Relevant bibliographies by topics / Carboxylic acids Metabolism

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Carboxylic acids Metabolism'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Carboxylic acids Metabolism"

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Iwami, Y., S. Hata, N. Takahashi, and T. Yamada. "Difference in Amounts between Titratable Acid and Total Carboxylic Acids Produced by Oral Streptococci during Sugar Metabolism." Journal of Dental Research 68, no. 1 (January 1989): 16–19. http://dx.doi.org/10.1177/00220345890680010101.

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The acid produced by the resting cells of Streptococcus mutans NCTC 10449 and HS 6 and S. sanguis ATCC 10556 during sugar metabolism was estimated with a pH-stat and a carboxylic acid analyzer. Lactic, formic, acetic, pyruvic, and carbonic acids were detected in the reaction mixtures, but propionic, citric, succinic, iso-butyric, butyric, iso-valeric, and valeric acids were not detected. The amount of titratable acid estimated by alkaline titration with the pH-stat was larger than the amount of total carboxylic acids estimated with the carboxylic acid analyzer. The difference in quantity betwe
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Goyal, R., R. Tardif, and J. Brodeur. "Influence of a cysteine prodrug, L-2-oxothiazolidine-4-carboxylic acid, on the urinary elimination of mercapturic acids of ethylene oxide, dibromoethane, and acrylonitrile: a dose–effect study." Canadian Journal of Physiology and Pharmacology 67, no. 3 (March 1, 1989): 207–12. http://dx.doi.org/10.1139/y89-035.

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Metabolic disposition of ethylene oxide, dibromoethane, and acrylonitrile in rats after acute exposure was studied by examining the relationship between dose and urinary metabolites, and by establishing the influence of a glutathione precursor, L-2-oxothiazolidine-4-carboxylic acid (OTCA), on the above relationship. Respective urinary metabolites, hydroxyethylmercapturic acid, cyanoethylmercapturic acid, thiocyanate, and ethylene glycol, were quantified to estimate the extent to which each compound was metabolized. The animals were given either ethylene oxide (0.34, 0.68, or 1.36 mmol/kg), dib
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Sarkar, Omprakash, A. Naresh Kumar, Shikha Dahiya, K. Vamshi Krishna, Dileep Kumar Yeruva, and S. Venkata Mohan. "Regulation of acidogenic metabolism towards enhanced short chain fatty acid biosynthesis from waste: metagenomic profiling." RSC Advances 6, no. 22 (2016): 18641–53. http://dx.doi.org/10.1039/c5ra24254a.

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Darnell, Malin, and Lars Weidolf. "Metabolism of Xenobiotic Carboxylic Acids: Focus on Coenzyme A Conjugation, Reactivity, and Interference with Lipid Metabolism." Chemical Research in Toxicology 26, no. 8 (July 5, 2013): 1139–55. http://dx.doi.org/10.1021/tx400183y.

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Beaulieu, Pierre L., René Coulombe, James Gillard, Christian Brochu, Jianmin Duan, Michel Garneau, Eric Jolicoeur, et al. "Allosteric N-acetamide-indole-6-carboxylic acid thumb pocket 1 inhibitors of hepatitis C virus NS5B polymerase — Acylsulfonamides and acylsulfamides as carboxylic acid replacements." Canadian Journal of Chemistry 91, no. 1 (January 2013): 66–81. http://dx.doi.org/10.1139/cjc-2012-0319.

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Acylsulfonamide and acylsulfamide as surrogates for the carboxylic acid function of N-acetamide-indole-6-carboxylic acids were evaluated as allosteric inhibitors of hepatitis C virus (HCV) NS5B polymerase. Several analogs displayed excellent antiviral potency against both 1a and 1b HCV genotypes in cell-based subgenomic replicon assays. Structure–activity relationships (SAR) are discussed in the context of the crystal structure of an inhibitor − NS5B polymerase complex. Absorption, distribution, metabolism, and excretion pharmacokinetic (ADME-PK) properties of this class of inhibitors are also
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Omran, Arthur, Cesar Menor-Salvan, Greg Springsteen, and Matthew Pasek. "The Messy Alkaline Formose Reaction and Its Link to Metabolism." Life 10, no. 8 (July 28, 2020): 125. http://dx.doi.org/10.3390/life10080125.

