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Journal articles on the topic 'Cargo compartment'

Author: Grafiati

Published: 30 May 2022

Last updated: 31 July 2025

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1

Kou, Hongfei. "Research on Testing and Calculation Analysis of Cargo Bay Fire-Extinguishing Agent Concentration Based on Different Loading in Civil Aircraft." Journal of Physics: Conference Series 2410, no. 1 (2022): 012002. http://dx.doi.org/10.1088/1742-6596/2410/1/012002.

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Abstract In the history of international aviation, there have been many fire accidents of the cargo compartment. To ensure that the fire is extinguished in time when the cargo compartment is on fire, and to ensure the safety of aircraft and personnel, the design of the cargo compartment fire extinguishing system needs to be verified according to CCAR 25. According to the AC851-1 guidance, the verification of the cargo compartment's fire extinguishing system design aims to test and calculate the concentration of fire extinguishing agents used for the C-class cargo compartment based on different

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Kalaidzidis, Inna, Marta Miaczynska, Marta Brewińska-Olchowik, et al. "APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments." Journal of Cell Biology 211, no. 1 (2015): 123–44. http://dx.doi.org/10.1083/jcb.201311117.

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Endocytosis allows cargo to enter a series of specialized endosomal compartments, beginning with early endosomes harboring Rab5 and its effector EEA1. There are, however, additional structures labeled by the Rab5 effector APPL1 whose role in endocytic transport remains unclear. It has been proposed that APPL1 vesicles are transport intermediates that convert into EEA1 endosomes. Here, we tested this model by analyzing the ultrastructural morphology, kinetics of cargo transport, and stability of the APPL1 compartment over time. We found that APPL1 resides on a tubulo-vesicular compartment that

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Гребеников, А. Г., А. З. Двейрин та Д. С. Конышев. "ПРОЕКТУВАННЯ СТУЛКОВОГО ВІДСІКУ ХВОСТОВИХ ВАНТАЖНИХ ЛЮКІВ ЛІТАКІВ ТРАНСПОРТНОЇ КАТЕГОРІЇ". Open Information and Computer Integrated Technologies, № 93 (19 листопада 2021): 27–58. http://dx.doi.org/10.32620/oikit.2021.93.03.

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The method for determining the main parameters of the tail cargo doors of transport category aircraft is developed. There have been prepared initial data and described the methodology for finding them. An example based on an existing transport aircraft is considered. The basic nomenclature of transported cargoes of the designed aircraft, its dimensions and weight, methods of loading and mooring, additional loading equipment were taken as initial data. As well as such necessary design, operational and regulatory parameters and data as landing gear type, its “kneeling” system, rails of the upper

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Zhu, Pei, Ziheng Xu, Jiangao Zhang, Quan Shao, Weiwang Chen, and Hongzhou Ai. "Numerical Study on Fire Suppression by Water Mist in Aircraft Cargo Compartments: Effects of Spray Pattern, Droplet Size, and Nozzle Layout." Fire 7, no. 12 (2024): 481. https://doi.org/10.3390/fire7120481.

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Aircraft cargo compartment fires are one of the main threats to the safety of civil aircraft. In this study, a series of numerical simulations on the fire suppression performance of water mist in cargo compartments was carried out to examine the effects of the spray pattern, droplet size, and nozzle layout. The fire dynamics simulator (FDS) code was used to construct a fire suppression scenario in a full-scale aircraft cargo compartment. The results show that the extinguishment time of a corner fire was longer compared with center and sidewall fires due to the relatively larger distance from t

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Peng, Yang, Pu Wang, Xiaolong Zhao, Meilin Chen, Jun Zhang, and Fan Zhang. "A data-driven air cargo redistribution model based on multiple programming." International Journal of Modern Physics B 33, no. 17 (2019): 1950176. http://dx.doi.org/10.1142/s0217979219501765.

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Air cargo transportation is an essential mode of cargo transportation. How to distribute air cargo into flights better is an important operational problem. In this paper, air cargo data collected by CAAC (Civil Aviation Administration of China) during the first three months of 2018 are analyzed. We find that the available capacity for cargo transportation shows great variations, and the cargo compartment utilization rates of flights are heterogeneously distributed. Next, a data-driven air cargo redistribution model is developed based on multiple programming (MP). The proposed model can effecti

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Styers, Melanie L., Amber K. O'Connor, Robert Grabski, Estelle Cormet-Boyaka та Elizabeth Sztul. "Depletion of β-COP reveals a role for COP-I in compartmentalization of secretory compartments and in biosynthetic transport of caveolin-1". American Journal of Physiology-Cell Physiology 294, № 6 (2008): C1485—C1498. http://dx.doi.org/10.1152/ajpcell.00010.2008.

