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Journal articles on the topic 'Carcinoma of Gall Bladder'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Darmas, B., S. Mahmud, A. Abbas, and AL Baker. "Is there Any Justification for the Routine Histological Examination of Straightforward Cholecystectomy Specimens?" Annals of The Royal College of Surgeons of England 89, no. 3 (2007): 238–41. http://dx.doi.org/10.1308/003588407x168361.

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INTRODUCTION Gall bladder carcinoma is a rare malignancy that carries a very poor prognosis. Laparoscopic cholecystectomy (LC) is established as the gold-standard treatment for symptomatic gall stones. The aim of the study was to assess the incidence of gall bladder carcinoma and the possibility of reducing the routine histological examination of gall bladder specimens. PATIENTS AND METHODS Pathology laboratory data of gall bladder specimens over a period of 5 years (June 2000 to July 2005) were analysed retrospectively. The case notes were retrieved in all cases of malignancies. RESULTS The t

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2

Patil, Nanda, and Vaidehi Nagar. "Mucinous Carcinoma of Gall Bladder – A Rare Case Report." International Journal of Health Sciences and Research 11, no. 6 (2021): 326–28. http://dx.doi.org/10.52403/ijhsr.20210648.

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Background: Mucinous carcinoma of the gall bladder is a very rare type of gall bladder carcinoma. It is characterized by production of extracellular mucin >50% of tumour volume. Case Report: We report a case of primary mucinous carcinoma of gall bladder in a 60-year-old female patient who was diagnosed clinically as acute cholecystitis. Histopathological examination gave the definitive diagnosis in this case. Conclusion: Mucinous carcinoma of gall bladder exhibit significant clinicopathological difference from conventional adenocarcinoma of gall bladder and display aggressive clinical behav

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3

Iqbal, Sahar, Fariha Sahrish, Samra Sameen, Firdous Iqbal, Sarosh Aitzaz, and Sara Masood Cheema. "UNEXPECTED GALL BLADDER CARCINOMA – A SURPRISING HISTOPATHOLOGICAL DIAGNOSIS." Pakistan Journal of Pathology 33 (September 3, 2022): 83–87. http://dx.doi.org/10.55629/pakjpathol.v32i3.696.

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Objective: To determine the frequency of gall bladder carcinoma incidentally diagnosed in patients undergoing routine laparoscopic cholecystectomy. Material and Methods: Histopathology section of Pathology Department, Azra Naheed Medical College Raiwind Road, Lahore from January 2018 to July 2021. A total of 214 simple or laparoscopic cholecystectomy specimens were included. Detailed gross & microscopic examination was done. All diagnoses including benign histopathological findings and incidental gall bladder carcinoma were analyzed. The important findings like resection margin involvement

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Vagholkar, Ketan. "Carcinoma of the gall bladder." International Surgery Journal 10, no. 7 (2023): 1258–61. http://dx.doi.org/10.18203/2349-2902.isj20231800.

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Gallbladder carcinoma is fifth most common gastrointestinal malignancy. Main indication for cholecystectomy is gallstone disease. Majority of gallbladder carcinomas are diagnosed during the course of histopathological evaluation of specimens obtained at cholecystectomy. Accomplishing radical cholecystectomy is advisable in these patients. Technically difficult gallbladder dissection during the course of laparoscopic surgery should raise a high suspicion of malignancy. Specimen retrieval bags should be used in all cases to avoid external spillage of bile giving rise to port side metastasis. A g

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Sajeevan, Sanjay, Biswajyoti Das, Yanpothung Yanthan, et al. "Sacrum metastasis in carcinoma gall bladder: an unusual presentation." International Journal of Research in Medical Sciences 8, no. 5 (2020): 1884. http://dx.doi.org/10.18203/2320-6012.ijrms20201498.

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Disseminated blood-borne metastases from carcinoma of the gall bladder are uncommon and usually occur late. The most common site of extra-abdominal metastasis is lung followed by brain. Skeletal metastases in carcinoma gall bladder are very rare. To date there have only been a few case reports of bone metastasis in carcinoma gall bladder at the time of presentation. Authors here present a rare case of carcinoma gall bladder that progressed to isolated sacrum metastasis.

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Nagar, Neeti, Meetu Agrawal, Megha Tandon, and Junaid Ansar. "Squamous Versus Adenosquamous Carcinoma in Gall Bladder." Annals of Pathology and Laboratory Medicine 6, no. 11 (2019): C113–115. http://dx.doi.org/10.21276/apalm.2607.

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7

Tangde, Ashwini Radhakishan, Santosh Govind Rathod, Anil R. Joshi, and Rajan S. Bindu. "Mucinous adenocarcinoma of gall bladder: a case report." International Journal of Research in Medical Sciences 5, no. 11 (2017): 5082. http://dx.doi.org/10.18203/2320-6012.ijrms20174977.

