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Journal articles on the topic 'Carbomer gel'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Bezugla, Olena, Anna Liapunova, Igor Zinchenko, Oleksii Liapunov, Nikolay Lyapunov, and Yurij Stolper. "Study of factors affecting the in vitro release of ketoprofen from carbomers-based gels." ScienceRise: Pharmaceutical Science, no. 6(40) (December 30, 2022): 4–20. http://dx.doi.org/10.15587/2519-4852.2022.268933.

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The aim. To identify some factors affecting the in vitro release of ketoprofen from carbomer-based gels. Materials and methods. Carbomer-based gels containing ketoprofen as well as a Newtonian liquid without carbomer, which was the dispersion medium of the gel, were studied by rotational viscometry and spin probe method. The flow behaviour and rheological parameters were determined using the rheograms, and the rotational correlation times of the two dissolved spin probes, the molecules of which contain a carboxyl group or an amino group, were determined by EPR spectra. In vitro release t

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Olena, Bezugla, Liapunova Anna, Zinchenko Igor, Liapunov Oleksii, Lyapunov Nikolay, and Stolper Yurij. "Study of factors affecting the in vitro release of ketoprofen from carbomers-based gels." ScienceRise: Pharmaceutical Science, no. 6(40) (December 30, 2022): 4–20. https://doi.org/10.15587/2519-4852.2022.268933.

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<strong>The aim</strong><strong>.</strong> To identify some factors affecting the in vitro release of ketoprofen from carbomer-based gels. <strong>Materials and methods.</strong> Carbomer-based gels containing ketoprofen as well as a Newtonian liquid without carbomer, which was the dispersion medium of the gel, were studied by rotational viscometry and spin probe method. The flow behaviour and rheological parameters were determined using the rheograms, and the rotational correlation times of the two dissolved spin probes, the molecules of which contain a carboxyl group or an amino gr

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Ruban, O. A., and Yu. S. Maslii. "RESEARCH ON THE CHOICE OF RATIONAL CONCENTRATION OF THE GEL FORMING AGENT IN THE COMPOSITION OF DENTAL GEL." Annals of Mechnikov Institute, no. 2 (July 1, 2019): 29–33. https://doi.org/10.5281/zenodo.3265076.

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Taking into account the wide spreading and etiopathogenetic features of the course of inflammatory diseases of periodontium and oral mucosa, it is rational to use semisolid drugs of local action, namely, dental gels. The main issue when developing this dosage form is the choice of the gel former and its concentration. Based on previous studies as the gel basis for the development of a new dental gel with «Phytodent» tincture, choline salicylate 80%, and lidocaine hydrochloride the Carbomer Polacril® 40P, which is authorized for use in dentistry and has the ability to form trans

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Saphira, Ersih, and Marini Marini. "FORMULASI SEDIAAN MASKER GEL PEEL-OFF DARI EKSTRAK DAUN SIRIH (Piper Betle L.) DENGAN MENGGUNAKAN VARIASI GELLING AGENT CARBOMER 940." HERBAPHARMA : Journal of Herb Farmacological 4, no. 1 (2022): 11–18. http://dx.doi.org/10.55093/herbapharma.v4i1.202.

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ABSTRAK Daun sirih (Piper betle L.) memiliki kandungan senyawa kimia berupa saponin, flavonoid, polifenol, dan minyak atsiri. Dalam kandungan senyawa daun sirih (Piper betle L.) senyawa yang dapat memberikan aktivitas menghambat pertumbuhan bakteri staphylococcus aureus adalah flavonoid. Tujuan penelitian ini adalah untuk membuat formulasi sediaan masker gel peel-off dengan ekstrak daun sirih sebagai anti jerawat dengan menggunakan basis carbomer 940 sebagai basis untuk memperoleh sediaan masker gel peel-off yang baik dan mengetahui uji evaluasi masker gel peel-off dengan konsentrasi bas

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Sutiswa, Shandra Isasi. "Uji Efektivitas Hand Sanitizer Spray Gel dengan Carbomer 940 sebagai Produk Preventif pada Kondisi Darurat." Indonesian Journal of Pharmaceutical Science and Technology 12, no. 2 (2025): 178–83. https://doi.org/10.24198/ijpst.v12i2.45186.

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Hand sanitizer dikenal karena kemampuannya membunuh kuman dengan cepat karena kandungan alkoholnya, sehingga lebih efektif daripada mencuci tangan dengan sabun dan air. Namun, penggunaan hand sanitizer berbahan dasar alkohol secara berlebihan dapat menyebabkan iritasi dan kekeringan pada kulit. Alkohol bersifat polar dan mudah menguap, yang menyebabkan kulit cepat kering dan mengurangi efektivitasnya. Untuk mengatasi hal ini, agen pembentuk gel seperti Carbomer 940 ditambahkan ke dalam formulasi gel semprot. Carbomer 940 menawarkan stabilitas tinggi dan toksisitas rendah, sehingga meningkatkan

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Achsia, Aria Agustina, Ary Kristijono, and Dara Pranidya Tilarso. "Aktivitas Anti Candida albicans ATCC 14053 Sediaan Pasta Gigi Gel Ekstrak Daun Jengkol (Archidendron pauciflorum) dengan Kombinasi Na-CMC dan Karbomer." Jurnal Sains dan Kesehatan 3, no. 2 (2021): 177–87. http://dx.doi.org/10.25026/jsk.v3i2.267.

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Jengkol leaf extract can inhibit the growth of the fungus Candida albicans because it contains flavonoids, saponins, and tannins. Candida albicans species are most commonly found in the oral cavity that can cause various diseases in humans as canker sores and skin lesions. The purpose of this study was to formulate jengkol leaf extract into gel toothpaste preparations by distinguishing variations in the concentration of carbomer as a gelling agent. The research method used is experimental. Jengkol leaf samples extracted using the maceration method with 70% ethanol. The concentration of active

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Sulayman, Halah T. "Some Variable Affecting Formulationof Tinidazole Mucoadhesive Oral Gel." Al Mustansiriyah Journal of Pharmaceutical Sciences 10, no. 2 (2011): 165–78. http://dx.doi.org/10.32947/ajps.v10i2.307.

