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Journal articles on the topic 'Carcinoma breast'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Sume, Bickes Wube, Wubshet Assefa, and Yoseph Merkeb Alamneh. "Early onset, delayed diagnosis and laterality of breast carcinoma: Evidence from a tertiary care hospital." SAGE Open Medicine 10 (January 2022): 205031212211146. http://dx.doi.org/10.1177/20503121221114623.

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Objectives: To assess age at onset, delayed diagnosis and laterality of breast carcinoma among women at Debre Markos Comprehensive Specialized Hospital, North West Ethiopia. Methods: Hospital-based descriptive study was conducted on 120 breast carcinoma cases at pathology department of Debre Markos Comprehensive Specialized Hospital, from October 2019 to December 2021. The women aware of symptoms until first medical consultation time was asked. The height and weight of the women were measured using the height and weight scale. The attending physician examined both breasts and regional lymph no

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2

Sica, Gabriel, Patrick L. Wagner, Nassar Altorki, et al. "Immunohistochemical Expression of Estrogen and Progesterone Receptors in Primary Pulmonary Neuroendocrine Tumors." Archives of Pathology & Laboratory Medicine 132, no. 12 (2008): 1889–95. http://dx.doi.org/10.5858/132.12.1889.

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Abstract Context.—Lung and breast carcinomas are among the most prevalent cancers. Advances in cancer therapies can provide survival benefit and be potentially curative, even in metastatic disease. Due to the high prevalence of these carcinomas, it is not unusual to encounter lung nodule(s) in a patient with breast carcinoma, and distinguishing between primary and metastatic disease is critical for management/treatment. Occasionally neuroendocrine differentiation is present in breast carcinoma, making its distinction from pulmonary/nonpulmonary neuroendocrine tumors in the lung difficult. Obje

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3

Valdes, Edna K., Sheldon M. Feldman, and Nina Krassilnik. "Neuroendocrine Tumor of the Breast." American Surgeon 72, no. 2 (2006): 185–87. http://dx.doi.org/10.1177/000313480607200219.

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Mammary carcinoid is an uncommon neoplasm. It accounts for approximately 5 per cent of all breast carcinomas. It is well-known that neuroendocrine elements can be demonstrated in ductal and lobular carcinoma. However, it is still controversial whether mammary carcinoid tumors should be considered a distinct clinical entity or be treated as a variant of conventional breast carcinoma. Differentiating these lesions from benign lesions such as epithelial hyperplasia and papillomas can be challenging at times. We present a case of neuroendocrine tumor of the breast.

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Koufopoulos, Nektarios I., Ioannis Boutas, Abraham Pouliakis, et al. "The “Forgotten” Subtypes of Breast Carcinoma: A Systematic Review of Selected Histological Variants Not Included or Not Recognized as Distinct Entities in the Current World Health Organization Classification of Breast Tumors." International Journal of Molecular Sciences 25, no. 15 (2024): 8382. http://dx.doi.org/10.3390/ijms25158382.

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Breast carcinoma is the most common cancer in women. Nineteen different subtypes of breast carcinomas are recognized in the current WHO classification of breast tumors. Except for these subtypes, there are a number of carcinomas with special morphologic and immunohistochemical features that are not included in the 5th WHO classification, while others are considered special morphologic patterns of invasive breast carcinoma of no special type. In this manuscript, we systematically review the literature on four different subtypes of invasive breast carcinoma, namely lymphoepithelioma-like breast

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5

Manjula, N., C. Jayanthi, S. Srivani, and Damodara Kumaran. "Spectrum of Special Variants of Breast Carcinoma and Differentiated Ductal Carcinomas with their Immunohistochemistry Profile in a Tertiary Care Centre." Journal of Medical Sciences and Health 10, no. 1 (2024): 16–25. http://dx.doi.org/10.46347/jmsh.v10.i1.23.317.

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Background: Breast cancer is a diverse disease with varying characteristics in morphology, presentation, treatment, and prognosis. It constitutes 25% of cancers in Indian women. This study delves into rare special variants and differentiated ductal carcinomas, focusing on their unique histological features and molecular profiles. Aim: To scrutinize the spectrum of special forms of breast carcinoma and their immunohistochemistry (IHC) profile. Material and methods: A retrospective analysis of all the breast carcinomas over a period of 11 months was carried out. The clinical, gross, microscopic

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Priya, V. Sri Lakshmi, and Priavadhana Rajan Prasaad. "Tubulo- lobular carcinoma: a rare mixed invasive carcinoma of." International Journal of Research in Medical Sciences 5, no. 6 (2017): 2818. http://dx.doi.org/10.18203/2320-6012.ijrms20172496.

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Tubulo-lobular carcinoma is a rare variant of invasive carcinoma of breast, exhibiting the features of both tubular and lobular component. It accounts for about 1% of mammary carcinomas. Study report a case of 39-year-old female with lump in the left breast for 6 months. Histopathologically it was diagnosed as tubulo-lobular carcinoma of breast. Hence histopathology plays an important role in diagnosis and treatment of mammary carcinomas.

