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Journal articles on the topic 'Carbopol 934 and Carbopol 940'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Anchal Dwivedi, Shriyanshi Singh Rana, Vishal Dubey, Megha Tiwari, Mayur Porwal, and Anita Devi. "Formulation and Evaluation of ACNE Gel using Metronidazole and Doxycycline." Journal of Advanced Zoology 44, S6 (2023): 72–79. http://dx.doi.org/10.17762/jaz.v44is6.1986.

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This research study focuses on the formulation and evaluation of an ACNE gel using Metronidazole (1%) and Doxycycline (0.5%) as active ingredients. Three types of polymers, Hydroxypropyl Methylcellulose (HPMC), Carbopol 940, and Carbopol 934 were used for gel formation. The formulated gels were evaluated for their physical characteristics, in vitro drug release, and drug-polymer compatibility. The calibration curves for both Metronidazole and Doxycycline displayed strong linearity within the concentration range of 5 to 25 µg/mL, facilitating accurate drug quantification. The gel formulations e

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Vasudev, Jitendra Sharma* Mayur Gokul Jayswal Raza Khan Dr. Mohd. Rehan Deshmukh Prof. (Dr.) G. J. Khan. "Formulation And Evaluation of Gel Containing Zinc Oxide Nanoparticle of Ketoconazole With Aqueous Honey Solution." International Journal in Pharmaceutical Sciences 1, no. 10 (2023): 44–53. https://doi.org/10.5281/zenodo.8419318.

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The aim and objective of the present study was to formulate and evaluate Ketoconazole Nanoparticle. Prepared Ketoconazole loaded zinc oxide nanoparticle. The prepared Nanoparticle formulation was evaluated for particle size and Polydispersity index. The prepared Nanoparticle further formulation gel was prepared with Carbopol 934 and Carbopol 940 Polymers. The honey used as antimicrobial and antifungal agent. The prepared Formulation was evaluated Drug content, viscosity. Spreadability, pH, In vitro Drug release study and Stability studies, antifungal activity. Particle size analysis showed tha

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Sonali, Verma1* Sandhya2. "Formulation And Development And In Vitro Evaluation Of Ocimum Sanctum Leave Microemulgel For Antioxidant Activity." International Journal in Pharmaceutical Sciences 2, no. 9 (2024): 27–38. https://doi.org/10.5281/zenodo.13871143.

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This study aimed to formulate and evaluate Microemulgel loaded with Ocimum sanctum leaf extract for antioxidant activity. Leaves were extracted using methanol, ethanol, and water, with ethanol providing the highest yield. The phytochemical analysis demonstrated the presence of bioactive compounds like alkaloids, flavonoids, terpenoids, and steroids in the extracts. Three formulations of Microemulgel were developed using different polymers - Carbopol 934, Carbopol 940, and HPMC. The formulated Microemulgel exhibited desirable properties including slightly acidic pH, high viscosity, and good spr

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Pranay, Sawant* Tejas Sutar Sayali Sawant Susmita Holmukhe. "Design and Assessment of Mucoadhesive Insitu Gel Forming Spray for Oral Delivery of Ibuprofen." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 3263–76. https://doi.org/10.5281/zenodo.15288007.

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The present study was aimed to develop an insitu gel forming spray for local release of Ibuprofen in the buccal cavity to improve the analgesic effect of NSAID drug which has poor water solubility. The formulations were introduced to the oral cavity as a spray to improve compliance and for easier administration. In this work, two grades of Carbopol (934 and 940)-based in situ gel spray were designed. The formulations containing Ibuprofen spray prepared by mixing different concentrations of Carbopol with xanthan gum. Four formulations were investigated and evaluated for pH, gelation capacity, s

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Lütfi, Genç, Hegazy Nahed, and Arica Betül. "Investigation of certain varieties of carbopol in ketorolac tromethamine hydrophilic matrix tablet formulations and evaluation of the kinetics of its in vitm release." Scientia Pharmaceutica 70, no. 2 (2002): 189–98. http://dx.doi.org/10.3797/scipharm.aut-02-20.

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Matrix tablets of ketorolac trometharnine (KT) were prepared by direct compression technique and Carbopol 934, 940 and 1342 have been used as polymers in different concentrations (5-15 % ). For the quality control of tablets; physical tests as crushing strength, diameter-height ratio and fkiability, KT amount assay and in vitro dissolution techniques were performed and dissolution profiles were plotted and evaluated kinetically. The in vitro release kinetics of ten different formulations of KT matrix tablet were studied at pH 1.2 and pH 7.0 using the USP dissolution technique and apparatus wit

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Sulaiman, Halah Talal, Saba Abdulhadi Jabir, and Khalid Kadhem Al-kinani. "INVESTIGATING THE EFFECT OF DIFFERENT GRADES AND CONCENTRATIONS OF PH‑SENSITIVE POLYMER ON PREPARATION AND CHARACTERIZATION OF LIDOCAINE HYDROCHLORIDE AS IN SITU GEL BUCCAL SPRAY." Asian Journal of Pharmaceutical and Clinical Research 11, no. 11 (2018): 401. http://dx.doi.org/10.22159/ajpcr.2018.v11i11.28492.

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Objective: The present study was aimed to develop a pH-triggered in situ gel for local release of lidocaine hydrochloride (lidocaine HCL) in the buccal cavity to improve the anesthetic effect of this amino amide drug which has very high water solubility. The formulations were introduced to the oral cavity as a spray to improve compliance and for easier administration.Methods: In this work, two grades of carbopol (934 and 940)-based in situ gel spray were designed. The formulations containing lidocaine HCl 5% were prepared by mixing different concentrations of carbopol with xanthan gum. Eight f

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Al-Sakini, Sadeq Jaafar, and Nidhal K. Maraie. "In vitro Evaluation of the Effect of Using Different Gelling agents on the Release of Erythromycin from a Nanocubosomal gel." Al Mustansiriyah Journal of Pharmaceutical Sciences 19, no. 1 (2019): 34–43. http://dx.doi.org/10.32947/ajps.v19i1.542.

