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Journal articles on the topic 'Cannabis Delivery in Durham'

Author: Grafiati

Published: 27 July 2024

Last updated: 31 July 2025

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1

Osaghae, Ikponmwosa, Onyema Greg Chido-Amajuoyi, Banda A. A. Khalifa, Rajesh Talluri, and Sanjay Shete. "Cannabis Use among Cancer Survivors: Use Pattern, Product Type, and Timing of Use." Cancers 15, no. 24 (2023): 5822. http://dx.doi.org/10.3390/cancers15245822.

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Despite growing interest in the use of cannabis for the treatment of cancer-related symptoms, there are limited studies that have assessed the use pattern, type, and mode of delivery of cannabis products used by cancer survivors. This study describes the current state of the use pattern, product type, and mode of delivery of cannabis used by cancer survivors. This was a cross-sectional study of cancer survivors from 41 U.S. states who received treatment at the largest NCI-designated comprehensive cancer center. The weighted prevalence of the use patterns, product types, and modes of delivery o

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Murphy, Fiona, Paloma Sales, Sheigla Murphy, Sheigla Averill, Nicholas Lau, and Sye-Ok Sato. "Baby Boomers and Cannabis Delivery Systems." Journal of Drug Issues 45, no. 3 (2015): 293–313. http://dx.doi.org/10.1177/0022042615580991.

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Gill, Harkiran K., and Sean D. Young. "Exploring cannabis use reasons and experiences among mobile cannabis delivery patients." Journal of Substance Use 24, no. 1 (2018): 15–20. http://dx.doi.org/10.1080/14659891.2018.1489012.

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Ouellette, Rachel R., Sophia Selino, and Grace Kong. "Electronic Nicotine Delivery Systems and E-Liquid Modifications to Vape Cannabis Depicted in Online Videos." JAMA Network Open 6, no. 11 (2023): e2341075. http://dx.doi.org/10.1001/jamanetworkopen.2023.41075.

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ImportanceElectronic nicotine delivery systems (ENDS) were created to vape nicotine e-liquids; however, social media demonstrates increased ENDS modifications to vape cannabis. Analysis of social media content helps with understanding ENDS modifications for cannabis use, overlapping markets for ENDS and cannabis, and the need for additional regulation.ObjectiveTo analyze online videos for use, modification, and marketing of ENDS to vape cannabis.Design, Setting, and ParticipantsIn this qualitative study, 10 searches were performed on YouTube on July 14, 2022, using different combinations of re

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Pote, Siddhesh, Parul Khurana, Gaganjyot Kaur, and Sonali Kokane. "Therapeutic Potential of Cannabis Plant." INTERNATIONAL JOURNAL OF PLANT AND ENVIRONMENT 9, no. 03 (2023): 192–201. http://dx.doi.org/10.18811/ijpen.v9i03.02.

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The aim of this review article is to outline the role of the plant Cannabis sativa in treating human ailments. Giant pharmaceuticalcompanies are marketing phytochemicals extracted from Cannabis plant and its derivatives to treat epilepsy and multiple sclerosis.The present review emphasizes cannabinoids – its derivatives and synthetic analogs – as an active pharmaceutical Ingredient to treatailments related to autoimmune human body responses. The endocannabinoid system CB1 and CB2 respond differently to variousphytochemicals such as cannabidiol, tetrahydrocannabinol and terpenes. They also inte

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Young-Wolff, Kelly C., Alex Asera, Alisa A. Padon, et al. "Association of Local Cannabis Policy and Retail Availability With Cannabis Use and Problematic Cannabis Use Among Adolescents in Northern California." American Journal of Public Health 114, S8 (2024): S654—S663. http://dx.doi.org/10.2105/ajph.2024.307787.

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Objectives. To examine whether local cannabis policies and retail availability are associated with cannabis use and problematic cannabis use (PCU) among adolescents in Northern California. Methods. The sample comprised adolescents aged 13 to 17 years screened for past-year cannabis use during well-child visits in 2021. Exposures included local bans on cannabis storefront retailers, policy protectiveness, and retail proximity and density. Outcomes included self-reported past-year cannabis use and PCU diagnoses. Modified Poisson regression models adjusted for sociodemographics. Results. The samp

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Colbert, Mitchell R. "Raising the Volume: How Regulations and Consumer Market Trends Have Increased the Volume of Cannabis Packaging Waste in California." Journal of Testing and Evaluation 52, no. 6 (2024): 3253–71. https://doi.org/10.1520/jte20230806.

