Relevant bibliographies by topics / Carbohydrate drugs

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Carbohydrate drugs'

Author: Grafiati
Published: 4 June 2021
Last updated: 24 January 2023

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Journal articles on the topic "Carbohydrate drugs"

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Witczak, Zbigniew J. "Carbohydrates as Drugs and Potential Therapeutics." Current Medicinal Chemistry 1, no. 5 (1995): 392–405. http://dx.doi.org/10.2174/092986730105220216103120.

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Abstract: New developments in the medidnal chemistry of carbohydrate based drugs is presented. Classificatio!"J,_ as well as therapeutic effects and potential applications are discussed. The main objective of this review is to compile literature data on known carbohydrate therapeutics and address a new developments in particularly promising areas of medicinal chemistry utilizing carbohydrates as new potential drugs.
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Pieters, Roland J. "Toward multivalent carbohydrate drugs." Drug Discovery Today: Technologies 6, no. 1-4 (2009): e27-e31. http://dx.doi.org/10.1016/j.ddtec.2009.12.001.

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Johnson, M. A., and B. M. Pinto. "Molecular Mimicry of Carbohydrates by Peptides." Australian Journal of Chemistry 55, no. 2 (2002): 13. http://dx.doi.org/10.1071/ch02047.

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The use of carbohydrates as drugs and vaccines has several limitations. Molecular mimics of carbohydrates provide an alternative source of compounds to target pathways involving protein-carbohydrate interactions. In recent years, immunological studies have demonstrated the ability of certain peptides to act as molecular mimics of carbohydrates, in that they are able to induce an anti-carbohydrate immune response. Carbohydrate-mimetic peptides that bind to enzymes and lectins have also been discovered. The nature of this mimicry at the molecular level is currently the subject of investigation. Structural data regarding the origin of mimicry are reviewed, and their implications for drug and vaccine design are presented.
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Ernst, Beat, and John L. Magnani. "From carbohydrate leads to glycomimetic drugs." Nature Reviews Drug Discovery 8, no. 8 (2009): 661–77. http://dx.doi.org/10.1038/nrd2852.

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Witczak, Zbigniew J. "Thio Sugars: Biological Relevance as Potential New Therapeutics." Current Medicinal Chemistry 6, no. 2 (1999): 165–78. http://dx.doi.org/10.2174/0929867306666220207213740.

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Abstract: The biological relevance of sulfur containing carbohydrates is gaining substantial attention. Thus the new developments, especially in the synthetic and medicinal chemistry of thio-sugars are critically important for carbohydrate drug design. New studies of biological processes including bio­ synthetic reactions and enzyme control mechanisms, discovered during the last few years clearly contributed to an understanding of their biological roles. These roles of carbohydrates and thio­ sugars in particular through biological processes and diseases are becoming better understood now. These new trends will provide tremendous opportunities for the development of carbohydrates as new potential drugs. The main objective of this article is to address these new promising advances and stimulate continuous development of carbohydrate pharmaceuticals.
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Zhang, Yan, and Fengshan Wang. "Carbohydrate drugs: current status and development prospect." Drug Discoveries & Therapeutics 9, no. 2 (2015): 79–87. http://dx.doi.org/10.5582/ddt.2015.01028.

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MCAULIFFE, J. C., and O. HINDSGAUL. "ChemInform Abstract: Carbohydrate Drugs-An Ongoing Challenge." ChemInform 28, no. 29 (2010): no. http://dx.doi.org/10.1002/chin.199729272.

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Horne, Graeme. "Correcting Nature: Targeting dysfunctional carbohydrate processing." Biochemist 34, no. 1 (2012): 26–31. http://dx.doi.org/10.1042/bio03401026.

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The pharmaceutical industry has experienced remarkable growth over the last few decades fuelled by sales revenues of blockbuster drugs such as Lipitor® (Pfizer), Plavix® (BMS/Sanofi-Aventis) and Advair® (GlaxoSmithKline). However, as these drugs approach patent expiries, the era of the blockbuster drug can be considered to be coming to an end.
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Lee, Gregory, Cheng-Yuan Huang, Song-Nan Chow, and Chin-Hsiang Chien. "Carbohydrate-associated epitope-based anti-cancer drugs and vaccines." Advances in Bioscience and Biotechnology 04, no. 09 (2013): 18–23. http://dx.doi.org/10.4236/abb.2013.49a003.

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YIN, Jian. "Chemical glycobiology drives the discovery of carbohydrate-based drugs." Chinese Journal of Natural Medicines 18, no. 10 (2020): 721–22. http://dx.doi.org/10.1016/s1875-5364(20)60011-5.

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Dissertations / Theses on the topic "Carbohydrate drugs"

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Basu, Sarkar Arindam Kochak Gregory Michael. "Carbohydrate nanoparticles a novel drug delivery platform for the systemic route /." Auburn, Ala., 2006. http://repo.lib.auburn.edu/2006%20Summer/Dissertations/BASU_SARKAR_26.pdf.