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Tinidazole (TZ) is an antibacterial drug used for treatment of periodentitis.More benefit may be obtained by the application of a localized oral drug delivery system consist of mucoadhesive polymers which increase the contact time between the base and the oral tissue. Different gel formulations were prepared using the bioadhesive polymers carbomer 941, sodium caroxymethylcellulose (SCMC), and guar gum. The influence of polymer type and polymers blend in varying ratio on the viscosity, bioadhesive strength, swelling index and drug release were evaluated. SCMC based gel showed fastest release in

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Hiba, Salmo M. "Investigation the effect of different concentrations of carbomer & Co solvent propylene glycol on the releasing process of tinidazole from vaginal aqueous gel." Al Mustansiriyah Journal of Pharmaceutical Sciences 3, no. 1 (2006): 75–85. http://dx.doi.org/10.32947/ajps.v3i1.411.

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The ability of local mucoadhesive vaginal aqueous gel to deliver the antibacterial, antiprotozoal tinidazole (TND) to vaginal endolayers is dependent on its releasing out of the drug from vehicle to the mucosal layer of the vagina and then exert its local effect. This depends upon the physicochemical properties of the drug, vehicle & the composition of the releasing medium used.The effect of different concentration of carbomer 941(0.5, 1&2% w/w) on the release of TND (2%w/w) from the aqueous gel base in absence & presence of various concentration of propylene glycol (PG) to the sti

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Mardiana, Lia, Titik Sunarni, and Mimiek Murukmihadi. "Optimasi Kombinasi Carbomer dan CMC-Na dalam Sediaan Gel Pewarna Rambut Ekstrak Bunga Telang (Clitoria ternatea L.)." PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) 17, no. 1 (2020): 128. http://dx.doi.org/10.30595/pharmacy.v17i1.6261.

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Ekstrak bunga telang (Clitoria ternatea L.) dapat digunakan sebagai pewarna alami karena mengandung pigmen antosianin. Penelitian ini bertujuan untuk mengetahui pengaruh dari kombinasi carbomer dan CMC-Na terhadap stabilitas sifat fisik dan pewarnaan gel serta iritasi formula optimum yang diperoleh. Serbuk kering bunga telang dimaserasi menggunakan gelombang ultrasonik dengan air yang diasamkan dengan asam tartrat sebagai pelarut. Ekstrak yang diperoleh dari penyaringan vakum kemudian dikeringkan dengan metode freeze dry selama 3 hari. Formula optimum yang diperoleh diuji iritasi, stabilitas m

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Chaerunisaa, Anis Yohana, Patihul Husni, and Fairuzati Anisah Murthadiah. "Modifikasi Viskositas Kappa Karagenan Sebagai Gelling Agent Menggunakan Metode Polymer Blend." Journal of The Indonesian Society of Integrated Chemistry 12, no. 2 (2020): 73–83. http://dx.doi.org/10.22437/jisic.v12i2.12040.

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[ Viscosity Modification of Kappa Carrageenan as Gelling Agent Using Polymer Blend Method ] Gelling agent merupakan zat hidrokoloid yang dapat meningkatkan viskositas dan menstabilkan sediaan gel. Karagenan sebagai salah satu gelling agent memiliki konsistensi yang kaku dan padat. Untuk mendapatkan gel karagenan dengan viskositas yang memenuhi standar suatu gelling agent, tetapi memiliki sifat fisikokimia dan stabilitas yang memenuhi syarat, maka diperlukan modifikasi pada kappa karagenan. Salah satu metode modifikasi gelling agent adalah metode polymer blend. Modifikasi viskositas dari gel ka

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Yusuf, A. L., and D. Nugraha. "Synerisis and Cycling Test the Sendok Leaf Extract Gel (Plantago Mayor L.) with Optimization of Variations of Gelling Agent Carbomer 940 Concentration." International Journal of Innovative Research in Medical Science 6, no. 12 (2021): 908–10. http://dx.doi.org/10.23958/ijirms/vol06-i12/1294.

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The purpose of this study was to determine the effect of the concentration of the gelling agent Carbomer 940 on the gel of daun Leaf Extract (Plantago major L.). The method used is the experimental method. The extraction method used is maceration with 96% alcohol. The design in this study is the manufacture of a gel formulation of sendok Leaf extract (Plantago major L.) with the concentration of the gelling agent Carbomer 940 and the syneresis test. Syneresis test results show that all formulas do not occur syneresis. The results of the cycling test showed that the sendok Leaf (Plantago major

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Andrade, Ana Ochoa, María Emma Parente, and Gastón Ares. "Screening of mucoadhesive vaginal gel formulations." Brazilian Journal of Pharmaceutical Sciences 50, no. 4 (2014): 931–41. http://dx.doi.org/10.1590/s1984-82502014000400029.

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Rational design of vaginal drug delivery formulations requires special attention to vehicle properties that optimize vaginal coating and retention. The aim of the present work was to perform a screening of mucoadhesive vaginal gels formulated with carbomer or carrageenan in binary combination with a second polymer (carbomer, guar or xanthan gum). The gels were characterised using in vitroadhesion, spreadability and leakage potential studies, as well as rheological measurements (stress and frequency sweep tests) and the effect of dilution with simulated vaginal fluid (SVF) on spreadability. Res

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Mardiana, Lia, Titik Sunarni, and Mimiek Murukmihadi. "OPTIMASI KOMBINASI CARBOMER DAN CMC Na DALAM SEDIAAN GEL PEWARNA RAMBUT EKSTRAK BUNGA TELANG (Clitoria ternatea L.)." Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) 2, no. 2 (2019): 80. http://dx.doi.org/10.35799/pmj.2.2.2019.26531.