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7

Ahmad, Noorzuliana, Arasaratnam A. Shantini, Iqbal Hussain Rizuana, and Muhammad Rohaizak. "Encapsulated Papillary Carcinoma: A Rare Case Report and Its Imaging Features." Diagnostics 12, no. 9 (2022): 2098. http://dx.doi.org/10.3390/diagnostics12092098.

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Papillary lesions in the breasts are uncommon and have a wide range of pathologies. Due to diverse non-specific findings radiologically and histologically, papillary neoplasms are always a challenge to radiologists. Encapsulated papillary carcinomas (EPCs) of the breast, also known as intracystic papillary carcinomas, are a subgroup of intraductal papillary lesions of the breast. We present a case of a painless right breast lump with the aim to describe a rare encapsulated papillary carcinoma and its imaging features.

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8

Kaushik, Manish, Samir Bhattacharya, Subrata Kumar Sahu, Parth Ketankumar Shah, Subrata Chakraborty, and Sunipa Ghosh Pradhan. "Metaplastic carcinoma of the breast: a case report." International Surgery Journal 9, no. 10 (2022): 1760. http://dx.doi.org/10.18203/2349-2902.isj20222603.

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Metaplastic carcinoma is a rare but heterogeneous group of neoplasm of breast, accounting for about 1% of all breast carcinomas. Metaplastic carcinomas may be either low-grade tumors (e.g., adenosquamous carcinoma or spindle cell carcinoma), or high-grade tumors (e.g., squamous cell carcinoma, or spindle cell carcinoma). We report a case of metaplastic breast carcinoma in a 72-year-old lady. The clinical, radiological and histological characteristics are discussed.

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9

Kito, Katsumi, Toshiharu Maeda, Keiko Ninomiya, et al. "HER2-Positive Metaplastic Spindle Cell Carcinoma Associated with Synchronous Bilateral Apocrine Carcinoma of the Breast." Case Reports in Pathology 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/310829.

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Apocrine carcinoma, which is strictly defined as over 90% of tumor cells showing apocrine differentiation, is a rare variant of breast cancer. Here we report an uncommon case in which apocrine carcinomas developed concurrently in both breasts; in addition, a sarcomatoid spindle cell lesion was coincident in the right breast. Both apocrine carcinomas were immunohistochemically negative for estrogen receptor (ER) and progesterone receptor (PgR), but diffusely positive for androgen receptor (AR), GCDFP-15, and HER2. The presence of intraductal components in bilateral carcinomas and the absence of

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10

Rissanen, T., T. Tikkakoski, A. L. Autio, and M. Apaja-Sarkkinen. "Ultrasonography of invasive lobular breast carcinoma." Acta Radiologica 39, no. 3 (1998): 285–91. http://dx.doi.org/10.1080/02841859809172196.

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Purpose: To review the US findings in invasive lobular breast carcinoma which is often difficult to diagnose clinically and mammographically Material and Methods: The mammographic and US findings in 63 cases of pure invasive lobular carcinoma diagnosed at our institution in 1990-1996 were reviewed retrospectively. The US findings were classified as positive, negative or indeterminate for malignancy Results: Forty-nine of the 63 lobular carcinomas (78%, 95% CI 65.5-87.3%) were US-positive, and 51 (81%, CI 95% 69.1-89.8%) were mammography-positive. The US visibility of the carcinomas was affecte

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11

Shah, Bhushan Anil, Nagendra Yadav, Kandarpa Akhil, and Firoz Alam. "A rare case report of bilateral synchronous carcinoma breast." International Surgery Journal 4, no. 9 (2017): 3153. http://dx.doi.org/10.18203/2349-2902.isj20173905.

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Bilateral Breast Carcinoma (BBC) is a rare entity with incidence of synchronous carcinoma being 2-5% of all breast malignancies, which is much less than metachronous carcinoma. Synchronicity/metachronicity are usually associated with local and lymphatic spread and with blood-borne spread to lungs, bones and liver. Moreover, BBC are mostly lobular carcinomas but we report a rare case of Infiltrating Ductal Carcinoma (IDC), medullary type as the primary carcinoma. 56-year-old female who presented with a lump in her right breast for 6 months and lump in her left axilla. There was no e/o palpable

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12

Sujata, Singla, Meena Kusum, and Aggarwal Sumeet. "Brachial plexopathy in a case of carcinoma breast: A rare presentation." International Journal of Medical Reviews and Case Reports 3, no. 8 (2018): 504–6. https://doi.org/10.5455/IJMRCR.brachial-plexopathy-breast-carcinoma.

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Brachial plexopathy in breast cancer patients can be due to two main causes; one being tumour infiltration and other being radiation therapy. In literature a lot has been written about radiation induced brachial plexopathy. Primary and secondary tumours of brachial plexus are the most common cause of brachial plexopathy. Plexus neuropathies usually observed in patients with breast cancer at variable time interval following surgery; cause being recurrence and adjuvant radiotherapy; attributing factor being radiation induced fibrosis. We are reporting a case of 65 years old lady of carcinoma bre

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13

Gomez, Mariangela, Kerry Whitting, and Rana Naous. "Lobular breast carcinoma metastatic to the endometrium in a patient under tamoxifen therapy: A case report." SAGE Open Medical Case Reports 8 (January 2020): 2050313X2090720. http://dx.doi.org/10.1177/2050313x20907208.

