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Dissertations / Theses on the topic 'Carbohydrates'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Drinnan, Nicholas Barry. "Towards the synthesis of biologically active carbohydrates and carbohydrate mimetics /." [St. Lucia, Qld], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18237.pdf.

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2

Hill, Anthony David. "Computational methods in the study of carbohydrates and carbohydrate-active enzymes." [Ames, Iowa : Iowa State University], 2006.

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3

Scaffidi, Adrian. "Synthetic endeavours in carbohydrates." University of Western Australia. School of Biomedical, Biomolecular and Chemical Sciences, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0114.

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The overwhelming occurrence and structural diversity of carbohydrates in Nature indicate their importance in a range of fundamental life processes. Indeed, it is this diversity that has lead to the two equally diverse groups of carbohydrate-processing enzymes, namely the glycoside hydrolases and glycosyl transferases. Thus, understanding the role of both carbohydrates and their processing enzymes in biological systems has attracted significant attention. This thesis, firstly, describes endeavours towards the synthesis of an inositol ?- amino acid, along with a series of sugar α-substituted car

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4

Smith, Paul W. "Carbohydrates in synthesis." Thesis, University of Oxford, 1986. https://ora.ox.ac.uk/objects/uuid:97dd273b-2577-4556-8889-361f801a826a.

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The use of carbohydrates as starting materials for organic synthesis is illustrated by the synthesis of several polyhydroxylated piperidine, pyrrolidine, indolizine and pyrrolizidine alkaloids. Nucleophilic displacement by azide ion at C-2 in a D-glucose derivative, with subsequent intramolecular cyclisation through nitrogen onto the C-6 or C-5 position and functional group manipulation, led to the synthesis of: 1,5-dideoxy-1,5-imino-D-mannitol; 1,2,5-trideoxy-1,5-imino-D-arabinohexitol; 1,5-dideoxy-1,5-imino-D-glucitol; 2-Acetamido-1,5-imino-1,2,5- trideoxy-D-glucitol; 2-Acetamido-1,5-imino-1

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5

Wilson, Francis X. "Carbohydrates in synthesis." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280014.

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6

Hotchkiss, David J. "Studies on branched carbohydrates." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442450.

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7

Homan, Christopher David. "Phosphorus derivatives of carbohydrates." Thesis, University of Newcastle Upon Tyne, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239564.

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8

Laventine, Dominic. "Hetero-annulation of carbohydrates." Thesis, University of Leicester, 2006. http://hdl.handle.net/2381/29981.

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The aim of the research to be undertaken is the synthesis of hetero-annulated glucose derivatives. In particular the synthesis of five-, six-, and seven- and eight-membered N-containing fused heterocycles is desired, with the nitrogen attached at the C-2 and C-3 position of the sugar ring. Emphasis is placed upon using the sugar ring as a scaffold to enable diastereoelective synthesis. A variety of synthetic techniques are to be employed to achieve ring-closure, especially reductive lamination, ring-closing metathesis and photochemical methods of annulation. (Fig. 9206A).;Such compounds could

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9

Dhamjewar, R. "Synthesis of complex carbohydrates." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1991. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3004.

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10

Reddy, G. V. "Synthesis of complex carbohydrates." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1990. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2975.

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11

Jordaan, Michelle Bernitta. "Effect of processing on the starch and glycemic properties of Digitaria spp." Thesis, Cape Peninsula University of Technology, 2013. http://hdl.handle.net/20.500.11838/2024.

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Thesis (MTech (Food Technology))--Cape Peninsula University of Technology, 2013.<br>Acha starch was isolated and purified from clean and milled acha grain. Functional, thermal and physicochemical properties of acha starch were analysed using appropriate methods. Wheat starch was used as the reference standard. Acha bread from acha grain was baked and the consumer sensory acceptability was evaluated and white wheat bread was used as the reference standard. The effect of baking, boiling, steaming and microwaving on the starch and glycemic properties of the acha starch was evaluated. With

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12

Brigden, C. J. "Surface carbohydrates of Serratia marcescens." Thesis, University of Hull, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375628.

