi, Madhavan* T. Keerthana A. Sowmiya D. Kilimozhi. "T Cell Line Treatment for Cancer Using Tumor-Infiltrating Lymphocytes." International Journal of Pharmaceutical Sciences 2, no. 11 (2024): 1653–68. https://doi.org/10.5281/zenodo.14245431.

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The understanding about tumor-infiltrating lymphocytes (TIL) plays a monumental role in the treatment of cancer, creating a hitting spot in immuno-oncology. Apart from being used as a prognostic marker for other chemotherapy, TIL places its own importance in the treatment as well. TIL therapy uses autologous tumor-infiltrating lymphocytes extracted from the tumor following the expansion in an in vitro manner. After completing lymphodepletion, the patient was ready to receive the TIL therapy. Herein, we concisely describe the process of preparing TIL for therapy. Later, we emphasize the role of
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Masood, Behzad, Afzaal Aleem Khan, Muhammad Usman, et al. "Institution Based Tumor Registry, Benazir Bhutto Hospital: A Four Year Data Based Analysis." Journal of Rawalpindi Medical College VOL 23 NO S-1 (2019): STUDENTS SUPPLEMENT, no. 23(S-1) (2019): 37–41. https://doi.org/10.5281/zenodo.5684784.

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Background: To retrieve all diagnosed cancer cases during the past four years (2014-2017) in Benazir Bhutto Hospital, Rawalpindi, and categorize them by organ sites affected/ topographically, to determine cancers with the highest prevalence in our part of the world. Materials & Methods: A hospital registry-based retrospective study was undertaken in the Department of Pathology of Benazir Bhutto Hospital, Rawalpindi. All diagnosed cases of cancer for the past four years that had been histologically confirmed, were retrieved. The cancer cases thus obtained were then classified topographicall
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Shalini, Das, Jahan Nushrat, and Mal Chittabrata. "In-silico Identification of lncRNA Functionality in Cancers Related to Obesity." International Journal of BioSciences and Technology (IJBST) ISSN: 0974-3987 13, no. 3 (2020): 34–41. https://doi.org/10.5281/zenodo.4275605.

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<strong><em>In-silico</em> Identification of lncRNA Functionality in Cancers Related to Obesity</strong> Shalini Das, Nushrat Jahan and Chittabrata Mal Amity Institute of Biotechnology, Amity University Kolkata, Rajarhat, Newtown, Action Area III, North 24 PGS, 700135, INDIA shweata7@gmail.com, nushratjahan8456@gmail.com, cmal@kol.amity.edu &nbsp; <strong>ABSTRACT:</strong> Investigating the gene expression networks that regulate cancer initiation and development is crucial but remains mostly incomplete. With the innovations in RNA-sequencing technologies and computational biology, long noncod
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Dissertations / Theses on the topic "Cancer tumer"

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Lale, Shantanu Vijay. "Development of stimuli responsive polymeric nanosystems for cancer therapeutics." Thesis, IIT Delhi, 2016. http://localhost:8080/xmlui/handle/12345678/6999.

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McGinley, Susan. "Sensitizing Tumor Response to Cancer Therapy." College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 2008. http://hdl.handle.net/10150/622086.

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Hoarau, Jessica. "Halfway Between 2D Models and Animal Models : a New Multicellular 3D Spheroid Model Organized to Study Tumor-Endothelium Interactions in Ovarian Cancer." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS111.

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Le cancer de l'ovaire (CO) est la cinquième cause de décès chez les femmes qui se caractérise par son diagnostic tardif (stades FIGO III et IV) et par l’importance de ses métastases abdominales souvent observées au moment du diagnostic. Le traitement repose sur une chirurgie cytoréductive complète associée à une chimiothérapie. Malheureusement, parmi les patientes ayant une rémission clinique complète après la fin du traitement initial, 60% des personnes atteintes d'un cancer épithélial de l'ovaire (CEO) à un stade avancé rechuteront dans les cinq ans.L'importance de la néo-angiogenèse dans le
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Stemmer, Kerstin. "Molecular Characteristics of Kidney Cancer." [S.l. : s.n.], 2008. http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-73925.