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ABSTRACTColor and perfume substance factors are essential in a hair dye preparation. Anthocyanin in Butterfly Pea flower (Clitoria ternatea L.) has the potency to act as a natural dye. The physical attributes of hair dye are determined from the combination of carbomer gel and CMC Na as the gelling agent. This research aimed to discover the effect of the combination of carbomer and CMC Na on the physical attributes of the hair dye and to know the optimal formula composition as well as its physical stability during storage and in irritation test. Dry powder of the Butterfly Pea flower was macera

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Sudjono, Tanti Azizah. "PENGARUH KONSENTRASI GELLING AGENT CARBOMER 934 DAN HPMC PADA FORMULASI GEL LENDIR BEKICOT (Achatina fulica) TERHADAP KECEPATAN PENYEMBUHAN LUKA BAKAR PADA PUNGGUNG KELINCI." Pharmacon: Jurnal Farmasi Indonesia 13, no. 1 (2015): 6–11. http://dx.doi.org/10.23917/pharmacon.v13i1.20.

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Lendir bekicot mengandung glycosaminoglycan yang dapat menyembuhkan luka bakar. Sediaan ini dapat dibuat dalam bentuk gel. Perbedaan viskositas gel dapat dipengaruhi oleh gelling agent. Penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi carbomer 934 dan HPMC pada formulasi gel lendir bekicot terhadap viskositas dan kecepatan penyembuhan luka bakar. Penelitian ini menggunakan rancangan penelitian sama subyek menggunakan 12 ekor kelinci jantan New Zealand yang dicukur bulu punggungnya dan dibagi menjadi 6 area perlakuan, yaitu menggunakan kontrol positif (Bioplasenton), kontrol negat

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Suryani, Suryani, Andi Nafisah, and Syahrir Mana'an. "Optimasi Formula Gel Antioksidan Ekstrak Etanol Buah Bligo (Benincasa hispida) dengan Metode Simplex Lattice Design (SLD)." Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) 3, no. 2 (2017): 150–56. http://dx.doi.org/10.22487/j24428744.0.v0.i0.8815.

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Benincasa hispida has many benefits including as antioxidant. This study aims to evaluate the effect of Carbomer 940, HPMC and NaOH concentrations in antioxidant gel formula and to determine Carbomer 940, HPMC and NaOH concentrations that could produce the optimal antioxidant gel formula. Benincasa hispida was extracted by maceration method and antioxidant activity was tested by DPPH method. The antioxidant gels were formulated with variety combinations of Carbomer 940, HPMC and NaOH. The optimal gel formula was obtained by Design Expert 7.1.5 with Simplex Lattice Design method. The physical c

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Abramov, V. A., A. R. Gataullin, S. A. Bogdanova, S. V. Demidov, R. A. Kemalov, and S. R. Allayarov. "Rheological Properties of Gel Systems Based on Gamma-Irradiated Lightly Crosslinked Polyacrylic Acid." Химия высоких энергий 57, no. 6 (2023): 460–64. http://dx.doi.org/10.31857/s0023119323060013.

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The effect of γ-irradiation of the gelling agent Carbomer 141 G, which is lightly crosslinked polyacrylic acid, on the rheological properties of gels based on the carbomer has been studied. It has been found that an increase in the dose of γ-irradiation in air has a destructive effect on the polymer, leading to a decrease in rheological parameters, such as viscosity, yield strength, and hysteresis area. Irradiation of the carbomer in air with doses greater than 300 kGy leads to a significant decrease or the complete loss of its gel-forming properties. At the same time, irradiation of the carbo

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Nugraha, Zen Achmad Redho, Setia Budi, and Yusri Yusri. "Formulasi Dan Evaluasi Fisik Sediaan Deodoran Gel Kombinasi Ekstrak Kulit Jeruk, Teh Hijau Dan Buah Pepaya." Journal Pharmaceutical Care and Sciences 4, no. 1 (2023): 42–54. http://dx.doi.org/10.33859/jpcs.v4i1.402.

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Ekstrak kulit jeruk memiliki aktivitas antibakteri, ekstrak the hijau memiliki aktivitas antiperspirant dan ekstrak papaya memiliki aktivitas sebagai pencerah pada kulit sehingga dikombinasikanlah ketiga ekstrak tersebut dan dibuat sediaan deodoran gel, deodoran gel diharapkan dapat memberikan rasa dingin serta cepat dalam pengaplikasiannya. Dasar konsentrasi carbomer yang digunakan pada penelitian ini yaitu 0,5%-2%. Tujuan penelitian ini yaitu Mendapatkan formulasi deodoran dengan zat aktif tumbuhan serta mendapatkan optimalisasi formulasi dan melihat evaluasi fisik pada sediaan deodoran gel

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Zhang, Yun, Sijia Li, Yanfang Huang, Congjing Song, Weiqiang Chen, and Yiling Yang. "Therapeutic Effect of Liquiritin Carbomer Gel on Topical Glucocorticoid-Induced Skin Inflammation in Mice." Pharmaceutics 16, no. 8 (2024): 1001. http://dx.doi.org/10.3390/pharmaceutics16081001.

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Glucocorticoids are often used and highly effective anti-inflammatory medications, but prolonged topical application may alter the epidermis’ normal structure and function, potentially resulting in a number of adverse effects. Topical glucocorticoid-induced skin inflammation is a dangerous condition that develops after topical glucocorticoid use. The patients become dependent on the medication and, even after the medication is stopped, the dermatitis symptoms recur, severely impairing their quality of life. Thus, the need to aggressively confront Topical glucocorticoid-induced skin inflammatio

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Putri, Melysa, Hafnimardiyanti Hafnimardiyanti, and Dian Savitri. "Efek Variasi Penambahan Carbomer Terhadap Nilai pH, Viskositas dan Aktivitas Mikroba pada Sediaan Hand Sanitizer." REACTOR: Journal of Research on Chemistry and Engineering 2, no. 2 (2021): 32. http://dx.doi.org/10.52759/reactor.v2i2.36.