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Gall bladder carcinoma is the fifth most common malignancy of gastrointestinal tract. Mucinous carcinoma of gall bladder is very rare variant of gall bladder carcinoma. Only 20 cases of mucinous carcinoma reported till now. We report one such case of 55yr old female patient presented to our hospital with complaining of pain in right hypochondriac region and vomiting since, one month. Radiological examination revealed neoplastic thickening of gall bladder neck with cholelithiasis. Cholecystectomy was performed and specimen showed glistening grey white infiltrative firm solid mass at the neck of

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Rai, Saurabh, Chandra Shekhar, Osman Musa, et al. "Role of Tumour Markers Carbohydrate Antigen 19-9, Carcinoembryonic Antigen, & Alpha Fetoprotein in Carcinoma Gall Bladder." Journal of Evolution of Medical and Dental Sciences 10, no. 10 (2021): 719–23. http://dx.doi.org/10.14260/jemds/2021/154.

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BACKGROUND Gallbladder cancer is recognised as an irreversible malignancy with a high fatality rate. The highest incidence of gall bladder carcinoma is seen in India and Chile, and relatively low level in many Western countries. Gall bladder carcinoma has an extremely poor prognosis, increasing incidence, and diagnosed at an advanced stage despite recent advances in diagnostic modalities. Considering the high rate of mortality attributable mainly to late detection of disease at an advanced stage, early diagnosis remains to be one of the most important determinants of the outcome. This study wa

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Degloorkar, Sarang, Sanjay Parab, Bimal Shah, Sunita Prasad, and Shivanjali Gore. "A retrospective single centre study on histopathological analysis of cholecystectomy specimens in a tertiary care centre in India." International Surgery Journal 10, no. 10 (2023): 1616–20. http://dx.doi.org/10.18203/2349-2902.isj20232983.

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Background: Gall bladder carcinoma is the 5th most common gastrointestinal malignancy which has a poor 5-year survival rate, carrying dismal prognosis. Diagnosing chronic cholecystitis from gall bladder cancer is challenging. Early detection of gall bladder carcinoma allows for the possibility of radical resection surgery, which has been shown to increase patient survival. Methods: A retrospective histopathological analysis was conducted at a tertiary care centre to evaluate the incidence of gall bladder carcinoma. A total of 1728 cholecystectomy samples were evaluated from all age groups for

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10

Zeeshan Nahid, Sadaf Abbas, Asfa Shams, and Kafil Akhtar. "Clear Cell Carcinoma Gall Bladder: Mimicker of Xanthogranulomatous Cholecystitis." International Journal of Histopathological Interpretation 11, no. 2 (2022): 1–6. http://dx.doi.org/10.56501/intjhistopatholinterpret.v11i2.491.

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The incidence of clear cell carcinoma of gall bladder is very low. The mean age of diagnosis is 60 years. The potential cause of clear cell carcinoma of gall bladder has been shown to be associated with gallstones. It is difficult to determine that clear cell morphology is due to metastasis, notably from clear cell renal cell carcinoma or whether these are primary tumor of the gall bladder. We report a case of clear cell carcinoma of the gall bladder in a 56-year-old female, who presented with abdominal discomfort along with pain and bloating that was aggravated mainly after the meal, with an

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11

Meenakshi, Pathak, Gupta Nimisha, and Pathak Sunit. "Incidentally Discovered Gall Bladder Carcinomas on Routine Histopathology Following Laparoscopic Cholecystectomy." International Journal of Pharmaceutical and Clinical Research 15, no. 8 (2023): 705–10. https://doi.org/10.5281/zenodo.11493313.

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<strong>Background:</strong> Gall bladder carcinoma accounts for 98% of all the gall bladder malignancies and it is the fifth most common malignancy of the gastrointestinal tract worldwide. Most incidental gall bladder cancers are detected only after pathological examination of the excised surgical specimens. This study was aimed at detecting the incidence of gall bladder carcinomas which were diagnosed incidentally on histopathological examination of gall bladders which were sent for gall stone disease and cholecystitis in our center and the need for routine versus selective histopatholo

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12

Dey, Poulami, Ritu Sarkar, Monoj Kumar Deka, and Arindam Das. "Ki-67 Expression in Premalignant and Malignant Lesions of Gallbladder in Southern Part of Assam." International Journal of Pharmaceutical and Clinical Research 16, no. 5 (2024): 682–86. https://doi.org/10.5281/zenodo.11409388.

