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Phillips, Michael. "The family album : an extended portrait /." Online version of thesis, 1987. http://hdl.handle.net/1850/8851.
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Elliott, Diana B. "How nuclear is the nuclear family? extended family investments in children /." College Park, Md.: University of Maryland, 2008. http://hdl.handle.net/1903/8753.
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Thesis (Ph. D.) -- University of Maryland, College Park, 2008.Thesis research directed by: Dept. of Sociology. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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Wronka, Agata Ewa. "Separatrix splitting for the extended standard family of maps." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5043.
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This thesis presents two dimensional discrete dynamical system, the extended standard family of maps, which approximates homoclinic bifurcations of continuous dissipative systems. The main subject of study is the problem of separatrix splitting which was first discovered by Poincaré in the context of the n-body problem. Separatrix splitting leads to chaotic behaviour of the system on exponentially small region in parameter space. To estimate the size of the region the dissipative map is extended to complex variables and approximated by differential equation on a specific domain. This approach was proposed by Lazutkin to study separatrix splitting for Chirikov’s standard map. Furthermore the complex nearly periodic function is used to estimate the width of the exponentially small region where chaos prevails and the map is related to the semistandard map. Numerical computations require solving complex differential equation and provide the constants involved in the asymptotic formula for the size of the region. Another problem studied in this thesis is the prevalence of resonance for the dissipative standard map on a specific invariant set, which for one dimensional map corresponds to a circle. The regions in parameter space where periodic behaviour occurs on the invariant set is known as Arnold tongues. The width of Arnold tongue is studied and numerical results obtained by iterating the map and solving differential equation are related to the semistandard map.
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Asonibare, Stephen. "Using extended family dynamics to grow the Nigerian church." Online full text .pdf document, available to Fuller patrons only, 2000. http://www.tren.com.
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Eldali, Salma, and Samuele Francesco Maria Sicali. "Absorptive Capacity in Family Firms : A quantitative study on Absorptive Capacity, R&D activities and patents in Family Firms." Thesis, Högskolan i Jönköping, Internationella Handelshögskolan, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-39917.
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Background: Absorptive capacity concept has its roots dated back around 30 years ago when two seminal papers were published. During the years, more knowledge has been produced about this topic. However, most of the studies have focused on the absorptive capacity from a general point of view without correlating it with the R&D activities of family firms and family involvement. Purpose: This study investigates how one of the distinctive characteristics of family firms (i.e. family involvement) plays a role along with R&D activities carried out either in-house or from external sources, in filing for a patent. Method: To conduct our study we adopted a quantitative approach and used secondary data about 14759 firms located in EU. Considering the type of selected variables, for our analysis we used logistic regression in order to see if the model we proposed was meaningful or not. Conclusion: The findings from our study address the research questions we formulated at the beginning. As for the R&D we conclude that family firms take more advantage from carrying out in-house R&D activities rather than R&D from external sources, matching with what claimed in the existing literature. Furthermore, our study matches with recent studies that challenge the traditional view of family involvement negatively related to innovation.
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Boltz, Marie. "Informal Redistribution and Savings in the Extended Family in Senegal." Paris, EHESS, 2015. http://www.theses.fr/2015EHES0128.
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Cette thèse porte sur l'analyse des normes de redistribution au sein de la famille élargie en Afrique Sub-Saharienne et de leurs impacts sur les choix d'allocation des ressources entre individus. Dans un contexte où les marchés financiers sont peu développés et où les revenus sont très volatiles, les individus sont vulnérables face aux risques économiques et de la vie. Pour pallier ces risques, ils se reposent alors principalement sur deux stratégies : la redistribution intrafamiliale et l'épargne. Dans cette thèse, j'étudie comment les mécanismes de redistribution intrafamiliale affectent les décisions d'épargne. A partir d'une enquête qualitative originale conduite au Sénégal en 2012, le premier chapitre propose une analyse fine de la relation entre les migrants, principaux contributeurs aux dépenses du ménage d'origine, et les destinataires de leurs transferts afin de mieux comprendre la dynamique du partage de ressources et les normes sociales qui y sont jointes. Dans le second chapitre, j'étudie les décisions de transferts au sein de la fratrie et comment elles permettent d'expliquer les choix d'épargne. J'utilise les données représentatives à l'échelle nationale de l'enquête "Pauvreté et Structure Familiale' au Sénégal. Je montre l'importance de transferts notamment destinés à des cérémonies, qui sont associés pour les hommes par un niveau d'épargne plus faible. Dans le troisième chapitre, je mets en évidence l'existence de stratégies coûteuses visant à réduire la pression à redistribuer, à partir d'une expérimentation originale au Sénégal. Une forte disposition marginale à payer pour cacher ses revenus est observée. De plus, les personnes ayant reçues leurs gains en privé transfèrent moins à leur entourage et compensent par d'avantage de dépenses personnelles. Enfin, dans le chapitre 4, il s'agit de comprendre comment les changements anticipés dans la situation matrimoniale du ménage peuvent influencer les comportements d'épargne et d'investissement. En particulier, je montre que les femmes en union monogame, face au risque de l'entrée d'une seconde femme dans leur union, investissent dans des stratégies visant à se protéger économiquement, en accumulant davantage d'épargne et concentrant leurs dépenses sur leurs besoins personnels et l'éducation de leurs enfantsThis PhD dissertation aims at analyzing the effect of informal redistribution, taking mostly place within the extended family, on individuals' resource allocation choices in Sub-Saharan Africa. Indeed, in this region, due to limited access to markets for insurance, credit and savings, and to formal redistribution, individuals are vulnerable to life risks and economic shocks. To protect themselves against these risks, individuals rely mainly on two strategies: informal redistribution and informal savings. I analyze in this thesis how informal redistribution within the extended family affects individual savings decisions. The first chapter is based on an original qualitative survey conducted in Senegal in 2012 and propose a detailed analysis of the relationship between the transfer senders and the recipients within several family networks to understand the dynamics of resource sharing in the extended family and the social norms attached to these transfers. In the second Chapter, I investigate transfer patterns within a sibship and analyze how these patterns are related to saving decisions, using the nationally-representative ' Pauvrete et Structure Familiale' (PSF) suvey in Senegal. I find some evidence of high redistributive obligations that come generally at the cost of lower savings achieved for the main transfer senders. Based on an original lab experiment, in the third chapter, I highlight the widespread use of costly strategies aimed at circumventing these redistributive norms, namely income hiding. I identify the distortionary effects of such strategies on resource allocation decisions. In particular, I elicit a high willingness-to-pay to hide income from peers in the lab and show that hidden income induce a lower share of the gains devoted to transfers out of the lab, compensated by an increase in personal expenses. Finally, in my last chapter, using the panel of individuals of the PSF survey, I show that monogamous wives, when facing a higher risk of becoming polygamous, invest in self-protective strategies by saving more and spending more on personal expenses and on the education of their children
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Martin, Sheryl. "Grandparents Raising Grandchildren: The Lived Experience of Extended Family Reconciliation." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2991.
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Researchers have documented the increasing role of grandparents who provide care for their grandchildren; however, few have studied extended family reconciliation after grandparents assumed their primary care. This study explored the reconciliation experiences of 12 grandparents who were primary caretakers of their grandchildren. Using Moustakas's phenomenological research approach, the participants were interviewed about their experiences of the relationship triad (grandparent-grandchild, grandparent-adult child, parent-child). Attachment theory and family systems theory were the conceptual frameworks to explore the central research question, which addressed the meaning of extended family reconciliation for grandparents who become primary caregivers of grandchildren. Using NVivo, the interview data were coded and grouped into themes of shared meaning. The results revealed 4 distinct themes: watching my adult child struggle; recognizing challenges; my grandchild's wellbeing; and communicating with my grandchild. Further, the lived experience revealed that extended family reconciliation was largely dependent upon the adult child's willingness, readiness, and capability to participate in the reconciliation process. Results of this study have the potential to benefit children in their grandparents' care by providing insights into the reconciliation experience, with meaningful results to be shared with the professional community and grandparents who care for their grandchildren.
