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Relevant bibliographies by topics / Cardiopulmonary bypass surgery / Dissertations / Theses

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Dissertations / Theses on the topic 'Cardiopulmonary bypass surgery'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 January 2023

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1

Salameh, Aida, Stefan Dhein, Ingo Dähnert, and Norbert Klein. "Neuroprotective strategies during cardiac surgery with cardiopulmonary bypass." Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-215752.

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Aortocoronary bypass or valve surgery usually require cardiac arrest using cardioplegic solutions. Although, in principle, in a number of cases beating heart surgery (so-called off-pump technique) is possible, aortic or valve surgery or correction of congenital heart diseases mostly require cardiopulmonary arrest. During this condition, the heart-lung machine also named cardiopulmonary bypass (CPB) has to take over the circulation. It is noteworthy that the invention of a machine bypassing the heart and lungs enabled complex cardiac operations, but possible negative effects of the CPB on other

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2

Linden, Matthew D. "The haemostatic defect of cardiopulmonary bypass." University of Western Australia. School of Surgery and Pathology, 2003. http://theses.library.uwa.edu.au/adt-WU2006.0009.

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[Truncated abstract] Cardiac surgery involving cardiopulmonary bypass is a complex procedure that results in significant changes to blood coagulation, fibrinolytic biochemistry, platelet number and function, and the vasculature. These are due to pharmacological agents which are administered, haemodilution and contact of the blood with artificial surfaces. Consequently there are significant risks of thrombosis and haemorrhage associated with this procedure. The research presented in this thesis utilises in vitro, in vivo, and a novel ex vivo model to investigate the nature of the haemostatic de

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3

Collins, J. D. "A study of the liver following cardiopulmonary bypass surgery." Thesis, University of Newcastle Upon Tyne, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241404.

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4

Vassalos, Tony. "End organ effects of paediatric cardiopulmonary bypass." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2385/.

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Despite the scientific, technological and surgical improvements of the past 50 years organ dysfunction following elective paediatric cardiac surgery utilising cardiopulmonary bypass continues to account for increased complications, often leading to a protracted course in hospital with a longer stay in intensive care and the potential for irreversible organ damage long term. Furthermore, paediatric cardiac surgeons are routinely undertaking more complex operations with a shift from palliation to early correction. This has resulted in younger children being subjected to longer periods on the byp

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5

Velissaris, Theodore. "Splanchnic injury during coronary surgery with and without cardiopulmonary bypass." Thesis, University of Southampton, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439379.

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6

Flannery, Fionnula Rose. "Neuropsychological outcomes in older adults after surgery with cardiopulmonary bypass." Thesis, University of Sussex, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432425.

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7

Rice, Cynthia K. "Design of a patient monitoring system for cardiopulmonary bypass surgery." Thesis, Virginia Polytechnic Institute and State University, 1989. http://hdl.handle.net/10919/50081.

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A patient monitoring system for cardiopulmonary bypass surgery has been developed. This monitoring system uses a SWAN 286-10 computer (fully IBM PC/AT compatible) and a DT280l-A Input/Output board to monitor seven surgical parameters. This system monitors six temperatures, the hemoglobin content, the arterial oxygen saturation, the venous oxygen saturation, the oxygen consumption, and the blood flow rate through the cardiopulmonary bypass circuit. Additionally, there are three individual timers available. Details and the evaluation of the hardware and software design of this monitoring s

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8

Koning, Nick Julius. "Protection of the microcirculation during cardiac surgery with cardiopulmonary bypass." Thesis, Angers, 2017. http://www.theses.fr/2017ANGE0073/document.

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La chirurgie cardiaque sous circulation extra-corporelle conduit à une altération de la perfusion de la microcirculation, qui peut contribuer de façon importante à la dysfonction d’organe postopératoire. Cette thèse rassemble des études cliniques et animales, dont le but était d’investiguer les mécanismes expliquant la dysfonction microcirculatoire en chirurgie cardiaque sous circulation extra-corporelle. En outre nous avons eu pour but d’évaluer deux stratégies thérapeutiques pour la préservation de la perfusion microcirculatoire au cours de la circulation extracorporelle : l’utilisation d’un

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9

Ray, Michael John. "Causes and prevention of excessive bleeding after cardiopulmonary bypass surgery." Thesis, Queensland University of Technology, 1997.