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Hand sanitizer is an antiseptic in gel form. The gel texture in hand sanitizers is caused by the carbomer which acts as a gelling agent. Therefore, this research was done to observe the effect of carbomer on the value of pH, viscosity, and microbial activity in hand sanitizers. As for testing pH using pH meters, testing viscosity was carried out using the viscometer method, while microbial activity was carried out using the Total Plate Number, Yeast Mold Number and microbial pathogen tests. Based on the data obtained, the carbomer greatly influences the increase in the viscosity of the hand sa

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Agung Aris Diartama, Anak, Suryono Suryono, Sugiyanto Sugiyanto, Putu Irma Wulandari, I. Putu Eka Juliantara, and Kadek Yuda Astina. "Carrageenan Biopolymer for Medical Ultrasonography using Phantom CIRS." E3S Web of Conferences 202 (2020): 12001. http://dx.doi.org/10.1051/e3sconf/202020212001.

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The use of polymer as conductor in medical ultrasonography is very crucial to establish patient diagnosis and to prevent administration of improper treatment. Rapid development in science and technology encourages people to create more innovations that are readily usable. However, these innovations sometimes put health and environmental aspects aside that in turn become disadvantageous to health and may lead to environmental pollution. This research proposes the use of carrageenan biopolymer as a safe alternative for people’s health and the environment. It aims to prove differences in resultin

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Lee, Jong Hoon, Ja Young Moon, Hyeon-Jeong Yoon, and Kyung Chul Yoon. "Effects of Carbomer Eye Gels on the Ocular Surface in Dry Eye Patients." Journal of the Korean Ophthalmological Society 65, no. 1 (2024): 9–15. http://dx.doi.org/10.3341/jkos.2024.65.1.9.

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Purpose: We investigated the clinical effects of Siccafluid carbomer eye gel on the symptoms, tear film, and ocular surface in dry eye patients.Methods: Fifty-five patients with dry eye syndrome were also treated with carbomer eye gel for 6 months. The Dry Eye Questionnaire (DEQ-5), tear film breakup time (TBUT), Schirmer’s test, and ocular surface staining score were assessed during follow-up. Patients were classified into Sjögren’s syndrome and non-Sjögren’s syndrome groups and the effects of the carbomer eye drops in each group were analyzed.Results: Overall, the dry eye patients showed sig

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Maslii, Yuliia, Olena Ruban, Giedre Kasparaviciene, et al. "The Influence of pH Values on the Rheological, Textural and Release Properties of Carbomer Polacril® 40P-Based Dental Gel Formulation with Plant-Derived and Synthetic Active Components." Molecules 25, no. 21 (2020): 5018. http://dx.doi.org/10.3390/molecules25215018.

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The physicochemical properties, especially pH value of dental medicines, have significant influence on the health of oral cavity tissues. The pH of formulations should correspond to the value of saliva pH (5.5–8.0). For carbomer-based gels, the required pH value is obtained by neutralizing them with alkaline components, which leads to their structuring (thickening). This affects the physical properties of the gel, its residence time at the application site and the rate of release of active pharmaceutical ingredient. Therefore, the main purpose of this study is to evaluate the rheological, text

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A, Rukhmakova Olga, Karpenko Irina A, and Yarnykh Tatyana G. "THERMOGRAVIMETRIC STUDIES OF NASAL GEL WITH DRY EXTRACT OF LICORICE ROOT AND ESSENTIAL OILS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 8 (2018): 85. http://dx.doi.org/10.22159/ajpcr.2018.v11i8.24948.

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Objectives: The objectives of this study were to conduct thermogravimetric (TG) studies of nasal gel with dry extract of licorice root and essential oils for the treatment of viral rhinitis.Methods: TG analysis performs on the derivative Q-1000 of the system F. Paulik, I. Paulik, and L. Efdei with platinum-based thermocouple. Then the curves T (temperature changes), TG (changes in weight), DTA (differentiated curve of thermal effects), DTG (differentiated weight change curve) were recorded. As an inert material, the standard is usually aluminum oxide, which should not undergo transformations w

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Zhang, Yang, Jing Li Zhao, and Hong Li Zhou. "Study on the Preparation Process of Salicylic Acid Liposome Gel." Advanced Materials Research 554-556 (July 2012): 828–31. http://dx.doi.org/10.4028/www.scientific.net/amr.554-556.828.

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Objective To optimize the preparation technology of salicylic acid liposome gel. Method Salicylic acid liposome was prepared with reverse evaporating method, and liposome gel was prepared using carbomer-940 as matrix. The encapsulation efficiency and leaking percentage of salicylic acid liposome was determined with centrifugal method, and the preparation technology of liposome gel was optimized with orthogonal test. Results The encapsulation efficiency of salicylic acid liposome was 75.86％, leaking percentage was 1.37％. The optimal preparation technology of liposome gel were carbomer 3g, glyce

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Pratama, Nofran putra, Endah Kurniawati, Tira Risa Oktapiya, Zerli Rahmawati, and Septi Wulandari. "Formulasi Dan Optimasi Sediaan Gel Ekstrak Etanol Kol Ungu (Brassica oleracea L. Var. Capitata F. Rubra) dengan Basis Carbomer." BENCOOLEN JOURNAL OF PHARMACY 4, no. 1 (2024): 1–10. http://dx.doi.org/10.33369/bjp.v4i1.33999.

