Academic literature on the topic 'Carbon Tetrachloride (CCL4)'

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Journal articles on the topic "Carbon Tetrachloride (CCL4)"

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Boll, Meinrad, W. D. Lutz, Eberhard Becker, and Andreas Stampfl. "Mechanism of Carbon Tetrachloride-Induced Hepatotoxicity. Hepatocellular Damage by Reactive Carbon Tetrachloride Metabolites." Zeitschrift für Naturforschung C 56, no. 7-8 (2001): 649–59. http://dx.doi.org/10.1515/znc-2001-7-826.

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CCl4-induced liver damage was modeled in monolayer cultures of rat primary hepatocytes with a focus on involvement of covalent binding of CCl4 metabolites to cell components and/or peroxidative damage as the cause of injury.(1) Covalent binding of 14C-labeled metabolites was detected in hepatocytes immediately after exposure to CCl4. (2) Low oxygen partial pressure increased the reductive metabolism of CCl4 and thus covalent binding. (3) [14C]-CCl4 was bound to lipids and to proteins throughout subcellular fractions. Binding occurred preferentially to triacylglycerols and phospholipids, with p
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Yamashiro, S., T. Bast, R. A. Towner, E. G. Janzen, and L. A. Reinke. "Role of Kupffer cells in CCl4-induced hepatocytic toxicity: A preliminary study." Proceedings, annual meeting, Electron Microscopy Society of America 51 (August 1, 1993): 392–93. http://dx.doi.org/10.1017/s042482010014779x.

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Carbon tetrachloride (CCl4) hepatotoxicity is one of the most frequently used experimental models to study the mechanism of cell damage by metabolites of xenobiotics (1,2). Cytochrome P-450 enzymes are considered to be involved in the metabolic activation of CCl4 to generate the trichloromethyl (.CCl3), which in turn may be converted to the peroxy radical (.00-CCl3) (3,4). In our previous studies, we have demonstrated CCl4-induced edematous response by using proton magnetic resonance imaging and electron microscopy (2,5). However, these studies have not given any consideration to Kupffer cells
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Dwirini Retno Gunarti, Reni Paramita, Syailendra Karuna Sugito, and Istiqomah Agusta. "Rice brain administration reduces malondialdehyde (MDA) levels in the heart of carbon tetrachloride-induced rats." World Journal of Biology Pharmacy and Health Sciences 18, no. 2 (2024): 403–9. http://dx.doi.org/10.30574/wjbphs.2024.18.2.0307.

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Excessive production of free radicals proven associated with disease progression of coronary heart disease. Rice bran oil has a high content of antioxidants such as tocopherol, tocotrienol, and γ-oryzanol. This study aimed to determine the effect of rice bran oil administration on malondialdehyde (MDA) level as an oxidative stress biomarker in the heart of carbon tetrachloride (CCl4)-induced rats. Thirty stored rat heart tissue samples that were divided into six groups, consisted of untreated control group, CCl4-treated group (CCl), rice bran oil-treated before CCl4 induction groups with rice
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Adebukola, Adeyanju Anne. "Protective Effect of Protocatechuic Acid in Genotoxicity-Induced by Carbon Tetrachloride: A Preliminary Study." Advances in Clinical Toxicology 8, no. 3 (2023): 1–5. http://dx.doi.org/10.23880/act-16000273.

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Carbon tetrachloride (CCl4) is commonly utilized as a solvent, a refrigerant, and a dry-cleaning agent. However, its genotoxic effect has been well documented. The present work was designed to assess the genotoxic effect of carbon tetrachloride in the bone marrow of rats. The safety and the possible protective effect of protocatechuic acid (PCA) in the genotoxicity induced by carbon tetrachloride (CCl4) were evaluated using a micronucleus assay. Rats were divided into six groups where groups I and II served as the control. Group III was exposed to CCl4 only at 3mL/kg intraperitoneally. Groups
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Firdous, Sayeed Mohammad, and Marwa A. A. Fayed. "Effects of Medicinal Plants on Carbon Tetrachloride-Induced Liver Injury: A Review." INNOSC Theranostics and Pharmacological Sciences 4, no. 2 (2023): 23–32. http://dx.doi.org/10.36922/itps.v4i2.215.