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Metastatic carcinomas to the uterus are rare and usually originate from nearby gynecologic sites, most commonly from the ovaries. Among non-gynecologic origins, breast tumors are the most frequent primaries, predominantly the lobular carcinoma type. A 69-year-old postmenopausal woman diagnosed with lobular breast carcinoma 5 years ago, status post modified radical mastectomy, and currently on tamoxifen therapy presented with post-menopausal bleeding. Subsequent endometrial biopsy confirmed the diagnosis of metastatic lobular breast carcinoma to the endometrium. Breast carcinomas rarely metasta

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14

SINGLA, SUJATA, KUSUM MEENA, and SUMEET AGGARWAL. "BRACHIAL PLEXOPATHY IN A CASE OF CARCINOMA BREAST: A RARE PRESENTATION." International Journal of Medical Reviews and Case Reports 2, Reports in Surgery and Dermatolo (2018): 1. http://dx.doi.org/10.5455/ijmrcr.brachial-plexopathy-breast-carcinoma.

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15

Rohini, Bhatia, P. A. Singh, Misra Vatsala, Dhingra Vishal, Singhal Mitali, and Sharma Nishant. "Pleomorphic Lobular Carcinoma in a Male Breast: A Rare Occurrence." Pathology Research International 2010 (December 1, 2010): 1–3. http://dx.doi.org/10.4061/2010/871369.

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Carcinoma of male breast is uncommon as it accounts for 0.7% of total breast cancer. The pathology of male breast cancer is remarkably similar to that of cancers seen in women. The same histological subtypes of invasive cancer are present, although papillary carcinomas (both invasive and in situ) are more common and lobular carcinomas are less common. The predominant histological type, in males, as in females, reported in large series has been infiltrating ductal carcinoma with scattered reports of infiltrating lobular carcinoma, all of them of classical type except for a single case of pleomo

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Parada, David, Karla Peña, Francesc Riu, and Pilar Hernandez. "Triple Negative Breast Carcinoma: A Comparative Study between Breast Lesion and Lymph Node Metastases: A Preliminary Study." ISRN Pathology 2011 (July 28, 2011): 1–6. http://dx.doi.org/10.5402/2011/598131.

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Aims and Background. Triple negative breast carcinoma is a genetic and molecular subtype of breast carcinoma with poor prognosis. Some immunohistochemistry studies have been proposed to identify BLBC. Most studies consider primary breast carcinoma but not metastases. Methods. Immunohistochemical characteristics in 11 triple negative breast carcinomas were studied in both primary lesions and lymph node metastases. All cases were reevaluated to estrogen and progesterone receptors and HER2-Neu. An FISH probe for HER2/neu was also performed. Immunohistochemical studies were performed with cytokera

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17

Thomas, M. Albert, Nathaniel Wyckoff, Kenneth Yue, et al. "Two-dimensional MR Spectroscopic Characterization of Breast Cancer In Vivo." Technology in Cancer Research & Treatment 4, no. 1 (2005): 99–106. http://dx.doi.org/10.1177/153303460500400113.

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The major goal of this work was to characterize invasive ductal carcinoma and healthy fatty breast tissues noninvasively using the classification and regression tree analysis (CART) of 2D MR spectral data. 2D L-COSY spectra were acquired in 14 invasive breast carcinoma and 21 healthy fatty breasts using a GE 1.5 Tesla MRI/MRS scanner equipped with a 2-channel phased-array breast MR coil. The 2D spectra were recorded in approximately 10 minutes using a minimum voxel size of 1 ml without any water suppression technique. For healthy breasts, spectra were acquired from at least one fatty region. 2

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18

Agustina, Rohana. "Rare Case of Metaplastic Breast Carcinoma with Squamous Differentiation in Young Female: A Case Report." Sanus Medical Journal 4, no. 1 (2022): 5–8. http://dx.doi.org/10.22236/sanus.v4i1.8090.

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Background. Metaplastic breast carcinoma is a very rare breast cancer, only about 0.2"‘1% of all invasive breast carcinomas. The prognosis of these cancer is poor and aggressive, reported to have lower response rates to conventional adjuvant chemotherapy and a worse clinical outcome after chemotherapy than other forms triple"‘negative breast carcinomas. Histopathologically, metaplastic breast carcinoma has distinct patterns with different outcomes. Among the types of metaplastic carcinoma, squamous cell, high grade spindle cell and high grade adenosquamous carcinoma are associated with the wor

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Agustina, Rohana. "Rare Case of Metaplastic Breast Carcinoma with Squamous Differentiation in Young Female: A Case Report." Sanus Medical Journal 3, no. 1 (2022): 5–8. http://dx.doi.org/10.22236/sanus.v3i1.8090.