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Abstract The early cannabis legalization movement was linked to the environmental movement, and although legalization advocates envisioned an environmentally friendly cannabis industry, regulations and market trends complicated matters. A seismic event for cannabis waste was the repurposing of electronic nicotine delivery system (ENDS) technology as cannabis “vape pens,” which are more accurately referred to as an electronic cannabis delivery system (ECDS). With the adoption of this technology, a waste stream that had lower weight and was largely compostable shifted to become a waste stream in

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Fataar, Fathima, and David Hammond. "The Prevalence of Vaping and Smoking as Modes of Delivery for Nicotine and Cannabis among Youth in Canada, England and the United States." International Journal of Environmental Research and Public Health 16, no. 21 (2019): 4111. http://dx.doi.org/10.3390/ijerph16214111.

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Background: Vaping has become an increasingly common mode of administration for both nicotine and cannabis, with overlap among users, devices, as well as nicotine and cannabis companies. There is a need to understand patterns of use among youth, including the way nicotine and cannabis are administered. Methods: Data are from Wave 2 of the ITC Youth Tobacco and Vaping survey, an online survey conducted in 2018 among 16–19 year-olds recruited from commercial panels in Canada (n = 3757), England (n = 3819), and the U.S. (n = 3961). The prevalence of past 30-day vaping nicotine, non-nicotine and c

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Hernández-Serrano, Olga, Maria Eugènia Gras, Mariano Gacto, Alicia Brugarola, and Sílvia Font-Mayolas. "Family Climate and Intention to Use Cannabis as Predictors of Cannabis Use and Cannabis-Related Problems among Young University Students." International Journal of Environmental Research and Public Health 18, no. 17 (2021): 9308. http://dx.doi.org/10.3390/ijerph18179308.

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Determining the predictive variables associated with cannabis use and cannabis-related problems can ease the identification of young cannabis consumers who can benefit from prevention interventions. This study aimed: (1) to describe, among university students, the cannabis use and cannabis-use problems, intention to use cannabis and family climate based on the gender and the people the student lives with; (2) to explore whether the family climate and intention to use cannabis are predictors of cannabis use and cannabis-related problems. The sample was composed of 339 Spanish undergraduates (51

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Cranford, Jason A., and Donald C. Cooper. "The manufacture of filtered cannabis cigarettes: uniform particle distribution and combustion properties for consistent cannabinoid delivery." F1000Research 4 (December 17, 2015): 1466. http://dx.doi.org/10.12688/f1000research.7472.1.

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Here we describe a manufacturing process for the production of commercial filtered Cranfords cannabis cigarettes (CN). Unlike production of filtered tobacco cigarettes, standardization in the manufacture of cannabinoid containing cigarettes is lacking. The numerous cannabis strains with variable cannabinoid content, differences in cultivation methods and variability in assembly associated with hand-rolled cannabis cigarettes makes consistent cannabinoid inhalation dosing challenging. To address the growing need for standardization in the manufacture of cannabis cigarettes we developed a proces

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Gourlay, Douglas. "Addiction and Pain Medicine." Pain Research and Management 10, suppl a (2005): 38A—43A. http://dx.doi.org/10.1155/2005/512653.

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The adequate cotreatment of chronic pain and addiction disorders is a complex and challenging problem for health care professionals. There is great potential for cannabinoids in the treatment of pain; however, the increasing prevalence of recreational cannabis use has led to a considerable increase in the number of people seeking treatment for cannabis use disorders. Evidence that cannabis abuse liability is higher than previously thought suggests that individuals with a history of substance abuse may be at an increased risk after taking cannabinoids, even for medicinal purposes. Smoked cannab

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Camacho-Rivera, Marlene, Jessica Y. Islam, Diane L. Rodriguez, and Denise C. Vidot. "Cannabis Use among Cancer Survivors amid the COVID-19 Pandemic: Results from the COVID-19 Cannabis Health Study." Cancers 13, no. 14 (2021): 3495. http://dx.doi.org/10.3390/cancers13143495.

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Clinical indications for medicinal cannabis use include those with cancer, a subgroup advised to avoid exposure to COVID-19. This study aims to identify changes to cannabis use, methods of cannabis delivery, and coping strategies among cancer survivors since the pandemic by cancer status. Chi-squared tests were used for univariate comparisons of demographic characteristics, cannabis use patterns, COVID-19 symptoms, and coping behaviors by cancer survivor status. Data included 158 responses between 21 March 2020 and 23 March 2021, from medicinal cannabis users, categorized as cancer survivors (

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Sands, Mike. "The entrepreneur and the bureaucrat… or vice versa." International Journal of Entrepreneurship and Innovation 1, no. 1 (2000): 65. http://dx.doi.org/10.1177/146575030000100108.

