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1

Bondarenko, G. A., I. A. Solovyova, and T. I. Trukhina. "Morphological features of capsules of trichinella larvae in wild animals of the amur region." International Journal of Veterinary Medicine, no. 1 (June 16, 2023): 57–63. http://dx.doi.org/10.52419/issn2072-2419.2023.1.57.

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The problem of trichinosis on the territory of the Far East has a pronounced natural focal character with the predominant circulation of the causative agent of trichinosis in wild animals. The main species circulating in the Amur Region is the capsule- forming species T. spiralis. The ability to form capsules is one of the biological features of Trichinella larvae and a necessary component of the process of their survival. The thickness of the walls of the capsule gradually increases while the larva and intracapsular muscle sarcoplasm with nuclei remain alive. At the same time, the morphologic
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Ramli, Nur Amalina, Nurul Natasya Amira Kamaluddin, and Fatmawati Adam. "Mechanical, Structural and Physical Properties of Carrageenan-Gum Arabic Biocomposite Film for Hard Capsule Application." Solid State Phenomena 340 (December 23, 2022): 11–18. http://dx.doi.org/10.4028/p-c2wejl.

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The hard capsule market growth is mainly driven by the demand for gelatin capsules made of animals. Plant-based hard capsules, such as hydroxypropyl methylcellulose are currently in high demand for drug delivery, but the manufacturing process is costly with limited reagent supply. As an alternative, carrageenan from seaweed was used as a film-forming agent in this work. Carrageenan film possesses low mechanical strength, thus gum Arabic is incorporated to strengthen the biocomposite film. The films and hard capsules were produced with different concentrations of gum Arabic, ranging from 0 to 2
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BALILASHAKI, Khosro, Roohangiz NADERI, Saikat GANTAIT, and Maryam VAHEDI. "Asymbiotic Germination of Phalaenopsis cv. ‘Dublin’ Seeds in Relation to Pollination Months and Nutrient Media." Notulae Scientia Biologicae 7, no. 3 (2015): 330–33. http://dx.doi.org/10.15835/nsb739574.

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Orchids are one of the most popular flowers in the world and Phalaenopsis genus shares maximum sales in global floral industry among them. Successful pollination, followed by capsule formation and in vitro seed germination, is a powerful tool for mass propagation of orchids. In the present study, flowers of Phalaenopsis cv. ‘Dublin’ were self-pollinated artificially during the months of November, December, January, February, March and April. The influence of pollination month over capsule formation was assessed and it was observed that pollination during December resulted as maximum with 86% c
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Pyar, Hassan, and Kok-Khiang Peh. "Enteric coating of granules containing the probiotic Lactobacillus acidophilus." Acta Pharmaceutica 64, no. 2 (2014): 247–56. http://dx.doi.org/10.2478/acph-2014-0011.

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Abstract In the present study, a capsule formulation composed of enteric coated granules of Lactobacillus acidophilus ATCC 4962 was developed using Eudragit L30D-55 as enteric polymer. Optimization of the capsule formulation was achieved with a maximum viable cell count after 2 h of incubation in acid medium and disintegration time of 1 h in buffer pH 6.8. The amount of Eudragit L30D-55 in the capsules correlated with gastric juice resistance. The best protective qualities against artificial gastric juice were observed when capsules were prepared from granules composed of L. acidophilus, corn
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Sousa-Baena, Mariane S., and Nanuza L. De Menezes. "Comparative developmental anatomy of ovary and fruit in Brazilian Velloziaceae." Botanical Journal of the Linnean Society 191, no. 2 (2019): 236–60. http://dx.doi.org/10.1093/botlinnean/boz040.

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Abstract Morpho-anatomical studies of fruits are scarce in monocotyledons and particularly for the Brazilian species of Velloziaceae, a small family of monocots characteristic of the campo rupestre vegetation of Brazil. The main fruit types found in Velloziaceae are poricidal and loculicidal capsules, but capsule morphology is variable, which has led to discrepancies regarding fruit descriptions and terminology. In this study, we aimed to analyse fruit development in Brazilian Velloziaceae to obtain a better understanding of capsule dehiscence and to elucidate and describe in detail the fruit
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Shchukin, V. M., N. E. Kuz’mina, O. A. Matveeva, Yu N. Shvetsova, and E. S. Zhigilei. "Determination of Elemental Impurities in Gelatine Capsules by Inductively Coupled Plasma Mass Spectrometry." Safety and Risk of Pharmacotherapy 12, no. 2 (2024): 230–40. http://dx.doi.org/10.30895/2312-7821-2024-12-2-230-240.

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INTRODUCTION. Gelatine capsules are an essential dosage form used for many medicinal products. Gelatine capsules are subject to quality control in accordance with the requirements of the general monograph on capsules of the State Pharmacopoeia of the Russian Federation. This monograph does not standardise the content of elemental impurities, as these impurities are controlled at the raw material level. However, the equipment and excipients used in the production of gelatine capsule shells may be additional sources of impurities. Preliminary screening for chemical elements will help to assess t
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7

Abd, Hadi, Amir Saeed, Andrej Weintraub, and Gunnar Sandström. "Vibrio cholerae O139 requires neither capsule nor LPS O side chain to grow inside Acanthamoeba castellanii." Journal of Medical Microbiology 58, no. 1 (2009): 125–31. http://dx.doi.org/10.1099/jmm.0.004721-0.