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13

Kaloo, Sara. "Glycosylation of Carbohydrates by Glycosyltranferases." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508556.

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14

Straub, Julie Ann. "The total synthesis of carbohydrates." Thesis, Massachusetts Institute of Technology, 1987. http://hdl.handle.net/1721.1/14622.

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15

Fontenelle, Clement. "The synthesis of polyfluorinated carbohydrates." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/374676/.

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Carbohydrates are essential to many fundamental biological processes throughout Nature. Although generally specific for their cognate protein receptors, typical protein carbohydrate affinities are only in the micromolar to millimolar range. Polyfluorination has emerged as an attractive strategy to enhance this affinity in order to develop carbohydrate based inhibitors and therapeutics. This thesis describes three syntheses of 3,4-dideoxy 3,3,4,4-tetrafluoro-Dmannopyranose and D-glucopyranose. Polyfluorination of carbohydrates has important consequences on the hydrogen bond properties of the ad

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16

Ismail, Dayana Qhairunisa. "Off-template functionalisation of carbohydrates." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/offtemplate-functionalisation-of-carbohydrates(d052ed49-e722-4af4-a8d4-348b153adbd2).html.

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The conjugate addition of organometallic reagents to α,β-unsaturated carbonyl compounds has been studied extensively and is now one of the most important methods for carbon-carbon bond formation. In devising a novel approach to the synthesis of C-glycosides such as gilvocarcin M, we had occasion to investigate the conjugate addition reactions of a diverse range of nucleophilic reagents (i.e. cuprate, RMgX, R-Li, NR2 and ylides) with a number of γ-alkoxy-α,β-unsaturated compounds (esters, ketones, aldehydes, nitro and sulfones): a sequence which hitherto has received scant attention. The stereo

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17

Blixt, Ola. "Enzymatic solid-phase synthesis of carbohydrates /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5704-1.pdf.

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18

Lunn, R. J. "Enantiospecific syntheses of alkaloids from carbohydrates." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376938.

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19

Smith, Kirsten Elisabeth. "Carbohydrates, insulin and the cardiovascular system." Thesis, University of Nottingham, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.546513.

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20

Burroughs, Laurence. "Investigating the prebiotic genesis of carbohydrates." Thesis, University of York, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.546821.

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21

Shan, Yulong. "Bioactive carbohydrates : isolation, synthesis and conjugation." Thesis, Bangor University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.556079.

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In this thesis four projects related to bioactive carbohydrates are described. The first project is about the extraction of iminosugars from Hyacinthoides non-scripta. This is the first time that extraction from English bluebell seeds has been described. Efficient extraction and isolation methods are reported. Another project discusses the development of a total synthetic carbohydrate conjugate vaccine candidate against Streptococcus pneumoniae type 14 using Gold nanoparticles as carrier. The synthetic pathway of the introduction of a linker for conjugation, and the deprotection of the tetrasa

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22

Zhu, Fan, and 朱帆. "Interactions of carbohydrates with phenolic compounds." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45584710.

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23

Daly, Mark Elliot. "The metabolic effects of dietary carbohydrates." Thesis, University of Newcastle Upon Tyne, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341781.

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24

Rullay, Atvinder Kumar. "Investigations of chemoenzymatic synthesis of carbohydrates." Thesis, University of Warwick, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342690.

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25

Tang, Min. "Novel biodegradable polyesters derived from carbohydrates." Thesis, Imperial College London, 2009. http://hdl.handle.net/10044/1/9017.

