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M., Nilofer Noorie, and Chenthamarai G. "Anti-fungal activity of Carica papaya leaf extract against candida albicans and its synergy with fluconazole: an in-vitro study." International Journal of Basic & Clinical Pharmacology 10, no. 1 (December 23, 2020): 101. http://dx.doi.org/10.18203/2319-2003.ijbcp20205547.
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Background: In this study objectives were to evaluate the antifungal activity in increasing concentrations of ethanolic extract and aqueous extract of Carica papaya against Candida albicans and to assess the synergistic activity of ethanolic extract of Caricia papaya with flucanazole as a potential antifungal.Methods: The aim of the study was to evaluate the antifungal activity in increasing concentrations, 500 µl/ml, 750 µl/ml and 1000 µl/ml of ethanolic extract and aqueous extract of caricia papaya against Candida albicans and the synergistic activity with Fluconazole was assessed by observing the zone of inhibition in agar disc diffusion assay and by observing the turbidity in minimum inhibitory concentration (MIC) assay.Results: It was observed that ethanolic extract of Carica papaya leaf showed significant antifungal activity in higher concentration of 1000µg/ml with zone diameter of 11.97±0.15 mm in disc diffusion assay and MIC of 350 µg/ml. The ethanolic extract of Carica papaya leaf with fluconazole showed synergistic activity with zone diameter of 13.6±0.45 mm in disc diffusion assay and MIC was 125µg/ml, whereas the standard drug Fluconazole’s zone of inhibiton was 12.83±0.9 in disc diffusion and MIC was 500 µg/ml.Conclusions: From this study, we can safely conclude that the Carica papaya leaf extract has a significant antifungal property and exhibit synergistic effect when used with fluconazole.
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Vachel, Jovi, and Wirawan ED Radianto. "PENGARUH KUALITAS PRODUK, HARGA PRODUK, DAN KEMASAN PRODUK TERHADAP KEPUTUSAN PEMBELIAN (STUDI KASUS PADA JUS BUAH DEPOT SALMON DI SURABAYA." PERFORMA 4, no. 5 (February 24, 2021): 700–707. http://dx.doi.org/10.37715/jp.v4i5.1689.
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This research is based on the failure of researchers' business namely Carico, Carico is a company engaged in the Food and Baverage industry, Carico is one of the original local brands of Indonesia, which sells authentic Carica fruit juice, Carica fruit can only grow in 2 places in the world. Carica fruit juice with a sweet and fresh taste has many health benefits, such as smooth digestion. However, as the sales process in Carico fluctuated, the researchers wanted to benchmark with similar competitors. Researchers use Salmon Depot Juice as a benchmarking in this study because the Salmon Depot Juice business is much better profit. Jus Depot Salmon was established in 2016 at Ciputra University in Surabaya. Prices offered by Salmon Depot juice range from IDR 10,000 - IDR 20,000. Salmon Depot Juice uses one employee and sells a variety of juice variants. In one day, it can sell 100 to 150 cups with a turnover of Rp 1,000,000 to Rp 2,000,000. Consumers who buy are Ciputra University students. The formulation of the problem in this study is whether the quality, price, and packaging of the product affect the purchasing decision of salmon depot fruit juice products in Surabaya. That is expected to be input for researchers in making improvements and adding insights about purchasing decisions, product quality, product prices and product packaging in running a food and beverage industry business. Researchers used quantitative methods with a population of consumers who bought Salmon Depot juice products in Surabaya with an infinite amount, using 385 people taken from the formula according to (Sugiyono, 2018; 142). The data collection method uses an offline questionnaire using a Likert scale and uses multiple linear regression analysis. The results of this study are the quality, price and product packaging significantly influence purchasing decisions.
Keywords: product quality, product prices, product packaging, purchasing decisions.
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Astuti, Tri Dyah, and Wahid Syamsul Hadi. "Potensi Ekstrak Daun Carica Pubescens Sebagai Alternatif Antidiare Bakteri Vibrio cholerae dan Shigella dysentriae." Jurnal Teknologi Laboratorium 7, no. 2 (December 31, 2018): 61–69. http://dx.doi.org/10.29238/teknolabjournal.v7i2.138.
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Diare akut merupakan salah satu penyebab utama morbiditas dan mortalitas. Masyarakat mulai memilih obat tradisional atau obat herbal sebagai pengobatan alternatif. Obat tradisional atau obat herbal dinilai lebih aman dan tidak memberikan efek samping seperti obat kimia. Tujuan dari penelitian ini adalah untuk mengetahui efek anti diare ekstrak daun Carica pubescens terhadap bakteri Vibrio cholerae dan Shigella dysentriae. Penelitian ini dilakukan dengan menguji aktivitas bakteri Vibrio cholerae dan Shigella dysentriae terhadap ekstrak daun Carica pubescens dengan metode sumuran yang hasilnya dapat dilihat dari terbentuknya zona hambat. Data yang diperoleh diolah menggunakan statistik uji Two Way ANOVA. Hasil penelitian menunjukkan ekstrak daun Caricap pubescens konsentrasi 100% mempunyai efek terapi terbaik karena mempunyai daya hambat terbesar terhadap bakteri Vibrio cholerae maupun Shigella dysentriae.
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Nicotra, Giovanna, Silvia Vicentini, and Angelica Mazzolari. "Ficus carica." Nutrafoods 9, no. 3 (July 2010): 27–30. http://dx.doi.org/10.1007/bf03223339.
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Mahmudati, Rina. "KLASIFIKASI TINGKAT KEMATANGAN BUAH CARICA MENGGUNAKAN FUZZY LOGIC." Device 11, no. 2 (November 30, 2021): 1–4. http://dx.doi.org/10.32699/device.v11i2.1958.
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Buah carica adalah salah satu ciri khas kota Wonosobo, dimana banyak dijumpai di dataran tinggi Dieng. Selain teksturmya yang kenyal, mempunyai aroma yang segar juga memiliki kandungan serat yang tinggi untuk membantu melancarkan proses pencernaan serta mengandung Vitamin C dan E sehingga baik untuk kesehatan kulit. Carica memiliki rasa yang manis asam dan bagian kulit mengandung banyak getah sehingga kurang enak jika dikonsumsi secara langsung. Masyarakat setempat biasa mengolah buah carica menjadi keripik oven, manisan, sirup, dodol, selai dan menjadikannya sebagai usaha baik usaha rumahan mandiri maupun usaha kelompok yang tergabung dalam UKM. Aneka olahan tersebut berbahan baku buah carica, namun dengan tingkat kematangan yang berbeda. Masyarakat pengolah carica seharusnya memiliki kemampuan dalam membedakan kematangan buah carica, agar dapat menghasilkan produk makanan dengan rasa yang lezat. Namun, sebagian besar pengolah carica masih banyak yang belum bisa mengetahui tingkat kematangan buah dengan tepat, mereka hanya melihat kematangan dari warna buah dan aroma yang muncul dari buah carica. Penelitian ini bertujuan untuk merancang suatu program untuk mengetahui tingkat kematangan buah carica dengan menggunakan logika fuzzy. Uji coba program telah dilakukan dan mencapai hasil bahwa dengan menggunakan metode logika fuzzy dan program sederhana dengan bahasa pemrograman python dapat digunakan untuk mengklasifikasikan tingkat kematangan buah carica
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Qin, Fengping, Yeyun Zhao, Gang Yao, and Guoquan Wang. "Three new species of eriophyoid mites (Acari: Eriophyoidea) from South Laos." Systematic and Applied Acarology 24, no. 7 (July 5, 2019): 1124–37. http://dx.doi.org/10.11158/saa.24.7.2.
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Three new species were described and illustrated from South Laos in this paper, two of them, Phetehaburus caricae sp. nov. infesting Carica papaya L. (Caricaceae) and Phyllocoptruta tabernaemontana sp. nov. infesting Tabernaemontana divaricata L. (Apocynaceae) belong to subfamily Phyllocoptinae (Eriophyidae) and another species, Diptilomiopus careyus sp. nov. infesting Careya arborea Roxb. (Lecythidaceae) belongs to Diptilomiopinae (Diptilomiopidae). All the new species described herein are vagrants on the host plant.
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Asmoro Bangun, Putro Panji. "Analisis kadar total flavonoid pada daun dan biji pepaya (carica papaya l.) Menggunakan metode spektrofotometer Uv-Vis." Jurnal Ilmiah Farmasi Attamru 2, no. 1 (November 19, 2021): 1–5. http://dx.doi.org/10.31102/attamru.v2i1.1263.
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Analisis kadar flavonoid total ekstrak daun dan biji pepaya (Carica papaya L.) dengan metode spektrofotometri UV-Vis. Tujuan penelitian ini dilakukan karena pemanfaatan daun dan biji pepaya pepaya (Carica papaya L.) masih kurang, serta untuk mengetahui kadar flavonoid total yang terkandung dalam ekstrak daun dan biji pepaya (Carica papaya L.). Ekstraksi kandungan kimia dari daun dan biji pepaya (Carica papaya L.) dilakukan dengan metode maserasi menggunakan etanol 96%. Untuk menentukan kadar senyawa flavonoid pada ekstrak sampel, maka dilakukan analisis senyawa menggunakan spektrofotometri UV-Vis. Dari hasil penelitian diperoleh analisis kualitatif senyawa flavonoid masing-masing daun dan biji pepaya (Carica papaya L.) dari ekstrak etanol 96% terjadi perubahan menjadi warna merah bata yang menunjukkan positif mengandung flavonoid. Sedangkan Pengukuran absorbansi dilakukan menggunakan spektrofotometri UV-Vis dengan panjang gelombang 510 nm. 5 ppm nilai absorbansinya (0,214), 10 ppm nilai absorbansinya
(0,3799), 15 ppm nilai absorbansinya (0,5126), dan 20 ppm nilai absorbansinya (0,7033). Serta pengukuran kadar flavonoid total daun pepaya (Carica papaya L.) dari ekstrak etanol 96% sebesar 17,4633 mg QE/g atau 1,7463 % dan kadar flavonoid total biji pepaya (Carica papaya L.) dari ekstrak etanol 96% sebesar 15,8181 mg QE/g atau 1,5818 %. Hasil tersebut menunjukkan bahwa ekstrak daun pepaya (Carica papaya L.) memiliki kadar flavonoid lebih tinggi dibandingkan dengan ekstrak biji pepaya (Carica papaya L.).
