Academic literature on the topic 'Carbazole Alkaloids'

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Journal articles on the topic "Carbazole Alkaloids"

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Chakraborty, M. "Mumunine - A New Carbazole Alkaloid from Murraya koenigii (Linn.) Spreng." Journal of Scientific Research 12, no. 4 (2020): 665–72. http://dx.doi.org/10.3329/jsr.v12i4.45499.

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The plant Murraya koenigii, commonly known as curry leaf tree is a rich source of carbazole alkaloids. A number of monomeric as well as dimeric carbazoles with C13, C18 and C23 skeleton have been isolated from the plant. In my present work, a new carbazole alkaloid, designated as mumunine, was isolated from the bark of Murraya koenigii (Linn) Spreng, along with a known carbazole alkaloid, viz. mahanimbine. The structure of the new alkaloid 1 was elucidated on the basis of 1D and 2D NMR spectral data analysis. In this paper, the isolation and structure elucidation of the new compound will be di
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Kumar, V., J. Reisch, and A. Wickramasinghe. "Glycomaurin and Glycomaurrol, New Carbazole Alkaloids From Glycosmis mauritiana (Rutaceae) Bark." Australian Journal of Chemistry 42, no. 8 (1989): 1375. http://dx.doi.org/10.1071/ch9891375.

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The stem bark of Glycosmis mauritiana contained the acridone alkaloids noracronycine and des-N- methylacronycine, and two new carbazole alkaloids, 3,3,10-trimethyl-3,7-dihydropyrano[2,3-c] carbazole (glycomaurin) and 6-methyl-4-(3′-methylbut-2′-enyl)carbazol-3-ol (glycomaurrol), whose structures were confirmed by synthesis and by cyclization to dihydroglycomaurin respectively. Glycomaurin has a ring system which has not been previously found in nature.
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Yang, Jing-Hua, Xin-Yi Wang, Yi-Ping Zhou, et al. "Carbazole Alkaloids from Clausena anisum-olens: Isolation, Characterization, and Anti-HIV Evaluation." Molecules 25, no. 1 (2019): 99. http://dx.doi.org/10.3390/molecules25010099.

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Two new carbazole alkaloids (1,2) and six known carbazole alkaloids (3–8) were isolated from Clausena anisum-olens. Their structures were elucidated based on extensive spectroscopic analysis. All isolated compounds (1–8) were evaluated for their anti-HIV effects on virus replication in MT-4 lymphocytes infected by HIV-1NL4-3 Nanoluc-sec virus, and new carbazole alkaloid 1 exhibited anti-HIV activity with an EC50 value of 2.4 μg/mL and SI of 7.1.
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Kobayashi, Masaya, and Tomohisa Kuzuyama. "Recent Advances in the Biosynthesis of Carbazoles Produced by Actinomycetes." Biomolecules 10, no. 8 (2020): 1147. http://dx.doi.org/10.3390/biom10081147.

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Structurally diverse carbazole alkaloids are valuable due to their pharmaceutical properties and have been isolated from nature. Experimental knowledge on carbazole biosynthesis is limited. The latest development of in silico analysis of the biosynthetic gene clusters for bacterial carbazoles has allowed studies on the biosynthesis of a carbazole skeleton, which was established by sequential enzyme-coupling reactions associated with an unprecedented carbazole synthase, a thiamine-dependent enzyme, and a ketosynthase-like enzyme. This review describes the carbazole biosynthetic mechanism, which
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Ma, Xiaoli, Hongwei Chen, Sisi Zhu, Pengfei Tu, and Yong Jiang. "Trimeric and Dimeric Carbazole Alkaloids from Murraya microphylla." Molecules 26, no. 18 (2021): 5689. http://dx.doi.org/10.3390/molecules26185689.

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Seventeen new carbazole alkaloid derivatives, including a trimeric carbazole racemate, (±)-microphyltrine A (1), 15 dimeric carbazole racemates, (±)-microphyldines A–O (2–16), and a C-6–C-3″-methyl-linked dimeric carbazole, microphyldine P (17), were isolated from the leaves and stems of Murraya microphylla (Merr. et Chun) Swingle. The structures of the new compounds were elucidated on the basis of HRESIMS and NMR data analysis. The optically pure isomers of these isolated carbazole alkaloids were obtained by chiral HPLC separation and their absolute configurations were determined by electroni
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Mandal, Suvra, Anupam Nayak, Samir K. Banerjee, Julie Banerji, and Avijit Banerji. "A New Carbazole Alkaloid from Murraya koenigii Spreng (Rutaceae)." Natural Product Communications 3, no. 10 (2008): 1934578X0800301. http://dx.doi.org/10.1177/1934578x0800301019.

