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Relevant bibliographies by topics / Cardiac tumours / Dissertations / Theses

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Dissertations / Theses on the topic 'Cardiac tumours'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Renier, Vera. "Primary Cardiac Tumors in The Veneto Region of Italy: epidemiology and surgical pathology study in a 12-years interval." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3423145.

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Background: Primary cardiac tumors represent a rare entity in cardiac surgery but have the potential to cause significant morbidity if not treated in an appropriate and timely manner. The aim of the study was to investigate the incidence, histopathology and survival characteristics of patients who underwent surgical resection in Veneto Region in the time interval 2005-2016. Material and Methods: A Regional Registry of primary cardiac tumors was created from data of 6 Cardiac Surgery Institutions of Veneto Region (Mestre, Treviso, Mirano, Padova, Vicenza and Verona), gathering retrospectively

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2

Neves, Floriane André das. "Estudo de tumores cardíacos caninos." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2017. http://hdl.handle.net/10400.5/14067.

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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Os tumores cardíacos são considerados neoplasias raras no cão. Alguns tumores cardíacos provocam vários sinais clínicos, enquanto que outros são diagnosticados acidentalmente. O hemangiossarcoma (HSA) é o tumor cardíaco primário mais prevalente, seguido pelo quemodectoma, linfoma e carcinoma ectópico da tiroide. Em geral os tumores cardíacos secundários são mais frequentes do que os tumores primários. Determinadas raças de cães têm uma maior prevalência de um certo tipo de tumor quando comparadas com a população em geral. Quanto ao

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3

Edmunds, Nicholas J. "Actions of tumour necrosis factor-α in the rat isolated perfused heart". Thesis, University of Bath, 1998. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284400.

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4

Manthri, Sukesh, Bahaaeldin Youssef, Kanishka Chakraborty, and Devapiran Jaishankar. "The Rarest of the Rare: A Case of Primary Cardiac Osteosarcoma." Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/asrf/2020/presentations/13.

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Most cardiac tumors are metastatic tumors, which are 20–40 times more common than primary tumors of the heart. Most primary tumors of the heart are benign, with atrial myxomas being the most common. Primary cardiac tumors are extremely rare with an incidence of less than 0.1 percent. Virtually all types of sarcomas have been reported in the heart as isolated case reports. We present a rare case of biatrial high-grade osteosarcoma. A fifty-four-year-old Hispanic female presented with shortness of breath and was cyanotic on the exam while visiting Mexico. Due to abnormal chest x-ray, echocardiog

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5

Gleeson, Catherine M. "The molecular genetics of adenocarcinoma of the oesophagus and gastric cardia." Thesis, Queen's University Belfast, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387932.

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6

Rostami, Maryam. "A proposed pathophysiological role for TNFa in obesity induced cardiac hypertrophy." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/70077.

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The a of TNFa in title is the Greek alpha.<br>Thesis (MSc)--University of Stellenbosch, 2002.<br>ENGLISH ABSTRACT: Background: Cardiac hypertrophy is an adaptive process occurring in response to mechanical overload or tissue injury. The stimuli for cardiac hypertrophy are diverse and vary from increased afterload on the heart to cardiac remodeling in response to cytokines. Amongst others, obesity is characterized by excessive body weight resulting in metabolic disorders. This excess body weight necessitates an increased blood and oxygen delivery to the peripheral tissues, which is achiev

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7

AL-Thabhani, Hanaa A. "Steriods Protect Against Doxorubicin-Induced Cytotoxicity in Rat Cardiac Myoblastic H9C2 Cells." VCU Scholars Compass, 2006. http://scholarscompass.vcu.edu/etd_retro/18.

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Doxorubicin is one of the most potent anticancer drugs used in the treatment of wide spectrum of neoplastic diseases including breast, thyroid, colon and liver cancer. However, doxorubicin use is associated with undesirable side effects including cardiomyopathy and congestive heart failure. In the present study we have established that treatment of rat cardiac myoblasts (H9c2 cells) with doxorubicin resulted in H9c2 cell injury in a dose and time dependent manner with almost 50% cell death obtained at 5 μM of doxorubicin treatment for 24 hours. We have selected about 50% cell injury as optimum

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8

Devine, Raymond David. "Tumor Induced Cardiovascular Dysfunction." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1448969937.