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<strong>Introduction:</strong> Gallbladder cancer is the most common malignancies of the biliary tract and among the gastrointestinal malignancies. Gall stones, pyloric and intestinal metaplasia have been found to be associated with gall bladder carcinoma. Ki-67 is a good marker for cell proliferation and its expression is correlated with various lesions of gall bladder. <strong>Aim:</strong> The aim of the study is to assess the ki-67 expression in different malignant and premalignant lesions of gall bladder. <strong>Materials and Methods:</strong> The retrospective s

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13

Bharat, Jain, Hathila Nipa, Satyam Monica, and Vohra Apurva. "Prevalence of Gallbladder Carcinoma According to TNM Classification." International Journal of Pharmaceutical and Clinical Research 14, no. 3 (2022): 117–26. https://doi.org/10.5281/zenodo.13843280.

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<strong>Introduction</strong>: Gall Bladder Carcinoma is an aggressive malignant condition that is found mainly among the elderly population. In average, the affected population is about 65 to 70 years old which is found to comprise of 2/3rd of the biliary tract carcinoma. Due to high incidence, it is needed to be properly staged and managed. TNM classification and AJCC’s staging system can be used in this regard which is the most accepted one. <strong>Aims and Objectives</strong>: The study intended to find out the number of patients in each staging and how the staging varies with

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14

Sutradhar, Probir Kumar, Subrata Saha, Dipanwita Saha, et al. "Association of gallbladder carcinoma with gallstone and its prevalence in a tertiary care teaching hospital." Mediscope 8, no. 2 (2021): 87–93. http://dx.doi.org/10.3329/mediscope.v8i2.55315.

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Objective: To see the association of gallstones with gallbladder carcinoma and its prevalence in patients undergoing surgery for cholelithiasis. Methods: This cross-sectional observational study was conducted from July 2012 to June 2013 at the Department of Surgery, Mymensingh Medical College Hospital, Mymensingh with 150 cases of cholelithiasis. Results: Of 150 cases those were operated for gall bladder stone disease, 8 (eight) were found to have carcinoma of gall bladder i.e. prevalence was 5.3%. On ultrasound, only three (37.5%) patients were suspected as gall bladder carcinoma pre-operativ

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15

Vance Kynshikhar, Danquale, and Chaman Lal Kaushal. "Case of Xanthogranulomatous Cholecystitis Mimicking Carcinoma Gall Bladder." International Journal of Science and Research (IJSR) 10, no. 6 (2021): 1293–95. https://doi.org/10.21275/sr21615151715.

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16

Choudhury, Madhusmita, Gargi Roy Choudhury, Monoj K. Deka, and Shah A. Sheikh. "A histopathological evaluation of gall bladder cancer with special reference to HER2/neu and E-cadherin in Southern part of Assam." International Journal of Research in Medical Sciences 9, no. 5 (2021): 1368. http://dx.doi.org/10.18203/2320-6012.ijrms20211871.

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Background/Objective: Gall bladder carcinoma (GBC) is an aggressive malignancy with high mortality and aggressive course, with palliation as the only available option. The signs and symptoms of gall bladder arcinoma are not specific and often present late. Diagnosis is, therefore, often made at advanced stage with poorer outcomes. Identifying biomarkers and cancer specific cellular targets, that will pave the way for novel therapeutic approaches and early diagnosis for gall bladder carcinoma, is urgently needed. Proto-oncogenes (HER-2) and E-Cadherin are commonly deregulated in gallbladder can

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17

Ullah, Zia, Ahmad Arsalan Tahir, Muhammad Tayyab, Muhammad Ishfaq, Sabeen Nasir, and Rubab Naseer. "Frequency of Gall Bladder Carcinoma after Cholecystectomy for Symptomatic Gallstone Disease in Tertiary Care Hospital, Peshawar." Pakistan Armed Forces Medical Journal 73, no. 6 (2023): 1562–64. http://dx.doi.org/10.51253/pafmj.v73i6.8549.

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Objective: To determine the frequency of gall bladder carcinoma after cholecystectomy for symptomatic gallstone disease and to determine the most commonly affected age group and its gender-based predominance in our population. Study Design: Cross sectional study. Place and Duration of Study: Histopathology Lab, Tertiary Care Teaching Hospital, Peshawar Pakistan, from Jan 2015 to Jan2021. Methodology: A total of 995 patients of all age groups and of either gender were included in our study. The demographics, clinical data of the patient (signs, symptoms and ultrasound report), and histopatholog

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18

Ferdousi, Shamima, and Sadia Armin Khan. "Primary Squamous Cell Carcinoma of Gall Bladder: A Case Report." Ibrahim Medical College Journal 8, no. 2 (2016): 61–63. http://dx.doi.org/10.3329/imcj.v8i2.26681.