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Sugars are essential for the formation of genetic elements such as RNA and as an energy/food source. Thus, the formose reaction, which autocatalytically generates a multitude of sugars from formaldehyde, has been viewed as a potentially important prebiotic source of biomolecules at the origins of life. When analyzing our formose solutions we find that many of the chemical species are simple carboxylic acids, including α-hydroxy acids, associated with metabolism. In this work we posit that the study of the formose reaction, under alkaline conditions and moderate hydrothermal temperatures, shoul
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Knights, Kathleen M., Matthew J. Sykes, and John O. Miners. "Amino acid conjugation: contribution to the metabolism and toxicity of xenobiotic carboxylic acids." Expert Opinion on Drug Metabolism & Toxicology 3, no. 2 (April 2007): 159–68. http://dx.doi.org/10.1517/17425255.3.2.159.

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Bock, Susanne, Ulrich A. Sedlmeier, and Klaus H. Hoffmann. "Metabolism of absorbed short-chain carboxylic acids by the freshwater oligochaete Tubifex tubifex." Comparative Biochemistry and Physiology Part B: Comparative Biochemistry 92, no. 1 (January 1989): 35–40. http://dx.doi.org/10.1016/0305-0491(89)90309-x.

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Knights, Kathleen M. "ROLE OF HEPATIC FATTY ACID:COENZYME A LIGASES IN THE METABOLISM OF XENOBIOTIC CARBOXYLIC ACIDS." Clinical and Experimental Pharmacology and Physiology 25, no. 10 (October 1998): 776–82. http://dx.doi.org/10.1111/j.1440-1681.1998.tb02152.x.

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Arun, Viswanath, Takashi Mino, and Tomonori Matsuo. "Metabolism of Carboxylic Acids Located in and around the Glycolytic Pathway and the TCA Cycle in the Biological Phosphorus Removal Process." Water Science and Technology 21, no. 4-5 (April 1, 1989): 363–74. http://dx.doi.org/10.2166/wst.1989.0238.

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Anaerobic batch experiments were performed to measure the profile of various parameters when phosphorus accumulating sludge acclimatized under anaerobic-aerobic operation is fed with malic, lactic, pyruvic, propionic and succinic acids - carboxylic acids that lie in the vicinity of the Glycolytic pathway and the Tricarboxylic acid cycle - two pathways central to the utilization of organics as sources of energy and carbon in most microorganisms. Carbon dioxide gas produced during substrate uptake was also measured. In most cases, intra-cellular carbohydrate reserves are consumed and the NADH2 t
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Dissertations / Theses on the topic "Carboxylic acids Metabolism"

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Rocha, Sandra Carla. "Avaliação das perspectivas terapêuticas do ácido L-tiazolidina-4-carboxílico, um análogo de prolina, na infecção de camundongos pelo Trypanosoma cruzi." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/42/42135/tde-16082011-160411/.

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Trypanosoma cruzi é dependente de prolina para diversos processos tal como metabolismo energético, invasão celular, diferenciação e resistência a estresse osmótico, metabólico e oxidativo. O ácido L-tiazolidina-4-carboxílico (T4C), um análogo estrutural da prolina, inibe competitivamente o transporte deste aminoácido em T. cruzi, e interage sinergicamente com fatores de estresse que ocorrem ao longo do seu ciclo de vida. Aqui nós avaliamos o efeito de T4C na infecção de camundongos pelo T. cruzi. Foi observada uma redução de 49% do pico parasitêmico de animais infectados e tratados com dose ún
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Li, Chien-Ming. "In Vitro and in Vivo Pharmacology of 4-Substituted Methoxybenzoyl-Aryl-Thiazoles (SMART) and 2-Arylthiazolidine-4-Carboxylic Acid Amides (ATCAA)." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1281966183.

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Hermant, Paul. "Les acides hydroxamiques comme molécules bioactives. Conception, synthèse, propriétés pharmacocinétiques et évaluation biologique." Thesis, Lille 2, 2017. http://www.theses.fr/2017LIL2S021.