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Bonneau, Claire. "Étude des mécanismes de récidive métastatique dans les cancers du sein luminaux de stade précoce : impact du microenvironnement tumoral Caractérisation moléculaire des cancers du sein en pratique clinique A subset of activated cancer associated fibroblasts is associated with distant relapse in early luminal breast cancers." Thesis, Sorbonne Paris Cité, 2018. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=2365&f=17162.

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Les cancers du sein de stade précoce constituent un enjeu de santé publique du fait de leur fréquence élevée (70% des nouveaux cas diagnostiqués). Parmi eux, les cancers luminaux (exprimant les récepteurs hormonaux sans surexpression de l’HER2) de stade T1N0, de moins de 2cm sans envahissement ganglionnaire, ont un pronostic spontanément favorable et font ainsi l’objet de peu d’études dédiées. Néanmoins certaines de ces patientes (5 à 10% à 10 ans) vont récidiver avec des métastases à distance et mourir. L’identification de facteurs pronostiques pour ces tumeurs et une meilleure compréhension
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Dacheux, Estelle. "Implication de la protéine onco-suppressive BRCA1 dans la régulation de la traduction." Thesis, Lyon 1, 2013. http://www.theses.fr/2013LYO10077.

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BRCA1 est l’un des deux gènes majeur de prédisposition au cancer du sein. Les multiples partenaires protéiques de BRCA1 lui confèrent de nombreuses fonctions par lesquelles elle peut assurer la surveillance de l’intégrité cellulaire. L’équipe dans laquelle j’ai mené ma thèse a identifié un nouveau partenaire protéique de BRCA1, la protéine de liaison au poly(A) des ARN messagers PABP1, et a ainsi mis en lumière l’implication de BRCA1 dans la régulation de la traduction [1]. Durant ma thèse, j’ai étudié cette nouvelle fonction de BRCA1 et essayé de comprendre si, et comment, elle pourrait contr
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Pålsson, Birger. "Tumour marker CA-50 in pancreatic cancer." Lund : Dept. of Surgery, Lund University, 1993. http://catalog.hathitrust.org/api/volumes/oclc/38154714.html.

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Muller, Laure. "Modélisation et traitement du signal de rétrodiffusion lumineuse dans les tissus vivants appliques à la détection de bas niveaux de saturation en oxygène : contribution à l'optimisation de la dosimétrie en thérapie photodynamique anticancéreuse." Vandoeuvre-les-Nancy, INPL, 1994. http://www.theses.fr/1994INPL120N.

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La thérapie photodynamique, basée sur l'affinité pour les tissus tumoraux d'un agent photosensibilisant est un traitement anticancéreux prometteur mais encore en phase de recherche. Parmi les paramètres inconnus, l'action de l'oxygène est un élément essentiel a la définition d'une dosimétrie efficace de la lumière. En effet, sa détermination permet une optimisation de l'action phototoxique ainsi que la détermination d'un seuil de réussite thérapeutique. A ces fins, le développement d'un système adapte aux mesures par voie endoscopique, seul accès au site tumoral, permettant l'évaluation de l'é
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Payne, Kyle K. "Immunotherapy of Cancer: Reprogramming Tumor/Immune Cellular Crosstalk to Improve Anti-Tumor Efficacy." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3939.

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Immunotherapy of cancer has been shown to be promising in prolonging patient survival. However, complete elimination of cancer and life-long relapse-free survival remain to be major challenge for anti-cancer therapeutics. We have previously reported that ex vivo reprogramming of tumor-sensitized immune cells by bryostatin 1/ionomycin (B/I) and the gamma-chain (γ-c) cytokines IL-2, IL-7, and IL-15 resulted in the generation of memory T cells as well as CD25+ NKT cells and CD25+ NK cells. Adoptive cellular therapy (ACT) utilizing these reprogrammed immune cells protected FVBN202 mice from tumor
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Fumagalli, Debora. "Evaluation of tumor heterogeneity in breast cancer." Doctoral thesis, Universite Libre de Bruxelles, 2016. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/229735.

