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1

Algabbani, Aljoharah, Amani Alqahtani, and Nasser BinDhim. "Prevalence and determinants of non-communicable diseases in Saudi Arabia." Food and Drug Regulatory Science Journal 2, no. 2 (August 4, 2019): 1. http://dx.doi.org/10.32868/rsj.v2i2.29.

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Abstract Background Chronic diseases are considered the leading cause of mortality in Saudi Arabia. With a lack of national health surveillance systems, this study examines chronic disease prevalence and multimorbidity and their associated factors in Saudi Arabia. Methods Data was pooled from two cross-sectional national surveys conducted across the 13 regions of Saudi Arabia between March and July 2018. The study targeted Arabic speakers aged 18 years or older. The presence of chronic diseases was assessed according to self-reported medical diagnoses of chronic conditions. Multimorbidity was assessed based on the reported number of diseases (no condition, at least 1, and ≥ 2 conditions). Factors associated with chronic diseases’ presence were examined using regression analysis. Results Out of the total participants (N= 7,317), the most reported chronic conditions were cardiovascular diseases (15.1%) followed by respiratory diseases (14.16%). The multimorbidity prevalence (≥ 2 chronic conditions) was nearly 5.6% (n= 564). Factors found to be significantly associated with the presence of chronic diseases were age, gender, employment status, marital status, and smoking. The findings showed that those who rated their health as fair or poor were almost three times more likely to be diagnosed with at least one chronic condition (95% CI: 2.21 - 3.56, P <0.001). Conclusions The study found a proportion of Saudis living with chronic diseases and multimorbidity with the highest risk among elderly people. The study findings are useful in building a sustainable health surveillance system and designing effective health policies and interventions to tackle the burden of chronic disease in Saudi Arabia.
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Al-Baghli, NadiraA, AqeelJ AL-Ghamdi, KhalidA Al-Turki, AhmadG El-Zubaier, BaderA Al-Mostafa, FadelA Al-Baghli, and MahmoodM Al-Ameer. "Awareness of cardiovascular disease in eastern Saudi Arabia." Journal of Family and Community Medicine 17, no. 1 (2010): 15. http://dx.doi.org/10.4103/1319-1683.68784.

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Yaqub, B. A., A. R. Shamena, T. M. Kolawole, and P. J. Patel. "Cerebrovascular disease in Saudi Arabia." Stroke 22, no. 9 (September 1991): 1173–76. http://dx.doi.org/10.1161/01.str.22.9.1173.

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Bdeir, B., I. Farah, and T. Conboy. "Managing cardiovascular disease: model of care in Saudi Arabia." European Heart Journal Supplements 16, suppl B (November 1, 2014): B96—B98. http://dx.doi.org/10.1093/eurheartj/suu013.

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Saquib, Nazmus, Mohammed Saddik Zaghloul, AbdulRahman Mazrou, and Juliann Saquib. "Cardiovascular disease research in Saudi Arabia: a bibliometric analysis." Scientometrics 112, no. 1 (April 20, 2017): 111–40. http://dx.doi.org/10.1007/s11192-017-2393-z.

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Alshaikh, Mashael K., Filippos T. Filippidis, Juren P. Baldove, Azeem Majeed, and Salman Rawaf. "Women in Saudi Arabia and the Prevalence of Cardiovascular Risk Factors: A Systematic Review." Journal of Environmental and Public Health 2016 (2016): 1–15. http://dx.doi.org/10.1155/2016/7479357.

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Background. Cardiovascular disease (CVD) is one of the leading causes of death in Saudi Arabia. Saudi women in particular are more susceptible as there are sociocultural restrictions on female physical activities that may lead to high prevalence of CVD risks, especially obesity, and physical inactivity. This study aims to systematically review the published articles related to the prevalence of CVD risk among women in Saudi Arabia. The search strategy covers all published articles that assess the risk factor of CVD in Saudi Arabia from January 2000 to December 2015, using the following sources: Medline, Embase, and PsycINFO. A total of 61 studies were included.Results.Prevalence among Saudi women of smoking ranged from 1.1% to 9.1%, hypertension was 21.8%, diabetes ranged from 9.6% to 27.6%, overweight was 27%, and obesity was 40.23%, and physical inactivity ranged from 53.2% to 98.1%. Hypercholesterolemia prevalence on Saudi women on average was 24.5%, while metabolic syndrome ranged from 13.6% to 40.3%.Conclusion. The prevalence of CVD risk factors is high among women in Saudi Arabia especially in obesity and physical inactivity. Public health authorities must implement solutions from a gender specific aspect to reverse the trend and decrease the prevalence of CVDs among Saudi women.
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Bdair, Izzeddin A. "Assessment of Cardiovascular Diseases Knowledge and Risk Factors Among Adult Population in the South Region of Saudi Arabia." Clinical Nursing Research 31, no. 4 (November 21, 2021): 598–606. http://dx.doi.org/10.1177/10547738211060602.

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Cardiovascular diseases are the main cause of mortality and disability worldwide. This study aimed to assess knowledge of cardiovascular disease and risk factors among the adult population in the south region of Saudi Arabia. A web-based cross-sectional survey of 1,049 participants was completed during August 2021. Data were collected by using 25-item heart disease fact questionnaire. The study population included 526 men (50.1%) and 523 women (49.9%) with a mean age of 36 ± 12 years. The average total knowledge score was 65.7 ± 20.80. The items with the highest knowledge were smoking, overweight, aging, high cholesterol, hypertension, diabetes, and family history. Findings revealed that knowledge regarding cardiovascular diseases is inadequate with a high prevalence of risk factors among the Saudi Arabian population. Healthcare professionals and organizations have a crucial role in raising public awareness regarding health promotion, regular screening, and lifestyles modifications. Interventional studies are needed to investigate the actual magnitude of CVDs and counteract them.
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Almarshad, Feras Mansour, Abdulaziz Abdulrahman Alrashed, Khalid Ibrahim Aljammaz, Ali Mohammed Alduhayshi, and Jaber Saleh Alhadlaq. "Prevalence of Cardiovascular Disease Risk Factors in Shaqra, Saudi Arabia." Egyptian Journal of Hospital Medicine 77, no. 2 (October 1, 2019): 4933–37. http://dx.doi.org/10.21608/ejhm.2019.47603.

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9

Alanazi, M., N. P. Reddy, J. P. Shaik, S. A. Ajaj, A. A. A. Jafari, H. Saeed, Z. Khan, and A. P. Khan. "Association of BRCA2 variants with cardiovascular disease in Saudi Arabia." Genetics and Molecular Research 13, no. 2 (2014): 3876–84. http://dx.doi.org/10.4238/2014.may.16.13.

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10

Alwin Robert, Asirvatham, and Mohamed Abdulaziz Al Dawish. "Microvascular complications among patients with diabetes: An emerging health problem in Saudi Arabia." Diabetes and Vascular Disease Research 16, no. 3 (January 1, 2019): 227–35. http://dx.doi.org/10.1177/1479164118820714.

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Diabetes mellitus, besides disrupting the carbohydrate metabolism process, also induces vascular disease and impacts nearly all the types and sizes of blood vessels. In fact, vascular complications cause majority of the morbidity, hospitalizations and mortality of patients with diabetes mellitus. Retinopathy, nephropathy and neuropathy (microvascular complications) impact hundreds of millions of diabetics and normally target those having long-term or uncontrolled forms of the disease; however, these disorders can also exist at the time of diagnosis or in those yet to be diagnosed. The Kingdom of Saudi Arabia is the biggest country in the Middle East that occupies around four-fifths of the Arabian Peninsula supporting a population of more than 33.3 million people. The prevalence of diabetes mellitus is increasing at an alarming rate in Saudi Arabia. Over 25% of the adult population is suffering and that figure is projected to more than double by 2030. In fact, diabetes mellitus has approximately registered a 10-fold upsurge in the past three decades in Saudi Arabia. However, the prevalence and risk factors of microvascular complications in diabetes mellitus patients have not yet been clearly documented in Saudi Arabia. Hence, in this review, we aim to provide an overview of the microvascular complications among patients with diabetes in Saudi Arabia, utilizing data from the currently available published literature. This is an attempt to facilitate the government and healthcare systems aware of the enormous worth of prevention, early detection and appropriate management of such microvascular complications.
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Alkhunizan, Muath, Abdullah Alkhenizan, and Loay Basudan. "Prevalence of Mild Cognitive Impairment and Dementia in Saudi Arabia: A Community-Based Study." Dementia and Geriatric Cognitive Disorders Extra 8, no. 1 (March 20, 2018): 98–103. http://dx.doi.org/10.1159/000487231.