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Background. Metaplastic breast carcinoma is a very rare breast cancer, only about 0.2"‘1% of all invasive breast carcinomas. The prognosis of these cancer is poor and aggressive, reported to have lower response rates to conventional adjuvant chemotherapy and a worse clinical outcome after chemotherapy than other forms triple"‘negative breast carcinomas. Histopathologically, metaplastic breast carcinoma has distinct patterns with different outcomes. Among the types of metaplastic carcinoma, squamous cell, high grade spindle cell and high grade adenosquamous carcinoma are associated with the wor

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20

Gautam, Swotantra, Brikha Raj Joshi, Shailesh Adhikary, Sudeep Regmi, and Anju Pradhan. "Male Breast Cancer: A Rare Entity." Journal of Nepal Medical Association 56, no. 212 (2018): 804–7. http://dx.doi.org/10.31729/jnma.3662.

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Male breast carcinoma is a rare malignancy (<1% of all breast carcinomas, 0.2% of all male malignancies). Its common histopathological type is infiltrating carcinoma, not otherwise specified. Three male patients aged 56 (stage –IIIB), 64 (T4bN0M0) and 78 (T2N0MO) years presented with a breast lump within a year. Their hematological and biochemical parameters were within normal limits. Two of them had palpable regional lymph nodes. Male breast carcinoma occurs in older males as in our cases. Two cases showed infiltrating ductal carcinoma, not otherwise specified on histopathological evaluati

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Srebnijs, Andrejs, Sergejs Isajevs, Jānis Eglītis, Viesturs Krūmiņš, Juris Bērziņš, and Uldis Vikmanis. "Distribution And Clinicopathological Features Of Breast Cancer Histological Subtypes In Latvia." Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 69, no. 1-2 (2015): 14–19. http://dx.doi.org/10.1515/prolas-2015-0001.

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Abstract Breast cancer is a heterogenous disease. It consists of several histological subtypes that can be separated by morphology and immunohistochemistry. The aim of our study was to determine the distribution of breast cancer histological and molecular subtypes, and their relationship with clinical and pathological characteristics. A total of 561 patients who underwent breast carcinoma surgical treatment from January 2003 till December 2012 were enrolled in the study. In total, invasive ductal carcinomas not otherwise specified (IDC-NOS) plus invasive ductal carcinomas no special type (IDC-

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Geredeli, Caglayan, Nurgul Yasar, and Abdullah Sakin. "Germline Mutations in BRCA1 and BRCA2 in Breast Cancer Patients with High Genetic Risk in Turkish Population." International Journal of Breast Cancer 2019 (January 1, 2019): 1–7. http://dx.doi.org/10.1155/2019/9645147.

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Background. The guidelines recommend considering the BRCA1 and BRCA2 germline mutations in female patients with breast carcinomas. In this retrospective study, the BRCA1/2 mutation prevalence in high-risk breast carcinoma patients in a Turkish population was investigated. Materials and Methods. In high genetic risk breast carcinoma patients, the BRCA1 and BRCA2 germline mutations were identified by applying next-generation sequencing. Results. The results showed BRCA1/2 mutations in 19% of the total patients. In those with first-degree relatives with breast carcinoma histories, the BRCA1/2 mut

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23

Haupt, Bisong, Jae Y. Ro, and Mary R. Schwartz. "Basal-like Breast Carcinoma: A Phenotypically Distinct Entity." Archives of Pathology & Laboratory Medicine 134, no. 1 (2010): 130–33. http://dx.doi.org/10.5858/134.1.130.

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Abstract Gene microarray profiling of human breast carcinomas has recently categorized invasive breast carcinomas into 5 distinct subtypes; luminal A, luminal B, normal breastlike, human epithelial growth factor receptor 2 (HER2) overexpressing, and basal-like. Basal-like breast carcinomas are characterized by high expression of basal cytokeratins; low or absent expression of estrogen receptor, progesterone receptor, and HER2/neu; and expression of epidermal growth factor receptor (EGFR) and/or c-kit, and they are frequently associated with breast cancer 1 (BRCA1) mutations and poor clinical o

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Rath, Satyajeet. "Sebaceous carcinoma of the male breast." Clinical Oncology Research and Reports 1, no. 1 (2020): 01–04. http://dx.doi.org/10.31579/2693-4787/019.

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Sebaceous carcinoma of the male breast is an exceedingly rare occurrence. Literature is inadequate about the prognosis and treatment of such malignancies. We report histo-pathological and immuno-histochemical (IHC) findings in a case of sebaceous carcinoma of breast of a 60-year-old male. An initial biopsy suggested sebaceous carcinoma. Total mastectomy was performed, followed by local radiotherapy and adjuvant chemotherapy. The receptor status was triple negative. Pan cytokeratin and epithelial membrane antigen were positive, whereas S-100 was focally positive and HMB-45 and Melan A were nega

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Rajput, Dr Neha, Dr S. C. Puranik, and Dr S. H. Khaparde. "Carcinoma of Breast with Neuroendocrine Differentiation: A rare challenging entity." VIMS Health Science Journal 11, no. 3 (2025): 34–36. https://doi.org/10.46858/vimshsj.110307.