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9

Ritchie, Andrew John. "Endocrinology, oncogene and tumour suppressor gene expression in Barrett's oesophagus, oesophageal and gastric cardia carcinoma." Thesis, Queen's University Belfast, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238950.

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10

Monteiro, Fernando Jorge Martins. "Revisão da metastização cardíaca a propósito de dois casos de metástases cardíaca de origem em tumores germinativos do testículo." Master's thesis, Instituto de Ciências Biomédicas Abel Salazar, 2008. http://hdl.handle.net/10216/21044.

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11

Monteiro, Fernando Jorge Martins. "Revisão da metastização cardíaca a propósito de dois casos de metástases cardíaca de origem em tumores germinativos do testículo." Dissertação, Instituto de Ciências Biomédicas Abel Salazar, 2008. http://hdl.handle.net/10216/21044.

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12

Charrier, Thibaud. "Study of the occurrence of multiple iatrogenic events in long-term survivors of childhood cancer." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASR030.

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Le taux de survie à 5 ans des cancers de l'enfant atteint aujourd'hui 80 %. Les survivants à 5 ans de cancer pédiatrique (CCS) ont cependant un risque accru d'occurrence de nombreux évènements. Beaucoup d'études ont été réalisé pour comprendre les liens entre ces évènements iatrogènes et les traitements pédiatriques, et un taux élevé d'évènements iatrogènes multiples a été observé. Cependant, ce taux d'évènements iatrogènes multiples est méconnu. Ce projet de thèse avait pour objectif d'étudier les causes et conséquences de ce taux élevé.La recherche présentée dans cette thèse est basée sur le

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13

Mohan, Vandana. "Computer vision and machine learning methods for the analysis of brain and cardiac imagery." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/39628.

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Medical imagery is increasingly evolving towards higher resolution and throughput. The increasing volume of data and the usage of multiple and often novel imaging modalities necessitates the use of mathematical and computational techniques for quicker, more accurate and more robust analysis of medical imagery. The fields of computer vision and machine learning provide a rich set of techniques that are useful in medical image analysis, in tasks ranging from segmentation to classification and population analysis, notably by integrating the qualitative knowledge of experts in anatomy and the path

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14

Schäfer, Michaela [Verfasser], and Stephan [Akademischer Betreuer] Herzig. "Tumor-borne mediators trigger heart atrophy and alter cardiac metabolism in cancer cachexia / Michaela Schäfer ; Betreuer: Stephan Herzig." Heidelberg : Universitätsbibliothek Heidelberg, 2015. http://d-nb.info/1180607945/34.

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15

Yearley, Jennifer Holmes. "Myocardial Macrophage Phenotypic Variation and Cytokine-Mediated Induction of HIV-Associated Cardiac Disease: A Dissertation." eScholarship@UMMS, 2008. https://escholarship.umassmed.edu/gsbs_diss/355.

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Ventricular dysfunction and dilated cardiomyopathy (DCM) develop among untreated HIV-infected people at much higher rates than among HIV-negative individuals, resulting in significant contributions to morbidity and mortality. Mechanisms underlying development of HIV-associated cardiomyopathy (HIVCM) are as yet poorly understood. The well-characterized simian immunodeficiency virus (SIV) model of HIV infection provides a unique context for HIVCM pathogenesis studies in that SIV-infected rhesus monkeys develop myocardial lesions and contractile dysfunction similar to those described in HIV-infec

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16

Camargo, Alissana Ester Iakmiu. "Redução do estresse oxidativo no músculo cardíaco de ratos com caquexia induzida pelo tumor de Walker-256." Universidade Estadual de Londrina. Centro de Ciências Biológicas. Programa de Pós-Graduação em Patologia Experimental, 2008. http://www.bibliotecadigital.uel.br/document/?code=vtls000128856.

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O desenvolvimento da caquexia em doenças malignas como o câncer manifesta-se pela perda de massa corporal, incluindo atrofia, anorexia, anemia, alteração no metabolismo de carboidratos, lipídios e proteínas. As citocinas, especialmente o fator de necrose tumoral α (TNF-α), participam de forma importante na indução do estresse oxidativo e no aumento da produção de espécies reativas de oxigênio (EROs) pelas mitocôndrias. Os miócitos cardíacos contêm muitas mitocôndrias e estas contribuem em grande proporção pela produção de EROs que são formadas durante a fosforilação oxidativa, reflet

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17

Mascarenhas, Marcello Ávila. "Excessiva atividade de remodelamento ventricular sinaliza limitada resposta terapêutica ao manejo agressivo da insuficiência cardíaca avanaçada." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2005. http://hdl.handle.net/10183/5497.