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Introduction: The age of the population in Saudi Arabia is shifting toward elderly, which can lead to an increased risk of mild cognitive impairment (MCI) and dementia. Objective: The aim of this study is to determine the prevalence of cognitive impairment (MCI and dementia) among elderly patients in a community-based setting in Riyadh, Saudi Arabia. Methods: In this cross-sectional study, we included patients aged 60 years and above who were seen in the Family Medicine Clinics affiliated with King Faisal Specialist Hospital and Research Centre. Patients with delirium, active depression, and patients with a history of severe head trauma in the past 3 months were excluded. Patients were interviewed during their regular visit by a trained physician to collect demographic data and to administer the validated Arabic version of the Montreal Cognitive Assessment (MoCA) test. Results: One hundred seventy-one Saudi patients were recruited based on a calculated sample size for the aim of this study. The mean age of included sample was 67 ± 6 years. The prevalence of cognitive impairment was 45%. The prevalence of MCI was 38.6% and the prevalence of dementia was 6.4%. Age, low level of education, hypertension, and cardiovascular disease were risk factors for cognitive impairment. Conclusion: Prevalence of MCI and dementia in Saudi Arabia using MoCA were in the upper range compared to developed and developing countries. The high rate of risk factors for cognitive impairment in Saudi Arabia is contributing to this finding.
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Sulaiteen, Fahad Mohammad, Ibrahim Abdulaziz Al-Zaagi, Majed Sultan Alenazi, Amani Zaben Alotaibi, Tahani Aali Alghamdi, Anum Yousaf, and Sheraz Ali. "Awareness of Cardiovascular Disease Risk Factors by Community Pharmacists in Saudi Arabia." Healthcare 11, no. 2 (January 4, 2023): 151. http://dx.doi.org/10.3390/healthcare11020151.

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Background: Pharmacists in community settings are recognized as highly accessible healthcare practitioners and demonstrate a crucial role in the primary prevention of cardiovascular disease. Evidence indicates that community pharmacists can make a significant impact on controlling cardiovascular disease risk factors, particularly on hypertension. Objectives: We aimed to assess the knowledge of community pharmacists in Saudi Arabia regarding cardiovascular disease risk factors. Methods: A cross-sectional study involving community pharmacists was conducted. The knowledge of cardiovascular disease risk factors was assessed with the Heart Disease Fact Questionnaire (HDFQ). A web link for an anonymous questionnaire was shared with the licensed community pharmacists in Saudi Arabia using the “Seha” platform of the Ministry of Health. Data analysis was performed with R version 4.0.5. Results: Three hundred seventy-four community pharmacists responded to the questionnaire. Many community pharmacists (94.4%) had satisfactory awareness of cardiovascular disease risk factors. The odds of having satisfactory HDFQ knowledge for community pharmacists seeing more than 20 individuals with diabetes per month were 20 times (AOR = 19.9, 95% CI: 1.73–260, and p = 0.019) more compared to those seeing fewer than 10 individuals with diabetes per month. The age of the community pharmacists and the average number of individuals with diabetes seen per month were found to be factors associated with satisfactory HDFQ knowledge. Conclusion: The practicing pharmacists had a substantial understanding of cardiovascular disease risk factors. In line with counseling and education, the implementation of community pharmacy models for improving the knowledge of pharmacists, particularly the young pharmacists, is needed to effectively assist patients with cardiovascular disease.
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Al Zahrani, H. A. "Arteritis: Experience in Jeddah, Saudi Arabia." Cardiovascular Surgery 1, no. 3 (June 1993): 215–19. http://dx.doi.org/10.1177/096721099300100303.

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Inflammation of the arteries is a difficult condition to diagnose and treat. Eighteen consecutive patients (16 men, two women) with arteritis treated in the vascular surgery department of King Fahad Hospital. Jeddah. Saudi Arabia, over a period of 3 years were reviewed to define the local pattern of the disease. The mean age of the group was 29.2 (range 18–50) years. Buerger's disease was diagnosed in 11 patients and considered to be the most common type of arteritis. Other types of arteritis identified were: non-specific (four patients), infective (one), irradiation (one) and vasculitis secondary to scleroderma (one). The most common finding was severe lower-limb ischaemia from infrapopliteal occlusion. Arteriography carried out in 16 patients showed either occlusion or stenosis of the affected artery. In one patient an associated renal aneurysm was detected. All patients were advised to stop smoking and unilateral or bilateral lumbar sympathectomy undertaken in those with Buerger's disease. By adopting this policy limb salvage was achieved in nine of the 11 patients with Buerger's disease. In addition to these measures, corticosteroids were prescribed for selected cases of arteritis.
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Alamer, Amnah, Syed Mohammed Basheeruddin Asdaq, Mohammad AlYamani, Hussain AlGhadeer, Zahra H. Alnasser, Zainab Aljassim, Maryam Albattat, et al. "Characteristics of mechanically ventilated COVID-19 patients in the Al-Ahsa Region of Saudi Arabia: a retrospective study with survival analysis." Annals of Saudi Medicine 42, no. 3 (May 2022): 165–73. http://dx.doi.org/10.5144/0256-4947.2022.165.

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BACKGROUND: About 5-10% of coronavirus disease 2019 (COVID-19) infected patients require critical care hospitalization and a variety of respiratory support, including invasive mechanical ventilation. Several nationwide studies from Saudi Arabia have identified common comorbidities but none were focused on mechanically ventilated patients in the Al-Ahsa region of Saudi Arabia. OBJECTIVES: Identify characteristics and risk factors for mortality in mechanically ventilated COVID-19 patients. DESIGN: Retrospective chart review SETTING: Two general hospitals in the Al-Ahsa region of Saudi Arabia PATIENTS AND METHODS: We included mechanically ventilated COVID-19 patients (>18 years old) admitted between 1 May and 30 November 2020, in two major general hospitals in the Al-Ahsa region, Saudi Arabia. Descriptive statistics were used to characterize patients. A multivariable Cox proportional hazards (CPH) model was used exploratively to identify hazard ratios (HR) of predictors of mortality. MAIN OUTCOME MEASURES: Patient characteristics, mortality rate, extubation rate, the need for re-intubation and clinical complications during hospitalization. SAMPLE SIZE AND CHARACTERISTICS: 154 mechanically ventilated COVID-19 patients with median (interquartile range) age of 60 (22) years; 65.6% male. RESULTS: Common comorbidities were diabetes (72.2%), hypertension (67%), cardiovascular disease (14.9%) and chronic kidney disease (CKD) (14.3%). In the multivariable CPH model, age >60 years old (HR=1.83, 95% CI 1.2-2.7, P =.002), CKD (1.61, 95% CI 0.9-2.6, P =.062), insulin use (HR=0.65, 95% CI 0.35-.08, P <.001), and use of loop diuretics (HR=0.51, 95% CI 0.4, P =.037) were major predictors of mortality. CONCLUSION: Common diseases in mechanically ventilated COVID-19 patients from the Al-Ahsa region were diabetes, hypertension, other cardiovascular diseases, and CKD in this exploratory analysis. LIMITATIONS: Retrospective, weak CPH model performance. CONFLICTS OF INTEREST: None.
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Al Sayegh, Hassan Ali, Abdulaziz Adel Al Qurini, Abdul Sattar Khan, and Sayed Ibrahim. "Patterns of eating associated with the chronic diseases in Al-Ahsa, Saudi Arabia." International Journal Of Community Medicine And Public Health 4, no. 10 (September 22, 2017): 3517. http://dx.doi.org/10.18203/2394-6040.ijcmph20174213.