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Squamous cell carcinoma of the gall bladder is rare. It accounts for less than 12.7 % of all cases of gall bladder cancer. Pure squamous cell carcinoma is even less common with a reported incidence of 3.3%. We present a case of 70 years-old man with decreased appetite, vomiting and fever associated with right upper quadrant pain for two months. Ultrasonography of the abdomen revealed a distended gallbladder with multiple calculi along with large hyperechoic area of sludge. Provisional diagnosis was cholelithiasis with empyema of gall bladder. Cholecystectomy was done. Histopathological examina

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19

Nazir, Muhammad Shahbaz, Nasir Mehmud Wattoo, Maria Nawaz, Nadia Shabnam, Ahmed Hassaan Malik, and Muhammad Usman Nadeem. "Association of Gall Bladder Carcinoma with Gall Stones; A Single Centre Study in a Tertiary Care Hospital." Pakistan Armed Forces Medical Journal 75, no. 2 (2025): 286–89. https://doi.org/10.51253/pafmj.v75i2.9699.

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Objective: To evaluate the occurrence of gall bladder carcinoma and its association with gall stones in patients undergoing cholecystectomies. Study Design: Cross sectional study. Place and Duration of Study: Army Liver Transplant Unit, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Feb 2020 to Jun 2022. Methodology: We enrolled 500 patients, between the ages of 18 to 80 years, presenting to outpatient department of a tertiary care hospital, with complaints of gall stone disease, and planned for cholecystectomy. Detailed history was obtained, along with laboratory investigations and

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20

Bargotya, Mona, Ankita Mehta, Payel Das, and Ashish Sachan. "Primary pure squamous cell carcinoma of the gall bladder – a case report of rare and aggressive entity with adverse prognosis." European Journal of Clinical and Experimental Medicine 18, no. 1 (2020): 59–63. http://dx.doi.org/10.15584/ejcem.2020.1.13.

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Introduction. The most common malignancy of the biliary tract is gall bladder carcinoma and the main subtype according to the histological classification is Adenocarcinoma. Pure squamous cell carcinoma of the gall bladder is very rare entity accounting for only 1.1-3.7% of the gall bladder carcinomas. It is highly malignant with poor prognosis due to high proliferative rate and local invasiveness to the adjacent organs. The patients are usually diagnosed at an advanced stage with a bulky tumor owing to its aggressive behavior. Aim. In this paper, we describe a female patient with primary pure

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Sarma, Usha, Leena Talukdar, and Nayana Bora. "Incindental Detection of Gall Bladder Carcinoma Post Cholecystectomy Done for Benign Lesions- A Study in a Tertiary Care Centre of North East India." Asian Pacific Journal of Cancer Biology 8, no. 3 (2023): 227–30. http://dx.doi.org/10.31557/apjcb.2023.8.3.227-230.

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Background: Incidentally discovered gall bladder cancer (IGBC) is defined as the gall bladder cancer diagnosed during or after the cholecystectomy done for unsuspected benign lesion of GB. There is high incidence of gall bladder carcinoma in North, East, North East and central Indian regions as compared to South and West India.Methods: The present study was conducted at the Gauhati Medical College and hospital (GMCH), Guwahati, Assam for a period of 1 year (January - December 2022). 0.5% cholecystectomy specimens were microscopically diagnosed as incidental gall bladder carcinoma in our study.

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Hardeep, Balyan, Nishan Satwik, Swaroop Mittal Gyanendra, and Arya Anubhav. "Incidence of Carcinoma Gall Bladder in Patients with Cholelithiasis in Tertiary Care Hospital, Hapur." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 1855–62. https://doi.org/10.5281/zenodo.12605263.

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<strong>Background: </strong>Gallbladder carcinoma is a rare complication of cholelithiasis. The aim of this study was to find out the incidence incidental carcinoma gall bladder in patients undergoing cholecystectomy for cholelithiasis. <strong>Methods:</strong> A total number of 430 patients who were operated at tertiary care hospital, Hapur over a period of 18 months, starting from July 2020 till December 2021, were included in this study. Cases admitted in various surgical wards were clinically evaluated and confirmed by ultrasonography for cholelithiasis. <strong>Resul

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Vitetta, L., A. Sali, P. Little, and L. Mrazek. "Gallstones and Gall Bladder Carcinoma." ANZ Journal of Surgery 70, no. 9 (2000): 667–73. http://dx.doi.org/10.1046/j.1440-1622.2000.01926.x.

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Kyriacou, E. "Carcinoma of the gall-bladder." Journal of Gastroenterology and Hepatology 14, no. 3 (2002): 215–19. http://dx.doi.org/10.1046/j.1440-1746.1999.01838.x.

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Shrestha, Santosh, Deepak Sharma, Roshan Ghimire, Dhiresh Kumar Maharjan, and Prabin Bikram Thapa. "Incidental carcinoma of gallbladder following laparoscopic cholecystectomy: A single center study." Grande Medical Journal 2, no. 1 (2020): 28–31. http://dx.doi.org/10.3126/gmj.v2i1.45701.