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Le cancer du sein est le cancer le plus fréquent chez la femme et représente la principale cause de mortalité liée au cancer. Le décés est habituellement causé par le développement de résistance aux traitements et la propagation métastatique de la maladie. Malgré la pertinence clinique, la complexité moléculaire de la maladie et sa dynamique restent à ce jour peu connues.Depuis longtemps, l’hétérogénéité du cancer du sein a été observée au niveau histologique et du profil évolutif clinique, et ces différences ont servi de base pour la classification de la maladie. Avec le développement des tec
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Books on the topic "Cancer tumer"

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Janes-Hodder, Honna. Childhood cancer: A parent's guide to solid tumor cancers. 2nd ed. O'Reilly, 2002.

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1935-, Sell Stewart, ed. Serological cancer markers. Humana Press, 1992.

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H, Goldfarb Ronald, ed. Brain tumor invasiveness. Kluwer Academic, 1994.

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T, Garrett Carleton, and Sell Stewart 1935-, eds. Cellular cancer markers. Humana Press, 1995.

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Marry M. van den Heuvel-Eibrink, ed. Wilms Tumor. Codon Publications, 2016.

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Teicher, Beverly A. Tumor Models in Cancer Research. Humana Press, 2001. http://dx.doi.org/10.1385/1592591000.

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Pag�, Michel. Tumor Targeting in Cancer Therapy. Humana Press, 2002. http://dx.doi.org/10.1385/1592591671.

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Khleif, Samir N., ed. Tumor Immunology and Cancer Vaccines. Springer US, 2005. http://dx.doi.org/10.1007/0-387-27545-2.

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Orentas, Rimas, James W. Hodge, and Bryon D. Johnson, eds. Cancer Vaccines and Tumor Immunity. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470170113.

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Thomas-Tikhonenko, Andrei, ed. Cancer Genome and Tumor Microenvironment. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-0711-0.

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Book chapters on the topic "Cancer tumer"

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Camelo, Felipe, and Anne Le. "The Intricate Metabolism of Pancreatic Cancers." In The Heterogeneity of Cancer Metabolism. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-65768-0_5.

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AbstractCurrently, approximately 95% of pancreatic cancers are pancreatic ductal adenocarcinomas (PDAC), which are the most aggressive form and the fourth leading cause of cancer death with extremely poor prognosis [1]. Poor prognosis is primarily attributed to the late diagnosis of the disease when patients are no longer candidates for surgical resection [2]. Cancer cells are dependent on the oncogenes that allow them to proliferate limitlessly. Thus, targeting the expression of known oncogenes in pancreatic cancer has been shown to lead to more effective treatment [3]. This chapter discusses
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van Herpen, Carla M. L. "Patients with Rare Head Neck Cancers: Do They Need a Different Approach?" In Critical Issues in Head and Neck Oncology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63234-2_20.

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AbstractA cancer is considered rare when the annual cancer incidence is less than 6 per 100,000 inhabitants. In absolute numbers more than 500,000 patients per year are diagnosed with a rare cancer, and 4,300,000 rare cancer patients are prevalent in Europe. The definition is widely adopted among the different scientific international societies like ESMO and ESTRO. This means that 22% of all diagnosed cancers are rare and out of the 260 cancer types identified (www.rarecare), 223 (86%) are rare. The European Network for Rare Solid Cancers (EURACAN) uses this definition to create reference netw
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Zarisfi, Mohammadreza, Tu Nguyen, Jessie R. Nedrow, and Anne Le. "The Heterogeneity Metabolism of Renal Cell Carcinomas." In The Heterogeneity of Cancer Metabolism. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-65768-0_8.