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Background: There is increase in the limitation of daily activity of people with chronic diseases. This may be due to multiple factors one of them is the nature of the lifestyle for instance, patterns of eating that the person is following. It is important to sum the dietary behaviors in specific population to see how much is it associated with chronic diseases. Specially, obesity, cardiovascular diseases, diabetes and sickle cell disease which are endemic diseases in Al-Ahsa. Moreover, no studies have been conducted in this area before. It is known that there is increased obesity, cardiovascular and diabetes prevalence in Al-Ahsa. The study aims to see the association between chronic diseases and eating patterns. Methods: Cross sectional study, self-reported questionnaire distributed to the population under supervision of the data collectors in Al-Ahsa, during the summer of 2017. Results: The most prevalent chronic disease is obesity. Then comes hypertension and G6PD. Obesity showed most association with other chronic diseases. Also, eating frozen canned food show associations with obesity, hypertension, G6PD and diabetes. Conclusions: We concluded that there are certain eating behaviors influences some chronic diseases; there should be a focus on these behaviors to prevent the occurrence of these chronic diseases, especially metabolic diseases. Obesity is the primary concern which may facilitate the developing of hypertension, asthma, diabetes, high cholesterol, G6PD, hypothyroidism, hyperthyroidism, diabetes, sickle cell disease and cardiovascular events.
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Almansour, Hadi A., Nouf M. Aloudah, Tariq M. Alhawassi, Alemayehu B. Mekonnen, Kevin McNamara, Betty Chaar, Ines Krass, and Bandana Saini. "Cardiovascular disease risk screening by pharmacists in Saudi Arabia: Feasibility and perspectives." Research in Social and Administrative Pharmacy 14, no. 8 (August 2018): e30. http://dx.doi.org/10.1016/j.sapharm.2018.05.040.

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Robert, Asirvatham Alwin. "Cardiovascular Disease among Patients with Diabetes: The Current Scenario in Saudi Arabia." Current Diabetes Reviews 17, no. 2 (2021): 180–85. http://dx.doi.org/10.2174/18756417mta2kotqcw.

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18

AI-Ghalayini, Kamal W., Mohammed A. Salama, Hadia Bassam Al Mahdi, Sameer Al-Harthi, Wesam A. Alhejily, Mirvat A. Alasnag, Noura O. Tasbhji, Diana A. H. Al-Quwaie, Panos Deloukas, and Sherif Edris. "Identification of Genetic Variants Associated With Myocardial Infarction in Saudi Arabia." Heart Surgery Forum 23, no. 4 (July 23, 2020): E517—E523. http://dx.doi.org/10.1532/hsf.2955.

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The genetic variants associated with various genetic disorders have not been identified decisively in Saudi Arabia. Among these variants, six known for their association with coronary artery disease or myocardial infarction (MI) were studied on Saudi patients. Reference single nucleotide polymorphisms (SNPs) of these variants are rs5174, rs11591147, rs2259816, rs111245230, rs3782886 and rs2259820, referring to genes LRP8, PCSK9, HNF1A, SVEP1, BRAP and HNF1A, respectively. The analysis employed polymerase chain reaction panel coupled with mini-sequencing (SNapShot multiplex system) in order to identify these variants. A total of 100 MI patients and 103 healthy control individuals participated in this study. The six variants (SNPs) were evaluated for the risk of developing MI in the Saudi patients. Analysis of allele frequencies indicated that A allele of rs11591147 variant can be a protective allele, thus, is associated with the decreased risk of MI in Saudi individuals. Rare allele of rs111245230 variant (e.g., C allele) was extremely reduced, while rare allele of rs3782886 variant (e.g., G allele) does not exist in the ethnic signature of the Saudi population. This study elucidates the possible prediction of risk factors associated with severe diseases in Saudi population utilizing SNapShot multiplex system.
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Abdulaziz Balbaid, Eman, Manal Abdulaziz Murad, Hoda Jehad Abousada, Nada Faiez Alshanbari, Rana Abualqasim Kudam, Abdulmajeed Hadi Alanazi, Abdullah Matar Alsulaimi, et al. "PREVALENCE OF PULMONARY HYPERTENSION IN SICKLE CELL ANEMIAI PATIENT IN KSA." International Journal of Advanced Research 8, no. 12 (December 31, 2020): 1183–88. http://dx.doi.org/10.21474/ijar01/12271.

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Introduction: Pulmonary hypertension (PH) is a relatively common and severe complication of SCI and an independent risk factor for mortality. Sickle cell disease is considered one of the most common diseases in the Kingdom of Saudi Arabia. When a healthy disease related to cardiovascular health is highlighted, sickle cell anemia may be the most common and related disease in high pulmonary pressure. In this study, we aimed in this study to determine prevalence of PHTN in SCA patient, and associated risk factors with it. Methodology: This is an analytical cross-sectional study conducted in kingdom of Saudi Arabia (General population, SCA patient and CVD patient), from 29/7/2020 till 15/11/2020. The study was depending on online self-reported questionnaire that included assessing the demographic factors as gender, nationality besides, disease-related information: SCA patient , CVD patient and DM patient. Results: we received 794 responses to our questionnaire where 93.5 % of them were Saudi Arabian. The prevalence of sickle cell anemia is 8.8 %. Male represented 29.8 % of patients while female represented 52.2 % of patients. In SCA patients, the prevalence of PHTN was 31.8 %. Moreover, it was found that having cardiac disease is considered a risk factor for developing PHTN where 37.7 % of patients having cardiac disease had PHTN compared with 6.2 % of health patients (OD: 9.16, 95 % CI: 5.5479 to 15.13, P=0.000) while diabetes mellitus increase risk for developing PHTN by more than seven fold (OD: 7.6, 95 % CI 4.7175 to 12.4, P=0.000) and disorder of nervous system by 12 folds (OD: 12.7 95 % CI: 7.6658 to 21.09, P=0.000). Conclusion: we had found that the prevalence if SCA among Saudi Arabia is 8.8 % with a higher prevalence in female than male. Moreover, the prevalence of PHTN in SCA patients was high about 31.8 % which is much higher than its prevalence in normal individuals. Moreover, it was found that having cardiac disease is considered a risk factor for developing PHTN besides, having diabetic condition and disorder of nervous system which increased risk for developing PHTN in SCA by nine, seven and 12-fold respectively.
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Alslamah, Thamer. "Prevalence of Various non-Communicable Diseases (NCDs) and NCD Risks Factors among Saudi Population-Analysis from SHIS 2013." Pakistan Journal of Medical and Health Sciences 16, no. 1 (January 30, 2022): 710–15. http://dx.doi.org/10.53350/pjmhs22161710.

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Non-communicable diseases like cardiovascular disease, cancer, chronic respiratory diseases and diabetes, along with respective risk factors, pose a public health problem in Saudi Arabia. This study was done using GBD-SHIS data to study the prevalence and risk factors of non-communicable diseases in Saudi Arabia. Data from nationally representative sample collected during Saudi health Interview Survey (SHIS) 2013 was ana-lyzed. Among a total of 10195 respondents, the mean age was 37.9 years (SD 16.1), of which 5252 (51.5%) were female and 6623 (65.0%) were currently married. The most common NCD was asthma (3.65%), followed by myocardial infarction (0.67%) and stroke (0.48%) and renal failure (0.54%). The most common NCD risk factor was ever smoking (17.01%). Diabetes (11.40%) and hypertension (9.38%) were the other common risk factors. All the NCDs were higher in the age group >60 years. The study clearly highlights the high burden of NCDs and their risk factors among Saudi population. The study inputs are extremely useful for government, service providers and population to develop appropriate prevention, screening and management services. Keywords: Non-communicable diseases, Aged, risk factors
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Alshahrani, S., H. Korairi, A. Y. Sharifi, M. A. M. Alqahtani, S. A. AL Qahtani, K. M. A. Ahamed, A. Kaabi, O. M. Alzahrani, and A. Y. Abouelyazid. "Depression: a predictor of coronary heart disease in Saudi Arabia." CARDIOMETRY, no. 22 (May 25, 2022): 147–53. http://dx.doi.org/10.18137/cardiometry.2022.22.147153.

