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Journal articles on the topic 'Carbopol 934'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

FALAHI, ASA. "PENGARUH VARIASI KONSENTRASI CARBOPOL 934 SEBAGAI PENGENTAL TERHADAP SIFAT FISIK SEDIAAN SAMPO INFUSA DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.)." JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 5, no. 1 (2022): 24–30. http://dx.doi.org/10.53864/jifakfar.v5i1.104.

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The purpose of this study was to determine the effect of variation concentration carbopol 934 934 to the characteristics of physical shampoo from anti-dandruff infusion of pandan leaves (Pandanus amaryllifolius roxb). Pre-experiment one shot case study was used as a research design. Variation in carbopol 934 concentration were 1% (F1), 1.5% (F2), and 2% (F3) The result stowed that variation concentration of carbopol 934 affect organoleptic shape and smell, pH, and viscosity of shampoo. But didn’t affect color, homogenity, and foam height oh shampoo. The viscosity of the shampoo increases with

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FALAHI, ASA. "PENGARUH VARIASI KONSENTRASI CARBOPOL 934 SEBAGAI PENGENTAL TERHADAP SIFAT FISIK SEDIAAN SAMPO INFUSA DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.)." JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 5, no. 1 (2022): 24–30. http://dx.doi.org/10.53864/jifakfar.v5i1.114.

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The purpose of this study was to determine the effect of variation concentration carbopol 934 934 to the characteristics of physical shampoo from anti-dandruff infusion of pandan leaves (Pandanus amaryllifolius roxb). Pre-experiment one shot case study was used as a research design. Variation in carbopol 934 concentration were 1% (F1), 1.5% (F2), and 2% (F3) The result stowed that variation concentration of carbopol 934 affect organoleptic shape and smell, pH, and viscosity of shampoo. But didn’t affect color, homogenity, and foam height oh shampoo. The viscosity of the shampoo increases with

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Anchal Dwivedi, Shriyanshi Singh Rana, Vishal Dubey, Megha Tiwari, Mayur Porwal, and Anita Devi. "Formulation and Evaluation of ACNE Gel using Metronidazole and Doxycycline." Journal of Advanced Zoology 44, S6 (2023): 72–79. http://dx.doi.org/10.17762/jaz.v44is6.1986.

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This research study focuses on the formulation and evaluation of an ACNE gel using Metronidazole (1%) and Doxycycline (0.5%) as active ingredients. Three types of polymers, Hydroxypropyl Methylcellulose (HPMC), Carbopol 940, and Carbopol 934 were used for gel formation. The formulated gels were evaluated for their physical characteristics, in vitro drug release, and drug-polymer compatibility. The calibration curves for both Metronidazole and Doxycycline displayed strong linearity within the concentration range of 5 to 25 µg/mL, facilitating accurate drug quantification. The gel formulations e

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Kumar, Manish. "Development and Evaluation of Transdermal Gel for Pain Relief." Frontiers in Scientific Research & Artificial Intelligence 1, no. 1 (2023): 1–6. http://dx.doi.org/10.31531/fsrai.1000102.

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The study was to develop transdermal gel formulations for the delivery of aspirin and paracetamol. Compared to more conventional approaches like oral, injectable, and inhaler administration, transdermal medication delivery through the skin has a number of benefits. These benefits include self-administering simplicity, non-intrusiveness, usability, cost, and the capacity to maintain sustained plasma drug concentrations over prolonged periods of time. Two polymers in creating transdermal gels Carbopol-934 and Sodium Alginate were assessed. Carbopol-934 was chosen because of its capacity to impro

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Sana, Nusrat Praween* Sallikim Sangma Tanya Sharma Pankaj Chasta. "Current Insights and Future Directions of Mesenchymal Stem Cell Therapy for Knee Osteoarthritis." International Journal of Pharmaceutical Sciences 2 (December 22, 2024): 2828–52. https://doi.org/10.5281/zenodo.14542927.

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Among the most recent developments in Skillful DDS, gel allows for the dual control of the emulsion's and gel's appearance, making it ideal for a variety of practical applications. Accuracy standards: An oil sorting device utilizing liquid paraffin and propylene glycol, a surfactant consisting of Tween 80 and arrive at 80, and the utilization of pseudo ternary coordinate graphs were utilized in the development of this smaller-than-common emulsion w/o. Using a variety of methods, the high-level emulsion orchestrate was mixed into the gel mixture containing Carbopol-934, HPMC-5, and HPMC15+ Carb

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M.Sudharshan, M. Sudharshan, Dr S. K. Senthil Kumar, M. Anandhi M.Anandhi, et al. "Formulation and Evaluation of Fenugreek Gel as a Topical AntiInflammatory Agent." International Journal of Pharmaceutical Research and Applications 10, no. 1 (2025): 1151–53. https://doi.org/10.35629/4494-100111511153.

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This study focused on the development and evaluation of a topical gel containing Trigonella foenumgreacum seed extract, formulated with carbopol-934 and HPMC K4M as gelling agents, to explore its anti-inflammatory potential. Gel formulations containing carbopol-934 and HPMC K4M were prepared, evaluated for their physicochemical properties, and subjected to in vitro permeation studies to determine the optimal formulation. The gel formulation prepared with a combination of carbopol-934 and HPMC K4M demonstrated the highest drug release rate, with 88.02±0.06% of the drug released after 8 hours in

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Abdul, Bari Mohd. "FORMULATION AND INVITRO EVALUATION OF ECONAZOLE NITRATE TOPICAL GEL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 08 (2018): 8136–44. https://doi.org/10.5281/zenodo.1407161.