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In Notes from the Front, practising entrepreneurs offer personal perspectives on significant issues in light of their own business experience. This issue's author, Mike Sands, is founder and Managing Director of the Durham Associates Group of companies based in the UK. He is 49 and has an MBA from Durham University Business School. Before forming Durham Associates 10 years ago, he was involved in an electronics start-up company that was successfully sold after four years. His current company generates about half of its income from design work, particularly from what is known as ‘new media’, an

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Sands, Mike. "The Entrepreneur and the Bureaucrat … or Vice Versa." International Journal of Entrepreneurship and Innovation 1, no. 1 (2000): 65. http://dx.doi.org/10.5367/000000000101298522.

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In Notes from the Front, practising entrepreneurs offer personal perspectives on significant issues in light of their own business experience. This issue's author, Mike Sands, is founder and Managing Director of the Durham Associates Group of companies based in the UK. He is 49 and has an MBA from Durham University Business School. Before forming Durham Associates 10 years ago, he was involved in an electronics start-up company that was successfully sold after four years. His current company generates about half of its income from design work, particularly from what is known as ‘new media’, an

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Ryan, Jennie E., Sean Esteban McCabe, and Carol J. Boyd. "Medicinal Cannabis: Policy, Patients, and Providers." Policy, Politics, & Nursing Practice 22, no. 2 (2021): 126–33. http://dx.doi.org/10.1177/1527154421989609.

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Medicinal cannabis is legal in some form in 47 states, 3 United States territories, and the District of Columbia. An estimated three million Americans use cannabis for relief of a variety of illnesses, and this figure is expected to grow based on policy changes. However, cannabis remains illegal at the federal level as a Schedule I drug under the 1970 Controlled Substances Act. Schedule I classification of cannabis has impeded the advancement of research, leaving providers with little evidence-based information to educate their patients. Furthermore, the disparities in individual state laws cr

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Spindle, Tory R., Edward J. Cone, Nicolas J. Schlienz, et al. "Acute Pharmacokinetic Profile of Smoked and Vaporized Cannabis in Human Blood and Oral Fluid." Journal of Analytical Toxicology 43, no. 4 (2019): 233–58. http://dx.doi.org/10.1093/jat/bky104.

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Abstract Currently, an unprecedented number of individuals can legally access cannabis. Vaporization is increasingly popular as a method to self-administer cannabis, partly due to perception of reduced harm compared with smoking. Few controlled laboratory studies of cannabis have used vaporization as a delivery method or evaluated the acute effects of cannabis among infrequent cannabis users. This study compared the concentrations of cannabinoids in whole blood and oral fluid after administration of smoked and vaporized cannabis in healthy adults who were infrequent users of cannabis. Seventee

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Kaufmann, Christopher, Kevin Yang, Atul Malhotra, Khai Nguyen, Reva Nafsu, and Alison Moore. "Use of Cannabis for Sleep: Patterns of Use Among a Sample of Patients in a Geriatrics Clinic." Innovation in Aging 4, Supplement_1 (2020): 579. http://dx.doi.org/10.1093/geroni/igaa057.1927.

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Abstract Cannabis may be useful for treatment of sleep problems in older adults. Little is known about use patterns of cannabis for sleep. We conducted a clinic-based anonymous survey in a geriatrics clinic in La Jolla, CA. Among n=568 surveys, 10% reported recent use (within past 6 months). Among recent users, 30% reported using cannabis for sleep, most finding it helpful. Compared to cannabis users for other conditions, cannabis users for sleep were more likely to use THC containing products (62.5% vs. 32.1%), use cannabis on a daily or weekly basis (76.2% vs. 43.2%), use vape pens (29.2% vs

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Hemsing, Natalie, and Lorraine Greaves. "New Challenges: Developing Gendered and Equitable Responses to Involuntary Exposures to Electronic Nicotine Delivery Systems (ENDS) and Cannabis Vaping." International Journal of Environmental Research and Public Health 15, no. 10 (2018): 2097. http://dx.doi.org/10.3390/ijerph15102097.

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Recreational cannabis use is in the process of being legalized in Canada, and new products and devices for both nicotine and cannabis vaping are being introduced. Yet, research on the harms of involuntary exposure to electronic nicotine delivery systems (ENDSs) and cannabis vaping is in its infancy, and there is a lack of investigation on sex-specific health effects and gendered patterns of exposure and use. We argue that responses to ENDS and cannabis vaping exposures should align with policy and progress on restricting exposure to tobacco secondhand smoke (SHS). Furthermore, we argue that se

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Mahmoudinoodezh, Haleh, Srinivasa Reddy Telukutla, Sukhvir Kaur Bhangu, Ava Bachari, Francesca Cavalieri, and Nitin Mantri. "The Transdermal Delivery of Therapeutic Cannabinoids." Pharmaceutics 14, no. 2 (2022): 438. http://dx.doi.org/10.3390/pharmaceutics14020438.