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Kang, Jeehye. "Behavioral Problems of Children in L.A| Extended Family, Neighborhood, and Nativity." Thesis, University of Maryland, College Park, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10286698.
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This dissertation consists of three papers that examine the association between family living arrangements and internalizing and externalizing behavioral problems in children. With increasing immigration and growing heterogeneity in family forms, extended family members are of increasing importance in children’s lives. However, knowledge about extended family living arrangements is lacking. The first paper examines the association between the presence of co-resident extended kin and children’s internalizing and externalizing behaviors. Children in the sample were found to be disadvantaged in extended households, especially with regard to internalizing behaviors. This association was found mostly among married-parent extended households. Further, this pattern emerged more clearly among children of documented immigrants, compared to those with native-born parents and those whose parents were undocumented immigrants. These findings suggest a need to revisit previous theories on extended family living arrangements. The second paper examines what kinds of household extension are associated with child behavioral problems. I specify the types of household extension by their relation to the householder—vertical, horizontal, and non-kin. Results from the cross-sectional sample indicate that horizontal extension is associated with higher internalizing behavior problems in children. However, the results from fixed effects models suggest that this pattern may be due to selection effects. Fixed effects estimations show that children moving into vertically extended household increase externalizing behaviors or that children moving out of a vertically extended household decrease externalizing behaviors. I discuss what implications this type of transition represents. The third paper examines the interaction between extended family household structure and neighborhood characteristics on children’s behavioral functioning. Findings suggest that the co-residence with extended kin is associated with both higher internalizing and externalizing behaviors for children. Although the health disadvantage of living with extended kin seems to be independent of the neighborhood income and racial minority concentration levels, extended kin moderate the associations with neighborhood structure. The advantage of living in higher-income neighborhood strengthens for extended families, reducing internalizing behavioral problems in children. Minority concentrated neighborhood functions as an advantage for extended families, decreasing externalizing behavioral problems. I conclude with discussion of future research and policy implications.
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Tolliver, Robert M., Gayatri Jaishankar, and Jodi Polaha. "Champion Teams as a Mechanism for Developing Team Care Capacity." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/6557.
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"Practice transformation" toward team care as a singular undertaking can be daunting. In this presentation, we describe the development of a mechanism for small, iterative and sustainable practice changes toward team care known as "Champion Teams." Champion Teams are based on the Institute of Medicine's "learning health care system" approach in which practitioners develop an internal mechanism for and culture around digesting and implementing new evidence based practices on an ongoing basis. In addition to presenting the Champion Team concept as a strategy for implementing new team care initiatives, interprofessional providers will present two case examples from each adult and pediatric primary care. At the conclusion of this presentation, participants will be able to: Define the term "learning healthcare system" and its application to Champion Teams. Describe the utility of and keys to implementing Champion Teams. Describe two examples of Champion Teams and the application of this mechanism to making data-informed changes toward team-based care in their own setting.
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Trivette, Carol M., and Bonnie Keilty. "DEC Family Recommended Practices: Knowing Families, Tailoring Practices, Building Capacity." Digital Commons @ East Tennessee State University, 2017. http://pubs.cec.sped.org/s6284/.
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The Division for Early Childhood (DEC) Recommended Practices provide guidance to families and professionals about the most effective ways to improve learning outcomes and promote development of young children, birth through age 5, who have, or are at risk for, developmental delays or disabilities. Family: Knowing Families, Tailoring Practices, Building Capacity is the third edition of the DEC Recommended Practices Monograph Series, and it offers professionals and families multiple ways to implement the family practices across the settings in which children grow and learn. The articles in this collection provide guidance by illustrating how to implement the Family Recommended Practices with fidelity and flexibility. The monograph offers a unique contribution to the field by including authentic family voices as primary or equal contribution.
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Diaz, Ashley M., and Melodie Anne Chronister. "KNOWLEDGE AND USE OF FAMILY PLANNING SERVICES BY EXTENDED FOSTER CARE CLIENTS." CSUSB ScholarWorks, 2015. https://scholarworks.lib.csusb.edu/etd/160.
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There has been extensive, mostly negative research on the outcomes of foster care youth. Due to the abundance of this research, Extended Foster Care (EFC) was created to help to provide additional resources and support to young adults in foster care until age 21. This is a fairly new program, therefore little research has been completed. One of the negative outcomes of foster youth is the high pregnancy and parenting rates. The purpose of this study is to be able to understand the knowledge and use of family planning services among the young adults participating in EFC. Understanding this information will help to improve services provided by the social workers who work with this population. This research used a quantitative questionnaire. The questionnaire was mailed to the young adults participating in EFC in San Bernardino County. A statistical analysis was completed using SPSS version 21. The study’s findings showed that on average, EFC participants have a good understanding of safe-sex practices but do not usually use safe-sex methods or go to family planning service organizations. The study also found that participant demographics do not have a correlation to their knowledge or use of family planning services, nor to the number of pregnancies or live births. However, there is a negative correlation between a participant's knowledge score and if they have children in their custody. Finally, 47% of participants reported being informed about family planning service organizations by their Social Worker.
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Mishra, Prakash. "Studies on the role of the Extended-Synaptotagmin Gene Family in vivo." Doctoral thesis, Université Laval, 2015. http://hdl.handle.net/20.500.11794/26016.
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La signalisation cellulaire est un processus fondamental par lequel les organismes multicellulaires assurent un développement normal et maintiennent leur homéostasie. La communication entre les divers organites joue un rôle crucial en ce sens. Les sites de contact membranaires (SCM), régions de proche apposition entre deux organites (environ 20 nm), sont importants dans le maintien de la communication inter-organite. Une étude minutieuse de cette communication est indispensable pour comprendre certains fascinants mystères de la nature. Récemment, les protéines apparentées aux synaptotagmines (ESyt) ont été identifiées comme étant des protéines résidentes au niveau du Réticulum Endoplasmique (RE) et impliquées dans le maintien des sites de contact entre le RE et la Membrane Plasmique (RE-PM). Trois protéines appartiennent à cette famille, dénommées ESyt1-3. Celles-ci sont également impliquées dans la reconnaissance des récepteurs conduisant à l’endocytose du récepteur et la signalisation en aval. Dans ce manuscrit, nous présentons l’interaction des ESyt avec FGFR1-4, EGFR ainsi que le récepteur MET et proposons que les ESyt interagissent avec de nombreux récepteurs tyrosine-kinases (RTK). Nous avons montré que les membres de la famille ESyt (ESyt1, ESyt2a et ESyt2b (variant d’épissage) et ESyt3) sont capables d'homo- et hétéro-dimérisé via leurs séquences proximales à, ou chevauchantes leur domaine transmembranaire (TM) (a.a. 88 à 138). De plus, il a été montré que l'interaction de ESyt2 avec FGFR1 est dépendante de l'état actif du récepteur. Cependant, l'autophosphorylation du récepteur ou son activation catalytique per se ne sont pas requises. Le site de liaison à ESyt2 sur FGFR1 est proche du site de liaison à l'ATP au sein du lobe supérieur du domaine catalytique du récepteur. Il devient accessible lorsque la boucle d'activation est déplacée dans sa conformation active. Le site d'interaction sur ESyt2 se situe dans la même région que la séquence nécessaire à la dimérisation de ESyt (a.a 88 à 138) et ne requière pas le domaine SMP adjacent. Finalement, nous montrons que la perte de ESyt2 et Esyt3 n’affecte ni le développement ni la viabilité chez la souris, malgré que la migration cellulaire et la survie sont affectées suite à des stress in vitro.Cellular signaling is one of the fundamental process by which multicellular organisms maintain their normal development and homeostasis. Inter-organelle communication plays a crucial role in governing such processes. Membrane contact sites (MCS), a region where two organelles come in close proximity (within ≈20nm), helps in maintaining the inter-organelle communication. A thorough study of inter-organelle communication is required to understand some of the wonderful mysteries of nature. Recently Extended Synaptotagmin-like proteins (ESyts) have been found to be Endoplasmic Reticulum (ER) resident proteins that have been attributed the function of maintaining the ER-Plasma Membrane (ER-PM) contact sites. Three proteins belong to this family, namely ESyt1 to 3. Further, ESyts have been implicated in receptor recognition, receptor endocytosis and downstream signaling. Here I present the interaction of ESyts with FGFR1-4, EGFR and the MET receptor and propose that ESyts interact with a broad range of receptor tyrosine kinases (RTKs). The members of ESyt family (ESyt1, ESyt2a and ESyt2b (spliced variants), and ESyt3) are shown to homo- and heterodimerize via sequences proximal or overlapping their transmembrane domains (TM) (a.a. 88 to 138). It is shown that the interaction of ESyt2 with FGFR1 is dependent on the active state of the receptor. In contrast, neither receptor autophosphorylation nor catalytic activation per se is required. Rather, the interaction depends upon the active conformation of the receptor catalytic domain. The ESyt2 binding site on FGFR1 lies close to its ATP binding fold within the upper lobe of the receptor catalytic domain and is revealed when the receptor activation loop is displaced into the active conformation. The interaction site on ESyt2 lies within the same sequences that are required for ESyt dimerization (a.a. 88 to 138) and does not require the adjacent SMP homology domain. Finally, it is shown that the loss of ESyt2 and ESyt3 does not affect mouse development or viability. However, in vitro cell migration and survival under stress are affected.
