Log in

Relevant bibliographies by topics / Carbazole derivatives / Journal articles

To see the other types of publications on this topic, follow the link: Carbazole derivatives.

Journal articles on the topic 'Carbazole derivatives'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Carbazole derivatives.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Manu, Tripathi* Shweta Shukla Meera Kumari Amresh Gupta. "Recent advancement of carbazole hybrid: a privileged scaffold in new drug discovery." International Journal of Advances in Pharmacy Medicine and Bioallied Sciences 10, no. 3 (2022): 123–34. https://doi.org/10.5281/zenodo.7709108.

Full text

Abstract:

Carbazole comprises an important class of heterocycles. Carbazole is a tricyclic molecule having a coal tar carbon backbone, and also it has the structural properties of numerous compounds used in electronics for the manufacturing of polymers or dyes and electroluminescent materials, owing to its luminous quality. It has been reported that diverse biological activities include anti-cytotoxicity, bacteria-related problems, neurological problems, etc. Some carbazole derivatives were created such carbazoles with N-substitution, benzocarbazoles, furocarbazoles, pyrrolo-carbazoles, imidazo-carbazol

APA, Harvard, Vancouver, ISO, and other styles

2

Sweta, Shukla, and Gupta Sujeet. "Carbazole derivatives: an attractive scaffold in anticancer lead discovery." International Journal of Advances in Pharmacy Medicine and Bioallied Sciences 10, no. 2 (2022): 88–93. https://doi.org/10.5281/zenodo.7066183.

Full text

Abstract:

Cancer is one of the leading chronic diseases with a high mortality rate worldwide.  Current statistical studies on cancer estimates from the World Health Organization (WHO) in 2020, cancer is the first or second leading cause of death. Although cancer remains a devastating diagnosis, several decades of preclinical progress in cancer biology and biotechnology have recently led to the successful development of several biological agents that substantially improve survival and quality of life for some patients. For over half a century, the carbazole skeleton has been the key structural motif

APA, Harvard, Vancouver, ISO, and other styles

3

Karaaslan, Cigdem, Hande Gurer-Orhan, Sibel Suzen, et al. "Behaviour of 9-Ethyl-9H-carbazole Hydrazone Derivatives Against Oxidant Systems." Croatica chemica acta 92, no. 1 (2019): 87–94. http://dx.doi.org/10.5562/cca3481.

Full text

Abstract:

Antioxidants are helpful in prevention of several diseases related with oxidative stress including neurodegenerative disorders. In recent studies, carbazoles were given proof of promising antioxidant activities. In this article, 9-ethyl-9H-carbazole hydrazone derivatives were synthesized, characterized and their in vitro antioxidant activity and possible cytotoxic effects were investigated. Furthermore, protective effect of the synthesized derivatives against amyloid β-induced damage in PC12 neuronal cells was examined by using MTT assay. The newly synthesized carbazoles were found to have rad

APA, Harvard, Vancouver, ISO, and other styles

4

Alrashdi, Saad, Federica Casolari, Kwaku Kyeremeh, and Hai Deng. "Chemo-Enzymatic Synthesis of Bioactive Carbazole Derivatives." SynBio 2, no. 1 (2024): 21–30. http://dx.doi.org/10.3390/synbio2010002.

Full text

Abstract:

Carbazoles are key scaffolds of either antimicrobial/antiviral alkaloid natural products or therapeutics. As such, access to structurally diverse indole-containing carbazoles has attracted considerable attention. In this report, a pilot study is described using biotransformation to provide carbazoles that contain various acyl substituents. The biotransformation system contains the thiamine-diphosphate (ThDP)-dependent enzyme NzsH, the FabH-like 3-ketoacyl-ACP synthase NzsJ, and the aromatase/cyclase NzsI, encoded in the biosynthetic gene cluster (nzs) of the bacterial carbazole alkaloid natura

APA, Harvard, Vancouver, ISO, and other styles

5

Irgashev, Roman A., Nikita A. Kazin, Gennady L. Rusinov, and Valery N. Charushin. "Nitration of 5,11-dihydroindolo[3,2-b]carbazoles and synthetic applications of their nitro-substituted derivatives." Beilstein Journal of Organic Chemistry 13 (July 14, 2017): 1396–406. http://dx.doi.org/10.3762/bjoc.13.136.

Full text

Abstract:

A new general approach to double nitration of 6,12-di(hetero)aryl-substituted and 6,12-unsubstituted 5,11-dialkyl-5,11-dihydroindolo[3,2-b]carbazoles by acetyl nitrate has been developed to obtain their 2,8-dinitro and 6,12-dinitro derivatives, respectively. A formation of mono-nitro derivatives (at C-2 or C-6) from the same indolo[3,2-b]carbazoles has also been observed in several cases. Reduction of 2-nitro and 2,8-dinitro derivatives with zinc powder and hydrochloric acid has afforded 2-amino- and 2,8-diamino-substituted indolo[3,2-b]carbazoles, while reduction of 6,12-dinitro derivatives u

APA, Harvard, Vancouver, ISO, and other styles

6

Nitin Kumar, Neetika lal, Vishal Nemaysh, and Pratibha Mehta Luthra. "Synthesis and in vitro anticancer activity of novel 1,4-dimethyl-9-H-carbazol-3-yl) methanamine derivatives against human glioma U87 MG cell line." World Journal of Advanced Research and Reviews 19, no. 1 (2023): 1099–108. http://dx.doi.org/10.30574/wjarr.2023.19.1.1446.

Full text

Abstract:

Glioblastoma Multiforme (GBM) is most aggressive type of brain tumor in adults. 1,4-dimethyl carbazoles exhibits significant anticancer activities in literature. In this research article, we synthesized a series of novel 1,4-dimethyl-9-H-carbazol-3-yl)methanamine and its derivatives (13-24) and evaluated their in vitro cytotoxicity activities against human glioma U87 MG cell line using MTT assay for 24 h phase time period. All final carbazole derivatives were well confirmed by NMR and HRMS spectroscopy techniques. In series, few compound (15-17) found excellent in vitro anticancer activity (IC

APA, Harvard, Vancouver, ISO, and other styles

7

Jurczak, Janusz, Agnieszka Cholewiak, and Pawel Stepniak. "Linear Neutral Receptors for Anions: Synthesis, Structure and Applications." Synthesis 50, no. 23 (2018): 4555–68. http://dx.doi.org/10.1055/s-0037-1609943.