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Preparation of a topical gel for erythromycin using optimized nano-sized cubosome dispersion, which is changed into a gel to get nanocubosomal gel using different gelling agents. The optimum nanocubosomal dispersion containing 4.4% glyceryl mono oleate (GMO) (as an oil phase) and 0.6% poloxamer 407 (as an emulsifying agent) was converted into a gel using different gelling agents including carbopol 974, carbopol 940, carbopol 934 and hydroxyl propyl methylcellulose (HPMC) at different ratios of (1:1 and 1:2). Each prepared gel was then evaluated in vitro to determine the homogenisity, con

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Kadhium, Huda S., and Nidhal K. Maraie. "Efficacy of Gelling Agents on the In-vitro Release and Physical Properties of Loxoprofen Sodium Gel Containing Ultra Elastic Vesicles." International Journal of Drug Delivery Technology 9, no. 04 (2019): 671–77. http://dx.doi.org/10.25258/ijddt.9.4.26.

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Objective: Preparation of a topical prolong release gel for loxoprofen sodium using optimized nano-sized transfersome dispersion using different gelling agents with in vitro and in vivo evaluation in comparison to the marketed gel prepared by a conventional method. Method: The optimum nano transfersome dispersion containing 5% egg lecithin (as an oil phase) 1% span 60 (as an emulsifying agent) was converted into a gel using different gelling agents including carbopol 974p, carbopol 940, carbopol 934 and hydroxyl propyl methylcellulose (HPMC K100) at ratio of (1:1). Each prepared gel was then e

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Sharma, Aditya, Jashanpreet Kaur, and Anju Goyal. "Carbopol 940 Vs Carbol 904: A better Polymer for Hydrogel formulation." RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY 14, no. 3 (2021): 1561–64. http://dx.doi.org/10.5958/0974-360x.2021.00275.4.

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Nikam, Pratiksha, Dr Sanjay B. Bais Dr.Sanjay B. Bais, and Dr Javesh K Patil. "Formulation and Evaluation of Apple Peel and Goldensealroot Combine Extract Gel." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 118–26. https://doi.org/10.35629/4494-1002118126.

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This study focuses on the formulation and evaluation of gel formulations combining extracts of Apple peel and Goldenseal, known for their potent phytochemical properties. Various gelling agents including Carbopol 934, Carbopol 940, Hydroxy Propyl Methyl Cellulose (HPMC), and Sodium Carboxy Methyl Cellulose (Na CMC) were employed at varying concentrations to develop stable gels. The formulations were characterized for homogeneity, pH, viscosity, extrudability, and spreadability. The in vitro release profile of the gels was assessed using Franz diffusion cells, and the antioxidant activity was e

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Gosavi, Akshata Anil, Priyanka Abaso Thorat, and Jameel Ahmed S. Mulla. "Formulation and Evaluation of Acyclovir Loaded Transferosomal Gel for Transdermal Drug Delivery." Journal of Drug Delivery and Therapeutics 14, no. 9 (2024): 122–30. http://dx.doi.org/10.22270/jddt.v14i9.6786.

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Background: A carrying structure for targeted transdermal drug delivery is a transferosome. These unique liposomes are made of an edge activator and phosphatidylcholine. The most common antiviral drug is acyclovir, a synthetic nucleotide nucleoside analog derived from guanine. It works well to cure the varicella-zoster virus and the virus that causes herpes simplex (HSV), primarily HSV-1 and HSV-2. But its skin permeability is minimal. Therefore, this work aimed to use transferosomes to prepare acyclovir so that it could pass through the skin's barrier function. Objective: This study uses a 32

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., Vinod L. Gaikwad, Vishal D. Yadav ., Rakesh P. Dhavale ., Prafulla B. Choudhari ., and Swapnil D. Jadhav . "Effect of Carbopol 934 and 940 on Fluconazole Release from Topical Gel Formulation: A Factorial Approach." Journal of Current Pharma Research 2, no. 2 (2012): 487–93. http://dx.doi.org/10.33786/jcpr.2012.v02i02.004.

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Parul, Nigam, and Mishra Sonam. "Nyctanthes arbor tristis Fruit Emulgel: Formulation, Evaluation, and Potential for Osteoarthritis Management." PEXACY International Journal of Pharmaceutical Science 6, no. 1 (2023): 41–60. https://doi.org/10.5281/zenodo.8213505.

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Abstract: Osteoarthritis is a common and debilitating degenerative joint disorder affecting millions of individuals worldwide. Managing osteoarthritis remains a challenge, necessitating the exploration of novel and effective therapeutic approaches. In recent years, natural products derived from medicinal plants have gained significant attention for their potential as alternative treatments due to their anti-inflammatory and analgesic properties. The Emulgel formulations are prepared with Carbopol 940, Carbopol 934, and Hydroxypropyl Methylcellulose (HPMC) as gelling agents to impart stability

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Misbah, Khanum Dr. C.S.R. Lakshmi. "Development and Evaluation of Nanoparticles Based Topical Gel Containing Antifungal Drug Fluconazole." International Journal Of Pharmaceutical And Bio-Medical Science 01, no. 09 (2021): 181–91. https://doi.org/10.47191/ijpbms/v1-i9-02.