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10

Parratt, Rachel Nalini. "Monocyte activation of coagulation by cardiopulmonary bypass CPB circuits." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312851.

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11

Sheppard, Stuart Vincent. "Leucocyte filtration and cardiac surgery." Thesis, University of Portsmouth, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.310490.

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12

Ofoegbu, Chimu K. P. "Outcomes of "off-pump" coronary artery bypass grafting in a developing country : advantages over coronary artery bypass grafting on cardiopulmonary bypass." Master's thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/11432.

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Includes abstract.<br>Includes bibliographic references (leaves 53-62).<br>Off-pump coronary artery bypass grafting (OPCAB) was developed to avoid the deleterious effects of CPB. Current literature reveals some peri-operative advantages of OPCAB, with few studies detailing these in Africa. We review our institutional experience with both approaches in higher risk patients to determine pre-operative characteristics, short and mid-term outcomes in a developing country.

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13

Svenmarker, Staffan. "Heparin coating and cardiotomy suction in cardiopulmonary bypass." Doctoral thesis, Umeå : Univ, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-134.

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14

Li, Jia. "Oxygen consumption and oxygen delivery in children after cardiopulmonary bypass surgery." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406548.

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15

Whitbourne, Peta Gaye. "Changes in the clotting viscoelasticity caused by cardiopulmonary bypass (CPB) surgery." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/50547.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1998.<br>Includes bibliographical references (leaves 63-66).<br>One to three percent of the Open Heart Surgery procedures have abnormal bleeding due to acquired platelet dysfunction. Standard clotting tests to determine the cause of bleeding usually take between 25 and 60 minutes to get results. This time frame is not useful for deciding what type of treatment to give to a patient. More importantly, the standard clotting tests is they cannot determine platelet function. The Thrombo-Visco Elastogram (TVE) is

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16

Vedin, Jenny. "Coronary artery bypass surgery without extracorporeal circulation /." Stockholm, 2005. http://diss.kib.ki.se/2006/91-7140-507-0/.

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17

Rajakaruna, Chanaka. "Splanchnic organ function and glucose metabolism during coronary artery bypass surgery with or without cardiopulmonary bypass." Thesis, University of Bristol, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492604.

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Methods: Patients were randomised to off-pump coronary artery bypass grafting (OPCAB) or conventional coronary artery bypass grafting with cardiopulmonary bypass (CABG-CPB). Small intestine function was assessed by differential four sugars (0=methyl-D-glucose, D-xylose, L-rhamnose, and Lactulose) permeability and absorption tests before surgery, at day 1 and day 5 post-surgery. Liver function was assessed before and at the end of surgery by monoethylglycinexyhdide (MEGX)/Iidocaine ratios after injection of 1 mg/kg bolus of lidocaine and by serial measurements of transaminases (AST and ALT), bi

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18

Svoren, E. M. "Genetic regulation of the host response to cardiac surgery and cardiopulmonary bypass." Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/31868.

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There is significant variation between individual patients in the magnitude and pattern of their systemic response to cardiac surgery. Poor outcomes in these patients have been associated with a dysfunctional host response. This thesis seeks to define such variability at the level of gene expression by sequential analysis of transcription before and after surgery for a low risk group of patients undergoing elective cardiac surgery and cardiopulmonary bypass (CPB) patients using expression microarray profiling. To that aim, we analysed sequential global gene expression patterns in circulating p

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19

Raymond, Paul Douglas. "Haemostatic activation and its relationship to neuropsychological changes following cardiopulmonary bypass surgery." Thesis, Queensland University of Technology, 2006. https://eprints.qut.edu.au/16405/1/Paul_Raymond_Thesis.pdf.