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Singh, Mahipal, Pushpa Yadav, and Anand K. Yadav. "Cloning and Sequence Analysis of 5S Ribosomal RNA Gene(s) and Associated Intergenic Spacer Regions in Carica Species." International Journal of Biology 13, no. 1 (March 30, 2021): 1. http://dx.doi.org/10.5539/ijb.v13n1p1.
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The 5S ribosomal RNA gene(s) and their associated intergenic spacer regions were amplified from Carica papaya and Carica quercifolia by polymerase chain reaction. Both Carica species exhibited differently sized amplification products. Sequence analysis of these PCR products revealed that the 5S rRNA genes are arranged as tandem repeats in these regions. Sequence data revealed that the 5S rRNA gene from Carica quercifolia was 119 bp in length. Sequence variation was observed in various 5S rRNA gene copies cloned from Carica quercifolia. Only truncated 5S rRNA gene but with its full spacer region was recovered from Carica papaya. Interestingly, intergenic spacer sequence cloned from Carica papaya contained two specific domains, a 30bp “CT” rich domain exhibiting 95-100% homology to several human chromosomes and a domain matching with mitrocomin precursor, a photo-protein from Mitrocoma cellularia. The role of 5S rRNA gene and their spacer regions in discerning the germplasm and in adaptation of the species is discussed.
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Meiyana, Ulfi, Rizki Ardiawan, Fiqoh Khoeriyah, and Ahmad Khoiri. "Analisis Usaha Kreatif Potensi Lokal Wonosobo Melalui Produk Coklat Sari Carica Dieng." Jurnal Pengabdian Dharma Laksana 4, no. 1 (September 20, 2021): 67. http://dx.doi.org/10.32493/j.pdl.v4i1.13184.
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Pentingnya menggali usaha kreatif melalui COKSACAR (Coklat Sari Carica) yang dijadikan sebagai alternative solusi untuk mengatasi kejenuhan buah carica yang hanya dibuat sebagai makanan ringan seperti manisan dan kripik saja. Kegiatan Kewirausahaan dilakukan untuk: 1) Melatih kreativitas dan keterampilan dalam menciptakan inovasi baru yang berbahan baku Potensi lokal buah carica melalui kajian edupreneurscience (Sains dan ekonomi); 2) Menyajikan buah carica yang berbeda dari lainnya dengan tambahan variasi rasa, sehingga dapat menghilangkan kejenuhan cemilan buah yang biasanya; dan 3)Membuka peluang usaha baru untuk memperoleh laba yang nantinya bisa membuka lapangan pekerjaan. Metode penelitian melalui tahap persiapan produksi pada alat dan bahan; proses produksi dengan mengkaji edupreneurscience; dan pemasaran melalui analisis SWOT dan Mix Marketing 4P. Berdasarkan kegiatan kewirausahaan menunjukan bahwa: 1) Produk COKSACAR memanfaatkan potensi lokal Wonosobo dalam meningkatkan nilai jual buah carica serta dapat dikaji melalui viskositas sari carica dan potensi pengembangan usaha; 2) Terciptanya kegiatan kewirausahaan Produksi COKSACAR beraneka rasa meliputi rasa original, mocca, Green tea dan vanilla dengan rasa sari carica sehingga dapat menghilangkan kejenuhan dalam mengkonsumsi buah carica pada umumnya; dan 3)Menghasilkan pendapatan, peluang usaha baru serta mengurangi jumlah pengangguran karena pengembangan usaha yang berkelanjutan.
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Kaur, Ramandeep, and Kalyan Sen. "Antiulcer activity of hydroalcoholic extract of unripe fruit of carica papaya in experimental rats." International Journal of Basic & Clinical Pharmacology 6, no. 2 (January 28, 2017): 432. http://dx.doi.org/10.18203/2319-2003.ijbcp20170344.
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Background: Carica papaya has previously reported antioxidant, analgesic and anti-inflammatory, antibacterial and anti-histaminic activity. Peptic ulcer disease involves inflammation and oxidative stress, so hydroalcoholic extract of Carica papaya fruits may have strong potential for an antiulcer agent. Aim and objectives of the study were in this study pharmacological evaluation of antiulcer effect of hydroalcoholic extract of Carica papaya fruits was performed by pyloric ligation induced gastric ulcers.Methods: Preliminary phytochemical investigation, estimation of phenolic and flavonoid content, In vitro antioxidant activities, antiulcer activity to find out the efficacy of hydroalcoholic extract of Carica papaya fruits.Results: Treatment with 500 mg/kg of hydroalcoholic extract of Carica papaya fruits efficacious in reducing ulcer index in pyloric ligation induced gastric ulcer model. Hydroalcoholic extract Carica papaya of showed a dose dependent decrease in ulcer and reduces ulcer index which was supported by morphological and histological studies.Conclusions: Thus it can be concluded that hydroalcoholic extract of Carica papaya fruits have antiulcer activity, which can be attributed to its antioxidant mechanism of action.
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Olafsdottir, E. "Cyanogenesis in glucosinolate-producing plants: Carica papaya and Carica quercifolia." Phytochemistry 60, no. 3 (June 2002): 269–73. http://dx.doi.org/10.1016/s0031-9422(02)00106-1.
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Herliani, Diar Rizkiqa, Djoko Sumarjono, and Bambang Mulyatno Setiawan. "ANALISIS PENDAPATAN USAHATANI MONOKULTUR KENTANG DAN TUMPANGSARI KENTANG-CARICA DESA SEMBUNGAN KECAMATAN KEJAJAR KABUPATEN WONOSOBO." SOCA: Jurnal Sosial, Ekonomi Pertanian 13, no. 3 (December 31, 2019): 291. http://dx.doi.org/10.24843/soca.2019.v13.i03.p01.
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Cropping petterns of farmers in Sembungan Village are monoculture and intercropping. This study examines more profitable and can evaluate cropping patterns using intercropping and monoculture. Farmers in Sembungan Village have not paid attention to operational costs, net income and sustainability feasibility as measured by the R/C ratio. This reasearch aims to analyze net income, profitability and R/C ratio of the planting system potato monoculture and the planting system potato-carica intercropping. The reasearch method used survey method location was decided by purposive method. The number of respondents decided by nonprobability sampling that is sampling quota. The samples determined by 30 potato farmers and 30 potato-carica farmers. Respondent decided by snowball sampling. The analyze used two-sample assuming equal variences used microsoft excel. The results of reasearch that the net income of potato-carica intercropping significantly higher than the net income of potato monoculture. Net income of potato-carica intercropping is Rp 17,386,588.2 and Net income of potato monoculture is Rp 7,537,404.3. Profitability of potato-carica intercropping significantly higher than the profitability of potato monoculture. Profitability of potato-carica intercropping is 60.39% and profitability of potato monoculture is 44.07%. R/C ratio of potato-carica intercropping higher than R/C ratio of potato monoculture. R/C ratio of potato-carica intercropping is 1.60 and R/C ratio of potato monoculture is 1.44.
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Dianti, Siti, and Heny Kusumayanti. "Formulation of Antibacterial Liquid Soap Based on Virgin Coconut Oil with Various Concentrations of Carica Concentrate and Potassium Hydroxide Volume." Journal of Vocational Studies on Applied Research 4, no. 1 (July 12, 2022): 13–17. http://dx.doi.org/10.14710/jvsar.v4i1.14140.
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Carica is one of the main commodities in Dieng, Central Java. It contains vitamin A, vitamin C, and antibacterial substances such as flavonoid, polifenol, and tannin. Due to its content, carica can be used as an additive for soap products. Soap is one of the cosmetic products, produced from the saponification reaction between alkali and fatty acids. Carica liquid soap was carried out by reacting KOH with virgin coconut oil that contains fatty acids, then adding carica fruit juice and other ingredients. The product of liquid soap will be analyzed including pH, density, free fatty acids content, organoleptic test, and antibacterial activity. The research method used is a factorial design. Research has shown that the carica liquid soap were in accordance with SNI 06-4075-1996 and SNI 06-3532-1994. The best quality of carica liquid soap obtained at pH 11, density 1,0266, and free fatty acid content of 0,082%. Antibacterial activity was carried out using the paper disk method, showing that the antibacterial activity of the soap has a weak performances with an inhibition zone of 1,25 mm. The organoleptic test showed that panelist’s preference for carica liquid soap was low.
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Dianti, Siti, and Heny Kusumayanti. "Formulation of Antibacterial Liquid Soap Based on Virgin Coconut Oil with Various Concentrations of Carica Concentrate and Potassium Hydroxide Volume." Journal of Vocational Studies on Applied Research 3, no. 3 (July 12, 2022): 68–72. http://dx.doi.org/10.14710/jvsar.v3i3.14140.
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Carica is one of the main commodities in Dieng, Central Java. It contains vitamin A, vitamin C, and antibacterial substances such as flavonoid, polifenol, and tannin. Due to its content, carica can be used as an additive for soap products. Soap is one of the cosmetic products, produced from the saponification reaction between alkali and fatty acids. Carica liquid soap was carried out by reacting KOH with virgin coconut oil that contains fatty acids, then adding carica fruit juice and other ingredients. The product of liquid soap will be analyzed including pH, density, free fatty acids content, organoleptic test, and antibacterial activity. The research method used is a factorial design. Research has shown that the carica liquid soap were in accordance with SNI 06-4075-1996 and SNI 06-3532-1994. The best quality of carica liquid soap obtained at pH 11, density 1,0266, and free fatty acid content of 0,082%. Antibacterial activity was carried out using the paper disk method, showing that the antibacterial activity of the soap has a weak performances with an inhibition zone of 1,25 mm. The organoleptic test showed that panelist’s preference for carica liquid soap was low.
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Mela, Ervina, Vincentius Prihananto, and Arista Savira Raharjaningtyas. "ATRIBUT PRIORITAS UNTUK PERBAIKAN MUTU PRODUK KOKTAIL CARICA CV XYZ BERDASARKAN TINGKAT KEPUASAN DAN KEPENTINGAN KONSUMEN." Agrin 24, no. 2 (March 29, 2021): 137. http://dx.doi.org/10.20884/1.agrin.2020.24.2.546.
