Academic literature on the topic 'Candida, Candidiasis, superficial mycoses'

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Journal articles on the topic "Candida, Candidiasis, superficial mycoses"

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Salazar, Sara B., Rita S. Simões, Nuno A. Pedro, Maria Joana Pinheiro, Maria Fernanda N. N. Carvalho, and Nuno P. Mira. "An Overview on Conventional and Non-Conventional Therapeutic Approaches for the Treatment of Candidiasis and Underlying Resistance Mechanisms in Clinical Strains." Journal of Fungi 6, no. 1 (February 10, 2020): 23. http://dx.doi.org/10.3390/jof6010023.

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Fungal infections and, in particular, those caused by species of the Candida genus, are growing at an alarming rate and have high associated rates of mortality and morbidity. These infections, generally referred as candidiasis, range from common superficial rushes caused by an overgrowth of the yeasts in mucosal surfaces to life-threatening disseminated mycoses. The success of currently used antifungal drugs to treat candidiasis is being endangered by the continuous emergence of resistant strains, specially among non-albicans Candida species. In this review article, the mechanisms of action of currently used antifungals, with emphasis on the mechanisms of resistance reported in clinical isolates, are reviewed. Novel approaches being taken to successfully inhibit growth of pathogenic Candida species, in particular those based on the exploration of natural or synthetic chemicals or on the activity of live probiotics, are also reviewed. It is expected that these novel approaches, either used alone or in combination with traditional antifungals, may contribute to foster the identification of novel anti-Candida therapies.
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Lortholary, O., and B. Dupont. "Antifungal prophylaxis during neutropenia and immunodeficiency." Clinical Microbiology Reviews 10, no. 3 (July 1997): 477–504. http://dx.doi.org/10.1128/cmr.10.3.477.

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Fungal infections represent a major source of morbidity and mortality in patients with almost all types of immunodeficiencies. These infections may be nosocomial (aspergillosis) or community acquired (cryptococcosis), or both (candidiasis). Endemic mycoses such as histoplasmosis, coccidioidomycosis, and penicilliosis may infect many immunocompromised hosts in some geographic areas and thereby create major public health problems. With the wide availability of oral azoles, antifungal prophylactic strategies have been extensively developed. However, only a few well-designed studies involving strict criteria have been performed, mostly in patients with hematological malignancies or AIDS. In these situations, the best dose and duration of administration of the antifungal drug often remain to be determined. In high-risk neutropenic or bone marrow transplant patients, fluconazole is effective for the prevention of superficial and/or systemic candidal infections but is not always able to prolong overall survival and potentially selects less susceptible or resistant Candida spp. Primary prophylaxis against aspergillosis remains investigative. At present, no standard general recommendation for primary antifungal prophylaxis can be proposed for AIDS patients or transplant recipients. However, for persistently immunocompromised patients who previously experienced a noncandidal systemic fungal infection, prolonged suppressive antifungal therapy is often indicated to prevent a relapse. Better strategies for controlling immune deficiencies should also help to avoid some potentially life-threatening deep mycoses. When prescribing antifungal prophylaxis, physicians should be aware of the potential emergence of resistant strains, drug-drug interactions, and the cost. Well-designed, randomized, multicenter clinical trials in high-risk immunocompromised hosts are urgently needed to better define how to prevent severe invasive mycoses.
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Nehmatulla, Vian B. "Isolation and Identification of Candida Species and Some Superficial Mycosis Associated with Diaper Dermatitis in Erbil City." Polytechnic Journal 11, no. 1 (June 30, 2021): 98–103. http://dx.doi.org/10.25156/ptj.v11n1y2021.pp98-103.

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Diaper dermatitis (DD) is the most common cutaneous diagnosis in infancy that affects almost every child during the early months of their life time; most cases are associated with the yeast colonization of Candida or DD candidiasis and some dermatophytes. It is an irritating and inflammatory acute dermatitis in the perineal and perianal areas resulting from the occlusion and irritation caused by diapers. The study aimed to assess the association between Candida species and some dermatophytes in infants with napkin dermatitis and determine the prevalence of DD in relation with yeast (Candida) colonization and identify common Candida spp. which is responsible for Candida (fungal) DD among infants. Data from 210 infants aged between (0 and 18) months are collected from January to August 2018 in Raparin Hospital in Erbil City. The cases include 113 (53.80%) male infants and 97 (46.19%) female infants and diagnosed with DD. Results of 210 infant with diaper rash participated in this study. 188 (89.52%) were positive for Candida spp. and Dermatophytes (molds). From the total yeast number, Candida albicans was the most predominant species accounting 128 (84.21%), while 24 (15.78%) were non-albicans and dermatophyte molds among which Malassezias spp that accounted 26 (13.83%) and 10 (5.32%), respectively. The percentage of misdiagnosed cases was 9 (4.28%). Infants at age group 6–12 months showed high frequency with diaper rash 127 (60.47%). The prevalence of DD is higher in urban 120 (57.14%) than rural area 90 (42.85%). Furthermore, high prevalence DD found in hot season than colds was 121 (64.36%) and 67 (35.63%), respectively. In conclusion, I found that there are high association between DD with Candida spp. and dermatophytes and Candida albicans is a common invader of all types of napkin eruption.
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Dias, Maria Fernanda Reis Gavazzoni, Fred Bernardes-Filho, Maria Victória Pinto Quaresma-Santos, Adriana Gutstein da Fonseca Amorim, Regina Casz Schechtman, and David Rubem Azulay. "Treatment of superficial mycoses: review - part II." Anais Brasileiros de Dermatologia 88, no. 6 (December 2013): 937–44. http://dx.doi.org/10.1590/abd1806-4841.20132018.