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Aims and Objectives: This research study mainly deals to evaluate the effect of depression in coronary heart disease patients. Background: Depression is one of the common comorbidity among patients presented with acute coronary syndrome or those with major cardiovascular event. Depression has been independently associated or lead to acute cardiac events in patients. Method: The study was conducted from three months followed-up patients with recent diagnosed coronary heart disease and they getting treatment from cardiac centres “Armed Forces Hospitals. Depression was evaluated by using 17-item Hamilton Rating Scale and the cardiac outcome was assessed clinically by echo parameters and cardiac biomarkers such as C-reactive Protein. The data were analysis by SPSS version 23. Results: In this study 83 patients were part of this research. The patients had been picked up from range 18-65 year in which mostly patients were male (75%) than female (25%). Among 83 coronary heart disease patients 29.5% were suffering from depression while 19.5% were on severity. The deterioration factor was significantly influence by depression and smoking. Conclusion: Depression has a great impact on deterioration of the cardiac outcomes. It can serve as a predictive variable for future cardiological morbidity and mortality.
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Kalaf, Hassan, Abdulrahman Almesned, Tark Soomro, Wael Lasheen, Mohamed Ewid, and Abdulrahman A. Al-Mohaimeed. "Cardiovascular Disease Risk Profile among Young Saudi Women of Al-Qassim , Saudi Arabia : A Cross-Sectional Study." International Journal of Health Sciences 10, no. 1 (March 2016): 29–37. http://dx.doi.org/10.12816/0031214.

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Hersi, Ahmad S. "Implantable Cardioverter Defibrillator Therapy: A Single Center Experience in Saudi Arabia." Open Cardiovascular Medicine Journal 4, no. 1 (September 28, 2010): 192–97. http://dx.doi.org/10.2174/1874192401004010192.

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Introduction: Internal Cardioverter Defibrillators (ICD) has been shown to decrease mortality in patients such as those with structural heart disease or at high risk of sudden cardiac death. To date there is no data regarding the clinical features, and outcomes of ICD patients in Saudi Arabia. Accordingly, we explored the clinical features and outcomes of ICD therapy among Saudis. Methods: Patients who had ICD implantation in King Khalid University Hospital from November 2007 until January 2010 were enrolled. Results: One hundred and eight ICD were implanted between November 2007 and February 2010. The mean age was 58.6±13.2 years. The majority were male 94 (87%), the rate of Diabetes Mellitus (DM) was 58.3%, Hypertension (HTN) was 61.1%, and 63% were smokers. The mean ejection fraction (EF) was 24.5%. Of the 108 patient 90(83.3%) had ICD insertion for primary prevention and 18(16.7%) for secondary prevention. Of the 90 patients who ICD for primary prevention 62 (57.4%) had ischemic cardiomyopathy, 39(36.1%) had dilated cardiomyopathy and 7 (6.5%) had channelopathy. Over a mean follow-up of 18 months 4 (3.7%) died. Conclusions: Our study describes for the first time patients characteristic and outcomes for ICD therapy in Saudi Arabia. Our patients are younger and have higher prevalence of risk factors that those in Western countries.
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Al-Nozha, Mansour M., Yaqoub Y. Al-Mazrou, Mohammed R. Arafah, Mohammed A. Al-Maatouq, Mohamed Z. Khalil, Nazeer B. Khan, Akram Al-Khadra, et al. "Smoking in Saudi Arabia and its relation to coronary artery disease." Journal of the Saudi Heart Association 21, no. 3 (July 2009): 169–76. http://dx.doi.org/10.1016/j.jsha.2009.06.007.

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Alkhunaizi, Ahmed M., Adil A. Al-Khatti, and Mansour A. Alkhunaizi. "Prevalence of Microalbuminuria in Adult Patients with Sickle Cell Disease in Eastern Saudi Arabia." International Journal of Nephrology 2018 (2018): 1–6. http://dx.doi.org/10.1155/2018/5015764.

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Background. Proteinuria is a common feature of sickle cell nephropathy (SCN) that can progress to renal insufficiency and end stage renal disease. Microalbuminuria (MA) is the earliest manifestation of SCN and precedes the development of overt proteinuria. In addition to the renal consequences, MA is linked to cardiovascular complications. Periodic screening and early detection of MA allow early intervention that may reduce the risk of progression to advanced renal failure and cardiovascular diseases. Objective. The aim of this study was to investigate the prevalence of MA in patients with SCD in the eastern region of Saudi Arabia. Methods. A prospective cross-sectional observational study was conducted at Johns Hopkins Aramco Healthcare (JHAH). Urine samples of SCD patients 18 years old and older were tested for the presence of MA using urinary albumin over creatinine ratio (ACR). Correlation was tested with multiple variables including age, gender, body mass index (BMI), hemoglobin level, blood pressure, blood transfusion history, pain episodes, and use of hydroxyurea. Results. Urine samples were tested on 72 patients. The mean age of the study cohort was 35±16.9 years. Microalbuminuria was detected in 18 patients (25%). No correlation was found with any of the tested variables. Conclusion. Microalbuminuria is a common finding in patients with SCD in eastern Saudi Arabia. Patients with SCD should be screened for MA, and those with positive tests should probably be treated with antiproteinuric agents that may slow the progression to advanced stages of renal failure and decrease the risk of cardiovascular diseases.
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K. Alkulaib, Faisal, and Abdulrahman A. Harbi. "CASE REPORT: POSSIBLE COVID-19 REINFECTION IN RIYADH, SAUDI ARABIA." International Journal of Advanced Research 10, no. 12 (December 31, 2022): 581–83. http://dx.doi.org/10.21474/ijar01/15876.

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Coronavirus disease 2019 (COVID-19) is a clinical syndrome that results from an infection with a recently discovered strain of coronavirus. Majority of the patients suffering from COVID-19 experience clinically mild to moderate symptoms and do not require specialized clinical care. There are individuals that are asymptomatic and do not present with the clinical signs and symptoms that are characteristic of COVID-19. However, the elderly and individuals with comorbid pathological conditions such as cardiovascular diseases are at a high risk of developing a severe form of COVID-19. Currently, there is no treatment or prevention approach that has been licensed for use by the drug regulatory authorities in the care and management of persons suffering from COVID-19. Nonetheless, there are numerous ongoing clinical trials attempting to find a vaccine or cure for the disease. Since December 2019, COVID-19 has caused significant mortality and morbidity all around the world and the disease has largely disrupted the functioning of global communities. As the number of individuals who have recovered from COVID-19 continues to increase, many countries have started to re-open schools, mosques, and other public places. Medical researchers have therefore focused attention on the likelihood of re-infection with COVID-19 and the importance of acquired immunity in fighting the virus. The case report describes a 29-year-old male patient who after one month of recovery tested positive for COVID-19 infection for a second time. Extended viral shedding, dynamic polymerase chain reaction (PCR) results, and reinfection are some of the common reasons for a post-recovery positive test for COVID-19.
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Almilaibary, Abdullah. "A Systematic Review of Epidemiolocal, and Time-Trend Prevalence of Obesity-Related Comorbidities and their Health Effects in Saudi Arabia." Bioscience Biotechnology Research Communications 15, no. 1 (March 25, 2022): 01–04. http://dx.doi.org/10.21786/bbrc/15.1.2.