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Vibrio cholerae, the causative agent of cholera, has the ability to grow and survive in the aquatic free-living amoeba Acanthamoeba castellanii. The aim of the present study was to examine the ability of the clinical isolate V. cholerae O139 MO10 to grow in A. castellanii and to determine the effect of the bacterial capsule and LPS O side chain on intracellular growth. Results from co-cultivation, viable counts, a gentamicin assay, electron microscopy and statistical analysis showed that the association of V. cholerae O139 MO10 with A. castellanii did not inhibit growth of the amoeba, and enha
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8

Nebel, RL, R. Vishwanath, WH McMillan, and RG Saacke. "Microencapsulation of bovine spermatozoa for use in artificial insemination: a review." Reproduction, Fertility and Development 5, no. 6 (1993): 701. http://dx.doi.org/10.1071/rd9930701.

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A technique for microencapsulation of bovine spermatozoa has been developed with minimal spermatozoal injury and thus of potential use in artificial insemination. The polymers poly-l-lysine, polyvinylamine and protamine sulfate have proven best for membranes. Encapsulation has been successful with capsules ranging in size from 0.75 to 1.5 mm, and with sperm concentrations from 45 to 180 x 10(6) cells mL-1. Successful extenders include CUE, CAPROGEN, and egg yolk-citrate-glycerol (maximum 10% v/v egg yolk for normal capsular shape). Capsule fragility (ability to rupture under ageing and physica
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9

Negrini, D., C. Gonano, M. Del Fabbro, and G. Miserocchi. "Transperitoneal fluid dynamics in rabbit liver." Journal of Applied Physiology 69, no. 2 (1990): 625–29. http://dx.doi.org/10.1152/jappl.1990.69.2.625.

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The peritoneal cavity of 18 anesthetized spontaneously breathing supine rabbits was opened through a midline section. One or two hollow capsules (surface area 0.8 cm2) were glued to the exposed liver surface, filled with whole or 25% diluted plasma, and connected to a transducer and a graduated pipette. Various hydraulic pressures (Pcap) were set in the capsule; at each Pcap the liquid flow per unit surface area (V/S) between the Disse's interstitial space and the capsule was measured from the rate of liquid displacement in the pipette. The slope of the V/S vs. Pcap linear regression was utili
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10

Zuppardo, Amy B., and Ronald J. Siebeling. "An Epimerase Gene Essential for Capsule Synthesis in Vibrio vulnificus." Infection and Immunity 66, no. 6 (1998): 2601–6. http://dx.doi.org/10.1128/iai.66.6.2601-2606.1998.

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ABSTRACT The extracellular capsule polysaccharide (CPS) of Vibrio vulnificus is a primary virulence factor which allows survival of the bacteria in the human host. To study the genes involved in expression of the capsule, we generated mutants that lost the ability to produce CPS following the insertion of a minitransposon into the genome of an encapsulated, clinical strain of V. vulnificus. A genomic region, from one nonencapsulated mutant, containing the transposon and flanking V. vulnificus DNA was cloned, and a probe complementary to the chromosomal DNA immediately adjacent to the transposo
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11

Shakyawal, Chanchal, Manju Singh, and Rishabh Shukla. "Determination of Genetic Diversity in Sesame (Sesamum indicum L.)." Journal of Experimental Agriculture International 46, no. 10 (2024): 136–41. http://dx.doi.org/10.9734/jeai/2024/v46i102932.

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Aim: To assess the degree of genetic divergence (D2 statistics) among sesame genotypes with respect to various traits. Study Design: The present experiment evaluated in the Randomized Block Design (RBD) with three replications. Place and Duration of Study: Experiment was carried out during Rabi, 2023 at Niger Research Station, NAU, Vanarasi. Methodology: To evaluate the genetic diversity among 30 sesame genotypes, Mahalanobis D² Statistics was utilized. The genotypes were classified into six distinct clusters using Tocher’s method, revealing substantial diversity. Results: Cluster I contained
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12

Fuller, John C., Rick L. Sharp, Hector F. Angus, Paul Y. Khoo та John A. Rathmacher. "Comparison of availability and plasma clearance rates of β-hydroxy-β-methylbutyrate delivery in the free acid and calcium salt forms". British Journal of Nutrition 114, № 9 (2015): 1403–9. http://dx.doi.org/10.1017/s0007114515003050.

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Abstractβ-Hydroxy-β-methylbutyrate (HMB), a leucine metabolite, has long been supplemented as a Ca salt (Ca-HMB) to increase strength and performance gains with exercise and to reduce recovery time. Recently, the free acid form of HMB (HMB-FA) has become commercially available in capsule form (gelcap). The current study was conducted to compare the bioavailability of HMB using the two commercially available capsule forms of HMB-FA and Ca-HMB. We also compared the pharmacokinetics of each form when administered mixed in water. Ten human subjects (five male and five female) were studied in a ran
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13

Smith, Amy B., and Ronald J. Siebeling. "Identification of Genetic Loci Required for Capsular Expression in Vibrio vulnificus." Infection and Immunity 71, no. 3 (2003): 1091–97. http://dx.doi.org/10.1128/iai.71.3.1091-1097.2003.

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ABSTRACT Transposon mutagenesis of an encapsulated, virulent strain of Vibrio vulnificus 1003(O) led to the identification of four genetic regions that are essential to capsular polysaccharide (CPS) expression and virulence. Of the four regions, three are believed to be part of a capsule gene locus comprised of biosynthesis, polymerization, and transport genes clustered on a single chromosomal fragment. Genes indicating a Wzy-dependent system of polymerization and transmembrane export are present, suggesting that the CPS of V. vulnificus is lipid linked. The fourth region, while it contains a
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14

Al-idee, T., H. Habbal, F. Karabet, and I. Alghoraibi. "Comparison Study between Cherry and Arabic Gums in Preparation and Characterization of Orange Peel Extract Nanocapsules." Journal of Nanomaterials 2022 (January 18, 2022): 1–11. http://dx.doi.org/10.1155/2022/7721983.