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Background: Gallbladder adenocarcinoma is the most common malignant tumor of the biliary tract. Most of gall bladder cancers are detected incidentally only after pathological examination of the excised surgical specimens. In this study we investigated the characteristics of incidental gallbladder cancers in our center. Material & methods: We retrospectively reviewed all of the cholecystectomy specimens in sent for histopathology following laparoscopic cholecystectomy in the study period from January 2015 to October 2019. Clinicopathological characteristics were extracted from the patients'

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A. C., Senthil Kumar, Balamurali S., and Reshma S. "Early gallbladder carcinoma with cholelithiasis: a rare case report." International Surgery Journal 4, no. 7 (2017): 2363. http://dx.doi.org/10.18203/2349-2902.isj20172799.

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Gall bladder carcinoma is an exceedingly rare and fatal cancer with a high mortality rate. Detecting gall bladder carcinoma in early stages can be difficult, despite improvements in ultrasound and computed tomography (CT) imaging. Most diagnoses of gallbladder carcinoma are made at advanced stages, with majority being found incidentally during surgery for cholelithiasis. The presented case demonstrates suspicion of Gallbladder carcinoma pre-operatively.

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Atiq, M., M. M. Safa, R. S. Komrokji, et al. "Improvement of survival in VA patients with gall bladder cancer given chemotherapy." Journal of Clinical Oncology 24, no. 18_suppl (2006): 4132. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.4132.

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4132 Background: Gallbladder carcinoma, though rare, has very poor prognosis. Most of patients with gall bladder carcinoma present with either unresectable disease or metastasis. Median survival in gall bladder carcinoma has been documented to be 6 months in SEER data. There is no data available on the outcome of Veterans’ Affair (VA) patients with gall bladder carcinoma. Impact of chemotherapy in adjuvant and metastatic setting is not well-studied. Methods: We used the VA Central Cancer Registry (VACCR) to analyze VA patients with Gall Bladder cancer diagnosed between 1995 and 2005. The refer

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Mahajan, Divya, and Theepanraj Kamaraj. "A Rare Case Report of Carcinoma Gall Bladder with Brain Metastasis in 18 Year Old Male." Asian Pacific Journal of Cancer Biology 8, no. 3 (2023): 313–15. http://dx.doi.org/10.31557/apjcb.2023.8.3.313-315.

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Introduction: Worldwide carcinoma gall bladder is 22nd most common cancer and 17th most common cause of death according to GLOBOCAN 2018 data. In 2018, the estimated incidence was 97,000 for men and 122,000 for women. Risk of carcinoma gall bladder from birth till 74 year is 0.26% for women and 0.25% for men. Here we are reporting a case of carcinoma gall bladder of 18 year old male who presented to us in opd with extensive brain metastasis and liver metastasis. Case presentation: This case report refers to 18 year old male presented to us with chief complaint of pain in right hypochondrium fo

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Dr., Rai Muhammad Fazal-ur-Rehman Khan Dr.Urooj Fatima Adnan Dr. Sundus Amena. "RISK OF CA GALL BLADDER IN PATIENTS WITH CHOLELITHIASIS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 3574–75. https://doi.org/10.5281/zenodo.1243881.

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<strong><em>Objective: </em></strong><em>The aim of our research was frequency determination in the patients of </em><em>gall bladder experiencing the cholelithiasis surgery.</em> <strong><em>Place and Duration: </em></strong><em>The research was descriptive by design and it was completed in the time of two years starting from January, 2015 to December, 2017 in Allied hospital, Faisalabad.</em> <strong><em>Patients and Methods: </em></strong><em>We included two hundred </em><em>cholelithiasis patients who experienced cholecystectomy in the setting of our research. We included both male and fem

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S, Agrawala. "Demographic and Clinico-Pathological Profile of Gall Bladder Carcinoma Patients in a Tertiary Care Hospital in Odisha." Haematology International Journal 5, no. 2 (2021): 1–7. http://dx.doi.org/10.23880/hij-16000194.

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Background: Gall Bladder cancer ranks as sixth most common digestive tract cancer with very poor survival rate. The data from India shows a very wide variation in incidence. The purpose of this study is to determine the Demographic and Clinico- pathological Profile of Gall Bladder carcinoma patients in a tertiary care hospital in Odisha. Methods: We retrospectively analyzed 103 patients of gall bladder carcinoma from our Hospital database between 2016 and 2019. The demographic and epidemiological characteristics were analyzed. Socioeconomic status was determined by the modified Kuppuswamy’s so

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Tazeen, Jeelani, Amin Jibran, and Reshi Ruby. "Incidental Gall Bladder Carcinoma in Routine Cholecystectomy Cases: Need for Histopathology." International Journal of Research and Review 6, no. 3 (2019): 12–15. https://doi.org/10.5281/zenodo.3987809.