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<em>In the present work an attempt was being made to formulate and evaluate Topical gel containing anti inflammatory drug Econazole nitrate. Carbopol 971, Guar gum and carbopol 934 were selected as polymers.The drug and excipient compatability was studied by using FTIR Nine formulations of gels were prepared by taking different quantities of polymers. The prepared gel was subjected to various evaluation tests like pH, spreadability, viscosity, content uniformity and diffusion studies conducted upto 12hrs.All the results were with in the limits , by diffusion studies it was observed that formul

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Verma, Ribha, Ramakant Lamichhane, and Joshna Shrestha. "Formulation & In Vitro Evaluation of Effect of Polymer in Gastro-Retentive Drug Delivery System Using Ciprofloxacin Hydrochloride as A Model Drug." Dinkum Journal of Medical Innovations 3, no. 03 (2024): 271–89. https://doi.org/10.71017/djmi.3.3.d-0268.

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Gastro-retentive dosage form offer many advantages having absorption from upper gastrointestinal tract and improve the bioavailability of medications that are characterized by a narrow absorption window. A new gastro-retentive floating drug delivery system was developed for ciprofloxacin preferably once daily. The design of the delivery system was based on the sustained release formulation with floating and swelling features in order to prolong the gastric retention time of the drug delivery system. Final formulations were prepared and optimized by Box-Behnken design by using HPMC K100M and Ca

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Amalia, Anisa, Fith Khaira Nursal, Nining Nining, Tahyatul Bariroh, Andra Yunita Laszairina, and Adelia Dinaianti. "Formulasi Sabun Gel Ekstrak Biji Manjakani Menggunakan Tragakan dan Carbopol 934 sebagai Gelling Agent." Indonesian Journal of Pharmaceutical Science and Technology 11, no. 1 (2024): 101–8. http://dx.doi.org/10.24198/ijpst.v11i1.45499.

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Biji manjakani (Quercus infectoria) dapat digunakan sebagai bahan aktif pada sediaan sabun pembersih kewanitaan karena mengandung senyawa tannin yang dapat menghambat pertumbuhan jamur Candida albicans. Tragakan dan carbopol 934 merupakan gelling agent yang dapat digunakan pada pembuatan sabun gel. Tujuan penelitian ini adalah untuk mengetahui pengaruh perbedaan jenis dan konsentrasi gelling agent terhadap stabilitas fisik sabun gel pembersih kewanitaan ekstrak etanol 96% biji manjakani. Formula 1 - 4 menggunakan tragakan pada konsentrasi 0,5% (F1), 1% (F2), 1,5% (F3), dan 2% (F4). Formula 5 -

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G. Munshi, Azima, Manish Goyani, and Meghraj V. Suryawanshi. "FORMULATION AND DEVELOPMENT OF LONG-ACTING THERMOSENSITIVE AND MUCOADHESIVE VAGINAL GEL OF METRONIDAZOLE." Indian Drugs 60, no. 06 (2023): 34–41. http://dx.doi.org/10.53879/id.60.06.13069.

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The development of an in situ metronidazole gel that is mucoadhesive and thermo sensitive was the aim of this study in the fight against bacterial vaginosis. Numerous evaluation criteria have been carried out, including mucoadhesive force, pH, viscosity, syringe capability, medication content, gelation temperature, and gelation time. All of the solutions were found to have pH values between 6-7. The viscosity was correlated with the mucoadhesive force. The drug release parameter indicates that in situ gels containing Carbopol 934 provide superior drug release compared to other polymers. Additi

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Parmar, Nilesh, Ramakant Sharma, Jeevan Patel, Shabnam Khan, and Rakesh Patel. "FORMULATION AND EVALUATION STUDIES OF VALACYCLOVIR TOPICAL GEL FOR ANTIVIRAL ACTIVITY." International Journal of Pharmaceutical Sciences and Medicine 7, no. 10 (2022): 97–118. http://dx.doi.org/10.47760/ijpsm.2022.v07i10.006.

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The present work describes a study on Formulation and Evaluation studies of Valacyclovir topical gels for Antiviral activity. Valacyclovir is a broad spectrum antiviral agent against Herpes Simplex Virus and Varicella Zoster Virus, which is specific to viral-infected cells with low toxicity and which is less toxic than earlier generation of antiviral agents and as such represents a major therapeutic advance. This drug was selected for the study because it has good percutaneous absorption and appears to be more active as antiviral activity and is well tolerated. The polymers namely Carbopol-934

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L., Lahari *. E. Hima bindu Dr. Sowjanya battu Dr. Abbulu. "FORMULATION, DEVELOPMENT AND EVALUATION OF ANTI-DIABETIC ORAL INSITU GEL." Journal of Pharma Research 8, no. 8 (2019): 572–83. https://doi.org/10.5281/zenodo.3374091.