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This thesis concerns the synthesis of new biodegradable polyesters from carbohydrates.All the new products have been characterised using nuclear magnetic resonance (NMR)spectroscopy and mass spectrometry; some have been studied using X-raycrystallography. In Chapter 1, which is the introduction, some of the leadingbiodegradable polymers are introduced, in particular attention is paid to polyesterswhich are synthesised from carbohydrates. In addition, the standard polymerisationmethods for the polyester synthesis - ring opening polymerisation and steppolymerisation - are described. Chapter 2 de

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26

Licisyn, Thomas A. "Synthesis of cyclopropyl glycosides and glycosyl phenylsulfinate esters applications in carbohydrate chemistry /." Click here for download, 2007. http://proquest.umi.com/pqdweb?did=1276418261&sid=2&Fmt=2&clientId=3260&RQT=309&VName=PQD.

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27

Zhang, Zhiyuan. "Synthesis of the monodeoxy neoglycolipid analogues of globotrioside development of some new methods in carbohydrate chemistry /." Lund : Organic Chemistry 2, Lund Institute of Technology, University of Lund, 1996. http://catalog.hathitrust.org/api/volumes/oclc/39264277.html.

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28

Tonelli, Devin L. "Small Molecule Ice Recrystallization Inhibitors and Their Use in Methane Clathrate Inhibition." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/23994.

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Inhibiting the formation of ice is an essential process commercially, industrially, and medically. Compounds that work to stop the formation of ice have historically possessed drawbacks such as toxicity or prohibitively high active concentrations. One class of molecules, ice recrystallization inhibitors, work to reduce the damage caused by the combination of small ice crystals into larger ones. Recent advances made by the Ben lab have identified small molecule carbohydrate analogues that are highly active in the field of ice recrystallization and have potential in the cryopreservation of li

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29

Lloyd, Pamela G. "Organization of carbohydrate metabolism in vascular smooth muscle." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9974656.

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30

Mendlik, Matthew T. "Syntheses and investigations of 2,6-dideoxysugars contained in diverse bioactive compounds." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1120673161.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from second page of PDF file. Document formatted into pages; contains xix, 347 p.; also includes graphics. Includes bibliographical references (p. 183-192). Available online via OhioLINK's ETD Center

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31

Watt, Matthew J., and mikewood@deakin edu au. "Adrenergic regulation of carbohydrate metabolism during exercise." Deakin University. School of Health Sciences, 2001. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20051202.092251.

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1. This series of studies was undertaken to examine the adrenergic regulation of carbohydrate metabolism during exercise. Recreationally active males were tested during moderate to intense exercise on a stationary cycle ergometer. Venous and arterial plasma obtained from indwelling catheters was analysed for hormonal and metabolite responses, and hepatic glucose production and glucose uptake were measured using the tracer-dilution method with stable isotopes. Muscle samples were obtained by the needle biopsy technique to examine muscle glycogen utilisation and the flux of related muscle metab

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32

Hudgeons, Jeremy L. "The establishment, biological success and host impact of Diorhabda elongata, imported biological control agents of invasive Tamarix in the United States." Thesis, [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-1502.

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33

Säwén, Elin. "NMR spectroscopy and MD simulations of carbohydrates." Doctoral thesis, Stockholms universitet, Institutionen för organisk kemi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-61569.

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Knowledge about the structure, conformation and dynamics of carbohydrates is important in our understanding of the way carbohydrates function in biological systems, for example in intermolecular signaling and recognition. This thesis is a summary of five papers studying these properties in carbohydrate-containing molecules with NMR spectroscopy and molecular dynamics simulations. In paper I, the ring-conformations of the six-membered rings of two carbaiduronic analogs were investigated. These carbasugars could potentially be used as hydrolytically stable mimics of iduronic acid in drugs. The s

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34

DiCesare, John C. "Carbohydrates as chiral auxiliaries in organometallic reactions." Diss., Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/27389.

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35

Stimpson, William Thomas. "The asymmetric synthesis of isotopically labelled carbohydrates." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.488773.

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36

Moore, Sarah G. "The synthesis of phosphonate analogues of carbohydrates." Thesis, University of Manchester, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527569.