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CV XYZ merupakan salah satu UMKM di Kabupaten Wonosobo yang mengolah buah carica menjadi koktail. Semakin ketatnya persaingan produk sejenis, perusahaan berusaha untuk terus meningkatkan mutu produknya dengan cara memperbaiki atribut produk yang masih lemah. Tujuan dari penelitian ini adalah untuk mengidentifikasi atribut prioritas untuk perbaikan mutu koktail carica CV XYZ berdasarkan kepuasan dan kepentingan konsumen. Atribut mutu produk dikelompokkan berdasarkan dua parameter yaitu buah carica, dan sirup koktail. Penelitian dilakukan dengan menyebarkan kuesioner kepada 100 responden secara purposive sampling. Data dianalisis menggunakan Importance Performance Analysis. Atribut prioritas untuk perbaikan mutu produk adalah banyaknya sirup dan aftertaste. Hasil penelitian menunjukan bahwa perbaikan dalam peningkatan mutu koktail carica berupa penambahan sirup dan pengujian sensoris aftertaste sirup dengan melibatkan panelis ahli.Kata kunci: koktail carica, tingkat kepuasan, tingkat kepentingan
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Wulansari, Endang Dwi, Dewi Lestari, and Mujahidah Asma Khoirunissa. "KANDUNGAN TERPENOID DALAM DAUN ARA (Ficus carica L.) SEBAGAI AGEN ANTIBAKTERI TERHADAP BAKTERI Methicillin-Resistant Staphylococcus aureus." PHARMACON 9, no. 2 (May 28, 2020): 219. http://dx.doi.org/10.35799/pha.9.2020.29274.
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ABSTRACT Fig leaves (Ficus carica L.) are known to the public with many health benefits. The content of efficacious compounds in fig leaves such as terpenoids has potential as an antibacterial and needs to be known. This study aims to determine the antibacterial activity of terpenoid content in extracts and fractions of fig leaves (Ficus carica L.) on the growth of Methicillin-Resistant Staphylococcus aureus (MRSA) bacteria by contact bioautography. Extraction was carried out by stratified soxhletation with n-hexane and ethyl acetate. Separation was carried out by coloum vacuum liquid chromatography (VLC) method. The wells diffusion method is used as the antibacterial activity test, while the TLC contact bioautography test is carried out to determine the antibacterial activity of the terpenoid content in the extracts and fractions. Extracts of n-hexane, ethyl acetate, and ethanol of fig leaf (Ficus carica L.) have antibacterial activity against MRSA with a diameter of inhibitory zone 0.111 ± 0.003; 0.328 ± 0.026, 1.044 ± 0.115 cm, and show significant differences. Extracts of n-hexane, ethyl acetate, and ethanol of fig leaf (Ficus carica L.) contain terpenoids. The fraction of ethyl acetate and ethanol extracts of fig leaves (Ficus carica L.) contains terpenoid compounds which can provide antibacterial activity against MRSA by TLC contact bioautography. Keywords: fig leaves, Ficus carica L., antibacterial, Methicillin-Resistant S. aureus. ABSTRAK Daun ara (Ficus carica L.) dikenal masyarakat dengan banyak manfaat dalam bidang kesehatan. Kandungan senyawa berkhasiat dalam daun ara seperti terpenoid berpotensi sebagai antibakteri dan perlu diketahui. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri kandungan terpenoid dalam ekstrak maupun fraksi daun ara (Ficus carica L.) terhadap pertumbuhan bakteri Methicillin-Resistant Staphylococcus aureus (MRSA) secara KLT bioautografi kontak. Ekstraksi dilakukan dengan cara soxhletasi bertingkat dengan pelarut n-heksana dan etil asetat. Pemisahan dilakukan dengan metode kromatografi kolom vakum cair (KVC). Uji aktivitas antibakteri menggunakan metode difusi sumuran, sedangkan uji bioautografi kontak dilakukan untuk mengetahui aktivitas antibakteri kandungan terpenoid dalam ekstrak dan fraksi. Ekstrak n-heksana, etil asetat, dan etanol daun ara (Ficus carica L.) mempunyai aktivitas antibakteri terhadap MRSA dengan diameter zona hambat berturut-turut 0,111±0,003; 0,328±0,026, 1,044±0,115 cm, dan menunjukkan perbedaan signifikan. Ekstrak n-heksana, etil asetat, dan etanol daun ara (Ficus carica L.) mengandung terpenoid. Fraksi dari ekstrak etil asetat dan etanol daun ara (Ficus carica L.) mengandung senyawa terpenoid yang dapat memberikan aktivitas antibakteri terhadap MRSA secara KLT bioautografi kontak. Kata kunci : daun ara, Ficus carica L., antibakteri, Methicillin-Resistant S. aureus
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Yunita, Mulya, and Rahmawati Rahmawati. "PENGARUH LAMA PENGERINGAN TERHADAP MUTU MANISAN KERING BUAH CARICA (Carica candamarcensis)." JURNAL KONVERSI 4, no. 2 (April 1, 2015): 17. http://dx.doi.org/10.24853/konversi.4.2.17-28.
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Carica merupakan buah khas daerah Dieng yang memiliki rasa asam, pahit dan air tinggi, sehingga buah jarang dikonsumsi segar dan cepat rusak. Salah satu upaya untuk meningkatkan kegunaan buah, dengan mengurangi rasa asam dan kandungan airnya maka dibuat menjadi manisan kering. Manisan kering merupakan makanan ringan yang awet, dibuat dengan menambahkan gula dan mengeringkannya. Penelitian bertujuan mempelajari waktu pengeringan untuk memperoleh manisan kering buah carica berkualitas baik berdasarkan uji fisik (kekerasan dan rendemen), kimia (serat kasar, kadar air, kadar abu, protein, lemak, karbohidrat by different, Aw, total padatan terlarut, total gula dan total asam) serta uji organoleptik (uji mutu hedonik untuk warna, bau, tekstur, dan rasa; serta uji rangking berdasarkan tekstur). Data dianalisa dengan uji Anova dan uji lanjut Duncan. Waktu pengeringan yang digunakan adalah 9, 9.5, 10, 10.5 dan 11 jam. Hasil menunjukkan bahwa waktu pengeringan 10 jam menghasilkan produk terbaik. Karakteristik produk ini adalah mempunyai kekerasan 5593.28gf, rendemen 26.14%, serat kasar 1.08%, kadar air 20.05%, kadar abu 0.88%, kadar protein 1.39%, lemak 0.012%, karbohidrat by different 77.68%, aw 0.62%, total padatan terlarut 39.39% total dissolve solid, total gula 45.86%, total asam 0.61%, berwarna kekuningan, aroma buah kuat, tekstur yang kenyal dan berasa manis.
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Diana, Nur, and Lilis Majidah. "IDENTIFIKASI JAMUR RHIZOPUS SP PADA BUAH PEPAYA JINGGA (Carica papaya L.)." Jurnal Insan Cendekia 6, no. 1 (March 7, 2019): 44–48. http://dx.doi.org/10.35874/jic.v6i1.533.
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Pendahuluan Buah Pepaya Jingga (Carica papaya L.) merupakan salah satu varietas lokal yang paling banyak disukai oleh masyarakat Indonesia, karena memiliki kelezatan rasa dan penampilannya yang menarik. Buah pepaya Jingga (Carica papaya L.) tumbuh baik di dataran tinggi maupun di dataran rendah. Masalah sekarang tidak semua pepaya jingga dalam bentuk segar yang harus dikonsumsi oleh masyarakat. Pemeriksaan ini bertujuan untuk mengetahui apakah terdapat jamur Rhizopus sp pada pepaya jingga (Carica papaya L.) Pada penelitian ini menggunakan Metode Deskriptif. Sampel dilakukan dengan cara menanamkan sebagian bahan pemeriksaan atau buah pepaya jingga (Carica papaya L.) pada media Sabaroud Dextrose Agar (SDA) dan diinkubasi selama 3-7 hari. Sampel yang diambil buah yang setengah matang kemudian diinkubasi pada suhu kamar selama 4 hari, sampel diambil sebanyak 4 buah dengan tehnik purporsive sampling. Instrumen penelitian ini menggunakan mikroskop. Variabel dalam penelitian ini adalah jamur Rhizopus sp pada buah pepaya jingga (Carica papaya L.). Teh debnik pengolahan data meliputi coding dan tabulating dengan analisa data penelitian ini menggunakan rumus untuk mengklarifikasikan karakteristik data. Berdasarkan Hasil penelitian terhadap 4 sampel pepaya jingga (Carica papaya L.) adanya sampel yang ditumbuhi oleh jamur Rhizopus sp (50%) dan Aspergillus sp (50%). Kesimpulan jamur yang mengkontaminasi atau didominasi buah pepaya jingga (Carica papaya L.) menunjukkan persentase setengah oleh jamur Rhizopus sp. Berdasarkan hasil penelitian yang dilakukan, Saran bagi konsumen hendaknya memilih dan membedakan buah yang baik untuk dikonsumsi.
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Dozie-Nwakile, Ogechukwu Calista, Calista Dozie Nwakile, Ngozi Felicia Onyemelukwe, Seto Aladenika, Adaobi Chisom Uchenna, and Emmanuel Chibuzor Ugwu. "Antibacterial and Antifungal Effects of Carica papaya and Cucurbita specie Seed Extracts on Escherichia coli and Aspergillus flavus." Journal of Drug Delivery and Therapeutics 10, no. 3-s (June 25, 2020): 189–95. http://dx.doi.org/10.22270/jddt.v10i3-s.4133.
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Objective: In this work, we studied the antifungal and anti-bacterial properties of seeds of Carica papaya and Curcubita specie using selected bacteria and fungi.
Methods: Modified cold extraction method with ethanol and n-hexane was conducted. Antimicrobial properties of the extracts were done using agar block dilution for fungi and agar diffusion method for the bacteria. Measurement of the mean growth rate (MGR) for the fungi isolate and the inhibition zone diameter (IZD) for the bacteria were used as parameters.
Results: Significant antifungal property was observed in ethanolic extract of Carica papaya at a concentration of 6% at four days of its exposure, while n-hexane extract of Carica papaya and ethanolic extract of Curcubita specie show fungistatic action. Ethanolic extract of Carica papaya at 6% concentration showed more antifungal property than the control drug. Antibacterial action for all the test extracts was poor, with the control drug showing more significant action than the extracts. There was a statistical significance difference between the ethanolic extract of Carica papaya and Curcubita specie (p< 0.05).
Conclusion: This is an indication that ethanolic extract of Carica papaya can be used in the treatment of some of the fungal infection caused by Aspergillus flavus likewise n-hexane extracts.
Keywords: Antifungal, Anti-bacterial, Carica papaya, Curcubita specie, ethanolic extract, n-hexane extract.
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Sugito, Sugito, and Edy Suwandi. "Efektifitas Ekstrak Ethanol Daun Pepaya (Carica Papaya L) terhadap Pertumbuhan Bakteri Escherichia Coli dengan Metode Difusi." Jurnal Laboratorium Khatulistiwa 1, no. 1 (November 30, 2017): 21. http://dx.doi.org/10.30602/jlk.v1i1.91.