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We have utilized small interfering RNA (siRNA)-mediated depletion of the β-COP subunit of COP-I to explore COP-I function in organellar compartmentalization and protein traffic. Reduction in β-COP levels causes the colocalization of markers for the endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC), Golgi, trans-Golgi network (TGN), and recycling endosomes in large, globular compartments. The lack of spatial differentiation of these compartments is not due to a general collapse of all cellular organelles since markers for the early endosomes and lysosomes do not redistribute to

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Saraste, Jaakko, and Bruno Goud. "Functional Symmetry of Endomembranes." Molecular Biology of the Cell 18, no. 4 (2007): 1430–36. http://dx.doi.org/10.1091/mbc.e06-10-0933.

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In higher eukaryotic cells pleiomorphic compartments composed of vacuoles, tubules and vesicles move from the endoplasmic reticulum (ER) and the plasma membrane to the cell center, operating in early biosynthetic trafficking and endocytosis, respectively. Besides transporting cargo to the Golgi apparatus and lysosomes, a major task of these compartments is to promote extensive membrane recycling. The endocytic membrane system is traditionally divided into early (sorting) endosomes, late endosomes and the endocytic recycling compartment (ERC). Recent studies on the intermediate compartment (IC)

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Ayloo, Swathi, Pedro Guedes-Dias, Amy E. Ghiretti, and Erika L. F. Holzbaur. "Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes." Molecular Biology of the Cell 28, no. 19 (2017): 2543–54. http://dx.doi.org/10.1091/mbc.e17-01-0068.

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The efficient transport of cargoes within axons and dendrites is critical for neuronal function. Although we have a basic understanding of axonal transport, much less is known about transport in dendrites. We used an optogenetic approach to recruit motor proteins to cargo in real time within axons or dendrites in hippocampal neurons. Kinesin-1, a robust axonal motor, moves cargo less efficiently in dendrites. In contrast, cytoplasmic dynein efficiently navigates both axons and dendrites; in both compartments, dynamic microtubule plus ends enhance dynein-dependent transport. To test the predict

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Carlson, Nathan J., Adam D. Reiman, Robert E. Overstreet, and Matthew A. Douglas. "Load planning processes to enhance cargo compartment utilization." Journal of Defense Analytics and Logistics 1, no. 2 (2017): 137–50. http://dx.doi.org/10.1108/jdal-07-2017-0011.

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Purpose The United States Air Force often provides effective airlift for cargo distribution, but is at times inefficient. This paper aims to address the under-utilization of military airlift cargo compartments that plagues the airlift system. Design/methodology/approach The authors examine seven techniques designed to increase cargo compartment utilization and increase airlift utilization rates. The techniques were applied through load planning software to 30 real-world movements consisting of 159 sorties. They then ran each post-technique movement through a modeled flight environment to obtai

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Heinrich, Reinhart, and Tom A. Rapoport. "Generation of nonidentical compartments in vesicular transport systems." Journal of Cell Biology 168, no. 2 (2005): 271–80. http://dx.doi.org/10.1083/jcb.200409087.

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How can organelles communicate by bidirectional vesicle transport and yet maintain different protein compositions? We show by mathematical modeling that a minimal system, in which the basic variables are cytosolic coats for vesicle budding and membrane-bound soluble N-ethyl-maleimide–sensitive factor attachment protein receptors (SNAREs) for vesicle fusion, is sufficient to generate stable, nonidentical compartments. A requirement for establishing and maintaining distinct compartments is that each coat preferentially packages certain SNAREs during vesicle budding. Vesicles fuse preferentially

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Vetho Tigelrito, Freddy Franciscus, and Bismil Rabeta. "Analisis Aplikasi Coating Pada Roller Track Cargo Compartment Pada Airbus 330-200/300." Jurnal Teknologi Kedirgantaraan 7, no. 2 (2022): 99–109. http://dx.doi.org/10.35894/jtk.v7i2.59.

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Aircaft are the most popular means of transportation in the delivery of goods from one area to another. These things can be inaminate objects or living things. Goods transported to the cargo area can be a trigger for damage to the cargo area of the Airbus 330 aircraft, such as spilling fluid from the cargo packaging and the loading process or unloading cargo can cause corrosion in the cargo areaRoller track cargo compartment is one part of the aircraft that is susceptible to corrosion. In aircraft maintenance manual there is no step to apply coating application, where it is known that the coat

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Nothwehr, Steven F., Seon-Ah Ha, and Paul Bruinsma. "Sorting of Yeast Membrane Proteins into an Endosome-to-Golgi Pathway Involves Direct Interaction of Their Cytosolic Domains with Vps35p." Journal of Cell Biology 151, no. 2 (2000): 297–310. http://dx.doi.org/10.1083/jcb.151.2.297.