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AbstractAccording to data from the American Cancer Society, cancer is one of the deadliest health problems globally. Annually, renal cell carcinoma (RCC) causes more than 100,000 deaths worldwide [1–4], posing an urgent need to develop effective treatments to increase patient survival outcomes. New therapies are expected to address a major factor contributing to cancer’s resistance to standard therapies: oncogenic heterogeneity. Gene expression can vary tremendously among different types of cancers, different patients of the same tumor type, and even within individual tumors; various metabolic
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Kitapli, Sait, and Ali Alkan. "Immunotherapy in Gynecologic (Ovary, Endometrium and Servics) Cancer." In Immunotherapy in Human Cancers. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359388.15.

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Immunotherapy has shown remarkable success in treating various solid malignancies, but its application in gynecologic cancers is an evolving field. This paper provides a comprehensive overview of immunotherapy’s role in managing ovarian, endometrial, and cervical cancers. It delves into the mechanisms of immune checkpoint inhibitors, focusing on the PD-1 and CTLA-4 pathways, and their impact on tumor suppression. The review highlights the challenges posed by tumor immunoediting, where cancer cells evade immune responses. It emphasizes the significance of molecular phenotyping, particularly MMR
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Isik, Omer. "Hyperthermia: Causes, Symptoms, Prevention and Treatment." In Immunotherapy in Human Cancers. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359388.16.

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Hyperthermia is a type of cancer treatment in which body tissue is exposed to high temperatures to damage and kill cancer cells. The objective of this treatment is to raise the temperature in tumor up to such a therapeutic level that cell death occurs. Hyperthermia, the use of elevated temperatures to treat cancer, has emerged as a promising adjuvant therapy. By raising the temperature of tumor tissues to 40-45°C, hyperthermia enhances the effectiveness of radiation and chemotherapy. This therapeutic approach can damage and kill cancer cells with minimal harm to normal tissues, primarily by ca
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Ayag, Hatice, Sehmus Ertop, Muzeyyen Aslaner Ak, and Birsen Sahip Yesiralioglu. "Immunotherapy in Hematological Malignancy." In Immunotherapy in Human Cancers. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359388.4.

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Tumor immune tolerance represents a significant obstacle to effective cancer therapy. A multitude of pathways through which tumors evade immune surveillance have been identified . These developments have prompted a reevaluation of the "hallmarks of cancer" and have spurred the development of numerous promising immunotherapies. Various categories of immunotherapies, including stem cell transplantation, immune checkpoint inhibitors, antigen-targeted antibodies, antibody-drug conjugates, tumor vaccines, and adoptive cell therapies, have been devised for treating hematologic cancers, with ongoing
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Kapu, Venkatesh, Vanita Noronha, Nandini Menon, Minit Shah, Shripad Banavali, and Kumar Prabhash. "Metronomic Chemotherapy and Low-Dose Immunotherapy: An Intriguing Story." In Critical Issues in Head and Neck Oncology. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-84539-0_23.

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Abstract Current treatment protocols are not curative for some cancers, despite significant advancements in cancer research. To enhance the treatment of cancer, it is therefore crucial to investigate novel therapeutic targets and approaches. Metronomic chemotherapy (MCT) is novel and effective treatment approach for solid tumors and blood malignancies which entails the continuous administration of low-dose cytotoxic medications in contrast to conventional chemotherapy regimens. The main characteristics of MCT are: frequent, uninterrupted, dose-dense chemotherapy administration; use of a biolog
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Yildiz, Mehmet Siddik. "Interventional Radiological Pain Management Techniques for Cancer Patients." In The Radiology of Cancer. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359364.38.

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This chapter examines Interventional radiology techniques used in managing cancer-related pain, which affects over 10 million patients annually worldwide. Desp!te advancements in treatment, pain prevalence remains high, reaching 54.6% in advanced cancer cases. The World Health Organization’s (WHO) updated analgesic ladder provides a structured approach to pain management, incorporating interventional methods.Sympathetic blocks and neurolysis are used for persistent visceral cancer pain, employing local anesthetics or chemical agents to disrupt pain signals. The celiac ganglion block is effecti
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Ferrari, Marco, Nausica Montalto, and Piero Nicolai. "Novel Approaches in Surgical Management: How to Assess Surgical Margins." In Critical Issues in Head and Neck Oncology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63234-2_7.