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Abstract: Papaya plant (Carica papaya L) is also called medicinal plant which is used in traditional medicine. Part of papaya plants (Carica papaya L) which often utilized are papaya leaf (Carica papaya L) because its content of substances or active ingredients is antibacterial, cancer prevention, increase appetite, and treat some diseases caused by bacteria. The aim of this research was to determined the extracted ethanol of papaya leaf (Carica Papaya L) with the growth of Escherichia coli bacteria by the diffusion method. Research design which used in this study was experimental research, with the method of sampling purposive sampling, then the results analyzed with Friedman Test. A result of research from 5 replications test of extract concentration of papaya leaf by diffusion method obtained that the minimum average concentration was 10,00 and maximize was 14,20. While the minimum inhibitory zone diameter was 10 mm with the concentration of 10% and the maximum was 15 mm with the concentration of 20%. A result of Friedman test, it was found that (p = 0,00 <0,05) so it can be declared that there was a difference of papaya leaf extract (Carica Papaya L) effect on Escherichia coli bacteria growth by the diffusion method.Abstrak: Tanaman pepaya (Carica papaya L) disebut juga tanaman obat yang bermanfaat untuk pengobatan tradisional. Bagian yang sering dimanfaatkan pada tanaman pepaya (Carica papaya L) adalah daun pepaya (Carica papaya L) karena mengandung zat atau bahan aktif yang bersifat sebagai antibakteri, pencegahan kanker, menambah nafsu makan dan mengobati beberapa penyakit yang disebabkan oleb bakteri. Tujuan penelitian adalah untuk mengetahui ekstrak ethanol daun pepaya (Carica Papaya L) terhadap pertumbuhan bakteri Escherichia coli dengan metode difusi. Desain penelitian yang digunakan dalam penelitian ini adalah penelitian eksperimental dengan metode pengambilan sampel purposive sampling, selanjutnya hasil dianalisis menggunakan uji Friedman. Hasil penelitian dari 5 penggulangan uji konsentrasi ekstrak daun pepaya dengan metode difusi dapat diketahui rata-rata konsentrasi minimum 10,00 dan maksimun 14,20. Sedangkan diameter zona hambat minimum adalah 10 mm dengan konsentrasi 10% dan maksimun adalah 15 mm dengan konsentrasi 20%. Hasil Friedmen test diperoleh nilai (p = 0,00 < 0,05) sehingga dapat dinyatakan bahwa terdapat perbedaan efektiftas ekstrak daun pepaya (Carica Papaya L) terhadap pertumbuhan bakteri Escherichia coli dengan metode difusi.
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Fajriyah, Shinta Nur, Yuliana Eka Lestari, Nadiatul Istiqamah Suaka, and Endang Darmawan. "Narrative Review: Nano Kapsul Ekstrak Biji papaya (Carica Papaya L.) sebagai Antifertilitas." Jurnal Surya Medika 6, no. 2 (February 15, 2021): 10–24. http://dx.doi.org/10.33084/jsm.v6i2.1688.
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Papaya (Carica Papaya L.) is a plant commonly found in Indonesia. Interestingly, its seeds traditionally used as antifertility. All parts of the Carica Papaya tree can be used for human needs from the fruit, leaves, seeds, sap, and stems. Carica Papaya seed extract contains secondary metabolite compounds in class Triterpenoids, flavonoids, alkaloids, saponins, and tannins which have functioned as antifertility. Nanocapsule is an innovation of nanoparticle dosage form with small particle size, that can accelerate the drug to the target. This Narrative Review purposed to determine the usefulness of the nanocapsules of Carica Papaya seed extract as antifertility. This research is a Narrative Review. A total of 36 articles that met the inclusion and exclusion criteria were analyzed descriptively, which include the efficacy of Carica Papaya, nanocapsules, and antifertility. The articles used include articles published in national journals and international journals. The result of the Narrative Review is presented in descriptive form. The results of the research show that Carica Papaya can be used traditionally to treat skin diseases, diarrheal disease, overcoming digestive disorders, and by research can be used as antifertility, The size of the nanoparticles obtained in the study ranged from 76.47 nm to 693.8 nm, and Carica Papaya seed extract is used as an antifertility by reducing sperm quantity, semen pH, spermatogenesis process, interfering the action of pituitary gonads, by preclinical reducing the number of ovum quality and the number of de Graff Follicles in female mice. Overall, it can be concluded that Carica Papaya nanocapsules in particle sizes between 76.46 nm to 693.8 nm can be used as antifertility that preclinically can affect the reproduction of female and male mice.
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Akintunde, Adeyinka Oye, Pokpah Kolu, Ibukunoluwa Adenike Akintunde, Samuel Adegoke Adewole, Olufunso Emmanuel Akinboye, Osagie John Afodu, Lois Chidinma Ndubuisi-Ogbonna, and Bolatito Adenike Shobo. "Evaluation of the Nutritive Values of Carica Papaya Fruit peels as A Potential Ingredient in Livestock Nutrition." ANIMAL PRODUCTION 24, no. 2 (July 29, 2022): 104–13. http://dx.doi.org/10.20884/1.jap.2022.24.2.129.
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The nutritive values of the peels of ripe and unripe fruits of Carica papaya were assessed for their potential in livestock production. Proximate and phytochemical analyses, as well as vitamins and mineral contents of the ingredients, were determined. Data were subjected to a t-test for statistical analysis. The crude protein (CP) of ripe and unripe Carica papaya peels were 3.50% and 10.30%. The ripe Carica papaya peels had 26.20%, 3.05%, 15.03%, 3.71%, 52.22%, 2.44%, and 1,060.09Kcal/Kg of crude fiber, crude fat, ash content, moisture, carbohydrate, fatty acid, and energy respectively while the unripe Carica papaya peels contained 27.10%, 22.30%, 13.30%, 4.15%, 27.00%, 17.84% and 1,459.20Kcal/Kg of crude fiber, crude fat, ash content, carbohydrate, fatty acid, and energy respectively. The ripe Carica papaya peels had significantly higher (p<0.05) values for calcium (0.39%), potassium (0.40%) and iron (570mg/Kg). The ripe Carica papaya peels had significantly higher (p<0.05) values of saponin (9.69mg/100g) while the unripe peels had significantly higher values (p<0.05) for alkaloid (6.44mg/100g), hydrogen cyanide (0.57mg/100g) and tannin (86.90mg/100g. Ripe Carica papaya peels having significantly higher (p<0.05) values for vitamin B1 (1.67mg/100g) and vitamin B6 (1.80mg/100g) while the unripe Carica papaya peels had significantly higher (p<0.05) values for vitamin A (3360IU/Kg), vitamins B2 (0.45mg/100g), B3 (3.25mg/100g), B12 (0.92mg/100g) and C (9.78mg/100g). It is concluded that these products offer a good source of basic vitamins and minerals and hold potential for therapeutic use in livestock nutrition. Therefore, the inclusion of these ingredients should be encouraged in livestock production, especially in the industry of monogastric animals.
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Karsidin, Bambang, Subagja ., and Revaldi Alfarizi Alfarizi. "Perbandingan Kadar Fenolik Total Antara Seduhan Daun Tin ( Ficuc crica L.) dan Teh Kombucha Daun Tin (Ficuc carica L.)." PRAEPARANDI : Jurnal Farmasi dan Sains 6, no. 1 (August 1, 2022): 20. http://dx.doi.org/10.58365/ojs.v6i1.180.
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Telah dilakukan penelitian tentang Perbandingan Kadar Fenolik Total Antara Seduhan Daun Tin (Ficus carica L.) Dan Teh Kombucha Daun Tin (Ficus carica L.). Penelitian ini bertujuan untuk mengetahui perbandingan kadar fenolik total antara seduhan daun tin (Ficus carica L.) dan teh kombucha daun tin (Ficus carica L.).
Tanaman tin (Ficus carica L.) merupakan tanaman yang berasal dari Asia Barat dan merupakan spesies dari kawasan Mediterania. Tanaman tin merupakan salah satu tanaman yang berpotensi sebagai antioksidan karena mengandung metabolit sekunder di seluruh bagian tanamannya seperti pada bagian daun. Daun tin (Ficus carica L.) mengandung senyawa fenolik dan senyawa metabolit sekunder lainnya seperti flavonoid, tanin, dan saponin. Kadar senyawa fenolik dapat dianalisa menggunakan spektrofotometri UV-Visible. Penentuan kadar fenolik total menggunakan metode Folin-Ciocalteu dengan standar asam galat dan dinyatakan dalam mg ekivalen asam galat (GAE) per gram simplisia.
Hasil analisis pada penelitian ini menunjukkan bahwa seduhan daun tin memiliki kadar fenolik total sebesar 126,3 mg GAE/g, dan kadar fenolik total teh kombucha daun tin sebesar 227,7 mg GAE/g.
Maka kesimpulan yang diperoleh bahwa perbandingan kadar fenolik total pada seduhan daun tin berbanding teh kombucha daun tin adalah 0,5 : 1.
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Kuswardahni, Nita, Ebban Bagus Kuntadi, and Titin Agustina. "Pengembangan Hasil Inovasi Teknologi Mie Instan ”Carika Pepaya Noodle” sebagai Penguat Diversifikasi Pangan Non Beras." CAKRAWALA 12, no. 2 (January 8, 2019): 178–95. http://dx.doi.org/10.32781/cakrawala.v12i2.273.
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Penelitian ini bertujuan untuk; pertama, mengenalkan kepada masyarakat terkait pemanfaatan pepaya menjadi produk mie instan sebagai upaya penguatan diversifikasi pangan non beras; kedua untuk melihat daya terima masyarakat terhadap produk mie instan carica papaya; ketiga untuk mengidentifikasi faktor pendorong dan faktor penghambat pemanfaatan mie carica papaya dalam penguatan diversifikasi pangan non beras. Lokasi penelitian ini ditentukan secara sengaja yaitu di Kabupaten Lamongan, Lumajang dan Jember. Metode analisis dalam penelitian ini menggunakan analisis statistik deskriptif, uji sensori (rasa, aroma, tekstur dan warna) daya terima masyarakat terhadap produk carica papaya. Hasil penelitian menunjukkan bahwa tingkat kehadiran peserta kegiatan sosialisasi dan praktek pembuatan Mie Carica Pepaya adalah 100%, seluruh peserta menyatakan puas terhadap pelaksanaan kegiatan. Hasil uji organoleptik terhadap “Mie Instan Carica Papaya” menunjukkan bahwa sebesar 84,67 % responden menyukai tekstur, 78,54% responden menyatakan suka dengan warna, 85,89% responden menyatakan suka terhadap rasa, 66,88% responden kurang menyukai aroma.
