Academic literature on the topic 'Carbocyclic'

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Journal articles on the topic "Carbocyclic"

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Murarka, Sandip, and Andrey Antonchick. "Metal-Catalyzed Oxidative Coupling of Ketones and Ketone Enolates." Synthesis 50, no. 11 (2018): 2150–62. http://dx.doi.org/10.1055/s-0037-1609715.

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Recent years have witnessed a significant advancement in the field of radical oxidative coupling of ketones towards the synthesis of highly useful synthetic building blocks, such as 1,4-dicarbonyl compounds, and biologically important heterocyclic and carbocyclic compounds. Besides oxidative homo- and cross-coupling of enolates, other powerful methods involving direct C(sp3)–H functionalizations of ketones­ have emerged towards the synthesis of 1,4-dicarbonyl compounds. Moreover, direct α-C–H functionalization of ketones has also allowed an efficient access to carbocycles and heterocycles. Thi
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Yuasa, Hideya, Monica M. Palcic та Ole Hindsgaul. "Synthesis of the carbocyclic analog of uridine 5′-(α-D-galactopyranosyl diphosphate) (UDP-Gal) as an inhibitor of β(1 → 4)-galactosyltransferase". Canadian Journal of Chemistry 73, № 12 (1995): 2190–95. http://dx.doi.org/10.1139/v95-272.

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Uridine 5′-(5a-carba-α-D-galactopyranosyl diphosphate), the carbocyclic analog of UDP-galactose where the ring oxygen of the galactose residue is replaced by a methylene group, was chemically synthesized as a potential inhibitor of galactosyltransferases. It was found to be a competitive inhibitor of UDP-galactose: N-acetylglucosamine β(1 → 4)-galactosyltransferase from bovine milk (EC 2.4.1.22) with a Ki value of 58 µM, similar to the Km value for UDP-galactose (25 µM). Keywords: carbocycles, UDP-5a-carbagalactose, galactosyltransferase, glycosyltransferase inhibitor.
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Aimon, Anthony, Louis J. Farrugia, and J. Stephen Clark. "Synthesis of the Core Framework of the Cornexistins by Intramolecular Nozaki-Hiyama-Kishi Coupling." Molecules 24, no. 14 (2019): 2654. http://dx.doi.org/10.3390/molecules24142654.

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A new and direct approach to the construction of the core framework of the herbicidal natural products cornexistin and hydroxycornexistin has been developed. Formation of the nine-membered carbocycle found in the natural products has been accomplished by an intramolecular Nozaki-Hiyama-Kishi reaction between a vinylic iodide and an aldehyde. Good yields of carbocyclic products were obtained from the reaction, but diastereomeric mixtures of allylic alcohols were produced. The cyclisation reaction was successful irrespective of the relative configuration of the stereogenic centres in the cyclisa
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Meier, Chris, Simon Weising, and Ilaria Torquati. "Stereoselective Synthesis of 1′,2′-cis-Disubstituted Carbocyclic ribo-Nucleoside Analogues." Synthesis 50, no. 06 (2017): 1264–74. http://dx.doi.org/10.1055/s-0036-1591732.

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Herein we disclose an efficient strategy for the convergent synthesis of 1′,2′-cis-disubstituted carbocyclic ribo-nucleoside analogues. Starting from an enantiomerically pure cyclopentenol precursor, the key step for the preparation of the highly functionalized carbocyclic building block is an asymmetric dihydroxylation. Employing different variants of the Mitsunobu protocol, the condensation with all-natural nucleobases or their precursors affords a series of ribo-configured carbocyclic 1′,2′-cis-disubstituted nucleoside analogues.
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Yin, Xueqiang, Guoxia Zhao, and Stewart W. Schneller. "Carbocyclic sinefungin." Tetrahedron Letters 48, no. 28 (2007): 4809–11. http://dx.doi.org/10.1016/j.tetlet.2007.05.079.

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Marquez, Victor E., and Mu-Ill Lim. "Carbocyclic nucleosides." Medicinal Research Reviews 6, no. 1 (1986): 1–40. http://dx.doi.org/10.1002/med.2610060102.

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Liu, Peng, and Chung K. Chu. "Enantiomeric synthesis of carbocyclic analogs of D- and L-6-azapyrimidine ribonucleosides." Canadian Journal of Chemistry 84, no. 4 (2006): 748–54. http://dx.doi.org/10.1139/v06-052.