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Dans le monde biologique la fonction acide hydroxamique est retrouvée dans les champignons, les levures, les bactéries et les plantes comme agent sidérophore. La propriété des acides hydroxamiques de lier les métaux est exploitée en chimie médicinale dans des stratégies d’inhibition de métalloenzymes à zinc. Ainsi, les acides hydroxamiques sont largement étudiés dans différentes aires thérapeutiques telles qu’en infectiologie, parasitologie, oncologie, cardio-métabolique et dans les maladies inflammatoires. La mise sur le marché d’acides hydroxamiques inhibiteurs des HDACs, tels que le vorinos
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Wu, Cheng-Hsueh, and 吳政學. "Pharmacokinetics of carbadox and determination of its metabolite ( quinoxaline-2-carboxylic acid; QCA ) in pigs following a single dose and multiple in-feed dosing." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/62693073412975175936.

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碩士<br>國立屏東科技大學<br>獸醫學系所<br>96<br>The tissue distribution and residue depletion of carbadox and its metabolite ( quinoxaline-2-carboxylic acid, QCA ) were investigated in swine after a single oral dose of 3.5 mg/kg body weight of carbadox and multiple dose ( 2 weeks ) in-feed ( 55 ppm ) administration. Plasma, muscle, liver and kidney were sampled pre and post-treatment and subsequently analyzed for carbadox and QCA concentrations using liquid chromatography with tandem mass spectrometry ( LC-MS-MS ). The limits of detection of carbadox and QCA were 0.002 and 0.180 ng/g, the limits of quantitat
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Books on the topic "Carboxylic acids Metabolism"

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Winter, Klaus, and J. Andrew C. Smith. Crassulacean Acid Metabolism: Biochemistry, Ecophysiology and Evolution. Springer, 2011.

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Chalmers, R. A. Organic Acids in Man: The Analytical Chemistry, Biochemistry and Diagnosis of the Organic Acidurias. Springer, 2011.

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3

Beardsley, Grant D. Elimination of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid when normalized to urinary creatinine. 1990.

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Beardsley, Grant D. Elimination of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid when normalized to urinary creatinine. 1990.

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Book chapters on the topic "Carboxylic acids Metabolism"

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Wermuth, Bendicht. "Inhibition of Aldehyde Reductase by Carboxylic Acids." In Enzymology and Molecular Biology of Carbonyl Metabolism 3, 197–204. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4684-5901-2_22.

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Rogosa, Morrison, Micah I. Krichevsky, and Rita R. Colwell. "Carboxylic Acid or Ester Metabolism." In Springer Series in Microbiology, 174–81. New York, NY: Springer New York, 1986. http://dx.doi.org/10.1007/978-1-4612-4986-3_30.

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Yang, Shang Fa. "Metabolism of 1-Aminocyclopropane-1-Carboxylic Acid in Relation to Ethylene Biosynthesis." In Plant Nitrogen Metabolism, 263–87. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-0835-5_8.

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Honma, M., Y. J. Jia, Y. Kakuta, and H. Matsui. "Metabolism of 1-Aminocyclopropane-1-Carboxylic Acid by Penicillium Citrinum." In Biology and Biotechnology of the Plant Hormone Ethylene II, 33–34. Dordrecht: Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4453-7_7.

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Pech, Jean-Claude, Mondher Bouzayen, Gilbert Alibert, and Alain Latché. "Subcellular Localization of 1-Aminocyclopropane-1-Carboxylic Acid Metabolism in Plant Cells." In Biochemical and Physiological Aspects of Ethylene Production in Lower and Higher Plants, 33–40. Dordrecht: Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-1271-7_4.

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6

Sposito, Garrison. "Soil Humus." In The Chemistry of Soils. Oxford University Press, 2016. http://dx.doi.org/10.1093/oso/9780190630881.003.0007.