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The objective of this work was to prepare Fluconazole nanoparticles, and then incorporated into the freshly prepared gel for transdermal delivery, reducing the oral side effects of the drug and forenhancing stability. Fluconazole is commonly used antifungal agents for the treatment of local and systemic fungal infections. In this study Fluconazole nanoparticles was prepared by usingEudragit RL 100 by nanoprecipitation method with different drugs to polymer (1:1, 1:2 and 1:3) and stabilizer (Poloxamer 188) ratios (0.5%, 0.75% and 1%) and evaluated for various parameters.Drug-excipients compatib

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Singh, Navdeep, Kamya Goyal, Shivi Sondhi, and Shammy Jindal. "Development and Characterization of Barbaloin Gel for the Safe and Effective Treatment of Psoriasis." Journal of Drug Delivery and Therapeutics 10, no. 5 (2020): 188–97. http://dx.doi.org/10.22270/jddt.v10i5.4299.

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Psoriasis is an inflammatory skin disease which cause inflammation to the skin and generally the symptoms includes white or red colour of irregular skin; the patches are developed and they are commonly itchy and scaly to the skin. Barbaloin is an herbal phytoconstituent which is obtained from the plant aloe vera leaf part. In the present study hydrogels formulation batches from F1 to F10 were prepared by using carbopol 934, Xanthan gum, carbopol 940, and carbopol 71G NF as a gelling agent. The prepared formulations from F1 to F10 were evaluated for their physical appearance, Grittiness, spread

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Usmania*, Ajay Bilandi Mahesh K. Kataria. "FORMULATION AND EVALUATION OF MINOXIDIL EMULGEL FOR ANDROGENIC ALOPECIA." csk publications 03, no. 12 (2017): 1593–610. https://doi.org/10.5281/zenodo.258181.

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Androgenic alopecia is the loss of hair, pertains on the scalp although on other body sites. Alopecia is characterized by round or oval patches of non scarring hair loss. Scalp hair loss can be partial or complete, but it progress to cause total body hair loss. Emulgel are emulsion gel which contains widely distributed oil droplets. Chemically, minoxidil is 2,4-pyrimidinediamine, 6-[1-piperidinyl]-,3-oxide. Minoxidil is antihypertensive drug; a powerful vasodialator which act by direct relaxation of arteriolar smooth muscle. An attempt was made to formulate minoxidil emulgel for the treatment

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Tayal, Shivam, Pradyumn Tiwari, Vinod Sahu, and Shivang Sharma. "Preparation and Characterization of an Antiviral Gel." International Journal of Pharma Professional’s Research (IJPPR) 14, no. 4 (2023): 150–56. http://dx.doi.org/10.48165/ijppronline.2023.14413.

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The study was to develop an antiviral gel for topical application. The topical application of drug has many advantages over the intravenous and oral administration. It prevents metabolism of drug from liver and avoid the risk of gastrointestinal disorder and inconvenience of intravenous therapy pain. When the drug is applied topically it can penetrate deeper into the skin hence show better absorption and bioavailability. The wide varieties of pharmaceutical dosage form are available for topical drug delivery system. The most used one is gel, ointment and cream. Herpes Simplex Virus (HSV) is wi

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Govind, Patidar* Praveen Khirwadkar Tanu Bhargav. "Incorporation Of Neomycin-Nicotinamide Microemulsion in Emulgel for Enhanced Antibacterial Skin Therapy." International Journal of Pharmaceutical Sciences 3, no. 2 (2025): 1145–68. https://doi.org/10.5281/zenodo.14874104.

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This study focused on the development and evaluation of Emulgel formulations containing Neomycin and Nicotinamide for potential use in antibacterial skin therapy. Three formulations, F1, F2, and F3, were prepared using Carbopol 940, Carbopol 934, and Hydroxypropyl Methylcellulose (HPMC) as the base polymers, respectively. The formulations were characterized for λmax using UV spectroscopy, which identified the optimal wavelengths for Neomycin (270 nm) and Nicotinamide (262 nm). Calibration curves were established to facilitate accurate quantitative analysis of these active pharmaceutical

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Muslim, Rana K., and Nidhal Maraie. "Perspective Impact of Gelling Agents on the Mechanistic Behavior for the Topical Delivery of Flufenamic Acid Nano-Ethosomal Dispersion." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 02 (2022): 789–97. http://dx.doi.org/10.25258/ijddt.12.2.57.

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Objective: This work involves the preparation and in vitro characterization of a topical gel formulation that is capable of deep skin permeation, providing the anti-inflammatory effect for the optimum nano ethosomal dispersion formula. Methods: The optimum ethosomal dispersion was prepared (in our laboratory) by utilizing 3% flufenamic acid (FA), 30% ethanol, 1% phosphatidylcholine (PC), 10% propylene glycol, and 1% cholesterol by cold method and 20 minutes’ ultra-sonication. Four ethosomal gel formulas (G1-G4) were prepared by using carbopol 934 and carbopol 940 at 1% and 1.5% concentration a

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Lestari, Pramulani Mulya, Kori Yati, and Nanda Savira. "Comparison of carbopol 934 and 941 as thickeners on ketoconazole microemulsions based on physical stability." Pharmaciana 8, no. 1 (2018): 119. http://dx.doi.org/10.12928/pharmaciana.v8i1.9138.

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Kusumaningrum, Aliffia Ayu, Nova Primadina, Afrita Amalia Laitupa, and Nenny Triastuti. "Literature Review: Pengaruh Pegagan terhadap Penyembuhan Luka Bakar." MAHESA : Malahayati Health Student Journal 3, no. 7 (2023): 2160–77. http://dx.doi.org/10.33024/mahesa.v3i7.10728.