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Purple cabbage (Brassica oleracea L. Var. Capitata F. Rubra) is known to have anti-inflammatory activity, so it can be used as a medicine to treat inflammation, especially in breastfeeding mothers. To make it easier to use, it is made into a gel formulation. One of the compounds in purple cabbage is anthocyanin which is in the form of glycosides bound to sugar molecules (cyanidin-3 diglucoside-5-glucoside). These compounds have important effects on the body, one of which is anti-inflammatory. To make it easier to use, it is made into a gel formulation. One of the bases used in the formulation

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He, X., L. Jiang, J. Hu та H. Yang. "P0080 Thalidomide-Carbomer Gel for Rectal Administration Alleviates DSS-Induced Colitis and fibrosis in Mouse by Targeting S1pr5 and Il1f9 (Il36γ)". Journal of Crohn's and Colitis 19, Supplement_1 (2025): i444. https://doi.org/10.1093/ecco-jcc/jjae190.0254.

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Abstract Background Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the digestive tract, including ulcerative colitis (UC) and Crohn's disease (CD). Thalidomide, an inhibitor of Tnf-α, is used in IBD treatment but is limited by systemic side effects when taken orally. This study aimed to develop a thalidomide-carbomer gel for rectal administration to reduce systemic side effects and explore new therapeutic targets. Methods An acute colitis model was established using DSS-induced wild-type C57 mice. Mice were treated with thalidomide-carbomer gel via rectal administratio

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Nawwal, Nawwal, Aris Fadillah, and Muhammad Fauzi. "VARIASI KONSENTRASI CARBOMER 940-TRIETHANOLAMINE (TEA) DAN EVALUASI PADA FORMULASI PEELING GEL EKSTRAK KULIT BUAH NANAS (ANANAS COMOSUS)." Jurnal Kesehatan Tambusai 6, no. 1 (2025): 2533–42. https://doi.org/10.31004/jkt.v6i1.40124.

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Kosmetik merupakan sediaan yang digunakan untuk meningkatkan estetika dan kesehatan kulit. Salah satu produk kosmetik yang populer adalah peeling gel, yang berfungsi untuk mengangkat sel kulit mati dan merangsang regenerasi kulit agar tampak lebih halus dan sehat. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi carbomer 940 dan triethanolamine (TEA) terhadap karakteristik fisik serta stabilitas sediaan peeling gel berbasis ekstrak kulit nanas (Ananas comosus). Metode penelitian ini melibatkan formulasi peeling gel dengan tiga variasi konsentrasi carbomer 940 dan TEA, yai

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Chaabani, Lotfi, Merieme Kalou, Ahmed Jakhlouti, and Wiem Aloui. "Efficacy and Tolerability of Anti-inflammatory Drugs in the Treatment of Dry Eye Syndrome." Ophthalmology Research: An International Journal 20, no. 4 (2025): 84–90. https://doi.org/10.9734/or/2025/v20i4469.

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Background: Dry eye syndrome (DES) can affect visual function and general quality of life. It is accompanied by increased osmolarity and inflammation on the ocular surface, leading to insufficient tear secretion and excessive evaporation. Aims: The study aims to evaluate the efficacy and tolerability of anti-inflammatory drugs in the treatment of dry eye syndrome. Study Design: This is a retrospective and comparative study. Place and Duration of Study: Ophthalmology Department of Kasserine between January 2024 and December 2024. Methodology: We included 100 patients with DES. The patients were

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Agustin, Vina, Nur Ismiyati, and Rini Sulistyawati. "Formulasi Sediaan Gel Totol Jerawat Ekstrak Bunga Melati (Jasminum sambac L)." Indonesian Journal on Medical Science 10, no. 1 (2023): 31–36. http://dx.doi.org/10.55181/ijms.v10i1.413.

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Bunga melati memiliki kandungan eugenol, linalool, metil salisilat, benzil alkohol dan indol. Ekstrak bunga melati konsentrasi 30% mampu mencegah pertumbuhan bakteri Propionibacterium acne penyebab jerawat dengan diameter zona hambat 5,58 mm. Penelitian ini bertujuan untuk mengetahui formulasi gel totol jerawat ekstrak bunga melati (Jaminum sambac L) dan evaluasi sifat fisik. Ekstrak etanol bunga melati diperoleh dengan metode maserasi menggunakan pelarut etanol 96%. Formulasi gel dibuat dengan ekstrak etanol bunga melati konsentrasi 30% dan 35%, basis carbomer 940, trietanolamin (TEA), metilp

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Ermawati, Dian, Uswatun Chasanah, Herika Juli Andani, and Khalda Nisrina. "Gel formulations containing Sumbawa's horse milk with carbomer gel base." Farmasains : Jurnal Farmasi dan Ilmu Kesehatan 4, no. 1 (2019): 37. http://dx.doi.org/10.22219/farmasains.v4i1.6892.

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Peptides from Sumbawa horse milk are active as antibacterial and antioxidant. Horse milk has a higher content of vitamin C than cow or goat's milk, and cream products that contain milk can overcome dry skin. The Gel is one of the topical dosage forms suitable for acne medications and oily skin types. This study aimed to determine the effect of variations in horse milk content formulated in gel preparations with carbomer 1% base as gelling agents on physical characteristics (organoleptic, viscosity, pH) and antibacterial activity in Propionibacterium acnes. In this study, gel preparations were

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Vásconez-Maza, Marco D., Pedro Martínez-Pagán, Hasan Aktarakçi, María C. García-Nieto, and Marcos A. Martínez-Segura. "Enhancing Electrical Contact with a Commercial Polymer for Electrical Resistivity Tomography on Archaeological Sites: A Case Study." Materials 13, no. 21 (2020): 5012. http://dx.doi.org/10.3390/ma13215012.

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This communication reports an improvement of the quality of the electrical data obtained from the application of electrical resistivity tomography method on archaeological studies. The electrical contact between ground and electrode enhances significantly by using carbomer-based gel during the electrical resistivity tomography measurements. Not only does the gel promote the conservation of the building surface under investigation, but it also virtually eliminates the necessity of conventional spike electrodes, which in many archaeological studies are inadequate or not permitted. Results eviden

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Tsabitah, Amira Fawwaz, Abdul Karim Zulkarnain, Mae Sri Hartanti Wahyuningsih, and Dwi Aris Agung Nugrahaningsih. "Optimasi Carbomer, Propilen Glikol, dan Trietanolamin Dalam Formulasi Sediaan Gel Ekstrak Etanol Daun Kembang Bulan (Tithonia diversifolia)." Majalah Farmaseutik 16, no. 2 (2020): 111. http://dx.doi.org/10.22146/farmaseutik.v16i2.45666.