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There has been significant westernization in Saudi Arabia and is one of the countries with the highest prevalence rates of overweight and obesity. According to the study, obesity has become a substantial cause of concern in the country, whereby 70% of people experienced the problem. Obesity was associated with obstructive sleep apnea and osteoarthritis. A systematic and comprehensive search of the selected keywords on PubMed, Medline, and Saudi Digital Library (SDL) database was conducted between November 2020 and January 2021. The result of our study suggests that the prevalence of adult and childhood obesity in Saudi Arabia is extremely high and currently it is undergoing a fast-growing rate of obesity crisis. Genetic factors, reduced physical activity, and high caloric intake contribute to its prevalence. Because of its association with other cardiovascular diseases, it is regarded as a significant matter of concern in Saudi Arabia. Obesity currently considered an epidemic and therefore, is a major public health concern.
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Bazaid, Abdulrahman S., Ahmed A. Punjabi, Abdu Aldarhami, Husam Qanash, Ghaida Alsaif, Hattan Gattan, Heba Barnawi, Bandar Alharbi, Abdulaziz Alrashidi, and Abdulaziz Alqadi. "Bacterial Infections among Patients with Chronic Diseases at a Tertiary Care Hospital in Saudi Arabia." Microorganisms 10, no. 10 (September 26, 2022): 1907. http://dx.doi.org/10.3390/microorganisms10101907.

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Infections caused by multi-drug-resistant bacteria in patients with chronic diseases have been associated with high mortality and morbidity. While few reports have evaluated bacterial infections in multiple chronic disease patients, the focus of the current study was to investigate the prevalence of bacterial infections and the susceptibility profiles of causative strains among various groups of patients suffering from chronic diseases. Microbiological reports of patients suffering from cancer, diabetes mellitus, cardiovascular diseases, kidney diseases, and skin burns were retrospectively collected from a tertiary hospital in Saudi Arabia. Approximately 54.2% of recruited patients were males, and positive urine was the most prevalent specimen associated with kidney disease patients (25%). Escherichia coli isolates were predominant among cardiovascular, kidney, and cancer patients. Staphylococcus aureus was commonly detected in diabetics and those with burns. Although resistance patterns varied based on the type of specimens and underlying diseases, Escherichia coli showed limited resistance to colistin, carbapenems, and tigecycline, while S. aureus demonstrated susceptibility to ciprofloxacin, gentamicin, and rifampin. These observations are crucial for clinicians and policymakers to ensure effective treatment plans and improve outcomes in these patients with comorbidity.
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Kinsara, A. J., T. Alsafrani, O. Khojah, A. W. Abukhodair, R. Alamri, and E. Jastania. "Cardiovascular disease risk factors in the community of the western region of Saudi Arabia." Atherosclerosis 331 (August 2021): e270-e271. http://dx.doi.org/10.1016/j.atherosclerosis.2021.06.830.

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Al-Dahi, Salem, Hesham Al-Khashan, Mohamed Abdullah Mashhour Al Madeer, Khaled Al-Saif, Mohamed Dhafer Salih Al-Amri, Othman Al-Ghamdi, Nabil Al-Helali, Mohie Selim, and Adel Mounir Mishriky. "Assessment of Framingham Cardiovascular Disease Risk Among Militaries in the Kingdom of Saudi Arabia." Military Medicine 178, no. 3 (March 2013): 299–305. http://dx.doi.org/10.7205/milmed-d-12-00079.

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Alquaiz, AlJohara M., Ambreen Kazi, Riaz Qureshi, Amna Rehana Siddiqui, Amr Jamal, and Shaffi Ahamed Shaik. "Correlates of Cardiovascular Disease Risk Scores in Women in Riyadh, Kingdom of Saudi Arabia." Women & Health 55, no. 1 (January 2, 2015): 103–17. http://dx.doi.org/10.1080/03630242.2014.972020.

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Faisal, Ahmed, Mahmoud Elshahat, Reda Goweda, Arij Alzaidi, Bashaer Aldhawani, and Hibah Alharbi. "Cardiovascular Disease Risk Factors among Non-Alcoholic Fatty Liver Disease Patients at Makkah, Kingdom of Saudi Arabia." Global Journal of Health Science 8, no. 11 (March 1, 2016): 45. http://dx.doi.org/10.5539/gjhs.v8n11p45.

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<p><strong>BACKGROUND:</strong> Non-alcoholic fatty liver disease (NAFLD) is one of the major health problems which is characterized by excessive fat accumulation in the liver. Worldwide, NAFLD has a reported prevalence of 6 to 35 percent in the general population. The prevalence of NAFLD has increased as more patients develop a sedentary lifestyle, metabolic syndrome, and obesity.</p><p><strong>AIM &amp; OBJECTIVES:</strong> To study cardiovascular disease risk factors among NAFLD patients aiming to reduce morbidity and mortality.</p><p><strong>METHODOLOGY:</strong> This was a cross sectional study. Cardiovascular risk factors questionnaire including personal data, BMI, lipid profile and blood pressure was used to obtain the data from 150 patients with ultrasound diagnosed NAFLD and 150 patients with no evidence of NAFLD at Umm Al Qura University medical center, Makkah, Kingdom of Saudi Arabia.</p><p><strong>RESULTS:</strong> 54.7% out of 150 NAFLD patients were males, 91.3% were obese, 50.7% were diabetics, 28% hypertensive, 53.7% had high cholesterol level, 52.7 % had high triglycerides and 64.6% had high LDL level. Results showed significant high prevalence of most of CVD risk factors among NAFD patients in comparison to age matched group of patients without NAFLD.</p><p><strong>CONCLUSION:</strong> NAFLD patients have a high risk of cardiovascular diseases more than non NAFLD.<strong></strong></p>
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Al-Rahimi, Jehan S., Nada M. Nass, Shahira A. Hassoubah, Dhuha Y. Wazqar, and Soha A. Alamoudi. "Levels and predictors of fear and health anxiety during the current outbreak of COVID-19 in immunocompromised and chronic disease patients in Saudi Arabia: A cross-sectional correlational study." PLOS ONE 16, no. 4 (April 26, 2021): e0250554. http://dx.doi.org/10.1371/journal.pone.0250554.

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Coronavirus disease 2019 (COVID-19) infection has become a clinical threat to healthy people as well as immunocompromised patients and those with pre-existing chronic diseases around the world. This study, which used a cross-sectional correlational design, aimed to assess the levels of fear and health anxiety and to investigate their predictors during the current outbreak of COVID-19 in immunocompromised and chronic disease patients in Saudi Arabia. Sociodemographic and clinical data, fear of COVID-19, and health anxiety measurements were collected by online surveys from June 15 to July 15, 2020. Univariate and multiple linear regression analysis was used to identify predictors. A total of 1,030 patients in 13 provinces in Saudi Arabia completed the questionnaire. A significant number of patients with chronic diseases experienced considerable levels of fear and anxiety during the COVID-19 outbreak. It was found that 21.44% of participants met the criteria for anxiety cases, and 19.4% were considered borderline anxiety cases. In regression analysis, significant predictors of fear and health anxiety were female gender, lower education, middle-aged, divorced or widowed, receiving immunosuppressants, type of chronic disease (Crohn’s disease, hypertension, and cardiovascular diseases), and media use as a source of knowledge about COVID-19. Immunocompromised and chronic disease patients are vulnerable to fear and anxiety during epidemic infectious diseases such as COVID-19. Optimizing this population’s compliance with appropriate infection prevention and control strategies is crucial during the infectious outbreaks to ensure their safety, to decrease the risk of infection and serious complications, and reduce their fear and health anxiety. Effective positive psychological interventions and support strategies also need to be immediately implemented to increase psychological resilience and improve the mental health of these patients. Due to the COVID-19 outbreak, chronic disease patients in Saudi Arabia need special attention from health authorities, policymakers, and healthcare professionals to manage maladaptive forms of health anxiety and fear.
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Saleem, Naof Faiz, Mahmoud Fathy ElSharkawy, and Ayman M. Azoz. "Effect of Airborne Particulate Matter on Cardiovascular Diseases." Atmosphere 13, no. 12 (December 2, 2022): 2030. http://dx.doi.org/10.3390/atmos13122030.