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ABSTRACT Burns are injuries caused by the passage of energy from a heat source to the body's tissue under the skin. Each year, 265,000 people die from burns globally, according to WHO (2014). Both traditional and conventional medicine have been used to treat burns, but the price of conventional drugs is relatively high, resulting in inefficient use and side effects such as scar tissue formation, whereas traditional medicine is feared for infection and decreased drug effectiveness due to improper processing. The purpose of this Literature Review is to assess the effect of Centella asiatica on b

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Anum, Kamil, Humaira Naureen, Masood-Ur-Rehman, et al. "Development and characterization of ceftriaxone in-situ gel-forming biodegradable parenteral depot system." Tropical Journal of Pharmaceutical Research 20, no. 4 (2022): 673–80. http://dx.doi.org/10.4314/tjpr.v20i4.2.

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    Purpose: To design parenteral in-situ gel of ceftriaxone using poloxamer as a thermosensitive agent, Carbopol as a pH-sensitive polymer and hydroxypropyl methylcellulose as a viscosity enhancer. Method: Lyophilized ceftriaxone was added in solution form to enhance its solubility and stability. Several formulations were designed using poloxamer (P 188, F 127 and P 407) and Carbopol (934P and 940) in varying concentrations, out of which an optimized formulation was chosen on the basis of its gelling capacity and respective transit time. Drug content uniformity,

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Pathare, Sujit, Snehal Babar, Manoj Tare, et al. "Pharmacobotanical Application of Ricinus communis Seed Oil in Formulation and Evaluation of Herbal Emulgel for the Treatment of Psoriasis." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 13, no. 01 (2023): 279–84. http://dx.doi.org/10.25258/ijddt.13.1.45.

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Infl ammatory and immune-mediated skin disease, psoriasis. It’s common for psoriasis to be seen in people all over the globe. Drugs are most eff ectively delivered through the topical route for treating skin conditions. An attempt was made to increase the eff ectiveness of topical treatment for psoriasis by using emulgel compositions containing Ricinus communis seed oil. In order to create the gel, the extract was mixed with liquid paraffi n, olive and coconut oils, and Carbopol 936 and 940 gelling agents. The viscosity and glossiness of the emulgel were achieved using herbal extracts. When te

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FALAHI, ASA. "PENGARUH VARIASI KONSENTRASI CARBOPOL 934 SEBAGAI PENGENTAL TERHADAP SIFAT FISIK SEDIAAN SAMPO INFUSA DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.)." JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 5, no. 1 (2022): 24–30. http://dx.doi.org/10.53864/jifakfar.v5i1.104.

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The purpose of this study was to determine the effect of variation concentration carbopol 934 934 to the characteristics of physical shampoo from anti-dandruff infusion of pandan leaves (Pandanus amaryllifolius roxb). Pre-experiment one shot case study was used as a research design. Variation in carbopol 934 concentration were 1% (F1), 1.5% (F2), and 2% (F3) The result stowed that variation concentration of carbopol 934 affect organoleptic shape and smell, pH, and viscosity of shampoo. But didn’t affect color, homogenity, and foam height oh shampoo. The viscosity of the shampoo increases with

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FALAHI, ASA. "PENGARUH VARIASI KONSENTRASI CARBOPOL 934 SEBAGAI PENGENTAL TERHADAP SIFAT FISIK SEDIAAN SAMPO INFUSA DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.)." JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 5, no. 1 (2022): 24–30. http://dx.doi.org/10.53864/jifakfar.v5i1.114.

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The purpose of this study was to determine the effect of variation concentration carbopol 934 934 to the characteristics of physical shampoo from anti-dandruff infusion of pandan leaves (Pandanus amaryllifolius roxb). Pre-experiment one shot case study was used as a research design. Variation in carbopol 934 concentration were 1% (F1), 1.5% (F2), and 2% (F3) The result stowed that variation concentration of carbopol 934 affect organoleptic shape and smell, pH, and viscosity of shampoo. But didn’t affect color, homogenity, and foam height oh shampoo. The viscosity of the shampoo increases with

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Dawre, Shilpa, and Saloni Agarwal. "Development and Characterization of Adapalene Loaded Microemulsion-Based Hydrogel for Acne Treatment Adapalene Microemulsion." International Journal of Drug Delivery & Controlled Release 2, no. 1 (2023): 38–44. http://dx.doi.org/10.55124/jdcr.v2i1.233.

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Presently, acne is affecting globally many people (9.4%) and one of the leading causes of stress especially in youths. Adapalene (AD) has been applied successfully for acne treatment. However, adapalene drug is from BCS class II and exhibits less solubility in water (<1mg/mL) & causes skin irritation which leads to patient incompliance. The objective of the current study was design of microemulsion-based gel for topical delivery of adapalene. Solubility studies demonstrated that adapalene exhibit good solubility in Tween 80, propylene glycol, and oleic acid. The microemulsion showed glo

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Marlina, Dewi, Fadly Fadly, and Zafira Fathya. "FORMULATION AND EVALUATION OF ANTI-ACNE SPRAY GEL OF SECANG WOOD EXTRACT (Caesalpinia sappan L.) WITH VARIAOUS OF CONCENTRATION OF CARBOPOL 940 AS GELLING AGENT." JKPharm Jurnal Kesehatan Farmasi 3, no. 2 (2021): 132–38. http://dx.doi.org/10.36086/jkpharm.v3i2.899.