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Ekstrak etanol daun kembang bulan atau Tithonia diversifolia telah diteliti memiliki kemampuan sebagai anti keloid yang baik. Tujuan penelitian ini adalah untuk mendapatkan formula gel dengan sifat fisik dan stabilitas yang baik. Metode yang digunakan dalam optimasi ini adalah Simplex Lattice Design. Formula optimum gel dibuat dari bahan carbomer, propilen glikol, dan trietanolamin. Parameter yang diukur adalah viskositas, pH, daya sebar, freeze and thaw cycles, dan sineresis. Hasil uji kemudian dianalisis menggunakan paired t-test.Hasil penelitian menunjukan bahwa formula optimum gel terdiri

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Putra, I. Gusti Ngurah Agung Windra Wartana, I. Putu Gede Adi Purwa Hita, I. Gusti Ayu Agung Septiari, and Ida Ayu Manik Partha Sutema. "PENGARUH VARIASI CARBOMER DAN GLISERIN TERHADAP KUALITAS HAND SANITIZER EKSTRAK ALOE VERA." Medical Sains : Jurnal Ilmiah Kefarmasian 6, no. 2 (2021): 133–40. http://dx.doi.org/10.37874/ms.v6i2.310.

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Kondisi pandemi COVID-19 membuat penggunaan hand sanitizer dimasyarakat menjadi meningkat. Kepraktisan merupakan salah satu alasan masyarakat lebih mengunakan sediaan antiseptik hand sanitizer dibanding membersihkan tangan dengan sabun dan air mengalir. Tingginya penggunaan hand sanitizer membuat perlu adanya inovasi produk sehingga dapat memberikan kepuasan masyarakat yang lebih maksimal. Inovasi yang sering dilakukan oleh formulator adalah inovasi formula yang terkait pembaharuan bahan bahan dalam sediaan untuk meningkatkan kualitas dari suatu produk. Dalam melakukan inovasi, perlu melewati

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Martinović, Milica, Nenad Stojanović, and Ivana Nešić. "Textural and sensory characterization of carbomeric gels with panthenol." Acta Facultatis Medicae Naissensis 39, no. 2 (2022): 232–43. http://dx.doi.org/10.5937/afmnai39-31063.

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Introduction. The aim of this study was to evaluate the influence of the carbomer concentration (used as the gelling agent, in the range 0.5 - 2.0%) on textural and sensory characteristics of gels with 3% panthenol using sensory analysis as subjective and texture analysis as an objective assessment method. An active substance in the gels was panthenol, which also acted as a neutralizing agent of the carbomer. Participants and methods. Twenty female panelists, aged between 20 and 36, participated in the sensory study and had to fulfill a questionnaire regarding product attributes before, during

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Santoso, Joko, and Heru Nurcahyo. "OPTIMASI GEL HAND SANITIZER OLEUM CITRI DENGAN KOMBINASI CARBOPOL, LIDAH BUAYA DAN TEA MENGGUNAKAN SIMPLEX LATTICE DESIGN." Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 6, no. 1 (2021): 21–28. http://dx.doi.org/10.36387/jiis.v6i1.569.

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Handsanitizer gel is composed of various additives such as geling agents, humectants and neutralizing / stabilizing agents. This material is certainly a basic ingredient that will affect the shape and quality of the preparation. Carbopol is very good when used, so that low levels can provide a significant viscosity response. Eleven hand sanitizer gel formulas with variations of carbomer, aloe vera and TEA were tested for their physical properties including organoleptic, homogeneity test, pH test, spreadability and adhesion test . The optimum formula is obtained by using the Simplex Lattice Des

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Syafitri, Anggun, Masria Phetheresia Sianipar, and Ardhana Fantika. "FORMULASI DAN UJI EFEKTIVITAS SEDIAAN EKSTRAK ETANOL KULIT PEPAYA (Carica papaya L) SEBAGAI BRIGHTENING GEL SERUM." Jurnal Penelitian Farmasi & Herbal 7, no. 1 (2024): 42–51. https://doi.org/10.36656/jpfh.v7i1.1998.

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Facial skin problems that often occur in women and adolescents are dull skin and dark looking skin. Papaya peel (carica papaya L) contains flavonoid compounds which function as antioxidants to brighten the skin. This study aims to formulate papaya peel extract into a serum gel dosage form and observe its effectiveness on the skin of volunteers for 4 weeks of treatment. The research was started by making papaya peel extract which was obtained by maceration method. Then the extract was formulated into serum gel preparations with varying concentrations of gelling agent Carbomer 940 4%, 5%, 6%. Th

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&NA;. "Carbomer polymer gel: a future in contraception?" Inpharma Weekly &NA;, no. 1606 (2007): 8. http://dx.doi.org/10.2165/00128413-200716060-00023.

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Jumariati, Siti, Risky Juliansyah Putri, Juliana Baco, and Nur Hatidjah Awaliyah Halid. "Pengaruh Variasi Basis Gel Terhadap Karakteristik Fisik Sediaan Masker Gel Peel Off dari Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa bilimbi L.)." Jurnal Pharmacia Mandala Waluya 4, no. 1 (2025): 70–81. https://doi.org/10.54883/jpmw.v4i1.330.