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AbstractThe concept of surgical margins was born a long time ago but still lacks a univocal and sound understanding. The current biological rationale behind the recommendations on margins management relies on two pillars: (1) the observation that groups of cancer cells can leave the macroscopic tumor and disseminate throughout adjacent tissues with different degrees of aggressiveness; (2) the belief that removal of all (or most of) cancer cells can cure the patient. However, this background is undermined by some pieces of evidence. For instance, it has been proven that tissues surrounding canc
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Watson, Geoffrey Alan, Kirsty Taylor, and Lillian L. Siu. "Innovation and Advances in Precision Medicine in Head and Neck Cancer." In Critical Issues in Head and Neck Oncology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63234-2_24.

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AbstractThe clinical utility of precision medicine through molecular characterization of tumors has been demonstrated in some malignancies, especially in cases where oncogenic driver alterations are identified. Next generation sequencing data from thousands of patients with head and neck cancers have provided vast amounts of information about the genomic landscape of this disease. Thus far, only a limited number of genomic alterations have been druggable, such as NTRK gene rearrangements in salivary gland cancers (mainly mammary analogue secretory carcinoma), NOTCH mutations in adenoid cystic
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Conference papers on the topic "Cancer tumer"

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Langley, Andrew, Allison Sweeney, Christopher Nguyen, Skye Edwards, Deeksha Sankepalle, and Srivalleesha Mallidi. "Non-invasive simultaneous assessment of therapy-induced tumor microenvironmental changes in collagen and vasculature with photoacoustic imaging." In Optical Molecular Probes, Imaging and Drug Delivery. Optica Publishing Group, 2025. https://doi.org/10.1364/omp.2025.om5e.2.

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The tumor microenvironment (TME) is critical for tumor cell survival and metastasis, comprising both cellular (immune and stromal cells) and non-cellular (extracellular matrix, ECM) components. Collagen within the ECM, produced by cancer-associated fibroblasts, fosters aggressive tumor phenotypes and confers resistance to chemotherapy. To enhance the efficacy of cancer therapies, various innovative strategies are being developed to normalize or target tumor collagen. We have previously demonstrated that photodynamic therapy (PDT) at low doses, termed photodynamic priming (PDP), can degrade col
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Mekha, Sarah, Enakshi Sunassee, Miguel Salgado, et al. "Multi-probe Metabolic Fluorescence Microscopy Captures Poor Tumor Immunogenicity." In Optical Molecular Probes, Imaging and Drug Delivery. Optica Publishing Group, 2025. https://doi.org/10.1364/omp.2025.om1e.3.

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Visualizing complex tumor-immune metabolic interactions is imperative to understanding cancer progression. Cocultures of 4T1 tumor cells and CD8+ T cells were imaged for glucose uptake and mitochondrial metabolism. Results point to poor immunogenic tumor phenotype.
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Shin, Yoo-kyoung, You-rim Park, and Joo Beom Eom. "An implemented fluorescence imaging system for real-time monitoring of colorectal cancer location." In 3D Image Acquisition and Display: Technology, Perception and Applications. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/3d.2024.jf2a.10.

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We report a method for real-time monitoring of colorectal cancer, lymph node metastasis, and tumor growth inhibition of colorectal cancer cells through photodynamic therapy (PDT) using a near-infrared fluorescence diagnostic therapeutic system and fucoidan-based therapeutics. In vitro and in vivo experiments were performed to confirm the effectiveness of the manufactured system and the developed CFN-gel, which has good accumulation efficiency in cancer cells. For comparison of the fabricated CFN-gels, commercial chlorine e6 (Ce6) and 5-aminolevulinic acid (5-ALA) were used. The effectiveness o
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Sztejnberg, Manuel L., and Tatjana Jevremovic. "Advanced Application of BNCT in Advanced Cancers." In 17th International Conference on Nuclear Engineering. ASMEDC, 2009. http://dx.doi.org/10.1115/icone17-75906.