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Latar Belakang : Spray gel merupakan bentuk pengembangan sediaan gel. Salah satu komponen yang perlu diperhatikan dalam memfomulasikan sediaan spray gel adalah konsentrasi pembentuk gel yaitu carbopol 940 yang merupakan polimer pembe ntuk gel yang sering digunakan. Penelitian ini bertujuan untuk mengetahui konsentrasi carbopol 940 yang dapat menghasilkan spray gel yang stabil dan memenuhi persyaratan dengan zat aktif kayu secang (Caesalpinia sappan L.) yang berfungsi sebagai anti jerawat. Metode : Penelitian ini menggunakan metode eksperimental, dengan esktrak kayu secang (Caesalpinia sa

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Khatimah, Husnul, Siti Aisiyah, and Destik Wulandari. "Formulasi Dan Uji Aktivitas Antibakteri Sediaan Sabun Cair Ekstrak Bunga Cengkeh (Syzygium aromaticum L.) Dengan Variasi Konsentrasi Carbopol 940 Terhadap Bakteri Staphylococcus aureus ATCC 25923." Organisms: Journal of Biosciences 3, no. 1 (2023): 43–54. http://dx.doi.org/10.24042/organisms.v3i1.16609.

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Liquid soap is one of the preparations to prevent skin infections caused by bacteria. One of the bacteria that causes infection is Staphylococcus aureus. The content of flavonoids, tannins and alkaloids found in clove flowers (Syzygium aromaticum L.) can inhibit antibacterial activity. This study aims to determine the effect of varying concentrations of carbopol 940 on the physical quality of liquid soap preparations of clove flower extract, having antibacterial activity against Staphylococcus aureus bacteria and which formula has the best physical quality. The results showed that variations i

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Febrianti, Dwi Rizki, Eka Kumalasari, Rakhmadhan Niah, Novia Ariani, Supomo Supomo, and Dita Ayulia Dwi Sandi. "FORMULASI DAN EVALUASI GEL HAND SANITIZER DARI MINYAK ATSIRI BUNGA LILI (Lilium auratum)." Jurnal Pharmascience 11, no. 1 (2024): 78. http://dx.doi.org/10.20527/jps.v11i1.13822.

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Minyak atsiri bunga lili (lilium auratum) dapat berpotensi sebagai antibakteri dengan memformulasikan dalam bentuk sediaan gel hand sanitizer. Tujuan penelitian ini adalah untuk menentukan sediaan gel antiseptik (Hand sanitizer) minyak atsiri bunga lili dengan berbagai konsentrasi gelling agent carbopol 940 yang mempunyai sifat fisik yang baik dan memenuhi syarat. Carbopol 940 divariasikan dengan konsentrasi 0,667 % dan 1,334% dari total formula. Penelitian ini menggunakan metode eksperimental. Formula diuji sifat fisiknya, seperti uji organoleptis, pH, homogenitas, daya lekat dan daya sebar.

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Anggoro, Novita, and Nur Cholis Endriyatno. "Formulasi gel ekstrak daun sirih cina (Peperomia pellucida L. Kunth) variasi carbopol 940 serta uji fisik dan stabilitasnya." Sasambo Journal of Pharmacy 5, no. 1 (2024): 46–54. http://dx.doi.org/10.29303/sjp.v5i1.286.

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Chinese betel leaf (Peperomia pellucida L. Kunth) contains tannins, alkaloids, saponins and flavonoids which can inhibit the growth of Propionibacterium acnes bacteria. Gel preparations are suitable for topical therapy of acne. The gelling agent used was carbopol 940. The purpose of this study was to determine the effect and concentration of carbopol 940 which produced the best physical properties of Chinese betel leaf extract gel preparations. This research is an experimental research. Gel preparations were made with various concentrations of carbopol 940 0.5%, 1.0%, 1.5%, and 2.0% then organ

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Kumar, Manish. "Development and Evaluation of Transdermal Gel for Pain Relief." Frontiers in Scientific Research & Artificial Intelligence 1, no. 1 (2023): 1–6. http://dx.doi.org/10.31531/fsrai.1000102.

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The study was to develop transdermal gel formulations for the delivery of aspirin and paracetamol. Compared to more conventional approaches like oral, injectable, and inhaler administration, transdermal medication delivery through the skin has a number of benefits. These benefits include self-administering simplicity, non-intrusiveness, usability, cost, and the capacity to maintain sustained plasma drug concentrations over prolonged periods of time. Two polymers in creating transdermal gels Carbopol-934 and Sodium Alginate were assessed. Carbopol-934 was chosen because of its capacity to impro

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Iin Lidia Putama Mursal, Anggun Hari Kusumawati, and Devi Hartianti Puspasari. "PENGARUH VARIASI KONSENTRASI GELLING AGENT CARBOPOL 940 TERHADAP SIFAT FISIK SEDIAAN GEL HAND SANITIZER MINYAK ATSIRI DAUN KEMANGI (Ocimum Sanctum L.)." Pharma Xplore : Jurnal Ilmiah Farmasi 4, no. 1 (2019): 268–77. http://dx.doi.org/10.36805/farmasi.v4i1.617.

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ABSTRAK Hand sanitizer adalah produk efektif dan murah yang dapat mengurangi mikroorganisme pada kulit. Banyak hand sanitizer yang mengandung etanol dan alkohol dengan kadar 60% -95% tetapi kandungan alkohol dalam hand sanitizer dapat menyebabkan resiko kesehatan. Penelitian ini bertujuan untuk melihat pengaruh gelling agent Carbopol 940 terhadap sifat fisik sediaan gel hand sanitizer. Konsentrasi yang digunakan untuk gelling agent Carbopol 940 yaitu 0,5%; 1%; 1,5%. Uji sifat fisik meliputi uji organoleptik, uji homogenitas, uji pH, uji viskositas, uji daya sebar dan uji daya lekat. Hasi

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Sana, Nusrat Praween* Sallikim Sangma Tanya Sharma Pankaj Chasta. "Current Insights and Future Directions of Mesenchymal Stem Cell Therapy for Knee Osteoarthritis." International Journal of Pharmaceutical Sciences 2 (December 22, 2024): 2828–52. https://doi.org/10.5281/zenodo.14542927.