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Neuroendocrine breast carcinoma (NEBC), another name for breast carcinoma with neuroendocrine differentiation, is a heterogeneous collection of uncommon tumors that make about 2-5% of all invasive breast carcinomas. Neuroendocrine tumors (NETs) originate in neuroendocrine cells. These cells combine the characteristics of endocrine cells, which produce hormones, and nerve cells. We report a rare case of carcinoma of breast with neuroendocrine differentiation. On microscopy the section of breast tumour specimen showed infiltrating duct carcinoma with area of 50% neuroendocrine differentiation.

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Markopoulos, Christos, Efstratios Kouskos, Helen Gogas, et al. "Diagnosis and Treatment of Intracystic Breast Carcinomas." American Surgeon 68, no. 9 (2002): 783–86. http://dx.doi.org/10.1177/000313480206800910.

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Cystic breast masses are very common in female patients attending breast clinics. Most of them are benign and managed by simple aspiration. We reviewed histology records for the last 12 years to find patients with cystic breast carcinomas and to evaluate special clinical signs that may help to identify patients with this rare entity. Eighteen patients with cystic breast carcinomas were found among 1510 new breast cancer patients (1.19%) who were seen at our Breast Unit during this period. Ten had intracystic papillary carcinoma (0.66% of all breast cancers), seven had cystic degeneration of du

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Choi, Bo Bae, Hyeon Ji Jang, and Song I. Choi. "Basal-like Breast Cancer: Comparison of Imaging Characteristics." Current Medical Imaging Formerly Current Medical Imaging Reviews 16, no. 3 (2020): 241–48. http://dx.doi.org/10.2174/1573405615666181231162938.

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Background: Basal-like carcinoma is one of the breast subtypes that lacks expression of the estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2). It has a poor prognosis and aggressive behavior. It is in a heterogeneous group with various other types of cancer, including metaplastic carcinoma, carcinomas with medullary features, medullary carcinoma, adenoid cystic carcinoma, secretory carcinoma, and invasive carcinoma arising in the setting of BRCA1 mutations. Imaging features of basal-like cancers have not been uniform, and there are no studie

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Ganesan, Keerthini, Sandhya Sundaram, and Leena Dennis Joseph. "Metaplastic carcinoma of the breast." Annals of Pathology and Laboratory Medicine 6, no. 9 (2019): C94–96. http://dx.doi.org/10.21276/apalm.2429.

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Shubhangi D., Sakore, Waghmare Ramesh S., and Kamble R.A. "Digital Dermatoglyphics in Carcinoma Breast." Indian Journal of Anatomy 5, no. 3 (2016): 287–91. http://dx.doi.org/10.21088/ija.2320.0022.5316.15.

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Rosen, Lauren Elizabeth, and Paolo Gattuso. "Neuroendocrine Tumors of the Breast." Archives of Pathology & Laboratory Medicine 141, no. 11 (2017): 1577–81. http://dx.doi.org/10.5858/arpa.2016-0364-rs.

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Primary neuroendocrine tumors of the breast are a rare and underrecognized subtype of mammary carcinoma. Neuroendocrine tumors of the breast occur predominately in postmenopausal women. The tumors are subclassified into well-differentiated and poorly differentiated neuroendocrine tumors, and invasive breast carcinoma with neuroendocrine features. Well-differentiated tumors show architectural similarity to carcinoids of other sites but lack characteristic neuroendocrine nuclei. Poorly differentiated neuroendocrine tumors are morphologically identical to small cell carcinoma of the lung. Neuroen

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Kiss, Orsolya, Anna-Mária Tőkés, Sándor Spisák, et al. "MicroRNA-profiling in breast- and salivary gland-derived adenoid cystic carcinomas." Orvosi Hetilap 154, no. 25 (2013): 963–68. http://dx.doi.org/10.1556/oh.2013.29643.

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Introduction: Adenoid cystic carcinoma is a salivary gland-derived malignant tumor, but rarely it can originate from the breast, too. The salivary gland-derived form shows a very aggressive clinical outcome, while adenoid cystic carcinoma of the breast has mostly a very good prognosis. Aim: The aim of the authors was to compare the miRNA-expression profile of breast- and salivary gland-derived cases. Method: The miRNA-profiles of two salivary gland derived and two breast-derived adenoid cystic carcinoma tissues as well as one normal breast and one salivary gland tissues were analysed using the

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V., Shruthikamal, Reshma S., and Rajesh S. "Adenoid cystic carcinoma right breast: a rare case report." International Surgery Journal 4, no. 10 (2017): 3546. http://dx.doi.org/10.18203/2349-2902.isj20174536.

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Adenoid Cystic carcinoma of the breast is a rare neoplasm accounting for 0.1% of breast carcinomas, and presenting most commonly as a painful breast lump. In contrast to the aggressive nature of adenoid cystic carcinoma at other sites, adenoid cystic carcinoma of the breast has a favourable prognosis, lymph node involvement or distant metastases seldom occur. Treatment is basically of modified radical mastectomy. Chemotherapy, radio therapy and hormonal treatment have been infrequently used. We report a case of 60 years old woman with adenoid cystic carcinoma of the right breast managed with M

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Pandiaraja, Jayabal, and Arumugam Shalini. "A case of bilateral intracystic papillary carcinoma breast." Journal of Cancer Research and Therapeutics 20, no. 3 (2024): 1071–73. http://dx.doi.org/10.4103/jcrt.jcrt_1885_20.