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Jansen, Kayla. "Extended Family Relationships: How They Impact the Mental Health of Young Adults." UKnowledge, 2017. http://uknowledge.uky.edu/hes_etds/49.
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This study bridges the gap in literature about the impact of extended family relationships on young adult depression and self-esteem. A sample of 304 undergraduate students between the ages of 18 and 21 at the University of Kentucky was recruited to complete an online survey about their immediate and extended family relationships and their mental health. The largest predictor of self-esteem and depression in early young adults is perceived social support from the family of origin, which is also moderately correlated with perceived support from extended family members. This indicates that extended family support collaborates with family of origin support to benefit self-esteem and depression levels. Depression also decreases through more positive interactions with extended family members. Males benefited less than females from extended family relationships, as evidenced by the result that closer extended kin relationships were the second largest predictor of more depressive symptoms in males. These findings inform therapists about effective ways of conducting therapy with college students and support the use of Bowen family systems therapy.
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Lean, Kirstin. "Creating family resilience?" Thesis, University of Exeter, 2012. http://hdl.handle.net/10036/3395.
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The balance between family support and child protection services is continuously challenged by high-profile cases. These highlight shortcomings both of the UK system and of research on the effectiveness of child maltreatment interventions (Munro, 2011). One such intervention is the Resolutions Approach to ‘denied’ child abuse (Turnell and Essex, 2006) – a systemic approach which creates a support network including extended family, friends, community members and professionals. There is, however, only limited research analysing the supporters’ experience of this intervention. In the present study five semi-structured group interviews were conducted in order to investigate how the family support network members made sense of their participation in Resolutions. Through a thematic analysis three related themes: returning hope; building safety and trusting a professional were identified. Additionally, special attention was paid to processes linked to the creation of family resilience (Walsh, 2003). Based on two contrasting case studies the potential creation of family resilience through Resolutions was discussed and clinical recommendations for creating family resilience within support networks were outlined.
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Palma, Julieta. "Extended living arrangements in Chile : an analysis of subfamilies." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/271737.
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Extended households are far from a rare phenomenon in Latin America and their prevalence does not seem to be in decline. In Chile, they accounted for about a quarter of all households over the 1990–2011 period. This persistence contrasts with the dramatic transformations that have taken place in other dimensions of family life, such as the fall in fertility and marriage rates, and the increase in cohabitation and out-of-wedlock births. Recent studies on extended living arrangements in the region have mainly understood household extension as a strategy to face economic deprivation, giving little attention to other factors affecting it, such as gender inequalities and changing needs for support over the life course. In this dissertation, I contribute to the understanding of extended households Chile through the analysis of adult women living in family units over the 1990–2011 period. Unlike most other studies, I recognise the unequal positions that individuals and families occupy within the extended household, by distinguishing between women that head an extended household and those that join it as subfamilies. Using quantitative methods, I analyse a nationally representative household survey: the CASEN survey. This is the most complete data source on demographic and socioeconomic characteristics of the Chilean population. This dissertation offers a new assessment of the relationship between extended living arrangements and economic deprivation. Its findings only partially support the hypothesis of household extension as a family strategy to face economic hardship. Other key factors emerge when explaining extended living arrangements, including mothers’ full-time employment, the vulnerability of informal family structures, and other needs of support connected to the life course. There has been an increasing trend across 1990–2011 for young women who have started their family life to live in extended households. Multivariate analyses reveals that this increase was mainly influenced by the rising prevalence of cohabitation and single lone motherhood among younger generations, and to a lesser extent by the increase in young women’s full-time employment. These findings raise important theoretical issues for the Chilean context and show that patterns of social modernisation and family change in Chile have gone hand-in-hand with an increasing importance of the support provided by the extended family. This dissertation fills an important gap in the research on intra-household gender inequalities by analysing women’s economic dependence on extended household members. It shows that women in subfamilies are more likely to be economically dependent than those in head-families. Full-time employment, as well as marriage and cohabitation, emerge as highly protective factors against economic dependence. Special attention is paid to lone mothers, who are often excluded from research on women’s economic dependence. Lone mothers in subfamilies benefit economically from being in an extended household. Yet overall they have decreased their likelihood of being economically dependent over the 1990–2011 period. I argue that this reflects the increasing social protection towards lone mothers and recent legal reforms aimed at the equalisation of rights among couples and children irrespective of the marriage bond.
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Polaha, Jodi, Tim Bishop, Leigh Johnson, Reid Blackwelder, Diana Heiman, Gayatri Jaishankar, and Deborah Thibeault. "Champion Teams as a Mechanism for Developing Team Care Capacity." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/6570.
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"Practice transformation" toward team care as a singular undertaking can be daunting. In this presentation, we describe the development of a mechanism for small, iterative and sustainable practice changes toward team care known as "Champion Teams." Champion Teams are based on the Institute of Medicine's "learning health care system" approach in which practitioners develop an internal mechanism for and culture around digesting and implementing new evidence based practices on an ongoing basis. In addition to presenting the Champion Team concept as a strategy for implementing new team care initiatives, interprofessional providers will present two case examples from each adult and pediatric primary care.At the conclusion of this presentation, participants will be able to: Define the term "learning healthcare system" and its application to Champion Teams. Describe the utility of and keys to implementing Champion Teams. Describe two examples of Champion Teams and the application of this mechanism to making data-informed changes toward team-based care in their own setting.
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Kianpour, Saeid. "Syrian Refugee Fathers Perceptions of Identity and Family Dynamics in the U.S. after Displacement." Diss., Virginia Tech, 2019. http://hdl.handle.net/10919/99462.
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At the end of 2016, approximately 65.6 million individuals were displaced forcibly around the world because of generalized violence, persecution, violation of human rights, or conflict such as civil war (UNHCR, 2016). The purpose of this study is to: (a) explore Syrian refugees after displacement in the US, (b) give voice to refugee fathers, and (c) advance knowledge for marriage and family therapists, who are working with refugee families. Eight Syrian refugee fathers who were displaced in the last two years and living in Indiana, US shared their experiences through in-depth interviews. After transcribing and translating the interviews, thematic analysis, a flexible research tool that provides a reach and complex account of data, was used to analyze the data. Four main themes emerged from fathers: displacement stress, loss of extended family connections, experiences of isolation, and identity changes with provider role. A thematic map also is created illustrating how the stress of displacement and being far away from extended families profoundly influence provider identities and family interactions. In addition, the contextual model of family stress is used to customize fathers� experience of displacement. The inferences from this study provide guidance for marriage and family therapists, mental health practitioners, and organizations working with refugee families.PHD
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Cogram, Peter Frank. "Capacity and mechanisms of uptake of silver by jarosite family minerals." Thesis, Birkbeck (University of London), 2017. http://bbktheses.da.ulcc.ac.uk/262/.
