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1

Gooseman, Michael R., and Alessandro Brunelli. "Cardio-Pulmonary Exercise Testing Prior to Major Surgery." Annals of Surgical Oncology 27, no. 10 (2020): 3583–84. http://dx.doi.org/10.1245/s10434-020-08642-z.

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SIMOES, O., C. COTRIM, M. LOUREIRO, et al. "194 Exercise echocardiography and cardio-pulmonary exercise testing for dilated cardiomyopathy assessment." European Journal of Echocardiography 7 (December 2006): S12. http://dx.doi.org/10.1016/s1525-2167(06)60044-9.

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Nicol, M., A. Deney, O. Lairez, et al. "Prognostic value of cardio-pulmonary exercise testing in cardiac amyloidosis." Archives of Cardiovascular Diseases Supplements 13, no. 1 (2021): 28. http://dx.doi.org/10.1016/j.acvdsp.2020.10.094.

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Collier, Shirley. "The Benefits of Pre-Assessment with Cardio-Pulmonary Exercise Testing." Journal of Perioperative Practice 20, no. 5 (2010): 173–76. http://dx.doi.org/10.1177/175045891002000502.

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This article reviews the benefits of pre-assessment with cardio-pulmonary exercise testing (CPX) and the effectiveness of preoperative interventions in high-risk patients undergoing major surgery. Three patient case studies will be presented from local practice, to give examples of how patients' co-morbidity has been improved prior to surgery or how decisions for surgery can be modified as a result of the CPX test.
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Leithauser, Renate M., Matthias Hütler, and Ralph Beneke. "Optimization of Cardio Pulmonary Exercise Testing in Cystic Fibrosis Patients." Medicine & Science in Sports & Exercise 38, Supplement (2006): S361. http://dx.doi.org/10.1249/00005768-200605001-02406.

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6

Domanski, O., Ali Houeijeh, M. Guillaume, et al. "Shunt fraction in Fontan patients: Insights of cardio-pulmonary exercise testing." Archives of Cardiovascular Diseases Supplements 11, no. 1 (2019): 132. http://dx.doi.org/10.1016/j.acvdsp.2018.10.290.

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Niederseer, David, Roman Walser, Christian Schmied, et al. "Effects of a 12-Week Recreational Skiing Program on Cardio-Pulmonary Fitness in the Elderly: Results from the Salzburg Skiing in the Elderly Study (SASES)." International Journal of Environmental Research and Public Health 18, no. 21 (2021): 11378. http://dx.doi.org/10.3390/ijerph182111378.

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Objectives: To investigate whether recreational alpine skiing in the elderly can improve cardio-pulmonary fitness. Design: Randomized controlled study with pre–post repeated measurements. Methods: A total of 48 elderly participants (60–76 years) were randomly assigned to either participate in a 12-week guided recreational skiing program (intervention group, IG, average of 28.5 ± 2.6 skiing days) or to continue a sedentary ski-free lifestyle (control group, CG). Cardio-pulmonary exercise testing (CPET) and pulmonary function testing were performed in both groups before (PRE) and after (POST) th
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Parkes, E., V. Moore, D. Comer, F. Rauf, N. Santana-Vaz, and R. Mukherjee. "P214 Utilisation Of Cardio-pulmonary Exercise Testing (cpet) At An English Acute Hospital." Thorax 69, Suppl 2 (2014): A171. http://dx.doi.org/10.1136/thoraxjnl-2014-206260.343.

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9

Cherneva, Zheina, and Radostina Cherneva. "Autonomic dysfunction, cardio-pulmonary parameters and masked heart failure in non-severe  chronic obstructive pulmonary disease." Bulgarian Cardiology 26, no. (4) (2020): 46–54. https://doi.org/10.3897/bgcardio.26.e58373.

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<strong>Background:</strong> Autonomic dysfunction (AD) and cardio-pulmonary exercise testing (CPET) parameters have been associated with masked heart failure with preserved ejection fraction (HFpEF) in the general population. Their clinical significance for masked HFpEF in chronic obstructive pulmonary disease (COPD) is however elusive. <strong>Aim:</strong> The aim of the study was to determine the prevalence, correlation and clinical significance of AD and CPET with masked HFpEF, in non-severe COPD patients, complaining of exertional dyspnea, without clinically overt cardio-vascular (CV) co
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Satendra, Mishra, Yadav Sunil, K. Bhargava J., Kharadee Rajesh, and Patel Vikas. "To Assess Stratification for Cardiovascular Risk Factor through Cardio Pulmonary Exercise Testing in Young Indian Patients with Cardiac Risk." International Journal of Pharmaceutical and Clinical Research 15, no. 8 (2023): 619–24. https://doi.org/10.5281/zenodo.11491598.