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We present a new concept of one form of radiation binary targeted therapy that may offer hope for the often fatal relapsed and/or metastasized HER2+ cancers. The idea is to deliver boronated (boron-10 isotope) anti-HER2 monoclonal antibodies (mAbs) to the patient to be deposited preferentially into the tumor followed by one session of a low energy neutron irradiation. Based on actual computed tomography data, we present the comprehensive theoretical (numerical) modeling of the new approach in designing the treatment conditions for the boron neutron capture therapy (BNCT) using the MITRII-FCB n
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Stokol, Tracy, Mandy B. Esch, Nozomi Nishimura, et al. "Little Channels, Big Disease: Using Microfluidics to Investigate Cancer Metastasis." In ASME 2011 9th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2011. http://dx.doi.org/10.1115/icnmm2011-58298.

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The leading cause of death in human patients with malignant cancer is the dissemination of the primary tumor to secondary sites throughout the body. It is well known that cancers metastasize to certain tissues (e.g. breast cancer typically spreads to the lungs. brain and bone), in a pattern that cannot be explained by blood flow from the primary tumor or simple mechanical arrest. Circulating tumor cells usually arrest in the microvasculature of target tissues. At these sites, they must adhere to the endothelium, survive, proliferate and extravasate in order to form a secondary tumor. In vitro
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Gu, Qiangqiang, Naresh Prodduturi, and Steven N. Hart. "Deep Learning in Automating Breast Cancer Diagnosis from Microscopy Images." In 2024 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2024. http://dx.doi.org/10.1115/dmd2024-1017.

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Abstract Breast cancer is one of the most common cancers in women. With early diagnosis, some breast cancers are highly curable. Classifying normal versus tumor breast tissues from microscopy images is an ideal case to use for deep learning and could help diagnose breast cancer with higher reproducibility. Since data preprocessing and hyperparameter tuning have impacts on breast cancer classification accuracies, training a classifier with appropriate data preprocessing and optimized hyperparameters could improve breast cancer classification accuracy. Using 12 combinations of model architecture
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Soucy, P., W. Ehringer, C. Klinge, H. Frieboes, and A. Gobin. "An Innovative Approach for Curcumin Delivery for Breast Cancer Using Albumin Nanoparticles." In ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/nemb2013-93295.

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Triple-negative breast cancer (TNBC) accounts for ∼25% of breast cancer among premenopausal African-American and Latino women1. Curcumin (diferuloylmethane; CCM), a natural polyphenol extracted from turmeric, has chemopreventive and chemotherapeutic activity in various cancers 2,3 and inhibits growth and invasion of TNBC/basal-like MDA-MB-231 human breast cancer cells 4. CCM has been reported to affect all stages of tumor progression and metastases due to its interactions with multiple targets. We employ a novel approach utilizing both computational and experimental modeling to characterize an
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"Brain Tumor Detection Using Deep Convolutional Neural Network." In The International Conference on scientific innovations in Science, Technology, and Management. International Journal of Advanced Trends in Engineering and Management, 2023. http://dx.doi.org/10.59544/poda4062/ngcesi23p130.

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Brain tumor is the third-most common cause of cancer related deaths in the world. Fortunately, it can be detected using MRI. Computer-aided diagnosis (CADx) systems can help clinicians identify cancer from brain diseases more accurately. In this project, propose a CAD system that distinguishes and classifies brain tumor from pre-cancerous conditions. The system uses a deplearning model. Deep CNN which involves depth wise separable convolutions, to classify cancer and non-cancers. The proposed method consist of two steps: Google’s Auto Augment for augmentation and the CV2 based feature selectio
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Lima, Beatriz Alves, Andressa da Silva Pereira, Bruna Alves Lima, et al. "PREDICTORS OF BREAST CANCER PROGNOSIS BASED ON TUMOR BIOMARKERS." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2022.