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Penyebab timbulnya jerawat adalah produksi kelenjar minyak berlebih yang menyebabkan pori-pori penuh sehingga menimbulkan terjadinya tempat tumbuh bakteri Propionibacterium acnes. Zat aktif yang dapat menghambat pertumbuhan bakteri tersebut adalah daun belimbing wuluh (Averrhoa bilimbi L.) karena mengandung senyawa flavanoid yang dapat berfungsi sebagai antibakteri. Masker gel peel off adalah sediaan kosmetik yang dapat dipilih sebagai perawatan kulit untuk mencegah timbulnya jerawat. Salah satu komponen masker gel peel off yang berperan dalam menentukan sifat fisik sediaan adalah basis gel. T

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Susanto, Fani, Kusnanto Mukti Wibowo, Alan Samudra, Puji Yuswono, Hernastiti Sedya Utami, and Edgardo Cayanan. "Pemanfaatan Getah Pelepah Salak Sebagai Gel Ultrasonografi Alternatif." Jurnal Imejing Diagnostik (JImeD) 11, no. 2 (2025): 6–12. https://doi.org/10.31983/jimed.v11i2.12551.

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Background: Conventional ultrasound (USG) gel was generally based on carbomer 940, which was relatively expensive, difficult to access in some areas, and not environmentally friendly due to its non-biodegradable nature. This study aims to evaluate the potential of salacca leaf sap as an alternative material for a more affordable, easily obtainable, and environmentally friendly natural ultrasound gel.Methods: A quantitative experimental study was conducted on 30 adult patients. Each subject underwent two liver ultrasound examinations using carbomer 940 gel and gel from salacca leaf sap. Image a

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Ayuningtyas, Nurista Dida, Agustina Putri Pitarisa Sudarsono, and Anastasiya Sisca Yuswanti. "Formulation of Toothpaste Toothpaste Gel Essential Oil of Lime Leaves (Citrus Aurantifolia) With Variations Concentration of Carbomer 940 As Gelling Agent Base." Jurnal Farmasi & Sains Indonesia 4, no. 2 (2021): 98–103. http://dx.doi.org/10.52216/jfsi.vol4no2p98-103.

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Background : Lime leaves contain flavonoids, tannins, and saponins. This content is known to have activity as an antibacterial and protective of gums and teeth. Based on these activities, lime leaves can be developed as an active ingredient in gel toothpaste preparations. In the manufacture of gel toothpaste, the component that plays an important role is the gelling agent. Purpose: In this study, a variation of the gelling agent Carbomer 940 will be used to make a gel toothpaste with lime leaf extract. Methods: The independent variable used is Carbomer 940 with a variation of 3 formulas, namel

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Surini, Silvia, Nurul Isti Amirtha, and Delly Chipta Lestari. "FORMULATION AND EFFECTIVENESS OF A HAND SANITIZER GEL PRODUCED USING SALAM BARK EXTRACT." International Journal of Applied Pharmaceutics 10, no. 1 (2018): 216. http://dx.doi.org/10.22159/ijap.2018.v10s1.48.

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Objective: The objectives of this study were to determine the minimum inhibitory concentration (MIC) of Salam bark extract against Staphylococcusaureus, formulate and evaluate hand sanitizer gels containing Salam bark extract, and determine the effectiveness of the gels against bacteria on thepalms of the hands.Methods: The gel base was optimized by preparing three formulations containing carbomer and triethanolamine at ratios of 0.25%:0.5%, 0.5%:1%,and 0.5%:2%. The best gel formulation was mixed with Salam bark extract. The physical stability of gels containing 4.04% (formulation 1) and 7.77%

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Anggun Hari Kusumawati and Siti Hufi Hutami. "PENGARUH VARIASI GELLING AGENT KARBOMER 934 EKSTRAK ETANOL DAUN JERUK PURUT (Citrus hystrix DC) TERHADAP SIFAT FISIK GEL DAN AKTIVITAS ANTIBAKTERI Staphylococcus aureus." Pharma Xplore : Jurnal Ilmiah Farmasi 4, no. 1 (2019): 248–59. http://dx.doi.org/10.36805/farmasi.v4i1.615.

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ABSTRAK Ekstrak etanolik daun jeruk purut (Citrus hystrix D.C) mempunyai banyak zat khasiat dimana salah satu zat aktif tersebut berkhasiat sebagai antibakteri. Penggunaan ekstrak etanolik dalam bentuk kental sangat tidak efisien dalam pemakaiannya, sehingga perlu dibuat dalam bentuk sediaan topical, misalnya gel. Penggunaan Karbomer 934 sebagai gelling agent dapat meningkatkan konsistensi basis yang akan berpengaruh terhadap pelepasan zat aktif di dalam gel. Penelitian ini bertujuan untuk mengetahui pengaruh variasi kadar basis Karbomer 934 gel ekstrak etanolik daun jeruk purut terhadap

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Varshosaz, Jaleh, Valiollah Hajhashemi, and Sindokht Soltanzadeh. "Lipid Nanocapsule-Based Gels for Enhancement of Transdermal Delivery of Ketorolac Tromethamine." Journal of Drug Delivery 2011 (November 17, 2011): 1–7. http://dx.doi.org/10.1155/2011/571272.

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Previous reports show ineffective transdermal delivery of ketorolac by nanostructured lipid carriers (NLCs). The aim of the present work was enhancement of transdermal delivery of ketorolac by another colloidal carriers, lipid nanocapsules (LNCs). LNCs were prepared by emulsification with phase transition method and mixed in a Carbomer 934P gel base with oleic acid or propylene glycol as penetration enhancers. Permeation studies were performed by Franz diffusion cell using excised rat abdominal skin. Aerosil-induced rat paw edema model was used to investigate the in vivo performance. LNCs cont

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Warnida, Husnul, Yullia Sukawaty, and Mega Mega. "STABILITAS DAN AKTIVITAS GEL EKSTRAK BULBUS BAWANG TIWAI (Eleutherine americana (Mill.) Urb.) SEBAGAI ANTI ACNE." Jurnal Ilmiah Manuntung 1, no. 1 (2017): 94. http://dx.doi.org/10.51352/jim.v1i1.19.

