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Dissertations / Theses on the topic 'Cardiovascular Diseases – therapy'

Author: Grafiati

Published: 4 June 2021

Last updated: 19 February 2022

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1

Mazlan-Kepli, Wardati. "Antiplatelet therapy and clinical outcomes in cardiovascular diseases." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7831/.

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Cardiovascular diseases (CVD) is a leading cause of death in the world. Despite effective treatment regimens for ischaemic heart disease (IHD) and ischaemic stroke, mortality and recurrence rates remain high. Antiplatelet therapy is on effective treatment and reduces the risk of recurrent heart attack and stroke. Nevertheless, there are patients who stopped or interrupted their antiplatelet therapy for certain reasons or some patients may be resistant or poor responders to antiplatelet therapy. Furthermore, there is evidence of rebound effect in platelet activity after antiplatelet cessation a

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2

DiPeri, Timothy P. "Neuromodulation Therapy Mitigates Heart Failure Induced Hippocampal Damage." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/honors/208.

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Cardiovascular disease (CVD) is the leading cause of death in the United States. Nearly half of the people diagnosed with heart failure (HF) die within 5 years of diagnosis. Brain abnormalities secondary to CVD have been observed in many discrete regions, including the hippocampus. Nearly 25% of patients with CVD also have major depressive disorder (MDD), and hippocampal dysfunction is a characteristic of both diseases. In this study, the hippocampus and an area of the hippocampal formation, the dentate gyrus (DG), were studied in a canine model of HF. Using this canine HF model previously, we

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3

Loke, Wai Mun. "Cardiovascular protective effects of dietary polyphenols." University of Western Australia. School of Biomedical and Chemical Sciences, 2008. http://theses.library.uwa.edu.au/adt-WU2009.0051.

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Polyphenols are naturally-occurring phytochemicals, which form an integral part of the human diet. Results from epidemiological studies have associated polyphenol intake with reduced risk of cardiovascular diseases. Previous human intervention studies suggested that dietary polyphenols exert their cardioprotective effects through their antioxidant and anti-inflammatory effects. While most in vitro experiments have not accounted for the bioavailability and metabolism of these polyphenols, our work has provided direct evidence, using quercetin, that metabolic transformation, together with bioava

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4

Cheung, K. K. "Application of stem cell therapy and magnetic resonance imaging in experimental models of cardiovascular diseases." Thesis, University College London (University of London), 2010. http://discovery.ucl.ac.uk/19292/.

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The incidence of cardiovascular diseases has continued to rise despite better understanding of their pathogenesis, and while mortality is declining with advances in treatment, morbidity has increased dramatically due to the chronic complications of surviving the initial event. In contrast to existing interventions, which primarily aim at limiting tissue damage, stem cell therapy has recently emerged as a novel interventional paradigm where damaged myocardial and other vascular tissues can be regenerated and repaired through transplantation of these primitive cells. This Thesis describes a numb

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5

Pripp, Ulla. "The effect of sex hormones on hemostasis and cardiovascular riskfactors in postmenopausal women /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-982-X/.

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6

Karjalainen, A. (Anna). "Effect of estrogen replacement therapy on metabolic risk factors for cardiovascular diseases in hysterectomized postmenopausal women." Doctoral thesis, University of Oulu, 2003. http://urn.fi/urn:isbn:9514272404.

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Abstract Estrogen replacement therapy (ERT) has been associated with favorable effects on risk factors for atherosclerosis. In observational studies ERT was also suggested to reduce the risk of cardiovascular disease in postmenopausal women, but the cardioprotective role of estrogen has been challenged after negative results in randomized trials. However, the mechanisms of estrogen action in atherosclerosis development are only partially known. In order to investigate the regulation of plasma low-density lipoprotein (LDL) cholesterol in postmenopausal women and the effects of ERT on choleste

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7

Ng, Fook-hong, and 吳福康. "Management of adverse gastrointestinal events in patients with anti-platelet therapy." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41290963.