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The liver is the primary organ for metabolizing and eliminating foreign chemicals. When liver cells are exposed to large concentrations of dangerous substances, hepatocyte malfunction, membrane damage, and degradation may occur. Another chemical that can harm the liver is carbon tetrachloride (CCl4). CCl4 is converted into trichloromethyl radical [CCl3]- by several cytochrome P450 isoforms. [CCl3]- subsequently reacts with oxygen to generate trichloromethyl peroxyl radical [CCl3OO]- and induce lipid peroxidation in cell membranes. In this study, the mechanism by which a variety of recently ide
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Hsieh, Chien Te, Jin Ming Chen, Yue Hao Huang, Rong Rong Kuo, Chung Tien Li, and Han Chang Shih. "Adsorptive Surface Coverage of Carbon Tetrachloride onto Carbon Nanofibers Array." Solid State Phenomena 121-123 (March 2007): 417–24. http://dx.doi.org/10.4028/www.scientific.net/ssp.121-123.417.

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This work explores an estimation of adsorptive surface coverage for carbon tetrachloride onto different carbon nanofibers (CNFs). Two kinds of CNFs with various pore characteristics are fabricated by template-based and thermal chemical vapor deposition methods, respectively. The pore size distributions of these carbons, determined according to the density functional theory model, are found to vary with synthesis methods. The results of adsorption experiments show that CCl4 adsorption isotherms of these CNFs are of Langmuir-type model during the restricted pressure of 0–0.2 atm at 30°C. The sur
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Mughal, Tafail Akbar, Shaukat Ali, Shazia Khatoon, Saeed Khalil, and Shumaila Mumtaz. "Protective effect of Helianthus annuus seeds extract against CCl4-induced hepatocellular damage." Pakistan Journal of Biochemistry and Biotechnology 4, no. 2 (2023): 37–45. http://dx.doi.org/10.52700/pjbb.v4i2.97.

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Carbon tetrachloride (CCl4) is a hepatotoxin that causes toxicity in animals on its exposure. Hepatotoxins lead to hepatic demage that is treated by generating antioxidant effect. Synthetic and as well as natural drugs are available for this purpose but phyto-based herbal medicines got paramount importance against drug induced hepatotoxicity Current research was conducted to inspect the protective effect of aqueous extract of Helianthus annuus seeds pre-treatment on the carbon tetrachloride-induced hepatotoxicity in Balb C mice. Study covered the valuation of the enzymatic activity such as ala
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Fraser, Paul J., Bronwyn L. Dunse, Alistair J. Manning, et al. "Australian carbon tetrachloride emissions in a global context." Environmental Chemistry 11, no. 1 (2014): 77. http://dx.doi.org/10.1071/en13171.

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Environmental context Carbon tetrachloride in the background atmosphere is a significant environmental concern, responsible for ~10% of observed stratospheric ozone depletion. Atmospheric concentrations of CCl4 are higher than expected from currently identified emission sources: largely residual emissions from production, transport and use. Additional sources are required to balance the expected atmospheric destruction of CCl4 and may contribute to a slower-than-expected recovery of the Antarctic ozone ‘hole’. Abstract Global (1978–2012) and Australian (1996–2011) carbon tetrachloride emission
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Naz, Sana, Faisal Irshad, and Hina Mawani. "CCl4 INDUCED LIVER INJURY;." Professional Medical Journal 24, no. 05 (2018): 739–44. http://dx.doi.org/10.29309/tpmj/2017.24.05.1298.

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Objectives: Evaluate the mitigating effect of aqueous extract of Ginkgobiloba (GkbE) on liver enzymes and histology in carbon tetrachloride (CCl4) induced liverinjury in albino rat. Study design: Experimental study. Setting and Duration: Animal house,Bhitai Dental and Medical College Mirpurkhas and Agriculture University Tando Jam fromAnimal house from May 2015 - August 2016. Subjects and Methods: Sixty rats were equallydivided into 3 groups Group 1- Controls (0.9% isotonic saline), Group 2- (CCl4 CCl4 1.0mg/kg intraperitoneal) and Group 3- (CCl4+ GkbE). Blood samples were collected at end ofe
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Liu, Hsu-Jan, Sheng-Feng Hsu, Chang-Chi Hsieh, et al. "The Effectiveness of Tsu-San-Li (St-36) and Tai-Chung (Li-3) Acupoints for Treatment of Acute Liver Damage in Rats." American Journal of Chinese Medicine 29, no. 02 (2001): 221–26. http://dx.doi.org/10.1142/s0192415x01000253.