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Jarosite is a family of iron-hydroxysulphate minerals that commonly occur in acidic, sulphate-rich environments and in ore processing wastes. Jarosite precipitation is used in hydrometallurgy to control Fe and other impurities. End-member jarosite sensu stricto contains potassium and has the chemical formula KFe3(SO4)2(OH)6, but extensive element substitution takes place in the crystal structure. Silver can be taken up by jarosite minerals and, in theory, Ag can form solid-solution series with K, Na and Pb in jarosite. This study carried out synthesis experiments, using a variety of sulphate starting solutions and temperatures, to form K-jarosite, Na-jarosite and Pbjarosite minerals and determined their capacity for Ag by investigating them using powder X-ray diffraction (XRD), Rietveld refinement, electron microprobe analysis and inductively coupled plasma-atomic emission spectroscopy. Solid solution was found between Ag-jarosite and separately K-jarosite, Na-jarosite and Pb-jarosite, but with substantial hydronium (H3O) content and vacancies in the Fe site. The average relative partitioning coefficients for Ag were 0.9 in K-jarosite, 1.3 in Na-jarosite and 1.17 in Pb-jarosite. Powder XRD analysis showed that, in the K-Ag-H3O and Pb-Ag- H3O-jarosite series, d-spacing values for the hkl 003 and 006 peaks indicated the unitcell c-axis parameter decreased as Ag content increased. Rietveld refinement showed that, in K-Ag-H3O-jarosite and Na-Ag-H3O-jarosite, there were trends of increasing unit-cell a-axis parameters and decreasing c-axis parameters as Ag content increased. Rietveld refinement indicated decreasing K,Ag-O2 and K,Ag-O3 bond lengths as Ag content increased in K-Ag-H3O-jarosite. Raman spectroscopic analysis showed the assigned v1SO4 and v3SO4 vibrational modes in some K-Ag-H3O-jarosite series had higher wavenumbers (cm-1), indicating higher bonding energies, as Ag content increased. The XRD, Rietveld refinement and Raman data from this project will inform the evaluation of the Ag composition of jarosite minerals in complex natural mineral assemblages using these same techniques.
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Piersol, Catherine Verrier. "Examining Caregiver Appraisal of Functional Capacity in Family Members with Dementia." VCU Scholars Compass, 2013. http://scholarscompass.vcu.edu/etd/3131.
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The vast majority of persons with Alzheimer’s disease and related dementias live at home and are cared for by families or close friends/neighbors. An essential element to daily care decisions is the caregiver’s appraisal of function in the family member with dementia. This dissertation comprises three separate papers exploring caregiver appraisal of functional capacity, using secondary data from a study conducted at Thomas Jefferson University of 88 patient-caregiver dyads, funded by the Alzheimer’s Association (L. Gitlin, PhD, principal investigator; Grant # IIRG-07-28686). The caregivers were primarily female (88.6%), white (77.3%), and spouses (55.7%), with a mean age of 65.8. All caregivers had a high school education or higher and had provided care from 6 months to 22 years. The majority of the participants with dementia were female (52.3%) and white (76.1) with a mean age of 81.7. Their scores on the MMSE ranged from 10 to 28 (M = 17.7, SD = 4.6, N = 87). The first paper examined construct and interrater reliability of the Functional Capacity Card Sort (FCCS), a tool designed to measure subjective caregiver appraisal. Using spearman’s rank correlations the FCCS was found to be statistically associated with the Caregiver Assessment of Function and Upset scale (r = .43, p < 0.0001, N = 86) and not statistically associated with the Neuropsychiatric Inventory scale (r = -.14, p = .16, N = 86), supporting convergent and discriminant validity respectfully. Kendall’s coefficient of concordance revealed a strong agreement among caregivers in the ranking of the six cards of the FCCS, Kendall W (5, 72) = 0.83, p = .0001, supporting interrater reliability of the FCCS. The second and third paper demonstrated the utility of the FCCS in distinguishing three groups of caregivers based on their estimation of functional capacity in the person with dementia compared to a gold standard occupational therapy assessment. Fifty-two (61%) of the caregivers overestimated function, 19 (22%) caregivers underestimated function, and 15 (17%) were concordant with the standardized assessment. Further analysis explored personal and home environment factors in relation to caregiver appraisal. The Kruskal-Wallis test showed cognitive status in the person with dementia (H (2, N = 85) = 3.67, p = .16) and caregiver depressive symptoms (H (2, N = 86) = 1.35, p = .51) were not associated with the caregiver’s appraisal of functional capacity in the person with dementia. Linear regression and proportional odds logistic regression, adjusted for cognitive status in the person with dementia, did not reveal a relationship between caregiver appraisal and the number of observed home hazards [F (1, N = 86) = .01, p = .94] or the unmet needs reported by the caregiver [Wald χ2 (1, N = 86) = .95, p = .33], respectively. Linear regression showed a trend towards the hypothesis that caregiver concordant/underestimation of functional capacity have greater home adaptations compared to caregiver overestimation [F (1, N = 86) = 3.06, p = .08]. The papers in totality demonstrate the utility of the FCCS to assess caregiver appraisal and interpret level of estimation, which can guide the therapeutic approach and treatment plan by an occupational therapist or other health professional. Further understanding of caregiver appraisal and associated factors is critical to providing best practice in dementia care. Limitations and future directions for research are discussed.
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Iaboni, Andrea. "An evolutionary and functional analysis of the extended B7 family of costimulatory molecules." Thesis, University of Oxford, 2002. http://ora.ox.ac.uk/objects/uuid:e769d4ab-81c9-4f92-918f-8ddfb718b596.
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Sinclair, Christina. "Sisters, brothers & others : a study of marriage, divorce and extended family relationships." Thesis, University of Cambridge, 1991. https://www.repository.cam.ac.uk/handle/1810/272380.
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Terblanche, Malise Georgette. "The influence of the extended family on the social and moral development of the child in the single parent family." Thesis, Nelson Mandela Metropolitan University, 2014. http://hdl.handle.net/10948/d1020987.
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The single-parent family can no longer be viewed as a non-traditional family type. As more single-parent families become prevalent in our society, interest in this family type has increased. Research associated with single-parent families often focus on the pathology associated with single-parent families. It is apparent that single-parent households, whether headed by a mother or father often have more to deal with than the traditional two-parent family. However, as a single-parent herself, the researcher also knows that this family type has much to offer. This research is undertaken in an exploratory and interpretive manner to illuminate the influence which the extended family have on the social and moral development of the child in the single-parent family. The researcher, just like Monama (2007:iv) before her, wishes to elevate the view of single-parents from the stereotypical victims to responsible archetypes. As this research is undertaken with the eco-systemic perspective of Bronfenbrenner as theoretical orientation, it therefore focuses on the systems in which the child is nested and more specifically the extended family as part of the child’s microsystem. This research aims to be beneficial to single-parents, families, members of community organizations, educators and other allied professionals.
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Hussain, Turab S. M. "Policy analysis and network effects in an extended family model of rural-urban migration." Thesis, University of Essex, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401082.
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Kinser, Amber E. "The Cost of an Education: Exploring the Extended Reach of Academe in Family Life." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/1243.
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Excerpt: Contributors detail what it means to be an academic mother and to think about academic motherhood, while also exploring both the personal and specific institutional challenges academic women face, the multifaceted strategies different academic women are implementing to manage those challenges, and investigating different theoretical possibilities for how we think about academic motherhood.
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Netzel, Katie Sue, and Michelle Becerra Tardanico. "OUTCOMES FOR YOUNG ADULTS IN EXTENDED FOSTER CARE." CSUSB ScholarWorks, 2014. https://scholarworks.lib.csusb.edu/etd/59.
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This study examined the outcomes for young adults in Extended Foster Care. Extended Foster Care is a relatively new program within the Child Welfare system, which provides services for former foster youth between the ages of 18 and 21 to become more successful, independent young adults. Before the implementation of Extended Foster Care in 2012, most of the foster children were left to fend for themselves after they turned 18, which resulted in negative outcomes. Extended Foster Care is a seemingly helpful program; however, due to its new existence there has been very limited research regarding the outcomes of these young adults in Extended Foster Care. This study used secondary data from the San Bernardino County Legislative, Research and Quality Support Services Unit. After data retrieval, independent t-tests and chi-squared tests were conducted using SPSS version 21. The independent variable of days spent in Extended Foster Care was compared to the following dependent variables: disability status, education status, housing status, and employment status and its barriers. The results of this study showed that the longer a young adults stays in Extended Foster Care, the higher their likelihood is of positive housing, employment, and education status. This study suggests it is critical to continue to provide Extended Foster Care services and further research needs to be conducted to ensure program quality and to continue to improve the services to this vulnerable, young adult population.