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Context: Airborne particulate matter (PM) attracts heightened attention due to its implication in various diseases, especially cardiovascular diseases. Although numerous epidemiological studies have been published worldwide in developing countries on risks associated with exposure to PM, such studies are still scarce in developing countries such as Saudi Arabia. Objective: To examine the association between the concentration of airborne particulate matter (PM) and hospital admissions resulting from cardiovascular diseases (CVD) in the Eastern Region of Saudi Arabia, specifically in the cities of Dammam and Khobar. Methodology: The daily concentrations of PM10 and PM2.5 were obtained from 10 monitoring stations distributed around the two hospitals. There was an examination of the discharge data of patients diagnosed with cardiac arrhythmias, acute myocardial infarction, and heart failure as their primary diagnoses. The data were obtained from two big governmental hospitals in the Eastern Region. The primary cause of hospital admission of 259 patients was identified as acute cardiac condition. Results: For PM10 and PM2.5, the 24 h mean was calculated as 101.2 and 37.1 µg/m3, respectively; such means are considered higher than the Air Quality Guidelines (AQGs). We found evidence of an increased risk of cardiovascular events for long-term exposure to PM2.5–10 concentrations, and a correlation with the IHD hospital admission within 6 days of the peak PM10 or PM2.5 concentration. In addition, the increased PM2.5 concentration also had a correlation with hospital admissions; however, analysis shows an increase in mortality at lag1, lag2, and lag3 prior to hospital admission. Conclusions: Hospital admissions for several cardiovascular diseases acutely increase in response to higher ambient PM concentrations. It is recommended that residents need to use personal protection, especially those residents with cardiovascular disease, while the government needs to strengthen the governance of air pollution in areas with lighter air pollution.
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Alkhaldy, Areej, Reem Alamri, Rozana Magadmi, Nrvana Elshini, Rania Hussein, and Kamal Alghalayini. "Dietary Adherence of Saudi Males to the Saudi Dietary Guidelines and Its Relation to Cardiovascular Diseases: A Preliminary Cross-Sectional Study." Journal of Cardiovascular Development and Disease 6, no. 2 (April 4, 2019): 17. http://dx.doi.org/10.3390/jcdd6020017.

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Cardiovascular disease (CVD) is a major public health problem in Saudi Arabia. Dietary intake plays a major role in CVD incidence; however, the dietary intake status in Saudi nationals with CVD is unknown. We aimed to investigate whether the dietary patterns of Saudi males, using the Saudi dietary guidelines adherence score, in parallel with the measurement of a selective number of cardiovascular disease-related biomarkers, are contributing factors to CVD risk. Demographics, dietary adherence score, and blood biomarker levels were collected for 40 CVD patients and forty non-CVD patients. Fasting blood glucose (p = 0.006) and high-density lipoprotein levels (p = 0.03) were significantly higher in CVD patients. The adherence score to the Saudi dietary guidelines was not significantly different between the CVD and non-CVD patients; however, the specific adherence scores of fruit (p = 0.02), olive oil (p = 0.01), and non-alcoholic beer (p = 0.02) were significantly higher in the non-CVD patients. The differences in CVD family history (p = 0.02) and adherence scores to specific groups/foods between the CVD and non-CVD patients may contribute to CVD risk in Saudi males. However, as the sample size of this study was small, further research is required to validate these findings.
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Ahmed, Shereen Helmy, Yumna Abdulmalek Bokhari, Rana Jamal Nahas, Amjad Zaki Alharbi, Asrar Abdullah Niyazi, and Renad Abdulwahab AlGaedy. "Public Knowledge of Cardiovascular Diseases and its Risk Factors in Jeddah City, Saudi Arabia." International Journal of Innovative Research in Medical Science 6, no. 09 (September 2, 2021): 506–11. http://dx.doi.org/10.23958/ijirms/vol06-i09/1182.

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Introduction: Cardiovascular diseases (CVDs) are one of the critical yet preventable non-communicable diseases. Based on the World Health Organization (WHO) reports on non-communicable conditions in 2010, millions of people were killed by non-communicable diseases in 2008, resulting in deaths that occurred before the age of 60 (1). Our aim in this study is to provide descriptive epidemiology and to estimate the public’s knowledge towards CVD types, risk factors, and warning symptoms of heart attack or stroke. Methodology: The study was approved by Ibn Sina National College of Medical Sciences research committee in November of 2019.This is a cross-sectional analytic study conducted among the Saudi community in Jeddah City, Saudi Arabia from November 2019 to April 2020. A total of 635 respondents contributed to fill the self-administered questionnaire. Statistical package for social sciences (SPSS) version 20 was used. The degree of association was tested using Chi-square. A statistically significant association was taken at P<0.05. Results: Participants who agreed to participate consisted of 228(35.9%) males and 407(64.1%) females. Hypertension is the highest disease diagnosed with a total of 111(17.5%) and highest among females with 71(64.0%). Most of the participants identified chest pain and discomfort (76.4%) and shortness of breath (73.7%) as symptoms of heart attack. Compared with other symptoms such as pain or discomfort in the arm or shoulder (57.3%), weakness in the arm or leg on one side of the body (55.6%), and weakness lightheaded and fainting (51.2%). Conclusion: The study participants show low knowledge in CVS. There is a need to increase public awareness and to establish basic knowledge to the general and targeted individuals.
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Amin, Md Nurul, Md Rafiqul Islam, and Md Rafiqul Islam. "Pattern of diseases among Bangladeshi Hajj Pilgrimsin Mecca, Saudi Arabia." Ibrahim Cardiac Medical Journal 10, no. 1-2 (March 15, 2021): 96–101. http://dx.doi.org/10.3329/icmj.v10i1-2.54010.

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Background & objective: Each year millions of Muslims embark on a religious pilgrimage called the “Hajj” to Mecca in Saudi Arabia. The mass migration during the Hajj is unparalleled in scale, and pilgrims face numerous health hazards. Performing the tasks of pilgrimage is stressful and laborious and as such requires immense mental and physical fitness on the part of the pilgrims. But a substantial proportion of the pilgrims lack it. Besides, the hot and dry environment and untold overcrowding predispose them to the risk of many communicable diseases. The present study, was therefore, intended to find the pattern of diseases among Bangladeshi Hajj pilgrims at Mecca, Saudi Arabia. Methods: This descriptive cross-sectional study was carried out on Bangladeshi Hazz pilgrims in Mecca Saudi Arabia over a period of 1 month from mid-September to mid-October, 2015. A total of 710 pilgrims (18 or > 18 years) attending at Bangladeshi Hazz Medical Center (BHMC) in Mecca, Saudi Arabia during the period were consecutively included in the study after having voluntary verbal consent obtained from them. Diseases were diagnosed mainly on the basis of clinical signs and symptoms with provision of only random and fasting blood sugar estimation and ECG. The diagnosed diseases were grouped into major and minor problems or conditions and were treated as out-patient basis. Result: In the present study upper middle-aged (50 – 60 years) and elderly (≥ 60 years) pilgrims together formed nearly 73% of the patients with mean age of the patients being 56 years. Males were a bit higher than the females with male-female ratio being roughly 11:9. The study demonstrated that the commonest cause of out-patient visit was respiratory illness (41.2%) followed by diabetes (17.2%), peptic ulcer disease (PUD) (11.7%) and cardiovascular diseases (10.7%)(which included hypertension, new onset ischemia or exacerbation of preexisting ischemic heart diseases). A few (3.2%) of the patients presented with diarrhoeal diseases (loose motion or dysentery). Other minor ailments were allergy or dermatitis, insomnia, paronychia, anxiety, UTI, hemorrhoids, epistaxis, glossitis, oral ulcer, earache, conjunctivitis, worm infestation, spot bleeding etc., accounting for 4.8% of the patients. Conclusion: The study concluded that respiratory illness is the most common health problems among pilgrims visiting to Mecca, Saudi Arabia followed by diabetes, PUD and cardio-vascular diseases. The pilgrims should be educated in their home country before starting for pilgrimage as how to maintain their health in their new and challenging environment and Bangladesh Hazz Mission in Mecca should ensure enough medical support to them. Ibrahim Card Med J 2020; 10 (1&2): 96-101
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Gutierrez, Jeneth, Aladeen Alloubani, Mohammad Mari, and Mohammad Alzaatreh. "Cardiovascular Disease Risk Factors: Hypertension, Diabetes Mellitus and Obesity among Tabuk Citizens in Saudi Arabia." Open Cardiovascular Medicine Journal 12, no. 1 (April 23, 2018): 41–49. http://dx.doi.org/10.2174/1874192401812010041.