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An effective and practical synthesis of carbocyclic D- and L-6-azapyrimidine nucleosides (3–8) was described. Starting from D-ribose, a new efficient methodology for the synthesis of L-2,3-O-cyclohexylidene-4-cyclopentenone (23) was developed via a ring-closing metathesis, which was applied for the synthesis of L-cyclopentyl-6-azapyrimidine nucleosides (6–8). The regiospecific introduction of 6-azauracil on the carbocyclic moiety (9 and 25) was also achieved by masking its N3 position with a 4-methylthio group.Key words: carbocyclic nucleosides, 6-azapyrimidine nucleosides, enantiomeric synthe
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Vince, Robert, Mei Hua, and Carol A. Caperelli. "PHOSPHONATE ANALOGS OF CARBOCYCLIC PHOSPHORIBOSYLAMINE AND CARBOCYCLIC GLYCINAMIDE RIBONUCLEOTIDE." Nucleosides and Nucleotides 15, no. 11-12 (1996): 1711–18. http://dx.doi.org/10.1080/07328319608002726.

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Slama, James T., Nimish Mehta та Ewa Skrzypczak-Jankun. "Carbocyclic Ribosylamines: Synthesis of 5-Substituted Carbocyclic β-Ribofuranosylamines". Journal of Organic Chemistry 71, № 20 (2006): 7877–80. http://dx.doi.org/10.1021/jo060920l.

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Zard, Samir Z. "The xanthate route to six-membered carbocycles." Journal of Chemical Research 46, no. 2 (2022): 174751982210881. http://dx.doi.org/10.1177/17475198221088194.

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Convergent routes to various six-membered carbocyclic architectures exploiting the unique radical chemistry of xanthates are described in this brief review. Three approaches are discussed. The first is the modification of existing cyclohexane building blocks, namely, cyclohexanones, cyclohexenones and cyclohexenes. The second deals with the construction of six-membered carbocycles by associating the chemistry of xanthates with classical ionic reactions, especially the Robinson annulation, the Michael addition and the Horner–Wadsworth–Emmons condensation. Finally, the third route is the formati
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Dissertations / Theses on the topic "Carbocyclic"

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Phun, Lien Hoang. "Innovative approaches to carbocyclic and heterocyclic compounds using strained carbocycles." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/47542.

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Natural products and small molecules play a major role in drug development. However, using natural products as a source of medicine comes with many challenges, such as lack of natural abundance and difficulty in isolation. Consequently, synthetic organic chemistry is a solution in order to access these compounds in usable quantities. However, synthetic chemisty comes with its own challenges such as efficiency, chemoselectivity, stereoselectivity and enantioselectivity. Therefore, synthetic tools that addresses these challenges are required solve these limitations. This thesis discusses new met
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Das, Jayanta. "Trans formative reactions on carbocyclic compounds." Thesis, University of North Bengal, 2015. http://ir.nbu.ac.in/handle/123456789/1863.

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Finniear, Aled. "Asymmetric synthesis of chiral carbocyclic nucleosides." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283609.

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Agathocleous, D. C. "Synthesis of carbocyclic analogues of penicillin." Thesis, University of Huddersfield, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304428.

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Palmer, Christopher Francis. "Synthesis of carbocyclic analogues of clitocine." Thesis, University of Exeter, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277146.

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Hunt, Peter Alan. "Carbocyclic analogues of nikkomycins and polyoxins." Thesis, Imperial College London, 1989. http://hdl.handle.net/10044/1/47482.

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Standen, Patricia E. "Metathesis routes to carbocyclic frame works." Thesis, Loughborough University, 2013. https://dspace.lboro.ac.uk/2134/13204.

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The addition of allyl magnesium and allyl indium reagents to a key TBS protected norbornenyl building block, synthesised in 6-steps from commercially available 1,1-dimethoxy-2,3,4,5-tetrachlorocyclo-pentadiene, has been achieved providing the syn addition products with high diastereoselectivity. The subsequent exposure of the addition products to metathesis conditions, in the presence of ethylene, then provided cis fused [3.0.3]-carbocycles with very high regioselectivity, via a Ring Rearrangement Metathesis (RRM) transformation. The high level of regioselectivity is due to the rearrangement o
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Dossett, David Lawrence. "Alternatives to [4+1] carbocyclic annulations." Thesis, Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/101269.

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6-Carboethoxybicyclo [3.3.0] oct-6-en-2-one has been prepared by the intramolecular [4+1] cyclopentene annulation method. This compound and its precursor, 6-vinyl-6-carboethoxybicyclo[3.1.0]hexan-2-one were attained as the necessary standards for the investigation of the course of intramolecular Michael addition-alkylation sequence of l-phenylsulfonyl-6-carboethoxyocta-5,7-dien-2-one.<br>M.S.
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He, Mingzhu Schneller Stewart W. "Carbocyclic C-nucleosides derived from formycin." Auburn, Ala, 2008. http://hdl.handle.net/10415/1427.

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Ghosh, Pranab. "Studies on chemical reactions of carbocyclic compounds." Thesis, University of North Bengal, 1991. http://hdl.handle.net/123456789/767.

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Books on the topic "Carbocyclic"

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Lloyd, Douglas, ed. Topics in Carbocyclic Chemistry. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4684-8270-6.

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Agrofoglio, L. A., and S. R. Challand. Acyclic, Carbocyclic and L-Nucleosides. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-007-0816-7.