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A new carbazole alkaloid (kurryam) oxygenated at the 4-position, hitherto unknown among carbazole alkaloids, has been isolated from the seeds of an Indian medicinal plant, Murraya koenigii (Rutaceae). The structure has been established as 4-hydroxy-(2′,2′,3)-trimethyl-(6,7)-dimethoxy pyranocarbazole from extensive 2D NMR spectral studies. In addition, two known carbazole alkaloids, (2′,2′,3)-trimethyl 6-methoxy pyranocarbazole and (2′,2′,3)-trimethyl 6-hydroxy pyranocarbazole were isolated from the seeds of the same plant, of which (2′,2′,3)-trimethyl 6-methoxy pyranocarbazole exhibited signif
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Chakraborty, Mumu, Sudipta Saha, and Sibabrata Mukhapadhyay. "Murrayakoeninol- A New Carbazole Alkaloid from Murraya Koenigii (Linn) Spreng." Natural Product Communications 4, no. 3 (2009): 1934578X0900400. http://dx.doi.org/10.1177/1934578x0900400309.

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A new carbazole alkaloid, designated as murrayakoeninol, was isolated from the leaves of Murraya koenigii (Linn) Spreng, along with four known carbazole alkaloids, viz. mahanimbine, koenimbine, O-methylmurrayamine-A and murrayazolinine and one from the bark viz. girinimbine. The structure of the new alkaloid 1 was elucidated on the basis of 2D NMR spectral analysis and chemical reactions.
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Chakraborty, M. "Identification of Naturally Occurring Carbazole Alkaloids Isolated from <i>Murraya koenigii</i> and <i>Glycosmis pentaphylla</i> by the Preparation of HPLC Fingerprint." Journal of Scientific Research 14, no. 1 (2022): 289–300. http://dx.doi.org/10.3329/jsr.v14i1.53526.

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The plants Murraya koenigii and Glycosmis pentaphylla are rich sources of different carbazole alkaloids. A number of monomeric carbazole alkaloids with C13, C18, and C23 carbon frames and a good number of dimeric carbazole alkaloids were isolated from these two plants. Scientists are still working on these two plants in search of more and more novel compounds. Many of these alkaloids have potential biological activities. Scientists have determined the structures of these compounds by detailed analysis of spectral data like UV, IR, Mass,1H NMR, and 13C NMR (1D and 2D). These procedures require
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Moody, Christopher J. "Synthesis of Carbazole Alkaloids." Synlett 1994, no. 09 (1994): 681–88. http://dx.doi.org/10.1055/s-1994-22975.

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Bergman, J., and B. Pelcman. "Synthesis of carbazole alkaloids." Pure and Applied Chemistry 62, no. 10 (1990): 1967–76. http://dx.doi.org/10.1351/pac199062101967.

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Dissertations / Theses on the topic "Carbazole Alkaloids"

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Hesse, Ronny, Anne Jäger, Arndt W. Schmidt, and Hans-Joachim Knölker. "Palladium(II)-catalysed total synthesis of naturally occurring pyrano[3,2-a]carbazole and pyrano[2,3-b]carbazole alkaloids." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-149135.

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Seven naturally occurring pyranocarbazole alkaloids (pyrayafoline A–E, O-methylmurrayamine A and O-methylmahanine) have been obtained by total synthesis using a palladium(II)-catalysed oxidative cyclisation of a diarylamine to an orthogonally diprotected 2,7-dihydroxycarbazole as key step.
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Markad, S. B. "Studies on total synthesis of bioactive carbazole alkaloids." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2017. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/4267.

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Scott, Tricia L. "Palladium-catalyzed synthesis of carbazole derivatives and formal total syntheses of several naturally occurring carbazole alkaloids." Morgantown, W. Va. : [West Virginia University Libraries], 2001. http://etd.wvu.edu/templates/showETD.cfm?recnum=2075.

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Thesis (Ph. D.)--West Virginia University, 2001.<br>Title from document title page. Document formatted into pages; contains x, 83 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 75-78).
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Knott, Kerstin. "Iron-mediated Synthesis of the Antiostatins." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2009. http://nbn-resolving.de/urn:nbn:de:bsz:14-ds-1237582907592-42405.