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Recently, several studies have indicated an increased interest in the scientific community regarding the application of Cannabis sativa plants, and their extracts, for medicinal purposes. This plant of enormous medicinal potential has been legalised in an increasing number of countries globally. Due to the recent changes in therapeutic and recreational legislation, cannabis and cannabinoids are now frequently permitted for use in clinical settings. However, with their highly lipophilic features and very low aqueous solubility, cannabinoids are prone to degradation, specifically in solution, as

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Stasiłowicz-Krzemień, Anna, Wiktoria Nogalska, Zofia Maszewska, et al. "The Use of Compounds Derived from Cannabis sativa in the Treatment of Epilepsy, Painful Conditions, and Neuropsychiatric and Neurodegenerative Disorders." International Journal of Molecular Sciences 25, no. 11 (2024): 5749. http://dx.doi.org/10.3390/ijms25115749.

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Neurological disorders present a wide range of symptoms and challenges in diagnosis and treatment. Cannabis sativa, with its diverse chemical composition, offers potential therapeutic benefits due to its anticonvulsive, analgesic, anti-inflammatory, and neuroprotective properties. Beyond cannabinoids, cannabis contains terpenes and polyphenols, which synergistically enhance its pharmacological effects. Various administration routes, including vaporization, oral ingestion, sublingual, and rectal, provide flexibility in treatment delivery. This review shows the therapeutic efficacy of cannabis i

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Schluter, Magdalen G., and David C. Hodgins. "Measuring recent cannabis use across modes of delivery: Development and validation of the Cannabis Engagement Assessment." Addictive Behaviors Reports 15 (June 2022): 100413. http://dx.doi.org/10.1016/j.abrep.2022.100413.

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Mathre, Mary. "Cannabis series — the whole story Part 5: Research and development of Cannabis preparations and delivery systems." Drugs and Alcohol Today 2, no. 4 (2002): 4–8. http://dx.doi.org/10.1108/17459265200200027.

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Crosland, B. Adam, Bharti Garg, Gretchen E. Bandoli, et al. "Risk of Adverse Neonatal Outcomes After Combined Prenatal Cannabis and Nicotine Exposure." JAMA Network Open 7, no. 5 (2024): e2410151. http://dx.doi.org/10.1001/jamanetworkopen.2024.10151.

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ImportanceThe prevalence of cannabis use in pregnancy is rising and is associated with adverse perinatal outcomes. In parallel, combined prenatal use of cannabis and nicotine is also increasing, but little is known about the combined impact of both substances on pregnancy and offspring outcomes compared with each substance alone.ObjectiveTo assess the perinatal outcomes associated with combined cannabis and nicotine exposure compared with each substance alone during pregnancy.Design, Setting, and ParticipantsThis retrospective population-based cohort study included linked hospital discharge da

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Kitdumrongthum, Sarunya, and Dunyaporn Trachootham. "An Individuality of Response to Cannabinoids: Challenges in Safety and Efficacy of Cannabis Products." Molecules 28, no. 6 (2023): 2791. http://dx.doi.org/10.3390/molecules28062791.

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Since legalization, cannabis/marijuana has been gaining considerable attention as a functional ingredient in food. ∆-9 tetrahydrocannabinol (THC), cannabidiol (CBD), and other cannabinoids are key bioactive compounds with health benefits. The oral consumption of cannabis transports much less hazardous chemicals than smoking. Nevertheless, the response to cannabis is biphasically dose-dependent (hormesis; a low-dose stimulation and a high-dose inhibition) with wide individuality in responses. Thus, the exact same dose and preparation of cannabis may be beneficial for some but toxic to others. T

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Saran, Savreen K., Kalin Z. Salinas, Jonathan Foulds, et al. "A Comparison of Vaping Behavior, Perceptions, and Dependence among Individuals Who Vape Nicotine, Cannabis, or Both." International Journal of Environmental Research and Public Health 19, no. 16 (2022): 10392. http://dx.doi.org/10.3390/ijerph191610392.

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Background: Electronic delivery systems (e.g., vapes, e-cigarettes) are now popular modes of cannabis and nicotine administration that are often used by the same individuals; however, we still know little about dual nicotine and cannabis vaping. Materials & Methods: An online convenience sample of adult nicotine and/or cannabis vape users residing in the United States completed a 60 min survey on sociodemographic characteristics, cannabis and/or nicotine vape use behaviors and dependence, reasons for vape use, and perceptions of benefits and harms. After data cleaning, we compared dual vs.

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Abrams, D. I., H. P. Vizoso, S. B. Shade, C. Jay, M. E. Kelly, and N. L. Benowitz. "Vaporization as a Smokeless Cannabis Delivery System: A Pilot Study." Clinical Pharmacology & Therapeutics 82, no. 5 (2007): 572–78. http://dx.doi.org/10.1038/sj.clpt.6100200.