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<strong>Background:</strong>&nbsp;Cardiovascular risk factors are increasingly prevalent in young Indian adults, contributing to the burden of cardiovascular diseases (CVDs). Cardiopulmonary exercise testing (CPET) holds potential as a tool for risk stratification in this population.&nbsp;<strong>Aim and Objective:</strong>&nbsp;To assess the associations between exercise parameters and demographic/physiological factors in young Indian patients with cardiac risk factors.&nbsp;<strong>Materials and Methods:</strong>&nbsp;A prospective cross-sectional study was conducted on 30 young Indian patie
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Kelekhsaev, Petr A., Yurgita R. Varaeva, Oxana A. Kislyak, and Antonina V. Starodubova. "The applicability of cardiopulmonary exercise testing of young obese adults." HERALD of North-Western State Medical University named after I.I. Mechnikov 16, no. 4 (2024): 126–33. https://doi.org/10.17816/mechnikov634273.

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BACKGROUND: Obesity is an independent risk factor for cardiovascular disease. In this regard, the early detection of cardio-vascular disfunction among young adults is an important issue. This problem can be solved by the cardiopulmonary exercise testing. AIM: The aim of this study is to determine the applicability of cardiopulmonary exercise testing to assess the functional cardiovascular state in young and obese adults. MATERIALS AND METHODS: 84 young participants (18–44 years), 39% men, underwent a comprehensive examination including anthropometry, spirometry and cardiopulmonary exercise tes
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12

Davies, S., T. Gatenby, R. Sinclair, A. Batterham, and G. Danjoux. "Can cardio-pulmonary exercise testing predict risk of adverse events following abdominal aortic aneurysm surgery?" European Journal of Anaesthesiology 27 (June 2010): 67–68. http://dx.doi.org/10.1097/00003643-201006121-00215.

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13

Jarvis, Daisy, Amy Dewar, Nicholas Tetlow, Robert Stephens, and Samuel Meyler. "Cardio-pulmonary exercise testing aids chronic obstructive pulmonary disease diagnosis in the perioperative evaluation of patients undergoing radical cystectomy." Graduate Journal of Sports Science, Coaching, Management, & Rehabilitation 1, no. 3 (2024): 31. http://dx.doi.org/10.19164/gjsscmr.v1i3.1513.

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Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung condition distinguished by structural changes and mucus build-up which causes dyspnoea. COPD is universally diagnosed by a spirometry test. A Forced Expiratory Volume in one second (FEV1)/Forced Vital Capacity (FVC) of &lt;0.7, is often used to justify COPD diagnosis (Hopkinson et al., 2019, Brit Med J, 366, l4486). Reliance on spirometry tests alone may only highlight airway obstruction and not identify other consequences of COPD like impaired gas exchange which is implicated in the development of postoperative pulmonary complicat
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Smith, T. B., C. Stonell, S. Purkayastha, and P. Paraskevas. "Cardiopulmonary exercise testing as a risk assessment method in non cardio-pulmonary surgery: a systematic review." Anaesthesia 64, no. 8 (2009): 883–93. http://dx.doi.org/10.1111/j.1365-2044.2009.05983.x.

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15

Konigstein, Maayan, Alessia Azzano, Shmuel Banai, Yan Topilsky, and Stefan Verheye. "CARDIO-PULMONARY EXERCISE TESTING (CPET) IN PATIENTS WITH REFRACTORY ANGINA PECTORIS UNDERGOING CORONARY SINUS REDUCER IMPLANTATION." Journal of the American College of Cardiology 71, no. 11 (2018): A1117. http://dx.doi.org/10.1016/s0735-1097(18)31658-9.

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16

Thing, J. E. R., B. Mukherjee, K. Murphy, H. Tighe, and L. Howard. "P189 Evaluation of the role of cardio-pulmonary exercise testing in the diagnosis of unexplained breathlessness." Thorax 66, Suppl 4 (2011): A144—A145. http://dx.doi.org/10.1136/thoraxjnl-2011-201054c.189.