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This study was aimed at determining the potential use of cherry gum (CG) and chitosan (CS) as wall materials, to encapsulate an orange peel extract (PE) via the ionic gelation method and compare its efficiency with that of Arabic gum (AG). Different ratios of chitosan to gum (1 : 1, 1 : 2, and 1 : 3, v / v ) and CS to PE (1 : 0.5, 1 : 1, and 1 : 1.5, v / v ) were studied to evaluate the nanocapsule properties. The results showed that the capsules entrapping the PE were successfully created with an encapsulation efficiency (EE %) of more than 80% via the ionic gelation method. The ratio of chit
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15

Lonca, Nelly, Fabienne Maillard, Géraldine Leguelinel, Tahmer Sharkawi, and Ian Soulairol. "Validation of an HPLC Assay Method for Routine QC Testing and Stability Study of Compounded Low-Dose Capsules of Acetylsalicylic Acid." Pharmaceutical Technology in Hospital Pharmacy 3, no. 4 (2018): 199–206. http://dx.doi.org/10.1515/pthp-2018-0022.

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Abstract Background The intolerance to Acetylsalicylic Acid (ASA) can be detected by conducting oral provocation testing (OPT), which is to gradually introduce low doses of ASA. To perform this test, hospital pharmacies compound small batches of different low-dosage ASA capsules. This work aims to validate a method for fast HPLC-UV assay that allows routine quality control and physicochemical stability studies of capsules. Methods The chromatographic separation is performed using a C18 column Kinetex (100 A, 50×4.6 mm, 2.6 µm) equipped with a precolumn C18. Separation is achieved using a mobil
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16

Pezzoli, A., N. Fusetti, V. Cifalà, L. Simone, A. Zelante, and S. Boccia. "V.01.8 CAPSULE ENDOSCOPY DIAGNOSIS OF INTESTINAL TAENIA." Digestive and Liver Disease 46 (March 2014): S49. http://dx.doi.org/10.1016/s1590-8658(14)60138-9.

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17

Ni'mah, Yatim Lailun, Wemma Devega, Ita Ulfin, and Harmami Harmami. "Synthesis of Capsule Film from Water-Soluble Chitosan by Adding Sodium Lauryl Sulfate." Asian Journal of Chemistry 32, no. 3 (2020): 634–40. http://dx.doi.org/10.14233/ajchem.2020.21582.

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Mixtures comprising water-soluble chitosan (WSC), agar and different concentrations of sodium lauryl sulphate (SLS) were used to synthesize capsule films. The concentration of agar was fixed at 0.02 %, whereas the concentration (v/v) of SLS varied (0, 0.02, 0.04, 0.06 and 0.08 %). Shrimp shell waste was subjected to demineralization, deproteination and deacetylation to obtain chitosan. The chitosan thus obtained was depolymerized to produce water-soluble chitosan (WSC). Fourier-Transform infrared (FTIR) baseline method was used for calculating the degree of deacetylation of chitosan. FTIR spec
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18

Koshorek, Gail, Vartika Parashar, Thomas Roth, and Timothy Roehrs. "0462 Baseline Sleep Disturbance and Inability to Discontinue Chronic Hypnotic Use." Sleep 45, Supplement_1 (2022): A204—A205. http://dx.doi.org/10.1093/sleep/zsac079.459.

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Abstract Introduction Clinicians prescribing hypnotics remain concerned regarding the inability to discontinue hypnotics after chronic use, which has never been directly tested in a controlled prospective study using self-administration choice methodology. This study reports on difficulty discontinuing medication as a function of basal sleep disturbance in insomnia subjects instructed to stop taking their study medication after 6 months of nightly use. Methods DSM-V diagnosed insomnia subjects, aged 23-61 yrs, (n=39, 34 females), with no other sleep disorders, unstable medical or psychiatric d
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19

Swapna, B., Srikanth Thippani, D. Padmaja, and S. Srinivas Nayak. "Genetic Diversity for Yield and Yield Contributing Characters in Sesame (Sesamum indicum L.)." International Journal of Environment and Climate Change 13, no. 8 (2023): 1717–25. http://dx.doi.org/10.9734/ijecc/2023/v13i82124.

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In the present investigation, At RARS, Jagtial, 68 genotypes, including three checks were evaluated for genetic diversity for selection of diverse parents. Divergence studies through D2 statistic indicated the presence of substantial diversity by forming large number of clusters with wide range of inter-cluster distance.The 68 genotypes were distributed into eight clusters based on the D2 values. Among the eight clusters, cluster I was the largest comprising of 30 genotypes followed by cluster II with 22 genotypes and Cluster III and V with six genotypes in each cluster remaining clusters IV,
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20

Roth, T., G. Koshorek, J. Verkler, and T. Roehrs. "0494 Ability to Discontinue Chronic Hypnotic Use: An Update." Sleep 43, Supplement_1 (2020): A189. http://dx.doi.org/10.1093/sleep/zsaa056.491.