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Among the most recent developments in Skillful DDS, gel allows for the dual control of the emulsion's and gel's appearance, making it ideal for a variety of practical applications. Accuracy standards: An oil sorting device utilizing liquid paraffin and propylene glycol, a surfactant consisting of Tween 80 and arrive at 80, and the utilization of pseudo ternary coordinate graphs were utilized in the development of this smaller-than-common emulsion w/o. Using a variety of methods, the high-level emulsion orchestrate was mixed into the gel mixture containing Carbopol-934, HPMC-5, and HPMC15+ Carb

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M.Sudharshan, M. Sudharshan, Dr S. K. Senthil Kumar, M. Anandhi M.Anandhi, et al. "Formulation and Evaluation of Fenugreek Gel as a Topical AntiInflammatory Agent." International Journal of Pharmaceutical Research and Applications 10, no. 1 (2025): 1151–53. https://doi.org/10.35629/4494-100111511153.

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This study focused on the development and evaluation of a topical gel containing Trigonella foenumgreacum seed extract, formulated with carbopol-934 and HPMC K4M as gelling agents, to explore its anti-inflammatory potential. Gel formulations containing carbopol-934 and HPMC K4M were prepared, evaluated for their physicochemical properties, and subjected to in vitro permeation studies to determine the optimal formulation. The gel formulation prepared with a combination of carbopol-934 and HPMC K4M demonstrated the highest drug release rate, with 88.02±0.06% of the drug released after 8 hours in

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Widitasari, Ayunda Syifa, Endang Sri Rejeki, and Nur Aini Dewi Purnamasari. "PENGARUH VARIASI KONSENTRASI KARBOPOL 940 TERHADAP MUTU FISIK SEDIAAN EMULGEL EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) SEBAGAI TABIR SURYA SECARA In Vitro." EduNaturalia: Jurnal Biologi dan Kependidikan Biologi 4, no. 2 (2023): 41. http://dx.doi.org/10.26418/edunaturalia.v4i2.69346.

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Secondary metabolite like phenolic compounds found in kersen leaves have function to bind free radical. Emulgel is a preparation that is not greasy, spreads evenly, soft, and long lasting on storage. The objective of this study was to determine the physical quality of emulgel of kersen leave ethanol extract with various concentrations of carbopol 940, to determine the potential and effective concentration of carbopol 940 in emulgel of kersen leave ethanol extract as a sunscreen. This study used several formula with various concentration of carbopol 940 which is 1, 1.5, and 2%. Physical quality

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Rahmawati, Eka Diana, Weka Sidha Bhagawan, and Fidia Rizkiah. "OPTIMIZATION OF CARBOPOL 940 AND OLEIC ACID IN DICLOFENAC SODIUM BASE GEL USING FACTORIAL DESIGN 22 METHOD." Journal of Islamic Pharmacy 3, no. 1 (2018): 15. http://dx.doi.org/10.18860/jip.v3i1.4993.

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<em>The aim of the present study was to determine the effect of carbopol 940, oleic acid and interaction of both in the value of viscosity and release rate and to find optimum formula of diclofenac sodium base gel which can produced viscoisity between 20 dPa.s - 200 dPa.s and rate release 50μg/cm<sup>2</sup>.menit<sup>1/2</sup> - 150μg/cm<sup>2</sup>.menit<sup>1/2</sup> using factorial design 2<sup>2</sup>. The level of carbopol 940 were 1,3% and 0,8% while the level of oleic acid were 5% and 20%. Analysis of the research used D

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Chandra, M. Andi, Ilham Kuncahyo, and Ana Indrayati. "Optimization of Quercetin Gel Formulation using Factorial Design Method and Antibacterial Test against Propionibacterium acnes." Borneo Journal of Pharmacy 5, no. 2 (2022): 126–35. http://dx.doi.org/10.33084/bjop.v5i2.3321.

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Quercetin is a flavonoid from a group of polyphenolic flavonoid compounds. Quercetin can be used as an alternative to acne treatment, predominantly triggered by Propionibacterium acnes. This study aimed to determine the effect and proportion of carbopol 940, propylene glycol, and glycerin on the physical quality of quercetin gel, the ability of the optimum formula in an antibacterial test, and its diffusion using Franz diffusion. This study uses the factorial design method for formula optimization. Optimization was carried out with the parameters of the physical quality of the gel tested, incl

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Akshay Kumar, Shivam Mishra, Badal Kumar, Pankaj Sharma, and Ekta. "Formulation and characterization of Carbopol based caffeine hydrogel transdermal film." International Journal of Science and Research Archive 15, no. 1 (2025): 882–87. https://doi.org/10.30574/ijsra.2025.15.1.1086.

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A transdermal patch containing caffeine was developed using Carbopol-940 as the hydrogel matrix. Caffeine transdermal films were made utilizing the solvent casting method with the lipophilic PEG-1500 and hydrophilic carbopol-940. As a plasticizer, propylene glycol (PG) was employed. The drug content, thickness, tensile strength, folding durability, and in vitro drug release—which was investigated using Franz diffusion cells—were all assessed for these films. The purpose of the study was to publish physicochemical data, including in vitro drug release, and the film-forming capabilities of the p

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Abdul, Bari Mohd. "FORMULATION AND INVITRO EVALUATION OF ECONAZOLE NITRATE TOPICAL GEL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 08 (2018): 8136–44. https://doi.org/10.5281/zenodo.1407161.