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Objective: To analyze the tumor biological markers of breast cancer associated with the prognostic of the disease. Methodology: A systematic review was carried out on the Scielo, PubMed, and the National Cancer Institute databases on the topic. Descriptors used were: tumor biomarkers, breast cancer, and prognosis. Thus, 15 articles published between 2001 and 2020 were selected. Results: Breast cancer, characterized by the disordered multiplication of breast cells, is the most incident in women in the world, representing 24.2% of the total cases in 2018, and the most frequent cause of death in
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Andrade, Gustavo Moreira, Leonardo Chaves de Oliveira Moraes, Diogo Casagrande Nunes de Souza, Isadora de Sousa Gomes, Marcos Vinícius Milki, and Izabela Ramos Nascimento. "Angiogenesis, heroine, or villain? The expression and significance of vascular endothelial growth factor when dealing with the prognosis of patients with breast cancer." In Brazilian Breast Cancer Symposium 2024. Mastology, 2024. http://dx.doi.org/10.29289/259453942024v34s1086.

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Objective: Vascular endothelial growth factor (VEGF) is an important signaling protein that acts in muscle and tissue regeneration and promotes angiogenesis. However, it can help spread the tumor through metastases. Therefore, the objective of this review was to evaluate the expression and significance of VEGF when dealing with the prognosis of patients with breast cancer. Methodology: We comprehensively searched the PubMed database for studies and trials that included expression of VEGF and breast cancer prognosis in their papers. Our systematic review followed the PRISMA statement guidelines
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Reports on the topic "Cancer tumer"

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Wang, Ying yuan, Zechang Chen, Luxin Zhang, et al. A systematic review and network meta-analysis: Role of SNPs in predicting breast carcinoma risk. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.2.0092.

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Review question / Objective: P: Breast cancer patient; I: Single nucleotide polymorphisms associated with breast cancer risk; C: Healthy person; O: By comparing the proportion of SNP mutations in the tumor group and the control group, the effect of BREAST cancer risk-related SNP was investigated; S: Case-control study. Condition being studied: Breast cancer (BC) is one of the most common cancers among women, and its morbidity and mortality have continued to increase worldwide in recent years, reflecting the strong invasiveness and metastasis characteristics of this cancer. BC is a complex dise
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Deng, Chun, Zhenyu Zhang, Zhi Guo, et al. Assessment of intraoperative use of indocyanine green fluorescence imaging on the number of lymph node dissection during minimally invasive gastrectomy: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.11.0062.

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Review question / Objective: Whether is indocyanine green fluorescence imaging-guided lymphadenectomy feasible to improve the number of lymph node dissections during radical gastrectomy in patients with gastric cancer undergoing curative resection? Condition being studied: Gastric cancer was the sixth most common malignant tumor and the fourth leading cause of cancer-related death in the world. Radical lymphadenectomy was a standard procedure in radical gastrectomy for gastric cancer. The retrieval of more lymph nodes was beneficial for improving the accuracy of tumor staging and the long-term
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Kengsakul, Malika, Gatske Nieuwenhuyzen – de Boer, and Heleen van Beekhuizen. Radiological factors associated with residual disease after cytoreductive surgery for advanced ovarian cancer. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.1.0059.

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Review question / Objective: Which radiological factors associated with incomplete cytoreduction (gross residual disease) after cytoreductive surgery (CRS) for advanced ovarian cancer? Condition being studied: Findings of CT scan and discussion in the multidisciplinary tumor board meeting (MDO) are crucial to determine the therapeutic strategy for individual ovarian cancer patients. Preferably, patients undergo primary cytoreductive surgery (CRS) followed by adjuvant chemotherapy. However, when complete cytoreduction is not considered feasible, neoadjuvant chemotherapy followed by interval cyt
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Li, Zhenqi, Guangfu Zhang, Jia Liu, and Xiaolin Li. Risk factors for gallbladder Cancer:A meta-analysis based on nearly a decade of research. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0065.