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Gall bladder carcinoma accounts to be the 5th most common cancer of digestive tract. The clinical manifestations of gall bladder carcinoma are generally indistinguishable from those associated with cholecystitis or cholelithiasis. Incidental GBC (IGBC) refers to GBC not suspected before or at operation and not even on gross examination of the GB specimen and is only detected for the first time on histo-pathological examination. Study was conducted in the department of pathology Government medical college Srinagar Jammu and Kashmir and was two year retrospective study. The main aim was to study

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Ray, M. S., B. S. Deepak, Aneeta Jassar, and Kunjan Pathania. "Pleomorphic giant cell adeno-carcinoma gall bladder: a histological rarity and a surgical dilemma." International Surgery Journal 4, no. 4 (2017): 1497. http://dx.doi.org/10.18203/2349-2902.isj20171171.

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Undifferentiated pleomorphic giant cell adeno-carcinoma of the gall bladder (GB) is an extremely rare condition and is usually an incidental diagnosis. Here, we describe a rare case of gall bladder carcinoma in a 50 year old lady who presented with upper abdominal pain and palpable lump in the right hypochondrium. Computed tomography and Ultrasonography of the abdomen showed an ill-defined giant heterogeneous soft tissue mass involving gall bladder and adjacent liver parenchyma with obvious regional adenopathy. Metastatic work-up was abnormal and the patient underwent radical cholecystectomy.

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Agarwal, Anshoo, and Yanina Singh. "Cyclin D1 and Its Expression in Neoplastic Gall Bladder Lesions." Med Phoenix 5, no. 1 (2020): 71–74. http://dx.doi.org/10.3126/medphoenix.v5i1.31421.

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Carcinoma of Gall bladder is an infrequent tumour of the gastrointestinal tract and has long been recognized as a highly lethal disease. Tumour markers are glycoprotein that can be determined in blood, saliva, urine and tissues by certain immunological methods. Cyclin D1 is such a marker which is seen to be expressed in various neoplasms. Its role has also been confirmed in gall bladder neoplastic conditions. The onset and progression of gallbladder carcinoma are accompanied with multiple genetic changes that result in qualitative and quantitative alterations in individual gene expression. Imm

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Shukla, Anju, Fatema Shareh Naqvi, and Shashank Chaudhary. "Multifocal biliary carcinoma; whether synchronous or metastatic: A need to conquer." IP Journal of Diagnostic Pathology and Oncology 8, no. 2 (2023): 117–19. http://dx.doi.org/10.18231/j.jdpo.2023.027.

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Multiple synchronous primary carcinoma involving gall bladder, liver and common bile duct are rare and difficult to differentiate with hepatic and extrahepatic bile duct metastasis from single primary. Radiological features, molecular landscape, and even integrated mutational profiling are not of much help. We describe a case of 48-year-old male who presented with jaundice and follow up CT scan raised the suspicion of gall bladder carcinoma with hepatic metastasis. Peroperative frozen section examination revealed adenocarcinoma with involvement of cystic duct margin; however revised common duc

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Ivanov, Yuryi V., and Fedor G. Zabozlaev. "Rare case of gall bladder squamous cell carcinoma in pacient with cholelithic illness." Journal of Clinical Practice 3, no. 2 (2021): 26–30. http://dx.doi.org/10.17816/clinpract83704.

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The clinical case of the patient with squamous cell carcinoma of gall bladder in a combination with cholelithic illness is described. Presurgical diagnostics of gall bladder cancer is difficult, demands a complex and careful assessment of disease anamnesis, a clinical sings, results of laboratory and tool analysis. At impossibility to exclude gall bladder cancer in the presence of a cholelithic illness in all cases operative treatment is needed.

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Biswas, PK, PK Das, MH Rahman, and DK Mahanta. "Incidental Carcinoma Gall Bladder in Patients Undergoing Cholecystectomy for Chronic Calculus Cholecystit is." TAJ: Journal of Teachers Association 22, no. 2 (2009): 223–26. http://dx.doi.org/10.3329/taj.v22i2.37728.

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Carcinoma gall bladder (CaGb) is the most common neoplasm of biliary tract. Aetiology of this tumour is complex, but there is a strong association with gall stones. The symptoms are seldom suggestive of cancer and imaging techniques are usually equivocal. This study was conducted to see the frequency of cancer of gall bladder in patients undergoing surgery for chronic cholecystitis with cholelithiasis in different age and sex groups in our population. An observational study was conducted in the department of surgery unit-II Rajshahi Medical College Hospital and Mukti Clinic Rajshahi on the pat

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Shafique, Sadaf, Raheel Khan, Raees Abbas, and Bakhtawer Mehmood. "Necessity of routine histopathological examination of gall bladder specimens after elective cholecystectomy: An experience at Tertiary Care Hospital of Southern Punjab Pakistan." Professional Medical Journal 27, no. 06 (2020): 1171–75. http://dx.doi.org/10.29309/tpmj/2020.27.06.3846.