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Resident late-Golgi membrane proteins in Saccharomyces cerevisiae are selectively retrieved from a prevacuolar–endosomal compartment, a process dependent on aromatic amino acid–based sorting determinants on their cytosolic domains. The formation of retrograde vesicles from the prevacuolar compartment and the selective recruitment of vesicular cargo are thought to be mediated by a peripheral membrane retromer protein complex. We previously described mutations in one of the retromer subunit proteins, Vps35p, which caused cargo-specific defects in retrieval. By genetic and biochemical means we no

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SZYMKIEWICZ, Iwona, Oleg SHUPLIAKOV, and Ivan DIKIC. "Cargo- and compartment-selective endocytic scaffold proteins." Biochemical Journal 383, no. 1 (2004): 1–11. http://dx.doi.org/10.1042/bj20040913.

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The endocytosis of membrane receptors is a complex and tightly controlled process that is essential for maintaining cellular homoeostasis. The removal of receptors from the cell surface can be constitutive or ligand-induced, and occurs in a clathrin-dependent or -independent manner. The recruitment of receptors into specialized membrane domains, the formation of vesicles and the trafficking of receptors together with their ligands within endocytic compartments are regulated by reversible protein modifications, and multiple protein–protein and protein–lipid interactions. Recent reports describe

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Gomez-Navarro, Natalia, and Elizabeth Miller. "Protein sorting at the ER–Golgi interface." Journal of Cell Biology 215, no. 6 (2016): 769–78. http://dx.doi.org/10.1083/jcb.201610031.

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Protein traffic is of critical importance for normal cellular physiology. In eukaryotes, spherical transport vesicles move proteins and lipids from one internal membrane-bound compartment to another within the secretory pathway. The process of directing each individual protein to a specific destination (known as protein sorting) is a crucial event that is intrinsically linked to vesicle biogenesis. In this review, we summarize the principles of cargo sorting by the vesicle traffic machinery and consider the diverse mechanisms by which cargo proteins are selected and captured into different tra

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Cui, Hongwei, Chenran Ruan, Shengdong Wang, Song Lu, Heping Zhang, and Minqiang Wang. "Study on Response Time Hysteresis Model of Smoke Detectors in Aircraft Cargo Compartment." Fire 7, no. 9 (2024): 317. http://dx.doi.org/10.3390/fire7090317.

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A fire in the cargo compartment has a major impact on civil aviation flight safety, and according to the airworthiness clause of the CCAR-25, the detector must sound an alarm within 1 min of a fire in the cargo compartment. As for the cargo compartment of large transport aircrafts, the internal space is high and open, and the smoke movement speed becomes slower with significant cooling in the process of diffusion. Hysteresis can occur in smoke detectors because of their internal labyrinth structure, which causes the detector’s internal and external response signals to be out of sync. This rese

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Nindhia, Tjokorda Gde Tirta Tirta, and Yoseferio Murti Gunawan. "Studi Rekayasa Manufaktur dan Perakitan Cargo Door pada Pesawat Cargo." Jurnal Pendidikan Teknik Mesin Undiksha 13, no. 1 (2025): 96–107. https://doi.org/10.23887/jptm.v13i1.84066.

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Zaman sekarang banyak sekali transportasi umum yang tersedia baik dari pemerintah maupun swasta, dan salah satunya adalah pesawat. Pesawat adalah salah satu moda transportasi umum yang digemari dan dibutuhkan oleh masyarakat, karena pesawat merupakan transportasi umum nomor satu di dunia, dengan alasan kenyamanan dan kecepatan. Dengan berkembangnya teknologi maka pesawat pun juga tak mau ketinggalan. Pesawat penumpang akan semakin besar dan canggih seiring berjalannya waktu. Perkembangan teknologi pada pesawat diperlukan untuk memenuhi kebutuhan penumpang. Pesawat banyak dikenal sebagai sarana

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Delgadillo, María Otilia, Guillermo Ruano, Jan Zouhar, et al. "MTV proteins unveil ER- and microtubule-associated compartments in the plant vacuolar trafficking pathway." Proceedings of the National Academy of Sciences 117, no. 18 (2020): 9884–95. http://dx.doi.org/10.1073/pnas.1919820117.

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The factors and mechanisms involved in vacuolar transport in plants, and in particular those directing vesicles to their target endomembrane compartment, remain largely unknown. To identify components of the vacuolar trafficking machinery, we searched for Arabidopsis modified transport to the vacuole (mtv) mutants that abnormally secrete the synthetic vacuolar cargo VAC2. We report here on the identification of 17 mtv mutations, corresponding to mutant alleles of MTV2/VSR4, MTV3/PTEN2A MTV7/EREL1, MTV8/ARFC1, MTV9/PUF2, MTV10/VPS3, MTV11/VPS15, MTV12/GRV2, MTV14/GFS10, MTV15/BET11, MTV16/VPS51

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Madappa, Eshwari A., M. V. Sankalp Reddy, Rajaneesh R, Shashank A S, and Sudeep S. Kodad. "Encrypt Express: Security Enhancement, Maximizing Load Utilization in Cargo Transport through IoT and Algorithmic Solutions." International Journal of Emerging Science and Engineering 12, no. 8 (2024): 20–26. http://dx.doi.org/10.35940/ijese.e4490.12080724.