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Chiimba, Cathrine M. "Experiences of young orphans who transition into extended families in Zimbabwe." Thesis, University of Pretoria, 2020. http://hdl.handle.net/2263/80516.
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This study explores the experiences of young orphans who transition into extended families in Zimbabwe, focusing on the five- to ten-year-old age group. The study embraced a qualitative approach which is situated within the interpretivist paradigm. The choice of the qualitative mode of inquiry was to ensure that the researcher interacted with participants who were remarkably close to young orphans and, henceforth, gather as much reliable and pertinent data as possible. A multiple case study design was employed to investigate five extended family members and their five to ten-year-old young orphans, one social worker and two residential care centre administrators. All five extended families with young orphans lived in the Mutoko, Murewa, Mudzi and Uzumba Maramba Pfungwe (UMP) districts. Data were gathered through interviews, drawings, narratives, and observations. The preference for the research methods were to necessitate a high level of trustworthiness and comprehensive data.
The study established that although the government is mandated to provide services in the transitioning of young orphans into extended families in Zimbabwe, lack of resources inhibit efforts to support these children. Due to lack of funds social workers seldom follow up on young orphans. Although Zimbabwe has well stipulated national, regional and international agreements in its archives on transition, this research study had established that the strained Zimbabwean economy had a negative effect on children who transitioned into extended families. The situation is exacerbated by the fact that extended family members are inadequately prepared and trained to handle young orphans who transition into their families. Furthermore, extended families also face challenges on the scarcity of resources to support young orphans. Young orphans were further challenged by the fact that people stereotyped them because they came from residential care centres. These young orphans also faced several psychological challenges.
The study concluded that both young orphans and extended families are victims of a system that does not have the resources, nor the political and social will to support the transition process. Based on these findings, the recommendations were made for the attention of the government of Zimbabwe, as well as the Department of Social Welfare, who act as executive body in implementing Government’s directives. The study therefore, upholds that extended family members should have relevant skills to enable them to appropriately deal with young orphans. The study further recommends the implementation of policies to take cognisance of the needs of young orphans who transition to extended families are taken on board, as they access appropriate services and resources to mitigate their impediments.Thesis (PhD)--University of Pretoria, 2020.
pt2021
Early Childhood Education
PhD
Unrestricted
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Chavarria, Nicole M., and Denise M. Johnson. "EXPERIENCES OF SUCCESSFUL YOUNG ADULTS IN EXTENDED FOSTER CARE IN SAN BERNARDINO COUNTY." CSUSB ScholarWorks, 2014. https://scholarworks.lib.csusb.edu/etd/53.
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ABSTRACT
This is a qualitative study that was conducted in conjunction with San Bernardino County to explore the experiences of you adults in Extended Foster Care. Extended Foster Care is an extension of foster care services offered from age 18 to 21 as a result of the passing of Assembly Bill 12. This study focuses specifically on the experiences of young adults deemed “successful” based upon their enrollment in school, work status, and overall plans for their future. The data was collected through telephone and face-to-face interviews with young adults currently involved with Extended Foster Care in San Bernardino County.
The findings of this study indicated that successful young adults tend to demonstrate some level of resiliency and have an overall positive outlook, are self-motivated, have better relationships with their social workers, an overall good understanding of the program and services offered, stable supports, and all participants became involved in EFC immediately following regular foster care. Young adults also expressed a desire for more assistance in gaining work experience. The strengths of this study include the use of open ended questions and triangulation of analyzing data. Limitations of this study include participant self-selection bias and the briefness of the interview that may have not allowed for sufficient time for young adults to reflect intensely on their experiences.
Recommendations for future social work policy, practice, and research based on the findings of this study include extending foster care services beyond age twenty-one, the importance of social workers roles in young adult clients’ lives, and the need for continued, more intensive research.
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Massa, Nathaniel P. "Internationalisation of traditional, small and medium-sized family businesses : an absorptive capacity approach." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/3345/.
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This thesis investigates the internationalisation of Maltese small and medium-sized family businesses (SMFBs) engaged in more traditional economic activity. Despite family businesses dominating enterprise populations worldwide, and increasing policy awareness acknowledging their leading role in socio-economic development, research into the internationalisation of family businesses remains extremely limited. Addressing this gap, this study examines the internationalisation of these under-researched firms, investigating how their unique characteristics and circumstances impact and effect on internationalisation dynamics and processes. The overarching exploratory research question driving the central thrust of this study is: ‘What is the nature and extent of internationalisation among SMFBs in this context?’ In increasingly competitive globalised markets, understanding such dynamics is important at firm and national levels. Subsequently, given the established fundamental role of knowledge in internationalisation, this study seeks further understanding asking: ‘How do such SMFBs approach knowledge requirements associated with internationalisation, as proposed by the absorptive capacity (ACAP) approach?’ In adopting an ACAP approach, this research explores and examines how information and knowledge associated with internationalisation is acquired, assimilated and exploited. Given that hardly any research exists at the domain intersects which this thesis addresses, it synthesises and draws together research from the distinct fields of small firm internationalisation, family business, and emerging ACAP research. Seeking context-rich meanings, a qualitative, case-based approach involving eight SMFBs was adopted. Focus converged onto specific internationalisation events. First, in-depth analysis of the SMFBs’ outward internationalisation processes from first steps was undertaken – tracing SMFBs’ evolution, development and international activity over time. Secondly, adopting an ACAP approach and building on acquired insights guiding further investigation, an analytic framework was developed integrating internationalisation events with associated ACAP dynamics. The SMFBs’ internationalisation was found to be mainly influenced by the entrepreneur system, managers’ characteristics and volition, idiosyncratic circumstances and environmental dynamics. Contrasting with internationalisation process theories (IPT) traditionally attributed to this context, SMFBs were also observed internationalising from inception, or rapidly as ‘born again internationals’ at a mature stage. Despite size-related resource limitations, in instances owner-MDs creatively engaged in more committing modes and FDI – leapfrogging internationalisation stages. Such behaviour not being sufficiently explained or accommodated by IPT or INV perspectives, this thesis underlined importance in adopting more holistic approaches, integrating social and relational as well as resource perspectives in investigating complex phenomena associated with internationalisation. Novel in adopting an ACAP approach in this context, key findings converged on the crucial centrality of the founder / owner-MD and the vital role of social contacts and relationships in determining SMFB internationalisation and associated ACAP. A main contribution of this research inheres in its empirically derived insights and the development of a conceptual approach on these tacit core elements organically determining internationalisation, associated ACAP dynamics and capability in traditionally-oriented SMFBs. This departs from existing operationalisations which emphasise formal and structured knowledge processes within knowledge-intensive corporate environments – incompatible with this research’s context, notwithstanding ACAP’s universal relevance. Findings highlight the importance of delicately balancing management and family dynamics, a double-edged prime source of competitive advantage (or disadvantage) directly influencing both ACAP and internationalisation capability. This thesis concludes with a discussion of the implications for theory, management and policy.
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Levy, Theresa A. "An analysis of local district capacity in the implementation of Oregon's extended application collection of evidence graduation requirement." Thesis, Connect to title online (Scholars' Bank) Connect to title online (ProQuest), 2009. http://hdl.handle.net/1794/10228.
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Keller, Christine. "Community Connections Factors Related to Army Wives' Adaptation." Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/34472.