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Shanmugam, Kirubanandan, Tharunya P, Subha V, Sandhaya S, and Renganathan S. "GREEN SYNTHESIS OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE FROM FICUS CARICA FRUIT EXTRACT, CHARACTERIZATION STUDIES AND ITS APPLICATION ON DYE DEGRADATION STUDIES." Asian Journal of Pharmaceutical and Clinical Research 10, no. 3 (March 1, 2017): 125. http://dx.doi.org/10.22159/ajpcr.2017.v10i3.15538.
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ABSTRACTObjective: The synthesis of nanoparticles (NPs) has become a matter of great interest in recent times due to their various advantageous propertiesand applications in a variety of fields. Metal NPs are being increasingly used in many sectors, and there is growing interest in the biological andenvironmental safety of their production.Methods: In this study, iron oxide NPs (Fe3O4-NPs) were synthesized from fruits of Ficus carica using a rapid, single step and completely greenbiosynthetic method by reduction of ferrous sulfate solution with F. carica ethanolic extract. The prepared Fe3O4-NPs were investigated by X-raydiffraction, Fourier transform infrared spectroscopy, and ultraviolet-visible spectroscopy.Results: The report emphasizes the effect of superparamagnetic Fe3O4-NPs on the degradation rate of hazardous dyes acid blue.Conclusion: To conclude, Fe3O4-NPs were prepared from fruits of F. carica using a rapid, single step and completely green biosynthetic method byreduction of ferrous sulfate solution with F. carica ethanolic extract.Keywords: Ficus carica, Ethanolic extract, Reduction, Ferrous sulfate, Superparamagnetic iron oxide nano particles, Dye degradation.
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Umeh, SI, IP Umunna, and JU Udensi. "Inhibition of dehydrogenase activity in S. typhimurium by ethanolic and methanolic extracts of Carica papaya and Ocimum gratissimum." Bio-Research 18, no. 1 (April 16, 2020): 1078–84. http://dx.doi.org/10.4314/br.v18i1.2.
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Dehydrogenase and inhibitions of dehydrogenase activities in Salmonella typhimurium by ethanolic and methanolic leaf extracts of Ocimum gratissimum and Carica papaya were investigated. Dehydrogenase activity assay was carried out using 2, 3, 5-triphenyl tetrazolium chloride (TTC) as the electron acceptor. Pure culture of S. typhimurium was exposed to varied concentrations of ethanolic and methanolic extracts of Ocimum gratissimum and Carica papaya [0-4000 μg/ml]. The ethanolic and methanolic extracts exhibited a concentration dependent response against the tested organism. Results obtained revealed that the ethanolic extracts showed a higher bactericidal effect on the test organism than the methanolic extracts at the threshold and total inhibitory concentrations. The IC50 were 45.349 and 15.697; IC100 were 43.732 and 35.526 for ethanolic extracts of Carica papaya and Ocimum gratissimum respectively while the IC50 were 7.108 and 13.696; IC100 were 40.815 and 31.104 for methanolic extracts of Carica papaya and Ocimum gratissimum respectively. This in-vitro study further revealed that the leaf of Carica papaya was more potent on Salmonella typhimurium than the leaf of Ocimum gratissimum. The findings from this study seem to provide the in-vitro evidence that justifies Carica papaya and Ocimum gratissimum as good candidate medicinal plants for the potential treatment of Salmonella typhimurium infections.
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Irum, Zoobia, Amer Hassan Siddiqui, Fariha Ahmad Khan, Fouzia Perveen, Asia Firdous, and Neelofer Yousaf. "Xanthine Oxidase Inhibitory Activity of Ethanolic Extract of Ficus Carica Fruit." Pakistan Journal of Medical and Health Sciences 17, no. 1 (January 31, 2023): 304–6. http://dx.doi.org/10.53350/pjmhs2023171304.
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Hyperuricemia is a purine metabolism disorder characterised by an excess of uric acid in the blood and considered as a risk factor for gout, coronary heart disease, hypertension, diabetes, and a variety of other illnesses. Xanthine oxidase inhibitors have key role in management of hyperuricemia and related disorders but multiple adverse effects associated with these agents have minimized their chronic use. Ficus carica fruit has been widely used around world as a therapeutic agent for several disorders. In traditional medicine it has been used to treat gouty arthritis but the effect has not been scientifically established so far. Objective: This study was conducted to assess the in vitro xanthine oxidase inhibition of Ficus carica fruit extract. Method: The ethanolic extract of Ficus carica fruit was evaluated in vitro at five different doses for its xanthine oxidase inhibition. Xanthine oxidase inhibitory activity was measured spectrophotometrically and inhibitory concentration IC 50 was calculated. The dose dependant inhibition of Ficus carica fruit was compared with inhibition of standard drug allopurinol. Results: Ficus carica fruit extract was found to possess xanthine oxidase inhibition with IC50 27.5 µg/ml in comparison to the allopurinol with IC50 11.0 µg/ml.Thus the agent can be used as alternative to standard drug allopurinol for treatment of hyperuricemia and related disorders. Conclusion: The study showed that Ficus carica fruit has potential to inhibit the xanthine oxidase so can be used as natural source to treat gout and many other xanthine oxidase related medical disorders. Keywords: Ficus carica Extract (FCE), Xanthine Oxidase (XO), Xanthine Oxidase Inhibition (XOI), Hyperuricemeia (HU).
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Ruslan, Fadhilah nur azizah, and Armanto Makmun. "Beberapa Khasiat Buah Tin (Ficus Carica) Dari Antikonvulsan, Anti Alergik, Anti Inflamasi, Antihiperglikemik, Antitumor, Anti Kanker Hingga Terapi Hati." Unram Medical Journal 9, no. 3 (October 17, 2020): 184–201. http://dx.doi.org/10.29303/jku.v9i3.409.
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Buah tin (Ficus carica) adalah sumber zat besi, kalsium, fosfor, dan serat. Buah tin telah digunakan di seluruh dunia untuk mengobati berbagai gangguan kesehatan. Ficus carica Berasal dari Timur Tengah dan Asia Barat, tetapi menyebar ke banyak wilayah lain di dunia. Produk dari Ficus carica banyak digunakan sebagai sumber makanan dan obat-obatan untuk mengobati berbagai penyakit. Berdasarkan uraian yang disebutkan, maka peneliti tertarik untuk mengkaji lebih lanjut mengenai manfaat yang terkandung dalam Buah tin.
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Scannabue, Aristarco. "La carica dei 600." HISTORIA MAGISTRA, no. 22 (March 2017): 170–74. http://dx.doi.org/10.3280/hm2016-022017.
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Blanco, Carlos, Nancy Ortega, Rodolfo Castillo, María Alvarez, Antonio G. Dumpierrez, and Teresa Carillo. "Carica papaya Pollen Allergy." Annals of Allergy, Asthma & Immunology 81, no. 2 (August 1998): 171–75. http://dx.doi.org/10.1016/s1081-1206(10)62805-0.
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Wulan, Sekar Sari, Moh Su’i, and Enny Sumaryati. "PENGARUH KONSENTRASI GARAM DAN LAMA PERENDAMAN TERHADAP MUTU MANISAN CARICA (Carica pubescens)." Agrika 13, no. 1 (May 31, 2019): 23. http://dx.doi.org/10.31328/ja.v13i1.987.
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Buah carica merupakan buah yang mengandung vitamin C dan asam oksalat tinggi. Untuk meningkatkan daya guna buah carica dilakukan diversifikasi pangan dengan membuat manisan. Tujuan penelitian ini adalah mendapatkan konsentrasi garam terbaik dan lama perendaman dalam pembuatan manisan carica. Penelitian ini merupakan penelitian ekperimental 2 faktor yang disusun secara faktorial menggunakan Rancangan Acak Kelompok (RAK). Faktor pertama adalah konsentrasi garam terdiri dari 3 level yaitu 3%, 6%, 9%. Faktor kedua yaitu lama perendaman yang terdiri dari 2 level yaitu 15 menit dan 30 menit. Masing-masing perlakuan diulang tiga kali. Hasil penelitian menunjukkan bahwa kadar vitamin C 24.35mg/100g-31.48mg/100g, total asam 0.21-0.27%, kalsium oksalat 2550- 3750mg/100g, tekstur 267.167-391.975 g/mm2 dan organoleptik pada level suka terdiri atas rasa 3-4.1, warna 3.3-3.9, aroma 3.4-3.6, tekstur 3-3.6, rasa gatal 2.5-3.2. Hasil analisa statistik menunjukkan bahwa interaksi kedua faktor berpengaruh nyata terhadap vitamin C, total asam, kalsium oksalat, rasa, aroma, warna, tekstur, rasa gatal.
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Ayyildiz, Hamide Filiz. "Evaluation of Chemical Properties of Cold Pressed Ficus Carica Seed Oil." Pakistan Journal of Analytical & Environmental Chemistry 22, no. 1 (June 23, 2021): 35–43. http://dx.doi.org/10.21743/pjaec/2021.06.05.
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Free fatty acid, peroxide value , conjugated diene and triene, chlorophyll, β-carotene, fatty acid composition, triglyceride, tocol (tocopherol and tocotrienol) compositions, sterol, wax and total polymeric compound amounts of cold pressed Ficus carica seed oil were evaluated by using chromatographic and spectrometric methods in this study. While the % free fatty acid of cold pressed ficus carica seed oil was 0.76±0.06, the peroxide value was found as 1.06 ± 0.09 meqO2/kg. It also had low content of conjugated diene and triene amounts, chlorophyll, wax and total polymeric compounds. The obtained results demonstrated that cold pressed ficus carica seed oil had rich linolenic and linoleic acid, and contained high amounts of Linoleic- Linolenic- Linolenic, Linolenic- Linolenic- Linolenic, Olenic- Linoleic– Linolenictriglycerides. Cold pressed ficus carica had a high content of β-carotene (4114.9 ppm), total tocol (1006 ppm) and sterol (7250.83 ppm). The obtained results showed that ficus carica seed oil is a product with superior properties due to its high nutritional value and beneficial phytochemicals. Therefore this oil can be an alternative to vegetable oils and used as a medical product.