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The Encrypt Express model revolutionizes cargo logistics by leveraging IoT technology to improve safety, security, and efficiency. It integrates the DHT11 sensor to monitor environmental conditions such as temperature and humidity, ensuring optimal storage of goods. Using one-time password (OTP) access for the doors significantly enhances security, while the cargo compartment is divided into two slots for better cargo management. The features of the model include distance-based pricing, optimizing costs based on journey length. To improve user experience and tracking, an intuitive user interfa

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Zhang, Huan. "Design Method of the Civil Aircraft Cargo Compartment Interiors Based on Resist-flame Burnthrough." Journal of Physics: Conference Series 2561, no. 1 (2023): 012014. http://dx.doi.org/10.1088/1742-6596/2561/1/012014.

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Abstract This paper aims to conduct research on interior design methods based on resist-flame burn-through. The paper first analyzed the acceptance criterion of the oil burner test according to part III of Appendix F, part 25, [1]. Then it elaborated on various design methods of cargo compartment liners combined with the previous design and test experience, including the design method of material, opening features, lap/butt joint features, and corner butt joint features [2]. These design methods can effectively improve the ability to resist-flame burn-through of cargo compartment liners.

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Mukhopadhyay, Aparna, Jose A. Quiroz, and Allan W. Wolkoff. "Rab1a regulates sorting of early endocytic vesicles." American Journal of Physiology-Gastrointestinal and Liver Physiology 306, no. 5 (2014): G412—G424. http://dx.doi.org/10.1152/ajpgi.00118.2013.

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We previously reported that Rab1a is associated with asialoorosomucoid (ASOR)-containing early endocytic vesicles, where it is required for their microtubule-based motility. In Rab1a knockdown (KD) cell lines, ASOR failed to segregate from its receptor and, consequently, did not reach lysosomes for degradation, indicating a defect in early endosome sorting. Although Rab1 is required for Golgi/endoplasmic reticulum trafficking, this process was unaffected, likely due to retained expression of Rab1b in these cells. The present study shows that Rab1a has a more general role in endocytic vesicle p

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Stewart, Murray. "Function of the Nuclear Transport Machinery in Maintaining the Distinctive Compositions of the Nucleus and Cytoplasm." International Journal of Molecular Sciences 23, no. 5 (2022): 2578. http://dx.doi.org/10.3390/ijms23052578.

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Although the separation of transcription and translation, mediated by the nuclear envelope, is the defining characteristic of Eukaryotes, the barrier between the nuclear and cytoplasmic compartments needs to be semipermeable to enable material to be moved between them. Moreover, each compartment needs to have a distinctive complement of macromolecules to mediate specific functions and so movement between them needs to be controlled. This is achieved through the selective active transport of macromolecules through the nuclear pores that stud the nuclear envelope, and which serve as a conduit be

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Rajaneesh, R. "Encrypt Express: Security Enhancement, Maximizing Load Utilization in Cargo Transport through IoT and Algorithmic Solutions." International Journal of Emerging Science and Engineering (IJESE) 12, no. 8 (2024): 20–26. https://doi.org/10.35940/ijese.E4490.12080724.

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<strong>Abstract:</strong> The Encrypt Express model revolutionizes cargo logistics by leveraging IoT technology to improve safety, security, and efficiency. It integrates the DHT11 sensor to monitor environmental conditions such as temperature and humidity, ensuring optimal storage of goods. Using one-time password (OTP) access for the doors significantly enhances security, while the cargo compartment is divided into two slots for better cargo management. The features of the model include distance-based pricing, optimizing costs based on journey length. To improve user experience and tracking

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23

Xie, Shuwei, Kriti Bahl, James B. Reinecke, Gerald R. V. Hammond, Naava Naslavsky, and Steve Caplan. "The endocytic recycling compartment maintains cargo segregation acquired upon exit from the sorting endosome." Molecular Biology of the Cell 27, no. 1 (2016): 108–26. http://dx.doi.org/10.1091/mbc.e15-07-0514.

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The endocytic recycling compartment (ERC) is a series of perinuclear tubular and vesicular membranes that regulates recycling to the plasma membrane. Despite evidence that cargo is sorted at the early/sorting endosome (SE), whether cargo mixes downstream at the ERC or remains segregated is an unanswered question. Here we use three-dimensional (3D) structured illumination microscopy and dual-channel and 3D direct stochastic optical reconstruction microscopy (dSTORM) to obtain new information about ERC morphology and cargo segregation. We show that cargo internalized either via clathrin-mediated

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Coonrod, Emily M., and Tom H. Stevens. "The Yeast vps Class E Mutants: The Beginning of the Molecular Genetic Analysis of Multivesicular Body Biogenesis." Molecular Biology of the Cell 21, no. 23 (2010): 4057–60. http://dx.doi.org/10.1091/mbc.e09-07-0603.