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Hallinan, Christine Mary, and Yvonne Ann Bonomo. "The Rise and Rise of Medicinal Cannabis, What Now? Medicinal Cannabis Prescribing in Australia 2017–2022." International Journal of Environmental Research and Public Health 19, no. 16 (2022): 9853. http://dx.doi.org/10.3390/ijerph19169853.

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Medicinal cannabis was legalised in Australia in November 2016. By August 2022, there were 5284 specialist physician and general practitioner (GP) prescribers who submitted Special Access Scheme (SAS) applications to the Therapeutic Goods Administration (TGA) for the provision of medicinal cannabis prescriptions their patients. In this article we examine the impact of the delivery of publicly available clinical guidance documents, provision of education to prescribers, establishment of the TGA online portal, and launching of cannabis clinics on the number of applications approved by the TGA ov

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Casey, Sherelle L., Vanessa A. Mitchell, Eddy E. Sokolaj, Bryony L. Winters та Christopher W. Vaughan. "Intrathecal Actions of the Cannabis Constituents Δ(9)-Tetrahydrocannabinol and Cannabidiol in a Mouse Neuropathic Pain Model". International Journal of Molecular Sciences 23, № 15 (2022): 8649. http://dx.doi.org/10.3390/ijms23158649.

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(1) Background: The psychoactive and non-psychoactive constituents of cannabis, Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), synergistically reduce allodynia in various animal models of neuropathic pain. Unfortunately, THC-containing drugs also produce substantial side-effects when administered systemically. We examined the effectiveness of targeted spinal delivery of these cannabis constituents, alone and in combination. (2) Methods: The effect of acute intrathecal drug delivery on allodynia and common cannabinoid-like side-effects was examined in a mouse chronic constriction injury (

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Hyatt, Andrew S., Lindsay Overhage, and Benjamin Lê Cook. "Use of Tobacco and Cannabis Following State-Level Cannabis Legalization." JAMA Network Open 8, no. 7 (2025): e2520093. https://doi.org/10.1001/jamanetworkopen.2025.20093.

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ImportanceCannabis use has been shown to modestly increase shortly after legalization of recreational use, but little is known about longer-term changes in cannabis and tobacco use.ObjectiveTo assess the association of cannabis legalization and commercialization with the use of cannabis, cigarettes, and electronic nicotine delivery systems (ENDS) in the 5 years after legalization in the US.Design, Setting, and ParticipantsThe Population Assessment of Tobacco and Health (PATH) study, a nationally representative longitudinal cohort study of adults 18 years or older in the US, was used for a retr

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Young-Wolff, Kelly C., Tara R. Foti, Andrea Green, et al. "Perceptions About Cannabis Following Legalization Among Pregnant Individuals With Prenatal Cannabis Use in California." JAMA Network Open 5, no. 12 (2022): e2246912. http://dx.doi.org/10.1001/jamanetworkopen.2022.46912.

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ImportanceAs rates of prenatal cannabis use increase and cannabis legalization spreads across the US, studies are needed to understand the potential impacts of legalization from the perspectives of pregnant individuals who use cannabis.ObjectiveTo characterize pregnant individuals’ perspectives on legalization of cannabis for adult use in California (effective in 2018) in relation to prenatal cannabis use behaviors and beliefs.Design, Setting, and ParticipantsThis qualitative study was conducted in Kaiser Permanente Northern California, a large health care system with universal screening for s

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Ramlawi, Serine, Malia S. Q. Murphy, Alysha L. J. Dingwall-Harvey, et al. "Cannabis Use in Pregnancy and Downstream effects on maternal and infant health (CUPiD): a protocol for a birth cohort pilot study." BMJ Open 12, no. 12 (2022): e066196. http://dx.doi.org/10.1136/bmjopen-2022-066196.

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IntroductionCannabis use in pregnancy and post partum is increasing. Accessibility to cannabis has expanded due to the legalisation of cannabis in Canada. Therefore, there is a critical need to monitor the impact of cannabis on pregnancy outcomes and infant neurodevelopment. This pilot study will assess the feasibility of modern recruitment and data collection strategies adapted to the current cannabis environment and inform the design of a multicentre prospective birth cohort.Methods and analysisWe will establish a pregnancy and birth cohort of 50 cannabis users and 50 non-users recruited bef

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Smith, Danielle M., Jesse T. Kaye, Kyle J. Walters, et al. "Tobacco–cannabis co-use among cancer patients and survivors: findings from 2 US cancer centers." JNCI Monographs 2024, no. 66 (2024): 234–43. http://dx.doi.org/10.1093/jncimonographs/lgad035.