Full text

Abstract:

A selective digest of linear anion receptors based on different aromatic skeletons is presented. Since the structures of anions vary from one to another, different strategies have been developed over recent years in order to bind anions efficiently and selectively. Rigidity, number of hydrogen bond donors, steric hindrance, and special preorganization of linear receptors are analyzed to shed light on the rational design of anion receptors.1 Introduction2 1,3- and 1,2-Benzene Derivatives3 1,3- and 5,7-Azulene Derivatives4 1,8-Naphthalene Derivatives5 1,8-Anthracene Derivatives6 2,6-Pyridine Der

APA, Harvard, Vancouver, ISO, and other styles

8

Caruso, Anna, Alexia Barbarossa, Alessia Carocci, Giovanni Salzano, Maria Stefania Sinicropi, and Carmela Saturnino. "Carbazole Derivatives as STAT Inhibitors: An Overview." Applied Sciences 11, no. 13 (2021): 6192. http://dx.doi.org/10.3390/app11136192.

Full text

Abstract:

The carbazole class is made up of heterocyclically structured compounds first isolated from coal tar. Their structural motif is preponderant in different synthetic materials and naturally occurring alkaloids extracted from the taxonomically related higher plants of the genus Murraya, Glycosmis, and Clausena from the Rutaceae family. Concerning the biological activity of these compounds, many research groups have assessed their antiproliferative action of carbazoles on different types of tumoral cells, such as breast, cervical, ovarian, hepatic, oral cavity, and small-cell lung cancer, and unde

APA, Harvard, Vancouver, ISO, and other styles

9

Çiçek, Baki, Merve Çağlı, Remziye Tülek, and Ali Teke. "Synthesis and optical characterization of bipod carbazole derivatives." Heterocyclic Communications 26, no. 1 (2020): 148–56. http://dx.doi.org/10.1515/hc-2020-0111.

Full text

Abstract:

AbstractIn this study, some new biscarbazole derivatives were synthesized for the purpose of being used in OLED technologies and related areas. The following compounds: {1,2-bis(2-(3,6-diphenyl-9H-carbazole-9-yl) ethoxy)ethane (C-1), bis[2-(2-(3,6- diphenyl-9H-carbazole-9-yl) ethoxy)etyl]ether (C-2), bis[2-(2-(3,6-di(naphthalene-1-yl)-9H-carbazol-9-yl)ethoxy)etyl]ether (C-3) and bis [2-(2-(3,6-di(naphthalene-2-yl)-9H-carbazol-9-yl)ethoxy) ethyl]ether (C-4) were synthesized by Suzuki-Miyaura Cross Coupling reactions. The structural properties of the synthesized compounds were characterized by F

APA, Harvard, Vancouver, ISO, and other styles

10

Wantulok, Jakub, Daniel Swoboda, Jacek E. Nycz, et al. "Direct Amination of Nitroquinoline Derivatives via Nucleophilic Displacement of Aromatic Hydrogen." Molecules 26, no. 7 (2021): 1857. http://dx.doi.org/10.3390/molecules26071857.

Full text

Abstract:

The vicarious nucleophilic substitution of hydrogen (VNS) reaction in electron-deficient nitroquinolines was studied. Properties of all new products have been characterized by several techniques: MS, HRMS, FTIR, GC-MS, electronic absorption spectroscopy, and multinuclear NMR. The structures of 4-chloro-8-nitroquinoline, 8-(tert-butyl)-2-methyl-5-nitroquinoline, 9-(8-nitroquinolin-7-yl)-9H-carbazole and (Z)-7-(9H-carbazol-9-yl)-8-(hydroxyimino)quinolin-5(8H)-one were determined by single-crystal X-ray diffraction measurements. The 9-(8-nitroquinolin-7-yl)-9H-carbazole and (Z)-7-(9H-carbazol-9-y

APA, Harvard, Vancouver, ISO, and other styles

11

Nitin, Kumar, lal Neetika, Nemaysh Vishal, and Mehta Luthra Pratibha. "Synthesis and in vitro anticancer activity of novel 1,4-dimethyl-9-H-carbazol-3-yl) methanamine derivatives against human glioma U87 MG cell line." World Journal of Advanced Research and Reviews 19, no. 1 (2023): 1099–108. https://doi.org/10.5281/zenodo.10295738.

Full text

Abstract:

Glioblastoma Multiforme (GBM) is most aggressive type of brain tumor in adults. 1,4-dimethyl carbazoles exhibits significant anticancer activities in literature. In this research article, we synthesized a series of novel 1,4-dimethyl-9-<i>H</i>-carbazol-3-yl)methanamine  and its derivatives (13-24) and evaluated their <i>in vitro</i> cytotoxicity activities against human glioma U87 MG cell line using MTT assay for 24 h phase time period. All final carbazole derivatives were well confirmed by NMR and HRMS spectroscopy techniques. In series, few compound (<strong>15-17</strong>) found excel

APA, Harvard, Vancouver, ISO, and other styles

12

Murali, Karunanidhi, Hazel A. Sparkes, Baskaran Vijaya Pandiyan, and Karnam Jayarampillai Rajendra Prasad. "Synthesis, photophysical properties and DFT analysis of highly substituted pyrido carbazole-based “push pull” chromophores." New Journal of Chemistry 41, no. 16 (2017): 8242–52. http://dx.doi.org/10.1039/c7nj00643h.

Full text

Abstract:

A series of new fluorescent pyrido[2,3-a]carbazole derivatives were synthesized based on a four component reaction with 2,3,4,9-tetrahydro-1H-carbazol-1-one, malononitrile, and aryl/heteroaryl aldehydes in presence of NaOEt.