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<strong><em>ABSTRACT</em></strong> <strong><em>T</em></strong><em>he present research was focused to develop the formulation to release the drug Repaglinide for an extended period of time, thus prolong the residence time of formulation in the intestine. The in-situ gel formulations were developed to improve patient compliance. HPMC 50 cps, Carbopol 934 is used as polymers. Based on the concentration of polymer, the drug release was varied. Totally 12 formulations were prepared with HPMC 50cps and Carbopol 934P in various combinations. An in-vitro evaluation study was conducted in Franz diffusi

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Arora, Shivani, Khusi Chouksey, Trapti Shrivastava, and Kuldeep Ganju. "Formulation and Characterization of Intranasal Mucoadhesive Gel of Antiallergic Drug Loratadine for Improved Bioavailability." Journal of Drug Delivery and Therapeutics 15, no. 1 (2025): 67–72. https://doi.org/10.22270/jddt.v15i1.6952.

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The present study aimed to formulate and characterize an intranasal mucoadhesive gel of loratadine to enhance its bioavailability. Loratadine, an antihistamine, is commonly used for the treatment of allergic conditions, but its low bioavailability due to extensive first-pass metabolism can limit its effectiveness. To address this issue, an in situ gel formulation was developed using Poloxamer 407 and Carbopol 934 as excipients. The gel's physicochemical properties, including pH, drug content, viscosity, gel strength, gelation temperature, and drug release profile, were evaluated. FT-IR analysi

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Kawkab, Mohammed and Abdul Bari Mohd. "FORMULATION AND INVITRO EVALUATION OF TAZAROTENE TOPICAL GEL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 02 (2019): 4003–12. https://doi.org/10.5281/zenodo.2565304.

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<em>Tazarotene is a member of the acetylenic class of retinoids. This medication is approved for treatment of psoriasis, acne, and sun damaged skin .In the present work an attempt was being made to formulate and evaluate topical gel containing antipsoriatics drug </em><em>Tazarotene</em><em>. Carbopol 971, </em><em>Sodium CMC </em><em>and carbopol 934 were selected as polymers.The drug and excipient compatability was studied by using FTIR Nine formulations of gels were prepared by taking different quantities of polymers</em><em> .</em><em>The prepared gel was subjected to variou

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Saiyed, Selim Ali* Pintu Kumar De Himangshu Maji. "Development and Assessment of Aceclofenac Gel-Based Topical Formula." International Journal of Scientific Research and Technology 2, no. 2 (2025): 115–24. https://doi.org/10.5281/zenodo.14873940.

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Emulgel is an advanced drug delivery system that combines emulsion and gel for controlled topical release. Incorporating emulsion into a gel base enhances stability. Aceclofenac, a non-steroidal anti-inflammatory drug, is widely used for rheumatoid arthritis and osteoarthritis. This study aimed to develop and assess an aceclofenac emulgel to improve skin penetration compared to existing formulations. Five gelling agents—Carbopol 934, HPMC, Na CMC, and sodium alginate—were used. Drug release was tested via dialysis membrane, with all formulations exhibiting good physical properties.

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Genç, Lütfi, and A. Kıran. "In Vitro Evaluation of Sustained Released Matrix Tablet Formulations of Clarithromvcin." Scientia Pharmaceutica 73, no. 1 (2005): 59–74. http://dx.doi.org/10.3797/scipharm.aut-05-05.

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Sustained release matrix tablets of clarithromycin were prepared using different polymers as Hydroxypropyl methylcellulose (H PMC), Carbopol 934 and Eudragit RL/PO by direct compression technique. For the quality control of these formulations, weight deviation, hardness, friability, diameter-height ratio, content uniformity of the active substance and in vitro dissolution technique were performed. HPLC was used for the assay of clarithromycin and the assay method was validated. Dissolution profiles of the tablets were plotted and evaluated kinetically. The effects on drug release of polymer ty

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Shalviri, Alireza, Avinash C. Sharma, Dipak Patel, and Amyn Sayani. "Low-Surfactant Microemulsions for Enhanced Topical Delivery of Poorly Soluble Drugs." Journal of Pharmacy & Pharmaceutical Sciences 14, no. 3 (2011): 315. http://dx.doi.org/10.18433/j38p4v.

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Purpose: To develop and characterize low-surfactant microemulsion (ME) gels to enhance topical delivery of poorly soluble drugs. Method: Five low surfactant ME formulations were manufactured following the construction of pseudo-ternary phase diagrams. The MEs were screened for their ability to dissolve a poorly soluble new chemical entity (Model Drug X). Various viscosity imparting agents like Carbopol 934, Colloidal Silica, HPMC K100M, Lubrajel NP, and Xanthan Gum were evaluated for the manufacture of these ME gels. Each ME gel was then further evaluated for physical stability, including asse

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Wahyuni, Indah Suasani, Irna Sufiawati, Amira Shafuria, Wipawee Nittayananta, and Jutti Levita. "Formulation and Evaluation of Mucoadhesive Oral Care Gel Containing Kaempferia galanga Extract." Pharmaceutics 16, no. 3 (2024): 421. http://dx.doi.org/10.3390/pharmaceutics16030421.

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The rhizome of Kaempferia galanga (Zingiberaceae) is extensively used in traditional medicine by utilizing its various biological activities. It has been proven that ethyl-para-methoxycinnamate (EPMC) and other polyphenolic compounds are present in considerable amounts in the ethanolic extract of K. galanga rhizome (EKG). Our previous study confirmed that a dose of 0.5–1% of EKG demonstrated anti-inflammatory activity and a wound-healing effect in chemical-induced oral mucosal ulcers of Wistar rats. Currently, there are no reports on the formulation of oral gel containing EKG, thus revealing t

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Garge, Lajri, and Ravindranath B. Saudagar. "Development and Characterization of In Situ Ophthalmic Gel of Bepotastine Besilate." Journal of Drug Delivery and Therapeutics 9, no. 4-A (2019): 656–63. http://dx.doi.org/10.22270/jddt.v9i4-a.3547.