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This study investigated the effects of acupuncture on carbon tetrachloride (CCl4) induced acute liver injury in male rats (n = 36). The experimental groups were injected with CCl4 before, during, or after acupuncture therapy. Acupoints similar to the human Tsu-San-Li (St-36) and Tai-Chung (Li-3) were needled bilaterally. Rats treated with CCl4 had higher levels of serum glutamate-oxalate-transaminase (sGOT) and serum glutamate-pyruvate-transaminase (sGPT). Comparing the experimental groups, biochemical and pathological parameters of liver injury were significantly reduced when rats were acupun
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Dissertations / Theses on the topic "Carbon Tetrachloride (CCL4)"

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Gao, Yong. "Noninvasive monitoringn of CCl4 induced acute and chronic liver damage in rat by single quantum and triple quantum filtered 23Na magnetic resonance imaging." Connect to resource online, 2008. http://hdl.handle.net/1805/2045.

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Thesis (M.S.)--Indiana University, 2008.<br>Title from screen (viewed on January 26, 2010). Department of Cellular & Integrative Physiology, Indiana University-Purdue University Indianapolis (IUPUI). Advisor(s): Navin Bansal, Andriy M. Babsky, Stephen A. Kempson, David P. Basile. Includes vitae. Includes bibliographical references (leaves 33-36).
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GADIPUDI, LAILA LAVANYA. "Macrophage Phenotype during Liver Injury and Repair." Doctoral thesis, Università del Piemonte Orientale, 2022. http://hdl.handle.net/11579/142900.

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Manno, Maurizio. "Studies on the mechanism of suicidal inactivation of cytochrome P-450 by carbon tetrachloride." Thesis, University of Surrey, 1989. http://epubs.surrey.ac.uk/847771/.

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1. The molecular mechanism and the reactive species involved in the inactivation of microsomal cytochrome P-450 during the reductive metabolism of carbon tetrachloride (CCl[4]) were studied. Results obtained with spectrophotometric, fluorimetric and chromatographic methods and using strictly anaerobic conditions indicate that the prosthetic group of the cytochrome, haem, is both the site and the target of CCl4 activation. 2. Stoichiometric losses of microsomal haem and cytochrome P-450 were observed when CCl[4] was incubated anaerobically with NADPH- or sodium dithionite-reduced rat liver micr
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Pittaya, Kanchanapakonchai Amnuay Thithapandha. "Effects of vitamin B6 on CC14 toxicities in rats /." abstract, 1986. http://mulinet3.li.mahidol.ac.th/thesis/2529/29E-Pittaya-K.pdf.

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Barnes, Mark Aaron Jr. "MACROPHAGE MIGRATION INHIBITORY FACTOR AND LIVER DISEASE: THE ROLE OF MIF IN ALCOHOL-INDUCED LIVER INJURY AND CARBON TETRACHLORIDE (CCI4)-INDUCED LIVER FIBROSIS." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1396429556.

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Nasri, Ridha. "Conception et réalisation d'un adaptateur haute impédance programmable : epplication à la caractérisation de liquides magnétiques." Saint-Etienne, 1994. http://www.theses.fr/1994STET4014.

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Ce travail s'inscrit dans le cadre de la recherche sur les ferrofluides ou liquides magnétiques. Les évolutions, qui peuvent être rapides, des propriétés diélectriques de ces matériaux telles que les changements de phase du liquide porteur, la perte d'homogénéité par formation d'agrégats ou de multicouches nécessitent l'automatisation complète de l'acquisition des mesures. Pour cela, nous avons développé autour d'un analyseur vectoriel, un adaptateur haute impédance programmable en mode shunt fonctionnant dans la gamme 1mhz-10khz. Cette réalisation fait appel à l'électronique haute impédance :
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Gao, Yong. "NONINVASIVE MONITORING OF CCl4 INDUCED ACUTE AND CHRONIC LIVER DAMAGE IN RAT BY SINGLE QUANTUM AND TRIPLE QUANTUM FILTERED 23Na MAGNETIC RESONANCE IMAGING." Thesis, 2008. http://hdl.handle.net/1805/2045.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>In present study, single quantum (SQ) and triple quantum filtered (TQF) 23Na magnetic resonance imaging (MRI) was used to monitor the severity and progression of CCl4 induced acute and chronic liver damage in rat model. SQ 23Na MRI was proposed to measure the 23Na signal intensity (SI) of total tissue sodium ions, and TQF 23Na MRI was proposed to measure the SI of intracellular sodium ions. In addition, shift reagent aided 23Na and 31P magnetic resonance spectroscopy (MRS) was used to measure in vivo intracellular sodium concentrat
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Tzeng, Cheng-Wei, and 曾承煒. "Solid fermented Antrodia cinnamomea inhibit acute and chronic hepatic injury induced by carbon tetrachloride (CCl4) and quality assessment." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/94202848024195368065.