APA, Harvard, Vancouver, ISO, and other styles

13

Yan, Hua, Tomoko Chiba Mizutani, Nobuhiko Nomura, et al. "A Novel Small Molecular Weight Compound with a Carbazole Structure That Demonstrates Potent Human Immunodeficiency Virus Type-1 Integrase Inhibitory Activity." Antiviral Chemistry and Chemotherapy 16, no. 6 (2005): 363–73. http://dx.doi.org/10.1177/095632020501600603.

Full text

Abstract:

The integration of reverse transcribed proviral DNA into a host genome is an essential event in the human immunodeficiency virus type 1 (HIV-1) replication life cycle. Therefore, the viral enzyme integrase (IN), which plays a crucial role in the integration event, has been an attractive target of anti-retroviral drugs. Several IN inhibitory compounds have been reported previously, yet none has been successful in clinical use. To find a new, more successful IN inhibitor, we screened a diverse library of 12000 small molecular weight compounds randomly by in vitro strand-transfer assay. We identi

APA, Harvard, Vancouver, ISO, and other styles

14

Caruso, Anna, Jessica Ceramella, Domenico Iacopetta, et al. "Carbazole Derivatives as Antiviral Agents: An Overview." Molecules 24, no. 10 (2019): 1912. http://dx.doi.org/10.3390/molecules24101912.

Full text

Abstract:

Viruses represent the most common cause of infectious diseases worldwide and those with rapid propagation and high infection rates cause human and animal pandemics. These fast-spreading diseases are generally treated with antiviral drugs but, often, drug resistance occurs because of the ability of the pathogens to mutate rapidly and become less susceptible to the treatments. Even though new antivirals have been approved, e.g., in HIV (human immunodeficiency virus) and HCV (hepatitis C virus) therapeutic areas, the need to dispose of new pharmaceutical tools for the management of infections tha

APA, Harvard, Vancouver, ISO, and other styles

15

(Miss), B. CHOUDHURY, KUMAR P., ROY CHOUDHURY B., and P. DAS B. "Larvicidal Activity of some Carbazoles." Journal of Indian Chemical Society Vol. 68, Jan 1991 (1991): 64–65. https://doi.org/10.5281/zenodo.6101130.

Full text

Abstract:

Durgapur Women's College. Durgapur and Department of Chemistry. Visva-Bharati, Santiniketan-731 235 <em>Manuscript received 29 May 1990. revised 8 October 1990, accepted 28 November 1990</em> In consideration of the biological properties of carbazoles<sup>1</sup> and our interest in the pesticidal and larvicidal activities<sup>2-4</sup> of carbazoles, we report here the preparation of some new carbazole derivatives with a view to examine their larvicidal activities. We also report the biological activities of these compounds as well as some carbazoles of known structures.

APA, Harvard, Vancouver, ISO, and other styles

16

Sharma, Divyanshu, Nitin Kumar, and Devender Pathak. "Synthesis, characterization and biological evaluation of some newer carbazole derivatives." Journal of the Serbian Chemical Society 79, no. 2 (2014): 125–32. http://dx.doi.org/10.2298/jsc130123069s.

Full text

Abstract:

A series of novel 5-((9H-carbazol-9-yl)methyl)-N-((substituted phenyl)(piperazin-1-yl)methyl)-1,3,4-oxadiazol-2-amine (4a-4o) derivatives was synthesized by starting with carbazole which on reaction with ethyl choloroacetate yielded ethyl 2-(9H-carbazole-9-yl)acetate (1), compound (1) on reaction with semicarbazide followed by cyclisation with sulphuric acid gave 5-((9H-carbazole-9-yl)-1,3,4-oxadiazol-2-amine (3) which through Mannich reaction with piperazine and a variety of aromatic aldehydes in the presence of acetic acid yielded the titled compounds (4a-4o). The structures of compounds wer

APA, Harvard, Vancouver, ISO, and other styles

17

Gehrmann, Robin, Tobias Hertlein, Elisa Hopke, Knut Ohlsen, Michael Lalk, and Andreas Hilgeroth. "Novel Small-Molecule Hybrid-Antibacterial Agents against S. aureus and MRSA Strains." Molecules 27, no. 1 (2021): 61. http://dx.doi.org/10.3390/molecules27010061.

Full text

Abstract:

Ongoing resistance developments against antibiotics that also affect last-resort antibiotics require novel antibacterial compounds. Strategies to discover such novel structures have been dimerization or hybridization of known antibacterial agents. We found novel antibacterial agents by dimerization of indols and hybridization with carbazoles. They were obtained in a simple one-pot reaction as bisindole tetrahydrocarbazoles. Further oxidation led to bisindole carbazoles with varied substitutions of both the indole and the carbazole scaffold. Both the tetrahydrocarbazoles and the carbazoles have

APA, Harvard, Vancouver, ISO, and other styles

18

Krucaite, Gintare, and Saulius Grigalevicius. "2,7(3,6)-Diaryl(arylamino)-substituted Carbazoles as Components of OLEDs: A Review of the Last Decade." Materials 14, no. 22 (2021): 6754. http://dx.doi.org/10.3390/ma14226754.

Full text

Abstract:

Organic light emitting diode (OLED) is a new, promising technology in the field of lighting and display applications due to the advantages offered by its organic electroactive derivatives over inorganic materials. OLEDs have prompted a great deal of investigations within academia as well as in industry because of their potential applications. The electroactive layers of OLEDs can be fabricated from low molecular weight derivatives by vapor deposition or from polymers by spin coating from their solution. Among the low-molar-mass compounds under investigation in this field, carbazole-based mater

APA, Harvard, Vancouver, ISO, and other styles

19

Gangadharan, Rajeswari, P. Narayanan, K. Sethusankar, Velu Saravanan, and Arasambattu K. Mohanakrishnan. "Crystal structures of three carbazole derivatives: 12-ethyl-7-phenylsulfonyl-7H-benzofuro[2,3-b]carbazole, (1), 2-(4,5-dimethoxy-2-nitrophenyl)-4-hydroxy-9-phenylsulfonyl-9H-carbazole-3-carbaldehyde, (2), and 12-phenyl-7-phenylsulfonyl-7H-benzofuro[2,3-b]carbazole, (3)." Acta Crystallographica Section E Crystallographic Communications 72, no. 12 (2016): 1744–50. http://dx.doi.org/10.1107/s2056989016016819.