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Within this thesis the first total syntheses of eight biologically active natural products from the family of carbazole alkaloids, antiostatins A1 to A4 and B2 to B5, were established. Spectroscopic data of the synthesised natural products are in good agreement with the isolated antiostatins from Streptomyces cyaneus 2007-SV1, which confirms the molecular structures assigned to the natural products. The total synthesis of the antiostatins A1 to A4 and B2 to B5 were achieved employing the iron-mediated synthesis to form the carbazole nucleus from a cyclohexadienylium iron salt and appropriate a
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Gassner, Cemena, Ronny Hesse, Arndt W. Schmidt, and Hans-Joachim Knölker. "Total synthesis of the cyclic monoterpenoid pyrano[3,2-a]carbazole alkaloids derived from 2-hydroxy-6-methylcarbazole." Royal Society of Chemistry, 2014. https://tud.qucosa.de/id/qucosa%3A28532.

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Knott, Kerstin. "Iron-mediated Synthesis of the Antiostatins." Doctoral thesis, Technische Universität Dresden, 2008. https://tud.qucosa.de/id/qucosa%3A24053.

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Within this thesis the first total syntheses of eight biologically active natural products from the family of carbazole alkaloids, antiostatins A1 to A4 and B2 to B5, were established. Spectroscopic data of the synthesised natural products are in good agreement with the isolated antiostatins from Streptomyces cyaneus 2007-SV1, which confirms the molecular structures assigned to the natural products. The total synthesis of the antiostatins A1 to A4 and B2 to B5 were achieved employing the iron-mediated synthesis to form the carbazole nucleus from a cyclohexadienylium iron salt and appropriate a
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Gassner, Cemena, Ronny Hesse, Arndt W. Schmidt, and Hans-Joachim Knölker. "Total synthesis of the cyclic monoterpenoid pyrano[3,2-a]carbazole alkaloids derived from 2-hydroxy-6-methylcarbazole." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-160632.

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Shi, Chongsheng. "Synthesis of benzocarbazoles, indoloquinolines and indolonaphthridines from thermolysis of benzoenynyl ketenimines and carbodiimides." Morgantown, W. Va. : [West Virginia University Libraries], 2001. http://etd.wvu.edu/templates/showETD.cfm?recnum=2119.

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Thesis (Ph. D.)--West Virginia University, 2001.<br>Title from document title page. Document formatted into pages; contains ix, 82 p. : ill. Includes abstract. Includes bibliographical references (p. 70-80).
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Krahl, Micha P. "Regioselektive Synthese oxygenierter Carbazole." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2007. http://nbn-resolving.de/urn:nbn:de:swb:14-1168004377329-87485.

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In der heutigen Wirkstoffforschung stellen vor allem multiresistente Krankheitserreger eine große Herausforderung an die Wissenschaft dar. Noch sterben z.B. an der Tuberkulose jährlich etwa 1.7 Millionen Menschen, davon 69000 allein in Europa (WHO-Angaben, 2004). Die Tuberkulose verursacht neben AIDS die meisten Todesfälle unter den Infektionskrankheiten. Ein großes Problem sind die zahlreichen Neuerkrankungen, die mit herkömmlichen Mitteln nicht mehr behandelt werden können, sowie zunehmende Medikamentenallergien. Somit ist ein wichtiges Gebiet der Wirkstoff-forschung, neben der Weiterentwick
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Krahl, Micha P. "Regioselektive Synthese oxygenierter Carbazole." Doctoral thesis, Technische Universität Dresden, 2006. https://tud.qucosa.de/id/qucosa%3A24953.

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In der heutigen Wirkstoffforschung stellen vor allem multiresistente Krankheitserreger eine große Herausforderung an die Wissenschaft dar. Noch sterben z.B. an der Tuberkulose jährlich etwa 1.7 Millionen Menschen, davon 69000 allein in Europa (WHO-Angaben, 2004). Die Tuberkulose verursacht neben AIDS die meisten Todesfälle unter den Infektionskrankheiten. Ein großes Problem sind die zahlreichen Neuerkrankungen, die mit herkömmlichen Mitteln nicht mehr behandelt werden können, sowie zunehmende Medikamentenallergien. Somit ist ein wichtiges Gebiet der Wirkstoff-forschung, neben der Weiterentwick
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Books on the topic "Carbazole Alkaloids"

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Bauermeister, Michael. Eisen-vermittelter Aufbau von Carbazol-Alkaloiden. 1991.