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Abstract Background Cannabis use is prevalent among cancer patients and survivors and may provide some therapeutic benefits for this population. However, benefits may be attenuated when cannabis is co-used with tobacco, which is associated with more severe tobacco and cannabis use and adverse outcomes in noncancer populations. We compared cannabis use, primary mode of use, and therapeutic and/or nontherapeutic use among 3 groups of patients and survivors based on cigarette smoking status. Methods Survey data was collected from patients and survivors with cancer (n = 1732) at 2 US National Canc

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McClements, David Julian. "Enhancing Efficacy, Performance, and Reliability of Cannabis Edibles: Insights from Lipid Bioavailability Studies." Annual Review of Food Science and Technology 11, no. 1 (2020): 45–70. http://dx.doi.org/10.1146/annurev-food-032519-051834.

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The legal sale of cannabis-enriched foods and beverages for medical or recreational purposes is increasing in many states and countries, especially in North America and Europe. These food-based cannabis delivery systems vary considerably in their compositions and structures, ranging from low-viscosity watery beverages to solid fatty chocolates. The rate and extent of release of the bioactive components in cannabis within the human gastrointestinal tract (GIT) affect their health and psychoactive effects. Studies with other types of hydrophobic bioactives, such as nutraceuticals and vitamins, h

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Newmeyer, Matthew N., Madeleine J. Swortwood, Allan J. Barnes, Osama A. Abulseoud, Karl B. Scheidweiler, and Marilyn A. Huestis. "Free and Glucuronide Whole Blood Cannabinoids' Pharmacokinetics after Controlled Smoked, Vaporized, and Oral Cannabis Administration in Frequent and Occasional Cannabis Users: Identification of Recent Cannabis Intake." Clinical Chemistry 62, no. 12 (2016): 1579–92. http://dx.doi.org/10.1373/clinchem.2016.263475.

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Abstract BACKGROUND There is increasing interest in markers of recent cannabis use because following frequent cannabis intake, Δ9-tetrahydrocannabinol (THC) may be detected in blood for up to 30 days. The minor cannabinoids cannabidiol, cannabinol (CBN), and THC-glucuronide were previously detected for ≤2.1 h in frequent and occasional smokers' blood after cannabis smoking. Cannabigerol (CBG), Δ9-tetrahydrocannabivarin (THCV), and 11-nor-9-carboxy-THCV might also be recent use markers, but their blood pharmacokinetics have not been investigated. Additionally, while smoking is the most common a

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Langley, Paul. "Establishing Credibility for Medical Marijuana: The Proposed Prometheus Dispensary Registry for Botanical Cannabis." INNOVATIONS in pharmacy 10, no. 1 (2019): 2. http://dx.doi.org/10.24926/iip.v10i1.1553.

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A previous commentary in INNOVATIONS in Pharmacy argued that, given the lack of evidence for outcomes in medical marijuana, outside of a handful of randomized clinical trials and even fewer observational studies, good clinical practice points to the need for monitoring patients who received cannabis through certified medical marijuana dispensaries. The commentary noted the lack of standards for monitoring cannabis patients and the lack of feedback from the dispensary to providers. Botanical cannabis administration was occurring in, effectively, an evidence vacuum. More to the point, dispensary

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Akshay, Wagh* Kunal Kothawade Shivshankar Ambhore Dr. Avinash Darekar. "Comprehensive Pharmacological Study of Cannabis Sativa Plant." International Journal of Scientific Research and Technology 2, no. 4 (2025): 636–45. https://doi.org/10.5281/zenodo.15295450.

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Cannabis, also known as marijuana, contains several chemicals, especially Δ-9 tetrahydrocannabinol and cannabidiol, that may have therapeutic and medical benefits. Though few of them are cardiovascular in nature, cannabis may have medicinal advantages. On the other hand, cardiovascular disorders are among the many alarming health effects of cannabis, however delivery systems may play a role.  This statement assesses the safety and efficacy profile of cannabis, especially in regard to cardiovascular health, and critically examines its usage for medical and recreational purposes from

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Duggan, Peter J. "The Chemistry of Cannabis and Cannabinoids." Australian Journal of Chemistry 74, no. 6 (2021): 369. http://dx.doi.org/10.1071/ch21006.

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The science of cannabis and cannabinoids encompasses a wide variety of scientific disciplines and can appear daunting to newcomers to the field. The encroachment of folklore and ‘cannabis culture’ into scientific discussions can cloud the situation further. This Primer Review is designed to give a succinct overview of the chemistry of cannabis and cannabinoids. It is hoped that it will provide a useful resource for chemistry undergraduates, postgraduates and their instructors, and experienced chemists who require a comprehensive and up to date summary of the field. The Review begins with a bri

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Bagot, Kara, Elizabeth Hodgdon, Natasha Sidhu, et al. "End User–Informed Mobile Health Intervention Development for Adolescent Cannabis Use Disorder: Qualitative Study." JMIR mHealth and uHealth 7, no. 10 (2019): e13691. http://dx.doi.org/10.2196/13691.