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8

Ting, Kuei-fu Lily. "Postmenopausal hormone replacement therapy and its effects on lipoprotein metabolism, oxidation and bone related biochemcialvariables." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31241062.

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9

Shi, Jun. "Constructing FHNNs to detect CVDs through hemodynamic parameters derived from sphygmogram." Thesis, University of Macau, 2011. http://umaclib3.umac.mo/record=b2493321.

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10

Shultz, Jennifer M. "Effects of sex steroids and diet on adipose distribution and cardiovascular disease risk factors /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/6592.

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11

Moorhead, Pamela K. (Pamela Kay). "The Comparison of Mandatory and Voluntary Compliance to Diet and Exercise Regimens Among Cardiovascular High Risk Seminary Theological Students." Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc500396/.

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This study evaluated a mandatory fitness assessment and counseling program designed to reduce coronary risk factors related to diet and exercise. The study was conducted at a southwestern graduate level theological institution. There were 19 mandatory and 22 voluntary participants. Each subject initially had either high blood pressure, high percentage body fat, or high total cholesterol. Significant changes were made within both groups regarding body fat percentage and diastolic blood pressure. Total cholesterol levels decreased for the voluntary group only. The mandatory group significantly i

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12

Rodriguez-Macias, Wallberg Kenny A. "Artery Wall Imaging and Effects of Postmenopausal Estrogen Therapy." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5722.

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13

Hariri, Essa H. "Are We Optimizing the Use of Dual Antiplatelet Therapy in Patients Hospitalized with Acute Myocardial Infarction?" eScholarship@UMMS, 2019. https://escholarship.umassmed.edu/gsbs_diss/1010.

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Background: Dual antiplatelet therapy (DAPT) is a mainstay treatment for hospital survivors of an acute myocardial infarction (AMI). However, there are extremely limited data on the prescribing patterns of DAPT among patients hospitalized with AMI. Objective: To examine decade-long trends (2001-2011) in the use of DAPT versus antiplatelet monotherapy and patient characteristics associated with DAPT use. Methods: The study population consisted of 2,389 adults hospitalized with an initial AMI at all 11 central Massachusetts medical centers on a biennial basis between 2001 and 2011. DAPT was defi

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14

Hou, Tianfei. "MECHANISMS AND POTENTIAL THERAPY ON DISRUPTED BLOOD PRESSURE CIRCADIAN RHYTHM IN DIABETES." UKnowledge, 2018. https://uknowledge.uky.edu/pharmacol_etds/26.

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Arterial blood pressure (BP) undergoes a 24-hour oscillation that peaks in the active day and reaches a nadir at night during sleep in humans. Reduced nocturnal BP fall (also known as non-dipper) is the most common disruption of BP circadian rhythm and is associated with increased risk of untoward cardiovascular events and target organ injury. Up to 75% of diabetic patients are non-dippers. However, the mechanisms underlying diabetes associated non-dipping BP are largely unknown. To address this important question, we generated a novel diabetic db/db-mPer2Luc mouse model (db/db-mPer2Luc) that

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15

Lopez, Johanna. "Correlates of Vitamin D Status in Healthy Older Adults Living in Miami-Dade and its Association with Non-Skeletal Outcomes: A Cross-Sectional Study." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/2256.

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Examining factors that affect vitamin D status in the fast-growing elderly population of Miami-Dade, Florida, is needed. Vitamin D deficiency in older adults has been linked to correlates of disability, including falls and fractures, and cardiovascular disease. The purpose of this study was to determine the proportion of vitamin D insufficient individuals and their relationship with vitamin D insufficiency in older adults (n=97) living in Miami-Dade. We evaluated the association between vitamin D status and 1) dual task physical performance to understand the link between vitamin D and cognitio

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16

Teixeira, Andrea Mariana Nunes da Costa. "Efeito da ingestão de chocolate e erva mate na elasticidade arterial de indivíduos com HIV/aids em terapia antirretroviral." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/6/6138/tde-11102013-103905/.