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ABSTRACT Intracystic papillary carcinoma breast is an uncommon breast cancer consisting of 0.5-1.0% of all breast cancers. Papillary carcinoma is further subdivided into intraductal and intracystic papillary carcinoma. Intracystic papillary carcinoma is further divided into pure intracystic papillary carcinoma or associated with in situ carcinoma. The clinical and radiological features of intracystic papillary carcinoma are not specific, hence a high chance of misdiagnosis. Here we report a case of intracystic papillary carcinoma of both breasts which created a diagnostic dilemma.

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Karki, Shovana, Sansar Babu Tiwari, and Alina Basnet. "Evaluation of tumor infiltrating lymphocytes in breast carcinomas." Journal of Pathology of Nepal 12, no. 2 (2022): 1909–12. http://dx.doi.org/10.3126/jpn.v12i2.47200.

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Background: Among the parameters that have a prognostic and/or predictive significance to therapeutic response, in the case of breast carcinoma, the study of tumor-infiltrating lymphocytes in breast carcinomas is emerging. The present study aimed to access the clinicopathological profiles of tumor-infiltrating lymphocytes in patients with primary breast carcinoma. Materials and Methods: Information was collected from the archive of the Department of Pathology, about invasive breast cancers diagnosed between April 2019 –March 2020. Hormone receptor status and Ki-67 index were assessed. For tumo

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Yoshimura, Noriko, Shigeru Murakami, Mayumi Kaneko, Akio Sakatani, Naoki Hirabayashi, and Wataru Takiyama. "Synchronous Bilateral Solid Papillary Carcinomas of the Breast." Case Reports in Surgery 2013 (2013): 1–4. http://dx.doi.org/10.1155/2013/812129.

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We herein report a case of synchronous bilateral solid papillary carcinoma of the breast. A 73-year-old female had a mass that was detected in the right breast on mammography. An ultrasound examination revealed one intracystic tumor in the right breast and two tumors in the left breast. A fine-needle aspiration biopsy of these three tumors was performed, which revealed a diagnosis of malignancy. A magnetic resonance imaging examination of the breasts showed diffuse small nodules surrounding these tumors bilaterally. Bilateral partial mastectomy and a sentinel lymph node biopsy were performed.

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S., Berrada M. Quaboul L. Elhamri Y. Benchamkha M. Khouchani H. Rais. "A Metaplastic Carcinoma of Ectopic Breast In Axilla Mimicking A Cutaneous Epidermoid Carcinoma: A Differential Diagnosis Not To Disregard." British Journal of Pharmaceutical and Medical Research 04, no. 01 (2019): 1636–42. https://doi.org/10.24942/bjpmr.2019.460.

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Metaplastic carcinomas (MC) of the breast constitute a heterogeneous group of tumors, characterized by the presence of squamous or sarcomatoid differentiation. It is a rare type of malignant epithelial neoplasm that arises from the breast, and whose  diagnosis  is based on histology and immunochemistry. Location in ectopic breast tissue (EBT) in axilla is extremely rare, and when it ulcerates, it can mimic  squamous cell carcinoma of skin. We report an unusual clinical case of a 61-year-old woman with metaplastic carcinoma  in  axillary ectopic breast,  falsely di

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Shin, Sandra J., Farrukh S. Sheikh, Patricia A. Allenby, and Paul Peter Rosen. "Invasive Secretory (Juvenile) Carcinoma Arising in Ectopic Breast Tissue of the Axilla." Archives of Pathology & Laboratory Medicine 125, no. 10 (2001): 1372–74. http://dx.doi.org/10.5858/2001-125-1372-isjcai.

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Abstract Mammary carcinoma arising in ectopic breast tissue is an uncommon occurrence. Most reported cases have involved ductal carcinoma, but other types, such as medullary, papillary, and lobular carcinomas, have been described. For pathologists, the diagnosis of mammary carcinoma arising in ectopic breast tissue can be difficult, especially in the axilla, where carcinoma of adnexal origin must be excluded. We describe a 46-year-old woman who developed invasive (juvenile) secretory carcinoma in ectopic right axillary breast tissue and micrometastatic carcinoma in an ipsilateral axillary lymp

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Bitencourt, Almir Galvão Vieira, Eduardo Nóbrega Pereira Lima, Rubens Chojniak, et al. "Correlation between PET/CT results and histological and immunohistochemical findings in breast carcinomas." Radiologia Brasileira 47, no. 2 (2014): 67–73. http://dx.doi.org/10.1590/s0100-39842014000200006.

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Objective To correlate the results of 18F-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) performed with a specific protocol for assessment of breasts with histological/immunohistochemical findings in breast carcinoma patients. Materials and Methods Cross-sectional study with prospective data collection, where patients with biopsy-confirmed breast carcinomas were studied. The patients underwent PET/CT examination in prone position, with a specific protocol for assessment of breasts. PET/CT findings were compared with histological and immunohistochem

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Öhlschlegel, Christian, Katharina Zahel, Doris Kradolfer, Margreth Hell, and Wolfram Jochum. "HER2 genetic heterogeneity in breast carcinoma." Journal of Clinical Pathology 64, no. 12 (2011): 1112–16. http://dx.doi.org/10.1136/jclinpath-2011-200265.