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Umesiri, Francis E. "Synthesis of Carbohydrate-based Inhibitors of Antigen 85." University of Toledo / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1282006047.

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Lawton, Clare Louise. "Investigation of the action of serotoninergic drugs on carbohydrate intake in the rat." Thesis, University of Leeds, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293692.

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Ross, Benjamin Paul. "Lipoamino acid- and carbohydrate- based penetration enhancers for use in oral drug delivery /." [St. Lucia, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18165.pdf.

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Mendlik, Matthew T. "Syntheses and investigations of 2,6-dideoxysugars contained in diverse bioactive compounds." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1120673161.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from second page of PDF file. Document formatted into pages; contains xix, 347 p.; also includes graphics. Includes bibliographical references (p. 183-192). Available online via OhioLINK's ETD Center
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Sommer, Roman [Verfasser]. "Pseudomonas aeruginosa Lectin LecB as a Target in the Anti-Virulence Therapy : Towards Carbohydrate-based Anti-Adhesion Drugs / Roman Sommer." Konstanz : Bibliothek der Universität Konstanz, 2016. http://d-nb.info/1160876479/34.

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Black, Richard Neil Alexander. "On the interaction of lipid and glucose metabolism : the effect of hypolipidaemic drugs and dietary carbohydrate manipulation on insulin resistance." Thesis, Queen's University Belfast, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.479278.

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Lundborg, Magnus. "Computer-Assisted Carbohydrate Structural Studies and Drug Discovery." Doctoral thesis, Stockholms universitet, Institutionen för organisk kemi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-56411.

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Carbohydrates are abundant in nature and have functions ranging from energy storage to acting as structural components. Analysis of carbohydrate structures is important and can be used for, for instance, clinical diagnosis of diseases as well as in bacterial studies. The complexity of glycans makes it difficult to determine their structures. NMR spectroscopy is an advanced method that can be used to examine carbohydrates at the atomic level, but full assignments of the signals require much work. Reliable automation of this process would be of great help. Herein studies of Escherichia coli O-antigen polysaccharides are presented, both a structure determination by NMR and also research on glycosyltransferases which assemble the polysaccharides. The computer program CASPER has been improved to assist in carbohydrate studies and in the long run make it possible to automatically determine structures based only on NMR data. Detailed computer studies of glycans can shed light on their interactions with proteins and help find inhibitors to prevent unwanted binding. The WaaG glycosyltransferase is important for the formation of E. coli lipopolysaccharides. Molecular docking analyses of structures confirmed to bind this enzyme have provided information on how inhibitors could be composed. Noroviruses cause gastroenteritis, such as the winter vomiting disease, after binding human histo-blood group antigens. In one of the projects, fragment-based docking, followed by molecular dynamics simulations and binding free energy calculations, was used to find competitive binders to the P domain of the capsid of the norovirus VA387. These novel structures have high affinity and are a very good starting point for developing drugs against noroviruses. The protein targets in these two projects are carbohydrate binding, but the techniques are general and can be applied to other research projects.<br>At the time of the doctoral defense, the following papers were unpublished and had a status as follows: Paper 4: Submitted. Paper 5: Manuscript. Paper 6. Manuscript.
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Probert, John Michael. "Functional nano-particles derived from dendrimer derivatisation and self-assembly." Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266664.

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Varela, Aramburu Silvia [Verfasser]. "Carbohydrate-based Nanomaterials for Imaging and Drug Delivery / Silvia Varela Aramburu." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/117663254X/34.

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Books on the topic "Carbohydrate drugs"

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A, Klesov A., Witczak Zbigniew J. 1947-, and Platt David 1953-, eds. Carbohydrate drug design. American Chemical Society, 2006.

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1952-, Roy René, American Chemical Society. Division of Carbohydrate Chemistry., and American Chemical Society Meeting, eds. Carbohydrate-based vaccines. American Chemical Society, 2008.

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1947-, Witczak Zbigniew J., and Nieforth Karl A, eds. Carbohydrates in drug design. M. Dekker, 1997.

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Klesov, A. A. Glycobiology and drug design. Edited by American Chemical Society. Division of Carbohydrate Chemistry. American Chemical Society, 2012.

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Tang lei yao wu he cheng yu zhi bei: Synthesis and preparation of carbohydrate-based drug. Hua xue gong ye chu ban she, 2010.

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Klesov, A. A. Glycobiology and drug design. Edited by American Chemical Society. Division of Carbohydrate Chemistry. American Chemical Society, 2012.

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Edgar, Kevin J., Charles M. Buchanan, and Thomas Heinze. Polysaccharide materials: Performance by design. American Chemical Society, 2009.

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Edgar, Kevin J. Polysaccharide materials: Performance by design. American Chemical Society, 2009.

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Edgar, Kevin J. Polysaccharide materials: Performance by design. American Chemical Society, 2009.

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Seeberger, Peter H., and Christoph Rademacher, eds. Carbohydrates as Drugs. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-08675-0.