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<em>In the present work an attempt was being made to formulate and evaluate Topical gel containing anti inflammatory drug Econazole nitrate. Carbopol 971, Guar gum and carbopol 934 were selected as polymers.The drug and excipient compatability was studied by using FTIR Nine formulations of gels were prepared by taking different quantities of polymers. The prepared gel was subjected to various evaluation tests like pH, spreadability, viscosity, content uniformity and diffusion studies conducted upto 12hrs.All the results were with in the limits , by diffusion studies it was observed that formul

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Goswami Swapan Shantiram. "Qualitative Evaluation of Carbopol-940 Gel Used as a Preservative Medium Compared to Traditional Modified Kaiserling III Solution in Pathology Museum." Journal of Advanced Zoology 44, no. 3 (2023): 1190–200. http://dx.doi.org/10.17762/jaz.v44i3.1228.

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Introduction: Body organs and tissue specimens have been preserved in human and veterinary anatomy, pathology museums for years in traditional modified Kaiserling III solution. Wax embedding, epoxy-resin embedding and Plastination techniques have also been tried. However, the use of Carbopol-940 gel as a preservative medium is not mentioned in the literature. Gel preservative medium can prevent leakage, toxic vapors, and irritation of eyes and skin. Aims: Qualitative evaluation of carbopol-940 gel as a preservative medium for specimens in pathology museums compared to modified Kaiserling III s

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Sari, Febriana Mukti Permata, Siti Aisiyah, and Destik Wulandari. "FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN SABUN CAIR EKSTRAK SABUT KELAPA (Cocos nucifera L. ) DENGAN VARIASI KONSENTRASI CARBOPOL 940 TERHADAP BAKTERI Staphylococcus aureus ATCC 25923." EduNaturalia: Jurnal Biologi dan Kependidikan Biologi 4, no. 1 (2023): 1. http://dx.doi.org/10.26418/edunaturalia.v4i1.61425.

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Shower gel is one of the preparations that can be used to protect the skin from Staphylococcus aureus bacterial infection. Plants that have antibacterial activity are coconut husk, the compounds contained are tannins, flavonoids, and polyphenols. Tannins have the activity of inhibiting the growth of Staphylococcus aureus bacteria. This study aims to determine the influence of Carbopol 940 variations on liquid soap preparations. Liquid soap preparations have antibacterial activity, find out which formulas have the best physical quality. Coconut husk extract was obtained by maceration method usi

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Montella, Clara, Noval Noval, and Darini Kurniawati. "Formulasi dan Evaluasi Nano Spray Gel Ekstrak Buah Karamunting (Rhodomyrtus tomentosa (Aiton) Hassk.) dengan Variasi Konsentrasi Carbopol 940." Jurnal Surya Medika 10, no. 2 (2024): 117–28. http://dx.doi.org/10.33084/jsm.v10i2.7733.

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Masalah kulit bisa terjadi akibat radikal bebas maka diperlukan antioksidan yang bisa dimanfaatkan dari bahan alam yang memiliki potensi walaupun jarang diketahui atau digunakan seperti buah karamunting (Rhodomyrtus tomentosa (Aiton) Hassk.). Perlu dilakukan evaluasi formulasi sediaan nano spray gel ekstrak buah dari tanaman karamunting (Rhodomyrtus tomentosa (Aiton) Hassk.) dengan variasi konsentrasi basis carbopol 940 untuk mengetahui pengaruh variasi basis carbopol 940 pada sediaan nano spray gel ekstrak buah tanaman karamunting (Rhodomyrtus tomentosa (Aiton) Hassk.), sehingga digunakanlah

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Anita Nilawati, Ayu Bainunniza, and Reslely Harjanti. "FORMULASI SERUM ANTIOKSIDAN EKSTRAK ETANOL DAUN MATOA (POMETIA PINNATA J.R FORST AND G. FORST) DENGAN VARIASI GELLING AGENT CARBOPOL 940." Intan Husada : Jurnal Ilmiah Keperawatan 12, no. 02 (2024): 258–70. http://dx.doi.org/10.52236/ih.v12i2.608.

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Daun matoa (Pometia pinnata J.R Forst and G. Forst) mengandung flavonoid yang berpotensi sebagai antioksidan alami. Senyawa yang berasal dari bahan alam, terutama flavonoid banyak dimanfaatkan salah satunya sebagai komponen aktif dalam sediaan kosmetik. Serum adalah salah satu jenis sediaan kosmetik dengan konsentrasi kandungan zat aktif tinggi dan viskositas rendah, yang mampu menghantarkan film tipis dari bahan aktif pada permukaan kulit. Carbopol 940 digunakan sebagai gelling agent yang dapat mempengaruhi nilai viskositas dan daya sebar pada sediaan. Tujuan. Penelitian ini bertujuan untuk m

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Verma, Ribha, Ramakant Lamichhane, and Joshna Shrestha. "Formulation & In Vitro Evaluation of Effect of Polymer in Gastro-Retentive Drug Delivery System Using Ciprofloxacin Hydrochloride as A Model Drug." Dinkum Journal of Medical Innovations 3, no. 03 (2024): 271–89. https://doi.org/10.71017/djmi.3.3.d-0268.

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Gastro-retentive dosage form offer many advantages having absorption from upper gastrointestinal tract and improve the bioavailability of medications that are characterized by a narrow absorption window. A new gastro-retentive floating drug delivery system was developed for ciprofloxacin preferably once daily. The design of the delivery system was based on the sustained release formulation with floating and swelling features in order to prolong the gastric retention time of the drug delivery system. Final formulations were prepared and optimized by Box-Behnken design by using HPMC K100M and Ca

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Parmar, Nilesh, Ramakant Sharma, Jeevan Patel, Shabnam Khan, and Rakesh Patel. "FORMULATION AND EVALUATION STUDIES OF VALACYCLOVIR TOPICAL GEL FOR ANTIVIRAL ACTIVITY." International Journal of Pharmaceutical Sciences and Medicine 7, no. 10 (2022): 97–118. http://dx.doi.org/10.47760/ijpsm.2022.v07i10.006.