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Superficial fungal infections of the hair, skin and nails are a major cause of morbidity in the world. Choosing the right treatment is not always simple because of the possibility of drug interactions and side effects. The first part of the article discusses the main treatments for superficial mycoses - keratophytoses, dermatophytosis, candidiasis, with a practical approach to the most commonly-used topical and systemic drugs , referring also to their dosage and duration of use. Promising new, antifungal therapeutic alternatives are also highlighted, as well as available options on the Brazilian and world markets.
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Sokolova, T. V., and A. P. Malyarchuk. "Candidiasis balanoposthitis as an important problem of superficial skin mycoses." Klinicheskaya dermatologiya i venerologiya 16, no. 2 (2017): 33. http://dx.doi.org/10.17116/klinderma201716233-43.

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Otasevic, Suzana, Jovana Đorđević, Gordana Ranđelović, Aleksandra Ignjatović, Predrag Stojanović, Dragan Zdravković, and Roberta Marković. "Superficial mycoses in the Nis region, Southeast-Serbia." Open Medicine 6, no. 5 (October 1, 2011): 665–71. http://dx.doi.org/10.2478/s11536-011-0052-y.

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AbstractThe aim of the study is to investigate the most frequent cause of superficial mycoses in patients from the territory of city Niš Southeast Serbia in the period from 1998 to 2010. A total of 3223 samples from 2887 patients with suspected dermatomycoses were examined. Superficial mycoses were diagnosed using standard microbiology techniques (conventional microscopy and cultivation). Dermatophytes were determined on the basis of their macroscopic and microscopic morphological and morphometric characteristics. Morphometric characteristics were obtained by Laboratory Universal Computer Image Analysis system (Lucia M, 1996). Species of genus Candida were identified using the test of production of germ tube in sera, by growth on comertial chromatogen medium (Chromotogenic Candida, Liofichem/Bacteriology products, Italy) and by using Auxacolor TMBioRad, France. The results were elaborated with the statistical method of descriptive and quantitative analysis (SPSS 14.0 for Windows 2003). The prevalence of superficial mycoses was 25,1%. Dermatophytes were identified in 67.6% of all positive cultures. Microsporum canis was the most prevalent (50.3%) dermatophyte isolated, followed by Trichophyton metagrophytes var. mentagrophytes (35.4%). Yeast genus Candida has become a more frequent cause of superficial fungal infection since 2001. and C. albicans was the dominant yeast (61.1%).
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Kornisheva, V. G., and E. V. Zueva. "SENSITISATION TO CANDIDA ALBICANS IN PATIENTS WITH SUPERFICIAL MYCOSES." Mycoses 45, S2 (August 2002): 32. http://dx.doi.org/10.1111/j.1439-0507.2002.tb04643.x.

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Shurygin, A. A., A. E. Shirinkina, E. A. Makarova, A. V. Sergeev, and I. A. Marusich. "Clinical case of invasive candidiasis in phthisiatrician’s practice." Perm Medical Journal 36, no. 6 (January 30, 2020): 83–94. http://dx.doi.org/10.17816/pmj36683-94.

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The paper presents a case of generalized candidomycosis in a 67-year old woman. Literature data regarding the cases of respiratory mycoses and candida sepsis are summarized. This case is interesting from the point of view of difficulty of differential diagnosis in patients with respiratory mycosis and tuberculosis, choice of adequate treatment.
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Ahmedova, S. D. "Analysis of the incidence of dermatomycosis in Azerbaijani Republic during 2000-2016." Kazan medical journal 99, no. 2 (April 15, 2018): 296–300. http://dx.doi.org/10.17816/kmj2018-296.

