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Dissertations / Theses on the topic 'Carbon ion therapy'

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1

Härtig, Martin Matthias [Verfasser], and Oliver [Akademischer Betreuer] Jäkel. "Motion Management for Carbon Ion Therapy at the Heidelberg Ion-Beam Therapy Center / Martin Matthias Härtig ; Betreuer: Oliver Jäkel." Heidelberg : Universitätsbibliothek Heidelberg, 2019. http://d-nb.info/120091872X/34.

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2

Härtig, Martin [Verfasser], and Oliver [Akademischer Betreuer] Jäkel. "Motion Management for Carbon Ion Therapy at the Heidelberg Ion-Beam Therapy Center / Martin Matthias Härtig ; Betreuer: Oliver Jäkel." Heidelberg : Universitätsbibliothek Heidelberg, 2019. http://d-nb.info/120091872X/34.

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3

Wieser, Hans-Peter [Verfasser], and Christian [Akademischer Betreuer] Karger. "Probabilistic Treatment Planning for Carbon Ion Therapy / Hans-Peter Wieser ; Betreuer: Christian Karger." Heidelberg : Universitätsbibliothek Heidelberg, 2020. http://d-nb.info/1222739607/34.

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4

Magallanes, Hernández Lorena [Verfasser], and Katia [Akademischer Betreuer] Parodi. "Low-dose ion-based transmission radiography and tomography for optimization of carbon ion-beam therapy / Lorena Magallanes Hernández ; Betreuer: Katia Parodi." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2017. http://d-nb.info/1126968358/34.

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5

Chanrion, Marie-Anne. "Study and development of physical models to evaluate biological effects of ion therapy : the study of local control of prostate cancer." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10304/document.

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La radiothérapie externe est un traitement anticancéreux locorégional efficace et curatif. Néanmoins, il y a toujours des malades qui meurent de tumeurs locales non-contrôlées. Les nouvelles techniques en radiothérapie visent toujours à trouver un moyen d'augmenter la dose à la tumeur tout en réduisant au minimum la dose aux tissus sains adjacents. Une des dernières techniques innovantes est l'hadronthérapie par ions carbone. Ces dix dernières années ont vu augmenter le nombre de nouveaux centres d hadronthérapie dans le monde avec des faisceaux d'ions carbone, forts des résultats promettant d
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6

Dahlgren, David. "Monte Carlo simulations of Linear Energy Transfer distributions in radiation therapy." Thesis, Uppsala universitet, Högenergifysik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-446550.

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In radiotherapy, a quantity asked for by clinics when calculating a treatment plan, along withdose, is linear energy transfer. Linear energy transfer is defined as the absorbed energy intissue per particle track length and has been shown to increase with relative biologicaleffectiveness untill the overkilling effect. In this master thesis the dose averaged linear energytransfer from proton and carbon ion beams was simulated using the FLUKA multi purposeMonte Carlo code. The simulated distributions have been compared to algorithms fromRaySearch Laboratories AB in order to investigate the agreem
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7

Wolf, Moritz Ernst [Verfasser], Marco [Akademischer Betreuer] Durante, and Christoph [Akademischer Betreuer] Bert. "Robust optimization in 4D treatment planning for carbon ion therapy of lung tumors / Moritz Ernst Wolf ; Marco Durante, Christoph Bert." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2018. http://d-nb.info/1176107615/34.

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8

Frese, Malte Christian [Verfasser], and Uwe [Akademischer Betreuer] Oelfke. "Potentials and Risks of Advanced Radiobiological Treatment Planning for Proton and Carbon Ion Therapy / Malte Christian Frese ; Betreuer: Uwe Oelfke." Heidelberg : Universitätsbibliothek Heidelberg, 2011. http://d-nb.info/1179229266/34.

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9

Kamp, Florian [Verfasser], Jan J. [Akademischer Betreuer] Wilkens, and Franz [Akademischer Betreuer] Pfeiffer. "Uncertainties in biological dose response models and their integration in treatment planning of carbon ion therapy / Florian Kamp. Gutachter: Jan J. Wilkens ; Franz Pfeiffer. Betreuer: Jan J. Wilkens." München : Universitätsbibliothek der TU München, 2015. http://d-nb.info/1069127795/34.

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10

Anderle, Kristjan [Verfasser], and Marco [Akademischer Betreuer] Durante. "In Silico Comparison of Photons versus Carbon Ions in Single Fraction Therapy of Lung Cancer / Kristjan Anderle. Betreuer: Marco Durante." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2016. http://d-nb.info/1112332944/34.

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11

Bencini, Vittorio. "Design of a novel linear accelerator for carbon ion therapy." Doctoral thesis, 2020. http://hdl.handle.net/11573/1364636.