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17

Jivegård, L. "Commentary on ‘A Systematic Review of the Role of Cardio-pulmonary Exercise Testing in Vascular Surgery’." European Journal of Vascular and Endovascular Surgery 44, no. 1 (2012): 72. http://dx.doi.org/10.1016/j.ejvs.2012.05.002.

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18

Allen, Sophie, Saurav Chakravartty, David Timbrell, et al. "PS02.180: THE ROLE OF CARDIOPULMONARY EXERCISE TESTING IN OESOPHAGO-GASTRIC CANCER SURGERY: EVALUATION OF A SINGLE-CENTRE EXPERIENCE." Diseases of the Esophagus 31, Supplement_1 (2018): 173. http://dx.doi.org/10.1093/dote/doy089.ps02.180.

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Abstract Background Cardiopulmonary exercise testing (CPEX) is an objective measure of functional capacity adapted to predict post-operative morbidity. CPEX may also identify optimisable cardio-respiratory comorbidity, prompting treatment modification or specialist referral. The role of CPEX in patient optimisation before oesophago-gastrectomy is yet to be evaluated. This study aims to assess the utility of CPEX in altering management and optimising patients prior to oesophago-gastrectomy. Methods All patients who underwent pre-operative CPEX testing and two phase oesophago-gastrectomy (Januar
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Komici, Klara, Antonio Bianco, Fabio Perrotta, et al. "Clinical Characteristics, Exercise Capacity and Pulmonary Function in Post-COVID-19 Competitive Athletes." Journal of Clinical Medicine 10, no. 14 (2021): 3053. http://dx.doi.org/10.3390/jcm10143053.

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Background: Limited evidence exists regarding adverse modifications affecting cardiovascular and pulmonary function in physical active adults affected by COVID-19, especially in athletic populations. We aimed to describe the clinical presentation of COVID-19 in a cohort of competitive athletes, as well as spirometry and echocardiography findings and cardio-respiratory performance during exercise. Methods: Twenty-four competitive athletes with COVID-19 were recruited for this study after ending self-isolation and confirmation of negative laboratory results. All athletes underwent clinical evalu
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Satendra, Mishra, Kharadee Rajesh, K. Bhargava J., Yadav Sunil, Patel Vikas, and Asati Aashutosh. "To Evaluate the Associated Factors and Cardio Pulmonary Exercise Testing in Young Indian Patients with Cardiac Risk." International Journal of Toxicological and Pharmacological Research 13, no. 8 (2023): 65–68. https://doi.org/10.5281/zenodo.11096057.

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<strong>Background:</strong>&nbsp;Cardiovascular diseases (CVDs) are increasingly affecting young individuals in India, necessitating a comprehensive evaluation of associated factors and cardiac risk. Cardio-pulmonary exercise testing (CPET) provides valuable insights into cardiovascular fitness and response to physical exertion, making it a crucial tool for assessing cardiac risk in this demographic.&nbsp;<strong>Aims and Objective:</strong>&nbsp;To identify the associated factors and Cardio Pulmonary Exercise testing in young Indian patients with cardiac risk.&nbsp;<strong>Materials and Meth
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21

Bhagwat, Milind, and Kaggere Paramesh. "Cardio-pulmonary exercise testing: An objective approach to pre-operative assessment to define level of perioperative care." Indian Journal of Anaesthesia 54, no. 4 (2010): 286. http://dx.doi.org/10.4103/0019-5049.68369.

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22

Cherneva, Radostina, Stefan Denchev, and Zheyna V. Cherneva. "Autonomic dysfunction, cardio‐pulmonary exercise testing and masked heart failure with preserved ejection fraction in non‐severe chronic obstructive pulmonary disease." Clinical Physiology and Functional Imaging 40, no. 4 (2020): 224–31. http://dx.doi.org/10.1111/cpf.12623.

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23

Mikalački, Milena, Nebojša Čokorilo, and Pedro Jesús Ruiz-Montero. "The effects of a pilates-aerobic program on maximum exercise capacity of adult women." Revista Brasileira de Medicina do Esporte 23, no. 3 (2017): 246–49. http://dx.doi.org/10.1590/1517-869220172303156004.