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Neuropsychological impairment following cardiopulmonary bypass (CPB) remains a serious consequence of otherwise successful surgery. The incidence of neuropsychological decline is poorly understood due to varied measurement intervals, and perhaps more importantly the use of unreliable detection and classification methods. The reported incidence varies considerably, ranging anywhere from 30% to 90% of subjects. While the nature of this impairment has not been fully elucidated, recent evidence suggests that microembolism during surgery may be the principal causative agent of postoperative cerebra

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Raymond, Paul Douglas. "Haemostatic activation and its relationship to neuropsychological changes following cardiopulmonary bypass surgery." Queensland University of Technology, 2006. http://eprints.qut.edu.au/16405/.

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Neuropsychological impairment following cardiopulmonary bypass (CPB) remains a serious consequence of otherwise successful surgery. The incidence of neuropsychological decline is poorly understood due to varied measurement intervals, and perhaps more importantly the use of unreliable detection and classification methods. The reported incidence varies considerably, ranging anywhere from 30% to 90% of subjects. While the nature of this impairment has not been fully elucidated, recent evidence suggests that microembolism during surgery may be the principal causative agent of postoperative cerebra

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21

Percy, Charles L. "Predicting excess bleeding due to haemostatic failure following cardiac surgery requiring cardiopulmonary bypass." Thesis, Cardiff University, 2015. http://orca.cf.ac.uk/76453/.

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Bleeding following cardiac surgery requiring cardiopulmonary bypass (CPB) is associated with increased morbidity. Identification of patients at increased risk of bleeding might allow intervention to prevent bleeding developing. In this thesis, clotting factors, anticoagulants and calibrated automated thrombin generation were investigated as potential methods for identifying such patients. Post-CPB FXIII, fibrinogen and platelet count were significantly lower in those who bleed more than 2 mL/kg/hr for two consecutive hours and in those who bleed in excess of 1 litre at 24 hours. ROC analysis d

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22

Igreja, S. "The influence of mannose-binding lectin polymorphisms in children undergoing cardiopulmonary bypass surgery." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1445938/.

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Genetic factors may influence the outcome from surgery. Mannose-Binding lectin (MBL) is an important factor in innate immune defense. MBL gene polymorphisms result in deficiency of the encoded protein and increase susceptibility to infection. The objective of this study was to investigate the relationship between MBL-2 exon 1 polymorphisms and outcome of children after cardiopulmonary bypass (CPB) surgery. Two hundred and forty four patients were recruited to this study. Patient's MBL-2 genotype was determined and compared with respect to sepsis development, length of stay in intensive care an

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23

Varghese, David. "Perioperative organ dysfunction in patients undergoing coronary artery bypass grafting either with cardiopulmonary bypass and cardioplegic arrest or without." Thesis, University of Southampton, 2010. https://eprints.soton.ac.uk/364928/.

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24

El-Habbal, Magdi Hassan Ali. "Inflammatory changes during cardiopulmonary bypass surgery and their modulation by modified ultrafiltration in children." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285492.

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25

Pursch, Lindsay Jane. "The short-term effects of off-pump cardiopulmonary bypass graft surgery on cognitive performance." Master's thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/10772.

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Includes bibliographical references (leaves 56-67).<br>Postoperative neurocognitive impairment has been associated with coronary artery bypass graft surgery (CABG). This study investigates the short-term effects of off-pump cardiopulmonary bypass graft surgery (OPCAB) on cognitive performance, as a possible safer alternative in the treatment of coronary artery disease. This research forms part of a larger study in which, in addition to the OPCAB procedure, the cognitive effects of CABG surgery and percutaneous transluminal coronary angioplasty with intra-coronary stenting are assessed. 36 part

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26

Taggart, David Paul. "The effects of a platelet activating factor antagonist on the respiratory, myocardial and cerebral consequences of cardiopulmonary bypass and further observations on cardiac surgery without cardiopulmonary bypass." Thesis, University of Strathclyde, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248531.