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Background:Cardiovascular Disease (CVD) is considered as the main cause of death worldwide. Identifying the links among CVDs risk factors can help decrease CVD-related deaths.Aim:To assess the prevalence of risk factors for CVD and their relationships among the Tabuk City population in Saudi Arabia.Methods:A cross-sectional design was used; 432 participants in the Tabuk region were included in this study.Results:The prevalence of diabetes mellitus (DM) was 5.6%, the prevalence of hypertension (HTN) was 11.1% and obesity and overweight together were 69.9%. Mean Body Mass Index (BMI), HTN, and DM increased with age. There was a correlation between BMI with HTN (r=.200, p<.001), BMI and DM (r=.149, p<.001) and DM and HTN (r=.366, p<.001).Conclusion:Public awareness may help in reducing the prevalence of CVD.
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Koura, HalaM, ShehabA Alenazi, SherifM Zaki, and AymanH Mohamed. "Prevalence of obesity among male adolescents in Arar Saudi Arabia: Future risk of cardiovascular disease." Indian Journal of Community Medicine 40, no. 3 (2015): 182. http://dx.doi.org/10.4103/0970-0218.158864.

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Alzahrani, Hasan A., Dong Wang, Balkees A. Bakhotmah, and Frank B. Hu. "Risk factors for peripheral artery disease among patients with diabetes in Saudi Arabia." Vascular Medicine 19, no. 2 (March 12, 2014): 103–11. http://dx.doi.org/10.1177/1358863x14526948.

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Mohamed, Nagwa A. "Prevalence of Risk Factors for Diabetes Mellitus and Hypertension Among Adult in Tabuk - Kingdom of Saudi Arabia." Open Access Macedonian Journal of Medical Sciences 7, no. 5 (March 16, 2019): 831–37. http://dx.doi.org/10.3889/oamjms.2019.046.

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BACKGROUND: Cardiovascular disease (CVD) is a common but chronic condition that can cause death, and is seen as a substantial source of disability and health costs. A balance between prevention and intervention, as is the case with other infectious diseases, is the best way to stem the increasing burden of CVD. AIM: This study assesses the prevalence of diabetes mellitus, hypertension, in a sample from the University of Tabuk. METHODS: A cross-sectional study was done in 2018, with 120 employees and students at the University of Tabuk (in Tabuk City, Saudi Arabia), for those over age 20 (60 males and 60 females) from different faculties and departments at the university. RESULTS: Assessment was done with 120 participants to assess the prevalence of hypertension and diabetes mellitus, at the University of Tabuk, in which the prevalence is actually higher than in most cities of Saudi Arabia. Ten percent of participants are hyperglycemic and 10% are developing problems in that area, with no significant difference between males and females. CONCLUSION: This study shows that cardiovascular risk factors will influence those with major health disorders in the future. Consequently, a nationwide campaign encouraging wholesome eating, better lifestyles, as well as physical activity, is a healthcare priority.
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Alallaf, Faisal, Fatima Amanullah H.Nazar, Majed Alnefaie, Adel Almaymuni, Omran Mohammed Rashidi, Khalid Alhabib, Fahad Alnouri, Mohamed-Nabil Alama, Mohammad Athar, and Zuhier Awan. "The Spectrum of Familial Hypercholesterolemia (FH) in Saudi Arabia: Prime Time for Patient FH Registry." Open Cardiovascular Medicine Journal 11, no. 1 (July 26, 2017): 66–75. http://dx.doi.org/10.2174/1874192401711010066.

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Background:Familial hypercholesterolemia (FH) is a life-threatening inherited condition. Untreated patients have the risk to develop raised plasma levels of cholesterol, atherosclerosis and cardiovascular disease (CVD). If diagnosed and treated early in life, the pathological consequences due to atherosclerosis could be avoided and patients with FH can have an anticipated normal life. Mounting evidence suggests that FH is underdiagnosed and undertreated in all populations. The underlying molecular basis of FH is the presence of mutations in one or more genes in the low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB) or proprotein convertase subtilisin/kexin 9 (PCSK9). However, their prevalence is largely unknown in Saudi Arabia but given the high rates of consanguinity, the prevalence appears to be higher. Furthermore, the high prevalence of obesity and diabetes mellitus in Saudi Arabia increases the vascular disease burden in FH cases by adding additional CVD risk factors.Objective:This article explores the spectrum of FH-causing mutations in the highly consanguineous Saudi community, the need for establishing the Saudi FH registry, the challenges in creating gene databases, and cascade screening.Conclusion:The establishment of FH registry and genetic testing should raise awareness not only among healthcare professionals, but the general population as well. It also helps to provide the best treatment regimen in a cost effective manner to this under-recognised population of FH patients.
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Hasan Sulimani, Zainbganayah, Manal Abdulaziz Murad, Amal Mohammed Abushal, Mohsen Daghustani, Joud Nasir Bazaid, Malak Mohammed Al-Jraib, Shahad Abid Alsreihi, et al. "A CROSS-SECTIONAL STUDY OF THE IMPACT OF ENDODONTIC INFECTIONS ON THE PATHOGENESIS OF CARDIOVASCULAR DISEASE." International Journal of Advanced Research 8, no. 12 (December 31, 2020): 888–94. http://dx.doi.org/10.21474/ijar01/12229.

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Introduction: The apical periodontitis possesses an association with the increased inflammatory markers levels, which contribute to the systematic immune response, leading towards systematic inflammation. The endodontic infections were reported to contribute to the CVD via the metastatic pathways however, there is a requirement to analyse the impact of endodontic infections on the pathogenesis of the cardiovascular disease. Aim:This research aims to assess the impact of endodontic infections on the pathogenesis of the cardiovascular disease. Material andMethod:This research was conducted using a cross-sectional research design by recruiting N=120 inpatients and outpatients visiting the healthcare organisation located in Saudi Arabia. Results:The endodontic infections are likely to increase the overall inflammatory burden, which might increase the risk of CVD among the individuals. Due to the multifactorial aetiology of CVD, the oral diseases are perceived to possess associated with the CVD. Thestatistical analysis revealed that there is no association between the presence of the lesion of endodontic origin and cardiovascular diseases. Conclusion:There is no association between the presence of the lesion of endodontic origin and cardiovascular diseases.
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Naim, Juniarty, Wahiduddin Wahiduddin, Masni Masni, Ridwan Amiruddin, Irwandy Irwandy, and M. Nadjib Bustan. "Determinants of Coronary Heart Disease Incidence among Indonesian Hajj Pilgrims Hospitalized in Saudi Arabia in 2019." Open Access Macedonian Journal of Medical Sciences 9, E (September 7, 2021): 798–804. http://dx.doi.org/10.3889/oamjms.2021.6776.

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BACKGROUND: Cardiovascular diseases (CVDs) are the main causes of death worldwide, including in the hajj pilgrims. Coronary heart disease (CHD) is the most common CVDs in Indonesian hajj pilgrims hospitalized in Saudi Arabia. AIM: This study aimed to determine the determinants of the CHD incidence among Indonesian hajj pilgrims hospitalized in Saudi Arabia in 2019. METHODS: This study was an observational analytic study with a case–control design. The study was conducted in Makassar using data from the integrated Hajj computerized system in the health sector (siskohatkes) Hajj Health Center (Puskeshaji) in January–June 2021. Cases were pilgrims hospitalized in Saudi Arabia with a diagnosis of CHD, about 186 people, and controls were pilgrims hospitalized with diagnoses other than CVDs. Selection of controls by matching age and sex with a ratio of 1:1. The determinants analyzed included education, high blood pressure, high blood sugar levels, high low-density lipoprotein (LDL) cholesterol levels, excess body mass index (BMI), and smoking. Data analysis was using the STATA program with an odds ratio (OR) test and multiple logistic regression. RESULTS: The most respondents were 65 years (48.39%), female respondents, about 61.83%. Most respondents’ education was in elementary school, about 31.99%. Multivariate analysis showed that high blood pressure (OR = 2.32, 95% confidence index [CI] = 1.50–3.57), high blood sugar levels (RO = 1.90, 95% CI = 1.06–3.40), high LDL cholesterol levels (RO = 1.82, 95% CI = 1.15–2.88), and excess BMI (RO = 1.73, 95% CI = 1.07–2.68) were risk factors for the CHD incidence. However, education and smoking were not risk factors for CHD. CONCLUSION: By multiple logistic regression analyzes, the study revealed that the probability of CHD when having those four risk factors was 85.69%.
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Alkattan, Abdullah N., Ahmed S. Alkhalifah, and Eman A. Alsalameen. "The Effect of Glycated Hemoglobin on the Prognosis of Diabetic Patients: A Cross-Sectional Observational Study." Saudi Journal of Internal Medicine 9, no. 1 (June 30, 2019): 5–11. http://dx.doi.org/10.32790/sjim.2019.9.1.2.