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Objectives: Few centers adopt a selective approach in sending these specimens to pathology department for histopathology whereas it is a routine procedure in our setup. In our study, few unexpected cases of adenocarcinoma of gall bladder were seen during investigation of results of pathological examination of gall bladder specimens. Study Design: A retrospective histopathological analysis of gall bladder specimens removed during elective cholecystectomy for benign diseases was done. Setting: Department of Pathology, Quaid-e-Azam Medical College/Bahawal Victoria Hospital Bahawalpur. Period: 1st

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Pandey, Pratibha, Uzma Sayyed, Rohit Tiwari, Neelam Pathak, Mohammad Haris Siddiqui, and Preeti Bajpai. "Anticancer and apoptosis-inducing effects of curcumin against gall bladder carcinoma." International Journal of Research in Pharmaceutical Sciences 9, no. 1 (2018): 68. http://dx.doi.org/10.26452/ijrps.v9i1.1176.

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Curcumin, the primary bioactive component isolated from turmeric, has been shown to possess variety of biologic functions including anti-cancer activity. However, meticulous mechanism of the curcumin in gall bladder cancer has not been explored yet. Therefore, in our study, we elucidated the mechanism of the anticancer action of curcumin against human gall bladder cancer cells. It was found that the curcumin treated GBC cells decreased cell viability in a dose and time-dependent manner. Nuclear condensation, Annexin V-FITC/PI positive cells, and caspase-3 activation confirmed the apoptotic ind

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Pathak, Tarali, Jagannath Dev Sharma, Anupam Sarma, Abhijit Talukdar, and Amal C. Kataki. "Xanthogranulomatous cholecystitis - Mimicking carcinoma gall bladder." IP Journal of Diagnostic Pathology and Oncology 7, no. 2 (2022): 133–36. http://dx.doi.org/10.18231/j.jdpo.2022.032.

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Xanthogranulomatous cholecystitis (XGC)- a rare pathological entity of gall bladder, is characterized by marked inflammatory infiltrates of macrophages and foam cells with proliferative fibrosis of the gall bladder wall. Although it is a benign condition, its radiological picture and intra operative findings mimic gall bladder carcinoma- leading to misdiagnosis in most cases. We report a case of XGC in a middle-aged lady who presented with a lump in right hypochondrium. Computed Tomography (CT) scans of the abdomen was inconclusive for her. A CT-guided Fine Needle Aspiration Cytology (FNAC) wa

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Das, Biswajyoti, Rajesh Pasricha, Deepa Joseph, et al. "Synchronous dual malignancy: a rare case report of carcinoma breast with carcinoma gall bladder." International Journal of Research in Medical Sciences 8, no. 11 (2020): 4140. http://dx.doi.org/10.18203/2320-6012.ijrms20204921.

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Incidence of multiple primary cancers is reported to be between 0.18% to 17.2% in various studies. Occurrence of breast and gall bladder malignancy as synchronous malignancy is very rare. We are reporting one of such rare case. Our patient, a 64 years old lady had a unique presentation. She underwent laparoscopic cholecystectomy for a clinical diagnosis of cholelithiasis. Histopathology turned out to be adenocarcinoma of the gall bladder (Stage II A). A clinical examination done at the time of presentation to our institute revealed suspicious thickening of the skin of the left breast and a sub

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Bharathi, I. Vijaya, P. Urmila Devi, and A. Bhagya Lakshmi. "Study of cholecystectomy specimens over a period of one year in tertiary care centre." International Journal of Research in Medical Sciences 5, no. 3 (2017): 916. http://dx.doi.org/10.18203/2320-6012.ijrms20170636.

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Background: Gall bladder is among the most common surgically resected organs with various neoplastic and non-neoplastic lesions. Chronic chocystitis is the most commonly encountered lesion in India and worldwide and 78-90% are associated with calculi. Gall bladder cancer constitutes 0.5% to 1.09% including both suspected and incidental diagnosis. The objective of present study was to evaluate the various lesions of Gall bladder and the importance of grossing and histopathological examination of every cholecystectomy specimen in order to diagnose the incidental gall bladder cancer (IGBC).Method

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Singh, Prachi, Faiyaz Ahmad, Shyamoli Dutta, Seema Awasthi, and V. K. Singh. "Spectrum of Benign Histopathological Lesions in Cholecystectomy Specimens." Asian Journal of Medical Research 9, no. 2 (2020): 8–13. http://dx.doi.org/10.47009/ajmr.2020.9.2.pt2.