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When military members deploy or temporarily relocate, spouses are left behind to maintain not only their normal day-to-day activities, but also assume the responsibilities of the absent spouse. In cases such as these potentially stressful events, it is important to have adequate support networks within the community to assist individuals in sustaining a sense of personal well-being. The data source of the study is the 2001 Survey of Army Families IV. The survey focuses on randomly selected wives of active duty Army members (n=6451). The research model for this study includes wives' adaptation as the criterion variable, with community connections as independent variables and a set of contextual influence measures also considered as independent variables. Regression analysis for the entire sample indicated that wives with greater adaptation utilized more formal network resources. Among wives of officers, the most important predictors were volunteering and having a close confidant, whereas among wives of enlisted military members most important factors were participating with the Family Readiness Group and employment status.Master of Science
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Quaye, Daniel M., and mikewood@deakin edu au. "The impact of the extended family on microenterprise growth in Ghana: A case study of Accra." Deakin University, 1998. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20051123.122956.
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This study examines the extended family's impact on microenterprise growth at the individual level, where microenterprise operators have some control over constraints affecting their operations. Beyond the individual level, microenterprise operators have little control over constraints such as government policies and regulations, competition from import-substitution industries and exploitation by corrupt officials. Therefore, it is at the individual level that the extended family serves as a crucial parameter of microenterprise growth and the success with which MEs graduate from the informal sector into the mainstreams of small business. Within this domain, this author has examined the extended family and found that there is a need for policy makers and MED administrators to adopt a more culturally sensitive approach to microenterprise growth if the extended family is to be engaged as a partner in their efforts to support microenterprises as a source of income and employment generation,
A central question posed is why most writers on microenterprise activities in Ghana have neglected the extended family as a factor that should be considered in the design of microenterprise growth strategies and policies? The answer to this question was explored in the process of data gathering for this thesis and the results are presented here, especially in chapter 3 below. Suffice it to note here that this neglect has many roots, not least of which is the proclivity of mainstream economics, modern administration practice and the objectivity of double entry accounting based documentation procedures to focus on measurable growth in the formal sectors of the economy and structural constraints such as the lack of finance, lack of market demand, lack of access to technology and government regulations. Consequently, a noticeable trend among these writers is that they rightly advocate finance be made accessible to microenterprises, however, few question whether the finance is effectively used towards microenterprise growth. This issue is crucial in the face of evidence from this study which shows that finance accessed towards microenterprise growth is often put to other uses that negate growth thus keeping microenterprises within the bounds of the informal sector as against graduating out of the informal sector. As a result, these writers have neglected the intimate relations between the extended family and microenterprises, and most importantly, the constraint that the extended family inflicts on microenterprise growth at the individual level of activity. This study, by targeting the growth of the individual microenterprise in the socio-cultural context in which this growth must be achieved, has highlighted the constraint that the extended family does pose on MED. However, the study also shows that these constraints are important not because there is anything inherently wrong with the extended family, but because the socio-economic and policy environment is not consistent with the positive role that the extended family can and should play in the graduation of microenterprises from the informal to the formal sector of the economy in Ghana.
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Razali, Siti Katizah. "Women in educational management in Sarawak : a study of traditional and professional challenges." Thesis, University of Bristol, 1998. http://hdl.handle.net/1983/07df9f34-8dbb-4eb1-8e71-12c865c14a68.
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This exploratory study examined how women managers in education in Sarawak combine their traditional and professional roles and deal with potential role conflict. The study is set in the context of an increasing number of women managers in education in Sarawak and the issues this raises for their support, if they are to harmonise their roles and advance professionally. The aim of the study is to furnish policy makers at the national and state level with information to formulate a policy document which could be adopted in preparing a strategy for the advancement of women managers, taking into account their dual roles. Both quantitative and qualitative paradigms are employed to provide depth and breadth. The postal survey questionnaire was sent to all the 109 women in the target population: all women heads and deputies in schools, teacher training colleges and the State Education Department. There was a 91.7% response rate. Additionally, eight women managers were interviewed in-depth, together with seven spouses and three other senior women in education, who are influential nationally. The eight women managers also completed time-log diaries for a week. Respondents in the survey questionnaire included managers who, at one time, had rejected promotion. This enabled the perceptions of those who had experienced difficulties in relation to promotion to be analysed, as well as those who had not. Combining the quantitative and qualitative approaches meant that they complemented, supplemented and illuminated each other. The study did not aim, initially, to explore the cultural dimension but it emerged during the interviews that their specific cultural origins (Malay, Iban and Chinese) were a significant determinant of the women managers' perceptions of their dual roles. Indigenous culture was not found to be a barrier to advancement but the research has revealed that when studying women in educational management consideration of individual cultural contexts gives additional insights into their perceptions of their two roles. Interviews with the spouses revealed corresponding views to those of their wives pertaining to women's traditional roles; they also saw complementary roles in the partnership. The close support of the extended family is a significant factor in the study. For the women studied, the boundaries between their personal and professional roles were not clear-cut. Work invaded their personal lives and family needs were perceived as paramount when considering promotion. Values relating to caring and nurturing imbued their professional and personal lives. The different cultural and environmental experiences of the women managers contributed to their varied perceptions of role conflict. Many had developed coping strategies which reduced such conflict and supported their successful performance as workers, wives, mothers and daughters. Impediments to the advancement of women managers are identified and possible courses of future action suggested. Implications for policy makers at the Ministry of Education and State Education Department as well as for future research are highlighted
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Roberts, Kevin. "African-Virginian Extended Kin: The Prevalence of West African Family Forms among Slaves in Virginia, 1740-1870." Thesis, Virginia Tech, 1999. http://hdl.handle.net/10919/31780.
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Scholarship on slave families has focused on the nuclear family unit as the primary socializing institution among slaves. Such a paradigm ignores the extended family, which was the primary form of family organization among peoples in western and central Africa. By exploring slave trade data, I argue that 85% of slave imports to Virginia in the 18th century were from only four regions. Peoples from each region-the Igbo, the Akan, Bantu speakers from Angola and Congo, and the Mande from Senegambia-were marked by the prevalence of the extended family, the centrality of women, and flexible descent systems. I contend that these three cultural characteristics were transferred by slaves to Virginia.
Runaway slave advertisements from the Virginia Gazette show the cultural makeup of slaves in eighteenth-century Virginia. I use these advertisements to illustrate the prevalence of vast inter-plantation webs of kin that pervaded plantation, county, and even state boundaries. Plantation records, on the other hand, are useful for tracking the development of extended families on a single plantation. William Massie's plantation Pharsalia, located in Nelson County, Virginia, is the focus of my study of intra-plantation webs of kin. Finally, I examine the years after the Civil War to illustrate that even under freedom, former slaves resorted to their extended families for support and survival.
Master of Arts
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Hageman, Jurre. "The human HSP70/HSP40 chaperone family a study on its capacity to combat proteotoxic stress /." [S.l. : [Groningen : s.n.] ; University of Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn/.
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Mwema, Hadija Saidi. "Forensic identification of six of Tanzanian populations using the extended haplotype markers." Thesis, University of the Western Cape, 2011. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_2349_1325671867.
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The aim of the present study was to evaluate the power of discrimination and genetic (diversity) parameters in the Y chromosome extended haploytpe markers in populations of Tanzania for forensic and populations studies. Eleven Y chromosome extended haplotype markers were selected for this study, these includes Minimal haplotypes markers i.e. DYS19, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS389I/II and two additional markers DYS438 and DYS439. Six populations of Tanzania were investigated under this study. These populations were selected based on the language family categoriesNiger Congo (Kuria and Sukuma), Nilo Saharan (Luo and Maasai) and Afro Asiatic (Iraqw and Alagwa).
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Cook, Natalie E. "Aligning Cultural Responsiveness in Evaluation and Evaluation Capacity Building: A Needs Assessment with Family Support Programs." Thesis, Virginia Tech, 2016. http://hdl.handle.net/10919/64424.
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Family support programs serve vulnerable families by providing various forms of support, such as education, health services, financial assistance, and referrals to community resources. A major feature of evaluation involves assessing program effectiveness and learning from evaluation findings (Mertens and Wilson, 2012). Collaboration and cultural responsiveness are important topics in evaluation which remain largely distinct in the literature. However, evaluation capacity building provides a context for exploring possible intersections.