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Liling, Vania V., Yessie K. Lengkey, Christel N. Sambou, and Reky R. Palandi. "Uji Aktivitas Antibakteri Ekstrak Etanol Kulit Buah Pepaya Carica papaya L. Terhadap Bakteri Penyebab Jerawat Propionibacterium acnes." Biofarmasetikal Tropis 3, no. 1 (May 11, 2020): 112–21. http://dx.doi.org/10.55724/j.biofar.trop.v3i1.266.
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Kulit buah pepaya jarang digunakan masyarakat sebagai obat tradisional, padahal kulit buah pepaya memiliki kandungan gizi yang hampir mirip dengan daging buahnya. Kulit buah pepaya Carica papaya L. mengandung senyawa antibakteri seperti alkaloid, tanin, steroid, saponin, flavonoid. Bakteri Propionibacterium acnes merupakan bakteri flora normal pada kulit yang berperan dalam pembentukan jerawat. Tujuan penelitian untuk mengetahui nilai zona hambat dari ekstrak kulit buah pepaya Carica papaya L. terhadap bakteri penyebab jerawat P. acnes. Jenis penelitian ini adalah eksperimen laboratorium. Uji daya hambat dengan menggunakan metode difusi kertas cakram. Variabel penelitian yaitu konsentrasi ekstrak kulit buah pepaya Carica papaya L. 10µg/50µL, 20µg/50µL, 30µg/50µL, 40µg/50µL, 50µg/50µL dan zona hambat pertumbuhan bakteri P. acnes. Hasil penelitian ini didapatkan ekstrak kulit buah pepaya Carica papaya L. dapat menghambat pertumbuahan bakteri P. acnes pada konsentrasi 20% sampai 100% dengan rata-rata diameter zona hambat 9,83 mm sampai dengan 11,67 mm dengan kategori sedang hingga kuat. Hal ini menunjukan bahwa ekstrak kulit buah pepaya Carica papaya L. mempunyai pengaruh terhadap pertumbuhan bakteri penyebab jerawat P. acnes.
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Hayati, Inayah, and Windi Terza Ayuputri. "LAMA WAKTU KEMATIAN Pediculus humanus capitis dengan EKSTRAK BIJI PEPAYA California (Carica papaya cv. california)." Jurnal Ilmiah Pharmacy 8, no. 2 (November 15, 2021): 61–70. http://dx.doi.org/10.52161/jiphar.v8i2.358.
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Telah dilakukan penelitian dengan tujuan untuk mengetahui lama waktu kematian kutu kepala Pediculus humanus capitis   dengan menggunakan ekstrak biji pepaya california (Carica papaya cv. California). Penelitian ini dilakukan pada bulan Juni 2020 di Laboratorium Biologi FMIPA Universitas Bengkulu. Penelitian ini menggunakan metode eksperimen yaitu ekstrak biji pepaya california (Carica papaya cv california) diujikan terhadap 90 kutu kepala stadium dewasa dilakukan sebanyak 3 kali pengulangan. Selain itu juga dilakukan pengujian kontrol positif (+) menggunakan pedikulosida kimia dengan kandungan permethrin 1% dan kontrol negatif (-) menggunakan aquadest. Pada kontrol negatif kutu kepala tetap hidup 2 jam setelah pengujian, sedangkan pada kontrol positif menunjukan kematian 100% dengan rata-rata lama waktu kematian 10 menit 20 detik. Pengujian dengan menggunakan ekstrak biji pepaya california (Carica papaya cv Califonia) dapat menyebabkan kematian kutu kepala (Pediculus humanus capitis)  pada konsentrasi 25%, 50%, 75% dan 100%. Pada konsentrasi 100% ekstrak biji pepaya (Carica papaya var.california) menyebabkan kematian paling cepat dengan rata-rata waktu 04  ment 33 detik.Kata kunci : Pediculus, Carica papaya cv.California, Lama kematian
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Mardiyanti, Nurul, Titisari Juwitaningtyas, and Andi Patiware Metaragakusuma. "Quality Control Analysis of Carica Products Based on Sugar Content Parameters in PT AHA, Central Java." Journal of Agri-Food Science and Technology 3, no. 2 (January 25, 2023): 61–66. http://dx.doi.org/10.12928/jafost.v3i2.6444.
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PT AHA is a manufacturing industry company engaged in the processing of carica fruit food in the form of candied syrup (carica in syrup). On PT AHA every day will be carried out quality control to control the quality of carica in syrup. This study contributes to investigating the sugar content of carica in syrup. The sugar level was analyzed using a refractometer, dropper pipette, and toothpick, then the data obtained was analyzed using the SPC method (Statistical Process Control) and this test was carried out for 19 days. The results showed that there were 4 product samples outside the quality control limits, namely day 1 (22.1% Brix), day 6 (21.8% Brix), day 9 (18.3% Brix) and day 13(22.0 %Brix). Only 1 sample is found that exceeds the quality control limit, namely on day 1, while the others are still under control. The difference in sugar content in carica products is possible because when entering sugar using a manual scale, errors can occur when reading the weight.
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Kristanti, Nency, Dewi Larasati, and Ika Fitriana. "Kandungan Pewarna, Pengawet, Dan Pemanis Pada Carica In Sirup Kemasan Cup Di Kecamatan Mojotengah, Kabupaten Wonosobo." Jurnal Teknologi Pangan dan Hasil Pertanian 14, no. 2 (June 13, 2019): 6. http://dx.doi.org/10.26623/jtphp.v14i2.2444.
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<p class="Default">Produk carica in sirup yang tersusun atas komponen buah carica, air, dan gula. Produk ini merupakan produk dengan kadar air tinggi sehingga cepat rusak selama penyimpanan. Oleh karena itu, untuk memperpanjang umur simpan serta meningkatkan mutu produk, diperlukan bahan tambahan pangan (BTP). Adanya kecenderungan penggunaan bahan tambahan pangan seperti pewarna, pengawet, dan pemanis oleh para produsen carica resiko kesehatan bila mengkonsumsi produk tersebut. Maka dari itu, perlu dilakukan penelitian survey tentang penggunaan bahan tambahan pangan (BTP) seperti pewarna, pengawet, dan pemanis pada produk carica in sirup di Kecamatan Mojotengah, Kabupaten Wonosobo. Tujuan dari penelitian ini adalah untuk mengetahui kandungan bahan tambahan pangan meliputi pewarna (Tartrazin, Kuning FCF), pengawet (Asam Benzoat, Asam Sorbat), dan pemanis (sakarin) yang digunakan pada manisan carica in sirup di Kecamatan Mojotengah, Kabupaten Wonosobo. Penelitian dilaksanakan pada bulan November 2019–Februari 2020 di Laboratorium Kimia pada Balai Besar Pengawas Obat dan Makanan Semarang, Provinsi Jawa Tengah, menggunakan bahan baku carica dalam sirup yang diperoleh dari Kabupaten Wonosobo. Penelitian dilakukan menggunakan survey dengan metode sampling. Untuk menentukan sampel dengan metode sampling maka seluruh populasi sampel yang jumlahnya kurang dari 100 dijadikan subjek penelitian. Hasil penelitian menunjukkan bahwa hasil kuisioner menunjukkan bahwa tingkat pengetahuan perusahaan tentang Bahan Tambahan Pangan 80% sudah tahu. Dan dari hasil survey menunjukkan bahwa perusahaan yang menggunakan pengawet 40% , pewarna 60% dan memenuhi persyaratan.</p>
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Gul, Somia, Sabeen Raza, Zaira Rashid, Maria Ayub, and Ghulam Sarwar. "Neuropharmacological screening of Ficus Carica Linn; Fruit for Anxiolytic and Antidepressant Activity." Bangladesh Journal of Medical Science 17, no. 4 (September 19, 2018): 606–11. http://dx.doi.org/10.3329/bjms.v17i4.38323.
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Background: Rutin and polyphenol which are present in ficus carica linn are responsible for anti-depressant and anxiolytics effect.Aims: We have conducted the study to evaluate the anti depressant and anxiolytic effect of ficuscaricalinn on mice and compare its effect with well known prescribed anti depressant and anxiolytic drug alprazolam.Methods: Three groups of mice were marked as Control, Reference and Test. Each group comprise of 5 mice. Control group was on normal diet. Reference group was feeded alprazolam at a dose of 0.5mg/60kg while test group were provided two different dilution of ficuscaricalinn, one dilution is 250mg/ kg/100ml of water and second dilution is 500mg/kg/100ml of water. We used Light/dark box method and Elevated plus maze method to evaluate the anxiolytic effect of ficus carica linn. To determine the anti-depressant effect of ficus carica linn.Results: we was used one method that is Head Dip Method. Results were collected and observed readings and data were clearly indicating the great and pronounced anti depressant and anxiolytic effect of ficus carica linn at a dose of 500mg/kg compare with a widely prescribed drug alprazolam for its anti-depressant and anxiolytic effect.Ficus carica is well known for its numerous biological activities also found to be one of excellent distressing agent. Stress provoking several disorders could be limit by the use of ficus carica fruit in doses 250mg/kg and 500mg/kg. Ficus carica linn as a natural product may prove better therapeutic agent if more study is conducted on it.Conclusion: As this study is confined to the mice, there’s much possibilities to have similar effect in humans but require more work on it.Bangladesh Journal of Medical Science Vol.17(4) 2018 p.606-611
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AGOREYO, B. O., O. BRUME–ERUAGBERE, and O. OLOWU. "OXIDATIVE STRESS AND CHANGES IN THE LEVELS OF ANTIOXIDANT ENZYMES OF TWO VARIETIES OF Carica papaya L. DURING RIPENING." Nigerian Journal of Life Sciences (ISSN: 2276-7029) 3, no. 1 (March 1, 2013): 1–9. http://dx.doi.org/10.52417/njls.v3i1.100.