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27

Melley, Daniel Deutsch. "The role of haem release in the systemic inflammatory response to surgery requiring cardiopulmonary bypass." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508722.

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28

Nguyen, Bao-Anh Vu. "Characterisation and modulation of the intracellular inflammatory signalling pathways activated during surgery with cardiopulmonary bypass." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/33259.

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Surgery with cardiopulmonary bypass (CPB) is associated with post-operative complications due to systemic inflammation. However, the intracellular signalling pathways that promote inflammation in cardiac surgery with CPB are uncertain. The studies presented in this thesis were designed to illuminate these molecular mechanisms, thereby informing the development of novel anti-inflammatory strategies. This was addressed through a clinical trial to determine the effects of CPB on inflammatory signalling in leukocytes (Chapter 4). In this study, the induction of reactive oxygen species (ROS) and th

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Yogaratnam, Jeysen Zivan. "The effects of preconditioning coronary artery disease patients with hyperbaric oxygen prior to coronary artery bypass graft surgery & cardiopulmonary bypass." Thesis, University of Hull, 2011. http://hydra.hull.ac.uk/resources/hull:4803.

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IntroductionCoronary artery bypass graft (CABG) is associated with periods of ischaemia and reperfusion, which may lead to myocardial dysfunction. In clinical studies, hyperbaric oxygen (HBO2) treatment following an acute myocardial infarction (AMI), has been shown to limit myocardial injury and improve myocardial function. The primary efficacy objective of this study was to determine if systemically preconditioning coronary artery disease (CAD) patients with HBO2, prior to first time elective on cardiopulmonary bypass (CPB) CABG surgery, leads to a remote preconditioning like effect that is c

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30

Kwiatkowski, David M. "Improved Outcomes with Peritoneal Dialysis vs. Furosemide for Oliguria after Cardiopulmonary Bypass in Infants." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1396523170.

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31

Mokhtari, Amir. "Normoxic versus hyperoxic cardiopulmonary bypass in cyanotic paediatric patients undergoing cardiac surgery : a controlled randomised trial." Thesis, University of Bristol, 2014. http://hdl.handle.net/1983/a47e2f66-31ae-4801-9a73-6af26d6f25a3.

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During the embryonic development of the heart and the greater vessels, some malformations may occur that can result in congenital heart diseases (CHD). The incidence of CHDs is estimated to be between 8 to 10 in 1000 live births. They can be the result of an underlying genetic disorder, be related to environmental factors or a combination of both. CHDs may require corrective cardiac surgery in order to improve life expectancy. Due to clinical advances in the recent years, the survival rate of patients with congenital heart disease has improved significantly and it is estimated that by 2020 the

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Balajadia, Jr Arturo Dillomes, and Jr Arturo Dillomes Balajadia. "Effects of Fresh Frozen Plasma on Post-Op Bleeding in Infants Undergoing Cardiac Surgery with Cardiopulmonary Bypass." Thesis, The University of Arizona, 2016. http://hdl.handle.net/10150/620837.

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Severe congenital heart disease (CHD) is diagnosed in the United States 147.4 times per 100,000 live births, excluding still births and abortions^1. With the advancement of diagnostic methods, prenatal care, and screening modalities, the total CHD birth prevalence has increased substantially^2. In turn, this increases the number of cardiac surgery cases. With the advancement of technology and cardiac surgery, smaller and younger patients are undergoing more complex cardiac procedures that involve cardiopulmonary bypass (CPB). Neonates and infants undergoing CPB are susceptible to adverse effec

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33

Chan, Raquel Pei Chen. "Controle intensivo da glicemia versus convencional: tendência de melhor prognóstico clínico em cirurgia cardíaca." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5152/tde-13102014-112005/.