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Aim. To conduct epidemiological analysis of the incidence of dermatomycosis (superficial mycoses of skin and its appendages) in the Republic of Azerbaijan during 2000-2016, as well as clinical epidemiological monitoring during 2011-2016. Methods. Analysis of incidence of visits was performed in the Republican dermato-venerologic clinic, children's republican dermato-venerologic dispansary №3, city dermato-venerologic dispansary №1 of the Republic of Azerbaijan according to the forms of state statistical observation №9 («Information about predominantly sexually transmitted diseases, fungal skin infections and scabies») approved by the decree of Azerbaijan State Statistical Commission No. 72/5 issued on 04.12.2000. Clinical analysis of dermatomycosis incidence during 2011-2016 was performed based on the results of laboratory (microscopic) verification of mycelium of the fungus. Results. During 2000-2016 in the Republic of Azerbaijan steady increase of the incidence of superficial mycoses of skin and its appendages was observed. In 2000 the incidence was 2783. In 2016, 12 630 cases were recorded, which is the peak value and is 4.5 times higher than in 2000. Clinical analysis of incidence of superficial mycoses of skin and its appendages in 2011-2016 demonstrated that the diagnosis of pityriasis versicolor (keratomycosis) took the leading place (33.5%). The second place in the prevalence was taken by smooth skin mycoses (32.7%), the third place - by candidiasis (skin and visible mucous membranes - 17.1%), the fourth place - by onychomycosis (14.5%), and the last place - by mycosis of the scalp and face (2.2%). Young population (10-20 years) is susceptible to keratomycosis, and adult population (30-50 years) - to smooth skin mycosis. We suggest that it is related to climate-geographic features, increased insolation, and as a result - to sweating and to disordered lipid-alkaline protective skin barrier. To confirm our hypothesis further investigation is necessary. Conclusion. Incidence of superficial mycoses of skin and its appendages, increased by 4.5 times was revealed; the leading position in prevalence is taken by pityriasis versicolor, the second - by smooth skin mycoses and the third - by skin and visible mucous membranes candidiasis.
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Akhmedova, S. D. "Retrospective analysis of the superficial dermatomycosis prevalence in areas of the Greater Caucasus of Azerbaijan." Kazan medical journal 96, no. 6 (December 15, 2015): 1038–42. http://dx.doi.org/10.17750/kmj2015-1038.

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Aim. Study the epidemiological situation regarding the prevalence of skin, hair or nails superficial mycoses in 15 districts of the Greater Caucasus of Azerbaijan for the period from 2000 to 2012. Methods. Such indicators as the number of patient visits, periodic screening examinations and admissions were analyzed using the current and archived medical records of the Municipal Center for Skin and Sexually transmitted diseases №1, Republican Center for Skin and Sexually transmitted diseases, Republican Paediatric Center for Skin and Sexually transmitted diseases №3 of the Azerbaijan Republic. Skin superficial mycoses were diagnosed after laboratory (microscopic) verification of fungal mycelium presence. Intensive indicators were calculated, such as the prevalence of skin superficial mycoses and the number of patient visits due to skin superficial mycoses. Results. The prevalence of the skin superficial mycoses has increased in the Greater Caucasus of Azerbaijan area at the examined period (2000 to 2012) since 2004, with the prevalence peaks in 2007, 2009 and 2011. Men were twice (61.54%) more commonly affected compared to women (38.06%). The highest prevalence of skin superficial mycoses was registered in age groups of 0-10 (38.69%) and 11-20 (20.83%) years, the main diagnosis were «scalp mycosis» (27.98%) and «tinea versicolor» (22.62%). The prevalence of skin candidiasis (1.19±0.84%), onychomycosis (4.17±1.54%), tinea cruris (5.36±1.74%), combined scalp and glabrous skin mycosis (5.95±1.83%), athlete’s foot (8.93±2.20%), «Kerion» lesions (10.71±2.39%), glabrous skin mycosis (13.10±2.60%) increased. The prevalence of skin superficial mycoses was the highest in 2011 - 1.980±0.388%, the number of patient visits due to skin superficial mycoses - 0.712±0.140%; in 2007 the following numbers were 1.911±0.390% and 0.607±0.124% respectively, in 2009 - 1.637±0.357% and 0.537±0.117%, duplicating the prevalence peaks. High prevalence of superficial dermatomycoses was seen in Khizi and Ismailli Districts, the lowest - in Balakan, Qusar, Oghuz, Shaki Districts. Conclusions. In the current social and economic conditions, the system of complex examination (cultures, microscopy) of patients with skin mycoses is required, as well as the program of targeted preventive measures and improvement of medical and social aid management.
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Dissertations / Theses on the topic "Candida, Candidiasis, superficial mycoses"

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Mashao, Mmbangiseni Beauty. "Prevalence and molecular identification of candida oral infections in HIV patients attending treatment centres, Vhembe District, Limpopo Province." Diss., 2014. http://hdl.handle.net/11602/166.