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In 1992, Raymond et al. published a compilation of the 41 yeast vacuolar protein sorting (vps) mutant groups and described a large class of mutants (class E vps mutants) that accumulated an exaggerated prevacuolar endosome-like compartment. Further analysis revealed that this “class E compartment” contained soluble vacuolar hydrolases, vacuolar membrane proteins, and Golgi membrane proteins unable to recycle back to the Golgi complex, yet these class E vps mutants had what seemed to be normal vacuoles. The 13 class E VPS genes were later shown to encode the proteins that make up the complexes

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Macara, Ian G. "Transport into and out of the Nucleus." Microbiology and Molecular Biology Reviews 65, no. 4 (2001): 570–94. http://dx.doi.org/10.1128/mmbr.65.4.570-594.2001.

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SUMMARY A defining characteristic of eukaryotic cells is the possession of a nuclear envelope. Transport of macromolecules between the nuclear and cytoplasmic compartments occurs through nuclear pore complexes that span the double membrane of this envelope. The molecular basis for transport has been revealed only within the last few years. The transport mechanism lacks motors and pumps and instead operates by a process of facilitated diffusion of soluble carrier proteins, in which vectoriality is provided by compartment-specific assembly and disassembly of cargo-carrier complexes. The carriers

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Фролов, Виктор Петрович, та Дмитрий Васильевич Клименко. "АВІАЦІЙНЕ ТРАНСПОРТУВАННЯ РІДИННИХ РАКЕТ-НОСІЇВ". Aerospace Technic and Technology, № 2 (25 березня 2017): 22–25. http://dx.doi.org/10.32620/aktt.2017.2.02.

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This paper concerns the problem of liquid propellant launch vehicles delivery to the launch center. The variants of launch vehicles transportation using rail, road and air transport were considered. The key problems of transportation using the aircrafts, such as overloads applied to the launch vehicle attake off and landing, variation of temperature inside the aircraft cargo compartment, difference in pressure inside the launch vehicle propellant tank sand aircraft cargo compartment, were studied. As a result the proposals for avoiding such problems at transportation using aircraft were stated

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Lu, Tiancheng, and Xiaoliang Lu. "Civil Aircraft Passenger-to-Freighter Main Cargo Compartment lining Validation Technology." Advances in Computer and Engineering Technology Research 1, no. 1 (2023): 79. http://dx.doi.org/10.61935/acetr.1.1.2023.p79.

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Passenger-to-freighter conversion is a common practice in the aviation industry, especially for older civil aircraft that have completed their passenger service missions. Converting these aircraft into freighters extends their operational lifespan by several years, significantly increasing the overall economic benefits throughout their life-cycle. The main cargo compartment lining is a crucial component of the P2F conversion process, It must meet the requirements outlined in CCAR-25. This paper, based on experiences in civil aircraft Passenger-to-freighter conversions, examines the CCAR-25 reg

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Robertson, Sarah E., Subba Rao Gangi Setty, Anand Sitaram, Michael S. Marks, Robert E. Lewis, and Margaret M. Chou. "Extracellular Signal-regulated Kinase Regulates Clathrin-independent Endosomal Trafficking." Molecular Biology of the Cell 17, no. 2 (2006): 645–57. http://dx.doi.org/10.1091/mbc.e05-07-0662.

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Extracellular signal-regulated kinase (Erk) is widely recognized for its central role in cell proliferation and motility. Although previous work has shown that Erk is localized at endosomal compartments, no role for Erk in regulating endosomal trafficking has been demonstrated. Here, we report that Erk signaling regulates trafficking through the clathrin-independent, ADP-ribosylation factor 6 (Arf6) GTPase-regulated endosomal pathway. Inactivation of Erk induced by a variety of methods leads to a dramatic expansion of the Arf6 endosomal recycling compartment, and intracellular accumulation of

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Xu, Dalu, and Jesse C. Hay. "Reconstitution of COPII vesicle fusion to generate a pre-Golgi intermediate compartment." Journal of Cell Biology 167, no. 6 (2004): 997–1003. http://dx.doi.org/10.1083/jcb.200408135.

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What is the first membrane fusion step in the secretory pathway? In mammals, transport vesicles coated with coat complex (COP) II deliver secretory cargo to vesicular tubular clusters (VTCs) that ferry cargo from endoplasmic reticulum exit sites to the Golgi stack. However, the precise origin of VTCs and the membrane fusion step(s) involved have remained experimentally intractable. Here, we document in vitro direct tethering and SNARE-dependent fusion of endoplasmic reticulum–derived COPII transport vesicles to form larger cargo containers. The assembly did not require detectable Golgi membran

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Li, Zitong, Yuanhua He, Jingdong Wang, and Jiang Huang. "Flashover Features in Aircraft Cargo Compartment at Low Pressure." Fire 7, no. 10 (2024): 350. http://dx.doi.org/10.3390/fire7100350.