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The aim of the present work was development and characterization of in-situ Ophthalmic Gel of Bepotastine Besilate to overcome the drawbacks obtained by conventional eye drop. There are two independent variables were used i.e. Carbopol 934 and HPMC K100. Carbopol 934 were used as gelling agent and HPMC K100 were used as bioadhesive polymer. The in situ gelling system involves sol-to-gel transition in the cul-de-sac upon instillation to avoid pre corneal elimination. The formulations were prepared by 32 factorial design. The prepared formulations were evaluated for Clarity, pH, Viscosity, Bioad

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Pathan, Irfan Mustafa, Vishal S. Madankar, and Anil B. Panchal. "Formulation and Evaluation of Guava Leaf-Based Nanogel for Mouth Ulcer Treatment." Journal of Drug Delivery and Therapeutics 15, no. 4 (2025): 13–19. https://doi.org/10.22270/jddt.v15i4.7069.

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Mouth ulcers, also known as aphthous ulcers, are painful lesions affecting the oral mucosa, causing discomfort and irritation. Conventional treatments, such as antiseptic gels and corticosteroids, provide temporary relief but may have side effects with prolonged use. Guava leaves (Psidium guajava) contain bioactive compounds such as flavonoids, tannins, and polyphenols, which exhibit antimicrobial, anti-inflammatory, and wound-healing properties. This study focuses on the formulation of a simple, Nanogel using Carbopol 934 as a base for the treatment of mouth ulcers. The gel was prepared by in

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Pakhale, Nilesh V., S. B. Gondkar, and R. B. Saudagar. "Formulation Development and Evalua Tion of Fluoxetine Effervescent Floating Tablet." Journal of Drug Delivery and Therapeutics 9, no. 4-A (2019): 358–66. http://dx.doi.org/10.22270/jddt.v9i4-a.3490.

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The objective of the present study was to formulate and evaluate Effervescent Floating Tablet of Fluoxetine for the treatment of antidepressant agent. Tablets were prepared by direct compression using directly compressible polymers such as HPMC K4M, and Carbopol 934 were evaluated for drug-excipient compatibility, density, buoyancy test, swelling study, drug content and In-Vitro release profile. Sodium bicarbonate and citric acid were used producing effervescent base for buoyancy of tablets. Analysis of drug release from tablet indicates drug release by zero order, first order rate kinetics. N

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Sulaiman, Halah Talal, Saba Abdulhadi Jabir, and Khalid Kadhem Al-kinani. "INVESTIGATING THE EFFECT OF DIFFERENT GRADES AND CONCENTRATIONS OF PH‑SENSITIVE POLYMER ON PREPARATION AND CHARACTERIZATION OF LIDOCAINE HYDROCHLORIDE AS IN SITU GEL BUCCAL SPRAY." Asian Journal of Pharmaceutical and Clinical Research 11, no. 11 (2018): 401. http://dx.doi.org/10.22159/ajpcr.2018.v11i11.28492.

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Objective: The present study was aimed to develop a pH-triggered in situ gel for local release of lidocaine hydrochloride (lidocaine HCL) in the buccal cavity to improve the anesthetic effect of this amino amide drug which has very high water solubility. The formulations were introduced to the oral cavity as a spray to improve compliance and for easier administration.Methods: In this work, two grades of carbopol (934 and 940)-based in situ gel spray were designed. The formulations containing lidocaine HCl 5% were prepared by mixing different concentrations of carbopol with xanthan gum. Eight f

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Sonali, Verma1* Sandhya2. "Formulation And Development And In Vitro Evaluation Of Ocimum Sanctum Leave Microemulgel For Antioxidant Activity." International Journal in Pharmaceutical Sciences 2, no. 9 (2024): 27–38. https://doi.org/10.5281/zenodo.13871143.

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This study aimed to formulate and evaluate Microemulgel loaded with Ocimum sanctum leaf extract for antioxidant activity. Leaves were extracted using methanol, ethanol, and water, with ethanol providing the highest yield. The phytochemical analysis demonstrated the presence of bioactive compounds like alkaloids, flavonoids, terpenoids, and steroids in the extracts. Three formulations of Microemulgel were developed using different polymers - Carbopol 934, Carbopol 940, and HPMC. The formulated Microemulgel exhibited desirable properties including slightly acidic pH, high viscosity, and good spr

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Pranay, Sawant* Tejas Sutar Sayali Sawant Susmita Holmukhe. "Design and Assessment of Mucoadhesive Insitu Gel Forming Spray for Oral Delivery of Ibuprofen." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 3263–76. https://doi.org/10.5281/zenodo.15288007.

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The present study was aimed to develop an insitu gel forming spray for local release of Ibuprofen in the buccal cavity to improve the analgesic effect of NSAID drug which has poor water solubility. The formulations were introduced to the oral cavity as a spray to improve compliance and for easier administration. In this work, two grades of Carbopol (934 and 940)-based in situ gel spray were designed. The formulations containing Ibuprofen spray prepared by mixing different concentrations of Carbopol with xanthan gum. Four formulations were investigated and evaluated for pH, gelation capacity, s

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Begum, M. Yasmin, Ali Alqahtani, Mohammed Ghazwani, et al. "Preparation of Carbopol 934 Based Ketorolac Tromethamine Buccal Mucoadhesive Film: In Vitro, Ex Vivo, and In Vivo Assessments." International Journal of Polymer Science 2021 (October 11, 2021): 1–11. http://dx.doi.org/10.1155/2021/4786488.