Full text

Abstract:

The three title compounds, C26H19NO3S, (1), C27H20N2O8S, (2), and C30H19NO3S, (3), are carbazole derivatives, where (1) and (3) are heterocycle-containing carbazoles with a benzofuran moiety fused to a carbazole unit. In (2), a dimethoxynitrophenyl ring is attached to the carbazole moiety. In the three derivatives, a phenylsulfonyl group is attached to the N atom of the carbazole unit. Compound (1) crystallizes with two independent molecules in the asymmetric unit (AandB). The carbazole skeleton in the three compounds is essentially planar. In compound (1), the benzene ring of the phenylsulfon

APA, Harvard, Vancouver, ISO, and other styles

20

Golubeva, I. S., N. P. Yavorskaya, L. V. Ektova, et al. "ANTITUMOR ACTIVITY OF SOME DERIVATIVES OF INDOLO[2,3-A]CARBAZOLES N-GLYCOSIDES WITH XYLOSE CARBOHYDRATE RESIDUE." Russian Journal of Biotherapy 19, no. 4 (2020): 86–93. http://dx.doi.org/10.17650/1726-9784-2020-19-4-86-93.

Full text

Abstract:

Introduction. The search for new antineoplastic agents in a series of indolo[2,3-a]-carbazole derivatives is an urgent and promising direction, since compounds with antitumor activity have been found in this class. In the chemical fusion laboratory, N.N. Blokhin National Medical Research Center оf the Ministry of Health of Russia has developed an original and effective method for the synthesis of glycosides of indolo[2,3-a]-pyrrolo[3,4-c]carbazoles, which makes it possible to synthesize derivatives of N-glycosides of indolo[2,3-a]carbazoles with different substituents in the heterocyclic parts

APA, Harvard, Vancouver, ISO, and other styles

21

Dong, Xue Ming, Yue Zhi Cui, and Tian Duo Li. "Synthesis of Carbazole Modified Glass Plate for Detecting Nitroaromatic Compounds." Advanced Materials Research 557-559 (July 2012): 1074–77. http://dx.doi.org/10.4028/www.scientific.net/amr.557-559.1074.

Full text

Abstract:

A novel of carbazole derivatives containing –Si-OCH3 groups was successfully synthesized by reaction of carbazole with γ-chloropropylmethyldimethoxysilane. By immobilizing the carbazole derivatives on a glass plate surface through the chemical reaction of -Si-OCH3 and -Si-OH, a novel photoinduced luminescence film sensors was prepared. The structures of carbazole derivatives was determined by means of 1H NMR and the film was characterized by fluorescence measurements, contact angle, X-ray photoelectron spectroscopy. The sensing performance of the functionalized glass sensor has been evaluated.

APA, Harvard, Vancouver, ISO, and other styles

22

Krucaite, Gintare, and Saulius Grigalevicius. "Low Molar Mass Carbazole-Based Host Materials for Phosphorescent Organic Light-Emitting Diodes: A Review." Coatings 15, no. 4 (2025): 398. https://doi.org/10.3390/coatings15040398.

Full text

Abstract:

The second-generation phosphorescent organic light-emitting diodes are formed using phosphorescent emitters, which can theoretically achieve 100% internal quantum efficiency. However, these emitting materials usually suffer from triplet–triplet annihilation (TTA) and/or concentration-quenching effects. To address the disadvantages, host–guest systems are used in the emitting layer, where the guest is dispersed into a host matrix. Carbazole is one of the most commonly used electron-donating fragments, which is widely applied as a building block for the synthesis of the mentioned host materials.

APA, Harvard, Vancouver, ISO, and other styles

23

Niedziałkowska, Katarzyna, Aleksandra Felczak, Iwona E. Głowacka, Dorota G. Piotrowska, and Katarzyna Lisowska. "Antimicrobial Activity and Toxicity of Newly Synthesized 4-[4-(benzylamino)butoxy]-9H-carbazole Derivatives." International Journal of Molecular Sciences 24, no. 18 (2023): 13722. http://dx.doi.org/10.3390/ijms241813722.

Full text

Abstract:

One of the main challenges of medicinal chemistry is the search for new substances with antimicrobial potential that could be used in the fight against pathogenic microorganisms. Therefore, the antimicrobial activity of newly synthesized compounds is still being investigated. Carbazole-containing compounds appear to be promising antibacterial, antifungal, and antiviral agents. The aim of this study was to examine the antimicrobial potential and toxicity of newly synthesized isomeric fluorinated 4-[4-(benzylamino)butoxy]-9H-carbazole derivatives. Their antimicrobial activity against bacteria an

APA, Harvard, Vancouver, ISO, and other styles

24

Li, Liang, Yi Qun Wu, Chun Ying He, and Wu Biao Duan. "Preparation of Two Carbazole Derivatives and its Third-Order Nonlinear Optical Properties." Materials Science Forum 663-665 (November 2010): 231–34. http://dx.doi.org/10.4028/www.scientific.net/msf.663-665.231.

Full text

Abstract:

Carbazole derivative is one sort of important nonlinear optical materials. In this work, new symmetric-type D-π-D carbazole derivatives, 3, 6 - di- substituted carbazole chromophores with two styryl bridges of the two-dimensional conjugated D-π-D system were synthesized via Witting reaction and characterized by IR, NMR and MS. The third-order nonlinear optical properties of the material were investigated using single-beam Z-scan technique with Sapphire femtosecond laser pulses at 800nm, repetition rate of 1 KHz and pulse width of 140fs. The results of Z-scan with and without an aperture showed

APA, Harvard, Vancouver, ISO, and other styles

25

Bender, Matthias, and Jens Christoffers. "Investigations into the Regioselectivity of Fischer Indole and Friedländer Quinoline Syntheses with Octahydroisobenzofuran and Octahydroisoindole Derivatives." Zeitschrift für Naturforschung B 66, no. 12 (2011): 1209–18. http://dx.doi.org/10.1515/znb-2011-1203.