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This t~esis is concerned with the synthesis of phosphonate analogues of carbohydrates as stable lsosteres of the corresponding phosphates. Analogues of glucose-6-phosphate (Part A) and mannose-6-phosphate (Part B) were prepared. Part A Glucose-6-phosphatase plays a central role in the homeostatic regulation of blood glucose, by catalysing the conversion of glucose-6-phosphate to glucose in the terminal steps of both gluconeogenesis and glycogenolysis. Abnormally high glucose-6- phosphatase activity has been noted in some cases of diabetes mellitus. Phosphonate analogues of glucose-6-phosphate

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37

Yin, Xiang Sheng. "Physical and enzymic modification of barley carbohydrates." Thesis, Heriot-Watt University, 1986. http://hdl.handle.net/10399/1966.

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38

Aloui, Mahmoud. "Use of carbohydrates in pseudo-sugar synthesis." Thesis, University of Salford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334027.

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39

Patel, Mitul Kiran. "Unravelling the biological roles of charged carbohydrates." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:6fb4de15-5585-4f62-ae56-4c6bf32593ab.

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The phosphate and sulfate esters of carbohydrates are widespread in nature, where they partake in a variety of signalling roles. This thesis focuses on the involvement of trehalose-6-phosphate (Tre-6-P) in regulating plant growth, and the function of sulfated carbohydrates in the immune response. In plants, Tre-6-P is a critical messenger that conveys environmental information for the control of metabolic state. Beneficial natural conditions lead to an increase in the in vivo concentration of Tre-6-P, which in turn triggers biosynthetic processes facilitating plant growth. However, the mechani

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40

Lewallen, Daniel M. "Development of synthetic carbohydrates for capturing toxins." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1288969515.

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41

GoncÌ§alves, Pedro Miguel Lopes. "Modification of carbohydrates using enzymes as catalysts." Thesis, University of Liverpool, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288199.

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42

Poland, Lynette C. "The effect of a carbohydrate supplement on multiple bout resistance performance training during energy restriction in male resistance trainers." Thesis, This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-06162009-063322/.

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43

Dhake, Parag. "Reexamination of Reverse Anomeric Effect (RAE)." Fogler Library, University of Maine, 2008. http://www.library.umaine.edu/theses/pdf/DhakeP2008.pdf.

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44

Ladomenou, Kalliopi. "Podand-type receptors for sugar recognition." Thesis, University of Liverpool, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250367.

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45

Manning, Charles Edward. "Formation and melting of gellan polysaccharide gels." Thesis, Cranfield University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282399.

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46

Houtkooper, Linda, and Jaclyn Maurer. "Carbohydrate Needs." College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 2006. http://hdl.handle.net/10150/146628.

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47

Sundin, Birgitta. "Dental caries and sugar-containing products analytical studies in teenagers /." Malmö [Sweden] : Dept. of Pedodontics, Faculty of Odontology, Lund University, 1994. http://catalog.hathitrust.org/api/volumes/oclc/32290695.html.

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48

Lim, Tang Kuan. "NMR studies of carbohydrates in the solid state." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/27129.

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The work described herein entails the application of solid-state n.m.r. methods to both mono- and polysaccharide carbohydrates. Two major n.m.r. methods have been evaluated for studying these substances, namely, the carbon-13 cross-polarization-magic angle spinning method and the deuterium quadrupole echo method. Heptakis-(2,6-di-O-methyl)- β-cyclodextrin and β-cyclodextrin peracetate were prepared and, together with α-and β-cyclodextrins as hosts, were used to encage a variety of organic guest molecules. A number of metal sugar conjugates were prepared according to the procedures documented

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49

Vanmaele, Rosa Pauline. "Role of carbohydrates in enteropathogenic Escherichia coli adherence." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0003/NQ39602.pdf.

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50

Eklund, Robert. "Computational Analysis of Carbohydrates : Dynamical Properties and Interactions." Doctoral thesis, Stockholm : Department of Organic Chemistry, Stockholm University, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-538.

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