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Abstract Introduction Physicians prescribing hypnotics remain concerned regarding patient’s inability to discontinue hypnotics after chronic use. That concern has never been directly tested in a controlled prospective study using self-administration choice procedures. This is an update on results from an on-going “blinded” clinical trial in which insomnia subjects are instructed to stop taking their study medication after 6 months of nightly use. Methods DSM-V diagnosed insomnia subjects, aged 23-61 yrs, (n=31, 26 females), with disturbed sleep (i.e., polysomnographic sleep efficiency of ≤85%)
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21

Rukundo, Olivier, Marius Pedersen, and Øistein Hovde. "Advanced Image Enhancement Method for Distant Vessels and Structures in Capsule Endoscopy." Computational and Mathematical Methods in Medicine 2017 (2017): 1–13. http://dx.doi.org/10.1155/2017/9813165.

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This paper proposes an advanced method for contrast enhancement of capsule endoscopic images, with the main objective to obtain sufficient information about the vessels and structures in more distant (or darker) parts of capsule endoscopic images. The proposed method (PM) combines two algorithms for the enhancement of darker and brighter areas of capsule endoscopic images, respectively. The half-unit weighted-bilinear algorithm (HWB) proposed in our previous work is used to enhance darker areas according to the darker map content of its HSV’s component V. Enhancement of brighter areas is achie
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22

Joseph, Lavin A., and Anita C. Wright. "Expression of Vibrio vulnificus Capsular Polysaccharide Inhibits Biofilm Formation." Journal of Bacteriology 186, no. 3 (2004): 889–93. http://dx.doi.org/10.1128/jb.186.3.889-893.2004.

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ABSTRACT Vibrio vulnificus is a human pathogen that produces lethal septicemia in susceptible persons, and the primary virulence factor for this organism is capsular polysaccharide (CPS). The role of the capsule in V. vulnificus biofilms was examined under a variety of conditions, by using either defined CPS mutants or spontaneous CPS expression phase variants derived from multiple strains. CPS expression was shown to inhibit attachment and biofilm formation, which contrasted with other studies describing polysaccharides as integral to biofilms in related species.
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23

Anderson, James M., Thomas M. Hering, A. Lee Ansel, and John M. Johnson. "Nosocomial Graft Fragmentation and Healing Response of an ePTFE Angioaccess Graft." Journal of Biomedical Materials Research 21, S2 (1987): 153–62. http://dx.doi.org/10.1002/j.1097-4636.1987.tb00015.x.

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This investigation was directed toward the tissue reaction and wound healing response of an ePTFE prosthesis implanted in a human subject as an arteriovenous fistulae for over 7 years. Due to the frequent puncture of the prosthesis for hemodialysis access, the pattern of healing is markedly different from that normally observed in ePTFE grafts in humans. The ePTFE graft material of the AV fistula was completely incorporated in fibrous tissue with prominent pseudointima formation (inner capsule), fibrous tissue within the graft and a well‐adhered periadventitial layer (outer capsule). In the po
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Patankar-Jain, Kalpana, Parag Gadkari, and Pushkar Pradhan. "Rapid, simple and validated reverse phase method for analysis of glimepiride from capsules." GSC Biological and Pharmaceutical Sciences 5, no. 3 (2018): 043–45. https://doi.org/10.5281/zenodo.4305029.

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Glimepiride, a blood sugar controlling molecule have been analyzed from a marketed capsule consisting of glimepiride and pioglitazone using a reversed phase isocratic method. The method was developed on 150 mm × 4.6 mm, 5 µ C18 column. The mobile phase consisted of sodium dihydrogen o-phosphate pH 6.0: acetonitrile (60:40 v/v). The compounds gave a good UV response at 220 nm, hence the detection wavelength. The method was found to be highly specific for glimepiride in presence of Pioglitazone and other constituents of the capsule. The developed method is simple, precise, robust and
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Hà Thị Tâm Tiến, Phạm Thanh Loan, Hoàng Thị Lệ Thu, Nguyễn Thị Hà Phương, Nguyễn Quang Trung, and Nguyễn Văn Huy. "RESEARCH ON PREPARING HARD CAPSULES TO SUPPORT THE PREVENTION OF BLOOD LIPID DISORDERS FROM MEDICINAL HERBS." Tạp chí Khoa học và Công nghệ Trường Đại học Hùng Vương 37, no. 4 (2024): 110–20. https://doi.org/10.59775/1859-3968.236.

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Blood lipid metabolism disorder is related to the excess of fat in the blood, mainly caused by an uncontrolled diet and a sedentary lifestyle, causing atherosclerosis and embolism. The hard capsule to help prevent lipid metabolism disorder is prepared from the traditional medicine remedy Ban ha bach truat thien ma thang including 7 medicinal herbs Ban ha che, Thien ma, Tran bi, Bach truat, licorice, Poria cocos and Hawthorn fruit. The remedy has been recognized by the Ministry of Health to enhance the effect of the medicine. The study aims to develop a formula for preparing dry herbal extract
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26

He, Hongjun, Xueting Zhang та Yan Sheng. "Enteric-coated capsule containing β-galactosidase-loaded polylactic acid nanocapsules: enzyme stability and milk lactose hydrolysis under simulated gastrointestinal conditions". Journal of Dairy Research 81, № 4 (2014): 479–84. http://dx.doi.org/10.1017/s0022029914000491.