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Book chapters on the topic "Carbazole Alkaloids"

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Bhattacharyya, P., and D. P. Chakraborty. "Carbazole Alkaloids." In Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products. Springer Vienna, 1987. http://dx.doi.org/10.1007/978-3-7091-8906-1_4.

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Chakraborty, D. P., and Shyamali Roy. "Carbazole Alkaloids III." In Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products. Springer Vienna, 1991. http://dx.doi.org/10.1007/978-3-7091-9119-4_2.

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Chakraborty, D. P., and Shyamali Roy. "Carbazole Alkaloids IV." In Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products. Springer Vienna, 2003. http://dx.doi.org/10.1007/978-3-7091-6051-0_3.

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Bergman, Jan, and Benjamin Pelcman. "Synthetic Approaches to Carbazole Alkaloids." In Natural Products Chemistry III. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-74017-6_11.

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Bauer, Ingmar, and Hans-Joachim Knölker. "Synthesis of Pyrrole and Carbazole Alkaloids." In Topics in Current Chemistry. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/128_2011_192.

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Knölker, Hans-Joachim. "Occurrence, Biological Activity, and Convergent Organometallic Synthesis of Carbazole Alkaloids." In Topics in Current Chemistry. Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/b96890.

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Matsuoka, Junpei. "Construction of the Pyrrolo[2,3-d]Carbazole Core of Spiroindoline Alkaloids by Gold-Catalyzed Cascade Cyclization of Ynamide." In Total Synthesis of Indole Alkaloids. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-8652-1_3.

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Roland Ebede, Guy, Lin Marcellin Messi, Jean Faustin Atangana, et al. "Recent Experimental Approaches Used for the Isolation and Characterization of Indole Alkaloids, Carbazoles, and Saponosides from Sub-Saharan Medicinal Plants." In Propagation to Pharmacopeia. CRC Press, 2024. http://dx.doi.org/10.1201/9781003423416-10.

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Knölker, Hans-Joachim, and Kethiri R. Reddy. "Biogenesis of Carbazole Alkaloids." In The Alkaloids: Chemistry and Biology. Elsevier, 2008. http://dx.doi.org/10.1016/s1099-4831(07)00003-x.

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Knölker, Hans-Joachim, and Kethiri R. Reddy. "Chemistry of Carbazole Alkaloids." In The Alkaloids: Chemistry and Biology. Elsevier, 2008. http://dx.doi.org/10.1016/s1099-4831(07)00005-3.

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Conference papers on the topic "Carbazole Alkaloids"

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Thant, Tin Myo, Nanik Siti Aminah, Alfinda Novi Kristanti, Rico Ramadhan, Hnin Thanda Aung, and Yoshiaki Takaya. "Cytotoxic Carbazole Alkaloid from the Root of Clausena cxcavata on Hela Cell Line." In International Conference on Chemical Science and Technology Innovation. SCITEPRESS - Science and Technology Publications, 2019. http://dx.doi.org/10.5220/0008858101410144.

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Boonsnongcheep, P., S. Daodee, T. Kitisripanya, and W. Putalun. "Enhanced carbazole alkaloid and antioxidant capacity in callus culture of medicinal plant Clausena harmandiana by Bacilius subtilis elicitor." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399792.

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Stadlbauer, Wolfgang, Daniel Rieder, Birgit Schuiki, and Thomas Kappe. "Syntheses, Substitution and Cyclization Reactions of 7a,8,9,10,11a-Hexahydro-pyrido[3,2,1-jk]carbazoles With a Strychnos Alkaloids Partial Structure." In The 20th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-a001.

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Stadlbauer, Wolfgang, Ali Deeb, Urška Erklavec, et al. "Syntheses and Reactions of 5-Unsubstituted 11b-Methyl-1,2,3,11b-tetrahydro-pyrido[3,2,1-jk]carbazoles Having a Strychnos Alkaloids Partial Structure." In The 19th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2015. http://dx.doi.org/10.3390/ecsoc-19-a041.

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Stadlbauer, Wolfgang, Ali Deeb, Urška Erklavec, Daniel Rieder, and Birgit Schuiki. "Syntheses and Reactions of 5-Alkyl- and 5-Aryl-11b-Methyl-1,2,3,11b-Tetrahydro-Pyrido[3,2,1-jk]carbazoles Having a Strychnos Alkaloids Partial Structure." In The 18th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2014. http://dx.doi.org/10.3390/ecsoc-18-a005.

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