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Introdução - Estudos mostram maior ocorrência de complicações cardiovasculares na população HIV/aids. Alguns estudos envolvendo animais e indivíduos saudáveis ou com outras doenças observaram benefícios no consumo de chocolate e erva mate na função endotelial e vasodilatação. Objetivo Avaliar o efeito da ingestão de chocolate e erva mate na elasticidade arterial de indivíduos com HIV/aids em terapia antirretroviral. Métodos Ensaio clínico cruzado, aleatorizado e duplo-cego, envolvendo 89 indivíduos com HIV/aids entre 19 e 59 anos, em tratamento regular com antirretrovirais por no mínimo 6 me

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17

Lindgren, Peter. "Modeling the economics of prevention /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-352-3/.

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18

Tisminetzky, Mayra. "Modeling Co-Occurring Depression and Anxiety in Patients with an Acute Coronary Syndrome: A Dissertation." eScholarship@UMMS, 2009. https://escholarship.umassmed.edu/gsbs_diss/421.

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The purpose of the current project is to illustrate the application of advanced statistical techniques to address research questions about depression and anxiety in patients with an acute coronary syndrome (ACS). The first study, using data from 100 patients who were randomized into a clinical trial of cognitive behavioral therapy, used bivariate mixed models to determine trajectories of depression and anxiety after an ACS, to examine the effects of cognitive behavioral therapy (CBT) on depression and anxiety, and to determine if anxiety and depression symptoms change at the same rate with CBT

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19

Nogueira, Kátia Camarano. "Eficácia da sitagliptina no controle glicêmico e na função cardiovascular de pacientes portadores de diabetes mellitus tipo 2 tratados com metformina e glibenclamida." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/5/5135/tde-27072012-155318/.

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No tratamento do diabetes mellitus tipo 2, busca-se a otimização do controle glicêmico para evitar as complicações da doença. Quando a combinação mais utilizada (sulfoniluréia e biguanida) falha em manter o controle glicêmico, um terceiro agente é associado, podendo ser a insulina ou outro hipoglicemiante oral. O objetivo deste estudo foi comparar os efeitos da sitagliptina (droga inibidora da enzima dipeptidil-peptidase-4) com os da insulina NPH ao deitar, como terceira droga no tratamento do diabetes mellitus tipo 2, em pacientes inadequadamente controlados com glibenclamida e metformina. Tr

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20

Bruno, Maria Lucia Mendes. ""Três formas de intervenção para a adesão ao tratamento dietético da obesidade em cardiologia: estudo comparativo"." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-16102006-145427/.

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Trata-se de pesquisa realizada em hospital da rede pública estadual de São Paulo, especializado em cardiologia com pacientes obesos em acompanhamento ambulatorial pelo Serviço de Nutrição e Dietética (SND) dessa instituição. As formas de intervenção nutricional investigadas foram: atendimento individual, em grupo (controle) e grupo multiprofissional (com nutricionista e psicóloga). Na fase preliminar do estudo, realizou-se pesquisa de opinião que possibilitou o embasamento das variáveis analisadas. Na fase principal, os participantes foram divididos em grupos, sendo realizadas duas entrevistas

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21

Cutter, David J. "Radiation-related cardiovascular disease following cancer therapy." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:3f02ca87-530d-4ee7-9382-4b457bec62b5.

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<b><u>Introduction:</b></u> Some cancer survivors are known to have an elevated risk of morbidity and mortality from cardiovascular disease. An important cause of this elevated risk is recognised to be irradiation of normal tissues during radiotherapy received as part of cancer therapy. There are substantial difficulties in studying radiation-related cardiovascular disease (RRCD). The reasons for this include the complexities of measuring radiation normal tissue doses retrospectively and the prolonged latencies of many of the cardiovascular endpoints. A variety of complimentary research method

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22

Ormerod, Julian Oliver Macbeth. "Towards nitrite as a therapy in cardiovascular disease." Thesis, University of Birmingham, 2011. http://etheses.bham.ac.uk//id/eprint/3234/.