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Review question / Objective: Gallbladder cancer is a rare tumor that is mostly advanced once detected. The efficacy of surgical treatment is still controversial. Therefore, primary prevention of gallbladder cancer is important. There are many studies on risk factors for gallbladder cancer, but at present it is difficult to identify independent risk factors for gallbladder cancer, except for a history of symptomatic chronic cholecystitis and malignant transformation of a single polyp. Laparoscopic cholecystectomy is popular worldwide and can be a preventive procedure for gallbladder cancer in a
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Shyam, E., and P. Reddy. Tumor Suppressors and Breast Cancer. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada403397.

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Shyam, E., and P. Reddy. Tumor Suppressors and Breast Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada412779.

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Lin, Yawei, Yi Chen, Rongrong Liu, and Baohua Cao. Effect of exercise on rehabilitation of breast cancer surgery patients: A systematic review and meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.10.0065.

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Review question / Objective: Exercise after breast cancer surgery has proved beneficial to rehabilitation. We evaluate the best exercise for different post-surgery complications. Information sources: China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, VIP China Science and Technology Journal Database, China Biology Medicine, EMBASE and PubMed databases were searched. Combinations of breast cancer (“breast tumor”,“breast carcinoma”,“mammary carcinoma”,“breast neoplasm”) and rehabilitation exercise (“exercise”,“physical therapy”) were employed when screening abstrac
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Uribe Ruíz, Natalia Andrea, and Roberto Benavides Arenas. Enfoque del paciente con cáncer primario de origen desconocido. Facultad de Medicina Universidad de Antioquia, 2023. http://dx.doi.org/10.59473/medudea.pc.2023.17.

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El cáncer de primario de origen desconocido (en inglés, cancer of unknown primary, CUP) se define como la confirmación histológica de una metástasis para la cual el sitio anatómico del tumor que le dio origen no puede ser identificado luego de una evaluación inicial exhaustiva y racional que incluye: una historia clínica y examen físico completos, paraclínicos básicos e imágenes, entre ellas, tomografía computarizada de tórax, abdomen y pelvis.
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ZHAO, JIE, LIANHUA YE, WEI WANG, YANTAO YANG, ZHENGHAI SHEN, and SUNYIN RAO. Surgical Prognostic Factors of Second Primary Lung Cancer: A Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0047.

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Review question / Objective: The objective of this study was to explore the effects of different surgical strategies and potential prognostic factors on the prognosis of patients with SPLC through a systematic review and meta-analysis.Prognostic factors included surgical approach, type of SPLC(Synchronous and metachronous),histology,disease-free interval (DFI),tumor size,CT morphology, lymph node metastasis status, smoking status, gender. Condition being studied: With the development of imaging technology and better survival after primary lung cancer, the detection rate of second primary lung
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Suriyaphol, Gunnaporn. Study the gene expression of E-cadherin, syndecan1, matrix metalloproteinases-2, -7, -9, -14 and tissue inhibitors of metalloproteinases-1 and -2 in canine oral melanoma. Chulalongkorn University, 2015. https://doi.org/10.58837/chula.res.2015.80.

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The objectives of this study were to 1.) select the suitable reference genes for quantitative real-time polymerse chain reaction in the most common canine oral cancers: oral melanoma (OM) and oral squamous cell carcinoma (OSCC), 2.) study the gene expression of E-cadherin (CDH1), syndecan 1 (SDC1), matrix metalloproteinases-2, -7, -9, -14 (MMP2, MMP7, MMP9, MMP14) and tissue inhibitors of metalloproteinases-1 and -2 (TIMP1, TIMP2) in canine OM at the mRNA level and study the CDH1, SDC1 and Ki-67 protein expression by immunohistochemistry, and 3.) study the association of gene expression and th
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