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O estresse cirúrgico causa hiperglicemia, resultado de modificações endócrinas caracterizadas por diminuição da insulina e aumento simultâneo dos hormônios contra-reguladores. A circulação extracorpórea (CEC) provoca estresse intenso resultando também em hiperglicemia. A atenuação ou tratamento da hiperglicemia no estresse, no período perioperatório, de pacientes traumatizados, sépticos e críticos tem mostrado impacto favorável no prognóstico clínico. O objetivo da pesquisa foi: verificar se o controle intensivo da glicemia (80-120mg/dl) versus glicemia menor que 200mg/dl (convencional), ambos

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Rimpiläinen, R. (Riikka). "Minimized cardiopulmonary bypass in extracorporeal circulation:a clinical and experimental comparison with conventional techniques." Doctoral thesis, Oulun yliopisto, 2011. http://urn.fi/urn:isbn:9789514294310.

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Abstract Cardiac surgery with cardiopulmonary bypass (CPB) results in hemodilution, systemic inflammatory response, activation of coagulation and fibrinolysis, and microembolisation, which may all contribute to postoperative organ dysfunction. As an attempt to attenuate these side effects, the use of minimized cardiopulmonary bypass (MCPB) systems has increased. Compared to conventional CPB (CCPB), they are characterized with reduced artificial surface area and blood-air interface. The goal of these alterations has been to reduce systemic inflammation, preserve coagulation function and minimiz

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35

Grief, Gail. "Disturbance in the control of heart rate during exercise following intracardiac repair : contribution of the cardiopulmonary bypass surgery." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=61106.

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This study was designed therefore, to investigate potential contributions of the cardiopulmonary bypass (CPB) procedure to the chronotropic limitation during exercise in surgically corrected CHD adolescents. Patients were divided into 3 groups: operated ventricular septal defect, where CPB is required (VSDop: n = 15); VSD closed spontaneously, no surgery or CPB required (VSDnop: n = 17); and operated patent ductus arteriosus, where surgery does not require CPB (PDA: n = 20). Fifteen healthy age-matched subjects served as the control group (C). All subjects were submitted to a graded maximal ex

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Philippidis, Pandelis. "The role of the monocyte/macrophage in the resolution of the systemic inflammatory response to cardiopulmonary bypass surgery." Thesis, Imperial College London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.479480.

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37

Appelblad, Micael. "Fat contamination of pericardial suction blood in cardiac surgery : clinical and experimental studies in perspectives of transfusion logistics." Doctoral thesis, Umeå : Kirurgisk och perioperativ vetenskap Surgical and Perioperative Sciences, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-754.

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Mariscalco, Giovanni. "Atrial fibrillation after cardiac surgery : an analysis of risk factors, mechanisms, and survival effects." Doctoral thesis, Umeå universitet, Kirurgi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1798.

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Background: Despite the recent improvements in surgical techniques and postoperative patient care, atrial fibrillation (AF) remains the most frequent complication after cardiac surgery. Although postoperative AF is often regarded as a benign clinical condition, this arrhythmia has significant adverse effects on patient recovery and postoperative survival. Its exact pathophysiology has not yet been elucidated. The present thesis aims to analyze AF risk factors and their interaction, pre-existing histological explanatory alterations of the atrium, the AF impact on postoperative survival and the

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Creagh-Brown, Benedict Charles. "The receptor for advanced glycation end-products (RAGE) and its ligands in systemic inflammation following surgery necessitating cardiopulmonary bypass." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/7057.

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Surgery necessitating cardiopulmonary bypass (snCPB) is associated with systemic inflammation which can be severe. Systemic inflammation is common in the critically ill, is associated with adverse outcome and currently has no specific therapy. Insight into the pathogenesis of systemic inflammation may lead to therapies. The receptor for advanced glycation end-products (RAGE) may represent a novel target for intervention. RAGE is a ubiquitous multi-ligand receptor that is up-regulated in the presence of its ligands. Initially characterised as a receptor for glycated proteins, it is also binds t

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Freitas, Rodrigo Ramos de. "Avaliação de alterações ocasionadas pela circulação extracorpórea em cães: estudo clínico, laboratorial e anátomo-histopatológico do coração e pulmões." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-28092006-193515/.