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Objectives: Diabetes mellitus is a chronic metabolic disorder characterized by elevation of blood glucose and a high percentage of glycated hemoglobin A1c. Elevated hemoglobin A1c percentage of more than 7% will result in high production of advanced glycation end-products. Th e elevated level of advanced glycation end-products in diabetic patients means a high risk for diabetic complications. Th e primary endpoint was to evaluate the hemoglobin A1c levels among diabetic patients and its effect on the prognosis of this metabolic disease in all regions inside Saudi Arabia. Methods: Th is was a cross-sectional observational study conducted between March and August 2018. Th e study was done by using a questionnaire containing nine questions which planned to involve at least 390 diabetic patients. Results: Six hundred and ninety-four diabetic patients from Saudi Arabia had answered the nine-question questionnaire about hemoglobin A1c percentage and prognosis of diabetes. Th e mean age of these patients is 43.4 years old and most of those patients (75.5%) were visiting governmental hospitals. Th e number of diabetic patients having hemoglobin A1c less than 7% are 259 patients with hemoglobin A1c mean 6.66% + 3.33%, however, there are 435 patients having hemoglobin A1c more than 7% with mean equals 7.75% + 1.2%, the difference between them is statistically significant (P value < 0.0001). Conclusion: Th e glycated hemoglobin of diabetic patients in all regions of Saudi Arabia was significantly elevated and uncontrolled based on most diabetic guidelines and significantly affects the prognosis by causing diabetic complications especially cardiovascular diseases.
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Almashaykhi, Ahmed Obaid, Randa M Nooh, Sami Said Almudarra, Abdulaziz Saad ALMutari, Naif Saud ALBudayri, Khalid Masoud AlGhamdi, and Ali Aldarwish. "The Pattern of Referral of Sick Omani Pilgrims From the Omani Medical Mission During Hajj 2019." Iproceedings 8, no. 1 (February 8, 2022): e36393. http://dx.doi.org/10.2196/36393.

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Background Annually, in the month of Dhul hijjah, over 2 million Muslims travel to Saudi Arabia to perform hajj. Hajj is the biggest mass gathering globally, which creates a substantial influence on hajjes’ health. The Omani medical mission is the official delegation from the Omani government to Saudi Arabia to serve the Omani hajjees regarding their health issues. Objective This study investigates the referral rate and pattern of diseases among hajjees referred by the Omani medical mission during Hajj 1440 H. Methods We conducted a cross-sectional study at the Omani Medical missions in Makkah, Madinah, Mina, and Arafat. Data was collected via a predesigned form. All Omani pilgrims presenting to the mission who were referred to local hospitals were included. Results The total number of cases was 5000, of which 106 (2.1%) were referred to local hospitals (21.2 per 1000 hajjees). The most common causes of referral were cardiovascular diseases (23.6%), followed by gastrointestinal disease (17.9%) and trauma (16.9%). Male patients comprised 60.1% of the sample. Their mean age was 47.3 (SD 11.27) years, with the highest referrals in the 51-60 years age group (30%). Over half (55.7%) had comorbidities. Patients’ mean time to reach the clinic was 8.87 (SD 6.41) minutes, with 65% arriving in 5 minutes or less. The mean time needed to reach the hospital by ambulance was 11.39 (SD 6.6) minutes, with 36% arriving within 5 minutes. Of the referrals, 42% were admitted into the hospital. Hospitalization was significantly higher among patients with chest pain (P<.006), diabetics (P<.001), and patients with heart disease (P=.01). Conclusions The most common causes for referral of hajjees from the Omani Medical Mission were cardiovascular diseases, gastrointestinal disease, and trauma. This information should assist the Omani government in planning their medical services in the hajj season in future years.
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Kinsara, Abdulhalim J., Hani K. Najm, Menwar Al Anazi, and Hani Tamim. "Resting heart rate in patients with ischemic heart disease in Saudi Arabia and Egypt." Journal of the Saudi Heart Association 23, no. 4 (October 2011): 225–32. http://dx.doi.org/10.1016/j.jsha.2011.05.001.

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48

Wali, Siraj O., Muath A. Alsharif, Mohammed H. Albanji, Murad S. Baabbad, Haneen M. Almotary, Nabil Alama, Layth Mimish, Adil Alsulami, and Muntasir M. Abdelaziz. "Prevalence of obstructive sleep apnea among patients with coronary artery disease in Saudi Arabia." Journal of the Saudi Heart Association 27, no. 4 (October 2015): 227–33. http://dx.doi.org/10.1016/j.jsha.2015.03.004.

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49

Al-Daghri, Nasser, and Omar Al-Attas. "Homocysteinemia, hypertension, and family history of diabetes in a smoking male population in Saudi Arabia." Open Medicine 3, no. 2 (June 1, 2008): 167–72. http://dx.doi.org/10.2478/s11536-008-0019-9.

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Abstract:
AbstractArabs have a lower incidence of atherosclerosis than other ethnicities, but few studies have examined homocysteine (HCYS) as a risk factor for cardiovascular disease in this population. Here, we investigated the association between serum HYCS levels and risk factors for cardiovascular disease (smoking, hypertension, and family history of diabetes) in Saudi males. A total of 50 smokers and 72 nonsmokers completed a general health questionnaire. In addition, their lipid profiles were measured using routine methods and HCYS levels by high-performance liquid chromatograph with electrochemical detection. Regression analysis showed negative associations between HCYS and glucose (r = −0.22; P < 0.05) as well as family history of diabetes (r = −0.21; P < 0.05). HCYS levels were similar between hypertensive and nonhypertensive smokers, but they were significantly elevated in hypertensive nonsmokers (P = 0.027) and lower in smokers with family history of diabetes (P = 0.01). Levels of HCYS among nonsmokers inversely correlated with history of diabetes and elevated glucose. Nonsmokers’ HCYS levels were significantly elevated in the presence of hypertension and correlated with diastolic blood pressure. Thus, HCYS may be a predictor of hypertension among nonsmokers. Until further trials are conducted, we recommend vitamin B6/folic acid supplementation for the Saudi hypertensive population as an adjuvant therapy.
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50

Briones, Ana, and Marisol Fernández-Alfonso. "Report on the 24th meeting of the ECCR 8th-9th October 2021." Clinical Science 135, S1 (November 22, 2021): 1. http://dx.doi.org/10.1042/cs2021eccr001-mr.

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The 24th meeting of the European Council for Cardiovascular Research (ECCR) was virtual and held online on October 8th and 9th, 2021. Over 130 participants including trainees, early career researchers (ECR) and established investigators from eleven European countries (Austria, Denmark, France, Germany, Italy, Netherlands, Poland, Slovenia, Spain, Turkey, U.K.), and participants also from Canada, Chile, Saudi Arabia, and the U.S.A. connected to enjoy two days of outstanding research. The meeting was opened by its president, Professor Marisol Fernandez-Alfonso from the Complutense University in Madrid and covered several topics of cardiovascular research: from vascular and metabolic aspects to novel immunological mechanisms of cardiovascular disease.
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