Data about seven programs were collected via semi-structured interviews and document analysis. This study revealed that the program leaders feel that their programs are unique, complex, and misunderstood. The findings also suggest that program leaders believe that evaluation is important for program improvement and funding. Although participants did not anticipate evaluation capacity building and did not readily express a desire to develop their own evaluation skills, participants from all seven programs enthusiastically expressed interest in evaluation capacity building once explained.
Although participants did not discuss cultural responsiveness as it relates to race, they expressed a need to overcome a community culture of reluctance to participate in programs and aversion to educational pursuits. Given the programs' shared population of interest, similar outcomes, and common challenges, evaluation capacity building in a group setting may give Roanoke family support program leaders the evaluation knowledge, skills, and peer support to engage in program evaluation that is both collaborative and culturally responsive.Master of Science in Life Sciences
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Obinwa, Ignatius M. C. "The Universal Church and a Wider Notion of the Domestic Church: Approaching Ecumenism from the African Extended Family System." Bulletin of Ecumenical Theology, 2011. http://digital.library.duq.edu/u?/bet,230.
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Skouris, Nicolas. "The LuxC reductase of the marine bacterium Photobacterium phosphoreum may be part of the aldehyde dehydrogenase extended family of enzymes /." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81441.
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The acyl-CoA reductase, LuxC, isolated from Photobacterium phosphoreum , has been found to have a low sequence identity to aldehyde dehydrogenases, particularly in the more conserved regions (i.e. motifs) containing the active site residues. Mutational studies on residues involved in cofactor binding and in catalysis conserved in both the LuxC enzyme and in Vibrio harveyi aldehyde dehydrogenase have shown that these residues may play similar roles as the effects of mutation on the kinetic parameters of the two enzymes were found to be very similar. Moreover, preliminary X-ray structural characterization of LuxC shows that its overall structure and fold is very similar to that of the V. harveyi aldehyde dehydrogenase. Both enzymes are able to bind their NAD(P)(H) cofactors in much the same way and the beta-sheet extension that is seen upon dimer formation in the V. harveyi enzyme is also seen in the P. phosphoreum enzyme. Given these results, and the fact that PpLuxC and Vh-ALDH have polypeptides of very similar size that can catalyze similar reactions, albeit in opposite directions, we are proposing that the acyl-CoA reductase of P. phosphoreum is part of the aldehyde dehydrogenase extended family, making it the first member of this family to preferentially catalyze the reduction of fatty acids to aldehydes rather than the oxidation of fatty aldehydes to acids. Finally, through the study of a critical glutamate residue of V. harveyi aldehyde dehydrogenase, we have provided direct evidence that this residue may be the critical determinant in deciding whether aldehyde oxidation or acid reduction is catalyzed preferentially.
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Ying, Dingge, and 应鼎阁. "Identification of shared extended haplotypes in both population-based studies of complex disease and family-based studies of Mendelian disorders." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/205837.
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Recent founder mutations may play important roles in complex diseases and Mendelian disorders. Detecting shared haplotypes of identity by descent (IBD) could facilitate discovery of these mutations. Several programs address this such as threshold-based methods on genetic distance and probabilistic model-based methods, but they are usually limited to only detecting pair-wise shared haplotypes and not providing a comparison between cases and controls.
In this study, a novel algorithm and a applied software package (HaploShare)is developed to detect extended haplotypes that are shared by multiple individuals, which also allows comparisons between cases and controls. A catalog of haplotypes is firstly generated from healthy controls from the same population and used for phasing genotypes in cases. By accounting for all possible haplotype pairs that could explain the genotypes for each individual in a given haplotype block and possible transitions between blocks, the effect of phase uncertainty on detection power is minimized. In cases, haplotypes shared by pairs are identified and used to detect sharing of these haplotypes by different pairs. A likelihood ratio of a shared haplotype due to IBD or chance is estimated for each extended haplotype. Controls are used similarly through many rounds of simulations to obtain an empirical null distribution of the largest likelihood ratios of shared haplotypes, to give statistical estimates of shared haplotypes detected in cases that may be associated with an underlying disease.
Series of tests were performed to investigate the performance of HaploShare. Simulations of shared haplotypes demonstrated that HaploShare has better power not only on the detection of pair-wise shared haplotypes but multiple shared haplotypes in most of the simulation scenarios, comparing with other four commonly used programs. False positive rate (FPR) and the false discovery rate (FDR) were also evaluated by statistical calculation. According to the result, both of the two values were extremely low (FPR = 6.28x10-6 , FDR = 0.006), indicating that very few randomly shared haplotypes can be wrongly reported as IBD by HaploShare.
HaploShare was also tested on real cases on population data and family linkage analysis. 14 out of 173 Hirschsprung's disease cases were reported by HaploShare of carrying a common haplotype of 250 kb in length, which was consistent with previous findings by direct genotyping and candidate approach. Another testing case is an affected family with 8 cases and 9 unaffected individuals. Disease linked region can be correctly identified by traditional methods if all the data and the entire pedigree were provided. HaploShare showed the ability to locate the shared region even when very limited cases are available, which is clearly beyond the detection power of traditional methods.
The results from empirical simulations and real case applications indicate that HaploShare could effectively make use of population genotype information to improve the power of detection of shared haplotypes. The method may extend the findings in human genetics of both complex and single gene diseases.published_or_final_version
Psychiatry
Doctoral
Doctor of Philosophy
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Galal, Ushma. "The statistical theory underlying human genetic linkage analysis based on quantitative data from extended families." Thesis, University of the Western Cape, 2010. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_2684_1361989724.
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Traditionally in human genetic linkage analysis, extended families were only used in the analysis of dichotomous traits, such as Disease/No Disease. For quantitative traits, analyses initially focused on data from family trios (for example, mother, father, and child) or sib-pairs. Recently however, there have been two very important developments in genetics: It became clear that if the disease status of several generations of a family is known and their genetic information is obtained, researchers can pinpoint which pieces of genetic material are linked to the disease or trait. It also became evident that if a trait is quantitative (numerical), as blood pressure or viral loads are, rather than dichotomous, one has much more power for the same sample size. This led to the
development of statistical mixed models which could incorporate all the features of the data, including the degree of relationship between each pair of family members. This is necessary because a parent-child pair definitely shares half their genetic material, whereas a pair of cousins share, on average, only an eighth. The statistical methods involved here have however been developed by geneticists, for their specific studies, so there does not seem to be a unified and general description of the theory underlying the methods. The aim of this dissertation is to explain in a unified and statistically comprehensive manner, the theory involved in the analysis of quantitative trait genetic data from extended families. The focus is on linkage analysis: what it is and what it aims to do.
There is a step-by-step build up to it, starting with an introduction to genetic epidemiology. This includes an explanation of the relevant genetic terminology. There is also an application section where an appropriate human genetic family dataset is analysed, illustrating the methods explained in the theory sections.
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PETEET, (MITCHELL) BRIDGETTE J. "GENDER AS A MODERATOR OF FAMILY DRUG INFLUENCE AND CHILD FUTURE DRUG RISK." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1112968034.
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Tsoroni, Agathi. "An extended investigation into the educational offers made by digital interactive exhibits the sustainability of these approaches, and their capacity to provide novel experience." Thesis, Birmingham City University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.496504.
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The last two decades have seen the widespread introduction of digital interactive exhibits in galleries and museums. This has brought with it certain expectations of the pedagogical offer of these institutions: digital interactive exhibits are seen as being more democratic than their analogue counterparts; and are expected to provide more Open-ended pedagogy, as they are understood to be aligned with a postmodern understanding of the role of the viewer/learner.
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Watson, Sabrina Blount. "Correlations of Race, Ethnicity, and Family Relations on the Developmental Outcomes of Youth Raised in Single Mother Headed Households." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/3075.