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碩士<br>高雄醫學大學<br>天然藥物研究所<br>96<br>Antrodia cinnamomea, an endemic fungus in Taiwan, is well-known as a folk medicine, it grows only on the inner heartwood wall of the endemic evergreen Cinnamonum kanehirai and can not be cultivated. It has much physiological activities, including antioxidant, anticancer and hepatoprotective activity, and has active constituents that have anti-hepatitis B virus activity. The purpose of this research is to evaluate the hepatic protective effect of solid fermented A. cinnamomea against carbon tetrachloride (CCl4)-induced acute and chronic hepatic injury in vivo. I
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Book chapters on the topic "Carbon Tetrachloride (CCL4)"

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Bursch, W., and R. Schulte-Hermann. "Cytoprotective Effect of Iloprost Against Liver Cell Death Induced by Carbon Tetrachloride (CCl4) or Bromobenzene." In Prostacyclin and Its Stable Analogue Iloprost. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71499-3_27.

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Sujatha, K., V. Karthikeyan, R. S. Ponmagal, et al. "Hepatoprotective Activity of the Biherbal Extract in Carbon Tetrachloride (CCl4) Induced Hepatoxicity—A Study of Histopathological Image Analysis." In Intelligent Systems, Technologies and Applications. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6095-4_20.

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"Carbon Tetrachloride (CCl4)." In Gaseous Electronics. CRC Press, 2011. http://dx.doi.org/10.1201/b11492-56.

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Kumar Jain, Neetesh, and Nitu Singh. "Hepatoprotective Role of Herbs and Herbal Formulations." In Plant-derived Hepatoprotective Drugs. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815079845123010006.

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The liver is an important organ in the body's metabolism and excretory system. The prevalence of many forms of hepatic illnesses is on the rise, resulting in a major increase in morbidity and mortality worldwide. Viral hepatitis, alcoholic/non-alcoholic fatty liver disease, liver fibrosis, cirrhosis, hepatocellular cancer, and drug-induced liver injury are all important health concerns that take millions of lives each year throughout the world. Pharmaceutical medications are frequently linked to liver injury, and so have limited efficacy in the treatment of liver diseases. As a result, herbal
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Darbar, Soumendra, Atiskumar Chattopadhay, Kausikishankar Pramanik, and Srimoyee Saha. "Unprecedented redox scavenging signature along with antioxidant action of silver nanoparticle coupled with Andrographis paniculata (AP-Ag NP) against carbon tetrachloride (CCl4) induced toxicity in mice." In Biotechnology and Biological Sciences. CRC Press, 2019. http://dx.doi.org/10.1201/9781003001614-10.

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Conference papers on the topic "Carbon Tetrachloride (CCL4)"

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Matić, Sanja, Pavle Mašković, and Katarina Šipovac. "DNA PROTECTIVE ACTIVITY OF TWO SPECIES OF THE „SCROPHULARIA“ GENUS 2021ICCBIKG (2021)." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.218m.

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Plants from the genus Scrophularia, family Scrophulariaceae have numerous biological activities such as antibacterial, antioxidant, antiprotozoal, antitumor, hepatoprotective, and antidiabetic. However, as far as we know, genotoxic and antigenotoxic effects of these two plant species remain unexplored. The present study aimed to evaluate possible in vivo protective effects of the methanol extracts of two plant species of the Scrophularia genus, Scrophularia canina L. and S. alata Gilib., against carbon tetrachloride (CCl4)-induced DNA damage in albino Wistar rat. A significant increase in tota
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Ogunlana, Olubanke Olujoke, Oluseyi Ebenezer Ogunlana, Isaacson Bababode Adelani, et al. "Assessment of the hepatoprotective activity of the seeds of Hunteria umbellata (Hallier F.) on carbon tetrachloride (CCl4) induced liver damage in Wistar albino rats." In PROCEEDINGS OF THE 2ND INTERNATIONAL CONFERENCE ON APPLIED SCIENCES (ICAS-2). Author(s), 2018. http://dx.doi.org/10.1063/1.5033397.

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Rodriguez, R., and F. V. Wells. "Species Identification and Conversion Measurements in a Carbon Tetrachloride Radio Frequency Plasma Using Coherent Raman Techniques." In Laser Applications to Chemical Analysis. Optica Publishing Group, 1994. http://dx.doi.org/10.1364/laca.1994.wd.7.

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Radio frequency plasmas are used in the electronics industry in various phases of microcircuitry processing. Deposition and etching are two key areas where these types of plasmas are used. In recent past, carbon tetrachloride, CC14, has been used in the etching of metals such as aluminum. However, one of the problems associated with using this gas as an etchant is the formation of a glow polymer which coats the walls of the chamber and can interfere with the etching.
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