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Background: The most commonly received specimen in any histopathology laboratory is cholecystectomy specimen. The majority of the cholecystectomies are done for Cholelithiasis. Inflammation may be acute, chronic or acute on chronic. It almost always occurs in association with gallstones, which is responsible for carcinoma and if the diagnosed early prognosis of the carcinoma gall bladder is good. Histopathological examination is therefore a must for diagnosis of early carcinomas. Subjects and Methods: 100 cholecystectomy specimens from patients of all ages were included. All specimens were sub

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Gohain, Dhruba Borpatra, and Sima Malakar. "Ultrasonographic features of Carcinoma gall bladder." International Journal of Biomedical Research 6, no. 10 (2015): 811. http://dx.doi.org/10.7439/ijbr.v6i10.2598.

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Kataria, K., R. Yadav, and V. Seenu. "Sarcomatoid carcinoma of the gall bladder." Journal of Surgical Case Reports 2012, no. 2 (2012): 5. http://dx.doi.org/10.1093/jscr/2012.2.5.

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Abel Wahab, Mohamad, Mohamad El-Hemaly, Aymen El-Nakeeb, et al. "GALL BLADDER CARCINOMA: OUR INSTITUTIONAL EXPERIENCE." Egyptian Journal of Surgery 31, no. 3 (2012): 103–9. http://dx.doi.org/10.21608/ejsur.2012.367256.

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NAGPAL, BM, RK BAJPAI, KJ SINGH, JS PANAYCH, and KK MAUDAR. "CARCINOMA GALL BLADDER-AN UNUSUAL PRESENTATION." Medical Journal Armed Forces India 54, no. 4 (1998): 347–48. http://dx.doi.org/10.1016/s0377-1237(17)30603-2.

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Misra, A., S. Misra, A. Chaturvedi, and P. K. Srivastava. "Orbital metastasis from gall bladder carcinoma." British Journal of Radiology 75, no. 889 (2002): 72–73. http://dx.doi.org/10.1259/bjr.75.889.750072.

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Meghadipa Mandal, Debajyoti Singha Roy, Vandana Maroo, and Sanghamitra Mukherjee. "Incidental precancerous and cancerous neoplasms in routine cholecystectomy specimens – A fascinating series of cases in a tertiary care center." Asian Journal of Medical Sciences 14, no. 12 (2023): 298–304. http://dx.doi.org/10.3126/ajms.v14i12.57723.

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Laparoscopic cholecystectomy is one of the most commonly performed surgeries for benign gall bladder pathologies. Pre-cancerous and malignant gall bladder neoplasms often have overlapping non-specific clinical manifestation in their early stages. Radiological findings are also non-specific in the early stages with the presence of cholelithiasis in a significant proportion of cases. Cholelithiasis is said to be one of the important comorbid risk factors for gall bladder carcinoma (GBC) as a source of constant irritation to biliary mucosa. In such cases, cholecystectomy done for benign indicatio

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Khanduri, Sachin, Aakshit Goyal, Tarim Usmani, et al. "Role of ultrasonography in the diagnosis of gall-bladder carcinoma: A boon for low-resource settings." Asian Journal of Oncology 04, no. 01 (2018): 001–5. http://dx.doi.org/10.4103/asjo.asjo_12_18.

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Abstract Purpose: The present study was done with an aim to evaluate the usefulness of ultrasonography (USG) in early diagnosis of gall-bladder carcinoma for low-resource settings. Materials and Methods: A total of 264 clinically suspicious cases were enrolled in the study. The patients underwent USG followed by computed tomography (CT). Histopathological specimens were obtained from 208 cases. Final diagnosis was confirmed histopathologically/CT. Sensitivity, specificity, positive predictive, and negative predictive values of USG were calculated. Results: A total of 29 cases were confirmed as

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Kulkarni, Aparna M., Esha Devendra Jadhav, and Ravindra V. Ramteke. "Histopathological spectrum of gall bladder lesions." International Journal of Research in Medical Sciences 8, no. 3 (2020): 1056. http://dx.doi.org/10.18203/2320-6012.ijrms20200781.

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Background: Gall bladder diseases are a very common health problem that affects millions of people throughout the world. Cholelithiasis is commonly associated with carcinoma gallbladder. Cholecystectomy is the most commonly performed surgical procedure done for gall bladder disease.Methods: A total of 161 cases of gall bladder lesions were evaluated from January 2017 to December 2018 which were sent to department of pathology. Specimens were fixed in 10% formalin. Appropriate areas were selected from the specimen and grossed, processed, sectioned, stained using haematoxylin and eosin and were

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