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The goal of present investigation was to formulate and evaluate ketorolac tromethamine (KTM) mucoadhesive buccal films. The films were prepared by solvent evaporation method using PVP K30, HPMC K4M, HPMC K15M, carbopol 934, chitosan, and sodium alginate as polymers and propylene glycol as plasticizer. The films were evaluated for thickness, weight variation, folding endurance, surface pH, swelling index, in vitro residence time, in vitro diffusion, release kinetics, ex vivo permeation, in vitro-ex vivo correlation, and in vivo pharmacological activities such as anti-inflammatory and analgesic

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Sahoo, Subhashree, ChandraKanti Chakraborti, and SubashChandra Mishra. "Qualitative analysis of controlled release ciprofloxacin/carbopol 934 mucoadhesive suspension." Journal of Advanced Pharmaceutical Technology & Research 2, no. 3 (2011): 195. http://dx.doi.org/10.4103/2231-4040.85541.

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Vila-Jato, JoséL, Angel Concheiro, Begoña Seijo, and Begoña Viana. "Aging of nitrofurantoin tablets containing Carbopol 934 as a binder." International Journal of Pharmaceutics 30, no. 2-3 (1986): 229–36. http://dx.doi.org/10.1016/0378-5173(86)90084-0.

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Gómez-Carracedo, A., C. Alvarez-Lorenzo, J. L. Gómez-Amoza, R. Martínez-Pacheco, C. Souto, and A. Concheiro. "Extrusion-Spheronization of Blends of Carbopol 934 and Microcrystalline Cellulose." Drug Development and Industrial Pharmacy 27, no. 5 (2001): 381–91. http://dx.doi.org/10.1081/ddc-100104313.

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Dhananjay, Patil* Abdurrahman Helal Ahmed Mohammed Awais Sanaurrahman Rajashri More Karishma Shrivastav Rupesh Deore Vinod Bairagi. "FORMULATION, DEVELOPMENT AND IN VITRO EVALUATION OF SILDENAFIL CITRATE LIGNOCAINE HCl GEL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 08 (2018): 7921–37. https://doi.org/10.5281/zenodo.1403219.

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<em>The present study was undertaken to formulate, development and in vitro evaluation</em> <em>of Sildenafil Lignocaine gel</em>. <em>Sildenafil citrate is a drug of choice used in the treatment of premature ejaculation disorder</em>. <em>Topical gel has gained more and more importance because the gel based formulations are better percutaneously absorbed than creams and ointment bases</em>. <em>Therefore, topical gel of Sildenafil citrate was prepared using polymer of Carbopol 934 and triethanolamine at different proportions</em>. <em>The study encompasses compatibility studies using FTIR spe

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Ranganathan, Sundhararajan, Rajalakshmi Gopalakrishnan, RESHMA Chittettu Shajimon, et al. "Formulation and Evaluation of Cosmetic Gel Using Maranta Arundinacea L." Journal of Drug Delivery and Therapeutics 13, no. 5 (2023): 60–65. http://dx.doi.org/10.22270/jddt.v13i5.6068.

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In this study an attempt was made to formulate cosmetic gel using Maranta arundinacea (arrowroot powder) Arrowroot contains flavonoids which is known for its anti-inflammatory properties, antibacterial properties from long time. It has earned a reputation as an elegant, lightweight, all-natural absorbent powder with added skin-nourishing, reduce oiliness, anti-inflammatory properties, anti-irritant properties and for treating wounds from historical times. The rhizome of the plant was processed to obtain arrowroot powder. The cosmetic gel was developed using two polymers carbopol 934 and sodium

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Megha, Patel* Vishal Chudasama Kiran Suthar Bharat Rajpurohit. "Formulation and Evaluation of Polyherbal Gel." International Journal of Pharmaceutical Sciences, no. 7 (July 17, 2024): 1217–25. https://doi.org/10.5281/zenodo.12760617.

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<em>Centella asiatica</em> is beneficial in the treatment of wounds and ulcerous skin abnormalities, <em>Curcuma longa</em> exhibits remarkable anti-inflammatory and antioxidant activity and <em>Terminalia arjuna</em> has antioxidant and astringent property. Rationalizing to this traditional claim, the present study was designed to develop and evaluate polyherbal gel containing alcoholic extract of <em>Centella asiatica, Curcuma longa</em> and<em> Terminalia arjuna.</em> <em> </em>The individual herbs were evaluated for their standard specification according to the Herbal Pharmacopoeia of

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Das, Tama, Mahuli Manna, and Anandamoy Rudra. "Formulation and characterization of papaya leaf gel." GSC Biological and Pharmaceutical Sciences 10, no. 3 (2020): 089–94. https://doi.org/10.5281/zenodo.4279713.