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The flashover mechanism in an aircraft cargo compartment under low pressure was investigated in this study. A series of fire experiments were conducted in a scale model of a one-quarter volume FAA standard aircraft cargo compartment at 96 kPa and 60 kPa. The ignition of single-walled corrugated cardboard was chosen as the criterion of the flashover. The influence of different fire sizes and fuel types on the flashover was studied by comparing the average temperature of the smoke layer, the radiation heat flux at the floor level, and the heat release rate of the fire source. The critical condit

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Loiseau, Eve, Patrick A. Rühs, Alina Hauser, Fabian Niedermair, Gerhard Albrecht, and André R. Studart. "Strong Dual-Compartment Microcapsules Loaded with High Cargo Contents." Langmuir 34, no. 1 (2017): 205–12. http://dx.doi.org/10.1021/acs.langmuir.7b03232.

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Blake, David, and Jill Suo-Anttila. "Aircraft cargo compartment fire detection and smoke transport modeling." Fire Safety Journal 43, no. 8 (2008): 576–82. http://dx.doi.org/10.1016/j.firesaf.2008.01.003.

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Sakre, Mohin M., Dhiraj Jhamb, Manohar Dutt, and S. D. Mukul. "C130J: IAF’s Hercules in casualty/medical evacuation." Indian Journal of Aerospace Medicine 67 (August 2, 2024): 46–53. http://dx.doi.org/10.25259/ijasm_19_2023.

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Objectives: This study looks to evaluate the casualty/medical evacuation capabilities of the Indian Air Force’s formidable C130J-30 in terms of patient carrying capacity patient support facility while also assessing its aeromedical issues. Material and Methods: This descriptive report employs a detailed and analytical evaluation of an on-ground parked C130J-30 Super Hercules. In addition, manuals have been referred to; data have been inferred from real-life experiences, and drills and inputs from the aircrew through interview methods have been incorporated. Results: The C130J has a seated casu

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Xiong, Yifang, Michail Diakostefanis, Akhil Dinesh, Suresh Sampath, and Theoklis Nikolaidis. "Numerical assessment for aircraft cargo compartment fire suppression system safety." Journal of Fire Sciences 39, no. 3 (2021): 240–61. http://dx.doi.org/10.1177/07349041211003208.

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Fire on board an aircraft cargo compartment can lead to catastrophic consequences. Therefore, fire safety is one of the most important considerations during aircraft design and certification. Conventionally, Halon-based agents were used for fire suppression in such cases. However, an international agreement under the Montreal Protocol of 1994 banned further production of Halon and several other halocarbons considered harmful to the environment. There is therefore a requirement for new suppression agents, along with suitable system design and certification. This article aims to describe the cre

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Jiang, Xuan. "Experimental Study on Rapid Pressure Relief in the Cargo Compartment of Civil Aircraft." Advances in Engineering Technology Research 1, no. 2 (2022): 286. http://dx.doi.org/10.56028/aetr.1.2.286.

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The rapid pressure relief device in the cargo compartment of civil aircraft can avoid the structural damage of aircraft caused by sudden pressure relief in a pressurized compartment. Based on a typical rapid pressure relief device in the cargo hold of civil aircraft, a test bench was built to carry out experimental research on the pressure magnitude and pressure relief process of the device. To simulate the real pressure relief situation of the aircraft pressurized cabin, two experimental studies of forwarding pressure and reverse pressure were carried out, and the pressure relief process of t

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Jiang, Xuan. "Experimental Study on Rapid Pressure Relief in the Cargo Compartment of Civil Aircraft." Advances in Engineering Technology Research 2, no. 1 (2022): 286. http://dx.doi.org/10.56028/aetr.2.1.286.

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The rapid pressure relief device in the cargo compartment of civil aircraft can avoid the structural damage of aircraft caused by sudden pressure relief in a pressurized compartment. Based on a typical rapid pressure relief device in the cargo hold of civil aircraft, a test bench was built to carry out experimental research on the pressure magnitude and pressure relief process of the device. To simulate the real pressure relief situation of the aircraft pressurized cabin, two experimental studies of forwarding pressure and reverse pressure were carried out, and the pressure relief process of t

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Sonnenschein, Richard J., and Chi-Cheng Yang. "One-Compartment Damage Survivability Versus 1992 IMO Probabilistic Damage Criteria for Dry Cargo Ships." Marine Technology and SNAME News 30, no. 01 (1993): 3–27. http://dx.doi.org/10.5957/mt1.1993.30.1.3.

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No international or U.S. Coast Guard requirements for the damage survival of dry cargo ships existed until February 1992, when an international, probabilistic damage standard for dry cargo ships was adopted by the International Maritime Organization (IMO) and the U.S. Coast Guard. A deterministic one-compartment damage standard has been applied to most U.S.-flag dry cargo ships built since 1937, either voluntarily or as a requirement for Federal assistance under the Maritime Administration. Despite some of its inherent deficiencies, it appears that the one-compartment standard has invariably r

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Zhang, Zhen. "Design of Cargo Hold Ventilation Electrical System for PCTC." International Journal of Mechanical and Electrical Engineering 3, no. 3 (2024): 26–30. http://dx.doi.org/10.62051/ijmee.v3n3.04.