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The nitrite anion has traditionally been considered an inert by-product of nitric oxide (NO) metabolism, but is now thought to be an important source of bioactive NO. Work from our department and others have implicated intrinsic vascular wall heme-proteins in a hypoxia-potentiated release of NO. The experiments presented in this thesis were designed to test the hypothesis that vascular wall myoglobin is one of the responsible proteins, and furthermore that the release of NO in relative hypoxia may be useful therapeutically in conditions such as heart failure and myocardial ischaemia. Experimen

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23

Spivey, Justin, Heather Sirek, Robert Wood, Kalpit Devani, Billy Brooks, and Jonathan Moorman. "Retrospective Cohort Study of the Efficacy of Azithromycin Vs. Doxycycline as Part of Combination Therapy in Non-Intensive Care Unit Veterans Hospitalized with Community-Acquired Pneumonia." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/3177.

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The IDSA Community-Acquired Pneumonia (CAP) Guideline recommends ceftriaxone in combination with doxycycline as an alternative to combination therapy with ceftriaxone and azithromycin for non-intensive care unit (ICU) patients hospitalized with CAP. This is an attractive alternative regimen due to recent concerns of increased cardiovascular risk associated with azithromycin. The objective of this study was to compare the clinical outcomes of azithromycin and doxycycline each in combination with ceftriaxone for non-ICU Veterans hospitalized with CAP.

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24

Mayer, Kirby. "CHANGES IN MUSCLE SIZE, QUALITY AND POWER ARE RELATED TO PHYSICAL FUNCTION IN PATIENTS WITH CRITICAL ILLNESS." UKnowledge, 2019. https://uknowledge.uky.edu/rehabsci_etds/56.

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Patients admitted to intensive care unit (ICU) are known to develop significant impairments in physical function. Patients with critical illness suffer up to 30% reductions in muscle size within the first ten days of admission to the ICU. Muscle strength testing, Medical Research Council-sum score, is current gold-standard to diagnosis ICU-acquired weakness and predicts risk of mortality and long-term physical function. Muscle power different from muscle strength in that it accounts for velocity of movement, is potentially a better independent predictor of function that has not been studied in

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25

Xiu, Chun. "Inhibitory effect of Cryptotanshinone and Tanshinoe I on TNF-alpha-induced adhesion molecule expression in human umbilical vein endothelial cells." Thesis, University of Macau, 2008. http://umaclib3.umac.mo/record=b2162720.

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26

Denby, Laura. "Development of targeted gene therapy vectors for cardiovascular disease." Thesis, University of Glasgow, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422499.

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27

Nyamekye, Isaac. "Photodynamic therapy in the management of angioplasty restenosis." Thesis, University of Bristol, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294129.

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28

Pietrangelo, Maria G. "Antihypertensive therapy and risk of cardiovascular disease in diabetic subjects." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33822.

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Objective. This study was designed to assess the association between cardiovascular disease and the use of antihypertensive drugs in a diabetic population.<br>Design and setting. We conducted a case-control study nested within a cohort of 2499 subjects over 45 years old with diabetes and hypertension in Saskatchewan.<br>Outcomes. The main outcome measure was first hospitalization for cardiovascular disease.<br>Exposure definition. The main exposure of interest was current use of antihypertensive drugs, defined as drug dispensing within 90 days of the index date.<br>Statistical analysis. Relati

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Zacharowski, Kai. "Pathophysiology and therapy of myocardial infarction and reperfusion injury in rodents." Thesis, Queen Mary, University of London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325517.

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30

Bick, Alexander George. "At the Heart of the Genome: Rare Genetic Variation, Cardiovascular Disease, and Therapy." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11399.