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Biomoleculesare compounds synthesized to sustain the life cycles of organisms. In soil humus, they are usually products of litter degradation, root excretion, and microbial metabolism, ranging in molecular structure from simple organic acids to complex biopolymers. Organic acids are among the best-characterized biomolecules. Table 3.1 lists five aliphatic (meaning the C atoms are arranged in open-chain structures) organic acids associated commonly with the soil microbiome. These acids contain the unit R—COOH, where COOH is the carboxyl groupand R represents either H or an organic moiety. The carboxyl group can lose its proton easily within the normal range of soil pH (see the third column of Table 3.1) and so is an example of a Brønsted acid. The released proton, in turn, can attack soil minerals to induce their decomposition (see Eq. 1.2), whereas the carboxylate anion (COO-) can form soluble complexes with metal cations, such as Al3+, that are released by mineral weathering [for example, in Eq. 1.7, rewrite oxalate, C2O42-, as (COO-) 2]. The total concentration of organic acids in the soil solution ranges up to 5 mM. These acids tend to have very short lifetimes because of biocycling, but they abide as a component of soil humus, especially its water-soluble fraction, because they are produced continually by microorganisms and plant roots. Formic acid (methanoic acid), the first entry in Table 3.1, is a monocarboxylic acid produced by bacteria and found in the root exudates of maize. Acetic acid (ethanoic acid) also is produced microbially—especially under anaerobic conditions—and is found in root exudates of grasses and herbs. Formic and acetic acid concentrations in the soil solution range from 2 to 5 mM. Oxalic acid (ethanedioic acid), which is ubiquitous in soils, and tartaric acid (D- 2,3-dihydroxybutanedioic acid) are dicarboxylic acids produced by fungi and excreted by plant roots; their soil solution concentrations range from 0.05 to 1 mM. The tricarboxylic citric acid (2-hydroxypropane- 1,2,3-tricarboxylic acid) is also produced by fungi and excreted by plant roots. Its soil solution concentration is less than 0.05 mM.
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Arun, Viswanath, Takashi Mino, and Tomonori Matsuo. "METABOLISM OF CARBOXYLIC ACIDS LOCATED IN AND AROUND THE GLYCOLYTIC PATHWAY AND THE TCA CYCLE IN THE BIOLOGICAL PHOSPHORUS REMOVAL PROCESS." In Water Pollution Research and Control Brighton, 363–74. Elsevier, 1988. http://dx.doi.org/10.1016/b978-1-4832-8439-2.50038-9.

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"The Hydrolysis of Carboxylic Acid Esters." In Hydrolysis in Drug and Prodrug Metabolism, 365–418. Zürich: Verlag Helvetica Chimica Acta, 2006. http://dx.doi.org/10.1002/9783906390444.ch7.

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"The Hydrolysis of Carboxylic Acid Ester Prodrugs." In Hydrolysis in Drug and Prodrug Metabolism, 419–534. Zürich: Verlag Helvetica Chimica Acta, 2006. http://dx.doi.org/10.1002/9783906390444.ch8.

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YANG, S. F., Y. LIU, L. SU, G. D. PEISER, N. E. HOFFMAN, and T. McKEON. "METABOLISM OF 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID." In Ethylene and Plant Development, 9–21. Elsevier, 1985. http://dx.doi.org/10.1016/b978-0-407-00920-2.50006-8.

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Conference papers on the topic "Carboxylic acids Metabolism"

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Martynenko, Yulia, and Oleksii Antypenko. "Design of Hydrogenated Isoindolylalkyl(Alkaryl-, Aryl-)Carboxylic Acids with Quinazoline Fragment, that Modify the Carbohydrate Metabolism." In International Youth Science Forum “Litteris et Artibus”. Lviv Polytechnic National University, 2018. http://dx.doi.org/10.23939/lea2018.01.155.

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De Clerck, F., R. Van de Wiele, B. Xhonneux, L. Van Gorp, Y. Somers, W. Loots, J. Beetens, J. Van Wauwe, E. Freyne, and P. A. J. Janssen. "PLATELET TXA2 SYNTHETASE INHIBITION AND TXA2/PROSTAGLANDIN ENDOPEROXIDE RECEPTOR BLOCKADE COMBINED IN ONE MOLECULE (R 68070)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643465.

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F 68070, an oxime-alkane carboxylic acid derivative (Janssen Pharmaceutica), is a potent inhibitor of thromboxane A2 (TXA2) synthetase activity (IC50 in vitro against thrombin-stimulated human platelets in plasma : R 68070 : 2.9 x 10-8 M; CGS 13080 : 6 x 10-8 M; OKY-1581 : 8.2 x 10-8 M; dazmegrel : 2.6 x 10-8 M; dazoxiben : 2.3 x 10-8 M).The compound specifically inhibits platelet TXA2 synthetase activity (14C-arachidonic acid metabolism by washed human platelets) without effect on the cyclo-oxygenase, lipoxygenase (platelets, RBL cells) or prostacyclin synthetase activities (rat aortic rings)
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