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A circulação extracorpórea (CEC) é atualmente técnica amplamente utilizada na rotina da cirurgia cardíaca humana. Entretanto, na medicina veterinária, ainda não é utilizada rotineiramente devido a alta mortalidade que ocasiona. O presente experimento utilizou cinco cães machos, SRD, em condições satisfatórias para a realização de pesquisa médica. Esses animais foram submetidos a toracotomia intercostal direita convencional e realizadas as mensurações e coletas padrão pertinentes do experimento (M0). Após isso, os animais foram conectados a máquina de circulação extracorpórea, onde permaneceram

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Junior, Vlander Gomes Costa. "Avaliação da função endotelial microvascular, da rigidez arterial e da resposta inflamatória sistêmica em pacientes submetidos a cirurgia cardíaca com circulação extracorpórea." Universidade do Estado do Rio de Janeiro, 2010. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=2280.

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A Cirurgia de Revascularização do Miocárdio, realizada com o auxílio da Circulação Extracorpórea, está associada a alterações importantes na microcirculação e na produção e circulação de citocinas e marcadores inflamatórios. No presente estudo, foram avaliados 23 pacientes com indicação de Revascularização do Miocárdio, no dia do procedimento e 7 e 28 dias após a cirurgia. A microcirculação cutânea, enquanto reflexo da microcirculação coronariana, foi estudada através da hiperemia térmica e/ ou reativa pós oclusiva e da iontoforese de substâncias vasoativas por mecanismos dependentes e indepen

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Jayaram, Raja. "Effects of peri-operative statin treatment on atrial electrical properties, post-operative atrial fibrillation and in-hospital clinical outcomes in patients undergoing elective cardiac surgery." Thesis, University of Oxford, 2014. https://ora.ox.ac.uk/objects/uuid:224a03c7-30f5-456b-a996-0679591ea6a8.

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Surgical myocardial revascularization remains the standard of care for patients with multi-vessel coronary artery disease. A growing body of evidence indicates that systemic inflammation and myocardial oxidative stress are associated with the development of postoperative atrial fibrillation (POAF) and low cardiac output syndrome in patients undergoing cardiac surgery. Statins have been shown to exert rapid anti-inflammatory and antioxidant effects by inhibiting myocardial NOX2 oxidases and by increasing the bioavailability of nitric oxide (NO). However, whether these so-called pleiotropic effe

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Verdesoto, Rodriguez Maribel Carolina. "Effect of remote ischaemic preconditioning in cardiac dysfunction and end-organ injury following cardiac surgery with cardiopulmonary bypass in children : a translational approach investigating clinical outcome and myocardial molecular biology." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7728/.

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Congenital heart disease (CHD) is the most common birth defect, causing an important rate of morbidity and mortality. Treatment of CHD requires surgical correction in a significant percentage of cases which exposes patients to cardiac and end organ injury. Cardiac surgical procedures often require the utilisation of cardiopulmonary bypass (CPB), a system that replaces heart and lungs function by diverting circulation into an external circuit. The use of CPB can initiate potent inflammatory responses, in addition a proportion of procedures require a period of aortic cross clamp during which the

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Niranjan, Gunaratnam. "Effects of autotransfusion with a cell saver on acute phase response, neutrophil activation, and lung function in patients undergoing coronary surgery with and without cardiopulmonary bypass." Thesis, St George's, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511948.

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45

Koskenkari, J. (Juha). "Myocardial ischemia-reperfusion injury and systemic inflammatory response in high-risk cardiac surgery:a clinical study of the effects of high-dose glucose-insulin treatment and the use of leukocyte-depleting filter." Doctoral thesis, University of Oulu, 2006. http://urn.fi/urn:isbn:9514282094.