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Oxidative stress and changes in the levels of antioxidant enzymes were determined in two varieties of Carica papaya fruits (?Agric pawpaw‘: oblong shaped variety and ?Local pawpaw‘: pear shaped variety) during ripening. An increase in lipid peroxidation product, malondialdehyde (MDA); which is an index of oxidative stress, was observed in both varieties. The activity of the antioxidant enzyme, superoxide dismutase (SOD) also decreased in both varieties of Carica papaya fruits during ripening and its reduction was observed to be the major contributor to oxidative stress in Carica papaya fruits. Changes in catalase (CAT) and ascorbate peroxidase (APX) activities during ripening in Carica papaya fruits in this study were found to be dependent on the type of variety. Increase in catalase activity was observed throughout the ripening period in ?Local pawpaw‘ (pear shaped variety) (from 0.000212 ± 0.000001 to 0.000917 ± 000025 ?mole/min/g fresh weight), while in ?Agric pawpaw‘ (oblong shaped variety), the catalase activity increased from the unripe to the ripe stage (from 0.000071 ± 0.000024 to 0.000155 ± 0.000026 ?mole/min/g fresh weight) and later decreased in the overripe stage (from 0.000155 ± 0.000026 to 0.000099 ± 0.000029 ?mole/min/g fresh weight). The only changes that were observed in the activity of ascorbate peroxidase in the two varieties of Carica papaya fruits were an increase in the overripe stage of ?Local pawpaw‘ (pear shaped variety) (from 0.001427± 0.000618 to 0.002497 ± 0. 000619 ?mole/min/g fresh weight) and a decrease in the overripe stage of ?Agric pawpaw‘ (oblong shaped variety) (from 0.002497± 0.000618 to 0.0014267 ± 0.000617 ?mole/min/g fresh weight). This study revealed that reduction in superoxide dismutase (SOD) activity was a major contributor to oxidative stress in Carica papaya fruits during ripening. It also showed that the increase in oxidative stress in Carica papaya fruit during ripening contributes to its high perishability.
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Aprilia, Lely. "PENGARUH PEMBERIAN INFUSA CARICA PAPAYA TERHADAP NYERI DISMINORE PRIMER PADA MAHASISWA." JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan P-ISSN : 1979-3340 e-ISSN : 2685-7987 11, no. 1 (August 1, 2019): 26–31. http://dx.doi.org/10.36089/job.v11i1.26.
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Primary dysmenorrhea is a pain that occursduring menstruation, without any infection of thepelvis and without abnormalities in the genitals of thereal. Ideally, disminore is natural to be experiencedby adolescents, when disminore pain is categorizedas severe it will affect daily activities. Based on thepreliminary study results, 60 female universitystudents received primary disinfectant. The aim is toanalyze the effect of giving carica papaya infusion toprimary dismalore on Midwifery student. This research uses pre experimental designwith One group Pretest posttest Design approach.Independent variables are carica papaya infusa anddependent variable is primary disminore pain. Thepopulation of this research were 60 female studentswho suffered primary disinfecting and the sampleswere 16 respondents using non-probability samplingtechnique with accidental sampling technique.Instruments used in pain scale observation sheetswere analyzed using Paired Sample T-Test statistictest. Based on the results of the research beforegiving carica papaya infusa there are 16 studentswho experienced primary disminore and after giveninfusa carica papaya all students experienceddecreased pain scale disminore. Result of statisticaltest of Paired Sample T-Test, got pain scale pre andpost result got result p value <a or (0,000 <0,05) soHa accepted. This suggests that there is an effect ofdisminary pain scale between before and aftertreatment of carica papaya infusa. It is expected that female students whoexperience disminore pain to get used tononpharmacology therapy to reduce pain like one ofthem by drinking carica papaya infusa.
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Martial-Didier, Adingra Kouassi, Konan Kouassi Hubert, Kouadio Eugène Jean Parfait, and Tano Kablan. "Phytochemical Properties and Proximate Composition of Papaya (Carica papaya L. var solo 8) Peels." Turkish Journal of Agriculture - Food Science and Technology 5, no. 6 (July 13, 2017): 676. http://dx.doi.org/10.24925/turjaf.v5i6.676-680.1154.
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Papaya (Carica papaya) is a common tropical fruit used for nutrition as well as medicinal purposes. Apart from fruit, seed, latex and other plant parts of papaya tree have been shown to have medicinal properties. Since, no systematic study has been performed on nutritional analysis of papaya (Carica papaya L. var solo 8) peels. In this study, the proximate composition, mineral element profile and phytochemical composition of papaya (Carica papaya L. var solo 8) peels were investigated. The peels were harvested fresh, dried in an oven at 45°C for 48 hours, ground and analyzed according to standard procedures. Proximate analysis showed high level of proteins (11.67 ± 0.04 %), crude fibre (32.51 ± 0.03 %), carbohydrate (47.33 ± 0.08 %), ash (5.98 ± 0.03 %) 0.03 %) and fat (2.51 ± 0.13 %). Mineral analysis indicated the papaya (Carica papaya L. var solo 8) peels were specifically rich in potassium and phosphorus. Potassium was found to be the most abundant mineral present in the peels (516.33 ± 0.82 mg/100g). Phytochemical composition showed high level of total phenolic (65.48 ± 0.39 mg (GAE)/100 g DW), flavonoids (5.58 ± 0.83 mg (QE)/100 g DW) and tannins (10.51 ± 0.93 mg (TAE)/100 g DW). The methanolic extracts of the papaya (Carica papaya L. var solo 8) peels exhibited the high DPPH radical scavenging activities (81.89 ± 0.14 %).These data indicated that this papaya (Carica papaya L. var solo 8) peels could constitute a potential good source of natural antioxidant for local population.
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Sultana, Afroza, Asma Khan, Rumana Afroz, Onayza Yasmeen, Muqbula Tasrin Aktar, and Md Abdullah Yusuf. "Comparison of Anti-Inflammatory Effect of Ethanolic Extract of Carica Papaya Leaves and Indomethacin in Carrageenan Induced Rat Paw Edema Animal Model." Journal of Science Foundation 16, no. 2 (April 1, 2019): 49–53. http://dx.doi.org/10.3329/jsf.v16i2.40869.
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Background: Carica papaya is very useful vegetables for daily living.
Objective: The purpose of the present study was to compare the anti-inflammatory effect of ethanolic extract of Carica papaya leaves and indomethacin in carrageenan induced rat paw edema animal model.
Methodology: This was an animal study carried out in the Department of Pharmacology at Dhaka Medical College, Dhaka, Bangladesh during the period from July 2014 to June 2015 for a period of one (01) year. The leaves of Carica Papaya collected from Botanical garden, Mirpur, Dhaka, Bangladesh. The animals were divided into four groups. Inflammation was produced by injecting 0.1 ml of 1% carrageenan solution in normal saline in all experimental animals. Group I were served as control that received normal saline. Group II were received ethanolic extract of Carica Papaya. Group III were received ethanolic extract of Carica Papaya leaves. Group IV were received indomethacin.
Result: The experiment was carried out on 48 Long Evan Norwegian rats. Rats were divided in 4 groups of six animals each. The mean initial antero-posterior diameter of rat’s paw of group I, II, III and IV were 3.83±0.04, 2.12±0.02, 1.74±0.01 and 1.60±0.03 respectively. The inhibition of edema formation were 44.64%, 54.57% and 58.22% in group II, III and IV respectively.
Conclusion: In conclusion the Carica papaya leaves has anti-inflammatory effect
Journal of Science Foundation 2018;16(2):49-53
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Jannah, Amalia Nur, Amilia Yuni Damayanti, and Fathimah Fathimah. "PENGARUH PEMBERIAN BUAH TIN (FICUS CARICA) TERHADAP PENURUNAN TEKANAN DARAH." Jurnal Kesehatan Tambusai 2, no. 1 (March 31, 2021): 15–21. http://dx.doi.org/10.31004/jkt.v2i1.1526.
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Tekanan darah tinggi adalah salah satu penyakit dan sebagai faktor risiko penyakit tidak menular lainnya. Buah tin (Ficus carica) yang mengandung antioksidan seperti flavonoid dan kalium, dan berpotensi menurunkan tekanan darah. Mengetahui pengaruh buah tin (Ficus carica) terhadap tekanan darah di Universitas Darussalam Gontor, Kampus Gontor Putri 1 dan 2. Quasy eksperimental menggunakan desain kelompok kontrol pre-post test dan pengambilan sampel purposif yang dibagi menjadi 2 kelompok, kelompok intervensi dan kontrol dengan 17 orang setiap kelompok. Kelompok intervensi diberikan buah tin (Ficus carica) berdasarkan perhitungan dosis sesuai dengan konversi laurance, sementara kelompok kontrol hanya melakukan penarikan 24 jam sekali per dua hari. Hasilnya dianalisis dengan tes t berpasangan untuk menentukan perbedaan tekanan darah sebelum dan sesudah perawatan. Tes t independen dilakukan untuk menentukan perbedaan tekanan darah antara kelompok intervensi dan kontrol setelah perawatan. Buah tin (Ficus carica) memiliki efek pada pengurangan tekanan darah sistolik (p = 0,000) dan tekanan darah diastolik (p = 0,001). Tidak ada perbedaan yang signifikan antara kelompok intervensi dan kontrol (p = 0,599) pada tekanan darah systolik dan diastolik (p = 0,705). Buah tin (Ficus carica) dapat menurunkan tekanan darah, tetapi tidak ada perbedaan yang signifikan antara kelompok intervensi dan kontrol.
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Kiran, Bondada V. V. S. Surya, Surada Vijaya Lakshmi, Nimmakayala Sridhar, and Lakshmi Kanta Kanthal. "Screening of antibacterial and anthelmintic potentials of Tamarindus indica and Carica papaya." Journal of Phytopharmacology 2, no. 6 (December 25, 2013): 8–13. http://dx.doi.org/10.31254/phyto.2013.2602.
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The present study was aimed to evaluate the antibacterial and anthelmintic evaluation of methanolic and aqueous extracts of leaves of Tamarindus indica, latex of Carica papaya. The antibacterial activity was evaluated by cup diffusion method against both gram positive and gram negative bacteria. Methanol extract of Carica papaya latex showed maximum activity against Bacillus subtilis (IZ: 29±0.35mm; AI: 1.318). The anthelmintic profile of various extracts of leaves of Tamarindus indica, latex of Carica papaya showed that aqueous extracts of Tamarindus indica greater potency to produce paralysis earlier than other extracts.
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Sukowati, Siski Andini, Zulhan Arif, and Rudi Heryanto. "Effect of Roasting Process on Antioxidant Activity of Carica Seeds Coffee (Carica pubescens)." Indonesian Journal of Chemical Studies 1, no. 2 (July 28, 2022): 32–38. http://dx.doi.org/10.55749/ijcs.v1i2.13.