Full text

Abstract:

A Fischer indole synthesis with a cis-configurated octahydroisobenzofuran-6-one yielded exclusively a furo[3,4-c]carbazole derivative as the product of a regioselective angular annulation reaction. A Friedländer quinoline synthesis from the same substrate gave a mixture of angular and linear annulation products, i. e. furo[3,4-a]acridine and furo[3,4-b]acridine derivatives. When submitting a mixture of cis- and trans-octahydroisoindole derivatives to Fischer and Friedländer syntheses, the trans-starting material gave regioselectively linear annulation products, i. e. pyrrolo[3,4-b]carbazole an

APA, Harvard, Vancouver, ISO, and other styles

26

Beresneviciute, Raminta, Anil Kumar, Dovydas Blazevicius, et al. "Carbazolyl Electron Donor and Pyridinyl Electron Acceptor Containing Derivatives as Potential Host Materials for Green Organic Light-Emitting Diodes." Molecules 30, no. 9 (2025): 1911. https://doi.org/10.3390/molecules30091911.

Full text

Abstract:

Here, we present two series of new electroactive compounds containing electron donors (carbazolyl) and electron acceptor (pyridinyl) fragments as potential host materials. The objective compounds 9-(2-ethylhexyl)-3,6-di [3-(methoxypyridin-3-yl)carbazol-9-yl]carbazoles RB71 and RB74 were synthesized by an Ullmann coupling reaction between the intermediate derivatives: 9-(2-ethylhexyl)-3,6-diiodocarbazole and corresponding 3-(methoxypyridin-3-yl)-9H-carbazole. Other target derivatives, 9-alkyl-3-[N-(9-alkylcarbazol-3-yl)-N-(4-methylpyridin-2-yl)amino]carbazoles RB70 and RB75, were also prepared,

APA, Harvard, Vancouver, ISO, and other styles

27

Dufour, Fabien, and Gilbert Kirsch. "Carbazolo[2,1‐a]carbazole derivatives via fischer indole synthesis." Journal of Heterocyclic Chemistry 45, no. 1 (2008): 161–63. http://dx.doi.org/10.1002/jhet.5570450117.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Chen, Zheng, Jinfeng Chen, Xiaodong Wei, et al. "Antiviral Activities of Carbazole Derivatives against Porcine Epidemic Diarrhea Virus In Vitro." Viruses 13, no. 12 (2021): 2527. http://dx.doi.org/10.3390/v13122527.

Full text

Abstract:

Porcine epidemic diarrhea virus (PEDV), an enteric coronavirus, causes neonatal pig acute gastrointestinal infection with a characterization of severe diarrhea, vomiting, high morbidity, and high mortality, resulting in tremendous damages to the swine industry. Neither specific antiviral drugs nor effective vaccines are available, posing a high priority to screen antiviral drugs. The aim of this study is to investigate anti-PEDV effects of carbazole alkaloid derivatives. Eighteen carbazole derivatives (No.1 to No.18) were synthesized, and No.5, No.7, and No.18 were identified to markedly reduc

APA, Harvard, Vancouver, ISO, and other styles

29

Subhajit, Makar* Gargi Pal Pratap Chandra Pradhan Hemanta Kumar Khatua Paresh Kumar Roul. "Synthetic Advancement Of Carbazoles, Acting As Vibrant Platform In The Field Of Medicinal Chemistry." International Journal in Pharmaceutical Sciences 2, no. 8 (2024): 2888–99. https://doi.org/10.5281/zenodo.13292980.

Full text

Abstract:

Carbazole moiety is the key structural motif of many biologically active compounds including synthetic and natural products. Over the past several years, a large number of research highlighting the significance of carbazole derivatives has been reported in the literature. The present review focuses on the recent synthetic process, and their various biological properties of classical, tricyclic carbazole derivatives.

APA, Harvard, Vancouver, ISO, and other styles

30

Figueroa-Valverde, Lauro, Maria López-Ramos, Marcela Rosas-Nexticapa, et al. "Interaction of twenty-two carbazole derivatives with M1-muscarinic receptor using a theoretical model." Brazilian Journal of Science 3, no. 7 (2024): 26–37. http://dx.doi.org/10.14295/bjs.v3i7.573.

Full text

Abstract:

Several drugs have been used to treat asthma diseases, such as salmeterol, ipratropium bromide, montelukast, and fluticasone; however, some of these drugs can cause side effects such as hypokalemia, lactic acidosis, and hypotension. Analyzing these data, this study aimed to evaluate the possible interaction of twenty-two carbazole derivatives with the M1-muscrinic receptor to provide a new therapeutic alternative against asthma. The theoretical interaction of carbazole derivatives with M1-muscrinic receptor surface was determined using 5cxv protein, pirenzepine, atropine, AF-150, and PD159714

APA, Harvard, Vancouver, ISO, and other styles

31

Long, Solida, Joana B. Loureiro, Carla Carvalho, et al. "Semi-Synthesis of Small Molecules of Aminocarbazoles: Tumor Growth Inhibition and Potential Impact on p53." Molecules 26, no. 6 (2021): 1637. http://dx.doi.org/10.3390/molecules26061637.

Full text

Abstract:

The tumor suppressor p53 is inactivated by mutation in approximately 50% of human cancers. Small molecules that bind and stabilize those mutants may represent effective anticancer drugs. Herein, we report the tumor cell growth inhibitory activity of carbazole alkaloids and amino derivatives, as well as their potential activation of p53. Twelve aminocarbazole alkaloids were semi-synthesized from heptaphylline (1), 7-methoxy heptaphylline (2), and 7-methoxymukonal (3), isolated from Clausena harmandiana, using a reductive amination protocol. Naturally-occurring carbazoles 1–3 and their amino der

APA, Harvard, Vancouver, ISO, and other styles

32

Ibrayeva, Ayagoz, Urker Abibulla, Zulfiya Imanbekova, Bakhytzhan Baptayev, Robert J. O’Reilly, and Mannix P. Balanay. "Advancements in Carbazole-Based Sensitizers and Hole-Transport Materials for Enhanced Photovoltaic Performance." Molecules 29, no. 21 (2024): 5035. http://dx.doi.org/10.3390/molecules29215035.