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Books on the topic "Candida, Candidiasis, superficial mycoses"

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Rockwell, Sally J. Coping with Candida cook book. Seattle: Diet Design by Rockwell, 1986.

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Odds, F. C. Candida and candidosis. 2nd ed. London: Baillière Tindall, 1988.

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Candida and candidosis. 2nd ed. London: Baillière Tindall, 1988.

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Hube, Bernhard, and Oliver Kurzai. Candida species. Edited by Christopher C. Kibbler, Richard Barton, Neil A. R. Gow, Susan Howell, Donna M. MacCallum, and Rohini J. Manuel. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755388.003.0011.

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Most pathogenic Candida species are members of the microbiota, but also cause superficial or invasive infections. C. albicans is predominant, followed by C. glabrata, C. parapsilosis, and C. tropicalis. C. albicans is polymorphic and grows as yeast, pseudohyphae, or hyphae. The cell wall has multiple functions in pathogenesis. Metabolism and nutrient up-take strategies facilitate growth in multiple niches within the host. Drug resistance is an intrinsic property of C. glabrata and C. krusei, but can be developed by C. albicans and other Candida species during antifungal therapy. Pathogenicity mechanisms include host cell attachment, invasion, and destructive activities; immune evasion; and biofilm production. A disbalanced microbiota and impaired immunity favour superficial infections, and disturbance of the mucosal barriers, together with compromised immunity, enables Candida to invade the human bloodstream and cause invasive infection. Even with antifungal therapy (e.g. azoles or echinocandins), disseminated candidiasis has a high mortality (40–50%).
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Maziarz, Eileen K., and John R. Perfect. Fungal infections of the kidney and those associated with renal failure, dialysis, and renal transplantation. Edited by Christopher C. Kibbler, Richard Barton, Neil A. R. Gow, Susan Howell, Donna M. MacCallum, and Rohini J. Manuel. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755388.003.0029.

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Fungal infections involving the kidney are often a manifestation of disseminated fungal infection, although primary renal fungal infections do occur, usually from a lower urinary tract source or in the setting of renal transplantation. Candida spp. cause the vast majority of these infections and are the representative pathogen for understanding the pathogenesis of these types of infections. The risk factors and mycology of acute renal candidiasis reflect those of invasive candidiasis. Unique risk factors are observed in chronic renal candidiasis, which manifests differently and requires distinct management approaches. This chapter discusses the spectrum of invasive mycoses involving the kidney, as well as those associated with chronic renal failure, dialysis, and renal transplantation.
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J, Ernst Erika, and Rogers P. David, eds. Antifungal agents: Methods and protocols. Totowa, N.J: Humana Press, 2005.

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Ernst, Erika J. Antifungal Agents (Methods in Molecular Medicine). Humana Press, 2005.

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Lester, Rebecca, and John Rex. Fungaemia and disseminated infection. Edited by Christopher C. Kibbler, Richard Barton, Neil A. R. Gow, Susan Howell, Donna M. MacCallum, and Rohini J. Manuel. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755388.003.0025.

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Invasive fungal disease can present without localization or obvious target organ involvement. These disseminated mycoses occur predominantly in patients who are immunocompromised, particularly from haematological malignancy and HIV. Candidiasis and aspergillosis are the commonest forms of disseminated fungal infection worldwide, but an increasing number of non-Candida yeasts and non-Aspergillus moulds have emerged as important causes of invasive disease in recent years. Endemic fungi such as Histoplasma capsulatum are important causes of invasive disease within limited geographic regions. Fever is the commonest manifestation of disseminated fungal infection, but other clinical features such as cutaneous manifestations may point to a specific diagnosis. Definitive diagnosis relies on the detection of fungi in tissue or blood, but serological tests can augment diagnosis in some infections. Mortality from disseminated fungal disease is high and prompt initiation of antifungal therapy—where invasive disease is suspected—is essential.
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Book chapters on the topic "Candida, Candidiasis, superficial mycoses"

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Carpenter, Christopher F., and Nicholas Gilpin. "Candidiasis." In Schlossberg's Clinical Infectious Disease, edited by Cheston B. Cunha, 1109–16. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190888367.003.0170.

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This chapter examines Candida spp., small, unicellular yeasts that are found in a number of environments, including soil, hospital surroundings, food, and other inanimate objects. Candida may live as commensal organisms, colonizing the skin, gastrointestinal tract, and vagina; they become opportunistic pathogens when the host has compromised immunologic or mechanical defenses. Candida are common causes of disease ranging from superficial cutaneous and mucocutaneous infections to invasive infections such as candidemia and disseminated candidiasis. The chapter reviews more than 150 species of Candida, with C. albicans being the most frequently implicated in human disease processes. It traces the noticeable increase in disease due to non-albicans species over the past two decades.
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