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Studies of large families with inherited single gene disorders identified a role of rare genetic variation as a cause of disease and enabled gene-based diagnosis. The increasing availability of population-scale genomic sequencing implies the potential to extend gene-based diagnosis from individuals with monogenic disease to the prediction of disease risk in the general population. Cardiovascular disease (CVD), as a highly heritable condition with significant public health burden, represents an excellent place to consider the promise and limitations of extending our understanding of rare variat

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31

Queen, Jillian May. "Viral mediated gene transfer for modification of cell signalling and remodelling in the ischaemic myocardium." Thesis, University of Glasgow, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301367.

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32

Hsiao, Lien-Cheng. "Cardiac stem cell therapy for heart failure." Thesis, University of Oxford, 2012. https://ora.ox.ac.uk/objects/uuid:c4fcb449-2d05-4dc6-9a8d-f7450c0b200c.

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Cardiovascular disease is a leading cause of death worldwide and becomes increasingly prevalent in the elderly population. Independent of etiopathogenesis, heart failure (HF) is the final common stage of numerous heart diseases. Cardiac stem cell (CSC) therapy has emerged as a promising cell-based strategy for treatment of HF. However, cell replacement is not able to fully restore a structurally damaged myocardium in advanced and end-stage HF. The objective of this project was to test the following hypotheses: that a bioengineered heart extracellular matrix (ECM) with preserved intact geometri

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33

Cruz, Mayara Moura Alves da. "Efeitos da terapia baseada em realidade virtual sobre a motivação, engajamento, aderência e repercussões hemodinâmicas em cardiopatas." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/180585.

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Duncan, Ann Carolyn. "Hormone replacement therapy and vascular protection : the influence of oestrogen on the endothelium." Thesis, University of Glasgow, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.482821.

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35

Khanna, Vikram. "Assessment of individual responses to antiplatelet therapy in cardiovascular disease : insights with short thrombelastography." Thesis, University of Southampton, 2016. https://eprints.soton.ac.uk/415504/.

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The pivotal role of platelets in atherogenesis and thrombosis is well established. Consequently, suppression of platelet function with antiplatelet therapy (APT) is an important therapeutic target for the prevention of cardiovascular events in high-risk populations, particularly in patients treated with percutaneous coronary intervention (PCI). Based on various ex vivo platelet function assays (PFAs), studies have consistently shown heterogeneity in responses to APT. This is especially important given that platelet reactivity has been associated with both atherothrombotic events and bleeding c

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McMahon, Aisling Clare. "Myocardial dysfunction in experimental uraemia." Thesis, Queen Mary, University of London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264179.

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37

Podrebarac, James. "Development of Recombinant Human Collagen Type I and Type III Injectable Hydrogels for Cardiac Therapy." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36038.

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Functional biomaterials are being developed as scaffolds to support endogenous cells and to promote the regeneration of ischemic tissue. The aim for this study was to develop a new translational platform for injectable hydrogels using recombinant human collagen (rHC) of two types: type I (TI) and type III (TIII). The collagen solutions were characterized to ensure batch-to-batch consistency and protein integrity. The hydrogel preparation protocol was extensively monitored to ensure ease of use and high-quality production. Post-gelation, rHC TIII have a higher viscosity compared to rHC TI, yet

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Bossaer, John B., Stephen A. Geraci, and Kanishka Chakraborty. "Cardiovascular Toxicity and Management of Targeted Cancer Therapy: An Overview for Generalists." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/2324.

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The advent of effective oral, molecular-targeted drugs in oncology has changed many incurable malignancies such as chronic myeloid leukemia into chronic diseases similar to coronary artery disease and diabetes mellitus. Oral agents including monoclonal antibodies, kinase inhibitors and hormone receptor blockers offer cancer patients incremental improvements in both overall survival and quality of life. As it is imperative to recognize and manage side effects of platelet inhibitors, beta blockers, statins, HIV drugs, and fluoroquinolones by all healthcare providers, the same holds true for thes

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Ostojic, Aleksandra. "Use of a Collagen I Matrix to Enhance the Potential of Circulating Angiogenic Cells (CACs) for Therapy." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/31931.