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Despite known risk factors associated with families headed by single mothers such as delinquency, substance abuse, and early unprotected sex, researchers have rarely focused on how family relations positively shape the developmental trajectories of youth living in nontraditional families. The purpose of this correlational study was to examine the relationship between the independent variables of ethnicity, parent-child relationship, and family interaction (including the relationship with important non-parental adults) and the dependent variables of developmental outcomes (social and emotional competence) for youth living in families headed by single mothers. The associations were investigated using data collected from the Project on Human Development in Chicago Neighborhoods, a longitudinal cohort study. The relationships between variables were analyzed using a descriptive statistics method. The results of the study indicated no race-related differences in a child's closeness to mother in single-mother families. A significant positive correlation showed a difference in closeness to family members across ethnic groups, by age. Multiple regression analysis was employed to determine if there were statistically significant differences between closeness to the mother or family members, and the outcomes. The findings indicated that closeness to family was positively correlated to emotional outcomes for youth, and a significant positive correlation was found between family interaction and social outcomes. These results may have implications for positive social change by providing public health practitioners with strategies to support positive youth development, altering the future of youth, families, and society which will ultimately benefit from a stronger population of emotionally and socially competent young adults.
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Cooper, Kenneth Paul. "The faith community as extended family, the influence of shared spiritual values as experienced by Baha'i families in the Cowichan Valley." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ32659.pdf.
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Green, Marcus. "Social networks and residential mobility in later life : the effects of moving on social network supportive capacity amongst older people in the UK." Thesis, University of Southampton, 2014. https://eprints.soton.ac.uk/368007/.
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This is an interdisciplinary PhD research project, spanning the ESRC Centre for Population Change and the Centre for Research on Ageing. Using British Household Panel Survey data, the thesis aims to prove that undertaking a residential move changes the supportive capacity of one’s social network in later life. The study first investigates the determinants of moving home in later life. It then conceptualises and constructs the social networks of older people in the UK, considering key attributes such as network size, frequency, proximity and functions and examines the effects of moving home on these measures. The analysis finds that the incidence of residential mobility is associated with, amongst other things, becoming widowed and experiencing a negative change in health or financial circumstance. Furthermore older people are likely to experience disruption to the supportive capacity of their companionship and community networks following a move. This research has important implications for policy as any damaging effects on an older person’s informal support network may have consequences for their health outcomes and in turn lead to an increased dependence on formal health and social care services at the places to which they move.
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Silva, Graça Andrade Mira Antunes da. "Estrutura familiar e social em Torres Vedras no início do século XX. Uma perspectiva histórica comparada." Master's thesis, Universidade de Évora, 2013. http://hdl.handle.net/10174/16341.
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Estrutura Familiar e Social em Torres Vedras no Início do Século XX. Uma Perspetiva Histórica Comparada
O objetivo central deste estudo é a caraterização de um modelo de estrutura familiar cujo ponto de partida será o estabelecimento do modelo de estrutura familiar e social de Torres Vedras, tendo como referência o modelo de transição demográfica e social na Europa contemporânea na passagem do séc. XIX para o séc. XX.
A unidade de análise tem por base um universo restrito: três paróquias do concelho de Torres Vedras: Santa Maria e S. Miguel e S. Pedro e S. Tiago, de caráter “urbano”, mas fortemente marcadas pelo peso rural e uma paróquia do litoral ocidental do concelho: S. Mamede da Ventosa, na qual se verificou um crescimento populacional de grande relevo no período em estudo.
Apoiados em estudos europeus interdisciplinares sobre a formação de uma sociedade europeia procuraremos situar-nos nos debates sobre a difusão da família europeia e a configuração social das sociedades europeias no dealbar do séc. XX; ABSTRACT: Social and Family Structure in Torres Vedras at the Beginning of the Twentieth Century. A Comparative Historical Perspective
The principal aim of this study is the characterization of a model of family structure.
I will begin by characterizing the model of the social and family structure in Torres Vedras, and I will also focus on the pattern of the demographic and social change in Europe at the turn of the nineteenth century.
The unit of analysis is based on a restricted universe: three parishes from the municipality of Torres Vedras: Santa Maria and S. Miguel and S. Pedro and S. Tiago, both urban, but also marked by rurality. The third parish is located in the western part of the municipality, S. Mamede and witnessed a major demographic growth during the period under study.
Based on interdisciplinary European studies about the formation of a European society, I will attempt to position myself in the debate on the propagation of the European family and on the social structure of the European societies at the dawn of the twentieth century.
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Quagraine, Victor Kwesi. "New strategies to improve the management capacity of contractors for labor-based methods in road rehabilitation in Ghana." Diss., Virginia Tech, 2007. http://hdl.handle.net/10919/26799.
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Ghana, like many African countries, is plagued with unemployment, poverty and annual trade deficits. Unemployment and poverty have led to a socio-economic breakdown. They are believed to be among the causes that led to the 1994 Rwanda genocide. Despite the abundance of an unemployed labor force, Ghana continues to depend on imported equipment, costing $174 million annually for its earthmoving and construction activities. In 1986, the Government of Ghana, the World Bank, the International Labor Organization and the United Nations Development Program introduced labor-based road rehabilitation program in Ghana to help create more jobs and reduce the high unemployment and poverty incidence. The program has not been patronized due to the casual labor usage and labor organizational and management problems.
This research formulates the Family-Based Labor Management (FBLM) concept (also referred to as the HPWT-FBLM concept) by incorporating High Performance Work Team (HPWT), the Ghana Family System, and Roles and Responsibilities Matrix (RRM) concepts to make the program more attractive to labor and management. The FBLM concept would equip local contractors with the managerial skills to increase average monthly production from 1.33km to between 4km and 6km gaining competitive advantage over the 3.07km monthly production of the equipment-intensive contractor. Since the HPWT-FBLM concept has not been used, the related concepts HPWT and RRM concepts are used to validate the newly formulated recruitment, training, work method, communication and reward strategies. When adopted, the HPWT-FBLM concept would annually invest 10% of the $174 million for five years and yield employment increase of 23,000-34,000 the first year, growing to a total of 116,000-170,000 in five years. This concept will help reduce import deficit, conserve foreign exchange, and develop a pool of skilled workers and managers in Ghana. It has the potential of boosting the Ghanaian manufacturing industry for making hand-tools in lieu of purchasing imported equipment. The HPWT-FBLM concept can be adopted by the agriculture and building construction and other industries in Ghana that use large supplies of unskilled and semi-skilled labor.Ph. D.
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Hynds, Aaron Michael. "The Composer's Guide to the Tuba: Creating a New Resource on the Capabilities of the Tuba Family." Bowling Green State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1558255903237631.
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Fakhiri, Julia [Verfasser], and Christof von [Akademischer Betreuer] Kalle. "With small viruses come giant responsibilities - Next-generation parvoviral vectors for human gene therapy with extended packaging capacity and enhanced safety profile / Julia Fakhiri ; Betreuer: Christof von Kalle." Heidelberg : Universitätsbibliothek Heidelberg, 2019. http://d-nb.info/1199196088/34.
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Senia, Ranyouri Hines. "Current Capacity Building Needs of Occupational Therapists Related to Older Driver Screening, Assessment, and Intervention." ScholarWorks, 2015. https://scholarworks.waldenu.edu/dissertations/380.
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Older adult safe driving is a growing public health issue; however, the skill set of occupational therapists that provide services to these older clients is unclear. The extent to which occupational therapists possess the skills to evaluate an elderly person's ability to operate safely an automobile is unclear. Therefore, the purpose of this quantitative, cross-sectional survey was to determine the current capacity building needs of occupational therapists (OT) related to older driver screening, assessment, and intervention. The ecology of human performance framework was the theoretical base of the study. The independent variables were the OTs' training related to older drivers, the OTs' current driving-related professional activities, and the OTs' continuing education interests. The dependent variable was the reported levels of competence in screening, assessment, and intervention, and the covariates were years of experience, level of education, practice setting, gender, and regional location. The survey was disseminated through technological channels of social media and e-mail. The responses from 61 participants were used for analysis. In a descriptive analysis, OTs felt that addressing driving through screening, assessment, and intervention is somewhat important, that currently OTs seldom address driving, and OTs are not very likely to take continuing education courses related to driving in the next 2 to 3 years. In addition, a linear regression analysis determined a relationship between an OT's actual practice and perceived competence. A positive social change of this study emphasized a better understanding of OT's ability to provide driver rehabilitation services to a growing aging population, which in turn promotes safety on the roads.