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The present work describes a study on Formulation and Evaluation studies of Valacyclovir topical gels for Antiviral activity. Valacyclovir is a broad spectrum antiviral agent against Herpes Simplex Virus and Varicella Zoster Virus, which is specific to viral-infected cells with low toxicity and which is less toxic than earlier generation of antiviral agents and as such represents a major therapeutic advance. This drug was selected for the study because it has good percutaneous absorption and appears to be more active as antiviral activity and is well tolerated. The polymers namely Carbopol-934

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Suzalin, Ferawati, Dewi Marlina, and Selvi Agustini. "Formulasi dan Evaluasi Gel Antijerawat Ekstrak Daun Jeringau Hijau (Acorus Calamus L.) Dengan Variasi Konsentrasi Carbopol 940 Sebagai Gelling Agent." JKPharm Jurnal Kesehatan Farmasi 3, no. 1 (2021): 7–16. http://dx.doi.org/10.36086/jpharm.v3i1.901.

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Latar Belakang: Gel merupakan salah satu bentuk sediaan yang bisa digunakan untuk mengobati jerawat.Basis gel yang biasa digunakan adalah carbopol 940 karena dengan konsentrasi kecil yaitu 0,5%-2% dapat menghasilkan gel yang jernih dengan viskositastinggi. Penelitian ini bertujuan untuk mengetahui konsentrasi carbopol 940 yang optimal untuk menghasilkan gel yang stabil dan memenuhi persyaratan. Gel yang dibuat menggunakan zat aktif daun jeringau hijau (Acorus calamus L.) dengan kandungan senyawa aktif flavonoid dan saponin Metode: Penelitian ini menggunakan metode eksperimental, dengan e

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Astriani, Andi Dian, Ana Fitriani, and Ermina Pakki. "Formulasi dan Uji Stabilitas Fisik Sediaan Gel Ekstrak Etanol Daun Rambutan (Nephelium Lappaceum L.)." Journal of Pharmaceutical and Health Research 4, no. 3 (2023): 421–26. http://dx.doi.org/10.47065/jharma.v4i3.3412.

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The ethanol extract of rambutan leaves has anti-Staphylococcus aureus properties. The purpose of this investigation is to formulate the ethanol extract of rambutan leaves (Nephelium lappaceum L.) in order to determine the stable concentration of carbopol 940 for gel preparations. The extraction technique utilised was maceration with 96% ethanol. Formula 1 (0.7% carbopol 940), Formula 2 (0.9% carbopol 940), and Formula 3 (1.1% carbopol 940) were developed for the gel preparation formulation. Organoleptic assays, homogeneity, spreadability, pH, and adhesion were conducted before and after accele

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Kawkab, Mohammed and Abdul Bari Mohd. "FORMULATION AND INVITRO EVALUATION OF TAZAROTENE TOPICAL GEL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 02 (2019): 4003–12. https://doi.org/10.5281/zenodo.2565304.

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<em>Tazarotene is a member of the acetylenic class of retinoids. This medication is approved for treatment of psoriasis, acne, and sun damaged skin .In the present work an attempt was being made to formulate and evaluate topical gel containing antipsoriatics drug </em><em>Tazarotene</em><em>. Carbopol 971, </em><em>Sodium CMC </em><em>and carbopol 934 were selected as polymers.The drug and excipient compatability was studied by using FTIR Nine formulations of gels were prepared by taking different quantities of polymers</em><em> .</em><em>The prepared gel was subjected to variou

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Kasmayuda, Muhammad, Mia Audina, Dede Mahdiyah, and Noval Noval. "Pengaruh Konsentrasi Carbopol 940 dan Paraffin Liquid terhadap Evaluasi Sediaan Serum Emulgel Ekstrak Pegagan (Centella asiatica (L.) Urban) Sebagai Anti Jerawat." Journal Pharmaceutical Care and Sciences 5, no. 1 (2024): 101–12. https://doi.org/10.33859/jpcs.v5i1.663.

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Latar Belakang: Jerawat merupakan salah satu masalah kesehatan pada kulit yang sering dialami setiap orang. Jerawat atau acne merupakan salah satu penyakit kulit yang umum terjadi diberbagai usia mulai dari remaja hingga dewasa. Pegagan (Centella asiatica (L.) Urban) merupakan tumbuhan yang memiliki khasiat sebagai antibakteri untuk mengatasi bakteri penyebab jerawat. Serum emulgel adalah sediaan liquid yang memiliki bahan aktif berkonsentrasi tinggi dengan basis kombinasi antara emulsi dan gel.Tujuan: Mengidentifikasi formulasi variasi konsentrasi carbopol 940 dan paraffin liquid berdasarkan

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G. Munshi, Azima, Manish Goyani, and Meghraj V. Suryawanshi. "FORMULATION AND DEVELOPMENT OF LONG-ACTING THERMOSENSITIVE AND MUCOADHESIVE VAGINAL GEL OF METRONIDAZOLE." Indian Drugs 60, no. 06 (2023): 34–41. http://dx.doi.org/10.53879/id.60.06.13069.

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The development of an in situ metronidazole gel that is mucoadhesive and thermo sensitive was the aim of this study in the fight against bacterial vaginosis. Numerous evaluation criteria have been carried out, including mucoadhesive force, pH, viscosity, syringe capability, medication content, gelation temperature, and gelation time. All of the solutions were found to have pH values between 6-7. The viscosity was correlated with the mucoadhesive force. The drug release parameter indicates that in situ gels containing Carbopol 934 provide superior drug release compared to other polymers. Additi

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