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ABSTRACT Introduction: Physical exercise such as the Pilates method offers clinical benefits on the aging process. Likewise, physiologic parameters may be improved through aerobic exercise. Methods: In order to compare the differences of a Pilates-Aerobic intervention program on physiologic parameters such as the maximum heart rate (HRmax), relative maximal oxygen consumption (relative VO2max) and absolute (absolute VOmax), maximum heart rate during maximal oxygen consumption (VO2max-HRmax), maximum minute volume (VE) and forced vital capacity (FVC), a total of 64 adult women (active group = 4
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Tennant, Ellie, and Mark Faghy. "Investigating the relationship between minute ventilation and metabolic contribution in long COVID: A retrospective cohort study utilizing cardiopulmonary exercise testing." Graduate Journal of Sports Science, Coaching, Management, & Rehabilitation 1, no. 3 (2024): 47. http://dx.doi.org/10.19164/gjsscmr.v1i3.1530.

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Long COVID (LC) presents as a complex and debilitating condition characterized by persistent, episodic symptoms that significantly impact individuals' quality of life and functional capabilities (Brown et al., 2021, BMJ Glob Health, 6). There are several hypotheses for the underlying pathophysiology and mechanisms of long COVIDs nature. This study aims to explore the association between minute ventilation and metabolic contribution in individuals experiencing long-term COVID-19 symptoms. Utilising cardiopulmonary exercise testing (CPET), acknowledged as precise, non-invasive prognostic tools,
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Kalinov, Roman, Blagoi Marinov, Ludmila Vladimirova-Kitova, Vladimir Hodzhev, and Stefan Kostianev. "The six-minute walk test – a reliable test for detection of exercise-related desaturation in patients with chronic obstructive pulmonary disease." Folia Medica 65, no. 4 (2023): 569–76. http://dx.doi.org/10.3897/folmed.65.e85983.

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Introduction: Exercise-induced desaturation is common in patients with moderate to severe chronic obstructive pulmonary disease (COPD). It provides additional information about physical capacity and disease evolution, and it is an important predictor of mortality. Aim: To compare the six-minute walk test (6MWT) and the cardio-pulmonary exercise test (CPET) as methods for detection of desaturation in COPD patients. To explore the relationship between exercise-related desaturation, symptom questionnaires (mMRC, CAT, and SGRQ), pulmonary function testing (PFT), and blood-gas analysis. Patients an
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Kampouras, Asterios, Elpis Hatziagorou, Vasiliki Avramidou, Vasiliki Georgopoulou, Fotios Kirvassilis, and John Tsanakas. "Does Pseudomonas aeruginosa Colonization Affect Exercise Capacity in CF?" Pulmonary Medicine 2019 (December 17, 2019): 1–5. http://dx.doi.org/10.1155/2019/3786245.

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Introduction. Cardio-Pulmonary Exercise Testing (CPET) has been recognized as a valuable method in assessing disease burden and exercise capacity among CF patients. Aim. To evaluate whether Pseudomonas aeruginosa colonization status affects Exercise Capacity, LCI and High-Resolution Computed Tomography (HRCT) indices among patients with CF; to check if Pseudomonas colonization can predict exercise intolerance. Subjects. Seventy-eight (78) children and adults with CF (31 males) mean (range) age 17.08 (6.75; 24.25) performed spirometry, Multiple Breath Washout (MBW) and CPET along with HRCT on t
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Cherneva, Zheina, Dinko Valev, Vania Youroukova, and Radostina Cherneva. "Left ventricular diastolic dysfunction in non-severe chronic obstructive pulmonary disease – a step forward in cardiovascular comorbidome." PLOS ONE 16, no. 3 (2021): e0247940. http://dx.doi.org/10.1371/journal.pone.0247940.

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Chronic obstructive pulmonary disease (COPD) augments the likelihood of having left ventricular diastolic dysfunction (LVDD)–precursor of heart failure with preserved ejection fraction (HFpEF). LVDD shares overlapping symptomatology (cough and dyspnea) with COPD. Stress induced LVDD is indicative of masked HFpEF. Our aim was to evaluate the predictive value of inflammatory, oxidative stress, cardio-pulmonary and echocardiographic parameters at rest for the diagnosis of stress LVDD in non-severe COPD patients, who complain of exertional dyspnea and are free of overt cardiovascular diseases. A t
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Moser, Othmar, Max L. Eckstein, Olivia McCarthy, et al. "Heart rate dynamics during cardio-pulmonary exercise testing are associated with glycemic control in individuals with type 1 diabetes." PLOS ONE 13, no. 4 (2018): e0194750. http://dx.doi.org/10.1371/journal.pone.0194750.