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Acute myocardial infarction (MI) is the end result of many cardiovascular diseases and is one of the leading causes of death in the western world. Cell therapy, using circulating angiogenic cells (CACs) or CD34+ cells from peripheral blood, is one approach under investigation for restoring blood flow and function to the ischemic heart. However, the numbers of CACs and CD34+ circulating cells are inversely proportional to the severity of cardiovascular disease and age; therefore, there is a need to increase their numbers and/or function for therapy. One possibility is to enhance the therapeutic

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Tungsiripat, Marisa. "Changes in Peripheral Lipoatrophy, Surrogate Markers of Cardiovascular Disease, and Mitochondria after Rosiglitazone in HIV-infected individuals with Lipoatrophy." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1309964773.

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Galiyeva, Dinara. "Cardiovascular risk factor prevalence, mortality and cardiovascular disease incidence in patients who initiated renal replacement therapy in childhood : systematic review and analyses of two renal registries." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28837.

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Background. The incidence of starting renal replacement therapy (RRT) among young people (< 20 years of age) in 2013 in Scotland was 7.7 per million (age-related) population. Little knowledge exists about cardiovascular risk factors (CVRFs), long-term survival and cardiovascular disease (CVD) outcomes in patients who initiated RRT in childhood. The main source of routine data for these patients is available from the European Society of Paediatric Nephrology/European Renal Association- European Dialysis and Transplant Association (ESPN/ERA-EDTA) registry. In Scotland nationally comprehensive da

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Bruti, Gianpaolo. "Experimental and computational investigations for the development of intro-aortic balloon pump therapy." Thesis, Brunel University, 2016. http://bura.brunel.ac.uk/handle/2438/12476.

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Heart failure (HF) is a widely prevalent state in developing countries, especially among people over 65, with percentages up to 10% of the population in the US. In all developed countries the expenditure related to congestive heart failure consists of a high percentage of the total health care expenditure, reaching 60% in the UK (1991 1). One of the main strategies for dealing with HF is the use of cardiac assist devices. Among these the most widely used device is the Intra-Aortic balloon pump (IABP). The IABP has as the main aims to increase coronary flow during inflation, and decrease end di

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Curti, Fabiana. "Efeito da maçã gala (Malus domestica Borkh) na lipidemia de ratos hipercolesterolêmicos." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/11/11141/tde-18052004-165636/.

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Hábitos de vida saudáveis e uma dieta balanceada aliados ao alto consumo de frutas e vegetais, estão associados à prevenção de doenças e à manutenção da saúde. A maçã possui em sua composição compostos bioativos que podem agir na prevenção e no controle das dislipidemias. Tendo em vista a preocupação da Saúde Pública em encontrar uma fonte alternativa na redução das doenças cardiovasculares, esse trabalho teve como objetivo analisar a composição química da maçã, variedade Gala, e estudar os efeitos do seu consumo no ganho de peso, consumo alimentar, níveis sanguíneos de colesterol total, HDL-C

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Galarraga, Bernat. "Effect of anti-rheumatic therapy, folic acid supplementation and allopurinol on surrogate markers of cardiovascular disease in Rheumatoid arthritis." Thesis, University of Dundee, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505630.

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Casella, Ivan Benaduce. "Resultados do tratamento fibrinolítico da trombose venosa iliacofemoral por infusão seletiva de rt-PA em baixas doses." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-09102014-113205/.