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Li, Jie Jack, ed. Name Reactions for Carbocyclic Ring Formations. John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470872215.

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Jack, Li Jie, ed. Name reactions for carbocyclic ring formations. Wiley, 2010.

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1936-, Ōsawa Eiji, and Yonemitsu Osamu 1930-, eds. Carbocyclic cage compounds: Chemistry and applications. VCH, 1992.

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Hay, Philip A. The design and synthesis of novel carbocyclic transition-state analogues of glycoside hydrolysis. UMIST, 1997.

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Carbocycle construction in terpene synthesis. VCH, 1988.

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The chemistry of conjugated cyclic compounds: To be or not to be like benzene? Wiley, 1989.

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Culshaw, Andrew James. Intramolecular cycloadditions of carbonyl oxides to alkenes: A new approach to oxygenated carbocycles. University of Salford, 1989.

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Stansfield, Kevin. Diels-alder reactions of fluoroalkenes: New strategy and tactics in the synthesis of fluorinated carbocycles. University of Birmingham, 1996.

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Book chapters on the topic "Carbocyclic"

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Thummel, R. P. "Carbocyclic Annelated Pyridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186701.ch2.

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Agrofoglio, L. A., and S. R. Challand. "The chemistry of carbocyclic nucleosides." In Acyclic, Carbocyclic and L-Nucleosides. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-007-0816-7_4.

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Agrofoglio, L. A., and S. R. Challand. "Biological activity of carbocyclic nucleosides." In Acyclic, Carbocyclic and L-Nucleosides. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-007-0816-7_5.

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Kiss, Loránd, Enik˝ Forró, and Ferenc Fülöp. "Synthesis of Carbocyclic β-Amino Acids." In Amino Acids, Peptides and Proteins in Organic Chemistry. Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527631766.ch8.

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Agrofoglio, L. A., and S. R. Challand. "General introduction." In Acyclic, Carbocyclic and L-Nucleosides. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-007-0816-7_1.

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Agrofoglio, L. A., and S. R. Challand. "The chemistry of acyclic nucleosides." In Acyclic, Carbocyclic and L-Nucleosides. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-007-0816-7_2.

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Agrofoglio, L. A., and S. R. Challand. "Biological activity of acyclonucleosides." In Acyclic, Carbocyclic and L-Nucleosides. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-007-0816-7_3.

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Agrofoglio, L. A., and S. R. Challand. "The chemistry of L-nucleosides." In Acyclic, Carbocyclic and L-Nucleosides. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-007-0816-7_6.

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Agrofoglio, L. A., and S. R. Challand. "Anti-viral activities of L-nucleosides." In Acyclic, Carbocyclic and L-Nucleosides. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-007-0816-7_7.

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Leclerc, E. "Chemical Synthesis of Carbocyclic Analogues of Nucleosides." In Chemical Synthesis of Nucleoside Analogues. John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118498088.ch12.

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Conference papers on the topic "Carbocyclic"

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Šála, Michal, Hubert Hřebabecký, Milena Masojídková, and Antonín Holý. "Synthesis of novel racemic conformationally locked carbocyclic nucleosides." In XIIIth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2005. http://dx.doi.org/10.1135/css200507461.

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Mackman, R. L., C. G. Boojamra, J. Chen, et al. "Synthesis and antiviral activity of 4'-modified carbocyclic nucleoside phosphonates (CNPs)." In XIVth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2008. http://dx.doi.org/10.1135/css200810191.

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Dejmek, Milan, Hubert Hřebabecký, Michal Šála, Martin Dračínský, and Radim Nencka. "Synthesis of conformationally locked carbocyclic nucleosides with norbornane as pseudosugar moiety." In XVth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201112208.

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Margetic, Davor, Ronald Warrener, Guangxing Sun, and Douglas Butler. "The Preparation of 7-Substituted Norbornadiene-2,3-dicarboxylic Anhydrides and a Theoretical and Experimental Study of their Thermolysis to 5-Membered Carbocyclic or Heterocyclic Anhydrides." In The 10th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2006. http://dx.doi.org/10.3390/ecsoc-10-01397.

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Kadikova, Gulnara N., and Usein M. Dzhemilev. "New in the Catalytic Synthesis of Practically Important Eight- and Nine-Membered Carbocycles by Cycloaddition Reactions with the Participation of 1,3,5-Cycloheptatrienes and 1,3,5,7-Cyclooctatetraenes." In ECCS 2021. MDPI, 2021. http://dx.doi.org/10.3390/eccs2021-11037.

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Reports on the topic "Carbocyclic"

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Secrist, John A., and III. Synthesis of Carbocyclic 3-Deazaadenosine Analogs as Potential Agents Against Poxvirus. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada396210.

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Huang, Qinhua. New Palladium-Catalyzed Approaches to Heterocycles and Carbocycles. Office of Scientific and Technical Information (OSTI), 2004. http://dx.doi.org/10.2172/835382.

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