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Background The rates of cannabis use continue to increase among adolescents and the current interventions have modest effects and high rates of relapse following treatment. There is increasing evidence for the efficacy of mobile technology–based interventions for adults with substance use disorders, but there is limited study of this technology in adolescents who use cannabis. Objective The goal of our study was to elucidate elements of an app-based adjunctive intervention for cannabis cessation that resonate with adolescents who use cannabis. Methods Adolescents, aged between 14 and 17 years,

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Parris, Urica. "An Access to Care Center as a Learning Organization." Healthcare Management Forum 13, no. 1 (2000): 50–52. http://dx.doi.org/10.1016/s0840-4704(10)60733-8.

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The Durham Access to Care (DATC) is one of the new streamlined vehicles for the delivery of integrated home-based and community-based health services across Ontario. Management and staff in this change transition have undertaken to become a learning organization. To implement this visionary process leadership qualities and style is key. This article gives a brief account of DATC and its move to becoming a learning organization and the author's observational reflections of an effective leadership style.

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Stasiłowicz-Krzemień, Anna, Daria Szymanowska, Piotr Szulc, and Judyta Cielecka-Piontek. "Antimicrobial, Probiotic, and Immunomodulatory Potential of Cannabis sativa Extract and Delivery Systems." Antibiotics 13, no. 4 (2024): 369. http://dx.doi.org/10.3390/antibiotics13040369.

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The compounds present in hemp show multidirectional biological activity. It is related to the presence of secondary metabolites, mainly cannabinoids, terpenes, and flavonoids, and the synergy of their biological activity. The aim of this study was to assess the activity of the Henola Cannabis sativae extract and its combinations with selected carriers (polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol graft copolymer, magnesium aluminometasilicate, and hydroxypropyl-β-cyclodextrin) in terms of antimicrobial, probiotic, and immunobiological effects. As a result of the conducted resear

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Carrara, Laura, Christian Giroud, and Nicolas Concha-Lozano. "Development of a Vaping Machine for the Sampling of THC and CBD Aerosols Generated by Two Portable Dry Herb Cannabis Vaporisers." Medical Cannabis and Cannabinoids 3, no. 1 (2020): 84–94. http://dx.doi.org/10.1159/000505027.

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Cannabis sativa is known for its recreational use, but also for its therapeutic potential. There has been wide discussion over the use of cannabis for medical purposes in recent years, especially because a consensus has not been reached regarding its risk/benefit balance. Among the more common modes of administration, vaping with a vaporiser is most frequently used for self-medication. Vaping seems to be a better alternative to preventing adverse health effects due to toxic compounds produced during combustion when cannabis is smoked. However, the delivery kinetics and efficiency of most porta

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Goulette, Michelle, Nicolas J. Schlienz, Amy Case та ін. "Abstract 6472: Self-reported knowledge of Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) potency in cannabis products among cancer patients and survivors: Results from a survey of cannabis consumers at an NCI-designated cancer center". Cancer Research 83, № 7_Supplement (2023): 6472. http://dx.doi.org/10.1158/1538-7445.am2023-6472.

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Abstract Background: Cannabis use may introduce risks and/or benefits to cancer patient treatment and survivorship, depending on product type, composition and nature of its use. Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are two primary cannabinoids that elicit therapeutic effects, but only THC has abuse potential, highlighting the importance of patient knowledge of cannabinoid potency in patient-provider interactions and provider risk-benefit assessments. This study aims to understand factors associated with knowledge of THC or CBD potency in cannabis products among a sample of cance

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Padon, Alisa, Kelly Young-Wolff, Lyndsay Avalos, and Lynn Silver. "Local Laws Regulating Cannabis in California Two Years Post Legalization: Assessing Incorporation of Lessons from Tobacco Control." Cannabis 5, no. 3 (2022): 47–60. http://dx.doi.org/10.26828/cannabis/2022.03.005.

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Introduction: As cannabis legalization continues to spread, best regulatory practice remains ill-defined and elusive, exposing the population to potential harms. Methods: We conducted an annual, statewide, cross-sectional survey to assess cannabis-related laws in effect by January 1, 2020, in local California jurisdictions and at the state level and measured adoption of potential best practices. Results: The current laws of all 539 jurisdictions were located; 276 jurisdictions allowed any retail sales (storefront or delivery) covering 58% of the population, an increase of 20 jurisdictions (8%)

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Hartman, Rebecca L., Timothy L. Brown, Gary Milavetz, et al. "Controlled Cannabis Vaporizer Administration: Blood and Plasma Cannabinoids with and without Alcohol." Clinical Chemistry 61, no. 6 (2015): 850–69. http://dx.doi.org/10.1373/clinchem.2015.238287.