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Pichurko, Bohdan M., J. Trosell, D. Luneack, C. Rubner, and A. Pichurko. "THE VALUE OF CARDIO-PULMONARY EXERCISE TESTING (CPET) IN THE DETECTION OF CARDIAC DISEASE IN RESPIRATORY IMPAIRED (RI) PATIENTS." Chest 128, no. 4 (2005): 362S. http://dx.doi.org/10.1378/chest.128.4_meetingabstracts.362s-a.

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Salvi, Rosario, Ilernando Meoli, Antonio Cennamo, et al. "Preoperative high-intensity training in frail old patients undergoing pulmonary resection for NSCLC." Open Medicine 11, no. 1 (2016): 443–48. http://dx.doi.org/10.1515/med-2016-0079.

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AbstractThoracic surgery remains the better therapeutic option for non-small cell lung cancer patients that are diagnosed in early stage disease. Preoperative lung function assessment includes respiratory function tests (RFT) and cardio-pulmonary exercise testing (CPET). Vo2 peak, FEV1 and DLCO as well as recognition of performance status, presence of co-morbidities, frailty indexes, and age predict the potential impact of surgical resection on patient health status and survival risk. In this study we have retrospectively assessed the benefit of a high-intensity preoperative pulmonary rehabili
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Nishkumay, Olga I., Oksana I. Rokyta, Illia A. Kordubailo, et al. "Risk Stratification in Patients with Coronary Artery Disease: Timeliness of Invasive Interventions." Ukrainian Journal of Cardiovascular Surgery 30, no. 4 (2022): 26–32. http://dx.doi.org/10.30702/ujcvs/22.30(04)/nr046-2632.

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Coronary artery disease (CAD) remains a top cause of morbidity and mortality nowadays. Current guidelines are used to deϐine timely diagnostic and management strategies for a patient with new angina symptom. According to the guidelines, the main purpose is assessment of the pretest probability of obstructive CAD. Exercise electrocardiography is the most accessible methodwith 85-90% speciϐicity and 45-50% sensitivity. Cardiopulmonary exercise testing (CPET) with concomitant monitoring of electrocardiogram, heart rate and blood pressure, expired gas analysis has become widespread among different
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Young, R., S. Howard, C. Bridges, et al. "P445 A marathon not a sprint: Establishing a physiotherapist led cystic fibrosis specific Cardio Pulmonary Exercise Testing (CPET) service for Wales." Journal of Cystic Fibrosis 22 (June 2023): S199. http://dx.doi.org/10.1016/s1569-1993(23)00813-5.

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33

Makuloluwa, Thamasi R. "Scope of Cardio-Pulmonary Exercise Testing (CPET)&nbsp;In Perioperative Risk-Stratification and&nbsp;Shared Decision-Making&nbsp;." Sri Lankan Journal of Anaesthesiology 33, no. 02 (2025): 133–35. https://doi.org/10.4038/slja.v33i02.9651.

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Kowalczyk-Jurgiel, Sylwia, Anke Scheel-Sailer, Angela Frotzler, Joëlle Leonie Flueck, Anna Jegier, and Claudio Perret. "Exercise Capacity, Functioning and Quality of Life 12 Weeks after Traumatic Thoracic Spinal Cord Injury." Ortopedia Traumatologia Rehabilitacja 23, no. 4 (2021): 257–62. http://dx.doi.org/10.5604/01.3001.0015.2362.

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Background. A spinal cord injury (SCI) leads to patho-physiological changes that can affect physical and psychological performance. The aim of this observational study was to evaluate the relationship between exercise capacity, functioning and quality of life in patients 12 weeks after traumatic paraplegia participating in early rehabilitation. Material and methods. 13 patients participated in this study and performed cardio-pulmonary exercise testing (CPET) on an arm-crank ergometer to determine peak exercise capacity (VO2peak). Data from the spinal cord independence measure (SCIM) were used
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Priel, Eldar, Nermin Diab, Matthew Patel, et al. "The added value of haemoglobin to height, age, and sex to predict DLCO in subjects with preserved exercise capacity." PLOS ONE 18, no. 8 (2023): e0289540. http://dx.doi.org/10.1371/journal.pone.0289540.