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Introdução: Níveis de fator de necrose tumoral–alfa (TNF-α), N-peptídeo do pró-colágeno III (PIIINP) e metaloproteinase de matriz –1 (MMP-1), marcadores biológicos de remodelamento ventricular, estão elevados em pacientes com insuficiência cardíaca (IC), talvez refletindo elevadas pressões de enchimento. A correlação destes marcadores com variáveis clínicas e hemodinâmicas permanece pouco compreendida, particularmente no contexto ambulatorial da IC. Objetivo: Avaliar níveis séricos de marcadores biológicos de remodelamento ventricular em pacientes com IC, comparando tratamento guiado por ecoca

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18

Borges, Fernando Henrique. "Relação entre o estresse oxidativo e a caquexia cardíaca em ratos Wistar portadores da forma sólida do tumor de Walker-256." Universidade Estadual de Londrina. Centro de Ciências da Saúde. Programa de Pós-Graduação em Ciências da Saúde, 2013. http://www.bibliotecadigital.uel.br/document/?code=vtls000190064.

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A caquexia do câncer é uma doença caracterizada pela perda progressiva de massa corporal, não envolvendo apenas a musculatura esquelética, mas também a cardíaca. Embora existam relatos de perda de massa muscular cardiaca em ratos portadores de tumor, até o momento existem poucas relações entre estresse oxidativo e caquexia cardiaca. Assim, o presente trabalho objetivou investigar a relação entre estresse oxidativo e ativação de diferentes vias proteolíticas no coração de ratos portadores de tumor de Walker-256. Os animais foram divididos em: animais sem tumor e animais com tumor em 2 diferente

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19

Silva, Miguel Morita Fernandes da. "Marcadores genéticos e inflamatórios na insuficiência cardíaca: o impacto do exercício físico." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-08042016-145939/.

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Introdução: O exercício físico pode reverter o prejuízo funcional causado pela insuficiência cardíaca (IC). No entanto, os mecanismos implicados na melhora funcional e o efeito do exercício em outros biomarcadores de gravidade, incluindo microRNAs e marcadores de inflamação, são apenas parcialmente compreendidos.Objetivos: Avaliar o efeito do exercício nos níveis séricos da adiponectina, interleucina-6 (IL-6), fator de necrose tumoral alfa (TNF-alfa), galectina-3, microRNAs miR-423-5p, -221 e -155 em pacientes com IC. Analisar a associação entre estes biomarcadores e a melhora da capacidade fu

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20

Noel, Vanesa Barbara. "Primary cardiac neoplasms: do effective treatments exist." Thesis, 2015. https://hdl.handle.net/2144/15622.

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Primary cardiac neoplasms (PCNs) represent the rarest form of neoplastic growths worldwide with an incidence ranging from 0.001 - 0.3% in autopsy series (Yu et al., 2014) ("Primary Cardiac Neoplasms," 2014). The rarity of these tumors has contributed to the challenges associated with their diagnosis and treatment ("Primary Cardiac Neoplasms," 2014). Primary heart tumors are generally classified as benign or malignant based on whether or not the tumors cells invade their surrounding tissue. Primary benign heart tumors can be further sub-classified as non-complicated or complicated. Non-complica

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21

De, Gouveia Paulo. "Cardiac Glycosides, a Novel Treatment for Neuroblastoma: Efficacy and Mechanism." Thesis, 2010. http://hdl.handle.net/1807/25547.

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In an attempt to identify agents that specifically target neuroblastoma (NB) tumour-initiating cells (TIC) we performed drug screens using libraries of bioactive compounds. Cardiac glycosides (CGs) were the largest class of drugs identified with antitumour activity. At high CG doses inhibitory effects on the Na+/K+-ATPase induce cardiotoxicity; therefore, CG analogues were designed in an attempt to separate the effects on NB cells from cardiotoxicity. We identified RIDK34 as our lead compound from a structure-activity-relationship analysis (IC50 8 nM). RIDK34 contains a unique oxime group and

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22

Luo, Tsai-Yueh, and 羅彩月. "A Study of Cardiac Function in the Hypercholesterolemia Rabbits and the Development of Therapeutic Radiopharmaceuticals for Hepatic Tumors." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/21396263857239578349.