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In order to protect peroral β-galactosidase from being degraded and hydrolyse milk lactose efficiently in the environments of gastrointestinal tract, a double-capsule delivery system composed of enteric-coated capsule and polylactic acid (PLA) nanocapsules (NCs) was developed for encapsulation of β-galactosidase. β-galactosidase-loaded PLA NCs in the size range of 100–200 nm were prepared by a modified w1/o/w2technique. During the encapsulation process, dichloromethane/ethyl acetate (1 : 1, v/v) as the solvent composition, high-pressure homogenisation (150 bar, 3 min) as the second emulsificat
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Todd, Joshua J., Emeir M. McSorley, L. Kirsty Pourshahidi, et al. "Vitamin D3supplementation in healthy adults: a comparison between capsule and oral spray solution as a method of delivery in a wintertime, randomised, open-label, cross-over study." British Journal of Nutrition 116, no. 8 (2016): 1402–8. http://dx.doi.org/10.1017/s0007114516003470.

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AbstractVitamin D is typically supplied in capsule form, both in trials and in clinical practice. However, little is known regarding the efficacy of vitamin D administered via oral sprays – a method that primarily bypasses the gastrointestinal absorption route. This study aimed to compare the efficacy of vitamin D3liquid capsules and oral spray solution in increasing wintertime total 25-hydroxyvitamin D (25(OH)D) concentrations. In this randomised, open-label, cross-over trial, healthy adults (n22) received 3000 IU (75 µg) vitamin D3daily for 4 weeks in either capsule or oral spray form. Follo
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28

Sasipriya, S., K. Parimala, M. Balram, and K. B. Eswari. "Assessment of Genetic Diversity in Sesame (Sesamum indicum L.) for Yield and its Components." International Journal of Bio-resource and Stress Management 14, Mar, 3 (2023): 443–49. http://dx.doi.org/10.23910/1.2022.3231a.

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A field experiment was conducted to assess the diversity among sesame genotypes for yield and yield component traits during late kharif, 2017 (August-November) at Seed Research and Technology Centre, Rajendranagar, Hyderabad, Telangana State, India. Genetic diversity among the genotypes were estimated based on the data recorded for eight yield and yield attributing characters in 51 genotypes using Mahalanobis’s D2 statistics. The percent contribution of characters towards divergence showed that the character days to 50% flowering contributed maximum followed by seed yield plant-1, capsule leng
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29

Nemeti, Irina. "Seal Boxes from Potaissa." Studia Universitatis Babeș-Bolyai Historia 65, no. 1 (2021): 107–22. http://dx.doi.org/10.24193/subbhist.2020.1.07.

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"Abstract: The publication of a previously unpublished seal box discovered in Potaissa supports the reopening of the “dossier” of such items found both in the fort of the V Macedonica Legion and the city. One current knows of 10 artifacts in this category. Together with the other known writing implements, seal boxes complete our current knowledge regarding the use of writing and implicitly literacy in provincial society. Key-words: seal box; writing; Potaissa. Rezumat: Publicarea unei capsule de sigiliu inedite descoperită la Potaissa, a permis reluarea „dosarului” acestui tip de obiecte prove
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Ramya, Paka, Medidi Srinivas, and Bula Udaya Kumari. "Development of a Validated RP-HPLC/UV Method for the Quantitative Determination of Tyrosine Kinase RET Inhibitor: Selpercatinib in Capsule Formulation." Journal of Drug Delivery and Therapeutics 14, no. 7 (2024): 57–63. http://dx.doi.org/10.22270/jddt.v14i7.6702.

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A validated RP-HPLC/UV method was developed to estimate the selpercatinib in capsules. The wavelength chosen for detection was at 248 nm. The RP-HPLC separation was carried out using a Hypersil ODS C18 column (250×4.6 mm, 5 μm) with a mobile phase consisting of 0.2% TFA (pH 6.5) and acetonitrile in a ratio of 70:30 v/v. The flow rate was set at 1 ml/min. The retention time for selpercatinib was determined to be 3.012 min. Linearity was detected within the concentration range of 2.5-15 μg/mL for selpercatinib. The approach has been confirmed to be linear, accurate, precise, robust, and has esta
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31

Dighade, N. R., S. P. Padmane, and A. V. Kasture. "A VALIDATED RP-HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF PANTOPRAZOLE AND CINITAPRIDE IN A PHARMACEUTICAL FORMULATION." INDIAN DRUGS 51, no. 01 (2014): 27–33. http://dx.doi.org/10.53879/id.51.01.p0027.

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The study describes a validated stability indicating reverse- phase HPLC method for the simultaneous estimation of pantoprazole and cinitapride in capsule formulation. The proposed RP-HPLC method utilizes an Eclipse XDB C18 Column (150 × 4.6 mm i.d., 5μm), optimum mobile phase consisting of 10 mM phosphate buffer: acetonitrile: THF in the ratio of 64:36:0.5 V/V (pH 3.5) V/V, effluent flow rate 1 mL/min and UV detection wavelength of 266 nm. The selected chromatographic conditions were found to effectively separate pantoprazole and cinitapride with retention time of 7.17 min and 3.56 min, respe
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32

Rizal, Rosiana, Salman Salman, and Eka Wulandari. "FORMULASI CANGKANG KAPSUL DARI PEKTIN KULIT BUAH NANGKA (Artocarpus heterophyllus Lam) DAN UJI WAKTU HANCUR KAPSUL." Jurnal Ilmiah Farmasi Farmasyifa 6, no. 2 (2023): 187–202. http://dx.doi.org/10.29313/jiff.v6i2.11933.

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Capsule is capsule preparations which consisting of a drug in a soft capsule and hard capsule sell. Capsule is the preparations that most people used to discover the unpleasant taste of the drug. Most of capsule sell are made of gelatin, but it can also made with starch or other ingredients. The other ingredients which can substitute gelatin is pectin. Pectin is an ingredient belong to the class of carbohydrates. This study aim to find others alternative that can be used as new ingredients of capsule sell, which is jack fruit peels. Dissolved 20 mg jack fruit peels in 1000 ml of distilled wate
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PAL, AARATRIK, and MONORANJAN CHOWDHURY. "Torenia hookeri, a new combination in Asian Linderniaceae and first record of T. godefroyi in the Himalayan hotspot." Phytotaxa 549, no. 2 (2022): 230–34. http://dx.doi.org/10.11646/phytotaxa.549.2.8.