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Background The single breath diffusion capacity for carbon monoxide (DLCO) captures several aspects of the role of the lung in meeting the metabolic demands of the body. The magnitude of the independent contributors to the DLCO is unknown. The aim of this study was to investigate the factors that independently contribute to the DLCO. Objectives The objective was to investigate the impact of height, age, sex and haemoglobin on DLCO, alveolar volume (VA) and carbon monoxide transfer coefficient (KCO). Methods Study participants were pre-screened based on normal exercise capacity achieved during
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Hennessy, Dr Declan, Dr Matthew Wallen, Dr Stephen Brown, et al. "THE PROTECT TRIAL - PREOPERATIVE EXERCISE THERAPY FOR PATIENTS WITH CANCER: A PILOT RANDOMISED-CONTROLLED TRIAL." Journal of Clinical Exercise Physiology 13, s2 (2024): 332. http://dx.doi.org/10.31189/2165-7629-13-s2.332.

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INTRODUCTION &amp; AIMS Prehabilitation exercise is a promising strategy in oncology to optimise pre-operative cardiorespiratory fitness (CRF), which could reduce post-operative complications, mortality and enhance quality of life. This trial aimed to investigate the safety, feasibility, and effects of an aerobic prehabilitation exercise program in breast, colorectal, and prostate cancer patients. Primary outcomes were serious adverse events (SAE), adverse events (AE), participant adherence and compliance. Secondary outcomes were CRF variables and patient well-being. METHODS A CONSORT-complian
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Young, R., S. Howard, C. Bridges, et al. "P443 A sprint not a marathon: initial outcomes from a physiotherapist-led specialist cystic fibrosis (CF) Cardio-Pulmonary Exercise Testing (CPET) service for Wales." Journal of Cystic Fibrosis 22 (June 2023): S198. http://dx.doi.org/10.1016/s1569-1993(23)00811-1.

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Frese, Falko, Philipp Seipp, Susanne Hupfer, Peter Bärtsch, and Birgit Friedmann-Bette. "Insufficient control of exercise intensity by heart rate monitoring in cardiac patients." European Journal of Preventive Cardiology 19, no. 3 (2011): 436–43. http://dx.doi.org/10.1177/1741826711406832.

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Objectives: To test the reliability of heart rate (HR) recommendations for cardiac rehabilitation training obtained from different treadmill tests. Background: For training in cardiac rehabilitation, HR recommendations are derived from cardio-pulmonary tests. Exercise intensity is often controlled through self-monitoring HR by the cardiac patients. Design: Non-randomized clinical trial. Methods: 25 patients of a cardiac sports group (six women, 19 men, age 68.3 ± 5 years, height 171 ± 10 cm, weight 82 ± 12.8 kg) performed a stepwise increasing treadmill test according to a modified Stanford pr
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van Sluis, Klaske E., Anne F. Kornman, Wim G. Groen, et al. "Expiratory Muscle Strength Training in patients After Total Laryngectomy; A Feasibility Pilot Study." Annals of Otology, Rhinology & Laryngology 129, no. 12 (2020): 1186–94. http://dx.doi.org/10.1177/0003489420931889.

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Objectives: Expiratory muscle strength training (EMST) is a threshold based device-driven treatment for improving expiratory pressure. EMST proved to be effective in different patient groups to improve cough function. To date, EMST has not been tested in the total laryngectomy population (TL). Methods: This prospective, randomized case-series study examined feasibility, safety, and compliance of EMST in a group of TL participants and its effects on pulmonary function, physical exertion, fatigue, and vocal functioning. Ten TL participants were included in the study to perform a 4 till 8 weeks o
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Gasser, Benedikt, Walter O. Frey, Paola Valdivieso, Johannes Scherr, Jörg Spörri, and Martin Flück. "Association of Gene Variants with Seasonal Variation in Muscle Strength and Aerobic Capacity in Elite Skiers." Genes 14, no. 6 (2023): 1165. http://dx.doi.org/10.3390/genes14061165.

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Background: The training of elite skiers follows a systematic seasonal periodization with a preparation period, when anaerobic muscle strength, aerobic capacity, and cardio-metabolic recovery are specifically conditioned to provide extra capacity for developing ski-specific physical fitness in the subsequent competition period. We hypothesized that periodization-induced alterations in muscle and metabolic performance demonstrate important variability, which in part is explained by gene-associated factors in association with sex and age. Methods: A total of 34 elite skiers (20.4 ± 3.1 years, 19
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Cherneva, Zheyna, and Radostina Cherneva. "Echocardiographic predictors for stress induced right ventricular diastolic dysfunction in non-severe chronic obstructive pulmonary disease." Bulgarian Cardiology 26, no. 3 (2020): 65–73. http://dx.doi.org/10.3897/bgcardio.26.e53040.