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INTRODUÇÃO: A trombose venosa profunda é uma doença de alta incidência, e uma das principais causas de insuficiência venosa profunda. O tratamento clássico, com heparina e anticoagulante oral, não tem ação direta sobre o tempo de remoção do trombo. O tratamento trombolítico seletivo por cateter permite rápida remoção do coágulo com complicações inferiores a administração sistêmica do fibrinolítico. OBJETIVO: Comprovar a eficácia da infusão seletiva de rt-PA em baixas doses no tratamento da trombose venosa profunda iliacofemoral aguda e na prevenção do desenvolvimento dos sinais, sintomas e alt

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Nelson, DeAnn Lynn, and DeAnn Lynn Nelson. "Promoting the Use of Statin Therapy in Navajo Patients with Type 2 Diabetes." Diss., The University of Arizona, 2017. http://hdl.handle.net/10150/625670.

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Background: Type 2 diabetes mellitus (T2DM) is a major health concern among Navajo Indians. Native Americans and Alaskan Natives (NA/AN) currently have the highest rates of T2DM in the United States (Indian Health Service, 2016). The rate of diabetes on the Navajo Indian reservation is 22% (Partnersinhealth.org, 2009). Major health concerns for patients with T2DM include cardiovascular complications. Treatment is essential to prevent high-risk complications such as, cardiovascular disease (CVD). Purpose: The purpose of this quality improvement project was to implement a clinical decision sup

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PIETRABISSA, GIADA. ""MINDING THE HEART": fattori di rischio psicosociale e motivazione al cambiamento tra pazienti in riabilitazione cardiologica." Doctoral thesis, Università Cattolica del Sacro Cuore, 2016. http://hdl.handle.net/10280/10790.

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Il presente lavoro di tesi è stato condotto in ambito psicocardiologico, e riguarda l’indagine delle determinanti psicosociali potenzialmente coinvolte nell’eziopatogenesi, digressione e prognosi delle malattie cardiache. Più studi preliminari sono stati condotti a fini esplorativi, e solo le varabili risultate caratteristiche del campione mantenute in indagini successive. Dopo aver indagato il ruolo del benessere psicologico nell’influenzare la Capacità Funzionale dei pazienti, uno degli indicatori di esito di maggiore importanza in Riabilitazione Cardiologica (RC) (studio 1), si è proceduto

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Steiner-Boeker, Sabine. "Novel P2Y12 Receptor Antagonists - Prasugrel and Ticagrelor. Systematic Review, Indirect Comparison to Clopidogrel in Cardiovascular Disease, Design of a Randomized Controlled Trial." Thesis, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20176.

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Antiplatelet therapy with clopidogrel is widely used in patients with coronary artery disease, but the recent development of the new P2Y12 receptor antagonists prasugrel and ticagrelor will increase treatment options. An overview of systematic reviews was performed to summarize available evidence on clopidogrel. Current data on prasugrel and ticagrelor were identified by a systematic review and used for an indirect treatment comparison (ITC) of the drugs against each other and versus placebo in the absence of head-to-head clinical trials. Adjusted indirect comparison according to Bucher, Bayes

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Dane-Stewart, Cheryl Ann. "Postprandial lipoprotein metabolism in patients at high risk of coronary artery disease : effects of statin therapy." University of Western Australia. School of Medicine and Pharmacology, 2003. http://theses.library.uwa.edu.au/adt-WU2004.0061.

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[Formulae and special characters can only be approximated here. Please see the pdf version of the abstract for an accurate reproduction.] Atherosclerosis is a common degenerative disease in which the clinical manifestations are often through stroke or myocardial infarction. Some of the established risk factors for atherosclerosis include elevated plasma low-density lipoprotein (LDL)-cholesterol levels, obesity, diabetes mellitus (DM) and cigarette smoking. Of the risk factors, an elevation in plasma LDL is one of the most established and the most researched. This is partly a consequence of

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Arias-Loza, Anahi-Paula. "Hormone Replacement Therapy and cardiovascular disease : Differential effects of the regimes Medroxyprogesterone Acetate plus 17-Beta- estradiol and unopposed 17-Beta- estradiol." kostenfrei, 2008. http://www.opus-bayern.de/uni-wuerzburg/volltexte/2008/2766/.

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