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Recent phylogenetic revision distinguishes Torenia from Vandellia by hairy or glabrous ovary and poricidal or septicidal capsule not extending the length of calyx (vs glabrous ovary and septicidal capsule clearly exceeding the calyx). Our current study showed that Vandellia hookeri exhibits all the characteristics of Torenia, therefore we change the generic treatment of V. hookeri to Torenia. Torenia godefroyi is also recorded from Himalayan Hotspot for the first time.
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34

Sugita, Purwantiningsih, Bambang Srijanto, Budi Arifin, and Ellin Vina Setyowati. "STABILITY OF KETOPROFEN COATED BY CHITOSAN-GUAR GUM GEL." Indonesian Journal of Chemistry 9, no. 3 (2010): 391–97. http://dx.doi.org/10.22146/ijc.21504.

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The coating stability of ketoprofen by chitosan-guar gum gel has been studied. Into 228.6 mL of 1.75% (w/v) chitosan solution in 1% (v/v) acetic acid, 38.1 mL of guar gum (gg) solution was added with concentration variation of 0.35, 0.55, and 0.75% (w/v) for ketoprofen microcapsules, and stirred with magnetic stirrer until homogenous. Afterwards, 7.62 mL of glutaraldehyde (glu) was added slowly under stirring, with concentrations varied: 3, 3.5, and 4% (v/v). All mixtures were shaked for 20 min for homogenization. Into each microcapsule mixture for ketoprofen, a solution of 2 g of ketoprofen i
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35

Srinivasu, K., J. Venkateswara Rao, N. Appala Raju, and K. Mukkanti. "A Validated RP-HPLC Method for the Determination of Atazanavir in Pharmaceutical Dosage Form." E-Journal of Chemistry 8, no. 1 (2011): 453–56. http://dx.doi.org/10.1155/2011/812879.

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A validated RP HPLC method for the estimation of atazanavir in capsule dosage form on YMC ODS 150 × 4.6 mm, 5 μ column using mobile phase composition of ammonium dihydrogen phosphate buffer (pH 2.5) with acetonitrile (55:45 v/v). Flow rate was maintained at 1.5 mL/min with 288 nm UV detection. The retention time obtained for atazanavir was at 4.7 min. The detector response was linear in the concentration range of 30 - 600 μg/mL. This method has been validated and shown to be specific, sensitive, precise, linear, accurate, rugged, robust and fast. Hence, this method can be applied for routine q
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36

Poole, C. A., S. Ayad, and R. T. Gilbert. "Chondrons from articular cartilage. V. Immunohistochemical evaluation of type VI collagen organisation in isolated chondrons by light, confocal and electron microscopy." Journal of Cell Science 103, no. 4 (1992): 1101–10. http://dx.doi.org/10.1242/jcs.103.4.1101.

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The pericellular microenvironment around articular cartilage chondrocytes must play a key role in regulating the interaction between the cell and its extracellular matrix. The potential contribution of type VI collagen to this interaction was investigated in this study using isolated canine tibial chondrons embedded in agarose monolayers. The immunohistochemical distribution of an anti-type VI collagen antibody was assessed in these preparations using fluorescence, peroxidase and gold particle probes in combination with light, confocal and transmission electron microscopy. Light and confocal m
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37

Polnaya, Febby Jeanry, Milian Tengker, and Vita Novalina Lawalata. "Pemanfaatan Pati Sagu pada Pembuatan Kapsul dengan Penambahan Gliserol." Jurnal Teknologi Hasil Pertanian 16, no. 1 (2023): 65. http://dx.doi.org/10.20961/jthp.v16i1.59502.

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<p><em>The purpose of this study was to determine the effect of several concentrations of glycerol in the manufacture of capsules from sago starch phosphate. Edible film testing includes physical, mechanical, and barrier film properties, while capsule testing includes moisture content, disintegration time, and dissolution. The design used was a completely randomized design consisting of a non-factorial with three levels of glycerol concentration (15, 25, and 35%, v/v). Variables measured were thickness, transparency, tensile strength and elongation, water vapor transmission rate, m
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38

Doshi, Ashish S., Sushil S. Bhagwan, Tushar N. Mehta, Vinod K. Gupta, and Gunta Subaaiah. "Determination of Nebivolol and Valsartan in a Fixed-Dose Combination by Liquid Chromatography." Journal of AOAC INTERNATIONAL 91, no. 2 (2008): 292–98. http://dx.doi.org/10.1093/jaoac/91.2.292.

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Abstract An accurate and reproducible liquid chromatographic assay method was developed and validated for the determination of nebivolol and valsartan in a capsule formulation. Bufferacetonitrile (55 + 45, v/v) was used for reversed-phase liquid chromatography to determine the contents of nebivolol and valsartan in the combination-capsule dosage form. The method was validated by determining parameters such as specificity, linearity, limits of detection and quantitation, precision, accuracy, and robustness. The method was found to be specific against placebo interference. Linearity was evaluate
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39

Negrini, D., M. I. Townsley, and A. E. Taylor. "Hydraulic conductivity of canine parietal pleura in vivo." Journal of Applied Physiology 69, no. 2 (1990): 438–42. http://dx.doi.org/10.1152/jappl.1990.69.2.438.