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Background: Pulmonary vasculopathy, right heart structural and functional abnormalities occur even in normoxemic chronic obstructive pulmonary disease patients. Despite of being associated with functional limitation, exacerbations and disease progression, their detection and proper management is still delayed. Aim: Our aim was to establish the frequency of stress induced right ventricular diastolic dysfunction (RVDD) in non-severe COPD patients, free of clinically overt cardiovascular diseases (ischaemic heart disease, heart failure, uncontrolled arterial hypertension), who complain of exertio
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Cherneva, Zheyna, and Radostina Cherneva. "Echocardiographic predictors for stress induced right ventricular diastolic dysfunction in non-severe chronic obstructive pulmonary disease." Bulgarian Cardiology 26, no. (3) (2020): 65–73. https://doi.org/10.3897/bgcardio.26.e53040.

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<strong>Background:</strong> Pulmonary vasculopathy, right heart structural and functional abnormalities occur even in normoxemic chronic obstructive pulmonary disease patients. Despite of being associated with functional limitation, exacerbations and disease progression, their detection and proper management is still delayed. Aim: Our aim was to establish the frequency of stress induced right ventricular diastolic dysfunction (RVDD) in non-severe COPD patients, free of clinically overt cardiovascular diseases (ischaemic heart disease, heart failure, uncontrolled arterial hypertension), who co
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Neteča, Jekaterina, Inga Liepiņa, Una Veseta, and Dmitrijs Babarikins. "THE EFFECT OF FRACTIONATED RED BEETROOT JUICE ON PERFORMANCE AND OVERALL HEALTH OF A HIGH-PERFORMANCE ATHLETES." SOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference 2 (July 3, 2023): 624–32. http://dx.doi.org/10.17770/sie2023vol2.7144.

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Over the past 20 years, nitric oxide has become the turning point in athlete physiology and medical research. It has been observed in scientific studies that there are very different protocols for the use of nitrates (red beetroot juice) and different research methodology and results. The most effective solutions for improving the performance of athletes are still being sought. The purpose of this research is to investigate the performance and overall health of a high-performance athlete after consuming fractionated red beetroot juice. The investigation is a one-case study. The respondent is a
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Kim, Young-Joo, and Kyoung-Min Park. "Possible Mechanisms for Adverse Cardiac Events Caused by Exercise-Induced Hypertension in Long-Distance Middle-Aged Runners: A Review." Journal of Clinical Medicine 13, no. 8 (2024): 2184. http://dx.doi.org/10.3390/jcm13082184.

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Sudden cardiac death (SCD) is rare among athletes. However, hypertrophic cardiomyopathy is the leading cause of SCD among those &lt;35 years of age. Meanwhile, coronary artery disease (CAD) is the primary SCD cause among those ≥35 years of age. CAD-induced plaque ruptures are believed to be a significant cause of cardiovascular diseases in middle-aged individuals who participate in extreme long-distance running activities such as marathons. A total of 1970 articles related to EIH were identified using search terms. Out of these, 1946 studies were excluded for reasons such as arterial hypertens
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Finnegan, Sarah L., David J. Dearlove, Peter Morris, et al. "Breathlessness in a virtual world: An experimental paradigm testing how discrepancy between VR visual gradients and pedal resistance during stationary cycling affects breathlessness perception." PLOS ONE 18, no. 4 (2023): e0270721. http://dx.doi.org/10.1371/journal.pone.0270721.

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Introduction The sensation of breathlessness is often attributed to perturbations in cardio-pulmonary physiology, leading to changes in afferent signals. New evidence suggests that these signals are interpreted in the light of prior "expectations". A misalignment between afferent signals and expectations may underly unexplained breathlessness. Using a novel immersive virtual reality (VR) exercise paradigm, we investigated whether manipulating an individual’s expectation of effort (determined by a virtual hill gradient) may alter their perception of breathlessness, independent from actual effor
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Laederach-Hofmann, Kurt, Rebecca Roher-Gubeli, Nadine Messerli, and Katharina Meyer. "Comprehensive rehabilitation in chronic heart failure - Better psycho-emotional status related to quality of life, brain natriuretic peptide concentrations, and clinical severity of disease." Clinical & Investigative Medicine 30, no. 2 (2007): 54. http://dx.doi.org/10.25011/cim.v30i2.980.