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Abstract Cardiac surgery with cardiopulmonary bypass induces the activation of systemic inflammatory response syndrome (SIRS) and results in at least some degree of global myocardial ischemia. Although these responses are usually short-lived, they may lead to serious complications and organ system failures. The present study evaluated the effects of high-dose glucose-insulin (1IU/kg/h) treatment (GIK) administered with the hyperinsulinemic normoglycemic clamp technique and a leukocyte-depleting filter on markers of systemic inflammatory response and myocardial ischemia-reperfusion injury in c

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Ferreira, Fabiana Aparecida Penachi Bosco. "Avaliação das concentrações plasmáticas e da farmacocinética da cefuroxima administrada profilaticamente em pacientes submetidos à revascularização do miocárdio." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/5/5152/tde-01122011-152334/.

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Introdução e Objetivos: A circulação extracorpórea (CEC) pode alterar a cinética de fármacos, inclusive dos antibióticos. O objetivo deste estudo foi avaliar influência da CEC sobre a farmacocinética da cefuroxima e verificar se o esquema posológico proposto: 1, 5g em bolus, seguido por três bolus de 750 mg 6/6 horas por 24 horas, mantém concentrações plasmáticas adequadas em pacientes submetidos à revascularização do miocárdio (RM). Método: Foi realizado estudo prospectivo observacional com grupo controle comparando 10 pacientes submetidos à RM com CEC e 9 pacientes submetidos à RM sem CEC (R

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Veliz, Rodrigo Sanchez. "Efeitos imediatos da circulação extracorpórea sobre o sistema mucociliar." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/5/5152/tde-14062011-153309/.

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INTRODUÇÃO: A circulação extracorpórea (CEC) é um fator etiológico importante para a lesão pulmonar, observada após cirurgia cardíaca. No entanto, o impacto da CEC na função mucociliar respiratória é desconhecido. O objetivo do estudo foi avaliar os efeitos imediatos da CEC sobre o sistema de transporte mucociliar. MÉTODOS: 22 porcos mestiços das raças Large White e Landrace com peso entre 33 a 47 kg alocados nos grupos controle (n = 10) e CEC (n = 12) completaram o estudo. As técnicas de anestesia e ventilação mecânica foram padronizadas. Após a indução da anestesia, foi realizada traqueostom

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Salem, Mostafa [Verfasser], Assad [Akademischer Betreuer] Haneya, and Gunnar [Gutachter] Elke. "Acute kidney injury after ascending aorta and aortic arch replacement surgery with moderate hypothermia, circulatory arrest and cardiopulmonary bypass / Mostafa Ahmed Ali Ahmed Salem ; Gutachter: Gunnar Elke ; Betreuer: Assad Haneya." Kiel : Universitätsbibliothek Kiel, 2020. http://d-nb.info/1205314660/34.

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49

Salem, Mostafa Ahmed Ali Ahmed [Verfasser], Assad [Akademischer Betreuer] Haneya, and Gunnar [Gutachter] Elke. "Acute kidney injury after ascending aorta and aortic arch replacement surgery with moderate hypothermia, circulatory arrest and cardiopulmonary bypass / Mostafa Ahmed Ali Ahmed Salem ; Gutachter: Gunnar Elke ; Betreuer: Assad Haneya." Kiel : Universitätsbibliothek Kiel, 2020. http://d-nb.info/1205314660/34.

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50

Amorim, Celio Gomes de. "Efeitos da filtragem de leucócitos sobre a resposta inflamatória e a função pulmonar de pacientes submetidos à revascularização miocárdica com circulação extracorpórea." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5152/tde-25112014-152216/.

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INTRODUÇÃO E OBJETIVOS: A Circulação extracorpórea (CEC) é associada a ativação leucocitária, resposta inflamatória e disfunção pulmonar. Objetivou-se avaliar os efeitos da filtragem leucocitária sobre a resposta inflamatória e a função pulmonar em indivíduos submetidos à revascularização do miocárdio (RM) com CEC. MÉTODO: Após aprovação pelo Comitê de Ética Institucional e obtenção do consentimento informado dos indivíduos, foi realizado estudo prospectivo randomizado, para comparar indivíduos adultos submetidos à RM com CEC, utilizando-se filtragem leucocitária (n=09) ou filtro standard (n=1

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