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The design of the PCTC cargo compartment ventilation system is an important system in the overall PCTC ship design, which is related to the design of multiple specialties such as general, structure, outfitting, machinery and electrical section. In recent years, the design of the cargo hold ventilation system for PCTC ships has also been constantly changing, improving, and optimizing. This article summarizes and optimizes the current mainstream design schemes for the electrical system of PCTC cargo hold ventilation, taking into account both the construction cost of the shipyard and the operatin

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Papa, Ramon, Cláudia R. Andrade, Edson L. Zaparoli, and Luis C. de C. Santos. "CFD analysis of smoke transport inside an aircraft cargo compartment." Journal of the Brazilian Society of Mechanical Sciences and Engineering 38, no. 2 (2015): 327–34. http://dx.doi.org/10.1007/s40430-015-0307-7.

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Mirtabaei, Seyed Mostafa, and Seyed Amirhossein Ahmadi. "Vibration optimisation of truck cargo transport compartment using numerical simulation." International Journal of Heavy Vehicle Systems 32, no. 2 (2025): 228–43. https://doi.org/10.1504/ijhvs.2025.145129.

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Ludwig, Nils, Theresa L. Whiteside, and Torsten E. Reichert. "Challenges in Exosome Isolation and Analysis in Health and Disease." International Journal of Molecular Sciences 20, no. 19 (2019): 4684. http://dx.doi.org/10.3390/ijms20194684.

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A growing body of evidence emphasizes the important role exosomes in different physiological and pathological conditions. Exosomes, virus-size extracellular vesicles (EVs), carry a complex molecular cargo, which is actively processed in the endocytic compartment of parental cells. Exosomes carry and deliver this cargo to recipient cells, serving as an intercellular communication system. The methods for recovery of exosomes from supernatants of cell lines or body fluids are not uniformly established. Yet, studies of the quality and quantity of exosome cargos underlie the concept of “liquid biop

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Jafaryeganeh, Hamidreza, Manuel Ventura, and Carlos Guedes Soares. "Multi-Objective Optimization of Internal Compartment Layout of Oil Tankers." Journal of Ship Production and Design 35, no. 4 (2019): 374–85. http://dx.doi.org/10.5957/jspd.09180034.

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This work deals with the design of the internal layout of a shuttle tanker formulated as a multi-objective optimization problem, balancing cargo capacity and minimizing still water bending moment with safety requirements, in particular survivability after damage. A parametric model is used to specify the internal layout of a tanker ship considering a fixed hull shape and regulatory framework. The design variables include positions of watertight members in the internal layout, such as watertight bulkhead position, double-bottom height, and wing tanks width. Merit functions are the minimization

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Barroso, M., and ES Sztul. "Basolateral to apical transcytosis in polarized cells is indirect and involves BFA and trimeric G protein sensitive passage through the apical endosome." Journal of Cell Biology 124, no. 1 (1994): 83–100. http://dx.doi.org/10.1083/jcb.124.1.83.

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We have used temperature and nocodazole blocks in an in vivo basolateral to apical transcytosis assay to dissociate the early transcytotic steps occurring during the formation of transcytotic vesicles and their microtubule-dependent translocation into the apical region, from the late steps when transcytotic cargo is delivered into the apical media. We found that polarized MDCK cells transfected with rabbit polymeric IgA receptor (pIgA-R) internalize basolaterally added pIgA-R ligand ([Fab]2 fragment of IgG against the receptor's ectodomain) at 17 degrees C but do not deliver it to the apical P

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Sabido-Bozo, Susana, Ana Maria Perez-Linero, Javier Manzano-Lopez, et al. "The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection." International Journal of Molecular Sciences 22, no. 1 (2021): 423. http://dx.doi.org/10.3390/ijms22010423.

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Golgi trafficking depends on the small GTPase Arf1 which, upon activation, drives the assembly of different coats onto budding vesicles. Two related types of guanine nucleotide exchange factors (GEFs) activate Arf1 at different Golgi sites. In yeast, Gea1 in the cis-Golgi and Gea2 in the medial-Golgi activate Arf1 to form COPIcoated vesicles for retrograde cargo sorting, whereas Sec7 generates clathrin/adaptorcoated vesicles at the trans-Golgi network (TGN) for forward cargo transport. A central question is how the same activated Arf1 protein manages to assemble different coats depending on

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Messenger, Scott W., Diana D. H. Thomas, Michelle A. Falkowski, Jennifer A. Byrne, Fred S. Gorelick, and Guy E. Groblewski. "Tumor protein D52 controls trafficking of an apical endolysosomal secretory pathway in pancreatic acinar cells." American Journal of Physiology-Gastrointestinal and Liver Physiology 305, no. 6 (2013): G439—G452. http://dx.doi.org/10.1152/ajpgi.00143.2013.