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The study was designed for ethanolic extraction of papaya leaf, phytochemical screening of the extract, formulation of papaya leaf gel by using carbopol 934 and characterization of the herbal gel. The fresh papaya leaves were collected and extracted by maceration process using ethanol as a solvent. The extract was analysed by UV spectrophotometer and IR spectroscopy for identification of phytochemical compounds. Then the phytochemical evaluation was performed and the presence of glycoside, tannins, flavonoids and saponins were observed. The herbal gel was prepared by using carbopol 934 polymer

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Reddy, K. v. Ramana, and M. V. Nagabhushanam. "THE ROLE OF NEEDLE IN FORMULATION OF pH SENSITIVE SWELLABLE MICROBEADS PREPARED WITH HYDROPHILIC POLYMERS FOR ATORVASTATIN AND THEIR CHARACTERIZATION STUDIES." International Journal of Applied Pharmaceutics 9, no. 3 (2017): 20. http://dx.doi.org/10.22159/ijap.2017v9i3.16952.

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Objective: The aim of the study was to develop and characterize mucoadhesive microbeads for oral sustained release of atorvastatin by using hydrophilic polymers and application of different process variables in designing of pH sensitive swellable microbeads.Methods: Microbeads were prepared by ionic gelation method. The compatibility studies of atorvastatin with polymers were investigated by differential scanning calorimeter and fourier transform infrared spectroscopy studies. In this work process variable like optimization of curing agents and their quantity, effect of rpm, and their influenc

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Afifah, Hani, and Setyo Nurwaini. "Uji Aktivitas Antijamur Gel Serbuk Lidah Buaya (Aloe vera L.) Berbasis Carbopol 934 Terhadap Candida albicans dan Trichophyton mentagrophytes." Pharmacon: Jurnal Farmasi Indonesia 15, no. 2 (2019): 42–51. http://dx.doi.org/10.23917/pharmacon.v15i2.7658.

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Fungal infections that occur in the skin and nails were caused by fungi such as Candida albicans and Trichophyton mentagrophytes. Aloe vera contains saponins and acemannan that were effective as an antifungal. This study aims to determine the effect of carbopol concentration variation on aloe vera gel to antifungal activity of Candida albicans and Trichophyton mentagrophytes.Aloe vera powder was obtained from freeze drying aloe vera juice which had been frozen. Aloe vera powder was formulated in gel form using carbopol base with concentration 0.5; 1.0; 1.5; and 2.0 %w/w. The aloe vera gel was

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Gowripattapu, Sridevi, Anusha Nallamilli, and Ashokbabu K. S. "FORMULATION AND EVALUATION OF CAPTOPRIL BIOADHESIVE MICROSPHERES." INDIAN DRUGS 58, no. 09 (2021): 70–72. http://dx.doi.org/10.53879/id.58.09.12410.

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In the present work, captopril microspheres using HPMCK100M, HPMCK15M and Carbopol 934 as copolymers were formulated by ionic cross linking technique (ionotropic gelation method) to deliver captopril via oral route. The technique was successfully employed to fabricate captopril microspheres and provides characteristic advantage over conventional microsphere method, which involves an “all-aqueous” system and thus avoids residual solvents in microspheres. Other methods utilize larger volume of organic solvents are costly and hazardous. Micromeritic studies revealed that the mean particle size wa

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Kavitha., K. *. Kavitha. T. Reshma Fathima. K. "PREPARATION AND EVALUATION OF HERBAL GEL FORMULATION OF CISSUS VITIGINEA LEAF." Journal of Pharma Research 7, no. 7 (2018): 179–81. https://doi.org/10.5281/zenodo.1322964.

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<strong><em>ABSTRACT</em></strong> <strong><em>H</em></strong><em>erbal medicines are still being main stay about 75-80% of this world population. Mostly, In developing countries of primary health care due to better cultural acceptability and better compatibility with human body, reduced side effects. Herbal medicines are consist of plant and its parts to treat injuries, diseases or illness which is used to prevent, treat the ailments or to promote the health, healing. A drug or formulation made from plants which are used for any to such purpose. Herbal medicines are oldest form of healthcare

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Sachan, A. K., A. Gupta, K. Kumari, and A. Ansari. "FORMULATION AND CHARACTERIZATION OF MICROSPHERES OF NITAZOXANIDE BY CHEMICAL CROSSLINKING METHOD." Journal of Drug Delivery and Therapeutics 8, no. 5 (2018): 190–99. http://dx.doi.org/10.22270/jddt.v8i5.1850.

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The work investigated the design and evaluation of microspheres of Nitazoxanide by Ionotropic gelation technique met. 32 Factorial designs were used and concentration of polymer carbopol-934 (X1) and Ethyl cellulose (X2) were selected as the independent variables. The surface morphology study by SEM indicated that microspheres were spherical with smooth surface. There was no interaction between the drug and polymers, as studied by FTIR study. The prepared microspheres were characterized by entrapment efficiency, particle size micromeritic properties. It was observed that on increasing polymer

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Waghulde, Vishakha, and Ravindranath Saudagar. "FORMULATION DEVELOPMENT AND EVALUATION OF pH TRIGGERED IN SITU OPHTHALMIC GEL OF BESIFLOXACIN HYDROCHLORIDE." Journal of Drug Delivery and Therapeutics 8, no. 5 (2018): 313–21. http://dx.doi.org/10.22270/jddt.v8i5.1874.