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Carica seeds (Carica pubescens), one of the diversification of coffee drinks, served as antioxidants. The roasting process generated degradation of secondary metabolic compounds but produced Maillard reactions products (MRPs). The study aimed to determine the effect of the roasting process on the antioxidant activity of Carica coffee beans and its correlation to the Maillard reaction. The samples roasting temperatures were 100–115, 150–165, and 200–215 °C. The samples were analyzed for proximate, total phenolic, antioxidant, and FTIR. The moisture and ash content of dry seeds were according to SNI 01-2907-2008. The total phenolic content was 3.21–8.99 µgGAE/g, with the highest contents at 200–215 °C. The antioxidant activity was 83–459.67 ppm AEAC. The high phenolic content and antioxidant at 200–215 °C were thought to come from MRPs compounds. The FTIR spectra showed stretching of OH, C=C (aromatic), C=N, C=O, and C-OH (phenol). The spectrum intensity weakened at higher temperatures. However, only the nC–H stretching at 200–215 °C became stronger. The Cluster Ward analysis showed resemblance spectra at roasting temperature levels of 100–115 and 150–165 °C. The roasting process affected the antioxidant activity of Carica coffee beans, thereby increasing the roasting temperature level. This condition resulted in higher levels of antioxidants.
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Trisna, Citra, and Mardyana Nizar. "AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL KULIT BUAH PEPAYA MUDA (CARICCA PAPAYA L) TERHADAP ESCHERICHIA COLI DAN STAPHYLOCOCCUS AUREUS SECARA IN VITRO." Jurnal Medikes (Media Informasi Kesehatan) 5, no. 2 (November 30, 2018): 96–103. http://dx.doi.org/10.36743/medikes.v5i2.51.
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Penyakit infeksi yang disebabkan oleh bakteri, memerlukan antibiotika untuk pengobatannya. Pemakaian antibiotika yang tidak tepat menyebabkan terjadinya resistensi. Beberapa penelitian melakukan penelitian terhadap tanaman yang dapat digunakan untuk pengobatan penyakit infeksi. Dari penelitian didapatkan banyak tanaman obat yang digunakan untuk menyembuhkan penyakit infeksi. Salah satu diantaranya adalah tanaman pepaya (Carica papaya L). Tujuan penelitian ini adalah untuk mengetahui zat aktif pada kulit buah Carica papaya L yang berfungsi sebagai antibakteri dan mengetahui aktivitas ekstrak etanol kulit buah pepaya muda (Carica papaya L) terhadapa bakteri E. coli dan Staphylococcus aureus. Jenis penelitian ini adalah eksperimen laboratoratorium. Sampel pada penelitian ini sebanyak 3 kg kulit buah Carica papaya L. Dilakukan ekstraksi etanol kulit buah Carica papaya L untuk mengetahui kandungan metabolit sekunder. Dilakukan uji fitokimia untuk mengetahui kandungan antibakteri pada sampel, selanjutnya dilakukan uji aktivitas antibakteri terhadap bakteri E. coli dan Staphylococcus aureus, dengan konsentrasi 25%, 50%, 75% dan 100%. Hasil uji fitokimia didapatkan kandungan positif plafonoid, saponin dan steroid. Pada uji aktivitas antibakteri ekstrak etanol 96% terhadap E. coli tidak ditemukan daya hambat pada semua konsentrasi. Hasil uji aktivitas antibakteri terhadap bakteri Stapylococcus aureus, didapatkan daya hambat mulai dari konsentrasi 25% sebesar 0,55 mm daya hambat tertinggi pada konsentrasi 100% sebesar 2,95 mm
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Rifaath, Mohamed. "Effect of Carica papaya on beta catenin and Wnt mRNA expression in human colon cancer (HT-29) cells in vitro." Bioinformation 18, no. 3 (March 31, 2022): 289–92. http://dx.doi.org/10.6026/97320630018289.
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Colon cancer is the third most frequent cancer in humans. Carica papaya leaves are vegetable foods consumed by most people around the world; it has potential as an anticancer. Therefore it is of interest to investigate the effect of Carica papaya on beta catenin and Wnt mRNA expression in human colon cancer (HT-29) cells in vitro. Human Colon cancer cell line (HT-29) was purchased from the National Centre for Cell Sciences, Pune, India. Cell viability test was done by MTT assay. Gene expression analysis was done by Real Time-PCR. The obtained data were analyzed statistically by one-way analysis of variance and Duncan's multiple range test with Graph Pad Prism version 5 to analyze the significance of individual variations among the control and experimental groups. The significance was considered at p<0.05 level in Duncan's test. Carica papaya caused a marked increase in cell death in a dose dependent manner. At the end of 48 hours, maximum inhibition was at 300 and 400 μg/ml. Carica papaya has significantly reduced the mRNA expression of Wnt and beta catenin (p<0.05). Data showed that Carica papaya leaf extract has anticancer activity on Colon cancer cell lines (HT-29).
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Ahmed, Zubair, and Shobha Kamble. "Antinociceptive Action of the Seeds of Carica Papaya Linn Extracted in Aqueous Medium in Mice." Biomedical and Pharmacology Journal 11, no. 1 (March 25, 2018): 197–200. http://dx.doi.org/10.13005/bpj/1363.
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To study the antinociceptive action of the seeds of carica papaya linn extracted in aqueous medium (CPE) in mice. The Carica Papaya aqueous seed extract was evaluated for its antinociceptive effect in mice by producing writhing using acetic acid. One hour after administration of mice with the test, control and the standard drugs the mice were given 0.2 ml of acetic acid (3%) solution intraperitoneally to produce writhing. The number of constrictions of abdominal muscles induced along with extending and jerking of the hind limb were counted from 5 to 15 minutes. The response of the mice treated with the carica papaya aqueous seed extract and that of the standard drug treated groups were compared with those of the mice in the control group. Percentage inhibition of the writhing movements in mice was considered as an index of analgesic effect. The Carica Papaya aqueous seed extract reduced the number of writhing in test group 5 (CPE 400 mg/kg) significantly (P < 0.05) in comparison to the control group. Percentage inhibition in test group 5 (60.8%) was comparable to the percentage inhibition in the standard drug (diclofenac) group (70.3%). The Carica Papaya aqueous seed extract showed significant antinociceptive effect in mice.
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Diab, Abdel Aziz A., Mansour H. Zahra, Mai S. Attia, and Ahmed M. Shehata. "Physiological and biochemical studies on the protective effect of Ficus carica leaf extract, vitamin C or their combination on liver toxicity induced by lead acetate in male rats." Biomedical Research and Therapy 5, no. 10 (October 18, 2018): 2733–45. http://dx.doi.org/10.15419/bmrat.v5i10.488.
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Introduction: Lead is an environmental contaminant, which is toxic to organ systems in human and other animals. The present study investigated the possible protective role of Ficus carica leaf extract, vitamin C or the combined treatment in lead acetate-induced hepatotoxicity.
Methods: One hundred and twenty-six adult male albino rats were divided into seven groups (n = 18). G1 (control group) received distilled water. G2 (lead acetate group) received lead acetate at a daily dose of 20 mg/kg body weight by gastric gavage. G3 (Ficus carica group) received Ficus carica leaves extract at a daily dose of 200 mg/kg body weight by gastric gavage. G4 (Ficus and lead group) received Ficus carica leaves extract followed by lead acetate after 20 minutes. G5 (vitamin C group) received vitamin C at a daily dose of 200 mg/kg body weight by gastric gavage, G6 (vitamin c and lead group) received vitamin C followed by lead acetate after 20 minutes. And, G7 (Ficus, vitamin C, and lead group) received Ficus carica leaves extract and vitamin C followed by lead acetate after 20 minutes. The treatment extended for six weeks, blood and specimens were collected at a 2-week interval. Serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), total protein (TP), direct bilirubin (DB), lipid peroxidation biomarker (Malondialdehyde (MDA)), antioxidants enzymes (Superoxide dismutase (SOD) and reduced glutathione (GSH)) in liver tissue and histopathological changes in liver were investigated.
Results: Lead acetate caused significant increases in AST, ALT, ALP, DB and MDA levels. In addition, TP and level of SOD and GSH significantly decreased compared to the control group. The pre-treatment with the combination of Ficus carica and vitamin C improved liver parameters, the level of antioxidant enzymes as well as histopathological changes.
Conclusion: The combination of Ficus carica leaf extract and vitamin C had a remarkable protective action against lead acetate induced- oxidative damage in rats.
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Nishimura, Kosaku, Keisuke Higashiya, Naoki Ueshima, Kenji Kojima, Teisuke Takita, Tatsuya Abe, Toru Takahashi, and Kiyoshi Yasukawa. "Insight into the collagen-degrading activity of a serine protease in the latex of Ficus carica cultivar Masui Dauphine." Bioscience, Biotechnology, and Biochemistry 85, no. 5 (February 13, 2021): 1147–56. http://dx.doi.org/10.1093/bbb/zbab025.
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ABSTRACT Ficus carica produces, in addition to the cysteine protease ficin, a serine protease. Earlier study on a serine protease from F. carica cultivar Brown Turkey showed that it specifically degraded collagen. In this study, we characterized the collagenolytic activity of a serine protease in the latex of F. carica cultivar Masui Dauphine. The serine protease degraded denatured, but not undenatured, acid-solubilized type I collagen. It also degraded bovine serum albumin, while the collagenase from Clostridium histolyticum did not. These results indicated that the serine protease in Masui Dauphine is not collagen-specific. The protease was purified to homogeneity by two-dimensional gel electrophoresis, and its partial amino acid sequence was determined by liquid chromatography-tandem mass spectrometry. BLAST searches against the Viridiplantae (green plants) genome database revealed that the serine protease was a subtilisin-like protease. Our results contrast with the results of the earlier study stating that the serine protease from F. carica is collagen-specific.
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Maimunah, Morshidi, R. M. Manshardt, and Francis Zee. "Isozyme Variability in Wild and Cultivated Carica papaya." HortScience 30, no. 4 (July 1995): 809A—809. http://dx.doi.org/10.21273/hortsci.30.4.809a.
Full textAbstract:
Populations of wild Carica papaya, previously designated as Carica peltata, were sampled from its native range on the Caribbean coast of Central America (Mexico, Belize, Guatemala, Honduras) and cultivated Carica papaya from both Central and South America were examined for isozyme variability. Thirteen loci from nine enzyme systems (Pgm, Pgi, Idh, Mdh, 6Pgd, Ugpp, Skdh, Aco, Tpi) were scored for all populations. Ten loci were polymorphic and a total of 31 alleles were detected. Isozyme genotypes as determined through segregation analysis were used in the genetic interpretation for eight loci and 18 alleles while six additional loci and 13 alleles were postulated on the basis of phenotypic variation found throughout the species. Nei's genetic identity, I, for both cultivated and wild Carica papaya was >0.9, which is consistent with conspecific populations. Wild papaya populations from different geographic areas appear more related to one another than to domesticates in the same geographic region.