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The hydraulic conductivity (Lp) of the parietal pleura was measured in vivo in spontaneously breathing anesthetized dogs in either the supine (n = 8) or the prone (n = 7) position and in an excised portion of the chest wall in which the pleura and its adjacent tissue were intact (n = 3). A capsule was glued to the exposed parietal pleura after the intercostal muscles were removed. The capsule was filled with either autologous plasma or isotonic saline. Transpleural fluid flow (V) was measured at several transpleural hydrostatic pressures (delta P) from the rate of meniscus movement within a gr
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40

Gozet, Tuba, and Athar Alkhidhri. "UHPLC-DAD method development and validation for simultaneous quantification of 7 phenolic compounds in dietary supplements of sage capsulesa." Journal of Research in Pharmacy 29, no. 4 (2025): 1732–45. https://doi.org/10.12991/jrespharm.1734720.

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The content of the dietary supplements of capsules generated from extracts of medicinal plants in terms of bioactive compounds may not be known. The aim of this study is to do method development and validation for quantification of the phenolic compounds (chlorogenic acid, caffeic acid, syringic acid, p-coumaric acid, ferulic acid luteolin-7-o-glucoside, and rosmarinic acid) in capsules of dietary sage (Salvia officinalis) supplements by ultra-high performance liquid chromatography with diode array detector (UHPLC-DAD) to facilitate the quality control. Mobile phase gradient method is optimize
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41

Kulkarni, P. D., P. B. Wadikar, V. M. Nakhate, and A. Y. Patel. "The Evaluation of General and Specific Combining Ability Analysis in Sesame (Sesamum indicum L.)." Journal of Experimental Agriculture International 47, no. 7 (2025): 60–68. https://doi.org/10.9734/jeai/2025/v47i73546.

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The selection of appropriate parental lines for hybridization plays a crucial role in crop improvement programs, as the performance of the resulting hybrids can provide insights into their relative superiority. Hence, in any breeding program, the appropriate selection of parents based on their combining ability is essential. An attempt was made to study the general and specific combining ability in sesame (Sesamum indicum L.) through line x tester mating design. The four lines and seven testers were mated in line x tester fashion in Kharif 2024 and an evaluation study was conducted during Rabi
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42

B.Chitra, *. and T. K. Ravi. "DEVELOPMENT OF VALIDATED RP - HPLC METHOD FOR THE DETERMINATION OF ZIPRASIDONE HYDROCHLORIDE IN CAPSULE DOSAGE FORM." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 07 (2018): 6778–83. https://doi.org/10.5281/zenodo.1321261.

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This study presents a simple and rapid RP – HPLC method for the determination of ziprasidone hydrochloride in capsule dosage form. To optimize the chromatographic condition, the mobile phase system employed was potassium dihydrogen orthophosphate: ACN: methanol in the ratio of 30:70% v/v. The pH was adjusted to 4.9.The flow rate was maintained at 1ml /min.The developed method was validated for linearity, accuracy, precision, LOD and LOQ and recovery as per the ICH guidelines.Good linearity was obtained over the concentration ranges of 1-10 μg/ml. The percentage recovery was more than
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Wang, Yan-Hong, Cristina Avonto, Bharathi Avula, Mei Wang, Diego Rua та Ikhlas A. Khan. "Quantitative Determination of α-Arbutin, β-Arbutin, Kojic Acid, Nicotinamide, Hydroquinone, Resorcinol, 4-Methoxyphenol, 4-Ethoxyphenol, and Ascorbic Acid from Skin Whitening Products by HPLC-UV". Journal of AOAC INTERNATIONAL 98, № 1 (2015): 5–12. http://dx.doi.org/10.5740/jaoacint.14-123.

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Abstract An HPLC-UV method was developed for the quantitative analysis of nine skin whitening agents in a single injection. These compounds are α-arbutin, β-arbutin, kojic acid, nicotinamide, resorcinol, ascorbic acid, hydroquinone, 4-methoxyphenol, and 4-ethoxyphenol. The separation was achieved on a reversed-phase C18 column within 30 min. The mobile phase was composed of water and methanol, both containing 0.1% acetic acid (v/v). The stability of the analytes was evaluated at different pH values between 2.3 and 7.6, and the extraction procedurewas validated for different types of skin white
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44

Geng, Fang, Fashan Wang, Taobo Zou, et al. "Rapid Identification of the Multiple Absorbed Bioactive Components and Metabolites in Rat Serum after Oral Administration of Wu-Jia Sheng-Hua Capsule by UPLC-ESI-MS." Journal of Analytical Methods in Chemistry 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/318961.

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To identify the compounds absorbed in rat serum after the oral administration of Wu-Jia Sheng-Hua (WJSH) capsule, a traditional Chinese medicine (TCM) compound prescription, an ultraperformance liquid chromatography coupled with electrospray ionization mass spectrometry (UPLC/ESI-MS) method, was established. The chromatographic separation of the absorbed compounds and metabolites was achieved with an ACQUITY UPLC BEH C18 column (2.1 mm×50 mm, 1.7 μm) under a gradient elution. The mobile phase was composed of acetonitrile and water buffered with ammonium acetate (10 mM) and formic acid (0.1%, V
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45

Patel, Bhavesh H., Bhanubhai N. Suhagia, Madhabhai M. Patel, and Jignesh R. Patel. "Simultaneous Estimation of Pantoprazole and Domperidone in Pure Powder and a Pharmaceutical Formulation by High-Perfomance Liquid Chromatography and High-Performance Thin-Layer Chromatography Methods." Journal of AOAC INTERNATIONAL 90, no. 1 (2007): 142–46. http://dx.doi.org/10.1093/jaoac/90.1.142.