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The aim of the present work was to formulation and evaluation of pH Triggered in-situ Ophthalmic Gel of Besifloxacin Hydrochloride to overcome the drawbacks obtained by conventional eye drop. There are two independent variables were used i.e. Carbopol 934 and HPMC K100. Carbopol 934 were used as gelling agent and HPMC K100 were used as bioadhesive polymer. Besifloxacin Hydrochloride shows activity against a wide range of Gram-positive and negative ocular pathogens: examples are Corynebacterium pseudodiphtheriticum, Moraxella lacunata, Staphylococcus aureus, Staphylococcus epidermidis, Streptoc

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Gopikrishna, Addanki, B. Ramu, G. Srikanth, and Bigala Rajkamal. "Formulation of Isoniazide Sustained Release Formulation by Using Carbopol 934 P." INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH 1, no. 02 (2016): 60–69. http://dx.doi.org/10.21477/ijapsr.v1i2.10177.

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The aim of the present study was to develop sustained release formulation of Isoniazide to maintain constant therapeutic levels of the drug for over 12 hrs. Various polymers such as Guar gum, HPMCK100 M, PEG 6000 and Carbopol 934 p were employed as polymers. Isoniazide dose was fixed as 100 mg. Total weight of the tablet was considered as 400 mg. Polymers were used in the concentration of 100, 150 and 200 mg. All the formulations passed various physicochemical evaluation parameters and they were found to be within limits. Whereas from the dissolution studies it was evident that the formulation

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Morrin, Mary, and Owen P. Ward. "Studies on interaction of Carbopol-934 with hyphae of Rhizopus arrhizus." Mycological Research 92, no. 3 (1989): 265–72. http://dx.doi.org/10.1016/s0953-7562(89)80064-4.

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Chinatangkul, Nawinda, Narumol Phosrithong, Nantana Nuchtavorn, Teedanai Rattanapit, Chonnawat Mongkol, and Poompat Chutipanyaboot. "Formulation and Physicochemical Evaluation of Topical Preparations Containing Extract of Clerodendrum disparifolium." Advanced Materials Research 1060 (December 2014): 95–98. http://dx.doi.org/10.4028/www.scientific.net/amr.1060.95.

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Clerodendrum disparifolium is a Thai herbal medicine, which is used for the treatment of insect bites and sting reactions by applying finely crushed leaves to the inflamed area. However, this usage is inconvenient. The study aimed to develop gel-and cream-based formulations containing 0.5 %w/v of C. disparifolium extract, and evaluate their physicochemical properties. Different topical formulations were prepared using Carbopol 934 for gels and stearic acid for creams by varying their concentrations. The results showed that gel-based formulation containing Carbopol 934 in the range of 0.5-1.0 %

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Bhandari, Saloni, and Kamal Singh Rathore. "Formulation and evaluation of nano-ethogel of silver sulfadiazine for treatment of topical burns." IP International Journal of Comprehensive and Advanced Pharmacology 7, no. 4 (2023): 195–202. http://dx.doi.org/10.18231/j.ijcaap.2022.038.

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The present study deals with the formulation of ethosomal suspension containing silver sulfadiazine, followed by its incorporation into a hydrogel, leading to the formulation of a novel vesicular nano-ethogel of silver sulfadiazine for the treatment of topical burns. Silver Sulfadiazine ethosomes were prepared by the hot method suggested by Elka Touitou. This ethosomal suspension was loaded into hydrogel made of Carbopol 934 in a ratio of 1:1. Carbopol 934 was chosen as a gelling agent as it do not cause any sort of skin irritation. The nanoethosomal formulations containing SSD were evaluated

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Prusty, Amaresh, Chinmaya Keshari Sahoo, Sanjit Kumar Senapati, Priyanka Singh, and Gyanranjan Behera. "Formulation and Characterization of Methyldopa Floating Tablets Using Polymeric Excipients: A Study on Gastroretentive Drug Delivery System." Jordan Journal of Pharmaceutical Sciences 18, no. 2 (2025): 423–36. https://doi.org/10.35516/jjps.v18i2.2718.

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This research aims to develop a novel gastro retentive drug delivery system (GRDDS) that can prolong the drug release of methyldopa. In the present research tablets are prepared by direct compression method using carbapol 934 and HPMC K100M polymer, by the use effervescent (for Formulations F1, F2, F3, and F4) and non-effervescent (F5) technology. One of the medications used to treat hypertension is methyldopa, a sympatholytic drug that acts centrally having short half-life of 2 h. Sedation, nausea, and vomiting are some of the drug's side effects that occur as a result of its frequency of its

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Kalbhare, Shankar, Rohit K. Pawar, Vivekkumar K. Redasani, Amita B. Yadav, Vishal R. Mohite, and Vaibhav B. Kadam. "Role of Aminated Derivatives of Natural Gum in Release Modulating Matrix System of Losartan Potassium." International Journal of Pharmaceutical Sciences and Nanotechnology(IJPSN) 15, no. 6 (2022): 6204–15. http://dx.doi.org/10.37285/ijpsn.2022.15.6.3.

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Objective: The investigation aimed to synthesize amino derivatives of various natural gums like Xanthan gum and Tamarind gum for using them as a release modulating polymer in the formulation of the hydrophilic matrix system of losartan potassium and to find the best amongst them. Developing oral sustained release matrix tablets for a drug with a constant release rate has always been a challenge to the pharmaceutical technologist.  Materials and Methods: Release modulating hydrophilic matrix tablets of losartan potassium were prepared by wet granulation method. A total number of 6 formula

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Roda, Ashutosh, Prabhakara Prabhu, and Akhilesh Dubey. "DESIGN AND EVALUATION OF BUCCAL PATCHES CONTAINING COMBINATION OF HYDROCHLOROTHIAZIDE AND ATENOLOL." International Journal of Applied Pharmaceutics 10, no. 2 (2018): 105. http://dx.doi.org/10.22159/ijap.2018v10i2.24460.