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AimsTo determine the frequency of HER2 genetic heterogeneity according to the recent American Society of Clinical Oncology (ASCO) and College of American Pathologists (CAP) definition (2009) in invasive breast carcinoma, and to identify clinicopathological features that characterise breast carcinomas with HER2 genetic heterogeneity.Methods530 invasive breast carcinomas were retrospectively analysed for HER2 genetic heterogeneity, and investigated for a potential association of HER2 genetic heterogeneity with other HER2 FISH findings, clinicopathological parameters, oestrogen/progesterone recep

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Romanucci, Giovanna, Sara Mercogliano, Elisabetta Carucci, et al. "Low-grade adenosquamous carcinoma of the breast: a review with focus on imaging and management." Acta Radiologica Open 10, no. 4 (2021): 205846012110135. http://dx.doi.org/10.1177/20584601211013501.

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Low-grade adenosquamous carcinoma is a less frequent variant of metaplastic breast carcinoma, incidentally detected during screening and has an age distribution similar to other breast carcinomas. It shares characteristics with both benign and malignant carcinomas: its mammographic and sonographic features are therefore nonspecific. Breast conserving surgery with adjuvant radiation therapy is currently the preferred therapeutic approach. The aim of this review is to describe the imaging and clinical features of low-grade adenosquamous carcinoma for appropriate identification and diagnosis. The

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Choi, April, Philip M. Carpenter, Shefali Chopra, et al. "Spindle cell carcinoma of the breast managed with neoadjuvant AIM: A case report." Rare Tumors 12 (January 2020): 203636132097702. http://dx.doi.org/10.1177/2036361320977021.

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Spindle cell carcinoma (SpC), also known as metaplastic carcinoma—spindle cell type, is a subtype of metaplastic carcinoma. Metaplastic carcinomas of the breast are rare but are thought to be more aggressive than invasive ductal carcinomas. Due to their rarity, there are few randomized trials that can inform any standardized approaches to treatment. Treatment is instead extrapolated from other types of breast cancer or metaplastic carcinomas of different locations. Here we present the first known case report of a patient with spindle cell carcinoma of the breast successfully treated with a sta

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Bergeron, Anthony, Isabelle Desmoulins, Francoise Beltjens, et al. "An exceptional metaplastic lobular breast carcinoma diagnosed through exome sequencing." Journal of Clinical Pathology 73, no. 9 (2020): 597–601. http://dx.doi.org/10.1136/jclinpath-2019-205783.

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Metaplastic breast carcinoma is a rare subtype of breast cancer. This subtype is mostly found in association with poorly differentiated ductal breast carcinomas and rarely with other breast carcinoma types. We report the case of a 69-year-old woman with an exceptional invasive lobular breast carcinoma associated with metaplastic squamous cell bone metastasis occurring 2 years after the initial breast cancer diagnosis. Whole-exome sequencing and subsequent immunohistochemistry of the lesions were used to link the squamous cell bone metastasis of unknown origin to the primary breast carcinoma in

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Ramavath, Krishna, Gopi Singh L, Reshmi Sultana, et al. "Invasive solid papillary carcinoma of breast mimicking as a benign condition: Rare case report." Indian Journal of Pathology and Oncology 10, no. 4 (2023): 431–33. http://dx.doi.org/10.18231/j.ijpo.2023.099.

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Invasive papillary carcinomas of breast are rare tumors. They account for approximately 0.5% of all Invasive breast carcinomas. Invasive papillary carcinomas are commonly present in post-menopause women. These tumors lack the myoepithelial cell layer (MCL) within the papillae or at the periphery of the tumor. The diagnosis is difficult due to different clinical and radiological features. Immunohistochemistry (IHC) is really essential to confirming the diagnosis. We are here presenting one index case of a rare variety of invasive papillary carcinoma of the left breast. We present a case of inva

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Rakha, Emad A., Andrew H. S. Lee, Andrew J. Evans, et al. "Tubular Carcinoma of the Breast: Further Evidence to Support Its Excellent Prognosis." Journal of Clinical Oncology 28, no. 1 (2010): 99–104. http://dx.doi.org/10.1200/jco.2009.23.5051.

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Purpose Although tubular carcinoma (TC) is known to have a favorable prognosis, it is still unknown whether this subtype represents a distinct type of breast carcinoma or whether it behaves like other low-grade luminal A–type breast carcinomas. Methods In this study, we performed a retrospective analysis of a large well-characterized series of breast cancers (2,608 carcinomas) to assess the clinicopathologic and molecular features and prognostic value of TC compared with grade 1 ductal carcinomas of the breast. Results When compared with grade 1 ductal carcinoma (n = 212), TC (n = 102) was mor

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Myes, Deychen, Manupriya Sharma, Chitresh Kumar, and Anita Chaudhary. "RARE PRESENTATION: SYNCHRONOUS PRIMARY BREAST AND THYROID CANCER IN AN ELDERLY MALE." International Journal of Advanced Research 12, no. 07 (2024): 762–67. http://dx.doi.org/10.21474/ijar01/19110.