Full text

Abstract:

Carbazole-based molecules play a significant role in dye-sensitized solar cells (DSSCs) due to their advantageous properties. Carbazole derivatives are known for their thermal stability, high hole-transport capability, electron-rich (p-type) characteristics, elevated photoconductivity, excellent chemical stability, and commercial availability. This review focuses on DSSCs, including their structures, working principles, device characterization, and the photovoltaic performance of carbazole-based derivatives. Specifically, it covers compounds such as 2,7-carbazole and indolo[3,2-b]carbazole, wh

APA, Harvard, Vancouver, ISO, and other styles

33

Khare, Ekta, Zeeshan Fatima, O. P. Tiwari, Jeevan Patra, and Unnati Kushavah. "Novel Carbazoles as AChE Inhibitors: Synthesis, Molecular Docking and Dynamic Simulation Studies." Asian Journal of Chemistry 36, no. 6 (2024): 1417–22. http://dx.doi.org/10.14233/ajchem.2024.31559.

Full text

Abstract:

Extensive exploration of N-substituted carbazole derivatives is underway as these compounds possess the therapeutic potential to address the neurological problems. The main aim of this study is to synthesize a series of N-substituted carbazole derivatives and investigate it’s in vitro and in silico ability to act as AChE inhibitors. The two-step synthesis was carried out that resulted in the development of novel carbazoles and then these were subsequently subjected to in vitro evaluation for acetylcholinesterase (AChE) inhibitory activity. Further to comprehend the binding interactions and est

APA, Harvard, Vancouver, ISO, and other styles

34

Taylor, J. W., C. P. Sloan, D. A. Holden, G. J. Kovacs, and R. O. Loutfy. "Synthesis and monolayer spreading behaviour of surface-active compounds containing electron- and hole-transporting groups. 2. Carbazole derivatives." Canadian Journal of Chemistry 67, no. 12 (1989): 2142–47. http://dx.doi.org/10.1139/v89-333.

Full text

Abstract:

The synthesis of several new surface-active carbazole derivatives is described. These compounds are intended to have applications as hole-transporting materials in thin-film devices assembled by the Langmuir–Blodgett technique. All of the carbazole-containing surfactants gave stable monolayers at the air–water interface with cross sections of 0.35–0.42 nm2/molecule, characteristic of the carbazole ring system oriented perpendicular to the surface with its long axis parallel to the surface. Conditions for Langmuir–Blodgett deposition of multilayers on titanium-coated polyester film were explore

APA, Harvard, Vancouver, ISO, and other styles

35

Liu, Siyang, Bryan Siu Ting Tam, Fanghao Ye та ін. "P‐14.10: Symmetric Carbazole‐Based Derivatives Realized Ultraviolet Emission by π‐Bridge Effect". SID Symposium Digest of Technical Papers 56, S1 (2025): 1710–12. https://doi.org/10.1002/sdtp.19193.

Full text

Abstract:

A series of symmetric carbazole derivatives were designed and synthesized. These compounds exhibited excellent thermal stabilities and ultraviolet light emission, which indicate the prepared carbazole derivatives will be potential candidates for realizing ultraviolet or near‐ ultraviolet emission.

APA, Harvard, Vancouver, ISO, and other styles

36

Taheri, B., M. Taghavi, M. Zarei, N. Chamkouri, and A. Mojaddami. "Imidazole and carbazole derivatives as potential anticancer agents: molecular docking studies and cytotoxic activity evaluation." Bulletin of the Chemical Society of Ethiopia 34, no. 2 (2020): 377–84. http://dx.doi.org/10.4314/bcse.v34i2.14.

Full text

Abstract:

Carbazoles and imidazole represent two important classes of heterocycles which exhibit diverse biological activities such as antitumor properties. In this study, imidazole (C1-C3) and carbazole (C4 and C5) derivatives were evaluated for their cytotoxic activity against three human cancer cell lines namely, MCF7 (human breast cancer), HT29 (human colon cancer), and HeLa (human cervical cancer). Carbazole derivatives (C4 and C5) with IC50 < 10 µM showed greater cytotoxic effect than imidazole derivatives (C1-C3). Furthermore, all compounds exhibited better anticancer activity against MCF-7 th

APA, Harvard, Vancouver, ISO, and other styles

37

Mahmoudi, Malek, Ervinas Urbonas, Dmytro Volyniuk, et al. "Indolocarbazoles with Sterically Unrestricted Electron-Accepting Anchors Showcasing Aggregation-Induced Thermally Activated Delayed Mechanoluminescence for Host-Free Organic Light-Emitting Diodes." Molecules 28, no. 16 (2023): 5999. http://dx.doi.org/10.3390/molecules28165999.

Full text

Abstract:

We investigated the effects of sterically nonrestricted electron-accepting substituents of three isomeric indolocarbazole derivatives on their aggregation-induced emission enhancement, mechanochromic luminescence and thermally activated delayed fluorescence. The compounds are potentially efficient emitters for host-free organic light-emitting diodes. The films of indolocarbazole derivatives exhibit emissions with wavelengths of fluorescence intensity maxima from 483 to 500 nm and photoluminescence quantum yields from 31 to 58%. The ionization potentials of the solid samples, measured by photoe

APA, Harvard, Vancouver, ISO, and other styles

38

Abonia, Rodrigo, Luisa F. Gutierrez, Angela T. Zwarycz, Sebastián Correa Smits, and Kenneth K. Laali. "An Efficient Selectfluor-Mediated Oxidative Thio- and Selenocyanation of Diversely Substituted Indoles and Carbazoles." Heteroatom Chemistry 2019 (January 2, 2019): 1–10. http://dx.doi.org/10.1155/2019/1459681.