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Abstract This paper describes validated high-performance liquid chromatography (HPLC) and high-performance thin-layer chromatography (HPTLC) methods for the simultaneous estimation of pantoprazole (PANT) and domperidone (DOM) in pure powder and capsule formulations. The HPLC separation was achieved on a Phenomenex C18 column (250 mm id, 4.6 mm, 5 μm) using 0.01 M, 6.5 pH ammonium acetate buffer-methanol-acetonitrile (30 + 40 + 30, v/v/v, pH 7.20) as the mobile phase at a flow rate of 1.0 mL/min at ambient temperature. The HPTLC separation was achieved on an aluminum-backed layer of silica gel
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46

Berthold, Daniel P., Lukas N. Muench, Felix Dyrna, et al. "Comparison of Different Fixation Techniques of the Long Head of the Biceps Tendon in Superior Capsule Reconstruction for Irreparable Posterosuperior Rotator Cuff Tears: A Dynamic Biomechanical Evaluation." American Journal of Sports Medicine 49, no. 2 (2021): 305–13. http://dx.doi.org/10.1177/0363546520981559.

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Background: In the past decade, superior capsular reconstruction has emerged as a potential surgical approach in young patients with irreparable posterosuperior rotator cuff tears (RCT) and absence of severe degenerative changes. Recently, the use of locally available and biological viable autografts, such as the long head of the biceps tendon (LHBT) for SCR has emerged, with promising early results. Purpose/Hypothesis: The purpose of this study was to investigate the effect of using the LHBT for reconstruction of the superior capsule on shoulder kinematics, along with different fixation const
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47

Haq, Nazrul, Faiyaz Shakeel, Mohammed M. Ghoneim, et al. "Determination of Pterostilbene in Pharmaceutical Products Using a New HPLC Method and Its Application to Solubility and Stability Samples." Separations 10, no. 3 (2023): 178. http://dx.doi.org/10.3390/separations10030178.

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The quantification of a natural bioactive compound, pterostilbene (PTT), in commercial capsule dosage form, solubility, and stability samples was carried out using a rapid and sensitive high-performance liquid chromatography (HPLC) approach. PTT was quantified on a Nucleodur (150 mm × 4.6 mm) RP C18 column with a particle size of 5 µm. Acetonitrile and water (90:10 v/v) made up the mobile phase, which was pumped at a flow speed of 1.0 mL/min. At a wavelength of 254 nm, PTT was detected. The developed HPLC approach was linear in 1–75 µg/g range, with a determination coefficient of 0.9995. The d
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48

Lamari, Faouzi, Sadok Khouadja, and Sami Rtimi. "Interaction of Vibrio to Biotic and Abiotic Surfaces: Relationship between Hydrophobicity, Cell Adherence, Biofilm Production, and Cytotoxic Activity." Surfaces 1, no. 1 (2018): 187–201. http://dx.doi.org/10.3390/surfaces1010014.

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Vibrio parahaemolyticus and Vibrio alginolyticus are important pathogenic agents for both humans and aquatic animals. Twenty-five bacterial strains were isolated from infected sea bass (Dicentrarchus labrax) on thiosulfate citrate bile salts sucrose (TCBS) agar plates. For the species-specific detection of V. alginolyticus and V. parahaemolyticus, a multiplex PCR assay using two collagenase-targeted primer pairs allows the detection of four strains of V. parahaemolyticus and three strains of V. alginolyticus. The seven identified isolates were partitioned for capsule production, hydrophobicity
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49

Blakiewicz, G., J. Jakusz, W. Jendernalik, and S. Szczepański. "Automatic tuning of a resonant circuit in wireless power supply systems for biomedical sensors." Bulletin of the Polish Academy of Sciences Technical Sciences 64, no. 3 (2016): 641–46. http://dx.doi.org/10.1515/bpasts-2016-0072.

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Abstract In this paper, a tuning method of a resonant circuit suited for wireless powering of miniature endoscopic capsules is presented and discussed. The method allows for an automatic tuning of the resonant frequency and matching impedance of a full wave rectifier loading the resonant circuit. Thereby, the receiver tunes so as to obtain the highest power efficiency under given conditions of transmission. A prototype receiver for wireless power reception, fabricated in in AMS CMOS 0.35 μm technology, was used to verify correct operation of the proposed tuning. The prototype system produces a
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50

Jiang, Zhenyu, Boning Deng, Yaqi Zhang, et al. "Efficacy and safety of seven Chinese patent medicines combined with conventional triple/quadruple therapy forHelicobacter pylori-positive peptic ulcers: a systematic review and network meta-analysis." BMJ Open 14, no. 4 (2024): e074188. http://dx.doi.org/10.1136/bmjopen-2023-074188.

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ObjectivesTo compare the efficacy and safety of seven Chinese patent medicines (CPMs) combined with conventional triple/quadruple therapy (T/Q) forHelicobacter pylori-positive peptic ulcers.DesignA systematic review and network meta-analysis.Data sourcesChina National Knowledge Infrastructure, VIP database, Wanfang database, ScienceDirect, EBSCO, EMBASE, Web of Science, Cochrane Library and PubMed were searched through 1 June 2022.Eligibility criteriaRandomised controlled trials (RCTs) testing CPMs combined with T/Q forH. pylori-positive peptic ulcers were included. The CPMs included Anweiyang
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