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Purpose: To evaluate the effects of a comprehensive outpatient rehabilitation program in chronic heart failure (CHF) on quality of life (QoL) in relation to emotional status and clinical severity of disease. &#x0D; &#x0D; Patients and Methods: 25 patients with CHF were included in the 12-week comprehensive rehabilitation program. Initially, and at the end of the program, patients underwent graded cardio-pulmonary exercise testing, echocardiography, and determination of brain natriuretic peptide (BNP) concentration. In addition, they were assessed using: The Minnesota Living with Health Failure
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Cherneva, Radostina, Zheyna Cherneva, Vania Youroukova, et al. "Cardio-Respiratory Fitness and Fatigue in Post-COVID-19 Syndrome—A Three-Year Update." Biomedicines 13, no. 5 (2025): 1097. https://doi.org/10.3390/biomedicines13051097.

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Background: Post-COVID-19 syndrome (PCS) is defined as the persistence of symptoms 3 months after acute SARS-CoV-2 infection. The long-term prevalence and clinical progression of PCS has not been established. Our aim was to investigate the symptoms in PCS patients, explore the degree of physical activity, according to the fatigue severity score, and analyze its association with basic cardio-pulmonary exercise testing (CPET) parameters. Methods: A total of 192 subjects with history of SARSCoV-2 infection were included. They filled in the Chronic Fatigue Syndrome Questionnaire (CFSQ) and were di
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Gellen, Barnabas, Laurent Messonnier, Angele Merlet, et al. "Prospective Controlled Trial on Endurance Exercise Training in Adult Sickle Cell Disease Patients." Blood 130, Suppl_1 (2017): 991. http://dx.doi.org/10.1182/blood.v130.suppl_1.991.991.

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Abstract B Gellen and L Messonnier, and L Feasson and P Bartolucci equally contributed to this work Introduction Sickle cell disease (SCD) is the most common inherited disease worldwide. Because favoring the risk of vaso-occlusive crises (VOC), SCD patients are banned from strenuous exercise. We hypothesized that a well-controlled moderate-intensity endurance exercise training (EET) program could improve SCD patients without provoking VOC. Patients and Methods: Weconducted aprospective, multicenter, controlled study with individually tailored Blood lactate-guided (BL) endurance training on a c
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Kirsten, J., A. Jerg, L. Matits, et al. "Respiratory muscle training with an app-based device improves persistent shortness of breath in patients after SARS-CoV-2 Infection – a randomized controlled trial." Deutsche Zeitschrift für Sportmedizin/German Journal of Sports Medicine 74, no. 5 (2023): 175–82. http://dx.doi.org/10.5960/dzsm.2023.570.

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Background: Post-acute sequelae of SARS-CoV-2 infection (PASC) is defined as persistent or newly experienced symptoms after the disease. Shortness of breath is a common symptom reported by individuals with PASC. Respiratory muscle training (RMT) to strengthen respiratory muscles (e.g diaphragm, intercostal muscles) can improve symptoms in various diseases. The aim of the study therefore was to investigate the effectiveness of RMT for the reduction of PASC-related shortness of breath by a daily home-based app-guided training intervention. Methods: Sixteen patients (age 32.0±16.1 years (Mean±SD)
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Calabria, Elisa, Valentina Muollo, Valentina Cavedon, et al. "Type 2 Diabetes Related Mitochondrial Defects in Peripheral Mononucleated Blood Cells from Overweight Postmenopausal Women." Biomedicines 11, no. 1 (2023): 121. http://dx.doi.org/10.3390/biomedicines11010121.

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Type 2 diabetes (T2D) is a multisystem disease that is the subject of many studies, but the earliest cause of the disease has yet to be elucidated. Mitochondrial impairment has been associated with diabetes in several tissues. To extend the association between T2D and mitochondrial impairment to blood cells, we investigated T2D-related changes in peripheral mononucleated blood cells’ (PBMCs) mitochondrial function in two groups of women (CTRL vs. T2D; mean age: 54.1 ± 3.8 vs. 60.9 ± 4.8; mean BMI 25.6 ± 5.2 vs. 30.0 ± 5), together with a panel of blood biomarkers, anthropometric measurements a
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