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Book chapters on the topic "Carbohydrate drugs"

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Mühlebach, Stefan, and Beat Flühmann. "Iron Carbohydrate Complexes: Characteristics and Regulatory Challenges." In Non-Biological Complex Drugs. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-16241-6_5.

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Dalmo, R. "Immunostimulatory β(1,3)-D-glucans; prophylactic drugs against threatening infectious diseases of fish." In Bioactive Carbohydrate Polymers. Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-015-9572-8_8.

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Zopf, D., P. Simon, R. Barthelson, Diana Cundell, I. Idanpaan-Heikkila, and E. Tuomanen. "Development of Anti-Adhesion Carbohydrate Drugs for Clinical Use." In Toward Anti-Adhesion Therapy for Microbial Diseases. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0415-9_4.

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Frank, Martin. "Computational Docking as a Tool for the Rational Design of Carbohydrate-Based Drugs." In Topics in Medicinal Chemistry. Springer International Publishing, 2014. http://dx.doi.org/10.1007/7355_2014_42.

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Petitou, M. "Drugs Based on Carbohydrates." In Synthetic Oligosaccharides. American Chemical Society, 1994. http://dx.doi.org/10.1021/bk-1994-0560.ch002.

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Kiso, Makoto, Hideharu Ishida, and Hiromune Ando. "Complex Carbohydrate Synthesis." In Carbohydrate-Based Drug Discovery. Wiley-VCH Verlag GmbH & Co. KGaA, 2005. http://dx.doi.org/10.1002/3527602437.ch2.

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Suter, P. M. "Carbohydrates and Dietary Fiber." In Atherosclerosis: Diet and Drugs. Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/3-540-27661-0_8.

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Saeidnia, Soodabeh. "Carbohydrates Against Cancer." In New Approaches to Natural Anticancer Drugs. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-14027-8_6.

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Keding, Stacy J., and Samuel J. Danishefsky. "Synthetic Carbohydrate-Based Vaccines." In Carbohydrate-Based Drug Discovery. Wiley-VCH Verlag GmbH & Co. KGaA, 2005. http://dx.doi.org/10.1002/3527602437.ch14.

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Klyosov, Anatole A. "Carbohydrates and Drug Design." In ACS Symposium Series. American Chemical Society, 2012. http://dx.doi.org/10.1021/bk-2012-1102.ch001.

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Conference papers on the topic "Carbohydrate drugs"

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Altamore, Timothy M., Peter J. Duggan, and Guy Y. Krippner. "IMPROVING THE MEMBRANE PERMEABILITY OF CARBOHYDRATE BASED DRUGS." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.492.

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Altamore, Timothy M., Peter J. Duggan, and Guy Y. Krippner. "IMPROVING THE MEMBRANE PERMEABILITY OF CARBOHYDRATE BASED DRUGS." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.661.

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Roger, Olivier, Sylvia Colliec-Jouault, Sabine Matou, et al. "A MODIFIED BACTERIAL EXOPOLYSACCHARIDE: A NEW SOURCE OF HEPARIN-LIKE DRUGS." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.432.

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Suzuki, Yasuo, Takashi Suzuki, Daisei Miyamoto, et al. "HOST RANGE OF INFLUENZA VIRUSES AND APPROACH TO DEVELOP NEW ANTI-INFLUENZA DRUGS." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.443.

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Hassan, Hammed H. A. M., and Raafat Soliman. "DI-ALPHA-N-(2'-AZETIDINONE)-2-AZETIDINONE HAVING N-SULFONAMIDE DRUGS SIDE CHAIN: A NEW TYPE OF BETA-LACTAMS CONTAINING CARBOHYDRATES." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.636.

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Toth, Istvan, Joanne Blanchfield, Ross McGeary, Ben Ross, and Yiu-Ngok Chan. "LIPOSACCHARIDES IN DRUG DELIVERY." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.489.

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Thanh Le, Giang, Chris Clark, Max Broadhurst, et al. "SUGARS AS SCAFFOLDS FOR DRUG DESIGN." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.565.

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Houston, Douglas R., Ian Eggleston, Martin G. Peter, Bjornar Synstad, Vincent G. H. Eijsink, and Daan M. F. van Aalten. "CHITINASES - REACTION MECHANISM AND STRUCTURE-BASED DRUG DESIGN." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.472.

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Ferguson, Michael A. J., John S. Brimacombe, Tunhan Chang, Arthus Crossman, John M. Lucia A. Guther, and Janine R. Roper. "GPI AND GLYCOPROTEIN BIOSYNTHESIS AS TARGETS FOR ANTI-PARASITE DRUG DESIGN." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.363.

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Brennan, Patrick J. "THE CARBOHYDRATES OF MYCOBACTERIUM TUBERCULOSIS AND THEIR ROLES IN THE TB DRUG DISCOVERY PROCESS." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.368.

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Reports on the topic "Carbohydrate drugs"

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Perlin, David S. Evaluation of Carbohydrate-Derived Fulvic Acid (CHD-FA) as a Topical Broad-Spectrum Antimicrobial for Drug-Resistant Wound Infections. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada599044.

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