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Hadron therapy has been first proposed in 1946 by Robert Wilson as an advanced form of radiotherapy. Hadrons, such as protons and light ions, release the largest part of their energy in a narrow space range, called Bragg peak, allowing to target the tumor cells more precisely than photon beams. Despite this advantage, the number of proton and carbon ion therapy centers is still small compared to conventional radiotherapy. One of the reasons for this disparity can be found in the treatment costs of hadron therapy, which is three to four times higher than for conventional radiotherapy, due to th
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12

Butkus, Michael Patrick. "Determination of Dose From Light Charged Ions Relevant to Hadron Therapy Using the Particle and Heavy Ion Transport System (PHITS)." Thesis, 2011. http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-9861.

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In conventional radiotherapy for tumor treatment, photons are used to impart an energetic dose inside a tumor with the goal of killing the cancerous cells. This process is intrinsically inefficient due to the fact that photons lose their energy exponentially with depth causing the highest dose to occur in overlying healthy tissue. However, charged particles with a mass of 1 amu or greater lose their energy in a manner that allows for a high dose to be localized at significant depth. The area of high dose localization is known as the Bragg Peak. Exploitation of the Bragg Peak could lead to
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13

Curtis, Keel Brandon. "Computer Simulation and Comparison of Proton and Carbon Ion Treatment of Tumor Cells Using Particle and Heavy Ion Transport Code System." 2010. http://hdl.handle.net/1969.1/ETD-TAMU-2010-12-8689.

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Charged particle beams are an increasingly common method of cancer treatment. Because of their Bragg peak dose distribution, protons are an effective way to deliver a dose to the tumor, while minimizing the dose to surrounding tissue. Charged particles with greater mass and higher charge than protons have an even sharper Bragg peak and a higher Relative Biological Effectiveness (RBE), allowing a greater dose to be delivered to the tumor and sparing healthy tissue. Since carbon ions are being implemented for treatment in Europe and Japan, this study will focus on carbon as the heavier ion of ch
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14

Wolf, Moritz Ernst. "Robust optimization in 4D treatment planning for carbon ion therapy of lung tumors." Phd thesis, 2018. https://tuprints.ulb.tu-darmstadt.de/8354/1/phd_thesis_mowolf_final_publish.pdf.

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Particle therapy (PT) with scanned carbon ions has been shown to improve the treatment of stage IV lung cancer patients through reduced dose exposure of critical organs. In order to maximize this effect, the application of intensity modulated particle therapy (IMPT) is needed. However, PT is particularly susceptible to internal dose gradients due to its range dependence. This challenge is exacerbated in the presence of organ motion. Both, motion and internal dose gradients, can be addressed by dedicated robust 4D optimization strategies. In addition, as IMPT needs congruent target volumes, on
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15

Lai, Bo-Lun, and 賴柏倫. "Radiation Field Characterization and Shielding Studies on Proton, Carbon-ion, and Accelerator-Based Boron Neutron Capture Therapy Facilities." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/597apf.

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16

Qamhiyeh, Sima [Verfasser]. "A Monte Carlo study of the accuracy of CT-numbers for range calculations in carbon ion therapy / presented by Sima Qamhiyeh." 2007. http://d-nb.info/984390839/34.

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17

von, Neubeck Cläre. "Radiobiological experiments for carbon ion prostate cancer therapy: Interplay of normal and tumor cells in co-culture and measurement of the oxygen enhancement ratio." Phd thesis, 2009. https://tuprints.ulb.tu-darmstadt.de/1973/1/Cl%C3%A4re_PhD.pdf.

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Co-culture models are helpful to examine cell to cell interactions in vitro and to assess the cross-communication between two particular cell populations. Co-culture systems partially reflect the complex in vivo situation: in this study an in vitro co-culture model of prostate cancer cells {(Dunning R-3327-AT-1)} and small intestine cells {(intestinal epithelium cell line 6)} of the rat was established to simulate the carbon ion treatment of prostate cancer patient at GSI. Both cell lines were characterized in mono-cultures for their radio-biological response against 250 kVp x-rays and carbon
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18

Neubeck, Cläre von [Verfasser]. "Radiobiological experiments for carbon ion prostate cancer therapy : interplay of normal and tumor cells in co-culture and measurement of the oxygen enhancement ratio / von Cläre von Neubeck." 2009. http://d-nb.info/999116827/34.

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19

Anderle, Kristjan. "In Silico Comparison of Photons versus Carbon Ions in Single Fraction Therapy of Lung Cancer." Phd thesis, 2016. https://tuprints.ulb.tu-darmstadt.de/5567/1/main.pdf.

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Stereotactic body image guided radiation therapy (SBRT) shows excellent results for the local control of early stage lung cancer. However, not all patients are eligible for SBRT, and advanced stage treatment is less successful and often associated with severe side effects. Scanned carbon ion therapy (PT) can deliver more conformal dose likely benefiting these patient groups. Therefore an \textit{in silico} trial was conducted on early and advanced stage patients to identify potential advantages of PT. The patients were treated with SBRT at Champalimaud Center for the Unknown, Lisbon (
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20

Rahm, Johannes Martin. "Measurement of the stopping power of water for carbon ions in the energy range of 1 MeV - 6 MeV using the inverted Doppler–shift attenuation method." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-002B-7CCE-6.

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