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awang Tiwai has an antibacterial activity toward some microorganisms e.g. Staphylococcus epidermidis dan Propionibacterium acne, two acne related bacteria. Bawang Tiwai extract 1% and 2% were formulated into gel (no oil content, because oil could make the acne worse) with carbomer 940 as gelling agent. Physical stability of bawang tiwai gel was evaluated included stability, organoleptic, pH, homogeneity, viscosity, consistency, spreading test, and activity toward Staphylococcus epidermidis. The result showed that all formulas are stable after 7 days. The test results of antibacterial activity

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Popova, Tetiana, Halyna Kukhtenko, Nataliia Bevz, and Oleksandr Kukhtenko. "Biopharmaceutical and rheometric studies in the development of a gel composition with dimethindene maleate." ScienceRise: Pharmaceutical Science, no. 3(31) (June 30, 2021): 11–18. http://dx.doi.org/10.15587/2519-4852.2021.234250.

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Every year there is an increase in the number of cases of hypersensitivity to bites from various insects. A local allergic reaction to bites occurs within a few minutes and is accompanied by acute pain at the site of the bite, severe itching, hyperemia, the appearance of papules, tissue edema, and sometimes a small-point rash around. Considering the small number of drugs for local therapy of allergic manifestations and the unidirectional nature of their action, it is urgent to develop a drug containing the antihistamine dimethindene maleate and dexpanthenol, which plays the role of an anti-inf

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Sandhiutami, Ni Made, Yesi Desmiaty, Fahleni Fahleni, Rizqya Handayani, and Windy Ciang. "Enhanced Anti-Inflammatory Activity of Passiflora edulis Leaf Extract Nanoparticle Gel in Carrageenan-Induced Rat Model." Sciences of Pharmacy 4, no. 1 (2025): 32–39. https://doi.org/10.58920/sciphar0401301.

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Passion fruit (Passiflora edulis) leaf extract is rich in flavonoids, which possess anti-inflammatory properties. This study aimed to enhance the anti-inflammatory effect of the extract through a nanoparticle gel formulation. Nanoparticles of the extract (NEP) were prepared using ionic gelation with a Carbomer 940 base. The anti-inflammatory efficacy of NEP was evaluated in vivo using a carrageenan-induced paw edema model in rats. Five groups (n=5) were tested: a negative control (Carbomer 940 gel base), a positive control (Sodium Diclofenac), and three NEP formulations with concentrations of

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Tetiana, Popova, Kukhtenko Halyna, Bevz Nataliia, and Kukhtenko Oleksandr. "Biopharmaceutical and rheometric studies in the development of a gel composition with dimethindene maleate." ScienceRise: Pharmaceutical Science, no. 3(31) (June 30, 2021): 11–18. https://doi.org/10.15587/2519-4852.2021.234250.

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Every year there is an increase in the number of cases of hypersensitivity to bites from various insects. A local allergic reaction to bites occurs within a few minutes and is accompanied by acute pain at the site of the bite, severe itching, hyperemia, the appearance of papules, tissue edema, and sometimes a small-point rash around. Considering the small number of drugs for local therapy of allergic manifestations and the unidirectional nature of their action, it is urgent to develop a drug containing the antihistamine dimethindene maleate and dexpanthenol, which plays the role of an anti-inf

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Alaa, Abdul-Rassol A., Mariee K. Nidhal, and Mehsin B. Masar. "Factors affecting the diffusion of meloxicam from different bases." Al Mustansiriyah Journal of Pharmaceutical Sciences 2, no. 2 (2005): 1–13. http://dx.doi.org/10.32947/ajps.v2i2.428.

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The value of meloxicam as a non-steroidal anti-inflammatory drug is well established. This study was carried out to formulate a stable and effective meloxicam topical preparation. The in vitro release of meloxicam from different semisolid bases, which are: o/w, w/o emulsions, sodium carboxy methylcellulose gel and carbomer gel base was established. The study also involved the diffusion of meloxicam through excised mouse skin with different concentrations using carbomer gel in addition to the effect of different enhancing agents such as PG (Propylene Glycol), methyl salicylate, urea, oleic acid

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Fathoni, Kristiani W. S. W., Hosea Jaya Edy, and Meilani Jayanti. "FORMULASI DAN EVALUASI VARIASI BASIS GEL AIR PERASAN TEMUAWAK (Curcuma xanthorrhiza R.) SEBAGAI ANTISEPTIK TANGAN." PHARMACON 10, no. 1 (2021): 655. http://dx.doi.org/10.35799/pha.10.2021.32751.

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ABSTRACT Temulawak (Curcuma xanthorrhiza R.) is a plant that contains antimicrobial properties of essential oil and curcumin compounds. The purpose of this study was to formulate temulawak juice into gel preparations by varying the HPMC and Carbomer gel bases with each base concentration of 1%, testing the effectiveness of the antiseptic preparations and evaluating the physical preparations of the gel. This study used laboratory experimental methods. temulawak is soaked in aquadest then filtered and centrifuged to obtain temulawak juice and formulated in a gel preparation. Testing the effectiv

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Mardikasari, Sandra Aulia, Arfian Junior Amir, Aliyah ., et al. "DEVELOPMENT OF METRONIDAZOLE MICROSPONGE INCORPORATED INTO CARBOMER-BASED VAGINAL GEL." Journal of Experimental Biology and Agricultural Sciences 9, Spl-2-ICOPMES_2020 (2021): S241—S247. http://dx.doi.org/10.18006/2021.9(spl-2-icopmes_2020).s241.s247.

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Bacterial vaginosis (BV) is a vaginal infection caused by excessive bacterial growth, thus disrupting the natural balance of bacteria inside the vagina. Metronidazole becomes a drug of choice and a widely prescribed drug for the treatment of BV. However, when applied topically, metronidazole has a low vaginal residence time because of the natural washing mechanism of the vagina. This study aimed to improve the retention time of metronidazole inside the vagina and control its release profile. This study was prepared 4 formulas of gel for metronidazole microsponges with some concentration ratio

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