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Abstract BACKGROUND Increased medical and legal cannabis intake is accompanied by greater use of cannabis vaporization and more cases of driving under the influence of cannabis. Although simultaneous Δ9-tetrahydrocannabinol (THC) and alcohol use is frequent, potential pharmacokinetic interactions are poorly understood. Here we studied blood and plasma vaporized cannabinoid disposition, with and without simultaneous oral low-dose alcohol. METHODS Thirty-two adult cannabis smokers (≥1 time/3 months, ≤3 days/week) drank placebo or low-dose alcohol (target approximately 0.065% peak breath-alcohol

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Al-Husinat, Lou’i, Shrouq Obeidat, Saif Azzam, et al. "Role of Cannabis in the Management of Chronic Non-Cancer Pain: A Narrative Review." Clinics and Practice 15, no. 1 (2025): 16. https://doi.org/10.3390/clinpract15010016.

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Chronic non-cancer pain, defined by the Center for Disease Control and Prevention (CDC) as lasting beyond three months, significantly affects individuals’ quality of life and is often linked to various medical conditions or injuries. Its management is complex. Cannabis, containing the key compounds Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), has garnered interest for its potential in pain management, though it remains controversial due to its psychoactive effects and illegal status in many countries. THC provides pain relief by blocking nociceptive stimuli but has psychoactive ef

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Sinclair, Justin, Laura Collett, Jason Abbott, David W. Pate, Jerome Sarris, and Mike Armour. "Effects of cannabis ingestion on endometriosis-associated pelvic pain and related symptoms." PLOS ONE 16, no. 10 (2021): e0258940. http://dx.doi.org/10.1371/journal.pone.0258940.

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Background The use of cannabis for symptoms of endometriosis was investigated utilising retrospective archival data from Strainprint Technologies Ltd., a Canadian data technology company with a mobile phone application that tracks a range of data including dose, mode of administration, chemovar and their effects on various self-reported outcomes, including pelvic pain. Methods A retrospective, electronic record-based cohort study of StrainprintTM users with self-reported endometriosis was conducted. Self-rated cannabis efficacy, defined as a function of initial and final symptom ratings, was i

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Banbury, Samantha, Hannah Tharmalingam, Joanne Lusher, Simon Erridge, and Chris Chandler. "A Preliminary Investigation into the Use of Cannabis Suppositories and Online Mindful Compassion for Improving Sexual Function Among Women Following Gynaecological Cancer Treatment." Medicina 60, no. 12 (2024): 2020. https://doi.org/10.3390/medicina60122020.

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Background and Objectives: The impact of gynaecological cancer and its treatments on sexual intimacy can be profound on female sexuality. However, very few registered clinical trials have addressed sexual intimacy among this cohort. Materials and Methods: This preliminary randomised control trial (RCT) and content analysis assessed the effectiveness of a brief online mindful compassion group intervention adjunct with cannabis suppositories. Eighty-three participants aged between 18 and 50+ years who were at least six months post-cancer treatment were randomly allocated to one of four groups, d

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Clarke, Stephen John, Luis Vitetta, Andrew J. McLachlan, Jeremy David Henson, David Rutolo, and Sean Hall. "An oro-buccal nanoparticle delivered cannabis medicine for pain management in cancer: A clinical trial in progress." Journal of Clinical Oncology 38, no. 15_suppl (2020): TPS12127. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.tps12127.

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TPS12127 Background: Cannabinoid molecules derived from Cannabis sativa L. have been posited to ameliorate conditions, including pain, chemotherapy induced nausea and multiple sclerosis associated spasticity. The clinical use of cannabinoids refers to a wide variety of formulations and extracts that may contain different active ingredients and adulterants as well as inter batch variability. Novel matrix formulations (e.g., water-soluble nanoparticles) for cannabis delivery may add further efficacy and tolerability to standard routes of administration (e.g., oral / gastrointestinal, inhaled, su

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Stefaniak, Aleksandr B., Ryan F. LeBouf, Anand C. Ranpara, and Stephen S. Leonard. "Toxicology of flavoring- and cannabis-containing e-liquids used in electronic delivery systems." Pharmacology & Therapeutics 224 (August 2021): 107838. http://dx.doi.org/10.1016/j.pharmthera.2021.107838.

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Gieringer, Dale, Joseph St. Laurent, and Scott Goodrich. "Cannabis Vaporizer Combines Efficient Delivery of THC with Effective Suppression of Pyrolytic Compounds." Journal of Cannabis Therapeutics 4, no. 1 (2004): 7–27. http://dx.doi.org/10.1300/j175v04n01_02.

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