Full text

Abstract:

A facile Selectfluor-mediated oxidative method for direct introduction of SCN and SeCN groups into diversely substituted indoles and carbazoles is described, by employing readily available thiocyanate and selenocyanate salts, and the scope of the method is underscored by providing 24 examples. The feasibility to sequentially introduce SCN followed by SeCN on a carbazole framework and to synthesize the corresponding S-tetrazole and Se-tetrazole derivatives is also demonstrated.

APA, Harvard, Vancouver, ISO, and other styles

39

Krawczyk, Przemysław, Beata Jędrzejewska, Klaudia Seklecka, Joanna Cytarska, and Krzysztof Z. Łączkowski. "Effect of the Chloro-Substitution on Electrochemical and Optical Properties of New Carbazole Dyes." Materials 14, no. 11 (2021): 3091. http://dx.doi.org/10.3390/ma14113091.

Full text

Abstract:

Carbazole derivatives are the structural key of many biologically active substances, including naturally occurring and synthetic ones. Three novel (E)-2-(2-(4-9H-carbazol-9-yl)benzylidene)hydrazinyl)triazole dyes were synthesized with different numbers of chlorine substituents attached at different locations. The presented research has shown the influence of the number and position of attachment of chlorine substituents on electrochemical, optical, nonlinear, and biological properties. The study also included the analysis of the use of the presented derivatives as potential fluorescent probes

APA, Harvard, Vancouver, ISO, and other styles

40

HWANG, EUN JEE, SANG HEE BAE, JI HOON LEE, TAE WAN KIM, and JONG WOOK PARK. "SYNTHESIS AND CHARACTERIZATION OF LONG-ALKYL CHAINED CARBAZOLE DERIVATIVES." Journal of Nonlinear Optical Physics & Materials 14, no. 04 (2005): 475–79. http://dx.doi.org/10.1142/s0218863505002918.

Full text

Abstract:

We have synthesized N-alkylated carbazole with a variation of alkyl size such as ethyl, hexyl, dodecyl and octadecyl group and have made thin film by using the spin-coating method. When N -octadecyl carbazole (NOC) film is made on ITO, the surface of the ITO/NOC layer becomes flatter compared to ITO and ITO/other N -alkylated carbazole layer. As the pendent alkyl chain length of carbazole becomes longer, the PL spectrum of the carbazole derivative becomes smooth and the PL maximum value is slightly shifted to long wavelength. ITO/NOC (100 nm)/ LiF (1 nm)/Al (200 nm) device showed typical I-V c

APA, Harvard, Vancouver, ISO, and other styles

41

Grande, Fedora, Giuseppina Ioele, Anna Caruso, et al. "Carbazoles: Role and Functions in Fighting Diabetes." Applied Sciences 13, no. 1 (2022): 349. http://dx.doi.org/10.3390/app13010349.

Full text

Abstract:

Carbazole derivatives have gained a lot of attention in medicinal chemistry over the last few decades due to their wide range of biological and pharmacological properties, including antibacterial, antitumor, antioxidant, and anti-inflammatory activities. The therapeutic potential of natural, semi-synthetic or synthetic carbazole-containing molecules has expanded considerably owing to their role in the pathogenesis and development of diabetes. Several studies have demonstrated the ability of carbazole derivatives to reduce oxidative stress, block adrenergic hyperactivation, prevent damage to pa

APA, Harvard, Vancouver, ISO, and other styles

42

Tavgeniene, Daiva, Raminta Beresneviciute, Dovydas Blazevicius, et al. "3-(N,N-Diphenylamino)carbazole Donor Containing Bipolar Derivatives with Very High Glass Transition Temperatures as Potential TADF Emitters for OLEDs." Coatings 12, no. 7 (2022): 932. http://dx.doi.org/10.3390/coatings12070932.

Full text

Abstract:

Well-defined electroactive bipolar derivatives of new structure have been synthesized from 3-(N,N-diphenylamino)-9H-carbazole and bis(4-fluorophenyl)sulfone, 4-fluorophenylsulfone or 4,4′-difluorobenzophenone, respectively. The full characterization of their structure is described. The amorphous materials with very high glass transition temperatures of 111–173 °C also possess high thermal stability, with onset decomposition temperatures of 351–398 °C. Some of the compounds having the best solubility were tested as the emitters dispersed in 4,4′-bis(N-carbazolyl)-1,1′-biphenyl (CBP) host for pr

APA, Harvard, Vancouver, ISO, and other styles

43

Nitin Kumar and Pallavi Manish Lavhale. "NSAID Carprofen Structure-based Derivatives as potential antibacterial agents." Asian Journal of Pharmaceutical Research and Development 12, no. 5 (2024): 52–58. http://dx.doi.org/10.22270/ajprd.v12i5.1478.

Full text

Abstract:

Drug repurposing (DR) is the use of existing drug in new alternative therapeutic role. Antibacterial perspective of non-antibiotic drugs includes NSAIDS are very useful to combat in a variety of infections in clinical practice. Carprofen (2-(6-chloro-9H-carbazol-2-yl)propanoic acid), is a NSAIDS category drug based on potential pharmacophore tricyclic carbazole nucleus, now commonly used in veterinary medicine. This carprofen drug is used in osteoarthritis and postoperative pain in dogs. Around the worldwide, researchers’ significantly revealed drug repurposing role of carprofen structure-base

APA, Harvard, Vancouver, ISO, and other styles

44

Zawadzka, Katarzyna, Aleksandra Felczak, Iwona E. Głowacka, Dorota G. Piotrowska, and Katarzyna Lisowska. "Evaluation of the Antimicrobial Potential and Toxicity of a Newly Synthesised 4-(4-(Benzylamino)butoxy)-9H-carbazole." International Journal of Molecular Sciences 22, no. 23 (2021): 12796. http://dx.doi.org/10.3390/ijms222312796.