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Objective: Buccal patch is a non-dissolving thin matrix modified release dosage form which was developed to administer into the unconscious and less co-operative patients.Methods: The mucoadhesive buccal patches of hydrochlorothiazide (HCZ) and atenolol (ATN) were prepared by solvent casting technique using various concentrations of sodium alginate, hydroxyl propyl methyl cellulose, carbopol 934P and sodium carboxy methyl cellulose polymer and polyvinyl alcohol as a backing layer. The formulated patches were evaluated for their physicochemical parameters like thickness, weight variation, surfa

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Vasudev, Jitendra Sharma* Mayur Gokul Jayswal Raza Khan Dr. Mohd. Rehan Deshmukh Prof. (Dr.) G. J. Khan. "Formulation And Evaluation of Gel Containing Zinc Oxide Nanoparticle of Ketoconazole With Aqueous Honey Solution." International Journal in Pharmaceutical Sciences 1, no. 10 (2023): 44–53. https://doi.org/10.5281/zenodo.8419318.

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The aim and objective of the present study was to formulate and evaluate Ketoconazole Nanoparticle. Prepared Ketoconazole loaded zinc oxide nanoparticle. The prepared Nanoparticle formulation was evaluated for particle size and Polydispersity index. The prepared Nanoparticle further formulation gel was prepared with Carbopol 934 and Carbopol 940 Polymers. The honey used as antimicrobial and antifungal agent. The prepared Formulation was evaluated Drug content, viscosity. Spreadability, pH, In vitro Drug release study and Stability studies, antifungal activity. Particle size analysis showed tha

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Sadeq, Zainab Ahmed, and Nawal Ayash Rajab. "STUDYING THE EFFECT OF DIFFERENT VARIABLES ON THE FORMULATION OF MUCOADHESIVE BUCCAL PATCHES OF CAPTOPRIL." International Journal of Applied Pharmaceutics 9, no. 2 (2017): 16. http://dx.doi.org/10.22159/ijap.2017v9i2.16345.

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Objective: The objective of this research was to formulate the captopril as mucoadhesive buccal films for hypertension treatment and studying the effect of different variables on the physical and mechanical behavior of the prepared films.Methods: The bucco-adhesive patches were prepared using hydroxyl propyl methyl cellulose K4 (HPMC) as film forming a polymer with secondary polymer included carbopol 934 and eudragit RL100. The patches were prepared by a solvent casting method and evaluated for the weight variation, surface pH, mechanical properties, content, uniformity, ex-vivo mucoadhesive s

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Lin, Cheng-Xian, Shao-Yen Ko, and F. K. Tsou. "Experimental Investigation of the Laminar Flow Heat Transfer Enhancement in a Small-Scale Square Duct With Aqueous Carbopol Solutions." Journal of Heat Transfer 118, no. 3 (1996): 555–61. http://dx.doi.org/10.1115/1.2822667.

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This paper presents results of an experimental study on the heat transfer enhancement in laminar flow of non-Newtonian fluids, aqueous Carbopol-934 solutions through a small-scale square duct. The square duct is a top-wall heated configuration with a hydraulic diameter of 0.4 cm. The aqueous Carbopol solutions examined are those neutralized, and have a polymer concentration range of 1000–2000 wppm. It is shown that the enhanced heat transfer behavior of the Carbopol solutions within low Reynolds number range is different from that within relatively high Reynolds number range. There exists a li

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Suhail, Muhammad, Yi-Han Hsieh, Yu-Fang Shao, Muhammad Usman Minhas, and Pao-Chu Wu. "Formulation and In-Vitro Characterization of pH-Responsive Semi-Interpenetrating Polymer Network Hydrogels for Controlled Release of Ketorolac Tromethamine." Gels 7, no. 4 (2021): 167. http://dx.doi.org/10.3390/gels7040167.

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Ketorolac tromethamine is a non-steroidal anti-inflammatory drug used in the management of severe pain. The half-life of Ketorolac tromethamine is within the range of 2.5–4 h. Hence, repeated doses of Ketorolac tromethamine are needed in a day to maintain the therapeutic level. However, taking several doses of Ketorolac tromethamine in a day generates certain complications, such as acute renal failure and gastrointestinal ulceration. Therefore, a polymeric-controlled drug delivery system is needed that could prolong the release of Ketorolac tromethamine. Therefore, in the current study, pH-res

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Sarukh, Vikram S., SHIVAPPA N. NAGOBA, S. S. Hindole, K. D. Kaudewar, and Digamber R. More. "FORMULATION AND EVALUATION OF HERBAL GEL CONTAINING Allium cepa EXTRACT." Journal of Drug Delivery and Therapeutics 9, no. 4-s (2019): 492–96. http://dx.doi.org/10.22270/jddt.v9i4-s.3300.

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Herbal medicines widely improved for primary health care because of better cultural acceptability and better compatibility with human body and lesser side effects. The aim of present study was to formulate and evaluate of herbal gel containing Allium cepa extract. Topical gel formulation was designed by using Allium cepa extract and carbopol 934 as a gelling agent and different excipients. The herbaceous plant Allium cepa (onion). It has great health significance and is consumed for nutritional and health benefits for last centuries. It contains flavonoids compound. Plant extract used for prev

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