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Synchronous primary breast and thyroid carcinomas are exceptionally rare, especially in males. This case report presents the first documented instance of synchronous primary breast and thyroid carcinoma in an 89-year-old male. The patient had a right breast mass, cervical lymph nodes and a heterogeneously enhancing lesion in right lobe of thyroid. The histopathological examination confirmed infiltrating ductal carcinoma and metastasis of papillary carcinoma thyroid in cervical lymph node. While hormonal imbalances and genetic mutations have been implicated in synchronous breast and thyroid car

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Ng, Yam Hock, Saadon Ibrahim, and Yee Chin Chai. "A case report of lymphedema as an unusual initial presentation of breast carcinoma." Proceedings of Singapore Healthcare 31 (June 2022): 201010582211115. http://dx.doi.org/10.1177/20101058221111580.

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Breast carcinoma is one of the most common carcinomas among women around the world. Most of the women with breast carcinoma will present with signs and symptoms of breast problems to the health facility. Upper limb swelling is one of the rare initial presentations although it is rather common in patients as a sequelae of breast carcinoma treatment. We herein would like to report a case where a post-menopausal female presented with left upper limb swelling with initial history suggestive of traumatic injury of biceps muscle. Subsequent investigations of ultrasound, mammography, biopsy sample of

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Gil-Santana, Leonardo, Daniela de Almeida Carvalho, and Vladmir Cláudio Cordeiro de Lima. "Abstract P1-08-20: Synchronic invasive lobular breast carcinoma, invasive mammary carcinoma NST, and large cell neuroendocrine carcinoma of the lung." Clinical Cancer Research 31, no. 12_Supplement (2025): P1–08–20—P1–08–20. https://doi.org/10.1158/1557-3265.sabcs24-p1-08-20.

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Abstract Introduction: Synchronous bilateral breast cancer represents 10% of all breast cancers. The occurrence of bilaterality is more common with invasive lobular carcinomas (ILCs). The prognosis appears to be worse when compared unilateral tumors. We describe a rare and challenging clinical case of a patient with three synchronous tumors: bilateral breast carcinomas and a large cell neuroendocrine carcinoma of the lung. Case Report: A sixty-eight-year-old smoker (18 packs-year), post-menopausal, white female was submitted to a screening breast ultrasound that disclosed a single 23 x 18 mm n

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Kulka, Janina, Lilla Madaras, Giuseppe Floris, and Sigurd F. Lax. "Papillary lesions of the breast." Virchows Archiv 480, no. 1 (2021): 65–84. http://dx.doi.org/10.1007/s00428-021-03182-7.

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AbstractPapillary lesions of the breast represent a heterogeneous group of lesions including benign papillomas, papillomas with focal epithelial atypia, fully fledged ductal carcinoma in situ (DCIS) or lobular neoplasia, papillary DCIS, encapsulated papillary carcinomas without or with invasion, solid papillary carcinomas, and invasive papillary carcinomas. A micropapillary pattern characterized by lack of fibrous stalks within the papillae is observed in micropapillary DCIS and invasive micropapillary carcinoma. In addition, a variety of other rare breast lesions reveals a papillary architect

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Elmetwally, Ahmed A., Mennat Allah M. Abdel-Hafeez, Makram M. Hammam, Gamal A. Hafez, Maha M. Atwa, and Mohammed K. El-Kherbetawy. "Immunohistochemical study of proline, glutamic acid and leucine-rich protein 1 (PELP1) in correlation with guanine adenine thymine adenine family member 3 (GATA-3) receptors expression in breast carcinomas." Egyptian Journal of Pathology 43, no. 1 (2023): 53–65. http://dx.doi.org/10.4103/egjp.egjp_2_23.

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Abstract Background Breast cancer is the most common cancer affecting Egyptian women. Guanine adenine thymine adenine family member 3 (GATA-3) and Proline, glutamic acid and leucine-rich protein 1 (PELP1) are both expressed in breast carcinomas. Aim To evaluate GATA-3 and PELP1 proteins expression in breast carcinoma, assess association of both immunohistochemical markers with variable prognostic factors, correlate between GATA-3 and PELP1 expression and assess the diagnostic utility of both markers in breast carcinomas. Subjects and methods The current study was a cross-sectional descriptive

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Renshaw, Andrew A. "Minimal (≤0.1 cm) Invasive Carcinoma in Breast Core Needle Biopsies." Archives of Pathology & Laboratory Medicine 128, no. 9 (2004): 996–99. http://dx.doi.org/10.5858/2004-128-996-mcicib.

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Abstract Context.—Although minimally invasive (microinvasive) carcinoma (≤0.1 cm) of the breast is a well-known and well-characterized entity in excision specimens, the significance of small foci of invasion in breast core needle biopsies has not been well described. Objective.—To define the significance of minimally invasive carcinoma in breast core needle biopsies. Design.—Review of a large series of core needle biopsies for invasive carcinomas measuring 0.1 cm or less and correlation of the results with those of subsequent excision. Setting.—Large community hospital. Results.—From approxima

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