Full text

Abstract:

One of the greatest threats to human and animal health is posed by infections caused by drug-resistant bacterial strains. Therefore, newly synthesised substances are tested for their antimicrobial activity. Carbazole derivatives seem to be promising antibacterial agents. This study aimed at investigating the toxicity and activity of newly synthesised, functionalised carbazole derivative 2 (4-(4-(benzylamino)butoxy)-9H-carbazole) against various microorganisms. Its antimicrobial potential against Gram-positive and Gram-negative bacteria, yeast, and filamentous fungi was examined according to CL

APA, Harvard, Vancouver, ISO, and other styles

45

Nitin Kumar, Vishal Nemaysh, and Pratibha Mehta Luthra. "Synthesis and anticancer activity evaluation of substituted carbazole bearing thiosemicarbazide derivatives against human glioma U87 MG cell line." World Journal of Advanced Research and Reviews 16, no. 3 (2022): 884–92. http://dx.doi.org/10.30574/wjarr.2022.16.3.1402.

Full text

Abstract:

Both carbazole and thiosemicarbazide scaffold showed various potential biological activities in medicinal chemistry. In this research work, we synthesized a series of carbazole bearing thiosemicarbazide derivatives (17-28) and evaluated thier in vitro cytotoxicity (IC50) profile on the U87 MG cell line using MTT assay. All target compounds were well characterized by NMR and HRMS mass spectroscopy. In series, six compounds (17, 20, 21, 22, 23, 28) found better in vitro cytotoxicity (IC50) values were 26.50 µM, 34.0 µM, 39 µM, 80 µM, 62 µM, 50 µM respectively compare to standard drug Temozolomid

APA, Harvard, Vancouver, ISO, and other styles

46

Gümrükçüoğlu, Nurhan, and Bahar Bilgin Sökmen. "Synthesis of oxadiazole substituted new carbazole derivatives as antioxidant and antiurease agent." European Journal of Biological Research 12, no. 2 (2022): 181–89. https://doi.org/10.5281/zenodo.6612440.

Full text

Abstract:

Heterocyclic compounds containing nitrogen together with an oxygen atom in their structures are an important class of medicinal chemistry compounds due to their interesting diverse biological applications. Some compounds including carbazole ring, which are aromatic organic compounds in tricyclic structure, show biological activity in a wide spectrum. Oxadiazole compounds attract the attention of many chemists thanks to their antibacterial, antitumor, anticancer, anti-viral, antimicrobial, anti-HIV, antituberculosis and antioxidant properties. In this study, new oxadiazole substituted carbazole

APA, Harvard, Vancouver, ISO, and other styles

47

Yu, Bo, Ping Xu, Shanshan Zhu, et al. "Selective Biodegradation of S and N Heterocycles by a Recombinant Rhodococcus erythropolis Strain Containing Carbazole Dioxygenase." Applied and Environmental Microbiology 72, no. 3 (2006): 2235–38. http://dx.doi.org/10.1128/aem.72.3.2235-2238.2006.

Full text

Abstract:

ABSTRACT The carbazole dioxygenase genes were introduced into a dibenzothiophene degrader. The recombinant Rhodococcus erythropolis SN8 was capable of efficiently degrading dibenzothiophene and carbazole simultaneously. SN8 could also degrade various alkylated derivatives of carbazole and dibenzothiophene in FS4800 crude oil by just a one-step bioprocess.

APA, Harvard, Vancouver, ISO, and other styles

48

Yang, Chao, Kai Lin, Lan Huang, Wei-dong Pan, and Sheng Liu. "Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization." Beilstein Journal of Organic Chemistry 12 (November 22, 2016): 2490–94. http://dx.doi.org/10.3762/bjoc.12.243.

Full text

Abstract:

A rapid and efficient route has been developed for the synthesis of 9-methoxycarbonylindolo[3,2-a]carbazole derivatives. The key steps in this approach involved an aromatic amination and an oxidative biaryl coupling. Via the present route, indolo[3,2-a]carbazole derivatives are available in 3–4 steps based on commercially available starting materials.

APA, Harvard, Vancouver, ISO, and other styles

49

Gao, Wentao, Meiru Zheng, and Yang Li. "A novel and facile synthesis of 3-(2-benzofuroyl)- and 3,6-bis(2-benzofuroyl)carbazole derivatives." Beilstein Journal of Organic Chemistry 7 (November 17, 2011): 1533–40. http://dx.doi.org/10.3762/bjoc.7.180.

Full text

Abstract:

A facile synthesis of hitherto unreported 3-(2-benzofuroyl)carbazoles 3a–k, 3,6-bis(2-benzofuroyl)carbazoles 5a–k, and naphtho[2,1-b]furoylcarbazoles 3l and 5l is described. The synthesis mainly relies on the ultrasound-assisted Rap–Stoermer reaction of 3-chloroacetyl- (1) or 3,6-dichloroacetyl-9-ethyl-9H-carbazole (4) with various salicylaldehydes 2a–k as well as 2-hydroxy-1-naphthaldehyde (2l) in CH3CN with the presence of PEG-400 as catalyst. The procedure offers easy access to benzofuroylcarbazoles in short reaction times and the products are obtained in moderate to good yields.

APA, Harvard, Vancouver, ISO, and other styles

50

Ceramella, Jessica, Domenico Iacopetta, Anna Caruso, et al. "5,8-Dimethyl-9H-carbazole Derivatives Blocking hTopo I Activity and Actin Dynamics." Pharmaceuticals 16, no. 3 (2023): 353. http://dx.doi.org/10.3390/ph16030353.

Full text

Abstract:

Over the years, carbazoles have been largely studied for their numerous biological properties, including antibacterial, antimalarial, antioxidant, antidiabetic, neuroprotective, anticancer, and many more. Some of them have gained great interest for their anticancer activity in breast cancer due to their capability in inhibiting essential DNA-dependent enzymes, namely topoisomerases I and II. With this in mind, we studied the anticancer activity of a series of carbazole derivatives against two breast cancer cell lines, namely the triple negative MDA-MB-231 and MCF-7 cells. Compounds 3 and 4 wer

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!