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Zymogen granule (ZG) formation in acinar cells involves zymogen cargo sorting from trans-Golgi into immature secretory granules (ISGs). ISG maturation progresses by removal of lysosomal membrane and select content proteins, which enter endosomal intermediates prior to their apical exocytosis. Constitutive and stimulated secretion through this mechanism is termed the constitutive-like and minor-regulated pathways, respectively. However, the molecular components that control membrane trafficking within these endosomal compartments are largely unknown. We show that tumor protein D52 is highly exp

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Zhu, Yulong, Changzheng Li, Shupei Tang, et al. "Deep-Learning-Driven Technique for Accurate Location of Fire Source in Aircraft Cargo Compartment." Fire 8, no. 8 (2025): 287. https://doi.org/10.3390/fire8080287.

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Accurate fire source location in an aircraft cargo compartment cannot be determined by common design practices. This study proposes an advanced fire location inversion framework based on a Convolutional Long-Short-Term Memory (ConvLSTM) network. A self-designed interpolation preprocessing module is introduced to realize the integration of spatial and temporal sensor data. The model was trained and validated using a comprehensive database generated from large-scale fire dynamics simulations. Hyperparameter optimization, including a learning rate of 0.001 and a 5 × 5 convolution kernel size, can

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Westrate, Laura M., Melissa J. Hoyer, Michael J. Nash, and Gia K. Voeltz. "Vesicular and uncoated Rab1-dependent cargo carriers facilitate ER to Golgi transport." Journal of Cell Science 133, no. 14 (2020): jcs239814. http://dx.doi.org/10.1242/jcs.239814.

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ABSTRACTSecretory cargo is recognized, concentrated and trafficked from endoplasmic reticulum (ER) exit sites (ERES) to the Golgi. Cargo export from the ER begins when a series of highly conserved COPII coat proteins accumulate at the ER and regulate the formation of cargo-loaded COPII vesicles. In animal cells, capturing live de novo cargo trafficking past this point is challenging; it has been difficult to discriminate whether cargo is trafficked to the Golgi in a COPII-coated vesicle. Here, we describe a recently developed live-cell cargo export system that can be synchronously released fro

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Ponomareva, Natalia, Sergey Brezgin, Ivan Karandashov, et al. "Swelling, Rupture and Endosomal Escape of Biological Nanoparticles Per Se and Those Fused with Liposomes in Acidic Environment." Pharmaceutics 16, no. 5 (2024): 667. http://dx.doi.org/10.3390/pharmaceutics16050667.

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Biological nanoparticles (NPs), such as extracellular vesicles (EVs), exosome-mimetic nanovesicles (EMNVs) and nanoghosts (NGs), are perspective non-viral delivery vehicles for all types of therapeutic cargo. Biological NPs are renowned for their exceptional biocompatibility and safety, alongside their ease of functionalization, but a significant challenge arises when attempting to load therapeutic payloads, such as nucleic acids (NAs). One effective strategy involves fusing biological NPs with liposomes loaded with NAs, resulting in hybrid carriers that offer the benefits of both biological N

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Kaur, Harsimran, Daniela Sparvoli, Hiroko Osakada, Masaaki Iwamoto, Tokuko Haraguchi, and Aaron P. Turkewitz. "An endosomal syntaxin and the AP-3 complex are required for formation and maturation of candidate lysosome-related secretory organelles (mucocysts) in Tetrahymena thermophila." Molecular Biology of the Cell 28, no. 11 (2017): 1551–64. http://dx.doi.org/10.1091/mbc.e17-01-0018.

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The ciliate Tetrahymena thermophila synthesizes large secretory vesicles called mucocysts. Mucocyst biosynthesis shares features with dense core granules (DCGs) in animal cells, including proteolytic processing of cargo proteins during maturation. However, other molecular features have suggested relatedness to lysosome-related organelles (LROs). LROs, which include diverse organelles in animals, are formed via convergence of secretory and endocytic trafficking. Here we analyzed Tetrahymena syntaxin 7-like 1 (Stx7l1p), a Qa-SNARE whose homologues in other lineages are linked with vacuoles/LROs.

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Mainou, Bernardo A., and Terence S. Dermody. "Transport to Late Endosomes Is Required for Efficient Reovirus Infection." Journal of Virology 86, no. 16 (2012): 8346–58. http://dx.doi.org/10.1128/jvi.00100-12.

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Rab GTPases play an essential role in vesicular transport by coordinating the movement of various types of cargo from one cellular compartment to another. Individual Rab GTPases are distributed to specific organelles and thus serve as markers for discrete types of endocytic vesicles. Mammalian reovirus binds to cell surface glycans and junctional adhesion molecule-A (JAM-A) and enters cells by receptor-mediated endocytosis in a process dependent on β1 integrin. Within organelles of the endocytic compartment, reovirus undergoes stepwise disassembly catalyzed by cathepsin proteases, which allows

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