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博士<br>國立臺灣大學<br>藥理學研究所<br>93<br>Hypercholesterolemia is a risk factor commonly associated with atherosclerosis, coronary artery disease, and myocardial infarction. In order to assess the effect of hypercholesterolemia on cardiac sympathetic nerve function, New Zealand white rabbits were fed a normal diet (control group), or one enriched with 0.5% cholesterol (hypercholesterol group, HC group) for 3 months. Before and after the 3-month diet treatment, we performed serial imaging examinations and analyzed the uptake and washout ratio of 123I-meta-iodobenzylguanidine (123I-MIBG) from the myocardi

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23

Simões, Diogo André da Cruz. "Tumores Cardíacos Primários Benignos: Resultados Cirúrgicos." Master's thesis, 2019. http://hdl.handle.net/10316/89555.

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Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introdução: Os tumores cardíacos primários benignos são uma doença extremamente rara, existindo poucas séries na literatura que os caracterizem. O objetivo deste trabalho foi sintetizar os resultados cirúrgicos e follow-up a longo prazo destes doentes. Métodos: O espaço temporal da análise retrospetiva decorreu entre Janeiro de 1994 e Julho de 2018, durante o qual 137 doentes foram operados a tumores cardíacos primários benignos, correspondendo a 0,5% da cirurgia cardíaca. Foram consultados os processos clí

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24

Rylander, Marissa Nichole Diller K. R. "Design of hyperthermia protocols for inducing cardiac protection and tumor destruction by controlling heat shock protein expression." 2005. http://repositories.lib.utexas.edu/bitstream/handle/2152/2150/rylanderm20701.pdf.

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25

Rylander, Marissa Nichole. "Design of hyperthermia protocols for inducing cardiac protection and tumor destruction by controlling heat shock protein expression." Thesis, 2005. http://hdl.handle.net/2152/2150.

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26

Pan, Chih Shuo, та 潘治碩. "Mechanisms of Tumor Necrosis Factor-α-Induced Expression of Vascular Cell Adhesion Molecule-1 in Human Cardiac Fibroblasts". Thesis, 2013. http://ndltd.ncl.edu.tw/handle/01534746915717592050.

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碩士<br>長庚大學<br>生物醫學研究所<br>101<br>Several factors have been shown to trigger the mechanisms for the pathogenesis of heart diseases. Although these factors concerning about the increased incidence of inflammatory responses in heart diseases are well known, the intracellular signaling mechanisms regulated by these factors are obscure. Several studies have demonstrated that the recruitment and adhesion of circulating polymorphonuclear cells (PMNs) to cardiac fibroblast (CF) play pivotal roles in the initiation and progression of heart dysfunction. This event is mediated through the up-regulation of

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27

Hsu, Wun Hsin, та 許紋欣. "Mechanisms of Tumor Necrosis Factor-α-Induced C-C Motif Chemokine Ligand 20 Expression and Inhibited by Pristimerin or Celastrol in Human Cardiac Fibroblasts". Thesis, 2018. http://ndltd.ncl.edu.tw/handle/en3uzh.

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28

Svatoňová, Anna. "Ischemická tolerance srdcí potkanů adaptovaných na chronickou hypoxii a fyzickou zátěž: úloha TNF-alfa." Doctoral thesis, 2016. http://www.nusl.cz/ntk/nusl-353472.

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Cardiovascular diseases represent the most important health risk factors because they are responsible for more than 50% of total mortality. Among them, the ischemic heart disease is leading cause of mortality. From the whole spectrum of different cardioprotective phenomena we have selected: 1) adaptation to chronic normobaric hypoxia (CNH) as the traditional experimental model in our laboratory area and 2) protective effect of exercise which in recent years represents promising and clinically relevant protective mechanism. The whole thesis is based on two studies. Aim of the first study was to

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29

Awad, Ahmed. "Tumor necrosis factor triggers the expression and activation of matrix metalloproteinases through NADPH-dependent superoxide production." Master's thesis, 2010. http://hdl.handle.net/10048/976.

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Thesis (M.Sc.)--University of Alberta, 2010.<br>A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Master of Science in Physiology. Title from pdf file main screen (viewed on February 16, 2010). Includes bibliographical references.

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